fMRI_Connectivity/resources/BSM_Class/BSM.m

442 lines
18 KiB
Matlab

classdef BSM<handle
%BSM Summary of this class goes here
% Detailed explanation goes here
properties %public properties
SPMs={}; %field to contain the full path of all SPM.mat files to be analysed
Acfl %columns in SPM.xX.X to ignore
Type=4; %BSM type 1..4 5: none %default is option 4
KeepMP = false; %retain Motion paramters
Prefix = 'bs'; %beta series prefix
Clean = true;
end
properties (Access = private)%private properties
SPM_orig %temporary storage for SPM.mat file
ActiveColumns %store the columns to be analized
U_orig %store the U field of SPM
TargetFolder %target folder
% option below obsolete?
BSMToolboxPath%store path to BSMToolbox
SPMPath;%store path to SPM folder
SPMIndexList=[];
MonitorState=false;
end
properties (Dependent) %dependent properties
NumSPMs% number of SPM.mat files to process
end
properties (Constant = true)%constants
BSMMethod={'Traditional BSM Rissman et al', 'Adapted BSM Rissman et al', 'Fast approach (Mumford et al)', 'Adapted fast approach','none'};
end
methods %user callable methods
function Monitor(obj,varargin)
if numel(varargin)>1
id = 'BSM:Monitor:TooManyInputs';
msg= sprintf('Too many inputs given.\n Use: \t obj.Monitor\n\tobj.Monitor(true)\n\tobj.monitor(false)\n');
throw(MException(id,msg))
end
if numel(varargin)==0
obj.MonitorState=xor(obj.MonitorState,true);
else
if ~islogical(varargin{1})
id = 'BSM:Monitor:InputIsNotLogical';
msg= sprintf('Input is not of type logical\n');
throw(MException(id,msg))
end
obj.MonitorState=varargin{1};
end
end
function Calc(obj,varargin)
% obj.calc to apply calculate to all SPM.mat files
% obj.calc(n) to calculated the nth SPM.mat file
% obj.calc([1 3 6]) to indicate which SPM.mat file to calculate
SPMidx=[];% will contain the index to the SPMs to work on
if logical(numel(varargin))
SPMidx=varargin{1};
end
%check number of input arguments
if ~logical(obj.NumSPMs)%nothing to do
fprintf('== == == Nothing to do: done == == ==\n')
return;
end
if isempty(SPMidx)
SPMidx=1:obj.NumSPMs;
end
if ~isnumeric(SPMidx)||~all(isfinite(SPMidx))||min(SPMidx)<1||max(SPMidx)>obj.NumSPMs
id='BSM:Calc:InvalidIndex';
msg='Invalid Index';
throw(MException(id,msg));
end
if numel(SPMidx)>1
obj.SPMIndexList=SPMidx;
SPMidx=obj.SPMIndexList(end);
try
obj.Calc(SPMidx); %handle the single case
catch ME
%if the identifier matches, just continue with next SPM
if ~any(strcmpi(ME.identifier,...
{'BSM:CoreCalc:SPMxBFOrder:invalid'...
,'BSM:CoreCalc:SPMSess:invalid'...
}))
rethrow(ME)
else
disp(ME.message);
end
end
obj.SPMIndexList=obj.SPMIndexList(1:end-1);
if isempty(obj.SPMIndexList)
return;
else
obj.Calc(obj.SPMIndexList);% recursively run the rest of the list
end
else % deal with single entry
obj.CoreCalc(SPMidx)
end
end
end
methods %constructor and set/get methods
function obj = BSM(varargin)
%BSM Construct an instance of this class
%option: parse the info of a matlab batch file? see
%tbx_cf_bsm?
%TODO:
% set default values
obj.SPMPath=[]; %get the SPM path
if nargin>0
[val,TF]=obj.MyGetVal('SPMs',varargin);if TF;obj.SPMs=val;end
[val,TF]=obj.MyGetVal('Type',varargin);if TF;obj.Type=val;end
[val,TF]=obj.MyGetVal('Acfl',varargin);if TF;obj.Acfl=val;end
end
% initialize spm job enviourment
spm_jobman('initcfg');
end
function val=get.NumSPMs(obj)
val=numel(obj.SPMs);
end
function set.SPMPath(obj,~)
SPMFound=which('spm'); %check if SPM in searchpath
if isempty(SPMFound) %SPM not found
error('please add SPM to your path before trying to run BSM');
%to do add a check on spm version
end
obj.SPMPath=fileparts(SPMFound);
end
function set.Clean(obj,varargin)
if isempty(varargin)
%% this option is obsolete
obj.Clean=xor(obj.Clean,true); %togle state
elseif ~islogical(varargin{1})
id = 'BSM:SetClean:InvalidType';
msg= 'Value passed to obj.Clean is not of type logical';
throw(MException(id,msg));
else
obj.Clean=varargin{1};
end
end
function set.Prefix(obj,val)
if ischar(val)
obj.Prefix=val;
else
id='BSM:SetPrefix:InvalidInput';
msg='Input needs to be a char array';
throw(MException(id,msg));
end
end
function set.Type(obj,val)
%check allowed input
if ~isnumeric(val)|| any(~ismember(val,1:5))
id='BSM:Type:invalid';
msg='use a value in the range 1..5';
throw(MException(id,msg));
end
obj.Type=val;
end
function set.Acfl(obj,val)
%allow clearing
if isempty(val)
obj.Acfl=[];
end
if ~isnumeric(val) || any(val<1) || any(~isfinite(val))
id='BSM:Acfl:invalid';
msg='set an array of positive integer values to the Acfl field';
throw(MException(id,msg));
end
obj.Acfl=val;
end
function set.SPMs(obj,val)
%set the SPMs to be analysed
%obj.SPMs=<val>
%possible values for <val>
% {} : clear the SPMs field
% {'ui'} : ask user input
if ~iscell(val)
fprintf('%s\n',...
'Use any of the following options',...
'obj.SPMs={}',...
'obj.SPMs={''ui''}',...
'obj.SPMs={<Ful path to SPM.mat>}');
return
end
if isempty(val) %allow empty input
return;
end
if strcmpi(val{1},'ui')
[P,sts]=spm_select([1 Inf],'mat','select the SPM.mat files',obj.SPMs,pwd,'^SPM.mat');
if ~logical(sts);return;end
if iscell(P)
val=P;
else
val=cellstr(P);
end
end
% capture file not found somewhat clever
TF=cellfun(@exist,val);
if any(not(TF))
id='BSM:SetSPMs:FileNotFound';
msg=sprintf('file not found\t%s\n',val{not(TF)});
throw(MException(id,msg));
end
obj.SPMs=val;
end
end
methods (Access = protected)%private functions
function CoreCalc(obj,idx)
fprintf('working on :%d: %s\n',idx,obj.SPMs{idx});
% how to store the current status of warning and restore curent
WarnStat=warning;
warning('OFF', 'MATLAB:MKDIR:DirectoryExists');
%this try catch block will handle any errors that might ocure
%warning will not remain off by accident
try
SpmFile=obj.SPMs{idx};
load(SpmFile); %#ok<LOAD>
%% exception block
%NB these exception has not been tested properly by the
if (SPM.xBF.order ~=1 ) %#ok<*NODEF>
%TestBSMClass program
%throw an error. The calling function should properly
%handle the error.
id='BSM:CoreCalc:SPMxBFOrder:invalid';
msg=sprintf('%s\n','Problem found', ...
'No canonical HRF was used to model the data', ...
'Current file will be skipped');
throw(MException(id,msg));
end
if (length(SPM.Sess) > 1 )
id='BSM:CoreCalc:SPMSess:invalid';
msg=sprintf('%s\n',...
'Problem found', ...
'Multiple sessions in one SPM.mat not supported', ...
'Current file will be skipped');
throw(MException(id,msg));
end
% end exception block
%% set local variables
SPMOrig = SPM;
UOrig = SPM.Sess(1).U;
[ActCol,~,~]=obj.GetColDef(UOrig);
LocalTargetFolder = fullfile(fileparts(SpmFile),'BSM');%RR replace BSM by a obj.BSMDir so user can modify this
%% create directory
mkdir(LocalTargetFolder);
% loop over ActCol
for c=1:length(ActCol)
% get current col, get other col
CurCol=ActCol(c);
OthCol=setdiff(1:length(ActCol),CurCol);
TargetFolderCurCol=fullfile(LocalTargetFolder,sprintf('col_%04d', CurCol));
NEvents=numel(UOrig(CurCol).ons);
DirTrialList=cell(NEvents,1);
BetaTrialList=cell(NEvents,1);
for e=1:NEvents% loop over events
U=obj.GetU(UOrig,e,CurCol,OthCol);%build U
DirTrialList{e}=obj.GenSPM(U,SPMOrig,TargetFolderCurCol,e);%build SPM
obj.RunJob(DirTrialList{e});%process SPM
BetaTrialList{e}=spm_select('ExtFPList',DirTrialList{e},'^beta_0001.*.nii$',1);
end% end loop
obj.PackBetas(BetaTrialList,LocalTargetFolder,CurCol)%pack per event result
obj.CleanUp(TargetFolderCurCol);
end % end loop act. col
% restore warning status
warning(WarnStat);
catch ME %turn matlab warning back on
warning(WarnStat);
rethrow(ME);
end
end
function CleanUp(~,D)
if obj.Clean
try
rmdir(D,'s');
catch ME
disp(ME)
id = 'BSM:Clean:Failed';
msg= 'Cleaning failed';
throw(MException(id,msg));
end
end
end
function PackBetas(obj,P,wd,Col)
FPFout=fullfile(wd,sprintf('%s_%04d.nii',obj.Prefix,Col));
matlabbatch{1}.spm.util.cat.vols = P;
matlabbatch{1}.spm.util.cat.name = FPFout;
matlabbatch{1}.spm.util.cat.dtype = 4;
spm_jobman('run', matlabbatch);
end
function RunJob(~,swd)
%% estimate model:
matlabbatch{1}.spm.stats.fmri_est.spmmat = {fullfile(swd,'SPM.mat')};
matlabbatch{1}.spm.stats.fmri_est.method.Classical = 1;
spm_jobman('run', matlabbatch);
end
function swd=GenSPM(obj,U,SPMOrig,TargetFolderCol,Event)
SPM=SPMOrig;
TargetFolderColTrial=fullfile(TargetFolderCol,sprintf('trial_%04d',Event));
mkdir(TargetFolderColTrial);
SPM.swd = TargetFolderColTrial;
SPM.Sess.U=U;
U=spm_get_ons(SPM,1); % to have SPM autocomplete the U structure
[X,~,Fc]=spm_Volterra(U,SPM.xBF.bf,SPM.xBF.Volterra);
k=SPM.nscan(1);
fMRI_T = SPM.xBF.T;
fMRI_T0 = SPM.xBF.T0;
X = X((0:(k-1))*fMRI_T +fMRI_T0 + 32,:);%@JB what does the +32 do?
%orthogonalize
for k=1:numel(Fc)
X(:,Fc(k).i)=spm_orth(X(:,Fc(k).i));
end
Xname=cell(1,size(X,2));
for k = 1:size(X,2)
Xname{k} = [sprintf('Sn(%i) ',1) SPM.Sess(1).U(k).name{1}];
end
%% reinstate motion parameters
if (obj.KeepMP)&& ~isempty(SPMOrig.Sess(1).C.C)
C = SPMOrig.Sess(1).C.C;
Cname = job.SPM_orig.Sess(1).C.name;
X = cat(2,X,spm_detrend(C));
Xname = cat(2,Xname, Cname(:));
end
%% reinstate baseline column
X(:,end+1) = 1;
Xname = cat(2,Xname,{sprintf('Sn(%i) %s',1,'constant')});
%% monitor
if obj.MonitorState
figure(100);
clf;
imagesc(X);
pause(0.5);
end
%% Rebuild SPM
SPM.xX.X = X;
SPM.xX.iB = size(X,2);
SPM.xX.iC = 1:size(X,2)-1;
SPM.xX.name = Xname;
try
SPM.xX = rmfield(SPM.xX,'W');%remove prewhitening matrix
catch
end
save(fullfile(SPM.swd,'SPM.mat'),'SPM');
swd=SPM.swd;
end
function U=GetU(obj,UOrig,Event,Col,OCol)
U=struct('name',{},'ons', [], 'dur', [],'orth', [], 'P', [], 'dt', [], 'u', [],'pst',[]);
idx=1;
%split out current event as first condition
U(idx).name{1} = sprintf('%s_%d',UOrig(Col).name{1},Event);
U(idx).ons = UOrig(Col).ons(Event);
U(idx).dur = UOrig(Col).dur(Event);
U(idx).orth = UOrig(Col).orth;
U(idx).P = UOrig(Col).P;
U(idx).dt = UOrig(Col).dt;
% u
% pst
%optional add all other events as the next condition
switch obj.Type
case {1,2}
idx = idx +1;
OtherTrials=setdiff(1:numel(UOrig(Col).ons),Event);
U(idx).name{1} = sprintf('%s_oe',UOrig(Col).name{1});
U(idx).ons = UOrig(Col).ons(OtherTrials);
U(idx).dur = UOrig(Col).dur(OtherTrials);
U(idx).orth = UOrig(Col).orth;
U(idx).P = UOrig(Col).P;
U(idx).dt = UOrig(Col).dt;
% u
% pst
case {3,4}
otherwise
end
% deal with other conditions
if ~isempty(OCol)
switch obj.Type
case {1,4} %put all other conditions in one column
idx = idx + 1;
U(idx).name{1} = 'AllOtherConditions';
U(idx).ons = cat(1,UOrig(OCol).ons);
for k = OCol
if numel(UOrig(k).dur)==1
dur=repmat(UOrig(k).dur,size(UOrig(k).ons));
elseif numel(UOrig(k).dur)==numel(UOrig(k).ons)
dur=UOrig(k).dur;
else
id='BSM:GetU:InvalidNumberDuration';
msg=sprintf('%s\n'...
,'Number of durations is neither one nor the number of onsets'...
);
throw(MException(id,msg));
end
U(idx).dur=cat(1,U(idx).dur,dur);
U(idx).orth = UOrig(k).orth;
U(idx).P = UOrig(k).P;
U(idx).dt = UOrig(k).dt;
end
case {2,3} %keep other conditions each in their own column
U=cat(2,U,UOrig(OCol));
otherwise
end
%clear out fields u and pst They will be rebuild when SPM
%is created
[U(:).pst]=deal([]);
[U(:).u]=deal([]);
end
end
function [ActCol,PasCol,AllCol]=GetColDef(obj,U)
AllCol=1:length(U);
if ~isempty(obj.Acfl)
PasCol = AllCol(obj.Acfl); %cf line 53 in spm_bsm.m
else
PasCol = [];
end
ActCol = setdiff(AllCol,PasCol);
end
function[val,TF]=MyGetVal(~,selector,List)
TF=strcmpi(selector,List);
if any(TF) %spmpath is set as option
k=find(TF, 1 );%find the first instance
if (k+1)>numel(List)
id='BSM:getval:ReadBeyondEndInput';
msg=sprintf('use name value pairs\nlast entry is a name');
throw(MException(id,msg));
end
val=List{k+1};
TF=true;
else
val=false;
TF=false;
end
end
end
end