AMR/data-raw/eucast_rules.tsv

# -------------------------------------------------------------------------------------------------------------------------------
# For editing this EUCAST reference file, these values can all be used for targeting antibiotics:
# 'all_betalactams', 'aminoglycosides', 'aminopenicillins', 'carbapenems', 'cephalosporins', 'cephalosporins_except_CAZ',
# 'fluoroquinolones', 'glycopeptides', 'macrolides', 'polymyxins', 'streptogramins', 'tetracyclines', 'ureidopenicillins'
# and all separate EARS-Net letter codes like 'AMC'. They can be separated by comma: 'AMC, fluoroquinolones'.
# The 'if_mo_property' column can be any column name from the AMR::microorganisms data set, or "genus_species" or "gramstain".
# The like.is.one_of column must be 'like' or 'is' or 'one_of' ('like' will read the 'this_value' column as regular expression)
# The EUCAST guideline contains references to the 'Burkholderia cepacia complex'. All species in this group are noted on the 'B.cepacia' sheet of the EUCAST Clinical Breakpoint v.10.0 Excel file of 2020 (v_10.0_Breakpoint_Tables.xlsx).
# >>>>> IF YOU WANT TO IMPORT THIS FILE INTO YOUR OWN SOFTWARE, HAVE THE FIRST 10 LINES SKIPPED <<<<<
# -------------------------------------------------------------------------------------------------------------------------------
if_mo_property	like.is.one_of	this_value	and_these_antibiotics	have_these_values	then_change_these_antibiotics	to_value	reference.rule	reference.rule_group	reference.version
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints
genus	is	Staphylococcus	PEN, FOX	S	AMP, AMX, PIP, TIC	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	PEN, FOX	R, S	OXA, FLC	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	R	all_betalactams	R	Staphylococcus	Breakpoints
genus_species	is	Staphylococcus saprophyticus	AMP	S	AMX, AMC, PIP, TZP	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	S	carbapenems, cephalosporins_except_CAZ	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	I	carbapenems, cephalosporins_except_CAZ	I	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	R	carbapenems, cephalosporins_except_CAZ	R	Staphylococcus	Breakpoints
genus	is	Staphylococcus	NOR	S	CIP, LVX, MFX, OFX	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	ERY	S	AZM, CLR, RXT	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	ERY	I	AZM, CLR, RXT	I	Staphylococcus	Breakpoints
genus	is	Staphylococcus	ERY	R	AZM, CLR, RXT	R	Staphylococcus	Breakpoints
genus	is	Staphylococcus	TCY	S	DOX, MNO	S	Staphylococcus	Breakpoints
genus	is	Enterococcus	AMP	S	AMX, AMC, PIP, TZP	S	Enterococcus	Breakpoints
genus	is	Enterococcus	AMP	I	AMX, AMC, PIP, TZP	I	Enterococcus	Breakpoints
genus	is	Enterococcus	AMP	R	AMX, AMC, PIP, TZP	R	Enterococcus	Breakpoints
genus	is	Enterococcus	NOR	S	CIP, LVX	S	Enterococcus	Breakpoints
genus	is	Enterococcus	NOR	I	CIP, LVX	I	Enterococcus	Breakpoints
genus	is	Enterococcus	NOR	R	CIP, LVX	R	Enterococcus	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	PEN	S	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	PEN	I	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	I	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	PEN	R	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	R	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	NOR	S	MFX	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	NOR	S	LVX	I	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	ERY	S	AZM, CLR, RXT	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	ERY	I	AZM, CLR, RXT	I	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	ERY	R	AZM, CLR, RXT	R	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	TCY	S	DOX, MNO	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	is	Streptococcus pneumoniae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	AMP	S	AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	AMP	I	AMX, AMC, PIP, TZP	I	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	AMP	R	AMX, AMC, PIP, TZP	R	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	NOR	S	MFX	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	NOR	S	LVX	I	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	ERY	S	AZM, CLR, RXT	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	ERY	I	AZM, CLR, RXT	I	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	ERY	R	AZM, CLR, RXT	R	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	TCY	S	DOX, MNO	S	Streptococcus pneumoniae	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	AMP	S	AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	AMP	I	AMX, AMC, PIP, TZP	I	Viridans group streptococci	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	AMP	R	AMX, AMC, PIP, TZP	R	Viridans group streptococci	Breakpoints
genus_species	is	Haemophilus influenzae	AMP	S	AMX, PIP	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMP	I	AMX, PIP	I	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMP	R	AMX, PIP	R	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMC	S	TZP	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMC	I	TZP	I	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMC	R	TZP	R	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	NAL	S	CIP, LVX, MFX, OFX	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Haemophilus influenzae	Breakpoints
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	NAL	S	CIP, LVX, MFX, OFX	S	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	ERY	S	AZM, CLR, RXT	S	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	ERY	I	AZM, CLR, RXT	I	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	ERY	R	AZM, CLR, RXT	R	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	TCY	S	DOX, MNO	S	Moraxella catarrhalis	Breakpoints
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	S	AMP, AMX, PIP, TZP, TIC	S	Anaerobic Gram-positives	Breakpoints
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	I	AMP, AMX, PIP, TZP, TIC	I	Anaerobic Gram-positives	Breakpoints
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	R	AMP, AMX, PIP, TZP, TIC	R	Anaerobic Gram-positives	Breakpoints
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	S	AMP, AMX, PIP, TZP, TIC	S	Anaerobic Gram-negatives	Breakpoints
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	I	AMP, AMX, PIP, TZP, TIC	I	Anaerobic Gram-negatives	Breakpoints
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	R	AMP, AMX, PIP, TZP, TIC	R	Anaerobic Gram-negatives	Breakpoints
genus_species	is	Pasteurella multocida	PEN	S	AMP, AMX	S	Pasteurella multocida	Breakpoints
genus_species	is	Pasteurella multocida	PEN	I	AMP, AMX	I	Pasteurella multocida	Breakpoints
genus_species	is	Pasteurella multocida	PEN	R	AMP, AMX	R	Pasteurella multocida	Breakpoints
genus_species	is	Campylobacter coli	ERY	S	AZM, CLR	S	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	ERY	I	AZM, CLR	I	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	ERY	R	AZM, CLR	R	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	TCY	S	DOX	S	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	TCY	I	DOX	I	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	TCY	R	DOX	R	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter jejuni	ERY	S	AZM, CLR	S	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	ERY	I	AZM, CLR	I	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	ERY	R	AZM, CLR	R	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	TCY	S	DOX	S	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	TCY	I	DOX	I	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	TCY	R	DOX	R	Campylobacter jejuni	Breakpoints
genus_species	is	Aerococcus sanguinicola	NOR	S	fluoroquinolones	S	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	NOR	I	fluoroquinolones	I	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	NOR	R	fluoroquinolones	R	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	CIP	S	LVX	S	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	CIP	I	LVX	I	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	CIP	R	LVX	R	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	NOR	S	fluoroquinolones	S	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	NOR	I	fluoroquinolones	I	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	NOR	R	fluoroquinolones	R	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	CIP	S	LVX	S	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	CIP	I	LVX	I	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	CIP	R	LVX	R	Aerococcus urinae	Breakpoints
genus_species	is	Kingella kingae	PEN	S	AMP, AMX	S	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	PEN	I	AMP, AMX	I	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	PEN	R	AMP, AMX	R	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	ERY	S	AZM, CLR	S	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	ERY	I	AZM, CLR	I	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	ERY	R	AZM, CLR	R	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	TCY	I	DOX	I	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	TCY	R	DOX	R	Kingella kingae	Breakpoints
genus_species	is	Burkholderia pseudomallei	TCY	S	DOX	S	Burkholderia pseudomallei	Breakpoints
genus_species	is	Burkholderia pseudomallei	TCY	I	DOX	I	Burkholderia pseudomallei	Breakpoints
genus_species	is	Burkholderia pseudomallei	TCY	R	DOX	R	Burkholderia pseudomallei	Breakpoints
order	is	Enterobacterales			PEN, glycopeptides, FUS, macrolides, LIN, streptogramins, RIF, DAP, LNZ	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
fullname	like	^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
fullname	like	^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Enterobacter cloacae			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Enterobacter aerogenes			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Escherichia hermanni			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Hafnia alvei			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus	is	Klebsiella			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Morganella morganii			aminopenicillins, AMC, CZO, tetracyclines, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Proteus mirabilis			tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Proteus penneri			aminopenicillins, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Proteus vulgaris			aminopenicillins, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Providencia rettgeri			aminopenicillins, AMC, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Providencia stuartii			aminopenicillins, AMC, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus	is	Raoultella			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Serratia marcescens			aminopenicillins, AMC, CZO, FOX, CXM, DOX, TCY, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Yersinia enterocolitica			aminopenicillins, AMC, TIC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus_species	is	Yersinia pseudotuberculosis			PLB, COL	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules
genus	one_of	Achromobacter, Acinetobacter, Alcaligenes, Bordatella, Burkholderia, Elizabethkingia, Flavobacterium, Ochrobactrum, Pseudomonas, Stenotrophomonas			PEN, FOX, CXM, glycopeptides, FUS, macrolides, LIN, streptogramins, RIF, DAP, LNZ	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter baumannii			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter pittii			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter nosocomialis			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter calcoaceticus			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Achromobacter xylosoxidans			aminopenicillins, CZO, CTX, CRO, ETP	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
fullname	like	^Burkholderia (ambifaria|anthina|arboris|cepacia|cenocepacia|contaminans|diffusa|dolosa|lata|latens|metallica|multivorans|paludis|pseudomultivorans|pyrrocinia|pseudomultivorans|seminalis|stabilis|stagnalis|territorii|ubonensis|vietnamiensis)			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, ATM, ETP, CIP, CHL, aminoglycosides, TMP, FOS, polymyxins	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Elizabethkingia meningoseptica			aminopenicillins, AMC, TIC, CZO, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM, polymyxins	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Ochrobactrum anthropi			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, CAZ, FEP, ATM, ETP	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Pseudomonas aeruginosa			aminopenicillins, AMC, CZO, CTX, CRO, ETP, CHL, KAN, NEO, TMP, SXT, tetracyclines, TGC	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Stenotrophomonas maltophilia			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, ATM, ETP, IPM, MEM, aminoglycosides, TMP, FOS, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus	one_of	Haemophilus, Moraxella, Neisseria, Campylobacter			glycopeptides, LIN, DAP, LNZ	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Haemophilus influenzae			FUS, streptogramins	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Moraxella catarrhalis			TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus	is	Neisseria			TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Campylobacter fetus			FUS, streptogramins, TMP, NAL	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Campylobacter jejuni			FUS, streptogramins, TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Campylobacter coli			FUS, streptogramins, TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
gramstain	is	Gram-positive			ATM, polymyxins, NAL	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus saprophyticus			FUS, CAZ, FOS, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus cohnii			CAZ, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus xylosus			CAZ, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus capitis			CAZ, FOS	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus aureus			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus epidermidis			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus coagulase-negative			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus hominis			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus haemolyticus			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus intermedius			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus pseudintermedius			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	is	Streptococcus			FUS, CAZ, aminoglycosides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus faecalis			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus gallinarum			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus casseliflavus			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus faecium			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	is	Corynebacterium			FOS	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Listeria monocytogenes			cephalosporins	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	one_of	Leuconostoc, Pediococcus			glycopeptides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	is	Lactobacillus			glycopeptides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Clostridium ramosum			VAN	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Clostridium innocuum			VAN	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)	PEN	S	aminopenicillins, cephalosporins_except_CAZ, carbapenems	S	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules
genus	is	Enterococcus	AMP	R	ureidopenicillins, carbapenems	R	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules
genus	is	Enterococcus	AMX	R	ureidopenicillins, carbapenems	R	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules
order	is	Enterobacterales	TIC, PIP	R, S	PIP	R	Table 09: Interpretive rules for B-lactam agents and Gram-negative rods (at the time: Enterobacteriaceae)	Expert Rules
genus	like	.*	ERY	S	AZM, CLR	S	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules
genus	like	.*	ERY	I	AZM, CLR	I	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules
genus	like	.*	ERY	R	AZM, CLR	R	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules
genus	is	Staphylococcus	TOB	R	KAN, AMK	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
genus	is	Staphylococcus	GEN	R	aminoglycosides	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
order	is	Enterobacterales	GEN, TOB	I, S	GEN	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
order	is	Enterobacterales	GEN, TOB	R, I	TOB	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
genus	is	Staphylococcus	MFX	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules
genus_species	is	Streptococcus pneumoniae	MFX	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules
order	is	Enterobacterales	CIP	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules
genus_species	is	Neisseria gonorrhoeae	CIP	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules