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# ==================================================================== #
# TITLE #
# Antimicrobial Resistance (AMR) Analysis #
# #
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# SOURCE #
# https://gitlab.com/msberends/AMR #
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# #
# LICENCE #
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# (c) 2018-2020 Berends MS, Luz CF et al. #
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# #
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# This R package is free software; you can freely use and distribute #
# it for both personal and commercial purposes under the terms of the #
# GNU General Public License version 2.0 (GNU GPL-2), as published by #
# the Free Software Foundation. #
# #
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# We created this package for both routine data analysis and academic #
# research and it was publicly released in the hope that it will be #
# useful, but it comes WITHOUT ANY WARRANTY OR LIABILITY. #
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# Visit our website for more info: https://msberends.gitlab.io/AMR. #
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# ==================================================================== #
#' Property of a microorganism
#'
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#' Use these functions to return a specific property of a microorganism. All input values will be evaluated internally with [as.mo()], which makes it possible to use microbial abbreviations, codes and names as input. Please see *Examples*.
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#' @param x any (vector of) text that can be coerced to a valid microorganism code with [as.mo()]
#' @param property one of the column names of the [microorganisms] data set or `"shortname"`
#' @param language language of the returned text, defaults to system language (see [get_locale()]) and can also be set with `getOption("AMR_locale")`. Use `language = NULL` or `language = ""` to prevent translation.
#' @param ... other parameters passed on to [as.mo()]
#' @param open browse the URL using [utils::browseURL()]
#' @details All functions will return the most recently known taxonomic property according to the Catalogue of Life, except for [mo_ref()], [mo_authors()] and [mo_year()]. This leads to the following results:
#' - `mo_name("Chlamydia psittaci")` will return `"Chlamydophila psittaci"` (with a warning about the renaming)
#' - `mo_ref("Chlamydia psittaci")` will return `"Page, 1968"` (with a warning about the renaming)
#' - `mo_ref("Chlamydophila psittaci")` will return `"Everett et al., 1999"` (without a warning)
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#'
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#' The Gram stain - [mo_gramstain()] - will be determined on the taxonomic kingdom and phylum. According to Cavalier-Smith (2002) who defined subkingdoms Negibacteria and Posibacteria, only these phyla are Posibacteria: Actinobacteria, Chloroflexi, Firmicutes and Tenericutes. These bacteria are considered Gram-positive - all other bacteria are considered Gram-negative. Species outside the kingdom of Bacteria will return a value `NA`.
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#'
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#' All output will be [translate]d where possible.
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#'
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#' The function [mo_url()] will return the direct URL to the online database entry, which also shows the scientific reference of the concerned species.
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#' @inheritSection catalogue_of_life Catalogue of Life
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#' @inheritSection as.mo Source
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#' @rdname mo_property
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#' @name mo_property
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#' @return
#' - An [`integer`] in case of [mo_year()]
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#' - A [`list`] in case of [mo_taxonomy()] and [mo_info()]
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#' - A named [`character`] in case of [mo_url()]
#' - A [`character`] in all other cases
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#' @export
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#' @seealso [microorganisms]
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#' @inheritSection AMR Read more on our website!
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#' @examples
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#' # taxonomic tree -----------------------------------------------------------
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#' mo_kingdom("E. coli") # "Bacteria"
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#' mo_phylum("E. coli") # "Proteobacteria"
#' mo_class("E. coli") # "Gammaproteobacteria"
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#' mo_order("E. coli") # "Enterobacterales"
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#' mo_family("E. coli") # "Enterobacteriaceae"
#' mo_genus("E. coli") # "Escherichia"
#' mo_species("E. coli") # "coli"
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#' mo_subspecies("E. coli") # ""
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#'
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#' # colloquial properties ----------------------------------------------------
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#' mo_name("E. coli") # "Escherichia coli"
#' mo_fullname("E. coli") # "Escherichia coli", same as mo_name()
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#' mo_shortname("E. coli") # "E. coli"
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#'
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#' # other properties ---------------------------------------------------------
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#' mo_gramstain("E. coli") # "Gram-negative"
#' mo_type("E. coli") # "Bacteria" (equal to kingdom, but may be translated)
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#' mo_rank("E. coli") # "species"
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#' mo_url("E. coli") # get the direct url to the online database entry
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#' mo_synonyms("E. coli") # get previously accepted taxonomic names
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#'
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#' # scientific reference -----------------------------------------------------
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#' mo_ref("E. coli") # "Castellani et al., 1919"
#' mo_authors("E. coli") # "Castellani et al."
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#' mo_year("E. coli") # 1919
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#'
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#' # abbreviations known in the field -----------------------------------------
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#' mo_genus("MRSA") # "Staphylococcus"
#' mo_species("MRSA") # "aureus"
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#' mo_shortname("VISA") # "S. aureus"
#' mo_gramstain("VISA") # "Gram-positive"
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#'
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#' mo_genus("EHEC") # "Escherichia"
#' mo_species("EHEC") # "coli"
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#'
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#' # known subspecies ---------------------------------------------------------
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#' mo_name("doylei") # "Campylobacter jejuni doylei"
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#' mo_genus("doylei") # "Campylobacter"
#' mo_species("doylei") # "jejuni"
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#' mo_subspecies("doylei") # "doylei"
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#'
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#' mo_fullname("K. pneu rh") # "Klebsiella pneumoniae rhinoscleromatis"
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#' mo_shortname("K. pneu rh") # "K. pneumoniae"
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#'
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#' \donttest{
#' # Becker classification, see ?as.mo ----------------------------------------
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#' mo_fullname("S. epi") # "Staphylococcus epidermidis"
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#' mo_fullname("S. epi", Becker = TRUE) # "Coagulase-negative Staphylococcus (CoNS)"
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#' mo_shortname("S. epi") # "S. epidermidis"
#' mo_shortname("S. epi", Becker = TRUE) # "CoNS"
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#'
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#' # Lancefield classification, see ?as.mo ------------------------------------
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#' mo_fullname("S. pyo") # "Streptococcus pyogenes"
#' mo_fullname("S. pyo", Lancefield = TRUE) # "Streptococcus group A"
#' mo_shortname("S. pyo") # "S. pyogenes"
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#' mo_shortname("S. pyo", Lancefield = TRUE) # "GAS" (='Group A Streptococci')
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#'
#'
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#' # language support for German, Dutch, Spanish, Portuguese, Italian and French
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#' mo_gramstain("E. coli", language = "de") # "Gramnegativ"
#' mo_gramstain("E. coli", language = "nl") # "Gram-negatief"
#' mo_gramstain("E. coli", language = "es") # "Gram negativo"
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#'
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#' # mo_type is equal to mo_kingdom, but mo_kingdom will remain official
#' mo_kingdom("E. coli") # "Bacteria" on a German system
#' mo_type("E. coli") # "Bakterien" on a German system
#' mo_type("E. coli") # "Bacteria" on an English system
#'
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#' mo_fullname("S. pyogenes",
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#' Lancefield = TRUE,
#' language = "de") # "Streptococcus Gruppe A"
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#' mo_fullname("S. pyogenes",
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#' Lancefield = TRUE,
#' language = "nl") # "Streptococcus groep A"
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#'
#'
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#' # get a list with the complete taxonomy (from kingdom to subspecies)
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#' mo_taxonomy("E. coli")
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#' # get a list with the taxonomy, the authors, Gram-stain and URL to the online database
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#' mo_info("E. coli")
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#' }
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mo_name <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " fullname" , ... ) , language = language , only_unknown = FALSE )
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}
#' @rdname mo_property
#' @export
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mo_fullname <- mo_name
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#' @rdname mo_property
#' @export
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mo_shortname <- function ( x , language = get_locale ( ) , ... ) {
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x.mo <- AMR :: as.mo ( x , ... )
metadata <- get_mo_failures_uncertainties_renamed ( )
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replace_empty <- function ( x ) {
x [x == " " ] <- " spp."
x
}
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# get first char of genus and complete species in English
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shortnames <- paste0 ( substr ( mo_genus ( x.mo , language = NULL ) , 1 , 1 ) , " . " , replace_empty ( mo_species ( x.mo , language = NULL ) ) )
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# exceptions for Staphylococci
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shortnames [shortnames == " S. coagulase-negative" ] <- " CoNS"
shortnames [shortnames == " S. coagulase-positive" ] <- " CoPS"
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# exceptions for Streptococci: Streptococcus Group A -> GAS
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shortnames [shortnames %like% " S. group [ABCDFGHK]" ] <- paste0 ( " G" , gsub ( " S. group ([ABCDFGHK])" , " \\1" , shortnames [shortnames %like% " S. group [ABCDFGHK]" ] ) , " S" )
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load_mo_failures_uncertainties_renamed ( metadata )
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translate_AMR ( shortnames , language = language , only_unknown = FALSE )
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}
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#' @rdname mo_property
#' @export
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mo_subspecies <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " subspecies" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_species <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " species" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_genus <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " genus" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_family <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " family" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_order <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " order" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_class <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " class" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_phylum <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " phylum" , ... ) , language = language , only_unknown = TRUE )
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}
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#' @rdname mo_property
#' @export
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mo_kingdom <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " kingdom" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_type <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " kingdom" , ... ) , language = language , only_unknown = FALSE )
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}
#' @rdname mo_property
#' @export
mo_gramstain <- function ( x , language = get_locale ( ) , ... ) {
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x.mo <- AMR :: as.mo ( x , ... )
metadata <- get_mo_failures_uncertainties_renamed ( )
x.phylum <- mo_phylum ( x.mo )
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# DETERMINE GRAM STAIN FOR BACTERIA
# Source: https://itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_value=956097
# It says this:
# Kingdom Bacteria (Cavalier-Smith, 2002)
# Subkingdom Posibacteria (Cavalier-Smith, 2002)
# Direct Children:
# Phylum Actinobacteria (Cavalier-Smith, 2002)
# Phylum Chloroflexi (Garrity and Holt, 2002)
# Phylum Firmicutes (corrig. Gibbons and Murray, 1978)
# Phylum Tenericutes (Murray, 1984)
x <- NA_character_
# make all bacteria Gram negative
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x [mo_kingdom ( x.mo ) == " Bacteria" ] <- " Gram-negative"
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# overwrite these phyla with Gram positive
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x [x.phylum %in% c ( " Actinobacteria" ,
" Chloroflexi" ,
" Firmicutes" ,
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" Tenericutes" )
| x.mo == " B_GRAMP" ] <- " Gram-positive"
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load_mo_failures_uncertainties_renamed ( metadata )
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translate_AMR ( x , language = language , only_unknown = FALSE )
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}
#' @rdname mo_property
#' @export
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mo_ref <- function ( x , ... ) {
mo_validate ( x = x , property = " ref" , ... )
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}
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#' @rdname mo_property
#' @export
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mo_authors <- function ( x , ... ) {
x <- mo_validate ( x = x , property = " ref" , ... )
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# remove last 4 digits and presumably the comma and space that preceed them
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x [ ! is.na ( x ) ] <- gsub ( " ,? ?[0-9]{4}" , " " , x [ ! is.na ( x ) ] )
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suppressWarnings ( x )
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}
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#' @rdname mo_property
#' @export
mo_year <- function ( x , ... ) {
x <- mo_validate ( x = x , property = " ref" , ... )
# get last 4 digits
x [ ! is.na ( x ) ] <- gsub ( " .*([0-9]{4})$" , " \\1" , x [ ! is.na ( x ) ] )
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suppressWarnings ( as.integer ( x ) )
}
#' @rdname mo_property
#' @export
mo_rank <- function ( x , ... ) {
mo_validate ( x = x , property = " rank" , ... )
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}
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#' @rdname mo_property
#' @export
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mo_taxonomy <- function ( x , language = get_locale ( ) , ... ) {
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x <- AMR :: as.mo ( x , ... )
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metadata <- get_mo_failures_uncertainties_renamed ( )
result <- base :: list ( kingdom = AMR :: mo_kingdom ( x , language = language ) ,
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phylum = AMR :: mo_phylum ( x , language = language ) ,
class = AMR :: mo_class ( x , language = language ) ,
order = AMR :: mo_order ( x , language = language ) ,
family = AMR :: mo_family ( x , language = language ) ,
genus = AMR :: mo_genus ( x , language = language ) ,
species = AMR :: mo_species ( x , language = language ) ,
subspecies = AMR :: mo_subspecies ( x , language = language ) )
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load_mo_failures_uncertainties_renamed ( metadata )
result
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}
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#' @rdname mo_property
#' @export
mo_synonyms <- function ( x , ... ) {
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x <- AMR :: as.mo ( x , ... )
metadata <- get_mo_failures_uncertainties_renamed ( )
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IDs <- AMR :: mo_property ( x = x , property = " col_id" , language = NULL )
syns <- lapply ( IDs , function ( col_id ) {
res <- sort ( AMR :: microorganisms.old [which ( AMR :: microorganisms.old $ col_id_new == col_id ) , " fullname" ] )
if ( length ( res ) == 0 ) {
NULL
} else {
res
}
} )
if ( length ( syns ) > 1 ) {
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names ( syns ) <- mo_name ( x )
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result <- syns
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} else {
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result <- unlist ( syns )
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}
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load_mo_failures_uncertainties_renamed ( metadata )
result
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}
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#' @rdname mo_property
#' @export
mo_info <- function ( x , language = get_locale ( ) , ... ) {
x <- AMR :: as.mo ( x , ... )
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metadata <- get_mo_failures_uncertainties_renamed ( )
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info <- lapply ( x , function ( y )
c ( mo_taxonomy ( y , language = language ) ,
list ( synonyms = mo_synonyms ( y ) ,
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gramstain = mo_gramstain ( y , language = language ) ,
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url = unname ( mo_url ( y , open = FALSE ) ) ,
ref = mo_ref ( y ) ) ) )
if ( length ( info ) > 1 ) {
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names ( info ) <- mo_name ( x )
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result <- info
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} else {
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result <- info [ [1L ] ]
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}
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load_mo_failures_uncertainties_renamed ( metadata )
result
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}
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#' @rdname mo_property
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#' @importFrom utils browseURL
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#' @importFrom dplyr %>% left_join select mutate case_when
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#' @export
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mo_url <- function ( x , open = FALSE , ... ) {
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mo <- AMR :: as.mo ( x = x , ... = ... )
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mo_names <- AMR :: mo_name ( mo )
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metadata <- get_mo_failures_uncertainties_renamed ( )
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df <- data.frame ( mo , stringsAsFactors = FALSE ) %>%
left_join ( select ( AMR :: microorganisms , mo , source , species_id ) , by = " mo" ) %>%
mutate ( url = case_when ( source == " CoL" ~
paste0 ( gsub ( " {year}" , catalogue_of_life $ year , catalogue_of_life $ url_CoL , fixed = TRUE ) , " details/species/id/" , species_id ) ,
source == " DSMZ" ~
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paste0 ( catalogue_of_life $ url_DSMZ , " /" , unlist ( lapply ( strsplit ( mo_names , " " ) , function ( x ) x [1 ] ) ) ) ,
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TRUE ~
NA_character_ ) )
u <- df $ url
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names ( u ) <- mo_names
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if ( open == TRUE ) {
if ( length ( u ) > 1 ) {
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warning ( " only the first URL will be opened, as `browseURL()` only suports one string." )
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}
browseURL ( u [1L ] )
}
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load_mo_failures_uncertainties_renamed ( metadata )
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u
}
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#' @rdname mo_property
#' @importFrom data.table data.table as.data.table setkey
#' @export
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mo_property <- function ( x , property = " fullname" , language = get_locale ( ) , ... ) {
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if ( length ( property ) != 1L ) {
stop ( " 'property' must be of length 1." )
}
if ( ! property %in% colnames ( AMR :: microorganisms ) ) {
stop ( " invalid property: '" , property , " ' - use a column name of the `microorganisms` data set" )
}
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translate_AMR ( mo_validate ( x = x , property = property , ... ) , language = language , only_unknown = TRUE )
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}
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mo_validate <- function ( x , property , ... ) {
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load_AMR_package ( )
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dots <- list ( ... )
Becker <- dots $ Becker
if ( is.null ( Becker ) ) {
Becker <- FALSE
}
Lancefield <- dots $ Lancefield
if ( is.null ( Lancefield ) ) {
Lancefield <- FALSE
}
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# try to catch an error when inputting an invalid parameter
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# so the 'call.' can be set to FALSE
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tryCatch ( x [1L ] %in% AMR :: microorganisms [1 , property ] ,
error = function ( e ) stop ( e $ message , call. = FALSE ) )
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if ( is.mo ( x )
& ! Becker %in% c ( TRUE , " all" )
& ! Lancefield %in% c ( TRUE , " all" ) ) {
# this will not reset mo_uncertainties and mo_failures
# because it's already a valid MO
x <- exec_as.mo ( x , property = property , initial_search = FALSE , ... )
} else if ( ! all ( x %in% pull ( AMR :: microorganisms , property ) )
| Becker %in% c ( TRUE , " all" )
| Lancefield %in% c ( TRUE , " all" ) ) {
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x <- exec_as.mo ( x , property = property , ... )
}
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if ( property == " mo" ) {
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return ( to_class_mo ( x ) )
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} else if ( property == " col_id" ) {
return ( as.integer ( x ) )
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} else {
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return ( x )
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}
}