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# ==================================================================== #
# TITLE #
# Antimicrobial Resistance (AMR) Analysis #
# #
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# SOURCE #
# https://gitlab.com/msberends/AMR #
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# #
# LICENCE #
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# (c) 2019 Berends MS (m.s.berends@umcg.nl), Luz CF (c.f.luz@umcg.nl) #
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# #
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# This R package is free software; you can freely use and distribute #
# it for both personal and commercial purposes under the terms of the #
# GNU General Public License version 2.0 (GNU GPL-2), as published by #
# the Free Software Foundation. #
# #
# This R package was created for academic research and was publicly #
# released in the hope that it will be useful, but it comes WITHOUT #
# ANY WARRANTY OR LIABILITY. #
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# Visit our website for more info: https://msberends.gitlab.io/AMR. #
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# ==================================================================== #
#' Property of a microorganism
#'
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#' Use these functions to return a specific property of a microorganism from the \code{\link{microorganisms}} data set. All input values will be evaluated internally with \code{\link{as.mo}}.
#' @param x any (vector of) text that can be coerced to a valid microorganism code with \code{\link{as.mo}}
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#' @param property one of the column names of the \code{\link{microorganisms}} data set or \code{"shortname"}
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#' @param language language of the returned text, defaults to system language (see \code{\link{get_locale}}) and can also be set with \code{\link{getOption}("AMR_locale")}. Use \code{language = NULL} or \code{language = ""} to prevent translation.
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#' @param ... other parameters passed on to \code{\link{as.mo}}
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#' @param open browse the URL using \code{\link[utils]{browseURL}()}
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#' @details All functions will return the most recently known taxonomic property according to the Catalogue of Life, except for \code{mo_ref}, \code{mo_authors} and \code{mo_year}. This leads to the following results:
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#' \itemize{
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#' \item{\code{mo_name("Chlamydia psittaci")} will return \code{"Chlamydophila psittaci"} (with a warning about the renaming)}
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#' \item{\code{mo_ref("Chlamydia psittaci")} will return \code{"Page, 1968"} (with a warning about the renaming)}
#' \item{\code{mo_ref("Chlamydophila psittaci")} will return \code{"Everett et al., 1999"} (without a warning)}
#' }
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#'
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#' The Gram stain - \code{mo_gramstain()} - will be determined on the taxonomic kingdom and phylum. According to Cavalier-Smith (2002) who defined subkingdoms Negibacteria and Posibacteria, only these phyla are Posibacteria: Actinobacteria, Chloroflexi, Firmicutes and Tenericutes. These bacteria are considered Gram positive - all other bacteria are considered Gram negative. Species outside the kingdom of Bacteria will return a value \code{NA}.
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#'
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#' All output will be \link{translate}d where possible.
#'
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#' The function \code{mo_url()} will return the direct URL to the online database entry, which also shows the scientific reference of the concerned species.
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#' @inheritSection catalogue_of_life Catalogue of Life
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#' @inheritSection as.mo Source
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#' @rdname mo_property
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#' @name mo_property
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#' @return \itemize{
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#' \item{An \code{integer} in case of \code{mo_year}}
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#' \item{A \code{list} in case of \code{mo_taxonomy}}
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#' \item{A named \code{character} in case of \code{mo_url}}
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#' \item{A \code{character} in all other cases}
#' }
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#' @export
#' @seealso \code{\link{microorganisms}}
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#' @inheritSection AMR Read more on our website!
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#' @examples
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#' ## taxonomic tree
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#' mo_kingdom("E. coli") # "Bacteria"
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#' mo_phylum("E. coli") # "Proteobacteria"
#' mo_class("E. coli") # "Gammaproteobacteria"
#' mo_order("E. coli") # "Enterobacteriales"
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#' mo_family("E. coli") # "Enterobacteriaceae"
#' mo_genus("E. coli") # "Escherichia"
#' mo_species("E. coli") # "coli"
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#' mo_subspecies("E. coli") # ""
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#'
#' ## colloquial properties
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#' mo_name("E. coli") # "Escherichia coli"
#' mo_fullname("E. coli") # "Escherichia coli", same as mo_name()
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#' mo_shortname("E. coli") # "E. coli"
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#'
#' ## other properties
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#' mo_gramstain("E. coli") # "Gram-negative"
#' mo_type("E. coli") # "Bacteria" (equal to kingdom, but may be translated)
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#' mo_rank("E. coli") # "species"
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#' mo_url("E. coli") # get the direct url to the online database entry
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#' mo_synonyms("E. coli") # get previously accepted taxonomic names
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#'
#' ## scientific reference
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#' mo_ref("E. coli") # "Castellani et al., 1919"
#' mo_authors("E. coli") # "Castellani et al."
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#' mo_year("E. coli") # 1919
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#'
#'
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#' # Abbreviations known in the field
#' mo_genus("MRSA") # "Staphylococcus"
#' mo_species("MRSA") # "aureus"
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#' mo_shortname("MRSA") # "S. aureus"
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#' mo_gramstain("MRSA") # "Gram-positive"
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#'
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#' mo_genus("VISA") # "Staphylococcus"
#' mo_species("VISA") # "aureus"
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#'
#'
#' # Known subspecies
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#' mo_name("doylei") # "Campylobacter jejuni doylei"
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#' mo_genus("doylei") # "Campylobacter"
#' mo_species("doylei") # "jejuni"
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#' mo_subspecies("doylei") # "doylei"
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#'
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#' mo_fullname("K. pneu rh") # "Klebsiella pneumoniae rhinoscleromatis"
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#' mo_shortname("K. pneu rh") # "K. pneumoniae"
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#'
#'
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#' # Becker classification, see ?as.mo
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#' mo_fullname("S. epi") # "Staphylococcus epidermidis"
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#' mo_fullname("S. epi", Becker = TRUE) # "Coagulase-negative Staphylococcus (CoNS)"
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#' mo_shortname("S. epi") # "S. epidermidis"
#' mo_shortname("S. epi", Becker = TRUE) # "CoNS"
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#'
#' # Lancefield classification, see ?as.mo
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#' mo_fullname("S. pyo") # "Streptococcus pyogenes"
#' mo_fullname("S. pyo", Lancefield = TRUE) # "Streptococcus group A"
#' mo_shortname("S. pyo") # "S. pyogenes"
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#' mo_shortname("S. pyo", Lancefield = TRUE) # "GAS" ('Group A streptococci')
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#'
#'
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#' # language support for German, Dutch, Spanish, Portuguese, Italian and French
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#' mo_gramstain("E. coli", language = "de") # "Gramnegativ"
#' mo_gramstain("E. coli", language = "nl") # "Gram-negatief"
#' mo_gramstain("E. coli", language = "es") # "Gram negativo"
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#'
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#' # mo_type is equal to mo_kingdom, but mo_kingdom will remain official
#' mo_kingdom("E. coli") # "Bacteria" on a German system
#' mo_type("E. coli") # "Bakterien" on a German system
#' mo_type("E. coli") # "Bacteria" on an English system
#'
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#' mo_fullname("S. pyogenes",
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#' Lancefield = TRUE,
#' language = "de") # "Streptococcus Gruppe A"
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#' mo_fullname("S. pyogenes",
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#' Lancefield = TRUE,
#' language = "nl") # "Streptococcus groep A"
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#'
#'
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#' # get a list with the complete taxonomy (from kingdom to subspecies)
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#' mo_taxonomy("E. coli")
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#' # get a list with the taxonomy, the authors and the URL to the online database
#' mo_info("E. coli")
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mo_name <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " fullname" , ... ) , language = language , only_unknown = FALSE )
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}
#' @rdname mo_property
#' @export
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mo_fullname <- mo_name
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#' @rdname mo_property
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#' @importFrom dplyr %>% mutate pull
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#' @export
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mo_shortname <- function ( x , language = get_locale ( ) , ... ) {
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dots <- list ( ... )
Becker <- dots $ Becker
if ( is.null ( Becker ) ) {
Becker <- FALSE
}
Lancefield <- dots $ Lancefield
if ( is.null ( Lancefield ) ) {
Lancefield <- FALSE
}
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# get result without transformations
res1 <- AMR :: as.mo ( x , Becker = FALSE , Lancefield = FALSE , reference_df = dots $ reference_df )
# and result with transformations
res2 <- suppressWarnings ( AMR :: as.mo ( res1 , ... ) )
res2_fullname <- mo_fullname ( res2 , language = language )
res2_fullname [res2_fullname %like% " \\(CoNS\\)" ] <- " CoNS"
res2_fullname [res2_fullname %like% " \\(CoPS\\)" ] <- " CoPS"
res2_fullname [res2_fullname %like% " \\(KNS\\)" ] <- " KNS"
res2_fullname [res2_fullname %like% " \\(KPS\\)" ] <- " KPS"
res2_fullname [res2_fullname %like% " \\(CNS\\)" ] <- " CNS"
res2_fullname [res2_fullname %like% " \\(CPS\\)" ] <- " CPS"
res2_fullname [res2_fullname %like% " \\(SCN\\)" ] <- " SCN"
res2_fullname <- gsub ( " Streptococcus (group|Gruppe|gruppe|groep|grupo|gruppo|groupe) (.)" ,
" G\\2S" ,
res2_fullname ) # turn "Streptococcus group A" and "Streptococcus grupo A" to "GAS"
res2_fullname_vector <- res2_fullname [res2_fullname == mo_fullname ( res1 ) ]
res2_fullname [res2_fullname == mo_fullname ( res1 ) ] <- paste0 ( substr ( mo_genus ( res2_fullname_vector ) , 1 , 1 ) ,
" . " ,
suppressWarnings ( mo_species ( res2_fullname_vector ) ) )
if ( sum ( res1 == res2 , na.rm = TRUE ) > 0 ) {
res1 [res1 == res2 ] <- paste0 ( substr ( mo_genus ( res1 [res1 == res2 ] ) , 1 , 1 ) ,
" . " ,
suppressWarnings ( mo_species ( res1 [res1 == res2 ] ) ) )
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}
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res1 [res1 != res2 ] <- res2_fullname
result <- as.character ( res1 )
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translate_AMR ( result , language = language , only_unknown = FALSE )
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}
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#' @rdname mo_property
#' @export
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mo_subspecies <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " subspecies" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_species <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " species" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_genus <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " genus" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_family <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " family" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_order <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " order" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_class <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " class" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_phylum <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " phylum" , ... ) , language = language , only_unknown = TRUE )
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}
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#' @rdname mo_property
#' @export
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mo_kingdom <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " kingdom" , ... ) , language = language , only_unknown = TRUE )
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}
#' @rdname mo_property
#' @export
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mo_type <- function ( x , language = get_locale ( ) , ... ) {
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translate_AMR ( mo_validate ( x = x , property = " kingdom" , ... ) , language = language , only_unknown = FALSE )
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}
#' @rdname mo_property
#' @export
mo_gramstain <- function ( x , language = get_locale ( ) , ... ) {
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x.mo <- as.mo ( x , ... )
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x.phylum <- mo_phylum ( x.mo , language = " en" )
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# DETERMINE GRAM STAIN FOR BACTERIA
# Source: https://itis.gov/servlet/SingleRpt/SingleRpt?search_topic=TSN&search_value=956097
# It says this:
# Kingdom Bacteria (Cavalier-Smith, 2002)
# Subkingdom Posibacteria (Cavalier-Smith, 2002)
# Direct Children:
# Phylum Actinobacteria (Cavalier-Smith, 2002)
# Phylum Chloroflexi (Garrity and Holt, 2002)
# Phylum Firmicutes (corrig. Gibbons and Murray, 1978)
# Phylum Tenericutes (Murray, 1984)
x <- NA_character_
# make all bacteria Gram negative
x [mo_kingdom ( x.mo , language = " en" ) == " Bacteria" ] <- " Gram-negative"
# overwrite these phyla with Gram positive
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x [x.phylum %in% c ( " Actinobacteria" ,
" Chloroflexi" ,
" Firmicutes" ,
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" Tenericutes" )
| x.mo == " B_GRAMP" ] <- " Gram-positive"
translate_AMR ( x , language = language , only_unknown = FALSE )
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}
#' @rdname mo_property
#' @export
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mo_ref <- function ( x , ... ) {
mo_validate ( x = x , property = " ref" , ... )
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}
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#' @rdname mo_property
#' @export
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mo_authors <- function ( x , ... ) {
x <- mo_validate ( x = x , property = " ref" , ... )
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# remove last 4 digits and presumably the comma and space that preceeds them
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x [ ! is.na ( x ) ] <- gsub ( " ,? ?[0-9]{4}" , " " , x [ ! is.na ( x ) ] )
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suppressWarnings ( x )
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}
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#' @rdname mo_property
#' @export
mo_year <- function ( x , ... ) {
x <- mo_validate ( x = x , property = " ref" , ... )
# get last 4 digits
x [ ! is.na ( x ) ] <- gsub ( " .*([0-9]{4})$" , " \\1" , x [ ! is.na ( x ) ] )
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suppressWarnings ( as.integer ( x ) )
}
#' @rdname mo_property
#' @export
mo_rank <- function ( x , ... ) {
mo_validate ( x = x , property = " rank" , ... )
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}
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#' @rdname mo_property
#' @export
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mo_taxonomy <- function ( x , language = get_locale ( ) , ... ) {
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x <- AMR :: as.mo ( x , ... )
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base :: list ( kingdom = mo_kingdom ( x , language = language ) ,
phylum = mo_phylum ( x , language = language ) ,
class = mo_class ( x , language = language ) ,
order = mo_order ( x , language = language ) ,
family = mo_family ( x , language = language ) ,
genus = mo_genus ( x , language = language ) ,
species = mo_species ( x , language = language ) ,
subspecies = mo_subspecies ( x , language = language ) )
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}
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#' @rdname mo_property
#' @export
mo_synonyms <- function ( x , ... ) {
x <- AMR :: as.mo ( x , ... )
col_id <- AMR :: microorganisms [which ( AMR :: microorganisms $ mo == x ) , " col_id" ]
if ( is.na ( col_id ) | ! col_id %in% AMR :: microorganisms.old $ col_id_new ) {
return ( NULL )
}
sort ( AMR :: microorganisms.old [which ( AMR :: microorganisms.old $ col_id_new == col_id ) , " fullname" ] )
}
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#' @rdname mo_property
#' @export
mo_info <- function ( x , language = get_locale ( ) , ... ) {
x <- AMR :: as.mo ( x , ... )
c ( mo_taxonomy ( x , language = language ) ,
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list ( synonyms = mo_synonyms ( x ) ,
url = unname ( mo_url ( x , open = FALSE ) ) ,
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ref = mo_ref ( x ) ) )
}
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#' @rdname mo_property
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#' @importFrom utils browseURL
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#' @importFrom dplyr %>% left_join select mutate case_when
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#' @export
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mo_url <- function ( x , open = FALSE , ... ) {
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mo <- AMR :: as.mo ( x = x , ... = ... )
df <- data.frame ( mo , stringsAsFactors = FALSE ) %>%
left_join ( select ( AMR :: microorganisms , mo , source , species_id ) , by = " mo" ) %>%
mutate ( url = case_when ( source == " CoL" ~
paste0 ( gsub ( " {year}" , catalogue_of_life $ year , catalogue_of_life $ url_CoL , fixed = TRUE ) , " details/species/id/" , species_id ) ,
source == " DSMZ" ~
paste0 ( catalogue_of_life $ url_DSMZ , " ?bnu_no=" , species_id , " #" , species_id ) ,
TRUE ~
NA_character_ ) )
u <- df $ url
names ( u ) <- mo_fullname ( mo )
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if ( open == TRUE ) {
if ( length ( u ) > 1 ) {
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warning ( " only the first URL will be opened, as `browseURL()` only suports one string." )
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}
browseURL ( u [1L ] )
}
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u
}
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#' @rdname mo_property
#' @importFrom data.table data.table as.data.table setkey
#' @export
mo_property <- function ( x , property = ' fullname' , language = get_locale ( ) , ... ) {
if ( length ( property ) != 1L ) {
stop ( " 'property' must be of length 1." )
}
if ( ! property %in% colnames ( AMR :: microorganisms ) ) {
stop ( " invalid property: '" , property , " ' - use a column name of the `microorganisms` data set" )
}
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translate_AMR ( mo_validate ( x = x , property = property , ... ) , language = language , only_unknown = TRUE )
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}
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mo_validate <- function ( x , property , ... ) {
dots <- list ( ... )
Becker <- dots $ Becker
if ( is.null ( Becker ) ) {
Becker <- FALSE
}
Lancefield <- dots $ Lancefield
if ( is.null ( Lancefield ) ) {
Lancefield <- FALSE
}
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if ( ! " AMR" %in% base :: .packages ( ) ) {
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require ( " AMR" )
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# check onLoad() in R/zzz.R: data tables are created there.
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}
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# try to catch an error when inputting an invalid parameter
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# so the 'call.' can be set to FALSE
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tryCatch ( x [1L ] %in% AMR :: microorganisms [1 , property ] ,
error = function ( e ) stop ( e $ message , call. = FALSE ) )
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if ( ! all ( x %in% pull ( AMR :: microorganisms , property ) )
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| Becker %in% c ( TRUE , " all" )
| Lancefield %in% c ( TRUE , " all" ) ) {
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exec_as.mo ( x , property = property , ... )
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} else {
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if ( property == " mo" ) {
return ( structure ( x , class = " mo" ) )
} else {
return ( x )
}
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}
}