AMR/data-raw/eucast_rules.tsv

# -------------------------------------------------------------------------------------------------------------------------------
# For editing this EUCAST reference file, these values can all be used for target antibiotics:
# 'all_betalactams', 'aminoglycosides', 'aminopenicillins', 'carbapenems', 'cephalosporins', 'cephalosporins_except_CAZ',
# 'fluoroquinolones', 'glycopeptides', 'macrolides', 'polymyxins', 'streptogramins', 'tetracyclines', 'ureidopenicillins'
# and all separate EARS-Net letter codes like 'AMC'. They can be separated by comma: 'AMC, fluoroquinolones'.
# The 'if_mo_property' column can be any column name from the AMR::microorganisms data set, or "genus_species" or "gramstain".
# The like.is.one_of column must be 'like' or 'is' or 'one_of' ('like' will read the 'this_value' column as regular expression)
# The EUCAST guideline contains references to the 'Burkholderia cepacia complex'. All species in this group can be found in: LiPuma J (2005, PMID 16217180).
# >>>>> IF YOU WANT TO IMPORT THIS FILE INTO YOUR OWN SOFTWARE, HAVE THE FIRST 10 LINES SKIPPED <<<<<
# -------------------------------------------------------------------------------------------------------------------------------
if_mo_property	like.is.one_of	this_value	and_these_antibiotics	have_these_values	then_change_these_antibiotics	to_value	reference.rule	reference.rule_group
genus	like	.*	AMP	S	AMX	S	Non-EUCAST: inherit ampicillin results for unavailable amoxicillin	Other rules
genus	like	.*	AMP	I	AMX	I	Non-EUCAST: inherit ampicillin results for unavailable amoxicillin	Other rules
genus	like	.*	AMP	R	AMX	R	Non-EUCAST: inherit ampicillin results for unavailable amoxicillin	Other rules
genus	like	.*	AMX	S	AMP	S	Non-EUCAST: inherit amoxicillin results for unavailable ampicillin	Other rules
genus	like	.*	AMX	I	AMP	I	Non-EUCAST: inherit amoxicillin results for unavailable ampicillin	Other rules
genus	like	.*	AMX	R	AMP	R	Non-EUCAST: inherit amoxicillin results for unavailable ampicillin	Other rules
genus	like	.*	AMC	R	AMP, AMX	R	Non-EUCAST: set ampicillin = R where amoxicillin/clav acid = R	Other rules
genus	like	.*	TZP	R	PIP	R	Non-EUCAST: set piperacillin = R where piperacillin/tazobactam = R	Other rules
genus	like	.*	SXT	R	TMP	R	Non-EUCAST: set trimethoprim = R where trimethoprim/sulfa = R	Other rules
genus	like	.*	AMP	S	AMC	S	Non-EUCAST: set amoxicillin/clav acid = S where ampicillin = S	Other rules
genus	like	.*	AMX	S	AMC	S	Non-EUCAST: set amoxicillin/clav acid = S where ampicillin = S	Other rules
genus	like	.*	PIP	S	TZP	S	Non-EUCAST: set piperacillin/tazobactam = S where piperacillin = S	Other rules
genus	like	.*	TMP	S	SXT	S	Non-EUCAST: set trimethoprim/sulfa = S where trimethoprim = S	Other rules
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints
genus	is	Staphylococcus	PEN, FOX	S	AMP, AMX, PIP, TIC	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	PEN, FOX	R, S	OXA, FLC	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	R	all_betalactams	R	Staphylococcus	Breakpoints
genus_species	is	Staphylococcus saprophyticus	AMP	S	AMX, AMC, PIP, TZP	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	S	carbapenems, cephalosporins_except_CAZ	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	I	carbapenems, cephalosporins_except_CAZ	I	Staphylococcus	Breakpoints
genus	is	Staphylococcus	FOX	R	carbapenems, cephalosporins_except_CAZ	R	Staphylococcus	Breakpoints
genus	is	Staphylococcus	NOR	S	CIP, LVX, MFX, OFX	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	ERY	S	AZM, CLR, RXT	S	Staphylococcus	Breakpoints
genus	is	Staphylococcus	ERY	I	AZM, CLR, RXT	I	Staphylococcus	Breakpoints
genus	is	Staphylococcus	ERY	R	AZM, CLR, RXT	R	Staphylococcus	Breakpoints
genus	is	Staphylococcus	TCY	S	DOX, MNO	S	Staphylococcus	Breakpoints
genus_species	is	Enterococcus faecium	AMP	R	all_betalactams	R	Enterococcus	Breakpoints
genus	is	Enterococcus	AMP	S	AMX, AMC, PIP, TZP	S	Enterococcus	Breakpoints
genus	is	Enterococcus	AMP	I	AMX, AMC, PIP, TZP	I	Enterococcus	Breakpoints
genus	is	Enterococcus	AMP	R	AMX, AMC, PIP, TZP	R	Enterococcus	Breakpoints
genus	is	Enterococcus	NOR	S	CIP, LVX	S	Enterococcus	Breakpoints
genus	is	Enterococcus	NOR	I	CIP, LVX	I	Enterococcus	Breakpoints
genus	is	Enterococcus	NOR	R	CIP, LVX	R	Enterococcus	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	PEN	S	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	PEN	I	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	I	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	PEN	R	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	R	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	NOR	S	LVX, MFX	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	ERY	S	AZM, CLR, RXT	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	ERY	I	AZM, CLR, RXT	I	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	ERY	R	AZM, CLR, RXT	R	Streptococcus groups A, B, C, G	Breakpoints
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)$	TCY	S	DOX, MNO	S	Streptococcus groups A, B, C, G	Breakpoints
genus_species	is	Streptococcus pneumoniae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	AMP	S	AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	AMP	I	AMX, AMC, PIP, TZP	I	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	AMP	R	AMX, AMC, PIP, TZP	R	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	NOR	S	LVX, MFX	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	ERY	S	AZM, CLR, RXT	S	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	ERY	I	AZM, CLR, RXT	I	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	ERY	R	AZM, CLR, RXT	R	Streptococcus pneumoniae	Breakpoints
genus_species	is	Streptococcus pneumoniae	TCY	S	DOX, MNO	S	Streptococcus pneumoniae	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	AMP	S	AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	AMP	I	AMX, AMC, PIP, TZP	I	Viridans group streptococci	Breakpoints
genus_species	like	^Streptococcus (australis|bovis|constellatus|cristatus|gallolyticus|gordonii|infantarius|infantis|mitis|mutans|oligofermentans|oralis|peroris|pseudopneumoniae|salivarius|sinensis|sobrinus|thermophilus|vestibularis|anginosus|equinus|intermedius|parasanguinis|sanguinis)$	AMP	R	AMX, AMC, PIP, TZP	R	Viridans group streptococci	Breakpoints
genus_species	is	Haemophilus influenzae	AMP	S	AMX, PIP	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMP	I	AMX, PIP	I	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMP	R	AMX, PIP	R	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMC	S	TZP	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMC	I	TZP	I	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	AMC	R	TZP	R	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	NAL	S	CIP, LVX, MFX, OFX	S	Haemophilus influenzae	Breakpoints
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Haemophilus influenzae	Breakpoints
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	NAL	S	CIP, LVX, MFX, OFX	S	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	ERY	S	AZM, CLR, RXT	S	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	ERY	I	AZM, CLR, RXT	I	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	ERY	R	AZM, CLR, RXT	R	Moraxella catarrhalis	Breakpoints
genus_species	is	Moraxella catarrhalis	TCY	S	DOX, MNO	S	Moraxella catarrhalis	Breakpoints
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	S	AMP, AMX, PIP, TZP, TIC	S	Anaerobic Gram-positives	Breakpoints
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	I	AMP, AMX, PIP, TZP, TIC	I	Anaerobic Gram-positives	Breakpoints
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	R	AMP, AMX, PIP, TZP, TIC	R	Anaerobic Gram-positives	Breakpoints
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	S	AMP, AMX, PIP, TZP, TIC	S	Anaerobic Gram-negatives	Breakpoints
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	I	AMP, AMX, PIP, TZP, TIC	I	Anaerobic Gram-negatives	Breakpoints
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	R	AMP, AMX, PIP, TZP, TIC	R	Anaerobic Gram-negatives	Breakpoints
genus_species	is	Pasteurella multocida	PEN	S	AMP, AMX	S	Pasteurella multocida	Breakpoints
genus_species	is	Pasteurella multocida	PEN	I	AMP, AMX	I	Pasteurella multocida	Breakpoints
genus_species	is	Pasteurella multocida	PEN	R	AMP, AMX	R	Pasteurella multocida	Breakpoints
genus_species	is	Campylobacter coli	ERY	S	AZM, CLR	S	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	ERY	I	AZM, CLR	I	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	ERY	R	AZM, CLR	R	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	TCY	S	DOX	S	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	TCY	I	DOX	I	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter coli	TCY	R	DOX	R	Campylobacter coli	Breakpoints
genus_species	is	Campylobacter jejuni	ERY	S	AZM, CLR	S	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	ERY	I	AZM, CLR	I	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	ERY	R	AZM, CLR	R	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	TCY	S	DOX	S	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	TCY	I	DOX	I	Campylobacter jejuni	Breakpoints
genus_species	is	Campylobacter jejuni	TCY	R	DOX	R	Campylobacter jejuni	Breakpoints
genus_species	is	Aerococcus sanguinicola	NOR	S	fluoroquinolones	S	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	NOR	I	fluoroquinolones	I	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	NOR	R	fluoroquinolones	R	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	CIP	S	LVX	S	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	CIP	I	LVX	I	Aerococcus sanguinicola	Breakpoints
genus_species	is	Aerococcus sanguinicola	CIP	R	LVX	R	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	NOR	S	fluoroquinolones	S	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	NOR	I	fluoroquinolones	I	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	NOR	R	fluoroquinolones	R	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	CIP	S	LVX	S	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	CIP	I	LVX	I	Aerococcus urinae	Breakpoints
genus_species	is	Aerococcus urinae	CIP	R	LVX	R	Aerococcus urinae	Breakpoints
genus_species	is	Kingella kingae	PEN	S	AMP, AMX	S	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	PEN	I	AMP, AMX	I	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	PEN	R	AMP, AMX	R	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	ERY	S	AZM, CLR	S	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	ERY	I	AZM, CLR	I	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	ERY	R	AZM, CLR	R	Kingella kingae	Breakpoints
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints
order	is	Enterobacterales			PEN, glycopeptides, FUS, macrolides, LIN, streptogramins, RIF, DAP, LNZ	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
fullname	like	^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
fullname	like	^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Enterobacter cloacae			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Enterobacter aerogenes			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Escherichia hermanni			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Hafnia alvei			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus	is	Klebsiella			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Morganella morganii			aminopenicillins, AMC, CZO, tetracyclines, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Proteus mirabilis			tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Proteus penneri			aminopenicillins, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Proteus vulgaris			aminopenicillins, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Providencia rettgeri			aminopenicillins, AMC, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Providencia stuartii			aminopenicillins, AMC, CZO, CXM, tetracyclines, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus	is	Raoultella			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Serratia marcescens			aminopenicillins, AMC, CZO, FOX, CXM, DOX, TCY, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Yersinia enterocolitica			aminopenicillins, AMC, TIC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus_species	is	Yersinia pseudotuberculosis			PLB, COL	R	Table 01: Intrinsic resistance in Enterobacteriaceae	Expert Rules
genus	one_of	Achromobacter, Acinetobacter, Alcaligenes, Bordatella, Burkholderia, Elizabethkingia, Flavobacterium, Ochrobactrum, Pseudomonas, Stenotrophomonas			PEN, FOX, CXM, glycopeptides, FUS, macrolides, LIN, streptogramins, RIF, DAP, LNZ	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter baumannii			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter pittii			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter nosocomialis			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Acinetobacter calcoaceticus			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Achromobacter xylosoxidans			aminopenicillins, CZO, CTX, CRO, ETP	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
fullname	like	^Burkholderia (cepacia|multivorans|cenocepacia|stabilis|vietnamiensis|dolosa|ambifaria|anthina|pyrrocinia|ubonensis)			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, ATM, ETP, CIP, CHL, aminoglycosides, TMP, FOS, polymyxins	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Elizabethkingia meningoseptica			aminopenicillins, AMC, TIC, CZO, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM, polymyxins	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Ochrobactrum anthropi			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, CAZ, FEP, ATM, ETP	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Pseudomonas aeruginosa			aminopenicillins, AMC, CZO, CTX, CRO, ETP, CHL, KAN, NEO, TMP, SXT, tetracyclines, TGC	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus_species	is	Stenotrophomonas maltophilia			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, ATM, ETP, IPM, MEM, aminoglycosides, TMP, FOS, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules
genus	one_of	Haemophilus, Moraxella, Neisseria, Campylobacter			glycopeptides, LIN, DAP, LNZ	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Haemophilus influenzae			FUS, streptogramins	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Moraxella catarrhalis			TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus	is	Neisseria			TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Campylobacter fetus			FUS, streptogramins, TMP, NAL	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Campylobacter jejuni			FUS, streptogramins, TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
genus_species	is	Campylobacter coli			FUS, streptogramins, TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules
gramstain	is	Gram-positive			ATM, polymyxins, NAL	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus saprophyticus			FUS, CAZ, FOS, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus cohnii			CAZ, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus xylosus			CAZ, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus capitis			CAZ, FOS	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus aureus			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus epidermidis			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus coagulase-negative			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus hominis			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus haemolyticus			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus intermedius			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Staphylococcus pseudintermedius			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	is	Streptococcus			FUS, CAZ, aminoglycosides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus faecalis			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus gallinarum			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus casseliflavus			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Enterococcus faecium			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	is	Corynebacterium			FOS	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Listeria monocytogenes			cephalosporins	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	one_of	Leuconostoc, Pediococcus			glycopeptides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus	is	Lactobacillus			glycopeptides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Clostridium ramosum			VAN	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	is	Clostridium innocuum			VAN	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules
genus_species	like	^Streptococcus (pyogenes|agalactiae|dysgalactiae|group A|group B|group C|group G)	PEN	S	aminopenicillins, cephalosporins_except_CAZ, carbapenems	S	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules
genus	is	Enterococcus	AMP	R	ureidopenicillins, carbapenems	R	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules
genus	is	Enterococcus	AMX	R	ureidopenicillins, carbapenems	R	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules
family	is	Enterobacteriaceae	TIC, PIP	R, S	PIP	R	Table 09: Interpretive rules for B-lactam agents and Gram-negative rods	Expert Rules
genus	like	.*	ERY	S	AZM, CLR	S	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules
genus	like	.*	ERY	I	AZM, CLR	I	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules
genus	like	.*	ERY	R	AZM, CLR	R	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules
genus	is	Staphylococcus	TOB	R	KAN, AMK	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
genus	is	Staphylococcus	GEN	R	aminoglycosides	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
order	is	Enterobacterales	GEN, TOB	I, S	GEN	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
order	is	Enterobacterales	GEN, TOB	R, I	TOB	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules
genus	is	Staphylococcus	MFX	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules
genus_species	is	Streptococcus pneumoniae	MFX	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules
order	is	Enterobacterales	CIP	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules
genus_species	is	Neisseria gonorrhoeae	CIP	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules