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get episode unit tests

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2023-02-24 19:54:56 +01:00
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commit 1d3d7d40bc
5 changed files with 89 additions and 74 deletions

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@ -29,50 +29,52 @@
#' Determine (Clinical or Epidemic) Episodes
#'
#' These functions determine which items in a vector can be considered (the start of) a new episode, based on the argument `episode_days`. This can be used to determine clinical episodes for any epidemiological analysis. The [get_episode()] function returns the index number of the episode per group, while the [is_new_episode()] function returns `TRUE` for every new [get_episode()] index. Both absolute and relative episode determination are supported.
#' These functions determine which items in a vector can be considered (the start of) a new episode. This can be used to determine clinical episodes for any epidemiological analysis. The [get_episode()] function returns the index number of the episode per group, while the [is_new_episode()] function returns `TRUE` for every new [get_episode()] index. Both absolute and relative episode determination are supported.
#' @param x vector of dates (class `Date` or `POSIXt`), will be sorted internally to determine episodes
#' @param episode_days episode length in days, can also be less than a day or `Inf`, see *Details*
#' @param case_free_days length in days after which new episode will start, can also be less than a day or `Inf`, see *Details*
#' @param episode_days episode length in days to specify the time period after which a new episode begins, can also be less than a day or `Inf`, see *Details*
#' @param case_free_days (inter-epidemic) interval length in days after which a new episode will start, can also be less than a day or `Inf`, see *Details*
#' @param ... ignored, only in place to allow future extensions
#' @details Episodes can be determined in two ways: absolute and relative.
#'
#'
#' 1. Absolute
#'
#'
#' This method uses `episode_days` to define an episode length in days, after which a new episode will start. A common use case in AMR data analysis is microbial epidemiology: episodes of *S. aureus* bacteraemia in ICU patients for example. The episode length could then be 30 days, so that new *S. aureus* isolates after an ICU episode of 30 days will be considered a different (or new) episode.
#'
#'
#' Thus, this method counts **since the start of the previous episode**.
#'
#'
#' 2. Relative
#'
#' This method uses `case_free_days` to quantify the duration of (inter-epidemic) intervals, after which a new episode will start. A common use case is infectious disease epidemiology: episodes of norovirus outbreaks in a hospital for example. The case-free period could then be 14 days, so that new norovirus cases after that time will be considered a different (or new) episode.
#'
#'
#' This method uses `case_free_days` to quantify the duration of case-free days (the inter-epidemic interval), after which a new episode will start. A common use case is infectious disease epidemiology: episodes of norovirus outbreaks in a hospital for example. The case-free period could then be 14 days, so that new norovirus cases after that time will be considered a different (or new) episode.
#'
#' Thus, this methods counts **since the last case in the previous episode**.
#'
#'
#' In a table:
#'
#'
#' | Date | Using `episode_days = 7` | Using `case_free_days = 7` |
#' |:----------:|:------------------------:|:--------------------------:|
#' | 2023-01-01 | 1 | 1 |
#' | 2023-01-02 | 1 | 1 |
#' | 2023-01-05 | 1 | 1 |
#' | 2023-01-08 | 2\code{*} | 1 |
#' | 2023-02-21 | 3 | 2\code{**} |
#' | 2023-01-08 | 2** | 1 |
#' | 2023-02-21 | 3 | 2*** |
#' | 2023-02-22 | 3 | 2 |
#' | 2023-02-23 | 3 | 2 |
#' | 2023-02-24 | 3 | 2 |
#' | 2023-03-01 | 4 | 2 |
#'
#' \code{*} This marks the start of a new episode, because 8 January 2023 is more than 7 days since the start of the previous episode (1 January 2023). \cr
#' \code{**} This marks the start of a new episode, because 21 January 2023 is more than 7 days since the last case in the previous episode (8 January 2023).
#'
#'
#' ** This marks the start of a new episode, because 8 January 2023 is more than 7 days since the start of the previous episode (1 January 2023). \cr
#' *** This marks the start of a new episode, because 21 January 2023 is more than 7 days since the last case in the previous episode (8 January 2023).
#'
#' Either `episode_days` or `case_free_days` must be provided in the function.
#'
#' ### Difference between `get_episode()` and `is_new_episode()`
#'
#' The [get_episode()] function returns the index number of the episode, so all cases/patients/isolates in the first episode will have the number 1, all cases/patients/isolates in the second episode will have the number 2, etc.
#'
#'
#' The [get_episode()] function returns the index number of the episode, so all cases/patients/isolates in the first episode will have the number 1, all cases/patients/isolates in the second episode will have the number 2, etc.
#'
#' The [is_new_episode()] function returns `TRUE` for every new [get_episode()] index, and is thus equal to `!duplicated(get_episode(...))`.
#'
#'
#' To specify, when setting `episode_days = 365` (using method 1 as explained above), this is how the two functions differ:
#'
#'
#' | patient | date | `get_episode()` | `is_new_episode()` |
#' |:---------:|:----------:|:---------------:|:------------------:|
#' | A | 2019-01-01 | 1 | TRUE |
@ -83,7 +85,7 @@
#' | C | 2020-01-01 | 1 | TRUE |
#'
#' ### Other
#'
#'
#' The [first_isolate()] function is a wrapper around the [is_new_episode()] function, but is more efficient for data sets containing microorganism codes or names and allows for different isolate selection methods.
#'
#' The `dplyr` package is not required for these functions to work, but these episode functions do support [variable grouping][dplyr::group_by()] and work conveniently inside `dplyr` verbs such as [`filter()`][dplyr::filter()], [`mutate()`][dplyr::mutate()] and [`summarise()`][dplyr::summarise()].
@ -110,8 +112,8 @@
#' x$absolute <- get_episode(x$dates, episode_days = 7)
#' x$relative <- get_episode(x$dates, case_free_days = 7)
#' x
#'
#'
#'
#'
#' # `example_isolates` is a data set available in the AMR package.
#' # See ?example_isolates
#' df <- example_isolates[sample(seq_len(2000), size = 100), ]
@ -213,51 +215,54 @@ is_new_episode <- function(x, episode_days = NULL, case_free_days = NULL, ...) {
exec_episode <- function(x, episode_days, case_free_days, ...) {
stop_if((is.null(episode_days) && is.null(case_free_days)) || (!is.null(episode_days) && !is.null(case_free_days)),
"either `episode_days` or `case_free_days` must be set.", call = -2)
"either `episode_days` or `case_free_days` must be set.",
call = -2
)
x <- as.double(as.POSIXct(x)) # as.POSIXct() required for Date classes
# running as.double() on a POSIXct object will return its number of seconds since 1970-01-01
x <- as.double(as.POSIXct(x)) # as.POSIXct() required for Date classes
# since x is now in seconds, get seconds from episode_days as well
episode_seconds <- episode_days * 60 * 60 * 24
case_free_seconds <- case_free_days * 60 * 60 * 24
# since x is now in seconds, get seconds from episode_days as well
episode_seconds <- episode_days * 60 * 60 * 24
case_free_seconds <- case_free_days * 60 * 60 * 24
if (length(x) == 1) { # this will also match 1 NA, which is fine
return(1)
} else if (length(x) == 2 && all(!is.na(x))) {
if ((length(episode_seconds) > 0 && (max(x) - min(x)) >= episode_seconds) ||
(length(case_free_seconds) > 0 && (max(x) - min(x)) >= case_free_seconds)) {
if (x[1] <= x[2]) {
return(c(1, 2))
} else {
return(c(2, 1))
}
if (length(x) == 1) { # this will also match 1 NA, which is fine
return(1)
} else if (length(x) == 2 && all(!is.na(x))) {
if ((length(episode_seconds) > 0 && (max(x) - min(x)) >= episode_seconds) ||
(length(case_free_seconds) > 0 && (max(x) - min(x)) >= case_free_seconds)) {
if (x[1] <= x[2]) {
return(c(1, 2))
} else {
return(c(1, 1))
return(c(2, 1))
}
} else {
return(c(1, 1))
}
}
run_episodes <- function(x, episode_seconds, case_free) {
NAs <- which(is.na(x))
x[NAs] <- 0
indices <- integer(length = length(x))
start <- x[1]
ind <- 1
indices[ind] <- 1
for (i in 2:length(x)) {
if ((length(episode_seconds) > 0 && (x[i] - start) >= episode_seconds) ||
(length(case_free_seconds) > 0 && (x[i] - x[i - 1]) >= case_free_seconds)) {
ind <- ind + 1
start <- x[i]
}
indices[i] <- ind
run_episodes <- function(x, episode_seconds, case_free) {
NAs <- which(is.na(x))
x[NAs] <- 0
indices <- integer(length = length(x))
start <- x[1]
ind <- 1
indices[ind] <- 1
for (i in 2:length(x)) {
if ((length(episode_seconds) > 0 && (x[i] - start) >= episode_seconds) ||
(length(case_free_seconds) > 0 && (x[i] - x[i - 1]) >= case_free_seconds)) {
ind <- ind + 1
start <- x[i]
}
indices[NAs] <- NA
indices
indices[i] <- ind
}
ord <- order(x)
out <- run_episodes(x[ord], episode_seconds, case_free_seconds)[order(ord)]
out[is.na(x) & ord != 1] <- NA # every NA expect for the first must remain NA
out
indices[NAs] <- NA
indices
}
ord <- order(x)
out <- run_episodes(x[ord], episode_seconds, case_free_seconds)[order(ord)]
out[is.na(x) & ord != 1] <- NA # every NA expect for the first must remain NA
out
}