mirror of
https://github.com/msberends/AMR.git
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- For functions first_isolate
, EUCAST_rules
the antibiotic column names are case-insensitive
- Functions `first_isolate`, `EUCAST_rules` and `rsi_predict` supports tidyverse-like evaluation of parameters (no need to quote columns them anymore) - Functions `clipboard_import` and `clipboard_export` as helper functions to quickly copy and paste from/to software like Excel and SPSS - Renamed dataset `bactlist` to `microorganisms`
This commit is contained in:
parent
e1e19af625
commit
53464ff1c8
@ -1,6 +1,6 @@
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Package: AMR
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Package: AMR
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Version: 0.1.2
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Version: 0.1.2
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Date: 2018-03-19
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Date: 2018-03-23
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Title: Antimicrobial Resistance Analysis
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Title: Antimicrobial Resistance Analysis
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Authors@R: c(
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Authors@R: c(
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person(
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person(
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@ -25,8 +25,8 @@ Description: Functions to simplify the analysis of Antimicrobial Resistance (AMR
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on antibiograms according to Leclercq (2013)
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on antibiograms according to Leclercq (2013)
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<doi:10.1111/j.1469-0691.2011.03703.x>.
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<doi:10.1111/j.1469-0691.2011.03703.x>.
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Depends: R (>= 3.0)
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Depends: R (>= 3.0)
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Imports: dplyr (>= 0.7.0), reshape2 (>= 1.4.0), xml2, rvest
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Imports: dplyr (>= 0.7.0), knitr, reshape2 (>= 1.4.0), xml2, rvest
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URL: https://github.com/msberends/AMR
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URL: https://cran.r-project.org/package=AMR
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BugReports: https://github.com/msberends/AMR/issues
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BugReports: https://github.com/msberends/AMR/issues
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License: GPL-2 | file LICENSE
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License: GPL-2 | file LICENSE
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Encoding: UTF-8
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Encoding: UTF-8
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19
NAMESPACE
19
NAMESPACE
@ -13,25 +13,27 @@ S3method(summary,mic)
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S3method(summary,rsi)
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S3method(summary,rsi)
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export(EUCAST_rules)
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export(EUCAST_rules)
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export(abname)
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export(abname)
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export(anti_join_bactlist)
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export(anti_join_microorganisms)
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export(as.mic)
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export(as.mic)
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export(as.rsi)
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export(as.rsi)
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export(atc_property)
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export(atc_property)
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export(clipboard_export)
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export(clipboard_import)
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export(first_isolate)
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export(first_isolate)
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export(full_join_bactlist)
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export(full_join_microorganisms)
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export(guess_bactid)
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export(guess_bactid)
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export(inner_join_bactlist)
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export(inner_join_microorganisms)
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export(interpretive_reading)
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export(interpretive_reading)
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export(is.mic)
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export(is.mic)
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export(is.rsi)
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export(is.rsi)
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export(key_antibiotics)
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export(key_antibiotics)
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export(left_join_bactlist)
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export(left_join_microorganisms)
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export(mo_property)
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export(mo_property)
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export(right_join_bactlist)
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export(right_join_microorganisms)
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export(rsi)
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export(rsi)
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export(rsi_df)
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export(rsi_df)
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export(rsi_predict)
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export(rsi_predict)
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export(semi_join_bactlist)
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export(semi_join_microorganisms)
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exportMethods(as.double.mic)
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exportMethods(as.double.mic)
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exportMethods(as.integer.mic)
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exportMethods(as.integer.mic)
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exportMethods(as.numeric.mic)
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exportMethods(as.numeric.mic)
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@ -48,6 +50,7 @@ importFrom(dplyr,all_vars)
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importFrom(dplyr,any_vars)
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importFrom(dplyr,any_vars)
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importFrom(dplyr,arrange)
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importFrom(dplyr,arrange)
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importFrom(dplyr,arrange_at)
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importFrom(dplyr,arrange_at)
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importFrom(dplyr,as_tibble)
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importFrom(dplyr,between)
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importFrom(dplyr,between)
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importFrom(dplyr,filter)
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importFrom(dplyr,filter)
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importFrom(dplyr,filter_at)
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importFrom(dplyr,filter_at)
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@ -73,5 +76,9 @@ importFrom(graphics,text)
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importFrom(reshape2,dcast)
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importFrom(reshape2,dcast)
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importFrom(rvest,html_nodes)
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importFrom(rvest,html_nodes)
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importFrom(rvest,html_table)
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importFrom(rvest,html_table)
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importFrom(utils,object.size)
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importFrom(utils,packageDescription)
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importFrom(utils,packageDescription)
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importFrom(utils,read.delim)
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importFrom(utils,write.table)
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importFrom(utils,writeClipboard)
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importFrom(xml2,read_html)
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importFrom(xml2,read_html)
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17
NEWS
17
NEWS
@ -1,11 +1,14 @@
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## 0.1.2
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## 0.1.2
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- Added new function `guess_bactid` to determine the ID of a microorganism based on genus/species
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- NEW: Function `guess_bactid` to determine the ID of a microorganism based on genus/species
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- Renamed `ablist` to `antibiotics`
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- NEW: Functions `clipboard_import` and `clipboard_export` as helper functions to quickly copy and paste from/to software like Excel and SPSS
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- Added support for character vector in join functions
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- NEW: New algorithm to determine weighted isolates, can now be `"points"` or `"keyantibiotics"`, see `?first_isolate`
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- Altered `%like%` to make it case insensitive
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- EDIT: Renamed dataset `ablist` to `antibiotics`
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- Added new algorithm to determine weighted isolates, can now be `points` or `keyantibiotics, see `?first_isolate`
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- EDIT: Renamed dataset `bactlist` to `microorganisms`
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- Function `first_isolate` supports tidyverse-like evaluation of parameters (no need to quote them anymore)
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- EDIT: Added support for character vector in join functions
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- Functions `as.rsi` and `as.mic` now add the package name and version as attribute
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- EDIT: Altered `%like%` to make it case insensitive
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- EDIT: Functions `first_isolate`, `EUCAST_rules` and `rsi_predict` supports tidyverse-like evaluation of parameters (no need to quote columns them anymore)
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- EDIT: For functions `first_isolate`, `EUCAST_rules` the antibiotic column names are case-insensitive
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- EDIT: Functions `as.rsi` and `as.mic` now add the package name and version as attribute
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## 0.1.1
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## 0.1.1
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- `EUCAST_rules` applies for amoxicillin even if ampicillin is missing
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- `EUCAST_rules` applies for amoxicillin even if ampicillin is missing
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420
R/EUCAST.R
420
R/EUCAST.R
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#'
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#'
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#' Apply expert rules (like intrinsic resistance), as defined by the European Committee on Antimicrobial Susceptibility Testing (EUCAST, \url{http://eucast.org}), see \emph{Source}.
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#' Apply expert rules (like intrinsic resistance), as defined by the European Committee on Antimicrobial Susceptibility Testing (EUCAST, \url{http://eucast.org}), see \emph{Source}.
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#' @param tbl table with antibiotic columns, like e.g. \code{amox} and \code{amcl}
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#' @param tbl table with antibiotic columns, like e.g. \code{amox} and \code{amcl}
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#' @param col_bactcode column name of the bacteria ID in \code{tbl} - values of this column should be present in \code{bactlist$bactid}, see \code{\link{bactlist}}
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#' @param col_bactid column name of the bacteria ID in \code{tbl} - values of this column should be present in \code{microorganisms$bactid}, see \code{\link{microorganisms}}
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#' @param info print progress
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#' @param info print progress
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#' @param amcl,amik,amox,ampi,azit,aztr,cefa,cfra,cfep,cfot,cfox,cfta,cftr,cfur,chlo,cipr,clar,clin,clox,coli,czol,dapt,doxy,erta,eryt,fosf,fusi,gent,imip,kana,levo,linc,line,mero,mino,moxi,nali,neom,neti,nitr,novo,norf,oflo,peni,pita,poly,qida,rifa,roxi,siso,teic,tetr,tica,tige,tobr,trim,trsu,vanc column names of antibiotics. Use \code{NA} to skip a column, like \code{tica = NA}. Non-existing column will be skipped.
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#' @param amcl,amik,amox,ampi,azit,aztr,cefa,cfra,cfep,cfot,cfox,cfta,cftr,cfur,chlo,cipr,clar,clin,clox,coli,czol,dapt,doxy,erta,eryt,fosf,fusi,gent,imip,kana,levo,linc,line,mero,mino,moxi,nali,neom,neti,nitr,novo,norf,oflo,peni,pita,poly,qida,rifa,roxi,siso,teic,tetr,tica,tige,tobr,trim,trsu,vanc column names of antibiotics. Use \code{NA} to skip a column, like \code{tica = NA}. Non-existing column will be skipped.
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#' @param ... parameters that are passed on to \code{EUCAST_rules}
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#' @param ... parameters that are passed on to \code{EUCAST_rules}
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@ -33,8 +33,8 @@
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#' Leclercq et al. \strong{EUCAST expert rules in antimicrobial susceptibility testing.} \emph{Clin Microbiol Infect.} 2013;19(2):141-60. \cr
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#' Leclercq et al. \strong{EUCAST expert rules in antimicrobial susceptibility testing.} \emph{Clin Microbiol Infect.} 2013;19(2):141-60. \cr
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#' \url{https://doi.org/10.1111/j.1469-0691.2011.03703.x} \cr
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#' \url{https://doi.org/10.1111/j.1469-0691.2011.03703.x} \cr
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#' \cr
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#' \cr
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#' EUCAST Expert Rules Version 3.1: \cr
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#' EUCAST Expert Rules Version 3.1 (Intrinsic Resistance and Exceptional Phenotypes Tables): \cr
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#' \url{http://www.eucast.org/expert_rules_and_intrinsic_resistance}
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#' \url{http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Expert_Rules/Expert_rules_intrinsic_exceptional_V3.1.pdf}
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#' @examples
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#' @examples
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#' a <- data.frame(bactid = c("STAAUR", # Staphylococcus aureus
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#' a <- data.frame(bactid = c("STAAUR", # Staphylococcus aureus
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#' "ENCFAE", # Enterococcus faecalis
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#' "ENCFAE", # Enterococcus faecalis
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#' b <- EUCAST_rules(a)
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#' b <- EUCAST_rules(a)
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#' b
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#' b
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EUCAST_rules <- function(tbl,
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EUCAST_rules <- function(tbl,
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col_bactcode = 'bactid',
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col_bactid = 'bactid',
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info = TRUE,
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info = TRUE,
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amcl = 'amcl',
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amcl = 'amcl',
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amik = 'amik',
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amik = 'amik',
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@ -112,95 +112,168 @@ EUCAST_rules <- function(tbl,
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trim = 'trim',
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trim = 'trim',
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trsu = 'trsu',
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trsu = 'trsu',
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vanc = 'vanc') {
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vanc = 'vanc') {
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EUCAST_VERSION <- "3.1"
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if (!col_bactcode %in% colnames(tbl)) {
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# support using columns as objects; the tidyverse way
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stop('Column ', col_bactcode, ' not found.')
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amcl <- quasiquotate(deparse(substitute(amcl)), amcl)
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amik <- quasiquotate(deparse(substitute(amik)), amik)
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amox <- quasiquotate(deparse(substitute(amox)), amox)
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ampi <- quasiquotate(deparse(substitute(ampi)), ampi)
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azit <- quasiquotate(deparse(substitute(azit)), azit)
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aztr <- quasiquotate(deparse(substitute(aztr)), aztr)
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cefa <- quasiquotate(deparse(substitute(cefa)), cefa)
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cfra <- quasiquotate(deparse(substitute(cfra)), cfra)
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cfep <- quasiquotate(deparse(substitute(cfep)), cfep)
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cfot <- quasiquotate(deparse(substitute(cfot)), cfot)
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cfox <- quasiquotate(deparse(substitute(cfox)), cfox)
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cfta <- quasiquotate(deparse(substitute(cfta)), cfta)
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cftr <- quasiquotate(deparse(substitute(cftr)), cftr)
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cfur <- quasiquotate(deparse(substitute(cfur)), cfur)
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chlo <- quasiquotate(deparse(substitute(chlo)), chlo)
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cipr <- quasiquotate(deparse(substitute(cipr)), cipr)
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clar <- quasiquotate(deparse(substitute(clar)), clar)
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clin <- quasiquotate(deparse(substitute(clin)), clin)
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clox <- quasiquotate(deparse(substitute(clox)), clox)
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coli <- quasiquotate(deparse(substitute(coli)), coli)
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czol <- quasiquotate(deparse(substitute(czol)), czol)
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dapt <- quasiquotate(deparse(substitute(dapt)), dapt)
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doxy <- quasiquotate(deparse(substitute(doxy)), doxy)
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erta <- quasiquotate(deparse(substitute(erta)), erta)
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eryt <- quasiquotate(deparse(substitute(eryt)), eryt)
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fosf <- quasiquotate(deparse(substitute(fosf)), fosf)
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fusi <- quasiquotate(deparse(substitute(fusi)), fusi)
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gent <- quasiquotate(deparse(substitute(gent)), gent)
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imip <- quasiquotate(deparse(substitute(imip)), imip)
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kana <- quasiquotate(deparse(substitute(kana)), kana)
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levo <- quasiquotate(deparse(substitute(levo)), levo)
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linc <- quasiquotate(deparse(substitute(linc)), linc)
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line <- quasiquotate(deparse(substitute(line)), line)
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mero <- quasiquotate(deparse(substitute(mero)), mero)
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mino <- quasiquotate(deparse(substitute(mino)), mino)
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moxi <- quasiquotate(deparse(substitute(moxi)), moxi)
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nali <- quasiquotate(deparse(substitute(nali)), nali)
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neom <- quasiquotate(deparse(substitute(neom)), neom)
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neti <- quasiquotate(deparse(substitute(neti)), neti)
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nitr <- quasiquotate(deparse(substitute(nitr)), nitr)
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novo <- quasiquotate(deparse(substitute(novo)), novo)
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norf <- quasiquotate(deparse(substitute(norf)), norf)
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oflo <- quasiquotate(deparse(substitute(oflo)), oflo)
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peni <- quasiquotate(deparse(substitute(peni)), peni)
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pita <- quasiquotate(deparse(substitute(pita)), pita)
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poly <- quasiquotate(deparse(substitute(poly)), poly)
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qida <- quasiquotate(deparse(substitute(qida)), qida)
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rifa <- quasiquotate(deparse(substitute(rifa)), rifa)
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roxi <- quasiquotate(deparse(substitute(roxi)), roxi)
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siso <- quasiquotate(deparse(substitute(siso)), siso)
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teic <- quasiquotate(deparse(substitute(teic)), teic)
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tetr <- quasiquotate(deparse(substitute(tetr)), tetr)
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tica <- quasiquotate(deparse(substitute(tica)), tica)
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tige <- quasiquotate(deparse(substitute(tige)), tige)
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tobr <- quasiquotate(deparse(substitute(tobr)), tobr)
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trim <- quasiquotate(deparse(substitute(trim)), trim)
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trsu <- quasiquotate(deparse(substitute(trsu)), trsu)
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vanc <- quasiquotate(deparse(substitute(vanc)), vanc)
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if (!col_bactid %in% colnames(tbl)) {
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stop('Column ', col_bactid, ' not found.')
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}
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}
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# kolommen controleren
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# check columns
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col.list <- c(amcl, amik, amox, ampi, azit, aztr, cefa, cfra, cfep,
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col.list <- c(amcl, amik, amox, ampi, azit, aztr, cefa, cfra, cfep, cfot,
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cfot, cfox, cfta, cftr, cfur, cipr, clar, clin, clox, coli, czol,
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cfox, cfta, cftr, cfur, chlo, cipr, clar, clin, clox, coli,
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dapt, doxy, erta, eryt, fusi, gent, imip, kana, levo, linc, line,
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czol, dapt, doxy, erta, eryt, fosf, fusi, gent, imip, kana,
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mero, mino, moxi, nali, neom, neti, nitr, novo, norf, oflo, peni,
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levo, linc, line, mero, mino, moxi, nali, neom, neti, nitr,
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pita, poly, qida, rifa, roxi, siso, teic, tetr, tica, tige, tobr,
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novo, norf, oflo, peni, pita, poly, qida, rifa, roxi, siso,
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trim, trsu, vanc)
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teic, tetr, tica, tige, tobr, trim, trsu, vanc)
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col.list <- col.list[!is.na(col.list)]
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col.list <- col.list[!is.na(col.list)]
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col.list.bak <- col.list
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# are they available as upper case then?
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for (i in 1:length(col.list)) {
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if (toupper(col.list[i]) %in% colnames(tbl)) {
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col.list[i] <- toupper(col.list[i])
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} else if (tolower(col.list[i]) %in% colnames(tbl)) {
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col.list[i] <- tolower(col.list[i])
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} else if (!col.list[i] %in% colnames(tbl)) {
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col.list[i] <- NA
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}
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}
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if (!all(col.list %in% colnames(tbl))) {
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if (!all(col.list %in% colnames(tbl))) {
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if (info == TRUE) {
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if (info == TRUE) {
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cat('\n')
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cat('\n')
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}
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}
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if (info == TRUE) {
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if (info == TRUE) {
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warning('These columns do not exist and will be ignored:\n',
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warning('These columns do not exist and will be ignored: ',
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col.list[!(col.list %in% colnames(tbl))] %>% toString(),
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col.list.bak[!(col.list %in% colnames(tbl))] %>% toString(),
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immediate. = TRUE,
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immediate. = TRUE,
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call. = FALSE)
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call. = FALSE)
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}
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}
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if (!amcl %in% colnames(tbl)) { amcl <- NA }
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if (!amik %in% colnames(tbl)) { amik <- NA }
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if (!amox %in% colnames(tbl)) { amox <- NA }
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if (!ampi %in% colnames(tbl)) { ampi <- NA }
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if (!azit %in% colnames(tbl)) { azit <- NA }
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if (!aztr %in% colnames(tbl)) { aztr <- NA }
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if (!cefa %in% colnames(tbl)) { cefa <- NA }
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if (!cfra %in% colnames(tbl)) { cfra <- NA }
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if (!cfep %in% colnames(tbl)) { cfep <- NA }
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if (!cfot %in% colnames(tbl)) { cfot <- NA }
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if (!cfox %in% colnames(tbl)) { cfox <- NA }
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if (!cfta %in% colnames(tbl)) { cfta <- NA }
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if (!cftr %in% colnames(tbl)) { cftr <- NA }
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if (!cfur %in% colnames(tbl)) { cfur <- NA }
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||||||
if (!chlo %in% colnames(tbl)) { chlo <- NA }
|
|
||||||
if (!cipr %in% colnames(tbl)) { cipr <- NA }
|
|
||||||
if (!clar %in% colnames(tbl)) { clar <- NA }
|
|
||||||
if (!clin %in% colnames(tbl)) { clin <- NA }
|
|
||||||
if (!clox %in% colnames(tbl)) { clox <- NA }
|
|
||||||
if (!coli %in% colnames(tbl)) { coli <- NA }
|
|
||||||
if (!czol %in% colnames(tbl)) { czol <- NA }
|
|
||||||
if (!dapt %in% colnames(tbl)) { dapt <- NA }
|
|
||||||
if (!doxy %in% colnames(tbl)) { doxy <- NA }
|
|
||||||
if (!erta %in% colnames(tbl)) { erta <- NA }
|
|
||||||
if (!eryt %in% colnames(tbl)) { eryt <- NA }
|
|
||||||
if (!fosf %in% colnames(tbl)) { fosf <- NA }
|
|
||||||
if (!fusi %in% colnames(tbl)) { fusi <- NA }
|
|
||||||
if (!gent %in% colnames(tbl)) { gent <- NA }
|
|
||||||
if (!imip %in% colnames(tbl)) { imip <- NA }
|
|
||||||
if (!kana %in% colnames(tbl)) { kana <- NA }
|
|
||||||
if (!levo %in% colnames(tbl)) { levo <- NA }
|
|
||||||
if (!linc %in% colnames(tbl)) { linc <- NA }
|
|
||||||
if (!line %in% colnames(tbl)) { line <- NA }
|
|
||||||
if (!mero %in% colnames(tbl)) { mero <- NA }
|
|
||||||
if (!mino %in% colnames(tbl)) { mino <- NA }
|
|
||||||
if (!moxi %in% colnames(tbl)) { moxi <- NA }
|
|
||||||
if (!nali %in% colnames(tbl)) { nali <- NA }
|
|
||||||
if (!neom %in% colnames(tbl)) { neom <- NA }
|
|
||||||
if (!neti %in% colnames(tbl)) { neti <- NA }
|
|
||||||
if (!nitr %in% colnames(tbl)) { nitr <- NA }
|
|
||||||
if (!novo %in% colnames(tbl)) { novo <- NA }
|
|
||||||
if (!norf %in% colnames(tbl)) { norf <- NA }
|
|
||||||
if (!oflo %in% colnames(tbl)) { oflo <- NA }
|
|
||||||
if (!peni %in% colnames(tbl)) { peni <- NA }
|
|
||||||
if (!pita %in% colnames(tbl)) { pita <- NA }
|
|
||||||
if (!poly %in% colnames(tbl)) { poly <- NA }
|
|
||||||
if (!qida %in% colnames(tbl)) { qida <- NA }
|
|
||||||
if (!rifa %in% colnames(tbl)) { rifa <- NA }
|
|
||||||
if (!roxi %in% colnames(tbl)) { roxi <- NA }
|
|
||||||
if (!siso %in% colnames(tbl)) { siso <- NA }
|
|
||||||
if (!teic %in% colnames(tbl)) { teic <- NA }
|
|
||||||
if (!tetr %in% colnames(tbl)) { tetr <- NA }
|
|
||||||
if (!tica %in% colnames(tbl)) { tica <- NA }
|
|
||||||
if (!tige %in% colnames(tbl)) { tige <- NA }
|
|
||||||
if (!tobr %in% colnames(tbl)) { tobr <- NA }
|
|
||||||
if (!trim %in% colnames(tbl)) { trim <- NA }
|
|
||||||
if (!trsu %in% colnames(tbl)) { trsu <- NA }
|
|
||||||
if (!vanc %in% colnames(tbl)) { vanc <- NA }
|
|
||||||
}
|
}
|
||||||
|
|
||||||
|
amcl <- col.list[1]
|
||||||
|
amik <- col.list[2]
|
||||||
|
amox <- col.list[3]
|
||||||
|
ampi <- col.list[4]
|
||||||
|
azit <- col.list[5]
|
||||||
|
aztr <- col.list[6]
|
||||||
|
cefa <- col.list[7]
|
||||||
|
cfra <- col.list[8]
|
||||||
|
cfep <- col.list[9]
|
||||||
|
cfot <- col.list[10]
|
||||||
|
cfox <- col.list[11]
|
||||||
|
cfta <- col.list[12]
|
||||||
|
cftr <- col.list[13]
|
||||||
|
cfur <- col.list[14]
|
||||||
|
chlo <- col.list[15]
|
||||||
|
cipr <- col.list[16]
|
||||||
|
clar <- col.list[17]
|
||||||
|
clin <- col.list[18]
|
||||||
|
clox <- col.list[19]
|
||||||
|
coli <- col.list[20]
|
||||||
|
czol <- col.list[21]
|
||||||
|
dapt <- col.list[22]
|
||||||
|
doxy <- col.list[23]
|
||||||
|
erta <- col.list[24]
|
||||||
|
eryt <- col.list[25]
|
||||||
|
fosf <- col.list[26]
|
||||||
|
fusi <- col.list[27]
|
||||||
|
gent <- col.list[28]
|
||||||
|
imip <- col.list[29]
|
||||||
|
kana <- col.list[30]
|
||||||
|
levo <- col.list[31]
|
||||||
|
linc <- col.list[32]
|
||||||
|
line <- col.list[33]
|
||||||
|
mero <- col.list[34]
|
||||||
|
mino <- col.list[35]
|
||||||
|
moxi <- col.list[36]
|
||||||
|
nali <- col.list[37]
|
||||||
|
neom <- col.list[38]
|
||||||
|
neti <- col.list[39]
|
||||||
|
nitr <- col.list[40]
|
||||||
|
novo <- col.list[41]
|
||||||
|
norf <- col.list[42]
|
||||||
|
oflo <- col.list[43]
|
||||||
|
peni <- col.list[44]
|
||||||
|
pita <- col.list[45]
|
||||||
|
poly <- col.list[46]
|
||||||
|
qida <- col.list[47]
|
||||||
|
rifa <- col.list[48]
|
||||||
|
roxi <- col.list[49]
|
||||||
|
siso <- col.list[50]
|
||||||
|
teic <- col.list[51]
|
||||||
|
tetr <- col.list[52]
|
||||||
|
tica <- col.list[53]
|
||||||
|
tige <- col.list[54]
|
||||||
|
tobr <- col.list[55]
|
||||||
|
trim <- col.list[56]
|
||||||
|
trsu <- col.list[57]
|
||||||
|
vanc <- col.list[58]
|
||||||
|
|
||||||
total <- 0
|
total <- 0
|
||||||
total_rows <- integer(0)
|
total_rows <- integer(0)
|
||||||
|
|
||||||
# functie voor uitvoeren
|
# helper function for editing the table
|
||||||
edit_rsi <- function(to, rows, cols) {
|
edit_rsi <- function(to, rows, cols) {
|
||||||
#voortgang$tick()$print()
|
|
||||||
cols <- cols[!is.na(cols)]
|
cols <- cols[!is.na(cols)]
|
||||||
if (length(rows) > 0 & length(cols) > 0) {
|
if (length(rows) > 0 & length(cols) > 0) {
|
||||||
tbl[rows, cols] <<- to
|
tbl[rows, cols] <<- to
|
||||||
@ -209,97 +282,99 @@ EUCAST_rules <- function(tbl,
|
|||||||
}
|
}
|
||||||
}
|
}
|
||||||
|
|
||||||
# bactlist aan vastknopen (bestaande kolommen krijgen extra suffix)
|
# join to microorganisms table
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- col_bactcode
|
names(joinby) <- col_bactid
|
||||||
tbl <- tbl %>% left_join(y = AMR::bactlist, by = joinby, suffix = c("_tempbactlist", ""))
|
tbl <- tbl %>% left_join(y = AMR::microorganisms, by = joinby, suffix = c("_tempmicroorganisms", ""))
|
||||||
|
|
||||||
# antibioticagroepen
|
# antibiotic classes
|
||||||
aminoglycosiden <- c(tobr, gent, kana, neom, neti, siso)
|
aminoglycosides <- c(tobr, gent, kana, neom, neti, siso)
|
||||||
tetracyclines <- c(doxy, mino, tetr) # sinds EUCAST v3.1 is tige(cycline) apart
|
tetracyclines <- c(doxy, mino, tetr) # since EUCAST v3.1 tige(cycline) is set apart
|
||||||
polymyxines <- c(poly, coli)
|
polymyxins <- c(poly, coli)
|
||||||
macroliden <- c(eryt, azit, roxi, clar) # sinds EUCAST v3.1 is clinda apart
|
macrolides <- c(eryt, azit, roxi, clar) # since EUCAST v3.1 clinda is set apart
|
||||||
glycopeptiden <- c(vanc, teic)
|
glycopeptides <- c(vanc, teic)
|
||||||
streptogramines <- qida # eigenlijk pristinamycine en quinupristine/dalfopristine
|
streptogramins <- qida # should officially also be pristinamycin and quinupristin/dalfopristin
|
||||||
cefalosporines <- c(cfep, cfot, cfox, cfra, cfta, cftr, cfur, czol)
|
cephalosporins <- c(cfep, cfot, cfox, cfra, cfta, cftr, cfur, czol)
|
||||||
carbapenems <- c(erta, imip, mero)
|
carbapenems <- c(erta, imip, mero)
|
||||||
aminopenicillines <- c(ampi, amox)
|
aminopenicillins <- c(ampi, amox)
|
||||||
ureidopenicillines <- pita # eigenlijk ook azlo en mezlo
|
ureidopenicillins <- pita # should officially also be azlo and mezlo
|
||||||
fluorochinolonen <- c(oflo, cipr, norf, levo, moxi)
|
fluoroquinolones <- c(oflo, cipr, norf, levo, moxi)
|
||||||
|
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('\nApplying rules to',
|
cat(
|
||||||
|
paste0(
|
||||||
|
'\nApplying rules to ',
|
||||||
tbl[!is.na(tbl$genus),] %>% nrow() %>% format(big.mark = ","),
|
tbl[!is.na(tbl$genus),] %>% nrow() %>% format(big.mark = ","),
|
||||||
'rows according to "EUCAST Expert Rules Version 3.1"\n\n')
|
' rows according to "EUCAST Expert Rules Version ', EUCAST_VERSION, '"\n')
|
||||||
|
)
|
||||||
}
|
}
|
||||||
|
|
||||||
# Table 1: Intrinsic resistance in Enterobacteriaceae ----
|
# Table 1: Intrinsic resistance in Enterobacteriaceae ----
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 1: Intrinsic resistance in Enterobacteriaceae\n')
|
cat('...Table 1: Intrinsic resistance in Enterobacteriaceae\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(17)
|
# Intrisiek R for this group
|
||||||
# Intrisiek R voor groep
|
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$family == 'Enterobacteriaceae'),
|
rows = which(tbl$family == 'Enterobacteriaceae'),
|
||||||
cols = c(peni, glycopeptiden, fusi, macroliden, linc, streptogramines, rifa, dapt, line))
|
cols = c(peni, glycopeptides, fusi, macrolides, linc, streptogramins, rifa, dapt, line))
|
||||||
# Citrobacter
|
# Citrobacter
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)'),
|
rows = which(tbl$fullname %like% '^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)'),
|
||||||
cols = c(aminopenicillines, tica))
|
cols = c(aminopenicillins, tica))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)'),
|
rows = which(tbl$fullname %like% '^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfox))
|
cols = c(aminopenicillins, amcl, czol, cfox))
|
||||||
# Enterobacter
|
# Enterobacter
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Enterobacter cloacae'),
|
rows = which(tbl$fullname %like% '^Enterobacter cloacae'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfox))
|
cols = c(aminopenicillins, amcl, czol, cfox))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Enterobacter aerogenes'),
|
rows = which(tbl$fullname %like% '^Enterobacter aerogenes'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfox))
|
cols = c(aminopenicillins, amcl, czol, cfox))
|
||||||
# Escherichia
|
# Escherichia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Escherichia hermanni'),
|
rows = which(tbl$fullname %like% '^Escherichia hermanni'),
|
||||||
cols = c(aminopenicillines, tica))
|
cols = c(aminopenicillins, tica))
|
||||||
# Hafnia
|
# Hafnia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Hafnia alvei'),
|
rows = which(tbl$fullname %like% '^Hafnia alvei'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfox))
|
cols = c(aminopenicillins, amcl, czol, cfox))
|
||||||
# Klebsiella
|
# Klebsiella
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Klebsiella'),
|
rows = which(tbl$fullname %like% '^Klebsiella'),
|
||||||
cols = c(aminopenicillines, tica))
|
cols = c(aminopenicillins, tica))
|
||||||
# Morganella / Proteus
|
# Morganella / Proteus
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Morganella morganii'),
|
rows = which(tbl$fullname %like% '^Morganella morganii'),
|
||||||
cols = c(aminopenicillines, amcl, czol, tetracyclines, polymyxines, nitr))
|
cols = c(aminopenicillins, amcl, czol, tetracyclines, polymyxins, nitr))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Proteus mirabilis'),
|
rows = which(tbl$fullname %like% '^Proteus mirabilis'),
|
||||||
cols = c(tetracyclines, tige, polymyxines, nitr))
|
cols = c(tetracyclines, tige, polymyxins, nitr))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Proteus penneri'),
|
rows = which(tbl$fullname %like% '^Proteus penneri'),
|
||||||
cols = c(aminopenicillines, czol, cfur, tetracyclines, tige, polymyxines, nitr))
|
cols = c(aminopenicillins, czol, cfur, tetracyclines, tige, polymyxins, nitr))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Proteus vulgaris'),
|
rows = which(tbl$fullname %like% '^Proteus vulgaris'),
|
||||||
cols = c(aminopenicillines, czol, cfur, tetracyclines, tige, polymyxines, nitr))
|
cols = c(aminopenicillins, czol, cfur, tetracyclines, tige, polymyxins, nitr))
|
||||||
# Providencia
|
# Providencia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Providencia rettgeri'),
|
rows = which(tbl$fullname %like% '^Providencia rettgeri'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfur, tetracyclines, tige, polymyxines, nitr))
|
cols = c(aminopenicillins, amcl, czol, cfur, tetracyclines, tige, polymyxins, nitr))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Providencia stuartii'),
|
rows = which(tbl$fullname %like% '^Providencia stuartii'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfur, tetracyclines, tige, polymyxines, nitr))
|
cols = c(aminopenicillins, amcl, czol, cfur, tetracyclines, tige, polymyxins, nitr))
|
||||||
# Raoultella
|
# Raoultella
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Raoultella'),
|
rows = which(tbl$fullname %like% '^Raoultella'),
|
||||||
cols = c(aminopenicillines, tica))
|
cols = c(aminopenicillins, tica))
|
||||||
# Serratia
|
# Serratia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Serratia marcescens'),
|
rows = which(tbl$fullname %like% '^Serratia marcescens'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfox, cfur, tetracyclines[tetracyclines != 'mino'], polymyxines, nitr))
|
cols = c(aminopenicillins, amcl, czol, cfox, cfur, tetracyclines[tetracyclines != 'mino'], polymyxins, nitr))
|
||||||
# Yersinia
|
# Yersinia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Yersinia enterocolitica'),
|
rows = which(tbl$fullname %like% '^Yersinia enterocolitica'),
|
||||||
cols = c(aminopenicillines, amcl, tica, czol, cfox))
|
cols = c(aminopenicillins, amcl, tica, czol, cfox))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Yersinia pseudotuberculosis'),
|
rows = which(tbl$fullname %like% '^Yersinia pseudotuberculosis'),
|
||||||
cols = c(poly, coli))
|
cols = c(poly, coli))
|
||||||
@ -309,8 +384,7 @@ EUCAST_rules <- function(tbl,
|
|||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 2: Intrinsic resistance in non-fermentative Gram-negative bacteria\n')
|
cat('...Table 2: Intrinsic resistance in non-fermentative Gram-negative bacteria\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(8)
|
# Intrisiek R for this group
|
||||||
# Intrisiek R voor groep
|
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus %in% c('Achromobacter',
|
rows = which(tbl$genus %in% c('Achromobacter',
|
||||||
'Acinetobacter',
|
'Acinetobacter',
|
||||||
@ -322,54 +396,53 @@ EUCAST_rules <- function(tbl,
|
|||||||
'Ochrobactrum',
|
'Ochrobactrum',
|
||||||
'Pseudomonas',
|
'Pseudomonas',
|
||||||
'Stenotrophomonas')),
|
'Stenotrophomonas')),
|
||||||
cols = c(peni, cfox, cfur, glycopeptiden, fusi, macroliden, linc, streptogramines, rifa, dapt, line))
|
cols = c(peni, cfox, cfur, glycopeptides, fusi, macrolides, linc, streptogramins, rifa, dapt, line))
|
||||||
# Acinetobacter
|
# Acinetobacter
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Acinetobacter (baumannii|pittii|nosocomialis|calcoaceticus)'),
|
rows = which(tbl$fullname %like% '^Acinetobacter (baumannii|pittii|nosocomialis|calcoaceticus)'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfot, cftr, aztr, erta, trim, fosf, tetracyclines[tetracyclines != 'mino']))
|
cols = c(aminopenicillins, amcl, czol, cfot, cftr, aztr, erta, trim, fosf, tetracyclines[tetracyclines != 'mino']))
|
||||||
# Achromobacter
|
# Achromobacter
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Achromobacter (xylosoxydans|xylosoxidans)'),
|
rows = which(tbl$fullname %like% '^Achromobacter (xylosoxydans|xylosoxidans)'),
|
||||||
cols = c(aminopenicillines, czol, cfot, cftr, erta))
|
cols = c(aminopenicillins, czol, cfot, cftr, erta))
|
||||||
# Burkholderia
|
# Burkholderia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
# onder 'Burkholderia cepacia complex' vallen deze species allemaal: PMID 16217180.
|
# onder 'Burkholderia cepacia complex' vallen deze species allemaal: PMID 16217180.
|
||||||
rows = which(tbl$fullname %like% '^Burkholderia (cepacia|multivorans|cenocepacia|stabilis|vietnamiensis|dolosa|ambifaria|anthina|pyrrocinia|ubonensis)'),
|
rows = which(tbl$fullname %like% '^Burkholderia (cepacia|multivorans|cenocepacia|stabilis|vietnamiensis|dolosa|ambifaria|anthina|pyrrocinia|ubonensis)'),
|
||||||
cols = c(aminopenicillines, amcl, tica, pita, czol, cfot, cftr, aztr, erta, cipr, chlo, aminoglycosiden, trim, fosf, polymyxines))
|
cols = c(aminopenicillins, amcl, tica, pita, czol, cfot, cftr, aztr, erta, cipr, chlo, aminoglycosides, trim, fosf, polymyxins))
|
||||||
# Elizabethkingia
|
# Elizabethkingia
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Elizabethkingia meningoseptic(a|um)'),
|
rows = which(tbl$fullname %like% '^Elizabethkingia meningoseptic(a|um)'),
|
||||||
cols = c(aminopenicillines, amcl, tica, czol, cfot, cftr, cfta, cfep, aztr, erta, imip, mero, polymyxines))
|
cols = c(aminopenicillins, amcl, tica, czol, cfot, cftr, cfta, cfep, aztr, erta, imip, mero, polymyxins))
|
||||||
# Ochrobactrum
|
# Ochrobactrum
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Ochrobactrum anthropi'),
|
rows = which(tbl$fullname %like% '^Ochrobactrum anthropi'),
|
||||||
cols = c(aminopenicillines, amcl, tica, pita, czol, cfot, cftr, cfta, cfep, aztr, erta))
|
cols = c(aminopenicillins, amcl, tica, pita, czol, cfot, cftr, cfta, cfep, aztr, erta))
|
||||||
# Pseudomonas
|
# Pseudomonas
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Pseudomonas aeruginosa'),
|
rows = which(tbl$fullname %like% '^Pseudomonas aeruginosa'),
|
||||||
cols = c(aminopenicillines, amcl, czol, cfot, cftr, erta, chlo, kana, neom, trim, trsu, tetracyclines, tige))
|
cols = c(aminopenicillins, amcl, czol, cfot, cftr, erta, chlo, kana, neom, trim, trsu, tetracyclines, tige))
|
||||||
# Stenotrophomonas
|
# Stenotrophomonas
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Stenotrophomonas maltophilia'),
|
rows = which(tbl$fullname %like% '^Stenotrophomonas maltophilia'),
|
||||||
cols = c(aminopenicillines, amcl, tica, pita, czol, cfot, cftr, cfta, aztr, erta, imip, mero, aminoglycosiden, trim, fosf, tetr))
|
cols = c(aminopenicillins, amcl, tica, pita, czol, cfot, cftr, cfta, aztr, erta, imip, mero, aminoglycosides, trim, fosf, tetr))
|
||||||
|
|
||||||
|
|
||||||
# Table 3: Intrinsic resistance in other Gram-negative bacteria ----
|
# Table 3: Intrinsic resistance in other Gram-negative bacteria ----
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 3: Intrinsic resistance in other Gram-negative bacteria\n')
|
cat('...Table 3: Intrinsic resistance in other Gram-negative bacteria\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(7)
|
# Intrisiek R for this group
|
||||||
# Intrisiek R voor groep
|
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus %in% c('Haemophilus',
|
rows = which(tbl$genus %in% c('Haemophilus',
|
||||||
'Moraxella',
|
'Moraxella',
|
||||||
'Neisseria',
|
'Neisseria',
|
||||||
'Campylobacter')),
|
'Campylobacter')),
|
||||||
cols = c(glycopeptiden, linc, dapt, line))
|
cols = c(glycopeptides, linc, dapt, line))
|
||||||
# Haemophilus
|
# Haemophilus
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Haemophilus influenzae'),
|
rows = which(tbl$fullname %like% '^Haemophilus influenzae'),
|
||||||
cols = c(fusi, streptogramines))
|
cols = c(fusi, streptogramins))
|
||||||
# Moraxella
|
# Moraxella
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Moraxella catarrhalis'),
|
rows = which(tbl$fullname %like% '^Moraxella catarrhalis'),
|
||||||
@ -381,21 +454,20 @@ EUCAST_rules <- function(tbl,
|
|||||||
# Campylobacter
|
# Campylobacter
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Campylobacter fetus'),
|
rows = which(tbl$fullname %like% '^Campylobacter fetus'),
|
||||||
cols = c(fusi, streptogramines, trim, nali))
|
cols = c(fusi, streptogramins, trim, nali))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Campylobacter (jejuni|coli)'),
|
rows = which(tbl$fullname %like% '^Campylobacter (jejuni|coli)'),
|
||||||
cols = c(fusi, streptogramines, trim))
|
cols = c(fusi, streptogramins, trim))
|
||||||
|
|
||||||
|
|
||||||
# Table 4: Intrinsic resistance in Gram-positive bacteria ----
|
# Table 4: Intrinsic resistance in Gram-positive bacteria ----
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 4: Intrinsic resistance in Gram-positive bacteria\n')
|
cat('...Table 4: Intrinsic resistance in Gram-positive bacteria\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(14)
|
# Intrisiek R for this group
|
||||||
# Intrisiek R voor groep
|
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$gramstain %like% 'Positi(e|)(v|f)'),
|
rows = which(tbl$gramstain %like% 'Positi(e|)(v|f)'),
|
||||||
cols = c(aztr, polymyxines, nali))
|
cols = c(aztr, polymyxins, nali))
|
||||||
# Staphylococcus
|
# Staphylococcus
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Staphylococcus saprophyticus'),
|
rows = which(tbl$fullname %like% '^Staphylococcus saprophyticus'),
|
||||||
@ -412,17 +484,17 @@ EUCAST_rules <- function(tbl,
|
|||||||
# Streptococcus
|
# Streptococcus
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Streptococcus'),
|
rows = which(tbl$genus == 'Streptococcus'),
|
||||||
cols = c(fusi, cfta, aminoglycosiden))
|
cols = c(fusi, cfta, aminoglycosides))
|
||||||
# Enterococcus
|
# Enterococcus
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Enterococcus faecalis'),
|
rows = which(tbl$fullname %like% '^Enterococcus faecalis'),
|
||||||
cols = c(fusi, cfta, cefalosporines[cefalosporines != cfta], aminoglycosiden, macroliden, clin, qida, trim, trsu))
|
cols = c(fusi, cfta, cephalosporins[cephalosporins != cfta], aminoglycosides, macrolides, clin, qida, trim, trsu))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Enterococcus (gallinarum|casseliflavus)'),
|
rows = which(tbl$fullname %like% '^Enterococcus (gallinarum|casseliflavus)'),
|
||||||
cols = c(fusi, cfta, cefalosporines[cefalosporines != cfta], aminoglycosiden, macroliden, clin, qida, vanc, trim, trsu))
|
cols = c(fusi, cfta, cephalosporins[cephalosporins != cfta], aminoglycosides, macrolides, clin, qida, vanc, trim, trsu))
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Enterococcus faecium'),
|
rows = which(tbl$fullname %like% '^Enterococcus faecium'),
|
||||||
cols = c(fusi, cfta, cefalosporines[cefalosporines != cfta], aminoglycosiden, macroliden, trim, trsu))
|
cols = c(fusi, cfta, cephalosporins[cephalosporins != cfta], aminoglycosides, macrolides, trim, trsu))
|
||||||
# Corynebacterium
|
# Corynebacterium
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Corynebacterium'),
|
rows = which(tbl$genus == 'Corynebacterium'),
|
||||||
@ -430,7 +502,7 @@ EUCAST_rules <- function(tbl,
|
|||||||
# Listeria
|
# Listeria
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Listeria monocytogenes'),
|
rows = which(tbl$fullname %like% '^Listeria monocytogenes'),
|
||||||
cols = c(cfta, cefalosporines[cefalosporines != cfta]))
|
cols = c(cfta, cephalosporins[cephalosporins != cfta]))
|
||||||
# overig
|
# overig
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus %in% c('Leuconostoc', 'Pediococcus')),
|
rows = which(tbl$genus %in% c('Leuconostoc', 'Pediococcus')),
|
||||||
@ -446,34 +518,32 @@ EUCAST_rules <- function(tbl,
|
|||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 8: Interpretive rules for B-lactam agents and Gram-positive cocci\n')
|
cat('...Table 8: Interpretive rules for B-lactam agents and Gram-positive cocci\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(2)
|
# rule 8.3
|
||||||
# regel 8.3
|
|
||||||
if (!is.na(peni)) {
|
if (!is.na(peni)) {
|
||||||
edit_rsi(to = 'S',
|
edit_rsi(to = 'S',
|
||||||
rows = which(tbl$fullname %like% '^Streptococcus (pyogenes|agalactiae|dysgalactiae|groep A|groep B|groep C|groep G)'
|
rows = which(tbl$fullname %like% '^Streptococcus (pyogenes|agalactiae|dysgalactiae|groep A|groep B|groep C|groep G)'
|
||||||
& tbl[, peni] == 'S'),
|
& tbl[, peni] == 'S'),
|
||||||
cols = c(aminopenicillines, cefalosporines, carbapenems))
|
cols = c(aminopenicillins, cephalosporins, carbapenems))
|
||||||
}
|
}
|
||||||
# regel 8.6
|
# rule 8.6
|
||||||
if (!is.na(ampi)) {
|
if (!is.na(ampi)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Enterococcus'
|
rows = which(tbl$genus == 'Enterococcus'
|
||||||
& tbl[, ampi] == 'R'),
|
& tbl[, ampi] == 'R'),
|
||||||
cols = c(ureidopenicillines, carbapenems))
|
cols = c(ureidopenicillins, carbapenems))
|
||||||
}
|
}
|
||||||
if (!is.na(amox)) {
|
if (!is.na(amox)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Enterococcus'
|
rows = which(tbl$genus == 'Enterococcus'
|
||||||
& tbl[, amox] == 'R'),
|
& tbl[, amox] == 'R'),
|
||||||
cols = c(ureidopenicillines, carbapenems))
|
cols = c(ureidopenicillins, carbapenems))
|
||||||
}
|
}
|
||||||
|
|
||||||
# Table 9: Interpretive rules for B-lactam agents and Gram-negative rods ----
|
# Table 9: Interpretive rules for B-lactam agents and Gram-negative rods ----
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 9: Interpretive rules for B-lactam agents and Gram-negative rods\n')
|
cat('...Table 9: Interpretive rules for B-lactam agents and Gram-negative rods\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(1)
|
# rule 9.3
|
||||||
# regel 9.3
|
|
||||||
if (!is.na(tica) & !is.na(pita)) {
|
if (!is.na(tica) & !is.na(pita)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$family == 'Enterobacteriaceae'
|
rows = which(tbl$family == 'Enterobacteriaceae'
|
||||||
@ -486,10 +556,9 @@ EUCAST_rules <- function(tbl,
|
|||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 10: Interpretive rules for B-lactam agents and other Gram-negative bacteria\n')
|
cat('...Table 10: Interpretive rules for B-lactam agents and other Gram-negative bacteria\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(1)
|
# rule 10.2
|
||||||
# regel 10.2
|
|
||||||
if (!is.na(ampi)) {
|
if (!is.na(ampi)) {
|
||||||
# hiervoor moeten we eerst weten of ze B-lactamase-positief zijn
|
# you should know first if the are B-lactamase positive, so do not run for now
|
||||||
# edit_rsi(to = 'R',
|
# edit_rsi(to = 'R',
|
||||||
# rows = which(tbl$fullname %like% '^Haemophilus influenza'
|
# rows = which(tbl$fullname %like% '^Haemophilus influenza'
|
||||||
# & tbl[, ampi] == 'R'),
|
# & tbl[, ampi] == 'R'),
|
||||||
@ -500,7 +569,7 @@ EUCAST_rules <- function(tbl,
|
|||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins\n')
|
cat('...Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins\n')
|
||||||
}
|
}
|
||||||
# regel 11.1
|
# rule 11.1
|
||||||
if (!is.na(eryt)) {
|
if (!is.na(eryt)) {
|
||||||
if (!is.na(azit)) {
|
if (!is.na(azit)) {
|
||||||
tbl[, azit] <- tbl[, eryt]
|
tbl[, azit] <- tbl[, eryt]
|
||||||
@ -514,22 +583,21 @@ EUCAST_rules <- function(tbl,
|
|||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 12: Interpretive rules for aminoglycosides\n')
|
cat('...Table 12: Interpretive rules for aminoglycosides\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(4)
|
# rule 12.2
|
||||||
# regel 12.2
|
|
||||||
if (!is.na(tobr)) {
|
if (!is.na(tobr)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Staphylococcus'
|
rows = which(tbl$genus == 'Staphylococcus'
|
||||||
& tbl[, tobr] == 'R'),
|
& tbl[, tobr] == 'R'),
|
||||||
cols = c(kana, amik))
|
cols = c(kana, amik))
|
||||||
}
|
}
|
||||||
# regel 12.3
|
# rule 12.3
|
||||||
if (!is.na(gent)) {
|
if (!is.na(gent)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Staphylococcus'
|
rows = which(tbl$genus == 'Staphylococcus'
|
||||||
& tbl[, gent] == 'R'),
|
& tbl[, gent] == 'R'),
|
||||||
cols = aminoglycosiden)
|
cols = aminoglycosides)
|
||||||
}
|
}
|
||||||
# regel 12.8
|
# rule 12.8
|
||||||
if (!is.na(gent) & !is.na(tobr)) {
|
if (!is.na(gent) & !is.na(tobr)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$family == 'Enterobacteriaceae'
|
rows = which(tbl$family == 'Enterobacteriaceae'
|
||||||
@ -537,7 +605,7 @@ EUCAST_rules <- function(tbl,
|
|||||||
& tbl[, tobr] == 'S'),
|
& tbl[, tobr] == 'S'),
|
||||||
cols = gent)
|
cols = gent)
|
||||||
}
|
}
|
||||||
# regel 12.9
|
# rule 12.9
|
||||||
if (!is.na(gent) & !is.na(tobr)) {
|
if (!is.na(gent) & !is.na(tobr)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$family == 'Enterobacteriaceae'
|
rows = which(tbl$family == 'Enterobacteriaceae'
|
||||||
@ -551,42 +619,40 @@ EUCAST_rules <- function(tbl,
|
|||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Table 13: Interpretive rules for quinolones\n')
|
cat('...Table 13: Interpretive rules for quinolones\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(4)
|
# rule 13.2
|
||||||
# regel 13.2
|
|
||||||
if (!is.na(moxi)) {
|
if (!is.na(moxi)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$genus == 'Staphylococcus'
|
rows = which(tbl$genus == 'Staphylococcus'
|
||||||
& tbl[, moxi] == 'R'),
|
& tbl[, moxi] == 'R'),
|
||||||
cols = fluorochinolonen)
|
cols = fluoroquinolones)
|
||||||
}
|
}
|
||||||
# regel 13.4
|
# rule 13.4
|
||||||
if (!is.na(moxi)) {
|
if (!is.na(moxi)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Streptococcus pneumoniae'
|
rows = which(tbl$fullname %like% '^Streptococcus pneumoniae'
|
||||||
& tbl[, moxi] == 'R'),
|
& tbl[, moxi] == 'R'),
|
||||||
cols = fluorochinolonen)
|
cols = fluoroquinolones)
|
||||||
}
|
}
|
||||||
# regel 13.5
|
# rule 13.5
|
||||||
if (!is.na(cipr)) {
|
if (!is.na(cipr)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$family == 'Enterobacteriaceae'
|
rows = which(tbl$family == 'Enterobacteriaceae'
|
||||||
& tbl[, cipr] == 'R'),
|
& tbl[, cipr] == 'R'),
|
||||||
cols = fluorochinolonen)
|
cols = fluoroquinolones)
|
||||||
}
|
}
|
||||||
# regel 13.8
|
# rule 13.8
|
||||||
if (!is.na(cipr)) {
|
if (!is.na(cipr)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl$fullname %like% '^Neisseria gonorrhoeae'
|
rows = which(tbl$fullname %like% '^Neisseria gonorrhoeae'
|
||||||
& tbl[, cipr] == 'R'),
|
& tbl[, cipr] == 'R'),
|
||||||
cols = fluorochinolonen)
|
cols = fluoroquinolones)
|
||||||
}
|
}
|
||||||
|
|
||||||
|
|
||||||
# Other ----
|
# Other ----
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('...Other\n')
|
cat('...Non-EUCAST: trim = R where trsu = R and ampi = R where amcl = R\n')
|
||||||
}
|
}
|
||||||
#voortgang <- progress_estimated(2)
|
|
||||||
if (!is.na(amcl)) {
|
if (!is.na(amcl)) {
|
||||||
edit_rsi(to = 'R',
|
edit_rsi(to = 'R',
|
||||||
rows = which(tbl[, amcl] == 'R'),
|
rows = which(tbl[, amcl] == 'R'),
|
||||||
@ -601,17 +667,17 @@ EUCAST_rules <- function(tbl,
|
|||||||
tbl[, amox] <- tbl %>% pull(ampi)
|
tbl[, amox] <- tbl %>% pull(ampi)
|
||||||
}
|
}
|
||||||
|
|
||||||
# Toegevoegde kolommen weer verwijderen
|
# Remove added columns again
|
||||||
bactlist.ncol <- ncol(AMR::bactlist) - 2
|
microorganisms.ncol <- ncol(AMR::microorganisms) - 2
|
||||||
tbl.ncol <- ncol(tbl)
|
tbl.ncol <- ncol(tbl)
|
||||||
tbl <- tbl %>% select(-c((tbl.ncol - bactlist.ncol):tbl.ncol))
|
tbl <- tbl %>% select(-c((tbl.ncol - microorganisms.ncol):tbl.ncol))
|
||||||
# en eventueel toegevoegde suffix aan bestaande kolommen weer verwijderen
|
# and remove added suffices
|
||||||
colnames(tbl) <- gsub("_tempbactlist", "", colnames(tbl))
|
colnames(tbl) <- gsub("_tempmicroorganisms", "", colnames(tbl))
|
||||||
|
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('\nDone.\nEUCAST Expert rules applied to',
|
cat('Done.\n\nEUCAST Expert rules applied to',
|
||||||
total_rows %>% unique() %>% length() %>% format(big.mark = ","),
|
total_rows %>% unique() %>% length() %>% format(big.mark = ","),
|
||||||
'different rows, to a total of',
|
'different rows (isolates); edited a total of',
|
||||||
total %>% format(big.mark = ","), 'test results.\n\n')
|
total %>% format(big.mark = ","), 'test results.\n\n')
|
||||||
}
|
}
|
||||||
|
|
||||||
@ -626,14 +692,14 @@ interpretive_reading <- function(...) {
|
|||||||
|
|
||||||
#' Poperties of a microorganism
|
#' Poperties of a microorganism
|
||||||
#'
|
#'
|
||||||
#' @param bactcode ID of a microorganisme, like \code{"STAAUR} and \code{"ESCCOL}
|
#' @param bactid ID of a microorganisme, like \code{"STAAUR} and \code{"ESCCOL}
|
||||||
#' @param property One of the values \code{bactid}, \code{bactsys}, \code{family}, \code{genus}, \code{species}, \code{subspecies}, \code{fullname}, \code{type}, \code{gramstain}, \code{aerobic}
|
#' @param property One of the values \code{bactid}, \code{bactsys}, \code{family}, \code{genus}, \code{species}, \code{subspecies}, \code{fullname}, \code{type}, \code{gramstain}, \code{aerobic}
|
||||||
#' @export
|
#' @export
|
||||||
#' @importFrom dplyr %>% filter select
|
#' @importFrom dplyr %>% filter select
|
||||||
#' @seealso \code{\link{bactlist}}
|
#' @seealso \code{\link{microorganisms}}
|
||||||
mo_property <- function(bactcode, property = 'fullname') {
|
mo_property <- function(bactid, property = 'fullname') {
|
||||||
|
|
||||||
mocode <- as.character(bactcode)
|
mocode <- as.character(bactid)
|
||||||
|
|
||||||
for (i in 1:length(mocode)) {
|
for (i in 1:length(mocode)) {
|
||||||
bug <- mocode[i]
|
bug <- mocode[i]
|
||||||
@ -641,8 +707,8 @@ mo_property <- function(bactcode, property = 'fullname') {
|
|||||||
if (!is.na(bug)) {
|
if (!is.na(bug)) {
|
||||||
result = tryCatch({
|
result = tryCatch({
|
||||||
mocode[i] <-
|
mocode[i] <-
|
||||||
AMR::bactlist %>%
|
AMR::microorganisms %>%
|
||||||
filter(bactid == bactcode) %>%
|
filter(bactid == bactid) %>%
|
||||||
select(property) %>%
|
select(property) %>%
|
||||||
unlist() %>%
|
unlist() %>%
|
||||||
as.character()
|
as.character()
|
||||||
|
25
R/atc.R
25
R/atc.R
@ -129,7 +129,7 @@ atc_property <- function(atc_code,
|
|||||||
#'
|
#'
|
||||||
#' Convert antibiotic codes (from a laboratory information system like MOLIS or GLIMS) to a (trivial) antibiotic name or ATC code, or vice versa. This uses the data from \code{\link{antibiotics}}.
|
#' Convert antibiotic codes (from a laboratory information system like MOLIS or GLIMS) to a (trivial) antibiotic name or ATC code, or vice versa. This uses the data from \code{\link{antibiotics}}.
|
||||||
#' @param abcode a code or name, like \code{"AMOX"}, \code{"AMCL"} or \code{"J01CA04"}
|
#' @param abcode a code or name, like \code{"AMOX"}, \code{"AMCL"} or \code{"J01CA04"}
|
||||||
#' @param from,to type to transform from and to. See \code{\link{antibiotics}} for its column names.
|
#' @param from,to type to transform from and to. See \code{\link{antibiotics}} for its column names. WIth \code{from = "guess"} the from will be guessed from \code{"atc"}, \code{"molis"} and \code{"umcg"}.
|
||||||
#' @param textbetween text to put between multiple returned texts
|
#' @param textbetween text to put between multiple returned texts
|
||||||
#' @param tolower return output as lower case with function \code{\link{tolower}}.
|
#' @param tolower return output as lower case with function \code{\link{tolower}}.
|
||||||
#' @keywords ab antibiotics
|
#' @keywords ab antibiotics
|
||||||
@ -154,9 +154,22 @@ atc_property <- function(atc_code,
|
|||||||
#'
|
#'
|
||||||
#' abname("J01CR02", from = "atc", to = "umcg")
|
#' abname("J01CR02", from = "atc", to = "umcg")
|
||||||
#' # "AMCL"
|
#' # "AMCL"
|
||||||
abname <- function(abcode, from = 'umcg', to = 'official', textbetween = ' + ', tolower = FALSE) {
|
abname <- function(abcode, from = c("guess", "atc", "molis", "umcg"), to = 'official', textbetween = ' + ', tolower = FALSE) {
|
||||||
|
|
||||||
antibiotics <- AMR::antibiotics
|
antibiotics <- AMR::antibiotics
|
||||||
|
|
||||||
|
from <- from[1]
|
||||||
|
if (from == "guess") {
|
||||||
|
for (i in 1:3) {
|
||||||
|
if (abcode[1] %in% (antibiotics %>% pull(i))) {
|
||||||
|
from <- colnames(antibiotics)[i]
|
||||||
|
}
|
||||||
|
}
|
||||||
|
if (from == "guess") {
|
||||||
|
from <- "umcg"
|
||||||
|
}
|
||||||
|
}
|
||||||
|
|
||||||
colnames(antibiotics) <- colnames(antibiotics) %>% tolower()
|
colnames(antibiotics) <- colnames(antibiotics) %>% tolower()
|
||||||
from <- from %>% tolower()
|
from <- from %>% tolower()
|
||||||
to <- to %>% tolower()
|
to <- to %>% tolower()
|
||||||
@ -172,8 +185,8 @@ abname <- function(abcode, from = 'umcg', to = 'official', textbetween = ' + ',
|
|||||||
for (i in 1:length(abcode)) {
|
for (i in 1:length(abcode)) {
|
||||||
drug <- abcode[i]
|
drug <- abcode[i]
|
||||||
if (!grepl('+', drug, fixed = TRUE) & !grepl(' en ', drug, fixed = TRUE)) {
|
if (!grepl('+', drug, fixed = TRUE) & !grepl(' en ', drug, fixed = TRUE)) {
|
||||||
# bestaat maar uit 1 middel
|
# only 1 drug
|
||||||
if (any(antibiotics[, from] == drug)) {
|
if (drug %in% (antibiotics %>% pull(from))) {
|
||||||
abcode[i] <-
|
abcode[i] <-
|
||||||
antibiotics %>%
|
antibiotics %>%
|
||||||
filter(.[, from] == drug) %>%
|
filter(.[, from] == drug) %>%
|
||||||
@ -181,12 +194,12 @@ abname <- function(abcode, from = 'umcg', to = 'official', textbetween = ' + ',
|
|||||||
slice(1) %>%
|
slice(1) %>%
|
||||||
as.character()
|
as.character()
|
||||||
} else {
|
} else {
|
||||||
# niet gevonden
|
# not found
|
||||||
warning('Code "', drug, '" not found in antibiotics list.', call. = FALSE)
|
warning('Code "', drug, '" not found in antibiotics list.', call. = FALSE)
|
||||||
abcode[i] <- NA
|
abcode[i] <- NA
|
||||||
}
|
}
|
||||||
} else {
|
} else {
|
||||||
# meerdere middelen
|
# more than 1 drug
|
||||||
if (grepl('+', drug, fixed = TRUE)) {
|
if (grepl('+', drug, fixed = TRUE)) {
|
||||||
drug.group <-
|
drug.group <-
|
||||||
strsplit(drug, '+', fixed = TRUE) %>%
|
strsplit(drug, '+', fixed = TRUE) %>%
|
||||||
|
84
R/clipboard.R
Normal file
84
R/clipboard.R
Normal file
@ -0,0 +1,84 @@
|
|||||||
|
#' Import/export from clipboard
|
||||||
|
#'
|
||||||
|
#' These are helper functions around \code{\link{read.table}} and \code{\link{write.table}} to import from and export to clipboard. The data will be read and written as tab-separated by default, which makes it possible to copy and paste from other software like Excel and SPSS without further transformation.
|
||||||
|
#' @rdname clipboard
|
||||||
|
#' @name clipboard
|
||||||
|
#' @inheritParams utils::read.table
|
||||||
|
#' @inheritParams utils::write.table
|
||||||
|
#' @param startrow \emph{n}th row to start importing from. For \code{clipboard_import}, when \code{header = TRUE} the import will start on row \code{startrow} \emph{below} the header.
|
||||||
|
#' @param as_vector a logical value indicating whether data consisting of only one column should be imported as vector using \code{\link[dplyr]{pull}}. This will strip off the header.
|
||||||
|
#' @keywords clipboard clipboard_import clipboard_export import export
|
||||||
|
#' @importFrom dplyr %>% pull as_tibble
|
||||||
|
#' @importFrom utils read.delim write.table object.size writeClipboard
|
||||||
|
#' @details For \code{clipboard_export}, the reserved clipboard size for exporting will be set automatically to 125\% of the object size of \code{x}. This way, it is possible to export data with thousands of rows as the only limit will be your systems RAM.
|
||||||
|
#' @export
|
||||||
|
#' @return data.frame
|
||||||
|
clipboard_import <- function(sep = '\t',
|
||||||
|
header = TRUE,
|
||||||
|
dec = ".",
|
||||||
|
na = c("", "NA", "NULL"),
|
||||||
|
startrow = 1,
|
||||||
|
as_vector = TRUE) {
|
||||||
|
|
||||||
|
import_tbl <- read.delim(file = 'clipboard',
|
||||||
|
sep = sep,
|
||||||
|
header = header,
|
||||||
|
strip.white = TRUE,
|
||||||
|
dec = dec,
|
||||||
|
na.strings = na,
|
||||||
|
fileEncoding = 'UTF-8',
|
||||||
|
encoding = 'UTF-8',
|
||||||
|
stringsAsFactors = FALSE)
|
||||||
|
|
||||||
|
# use tibble, so column types will be translated correctly
|
||||||
|
import_tbl <- as_tibble(import_tbl)
|
||||||
|
|
||||||
|
if (startrow > 1) {
|
||||||
|
# would else lose column headers
|
||||||
|
import_tbl <- import_tbl[startrow:nrow(import_tbl),]
|
||||||
|
}
|
||||||
|
|
||||||
|
colnames(import_tbl) <- gsub('[.]+', '_', colnames(import_tbl))
|
||||||
|
|
||||||
|
if (NCOL(import_tbl) == 1 & as_vector == TRUE) {
|
||||||
|
import_tbl %>% pull(1)
|
||||||
|
} else {
|
||||||
|
import_tbl
|
||||||
|
}
|
||||||
|
}
|
||||||
|
|
||||||
|
#' @rdname clipboard
|
||||||
|
#' @importFrom dplyr %>% pull as_tibble
|
||||||
|
#' @export
|
||||||
|
clipboard_export <- function(x,
|
||||||
|
sep = '\t',
|
||||||
|
dec = ".",
|
||||||
|
na = "",
|
||||||
|
header = TRUE) {
|
||||||
|
|
||||||
|
x <- deparse(substitute(x))
|
||||||
|
size <- x %>%
|
||||||
|
get() %>%
|
||||||
|
object.size() %>%
|
||||||
|
formatC(format = 'd') %>%
|
||||||
|
as.integer()
|
||||||
|
|
||||||
|
x <- get(x)
|
||||||
|
|
||||||
|
if (size > 25 * 1024 * 1024) {
|
||||||
|
# above 25 MB use a hacker function
|
||||||
|
writeClipboard(knitr::kable(x))
|
||||||
|
} else {
|
||||||
|
# set size of clipboard to 125% of the object size of x
|
||||||
|
write.table(x = x,
|
||||||
|
file = paste0("clipboard-", size * 1.25),
|
||||||
|
sep = sep,
|
||||||
|
na = na,
|
||||||
|
row.names = FALSE,
|
||||||
|
col.names = header,
|
||||||
|
dec = dec,
|
||||||
|
quote = FALSE)
|
||||||
|
}
|
||||||
|
cat("Successfully exported to clipboard:", NROW(x), "obs. of", NCOL(x), "variables.\n")
|
||||||
|
|
||||||
|
}
|
61
R/data.R
61
R/data.R
@ -39,7 +39,7 @@
|
|||||||
#' \item{\code{useful_grampositive}}{\code{FALSE} if not useful according to EUCAST, \code{NA} otherwise (see Source)}
|
#' \item{\code{useful_grampositive}}{\code{FALSE} if not useful according to EUCAST, \code{NA} otherwise (see Source)}
|
||||||
#' }
|
#' }
|
||||||
#' @source - World Health Organization: \url{https://www.whocc.no/atc_ddd_index/} \cr - EUCAST - Expert rules intrinsic exceptional V3.1 \cr - MOLIS (LIS of Certe): \url{https://www.certe.nl} \cr - GLIMS (LIS of UMCG): \url{https://www.umcg.nl}
|
#' @source - World Health Organization: \url{https://www.whocc.no/atc_ddd_index/} \cr - EUCAST - Expert rules intrinsic exceptional V3.1 \cr - MOLIS (LIS of Certe): \url{https://www.certe.nl} \cr - GLIMS (LIS of UMCG): \url{https://www.umcg.nl}
|
||||||
#' @seealso \code{\link{bactlist}}
|
#' @seealso \code{\link{microorganisms}}
|
||||||
# last two columns created with:
|
# last two columns created with:
|
||||||
# antibiotics %>%
|
# antibiotics %>%
|
||||||
# mutate(useful_gramnegative =
|
# mutate(useful_gramnegative =
|
||||||
@ -63,7 +63,7 @@
|
|||||||
|
|
||||||
#' Dataset with ~2500 microorganisms
|
#' Dataset with ~2500 microorganisms
|
||||||
#'
|
#'
|
||||||
#' A dataset containing all microorganisms of MOLIS. MO codes of the UMCG can be looked up using \code{\link{bactlist.umcg}}.
|
#' A dataset containing 2500 microorganisms. MO codes of the UMCG can be looked up using \code{\link{microorganisms.umcg}}.
|
||||||
#' @format A data.frame with 2507 observations and 12 variables:
|
#' @format A data.frame with 2507 observations and 12 variables:
|
||||||
#' \describe{
|
#' \describe{
|
||||||
#' \item{\code{bactid}}{ID of microorganism}
|
#' \item{\code{bactid}}{ID of microorganism}
|
||||||
@ -80,24 +80,24 @@
|
|||||||
#' \item{\code{gramstain_nl}}{Gram of microorganism in Dutch, like \code{"Negatieve staven"}}
|
#' \item{\code{gramstain_nl}}{Gram of microorganism in Dutch, like \code{"Negatieve staven"}}
|
||||||
#' }
|
#' }
|
||||||
#' @source MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
#' @source MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
||||||
#' @seealso \code{\link{guess_bactid}} \code{\link{antibiotics}} \code{\link{bactlist.umcg}}
|
#' @seealso \code{\link{guess_bactid}} \code{\link{antibiotics}} \code{\link{microorganisms.umcg}}
|
||||||
"bactlist"
|
"microorganisms"
|
||||||
|
|
||||||
#' Translation table for UMCG with ~1100 microorganisms
|
#' Translation table for UMCG with ~1100 microorganisms
|
||||||
#'
|
#'
|
||||||
#' A dataset containing all bacteria codes of UMCG MMB. These codes can be joined to data with an ID from \code{\link{bactlist}$bactid} (using \code{\link{left_join_bactlist}}). GLIMS codes can also be translated to valid \code{bactid}'s with \code{\link{guess_bactid}}.
|
#' A dataset containing all bacteria codes of UMCG MMB. These codes can be joined to data with an ID from \code{\link{microorganisms}$bactid} (using \code{\link{left_join_microorganisms}}). GLIMS codes can also be translated to valid \code{bactid}'s with \code{\link{guess_bactid}}.
|
||||||
#' @format A data.frame with 1090 observations and 2 variables:
|
#' @format A data.frame with 1090 observations and 2 variables:
|
||||||
#' \describe{
|
#' \describe{
|
||||||
#' \item{\code{mocode}}{Code of microorganism according to UMCG MMB}
|
#' \item{\code{mocode}}{Code of microorganism according to UMCG MMB}
|
||||||
#' \item{\code{bactid}}{Code of microorganism in \code{\link{bactlist}}}
|
#' \item{\code{bactid}}{Code of microorganism in \code{\link{microorganisms}}}
|
||||||
#' }
|
#' }
|
||||||
#' @source MOLIS (LIS of Certe) - \url{https://www.certe.nl} \cr \cr GLIMS (LIS of UMCG) - \url{https://www.umcg.nl}
|
#' @source MOLIS (LIS of Certe) - \url{https://www.certe.nl} \cr \cr GLIMS (LIS of UMCG) - \url{https://www.umcg.nl}
|
||||||
#' @seealso \code{\link{guess_bactid}} \code{\link{bactlist}}
|
#' @seealso \code{\link{guess_bactid}} \code{\link{microorganisms}}
|
||||||
"bactlist.umcg"
|
"microorganisms.umcg"
|
||||||
|
|
||||||
#' Dataset with 2000 blood culture isolates of septic patients
|
#' Dataset with 2000 blood culture isolates of septic patients
|
||||||
#'
|
#'
|
||||||
#' An anonymised dataset containing 2000 microbial blood culture isolates with their antibiogram of septic patients found in 5 different hospitals in the Netherlands, between 2001 and 2017. This data.frame can be used to practice AMR analysis e.g. with \code{\link{rsi}} or \code{\link{rsi_predict}}, or it can be used to practice other statistics.
|
#' An anonymised dataset containing 2000 microbial blood culture isolates with their antibiogram of septic patients found in 5 different hospitals in the Netherlands, between 2001 and 2017. This data.frame can be used to practice AMR analysis. For examples, press F1.
|
||||||
#' @format A data.frame with 2000 observations and 47 variables:
|
#' @format A data.frame with 2000 observations and 47 variables:
|
||||||
#' \describe{
|
#' \describe{
|
||||||
#' \item{\code{date}}{date of receipt at the laboratory}
|
#' \item{\code{date}}{date of receipt at the laboratory}
|
||||||
@ -108,8 +108,47 @@
|
|||||||
#' \item{\code{age}}{age of the patient}
|
#' \item{\code{age}}{age of the patient}
|
||||||
#' \item{\code{sex}}{sex of the patient}
|
#' \item{\code{sex}}{sex of the patient}
|
||||||
#' \item{\code{patient_id}}{ID of the patient, first 10 characters of an SHA hash containing irretrievable information}
|
#' \item{\code{patient_id}}{ID of the patient, first 10 characters of an SHA hash containing irretrievable information}
|
||||||
#' \item{\code{bactid}}{ID of microorganism, see \code{\link{bactlist}}}
|
#' \item{\code{bactid}}{ID of microorganism, see \code{\link{microorganisms}}}
|
||||||
#' \item{\code{peni:mupi}}{38 different antibiotics with class \code{rsi} (see \code{\link{as.rsi}}), these column names occur in \code{\link{antibiotics}} and can be translated with \code{\link{abname}}}
|
#' \item{\code{peni:mupi}}{38 different antibiotics with class \code{rsi} (see \code{\link{as.rsi}}); these column names occur in \code{\link{antibiotics}} and can be translated with \code{\link{abname}}}
|
||||||
#' }
|
#' }
|
||||||
#' @source MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
#' @source MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
||||||
|
#' @examples
|
||||||
|
#' # ----------- #
|
||||||
|
#' # PREPARATION #
|
||||||
|
#' # ----------- #
|
||||||
|
#'
|
||||||
|
#' # Save this example dataset to an object, so we can edit it:
|
||||||
|
#' my_data <- septic_patients
|
||||||
|
#'
|
||||||
|
#' # load the dplyr package to make data science A LOT easier
|
||||||
|
#' library(dplyr)
|
||||||
|
#'
|
||||||
|
#' # Add first isolates to our dataset:
|
||||||
|
#' my_data <- my_data %>%
|
||||||
|
#' mutate(first_isolates = first_isolate(my_data, date, patient_id, bactid))
|
||||||
|
#'
|
||||||
|
#' # -------- #
|
||||||
|
#' # ANALYSIS #
|
||||||
|
#' # -------- #
|
||||||
|
#'
|
||||||
|
#' # 1. Get the amoxicillin resistance percentages
|
||||||
|
#' # of E. coli, divided by hospital:
|
||||||
|
#'
|
||||||
|
#' my_data %>%
|
||||||
|
#' filter(bactid == "ESCCOL",
|
||||||
|
#' first_isolates == TRUE) %>%
|
||||||
|
#' group_by(hospital_id) %>%
|
||||||
|
#' summarise(n = n(),
|
||||||
|
#' amoxicillin_resistance = rsi(amox))
|
||||||
|
#'
|
||||||
|
#'
|
||||||
|
#' # 2. Get the amoxicillin/clavulanic acid resistance
|
||||||
|
#' # percentages of E. coli, trend over the years:
|
||||||
|
#'
|
||||||
|
#' my_data %>%
|
||||||
|
#' filter(bactid == guess_bactid("E. coli"),
|
||||||
|
#' first_isolates == TRUE) %>%
|
||||||
|
#' group_by(year = format(date, "%Y")) %>%
|
||||||
|
#' summarise(n = n(),
|
||||||
|
#' amoxclav_resistance = rsi(amcl, minimum = 20))
|
||||||
"septic_patients"
|
"septic_patients"
|
||||||
|
@ -22,8 +22,7 @@
|
|||||||
#' @param tbl a \code{data.frame} containing isolates.
|
#' @param tbl a \code{data.frame} containing isolates.
|
||||||
#' @param col_date column name of the result date (or date that is was received on the lab), supports tidyverse-like quotation
|
#' @param col_date column name of the result date (or date that is was received on the lab), supports tidyverse-like quotation
|
||||||
#' @param col_patient_id column name of the unique IDs of the patients, supports tidyverse-like quotation
|
#' @param col_patient_id column name of the unique IDs of the patients, supports tidyverse-like quotation
|
||||||
#' @param col_genus column name of the genus of the microorganisms, supports tidyverse-like quotation
|
#' @param col_bactid column name of the unique IDs of the microorganisms (should occur in the \code{\link{microorganisms}} dataset), supports tidyverse-like quotation
|
||||||
#' @param col_species column name of the species of the microorganisms, supports tidyverse-like quotation
|
|
||||||
#' @param col_testcode column name of the test codes. Use \code{col_testcode = NA} to \strong{not} exclude certain test codes (like test codes for screening). In that case \code{testcodes_exclude} will be ignored. Supports tidyverse-like quotation.
|
#' @param col_testcode column name of the test codes. Use \code{col_testcode = NA} to \strong{not} exclude certain test codes (like test codes for screening). In that case \code{testcodes_exclude} will be ignored. Supports tidyverse-like quotation.
|
||||||
#' @param col_specimen column name of the specimen type or group, supports tidyverse-like quotation
|
#' @param col_specimen column name of the specimen type or group, supports tidyverse-like quotation
|
||||||
#' @param col_icu column name of the logicals (\code{TRUE}/\code{FALSE}) whether a ward or department is an Intensive Care Unit (ICU), supports tidyverse-like quotation
|
#' @param col_icu column name of the logicals (\code{TRUE}/\code{FALSE}) whether a ward or department is an Intensive Care Unit (ICU), supports tidyverse-like quotation
|
||||||
@ -37,6 +36,8 @@
|
|||||||
#' @param ignore_I logical to determine whether antibiotic interpretations with \code{"I"} will be ignored when \code{type = "keyantibiotics"}, see Details
|
#' @param ignore_I logical to determine whether antibiotic interpretations with \code{"I"} will be ignored when \code{type = "keyantibiotics"}, see Details
|
||||||
#' @param points_threshold points until the comparison of key antibiotics will lead to inclusion of an isolate when \code{type = "points"}, see Details
|
#' @param points_threshold points until the comparison of key antibiotics will lead to inclusion of an isolate when \code{type = "points"}, see Details
|
||||||
#' @param info print progress
|
#' @param info print progress
|
||||||
|
#' @param col_genus (deprecated, use \code{col_bactid} instead) column name of the genus of the microorganisms, supports tidyverse-like quotation
|
||||||
|
#' @param col_species (deprecated, use \code{col_bactid} instead) column name of the species of the microorganisms, supports tidyverse-like quotation
|
||||||
#' @details \strong{WHY THIS IS SO IMPORTANT} \cr
|
#' @details \strong{WHY THIS IS SO IMPORTANT} \cr
|
||||||
#' To conduct an analysis of antimicrobial resistance, you should only include the first isolate of every patient per episode \href{https://www.ncbi.nlm.nih.gov/pubmed/17304462}{[1]}. If you would not do this, you could easily get an overestimate or underestimate of the resistance of an antibiotic. Imagine that a patient was admitted with an MRSA and that it was found in 5 different blood cultures the following week. The resistance percentage of oxacillin of all \emph{S. aureus} isolates would be overestimated, because you included this MRSA more than once. It would be \href{https://en.wikipedia.org/wiki/Selection_bias}{selection bias}.
|
#' To conduct an analysis of antimicrobial resistance, you should only include the first isolate of every patient per episode \href{https://www.ncbi.nlm.nih.gov/pubmed/17304462}{[1]}. If you would not do this, you could easily get an overestimate or underestimate of the resistance of an antibiotic. Imagine that a patient was admitted with an MRSA and that it was found in 5 different blood cultures the following week. The resistance percentage of oxacillin of all \emph{S. aureus} isolates would be overestimated, because you included this MRSA more than once. It would be \href{https://en.wikipedia.org/wiki/Selection_bias}{selection bias}.
|
||||||
#'
|
#'
|
||||||
@ -56,7 +57,7 @@
|
|||||||
#'
|
#'
|
||||||
#' library(dplyr)
|
#' library(dplyr)
|
||||||
#' my_patients$first_isolate <- my_patients %>%
|
#' my_patients$first_isolate <- my_patients %>%
|
||||||
#' left_join_bactlist() %>%
|
#' left_join_microorganisms() %>%
|
||||||
#' first_isolate(col_date = date,
|
#' first_isolate(col_date = date,
|
||||||
#' col_patient_id = patient_id,
|
#' col_patient_id = patient_id,
|
||||||
#' col_genus = genus,
|
#' col_genus = genus,
|
||||||
@ -104,8 +105,7 @@
|
|||||||
first_isolate <- function(tbl,
|
first_isolate <- function(tbl,
|
||||||
col_date,
|
col_date,
|
||||||
col_patient_id,
|
col_patient_id,
|
||||||
col_genus,
|
col_bactid = NA,
|
||||||
col_species,
|
|
||||||
col_testcode = NA,
|
col_testcode = NA,
|
||||||
col_specimen = NA,
|
col_specimen = NA,
|
||||||
col_icu = NA,
|
col_icu = NA,
|
||||||
@ -118,11 +118,14 @@ first_isolate <- function(tbl,
|
|||||||
type = "keyantibiotics",
|
type = "keyantibiotics",
|
||||||
ignore_I = TRUE,
|
ignore_I = TRUE,
|
||||||
points_threshold = 2,
|
points_threshold = 2,
|
||||||
info = TRUE) {
|
info = TRUE,
|
||||||
|
col_genus = NA,
|
||||||
|
col_species = NA) {
|
||||||
|
|
||||||
# support tidyverse-like quotation
|
# support tidyverse-like quotation
|
||||||
col_date <- quasiquotate(deparse(substitute(col_date)), col_date)
|
col_date <- quasiquotate(deparse(substitute(col_date)), col_date)
|
||||||
col_patient_id <- quasiquotate(deparse(substitute(col_patient_id)), col_patient_id)
|
col_patient_id <- quasiquotate(deparse(substitute(col_patient_id)), col_patient_id)
|
||||||
|
col_bactid <- quasiquotate(deparse(substitute(col_bactid)), col_bactid)
|
||||||
col_genus <- quasiquotate(deparse(substitute(col_genus)), col_genus)
|
col_genus <- quasiquotate(deparse(substitute(col_genus)), col_genus)
|
||||||
col_species <- quasiquotate(deparse(substitute(col_species)), col_species)
|
col_species <- quasiquotate(deparse(substitute(col_species)), col_species)
|
||||||
col_testcode <- quasiquotate(deparse(substitute(col_testcode)), col_testcode)
|
col_testcode <- quasiquotate(deparse(substitute(col_testcode)), col_testcode)
|
||||||
@ -145,12 +148,19 @@ first_isolate <- function(tbl,
|
|||||||
|
|
||||||
check_columns_existance(col_date)
|
check_columns_existance(col_date)
|
||||||
check_columns_existance(col_patient_id)
|
check_columns_existance(col_patient_id)
|
||||||
|
check_columns_existance(col_bactid)
|
||||||
check_columns_existance(col_genus)
|
check_columns_existance(col_genus)
|
||||||
check_columns_existance(col_species)
|
check_columns_existance(col_species)
|
||||||
check_columns_existance(col_testcode)
|
check_columns_existance(col_testcode)
|
||||||
check_columns_existance(col_icu)
|
check_columns_existance(col_icu)
|
||||||
check_columns_existance(col_keyantibiotics)
|
check_columns_existance(col_keyantibiotics)
|
||||||
|
|
||||||
|
if (!is.na(col_bactid)) {
|
||||||
|
tbl <- tbl %>% left_join_microorganisms()
|
||||||
|
col_genus <- "genus"
|
||||||
|
col_species <- "species"
|
||||||
|
}
|
||||||
|
|
||||||
if (is.na(col_testcode)) {
|
if (is.na(col_testcode)) {
|
||||||
testcodes_exclude <- NA
|
testcodes_exclude <- NA
|
||||||
}
|
}
|
||||||
@ -395,7 +405,7 @@ first_isolate <- function(tbl,
|
|||||||
#' Key antibiotics based on bacteria ID
|
#' Key antibiotics based on bacteria ID
|
||||||
#'
|
#'
|
||||||
#' @param tbl table with antibiotics coloms, like \code{amox} and \code{amcl}.
|
#' @param tbl table with antibiotics coloms, like \code{amox} and \code{amcl}.
|
||||||
#' @param col_bactcode column of bacteria IDs in \code{tbl}; these should occur in \code{bactlist$bactid}, see \code{\link{bactlist}}
|
#' @param col_bactid column of bacteria IDs in \code{tbl}; these should occur in \code{microorganisms$bactid}, see \code{\link{microorganisms}}
|
||||||
#' @param info print warnings
|
#' @param info print warnings
|
||||||
#' @param amcl,amox,cfot,cfta,cftr,cfur,cipr,clar,clin,clox,doxy,gent,line,mero,peni,pita,rifa,teic,trsu,vanc column names of antibiotics, case-insensitive
|
#' @param amcl,amox,cfot,cfta,cftr,cfur,cipr,clar,clin,clox,doxy,gent,line,mero,peni,pita,rifa,teic,trsu,vanc column names of antibiotics, case-insensitive
|
||||||
#' @export
|
#' @export
|
||||||
@ -408,7 +418,7 @@ first_isolate <- function(tbl,
|
|||||||
#' tbl$keyab <- key_antibiotics(tbl)
|
#' tbl$keyab <- key_antibiotics(tbl)
|
||||||
#' }
|
#' }
|
||||||
key_antibiotics <- function(tbl,
|
key_antibiotics <- function(tbl,
|
||||||
col_bactcode = 'bactid',
|
col_bactid = 'bactid',
|
||||||
info = TRUE,
|
info = TRUE,
|
||||||
amcl = 'amcl',
|
amcl = 'amcl',
|
||||||
amox = 'amox',
|
amox = 'amox',
|
||||||
@ -443,6 +453,8 @@ key_antibiotics <- function(tbl,
|
|||||||
col.list[i] <- toupper(col.list[i])
|
col.list[i] <- toupper(col.list[i])
|
||||||
} else if (tolower(col.list[i]) %in% colnames(tbl)) {
|
} else if (tolower(col.list[i]) %in% colnames(tbl)) {
|
||||||
col.list[i] <- tolower(col.list[i])
|
col.list[i] <- tolower(col.list[i])
|
||||||
|
} else if (!col.list[i] %in% colnames(tbl)) {
|
||||||
|
col.list[i] <- NA
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
if (!all(col.list %in% colnames(tbl))) {
|
if (!all(col.list %in% colnames(tbl))) {
|
||||||
@ -473,8 +485,8 @@ key_antibiotics <- function(tbl,
|
|||||||
trsu <- col.list[18]
|
trsu <- col.list[18]
|
||||||
vanc <- col.list[19]
|
vanc <- col.list[19]
|
||||||
|
|
||||||
# join bactlist
|
# join microorganisms
|
||||||
tbl <- tbl %>% left_join_bactlist(col_bactcode)
|
tbl <- tbl %>% left_join_microorganisms(col_bactid)
|
||||||
|
|
||||||
tbl$key_ab <- NA_character_
|
tbl$key_ab <- NA_character_
|
||||||
|
|
||||||
@ -595,7 +607,7 @@ key_antibiotics_equal <- function(x,
|
|||||||
result[i] <- all(x2 == y2)
|
result[i] <- all(x2 == y2)
|
||||||
|
|
||||||
} else {
|
} else {
|
||||||
stop('`', type, '` is not a valid value for type, must be `points` or `keyantibiotics`. See ?first_isolate.')
|
stop('`', type, '` is not a valid value for type, must be "points" or "keyantibiotics". See ?first_isolate.')
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
@ -612,7 +624,7 @@ key_antibiotics_equal <- function(x,
|
|||||||
#' @export
|
#' @export
|
||||||
#' @importFrom dplyr %>% filter slice pull
|
#' @importFrom dplyr %>% filter slice pull
|
||||||
#' @return Character (vector).
|
#' @return Character (vector).
|
||||||
#' @seealso \code{\link{bactlist}} for the dataframe that is being used to determine ID's.
|
#' @seealso \code{\link{microorganisms}} for the dataframe that is being used to determine ID's.
|
||||||
#' @examples
|
#' @examples
|
||||||
#' # These examples all return "STAAUR", the ID of S. aureus:
|
#' # These examples all return "STAAUR", the ID of S. aureus:
|
||||||
#' guess_bactid("stau")
|
#' guess_bactid("stau")
|
||||||
@ -662,24 +674,24 @@ guess_bactid <- function(x) {
|
|||||||
}
|
}
|
||||||
|
|
||||||
# let's try the ID's first
|
# let's try the ID's first
|
||||||
found <- AMR::bactlist %>% filter(bactid == x.bak[i])
|
found <- AMR::microorganisms %>% filter(bactid == x.bak[i])
|
||||||
|
|
||||||
if (nrow(found) == 0) {
|
if (nrow(found) == 0) {
|
||||||
# now try exact match
|
# now try exact match
|
||||||
found <- AMR::bactlist %>% filter(fullname == x[i])
|
found <- AMR::microorganisms %>% filter(fullname == x[i])
|
||||||
}
|
}
|
||||||
if (nrow(found) == 0) {
|
if (nrow(found) == 0) {
|
||||||
# try any match
|
# try any match
|
||||||
found <- AMR::bactlist %>% filter(fullname %like% x[i])
|
found <- AMR::microorganisms %>% filter(fullname %like% x[i])
|
||||||
}
|
}
|
||||||
if (nrow(found) == 0) {
|
if (nrow(found) == 0) {
|
||||||
# try only genus, with 'species' attached
|
# try only genus, with 'species' attached
|
||||||
found <- AMR::bactlist %>% filter(fullname %like% x_species[i])
|
found <- AMR::microorganisms %>% filter(fullname %like% x_species[i])
|
||||||
}
|
}
|
||||||
if (nrow(found) == 0) {
|
if (nrow(found) == 0) {
|
||||||
# search for GLIMS code
|
# search for GLIMS code
|
||||||
if (toupper(x.bak[i]) %in% toupper(AMR::bactlist.umcg$mocode)) {
|
if (toupper(x.bak[i]) %in% toupper(AMR::microorganisms.umcg$mocode)) {
|
||||||
found <- AMR::bactlist.umcg %>% filter(toupper(mocode) == toupper(x.bak[i]))
|
found <- AMR::microorganisms.umcg %>% filter(toupper(mocode) == toupper(x.bak[i]))
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
if (nrow(found) == 0) {
|
if (nrow(found) == 0) {
|
||||||
@ -689,7 +701,7 @@ guess_bactid <- function(x) {
|
|||||||
x[i] <- paste0(x.bak[i] %>% substr(1, x_length / 2) %>% trimws(),
|
x[i] <- paste0(x.bak[i] %>% substr(1, x_length / 2) %>% trimws(),
|
||||||
'.* ',
|
'.* ',
|
||||||
x.bak[i] %>% substr((x_length / 2) + 1, x_length) %>% trimws())
|
x.bak[i] %>% substr((x_length / 2) + 1, x_length) %>% trimws())
|
||||||
found <- AMR::bactlist %>% filter(fullname %like% paste0('^', x[i]))
|
found <- AMR::microorganisms %>% filter(fullname %like% paste0('^', x[i]))
|
||||||
}
|
}
|
||||||
|
|
||||||
if (nrow(found) != 0) {
|
if (nrow(found) != 0) {
|
||||||
|
48
R/join.R
48
R/join.R
@ -1,20 +1,20 @@
|
|||||||
#' Join a table with \code{bactlist}
|
#' Join a table with \code{microorganisms}
|
||||||
#'
|
#'
|
||||||
#' Join the list of microorganisms \code{\link{bactlist}} easily to an existing table.
|
#' Join the dataset \code{\link{microorganisms}} easily to an existing table or character vector.
|
||||||
#' @rdname join
|
#' @rdname join
|
||||||
#' @name join
|
#' @name join
|
||||||
#' @aliases join inner_join
|
#' @aliases join inner_join
|
||||||
#' @param x existing table to join, also supports character vectors
|
#' @param x existing table to join, also supports character vectors
|
||||||
#' @param by a variable to join by - could be a column name of \code{x} with values that exist in \code{bactlist$bactid} (like \code{by = "bacteria_id"}), or another column in \code{\link{bactlist}} (but then it should be named, like \code{by = c("my_genus_species" = "fullname")})
|
#' @param by a variable to join by - could be a column name of \code{x} with values that exist in \code{microorganisms$bactid} (like \code{by = "bacteria_id"}), or another column in \code{\link{microorganisms}} (but then it should be named, like \code{by = c("my_genus_species" = "fullname")})
|
||||||
#' @param suffix if there are non-joined duplicate variables in \code{x} and \code{y}, these suffixes will be added to the output to disambiguate them. Should be a character vector of length 2.
|
#' @param suffix if there are non-joined duplicate variables in \code{x} and \code{y}, these suffixes will be added to the output to disambiguate them. Should be a character vector of length 2.
|
||||||
#' @param ... other parameters to pass on to \code{dplyr::\link[dplyr]{join}}.
|
#' @param ... other parameters to pass on to \code{dplyr::\link[dplyr]{join}}.
|
||||||
#' @details As opposed to the \code{\link[dplyr]{join}} functions of \code{dplyr}, characters vectors are supported and at default existing columns will get a suffix \code{"2"} and the newly joined columns will not get a suffix. See \code{\link[dplyr]{join}} for more information.
|
#' @details As opposed to the \code{\link[dplyr]{join}} functions of \code{dplyr}, characters vectors are supported and at default existing columns will get a suffix \code{"2"} and the newly joined columns will not get a suffix. See \code{\link[dplyr]{join}} for more information.
|
||||||
#' @export
|
#' @export
|
||||||
#' @examples
|
#' @examples
|
||||||
#' left_join_bactlist("STAAUR")
|
#' left_join_microorganisms("STAAUR")
|
||||||
#'
|
#'
|
||||||
#' library(dplyr)
|
#' library(dplyr)
|
||||||
#' septic_patients %>% left_join_bactlist()
|
#' septic_patients %>% left_join_microorganisms()
|
||||||
#'
|
#'
|
||||||
#' df <- data.frame(date = seq(from = as.Date("2018-01-01"),
|
#' df <- data.frame(date = seq(from = as.Date("2018-01-01"),
|
||||||
#' to = as.Date("2018-01-07"),
|
#' to = as.Date("2018-01-07"),
|
||||||
@ -23,20 +23,20 @@
|
|||||||
#' "ESCCOL", "ESCCOL", "ESCCOL"),
|
#' "ESCCOL", "ESCCOL", "ESCCOL"),
|
||||||
#' stringsAsFactors = FALSE)
|
#' stringsAsFactors = FALSE)
|
||||||
#' colnames(df)
|
#' colnames(df)
|
||||||
#' df2 <- left_join_bactlist(df, "bacteria_id")
|
#' df2 <- left_join_microorganisms(df, "bacteria_id")
|
||||||
#' colnames(df2)
|
#' colnames(df2)
|
||||||
inner_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
inner_join_microorganisms <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
||||||
if (any(class(x) %in% c('character', 'factor'))) {
|
if (any(class(x) %in% c('character', 'factor'))) {
|
||||||
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
||||||
}
|
}
|
||||||
# no name set to `by` parameter
|
# no name set to `by` parameter
|
||||||
if (is.null(names(by))) {
|
if (is.null(names(by))) {
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- by
|
names(joinby) <- by
|
||||||
} else {
|
} else {
|
||||||
joinby <- by
|
joinby <- by
|
||||||
}
|
}
|
||||||
join <- dplyr::inner_join(x = x, y = AMR::bactlist, by = joinby, suffix = c("2", ""), ...)
|
join <- dplyr::inner_join(x = x, y = AMR::microorganisms, by = joinby, suffix = c("2", ""), ...)
|
||||||
if (nrow(join) > nrow(x)) {
|
if (nrow(join) > nrow(x)) {
|
||||||
warning('the newly joined tbl contains ', nrow(join) - nrow(x), ' rows more that its original')
|
warning('the newly joined tbl contains ', nrow(join) - nrow(x), ' rows more that its original')
|
||||||
}
|
}
|
||||||
@ -45,18 +45,18 @@ inner_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
|||||||
|
|
||||||
#' @rdname join
|
#' @rdname join
|
||||||
#' @export
|
#' @export
|
||||||
left_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
left_join_microorganisms <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
||||||
if (any(class(x) %in% c('character', 'factor'))) {
|
if (any(class(x) %in% c('character', 'factor'))) {
|
||||||
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
||||||
}
|
}
|
||||||
# no name set to `by` parameter
|
# no name set to `by` parameter
|
||||||
if (is.null(names(by))) {
|
if (is.null(names(by))) {
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- by
|
names(joinby) <- by
|
||||||
} else {
|
} else {
|
||||||
joinby <- by
|
joinby <- by
|
||||||
}
|
}
|
||||||
join <- dplyr::left_join(x = x, y = AMR::bactlist, by = joinby, suffix = c("2", ""), ...)
|
join <- dplyr::left_join(x = x, y = AMR::microorganisms, by = joinby, suffix = c("2", ""), ...)
|
||||||
if (nrow(join) > nrow(x)) {
|
if (nrow(join) > nrow(x)) {
|
||||||
warning('the newly joined tbl contains ', nrow(join) - nrow(x), ' rows more that its original')
|
warning('the newly joined tbl contains ', nrow(join) - nrow(x), ' rows more that its original')
|
||||||
}
|
}
|
||||||
@ -65,18 +65,18 @@ left_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
|||||||
|
|
||||||
#' @rdname join
|
#' @rdname join
|
||||||
#' @export
|
#' @export
|
||||||
right_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
right_join_microorganisms <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
||||||
if (any(class(x) %in% c('character', 'factor'))) {
|
if (any(class(x) %in% c('character', 'factor'))) {
|
||||||
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
||||||
}
|
}
|
||||||
# no name set to `by` parameter
|
# no name set to `by` parameter
|
||||||
if (is.null(names(by))) {
|
if (is.null(names(by))) {
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- by
|
names(joinby) <- by
|
||||||
} else {
|
} else {
|
||||||
joinby <- by
|
joinby <- by
|
||||||
}
|
}
|
||||||
join <- dplyr::right_join(x = x, y = AMR::bactlist, by = joinby, suffix = c("2", ""), ...)
|
join <- dplyr::right_join(x = x, y = AMR::microorganisms, by = joinby, suffix = c("2", ""), ...)
|
||||||
if (nrow(join) > nrow(x)) {
|
if (nrow(join) > nrow(x)) {
|
||||||
warning('the newly joined tbl contains ', nrow(join) - nrow(x), ' rows more that its original')
|
warning('the newly joined tbl contains ', nrow(join) - nrow(x), ' rows more that its original')
|
||||||
}
|
}
|
||||||
@ -85,48 +85,48 @@ right_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
|||||||
|
|
||||||
#' @rdname join
|
#' @rdname join
|
||||||
#' @export
|
#' @export
|
||||||
full_join_bactlist <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
full_join_microorganisms <- function(x, by = 'bactid', suffix = c("2", ""), ...) {
|
||||||
if (any(class(x) %in% c('character', 'factor'))) {
|
if (any(class(x) %in% c('character', 'factor'))) {
|
||||||
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
||||||
}
|
}
|
||||||
# no name set to `by` parameter
|
# no name set to `by` parameter
|
||||||
if (is.null(names(by))) {
|
if (is.null(names(by))) {
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- by
|
names(joinby) <- by
|
||||||
} else {
|
} else {
|
||||||
joinby <- by
|
joinby <- by
|
||||||
}
|
}
|
||||||
dplyr::full_join(x = x, y = AMR::bactlist, by = joinby, suffix = c("2", ""), ...)
|
dplyr::full_join(x = x, y = AMR::microorganisms, by = joinby, suffix = c("2", ""), ...)
|
||||||
}
|
}
|
||||||
|
|
||||||
#' @rdname join
|
#' @rdname join
|
||||||
#' @export
|
#' @export
|
||||||
semi_join_bactlist <- function(x, by = 'bactid', ...) {
|
semi_join_microorganisms <- function(x, by = 'bactid', ...) {
|
||||||
if (any(class(x) %in% c('character', 'factor'))) {
|
if (any(class(x) %in% c('character', 'factor'))) {
|
||||||
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
||||||
}
|
}
|
||||||
# no name set to `by` parameter
|
# no name set to `by` parameter
|
||||||
if (is.null(names(by))) {
|
if (is.null(names(by))) {
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- by
|
names(joinby) <- by
|
||||||
} else {
|
} else {
|
||||||
joinby <- by
|
joinby <- by
|
||||||
}
|
}
|
||||||
dplyr::semi_join(x = x, y = AMR::bactlist, by = joinby, ...)
|
dplyr::semi_join(x = x, y = AMR::microorganisms, by = joinby, ...)
|
||||||
}
|
}
|
||||||
|
|
||||||
#' @rdname join
|
#' @rdname join
|
||||||
#' @export
|
#' @export
|
||||||
anti_join_bactlist <- function(x, by = 'bactid', ...) {
|
anti_join_microorganisms <- function(x, by = 'bactid', ...) {
|
||||||
if (any(class(x) %in% c('character', 'factor'))) {
|
if (any(class(x) %in% c('character', 'factor'))) {
|
||||||
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
x <- data.frame(bactid = x, stringsAsFactors = FALSE)
|
||||||
}
|
}
|
||||||
# no name set to `by` parameter
|
# no name set to `by` parameter
|
||||||
if (is.null(names(by))) {
|
if (is.null(names(by))) {
|
||||||
joinby <- colnames(AMR::bactlist)[1]
|
joinby <- colnames(AMR::microorganisms)[1]
|
||||||
names(joinby) <- by
|
names(joinby) <- by
|
||||||
} else {
|
} else {
|
||||||
joinby <- by
|
joinby <- by
|
||||||
}
|
}
|
||||||
dplyr::anti_join(x = x, y = AMR::bactlist, by = joinby, ...)
|
dplyr::anti_join(x = x, y = AMR::microorganisms, by = joinby, ...)
|
||||||
}
|
}
|
||||||
|
6
R/misc.R
6
R/misc.R
@ -40,9 +40,9 @@ quasiquotate <- function(deparsed, parsed) {
|
|||||||
}
|
}
|
||||||
# apply if needed
|
# apply if needed
|
||||||
if (any(!deparsed %like% '[[$:()]'
|
if (any(!deparsed %like% '[[$:()]'
|
||||||
& !deparsed %in% c('""', "''", "", # empty text
|
& !deparsed %in% c('""', "''", "", # empty text
|
||||||
".", ".data", # dplyr references
|
".", ".data", # dplyr references
|
||||||
"TRUE", "FALSE", # logicals
|
"TRUE", "FALSE", # logicals
|
||||||
"NA", "NaN", "NULL", # empty values
|
"NA", "NaN", "NULL", # empty values
|
||||||
ls(.GlobalEnv)))) {
|
ls(.GlobalEnv)))) {
|
||||||
deparsed
|
deparsed
|
||||||
|
124
R/rsi_analysis.R
124
R/rsi_analysis.R
@ -20,7 +20,7 @@
|
|||||||
#'
|
#'
|
||||||
#' \strong{NOTE: use \code{\link{rsi}} in dplyr functions like \code{\link[dplyr]{summarise}}.} \cr Calculate the percentage of S, SI, I, IR or R of a \code{data.frame} containing isolates.
|
#' \strong{NOTE: use \code{\link{rsi}} in dplyr functions like \code{\link[dplyr]{summarise}}.} \cr Calculate the percentage of S, SI, I, IR or R of a \code{data.frame} containing isolates.
|
||||||
#' @param tbl \code{data.frame} containing columns with antibiotic interpretations.
|
#' @param tbl \code{data.frame} containing columns with antibiotic interpretations.
|
||||||
#' @param antibiotics character vector with 1, 2 or 3 antibiotics that occur as column names in \code{tbl}, like \code{antibiotics = c("amox", "amcl")}
|
#' @param ab character vector with 1, 2 or 3 antibiotics that occur as column names in \code{tbl}, like \code{ab = c("amox", "amcl")}
|
||||||
#' @param interpretation antimicrobial interpretation of which the portion must be calculated. Valid values are \code{"S"}, \code{"SI"}, \code{"I"}, \code{"IR"} or \code{"R"}.
|
#' @param interpretation antimicrobial interpretation of which the portion must be calculated. Valid values are \code{"S"}, \code{"SI"}, \code{"I"}, \code{"IR"} or \code{"R"}.
|
||||||
#' @param minimum minimal amount of available isolates. Any number lower than \code{minimum} will return \code{NA} with a warning (when \code{warning = TRUE}).
|
#' @param minimum minimal amount of available isolates. Any number lower than \code{minimum} will return \code{NA} with a warning (when \code{warning = TRUE}).
|
||||||
#' @param percent return output as percent (text), will else (at default) be a double
|
#' @param percent return output as percent (text), will else (at default) be a double
|
||||||
@ -43,27 +43,27 @@
|
|||||||
#' my_table %>%
|
#' my_table %>%
|
||||||
#' filter(first_isolate == TRUE,
|
#' filter(first_isolate == TRUE,
|
||||||
#' genus == "Helicobacter") %>%
|
#' genus == "Helicobacter") %>%
|
||||||
#' rsi_df(antibiotics = c("amox", "metr"))
|
#' rsi_df(ab = c("amox", "metr"))
|
||||||
#' }
|
#' }
|
||||||
rsi_df <- function(tbl,
|
rsi_df <- function(tbl,
|
||||||
antibiotics,
|
ab,
|
||||||
interpretation = 'IR',
|
interpretation = 'IR',
|
||||||
minimum = 30,
|
minimum = 30,
|
||||||
percent = FALSE,
|
percent = FALSE,
|
||||||
info = TRUE,
|
info = TRUE,
|
||||||
warning = TRUE) {
|
warning = TRUE) {
|
||||||
|
|
||||||
|
# in case tbl$interpretation already exists:
|
||||||
|
interpretations_to_check <- paste(interpretation, collapse = "")
|
||||||
|
|
||||||
# we willen niet dat tbl$interpretation toevallig ook bestaat, dus:
|
# validate:
|
||||||
te_testen_uitslag_ab <- interpretation
|
if (min(grepl('^[a-z]{3,4}$', ab)) == 0 &
|
||||||
|
min(grepl('^rsi[1-2]$', ab)) == 0) {
|
||||||
# validatie:
|
for (i in 1:length(ab)) {
|
||||||
if (min(grepl('^[a-z]{3,4}$', antibiotics)) == 0 &
|
ab[i] <- paste0('rsi', i)
|
||||||
min(grepl('^rsi[1-2]$', antibiotics)) == 0) {
|
|
||||||
for (i in 1:length(antibiotics)) {
|
|
||||||
antibiotics[i] <- paste0('rsi', i)
|
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
if (!grepl('^(S|SI|IS|I|IR|RI|R){1}$', te_testen_uitslag_ab)) {
|
if (!grepl('^(S|SI|IS|I|IR|RI|R){1}$', interpretations_to_check)) {
|
||||||
stop('Invalid `interpretation`; must be "S", "SI", "I", "IR", or "R".')
|
stop('Invalid `interpretation`; must be "S", "SI", "I", "IR", or "R".')
|
||||||
}
|
}
|
||||||
if ('is_ic' %in% colnames(tbl)) {
|
if ('is_ic' %in% colnames(tbl)) {
|
||||||
@ -72,59 +72,59 @@ rsi_df <- function(tbl,
|
|||||||
}
|
}
|
||||||
}
|
}
|
||||||
|
|
||||||
# transformeren wanneer gezocht wordt op verschillende uitslagen
|
# transform when checking for different results
|
||||||
if (te_testen_uitslag_ab %in% c('SI', 'IS')) {
|
if (interpretations_to_check %in% c('SI', 'IS')) {
|
||||||
for (i in 1:length(antibiotics)) {
|
for (i in 1:length(ab)) {
|
||||||
lijst <- tbl[, antibiotics[i]]
|
lijst <- tbl[, ab[i]]
|
||||||
if ('I' %in% lijst) {
|
if ('I' %in% lijst) {
|
||||||
tbl[which(tbl[antibiotics[i]] == 'I'), ][antibiotics[i]] <- 'S'
|
tbl[which(tbl[ab[i]] == 'I'), ][ab[i]] <- 'S'
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
te_testen_uitslag_ab <- 'S'
|
interpretations_to_check <- 'S'
|
||||||
}
|
}
|
||||||
if (te_testen_uitslag_ab %in% c('RI', 'IR')) {
|
if (interpretations_to_check %in% c('RI', 'IR')) {
|
||||||
for (i in 1:length(antibiotics)) {
|
for (i in 1:length(ab)) {
|
||||||
lijst <- tbl[, antibiotics[i]]
|
lijst <- tbl[, ab[i]]
|
||||||
if ('I' %in% lijst) {
|
if ('I' %in% lijst) {
|
||||||
tbl[which(tbl[antibiotics[i]] == 'I'), ][antibiotics[i]] <- 'R'
|
tbl[which(tbl[ab[i]] == 'I'), ][ab[i]] <- 'R'
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
te_testen_uitslag_ab <- 'R'
|
interpretations_to_check <- 'R'
|
||||||
}
|
}
|
||||||
|
|
||||||
# breuk samenstellen
|
# get fraction
|
||||||
if (length(antibiotics) == 1) {
|
if (length(ab) == 1) {
|
||||||
numerator <- tbl %>%
|
numerator <- tbl %>%
|
||||||
filter(pull(., antibiotics[1]) == te_testen_uitslag_ab) %>%
|
filter(pull(., ab[1]) == interpretations_to_check) %>%
|
||||||
nrow()
|
nrow()
|
||||||
|
|
||||||
denominator <- tbl %>%
|
denominator <- tbl %>%
|
||||||
filter(pull(., antibiotics[1]) %in% c("S", "I", "R")) %>%
|
filter(pull(., ab[1]) %in% c("S", "I", "R")) %>%
|
||||||
nrow()
|
nrow()
|
||||||
|
|
||||||
} else if (length(antibiotics) == 2) {
|
} else if (length(ab) == 2) {
|
||||||
numerator <- tbl %>%
|
numerator <- tbl %>%
|
||||||
filter_at(vars(antibiotics[1], antibiotics[2]),
|
filter_at(vars(ab[1], ab[2]),
|
||||||
any_vars(. == te_testen_uitslag_ab)) %>%
|
any_vars(. == interpretations_to_check)) %>%
|
||||||
filter_at(vars(antibiotics[1], antibiotics[2]),
|
filter_at(vars(ab[1], ab[2]),
|
||||||
all_vars(. %in% c("S", "R", "I"))) %>%
|
all_vars(. %in% c("S", "R", "I"))) %>%
|
||||||
nrow()
|
nrow()
|
||||||
|
|
||||||
denominator <- tbl %>%
|
denominator <- tbl %>%
|
||||||
filter_at(vars(antibiotics[1], antibiotics[2]),
|
filter_at(vars(ab[1], ab[2]),
|
||||||
all_vars(. %in% c("S", "R", "I"))) %>%
|
all_vars(. %in% c("S", "R", "I"))) %>%
|
||||||
nrow()
|
nrow()
|
||||||
|
|
||||||
} else if (length(antibiotics) == 3) {
|
} else if (length(ab) == 3) {
|
||||||
numerator <- tbl %>%
|
numerator <- tbl %>%
|
||||||
filter_at(vars(antibiotics[1], antibiotics[2], antibiotics[3]),
|
filter_at(vars(ab[1], ab[2], ab[3]),
|
||||||
any_vars(. == te_testen_uitslag_ab)) %>%
|
any_vars(. == interpretations_to_check)) %>%
|
||||||
filter_at(vars(antibiotics[1], antibiotics[2], antibiotics[3]),
|
filter_at(vars(ab[1], ab[2], ab[3]),
|
||||||
all_vars(. %in% c("S", "R", "I"))) %>%
|
all_vars(. %in% c("S", "R", "I"))) %>%
|
||||||
nrow()
|
nrow()
|
||||||
|
|
||||||
denominator <- tbl %>%
|
denominator <- tbl %>%
|
||||||
filter_at(vars(antibiotics[1], antibiotics[2], antibiotics[3]),
|
filter_at(vars(ab[1], ab[2], ab[3]),
|
||||||
all_vars(. %in% c("S", "R", "I"))) %>%
|
all_vars(. %in% c("S", "R", "I"))) %>%
|
||||||
nrow()
|
nrow()
|
||||||
|
|
||||||
@ -132,7 +132,7 @@ rsi_df <- function(tbl,
|
|||||||
stop('Maximum of 3 drugs allowed.')
|
stop('Maximum of 3 drugs allowed.')
|
||||||
}
|
}
|
||||||
|
|
||||||
# tekstdeel opbouwen
|
# build text part
|
||||||
if (info == TRUE) {
|
if (info == TRUE) {
|
||||||
cat('n =', denominator)
|
cat('n =', denominator)
|
||||||
info.txt1 <- percent(denominator / nrow(tbl))
|
info.txt1 <- percent(denominator / nrow(tbl))
|
||||||
@ -140,23 +140,22 @@ rsi_df <- function(tbl,
|
|||||||
info.txt1 <- 'none'
|
info.txt1 <- 'none'
|
||||||
}
|
}
|
||||||
info.txt2 <- gsub(',', ' and',
|
info.txt2 <- gsub(',', ' and',
|
||||||
antibiotics %>%
|
ab %>%
|
||||||
abname(to = 'trivial',
|
abname(tolower = TRUE) %>%
|
||||||
tolower = TRUE) %>%
|
|
||||||
toString(), fixed = TRUE)
|
toString(), fixed = TRUE)
|
||||||
info.txt2 <- gsub('rsi1 and rsi2', 'these two drugs', info.txt2, fixed = TRUE)
|
info.txt2 <- gsub('rsi1 and rsi2', 'these two drugs', info.txt2, fixed = TRUE)
|
||||||
info.txt2 <- gsub('rsi1', 'this drug', info.txt2, fixed = TRUE)
|
info.txt2 <- gsub('rsi1', 'this drug', info.txt2, fixed = TRUE)
|
||||||
cat(paste0(' (of ', nrow(tbl), ' in total; ', info.txt1, ' tested on ', info.txt2, ')\n'))
|
cat(paste0(' (of ', nrow(tbl), ' in total; ', info.txt1, ' tested on ', info.txt2, ')\n'))
|
||||||
}
|
}
|
||||||
|
|
||||||
# rekenen en opmaken
|
# calculate and format
|
||||||
y <- numerator / denominator
|
y <- numerator / denominator
|
||||||
if (percent == TRUE) {
|
if (percent == TRUE) {
|
||||||
y <- percent(y)
|
y <- percent(y)
|
||||||
}
|
}
|
||||||
if (denominator < minimum) {
|
if (denominator < minimum) {
|
||||||
if (warning == TRUE) {
|
if (warning == TRUE) {
|
||||||
warning(paste0('TOO FEW ISOLATES OF ', toString(antibiotics), ' (n = ', denominator, ', n < ', minimum, '); NO RESULT.'))
|
warning(paste0('TOO FEW ISOLATES OF ', toString(ab), ' (n = ', denominator, ', n < ', minimum, '); NO RESULT.'))
|
||||||
}
|
}
|
||||||
y <- NA
|
y <- NA
|
||||||
}
|
}
|
||||||
@ -192,26 +191,31 @@ rsi_df <- function(tbl,
|
|||||||
#' rsi(as.rsi(isolates$amcl), interpretation = "S")
|
#' rsi(as.rsi(isolates$amcl), interpretation = "S")
|
||||||
#' }
|
#' }
|
||||||
rsi <- function(ab1, ab2 = NA, interpretation = 'IR', minimum = 30, percent = FALSE, info = FALSE, warning = FALSE) {
|
rsi <- function(ab1, ab2 = NA, interpretation = 'IR', minimum = 30, percent = FALSE, info = FALSE, warning = FALSE) {
|
||||||
function_text <- as.character(match.call())
|
ab1.name <- deparse(substitute(ab1))
|
||||||
# param 1 = functienaam
|
if (ab1.name %like% '.[$].') {
|
||||||
# param 2 = ab1
|
ab1.name <- unlist(strsplit(ab1.name, "$", fixed = TRUE))
|
||||||
# param 3 = ab2
|
ab1.name <- ab1.name[length(ab1.name)]
|
||||||
ab1.naam <- function_text[2]
|
|
||||||
if (!grepl('^[a-z]{3,4}$', ab1.naam)) {
|
|
||||||
ab1.naam <- 'rsi1'
|
|
||||||
}
|
}
|
||||||
ab2.naam <- function_text[3]
|
if (!ab1.name %like% '^[a-z]{3,4}$') {
|
||||||
if (!grepl('^[a-z]{3,4}$', ab2.naam)) {
|
ab1.name <- 'rsi1'
|
||||||
ab2.naam <- 'rsi2'
|
|
||||||
}
|
}
|
||||||
|
ab2.name <- deparse(substitute(ab2))
|
||||||
|
if (ab2.name %like% '.[$].') {
|
||||||
|
ab2.name <- unlist(strsplit(ab2.name, "$", fixed = TRUE))
|
||||||
|
ab2.name <- ab2.name[length(ab2.name)]
|
||||||
|
}
|
||||||
|
if (!ab2.name %like% '^[a-z]{3,4}$') {
|
||||||
|
ab2.name <- 'rsi2'
|
||||||
|
}
|
||||||
|
|
||||||
|
interpretation <- paste(interpretation, collapse = "")
|
||||||
|
|
||||||
tbl <- tibble(rsi1 = ab1, rsi2 = ab2)
|
tbl <- tibble(rsi1 = ab1, rsi2 = ab2)
|
||||||
|
colnames(tbl) <- c(ab1.name, ab2.name)
|
||||||
colnames(tbl) <- c(ab1.naam, ab2.naam)
|
|
||||||
|
|
||||||
if (length(ab2) == 1) {
|
if (length(ab2) == 1) {
|
||||||
return(rsi_df(tbl = tbl,
|
return(rsi_df(tbl = tbl,
|
||||||
antibiotics = ab1.naam,
|
ab = ab1.name,
|
||||||
interpretation = interpretation,
|
interpretation = interpretation,
|
||||||
minimum = minimum,
|
minimum = minimum,
|
||||||
percent = percent,
|
percent = percent,
|
||||||
@ -225,7 +229,7 @@ rsi <- function(ab1, ab2 = NA, interpretation = 'IR', minimum = 30, percent = FA
|
|||||||
warning('`interpretation` is not set to S, albeit analysing a combination therapy.')
|
warning('`interpretation` is not set to S, albeit analysing a combination therapy.')
|
||||||
}
|
}
|
||||||
return(rsi_df(tbl = tbl,
|
return(rsi_df(tbl = tbl,
|
||||||
antibiotics = c(ab1.naam, ab2.naam),
|
ab = c(ab1.name, ab2.name),
|
||||||
interpretation = interpretation,
|
interpretation = interpretation,
|
||||||
minimum = minimum,
|
minimum = minimum,
|
||||||
percent = percent,
|
percent = percent,
|
||||||
@ -270,7 +274,7 @@ rsi <- function(ab1, ab2 = NA, interpretation = 'IR', minimum = 30, percent = FA
|
|||||||
#' library(dplyr)
|
#' library(dplyr)
|
||||||
#' septic_patients %>%
|
#' septic_patients %>%
|
||||||
#' # get bacteria properties like genus and species
|
#' # get bacteria properties like genus and species
|
||||||
#' left_join_bactlist("bactid") %>%
|
#' left_join_microorganisms("bactid") %>%
|
||||||
#' # calculate first isolates
|
#' # calculate first isolates
|
||||||
#' mutate(first_isolate =
|
#' mutate(first_isolate =
|
||||||
#' first_isolate(.,
|
#' first_isolate(.,
|
||||||
|
Binary file not shown.
Binary file not shown.
BIN
data/microorganisms.rda
Normal file
BIN
data/microorganisms.rda
Normal file
Binary file not shown.
BIN
data/microorganisms.umcg.rda
Normal file
BIN
data/microorganisms.umcg.rda
Normal file
Binary file not shown.
@ -9,11 +9,11 @@ EUCAST Expert Rules Version 2.0: \cr
|
|||||||
Leclercq et al. \strong{EUCAST expert rules in antimicrobial susceptibility testing.} \emph{Clin Microbiol Infect.} 2013;19(2):141-60. \cr
|
Leclercq et al. \strong{EUCAST expert rules in antimicrobial susceptibility testing.} \emph{Clin Microbiol Infect.} 2013;19(2):141-60. \cr
|
||||||
\url{https://doi.org/10.1111/j.1469-0691.2011.03703.x} \cr
|
\url{https://doi.org/10.1111/j.1469-0691.2011.03703.x} \cr
|
||||||
\cr
|
\cr
|
||||||
EUCAST Expert Rules Version 3.1: \cr
|
EUCAST Expert Rules Version 3.1 (Intrinsic Resistance and Exceptional Phenotypes Tables): \cr
|
||||||
\url{http://www.eucast.org/expert_rules_and_intrinsic_resistance}
|
\url{http://www.eucast.org/fileadmin/src/media/PDFs/EUCAST_files/Expert_Rules/Expert_rules_intrinsic_exceptional_V3.1.pdf}
|
||||||
}
|
}
|
||||||
\usage{
|
\usage{
|
||||||
EUCAST_rules(tbl, col_bactcode = "bactid", info = TRUE, amcl = "amcl",
|
EUCAST_rules(tbl, col_bactid = "bactid", info = TRUE, amcl = "amcl",
|
||||||
amik = "amik", amox = "amox", ampi = "ampi", azit = "azit",
|
amik = "amik", amox = "amox", ampi = "ampi", azit = "azit",
|
||||||
aztr = "aztr", cefa = "cefa", cfra = "cfra", cfep = "cfep",
|
aztr = "aztr", cefa = "cefa", cfra = "cfra", cfep = "cfep",
|
||||||
cfot = "cfot", cfox = "cfox", cfta = "cfta", cftr = "cftr",
|
cfot = "cfot", cfox = "cfox", cfta = "cfta", cftr = "cftr",
|
||||||
@ -35,7 +35,7 @@ interpretive_reading(...)
|
|||||||
\arguments{
|
\arguments{
|
||||||
\item{tbl}{table with antibiotic columns, like e.g. \code{amox} and \code{amcl}}
|
\item{tbl}{table with antibiotic columns, like e.g. \code{amox} and \code{amcl}}
|
||||||
|
|
||||||
\item{col_bactcode}{column name of the bacteria ID in \code{tbl} - values of this column should be present in \code{bactlist$bactid}, see \code{\link{bactlist}}}
|
\item{col_bactid}{column name of the bacteria ID in \code{tbl} - values of this column should be present in \code{microorganisms$bactid}, see \code{\link{microorganisms}}}
|
||||||
|
|
||||||
\item{info}{print progress}
|
\item{info}{print progress}
|
||||||
|
|
||||||
|
@ -7,13 +7,13 @@
|
|||||||
\code{\link{antibiotics}}
|
\code{\link{antibiotics}}
|
||||||
}
|
}
|
||||||
\usage{
|
\usage{
|
||||||
abname(abcode, from = "umcg", to = "official", textbetween = " + ",
|
abname(abcode, from = c("guess", "atc", "molis", "umcg"), to = "official",
|
||||||
tolower = FALSE)
|
textbetween = " + ", tolower = FALSE)
|
||||||
}
|
}
|
||||||
\arguments{
|
\arguments{
|
||||||
\item{abcode}{a code or name, like \code{"AMOX"}, \code{"AMCL"} or \code{"J01CA04"}}
|
\item{abcode}{a code or name, like \code{"AMOX"}, \code{"AMCL"} or \code{"J01CA04"}}
|
||||||
|
|
||||||
\item{from, to}{type to transform from and to. See \code{\link{antibiotics}} for its column names.}
|
\item{from, to}{type to transform from and to. See \code{\link{antibiotics}} for its column names. WIth \code{from = "guess"} the from will be guessed from \code{"atc"}, \code{"molis"} and \code{"umcg"}.}
|
||||||
|
|
||||||
\item{textbetween}{text to put between multiple returned texts}
|
\item{textbetween}{text to put between multiple returned texts}
|
||||||
|
|
||||||
|
@ -33,6 +33,6 @@ antibiotics
|
|||||||
A dataset containing all antibiotics with a J0 code, with their DDD's. Properties were downloaded from the WHO, see Source.
|
A dataset containing all antibiotics with a J0 code, with their DDD's. Properties were downloaded from the WHO, see Source.
|
||||||
}
|
}
|
||||||
\seealso{
|
\seealso{
|
||||||
\code{\link{bactlist}}
|
\code{\link{microorganisms}}
|
||||||
}
|
}
|
||||||
\keyword{datasets}
|
\keyword{datasets}
|
||||||
|
50
man/clipboard.Rd
Normal file
50
man/clipboard.Rd
Normal file
@ -0,0 +1,50 @@
|
|||||||
|
% Generated by roxygen2: do not edit by hand
|
||||||
|
% Please edit documentation in R/clipboard.R
|
||||||
|
\name{clipboard}
|
||||||
|
\alias{clipboard}
|
||||||
|
\alias{clipboard_import}
|
||||||
|
\alias{clipboard_export}
|
||||||
|
\title{Import/export from clipboard}
|
||||||
|
\usage{
|
||||||
|
clipboard_import(sep = "\\t", header = TRUE, dec = ".", na = c("", "NA",
|
||||||
|
"NULL"), startrow = 1, as_vector = TRUE)
|
||||||
|
|
||||||
|
clipboard_export(x, sep = "\\t", dec = ".", na = "", header = TRUE)
|
||||||
|
}
|
||||||
|
\arguments{
|
||||||
|
\item{sep}{the field separator character. Values on each line of the
|
||||||
|
file are separated by this character. If \code{sep = ""} (the
|
||||||
|
default for \code{read.table}) the separator is \sQuote{white space},
|
||||||
|
that is one or more spaces, tabs, newlines or carriage returns.}
|
||||||
|
|
||||||
|
\item{header}{a logical value indicating whether the file contains the
|
||||||
|
names of the variables as its first line. If missing, the value is
|
||||||
|
determined from the file format: \code{header} is set to \code{TRUE}
|
||||||
|
if and only if the first row contains one fewer field than the
|
||||||
|
number of columns.}
|
||||||
|
|
||||||
|
\item{dec}{the character used in the file for decimal points.}
|
||||||
|
|
||||||
|
\item{na}{the string to use for missing values in the data.}
|
||||||
|
|
||||||
|
\item{startrow}{\emph{n}th row to start importing from. For \code{clipboard_import}, when \code{header = TRUE} the import will start on row \code{startrow} \emph{below} the header.}
|
||||||
|
|
||||||
|
\item{as_vector}{a logical value indicating whether data consisting of only one column should be imported as vector using \code{\link[dplyr]{pull}}. This will strip off the header.}
|
||||||
|
|
||||||
|
\item{x}{the object to be written, preferably a matrix or data frame.
|
||||||
|
If not, it is attempted to coerce \code{x} to a data frame.}
|
||||||
|
}
|
||||||
|
\value{
|
||||||
|
data.frame
|
||||||
|
}
|
||||||
|
\description{
|
||||||
|
These are helper functions around \code{\link{read.table}} and \code{\link{write.table}} to import from and export to clipboard. The data will be read and written as tab-separated by default, which makes it possible to copy and paste from other software like Excel and SPSS without further transformation.
|
||||||
|
}
|
||||||
|
\details{
|
||||||
|
For \code{clipboard_export}, the reserved clipboard size for exporting will be set automatically to 125\% of the object size of \code{x}. This way, it is possible to export data with thousands of rows as the only limit will be your systems RAM.
|
||||||
|
}
|
||||||
|
\keyword{clipboard}
|
||||||
|
\keyword{clipboard_export}
|
||||||
|
\keyword{clipboard_import}
|
||||||
|
\keyword{export}
|
||||||
|
\keyword{import}
|
@ -4,12 +4,12 @@
|
|||||||
\alias{first_isolate}
|
\alias{first_isolate}
|
||||||
\title{Determine first (weighted) isolates}
|
\title{Determine first (weighted) isolates}
|
||||||
\usage{
|
\usage{
|
||||||
first_isolate(tbl, col_date, col_patient_id, col_genus, col_species,
|
first_isolate(tbl, col_date, col_patient_id, col_bactid = NA,
|
||||||
col_testcode = NA, col_specimen = NA, col_icu = NA,
|
col_testcode = NA, col_specimen = NA, col_icu = NA,
|
||||||
col_keyantibiotics = NA, episode_days = 365, testcodes_exclude = "",
|
col_keyantibiotics = NA, episode_days = 365, testcodes_exclude = "",
|
||||||
icu_exclude = FALSE, filter_specimen = NA, output_logical = TRUE,
|
icu_exclude = FALSE, filter_specimen = NA, output_logical = TRUE,
|
||||||
type = "keyantibiotics", ignore_I = TRUE, points_threshold = 2,
|
type = "keyantibiotics", ignore_I = TRUE, points_threshold = 2,
|
||||||
info = TRUE)
|
info = TRUE, col_genus = NA, col_species = NA)
|
||||||
}
|
}
|
||||||
\arguments{
|
\arguments{
|
||||||
\item{tbl}{a \code{data.frame} containing isolates.}
|
\item{tbl}{a \code{data.frame} containing isolates.}
|
||||||
@ -18,9 +18,7 @@ first_isolate(tbl, col_date, col_patient_id, col_genus, col_species,
|
|||||||
|
|
||||||
\item{col_patient_id}{column name of the unique IDs of the patients, supports tidyverse-like quotation}
|
\item{col_patient_id}{column name of the unique IDs of the patients, supports tidyverse-like quotation}
|
||||||
|
|
||||||
\item{col_genus}{column name of the genus of the microorganisms, supports tidyverse-like quotation}
|
\item{col_bactid}{column name of the unique IDs of the microorganisms (should occur in the \code{\link{microorganisms}} dataset), supports tidyverse-like quotation}
|
||||||
|
|
||||||
\item{col_species}{column name of the species of the microorganisms, supports tidyverse-like quotation}
|
|
||||||
|
|
||||||
\item{col_testcode}{column name of the test codes. Use \code{col_testcode = NA} to \strong{not} exclude certain test codes (like test codes for screening). In that case \code{testcodes_exclude} will be ignored. Supports tidyverse-like quotation.}
|
\item{col_testcode}{column name of the test codes. Use \code{col_testcode = NA} to \strong{not} exclude certain test codes (like test codes for screening). In that case \code{testcodes_exclude} will be ignored. Supports tidyverse-like quotation.}
|
||||||
|
|
||||||
@ -47,6 +45,10 @@ first_isolate(tbl, col_date, col_patient_id, col_genus, col_species,
|
|||||||
\item{points_threshold}{points until the comparison of key antibiotics will lead to inclusion of an isolate when \code{type = "points"}, see Details}
|
\item{points_threshold}{points until the comparison of key antibiotics will lead to inclusion of an isolate when \code{type = "points"}, see Details}
|
||||||
|
|
||||||
\item{info}{print progress}
|
\item{info}{print progress}
|
||||||
|
|
||||||
|
\item{col_genus}{(deprecated, use \code{col_bactid} instead) column name of the genus of the microorganisms, supports tidyverse-like quotation}
|
||||||
|
|
||||||
|
\item{col_species}{(deprecated, use \code{col_bactid} instead) column name of the species of the microorganisms, supports tidyverse-like quotation}
|
||||||
}
|
}
|
||||||
\value{
|
\value{
|
||||||
A vector to add to table, see Examples.
|
A vector to add to table, see Examples.
|
||||||
@ -71,7 +73,7 @@ my_patients <- septic_patients
|
|||||||
|
|
||||||
library(dplyr)
|
library(dplyr)
|
||||||
my_patients$first_isolate <- my_patients \%>\%
|
my_patients$first_isolate <- my_patients \%>\%
|
||||||
left_join_bactlist() \%>\%
|
left_join_microorganisms() \%>\%
|
||||||
first_isolate(col_date = date,
|
first_isolate(col_date = date,
|
||||||
col_patient_id = patient_id,
|
col_patient_id = patient_id,
|
||||||
col_genus = genus,
|
col_genus = genus,
|
||||||
|
@ -27,5 +27,5 @@ guess_bactid("MRSA") # Methicillin-resistant S. aureus
|
|||||||
guess_bactid("VISA") # Vancomycin Intermediate S. aureus
|
guess_bactid("VISA") # Vancomycin Intermediate S. aureus
|
||||||
}
|
}
|
||||||
\seealso{
|
\seealso{
|
||||||
\code{\link{bactlist}} for the dataframe that is being used to determine ID's.
|
\code{\link{microorganisms}} for the dataframe that is being used to determine ID's.
|
||||||
}
|
}
|
||||||
|
36
man/join.Rd
36
man/join.Rd
@ -2,47 +2,47 @@
|
|||||||
% Please edit documentation in R/join.R
|
% Please edit documentation in R/join.R
|
||||||
\name{join}
|
\name{join}
|
||||||
\alias{join}
|
\alias{join}
|
||||||
\alias{inner_join_bactlist}
|
\alias{inner_join_microorganisms}
|
||||||
\alias{inner_join}
|
\alias{inner_join}
|
||||||
\alias{left_join_bactlist}
|
\alias{left_join_microorganisms}
|
||||||
\alias{right_join_bactlist}
|
\alias{right_join_microorganisms}
|
||||||
\alias{full_join_bactlist}
|
\alias{full_join_microorganisms}
|
||||||
\alias{semi_join_bactlist}
|
\alias{semi_join_microorganisms}
|
||||||
\alias{anti_join_bactlist}
|
\alias{anti_join_microorganisms}
|
||||||
\title{Join a table with \code{bactlist}}
|
\title{Join a table with \code{microorganisms}}
|
||||||
\usage{
|
\usage{
|
||||||
inner_join_bactlist(x, by = "bactid", suffix = c("2", ""), ...)
|
inner_join_microorganisms(x, by = "bactid", suffix = c("2", ""), ...)
|
||||||
|
|
||||||
left_join_bactlist(x, by = "bactid", suffix = c("2", ""), ...)
|
left_join_microorganisms(x, by = "bactid", suffix = c("2", ""), ...)
|
||||||
|
|
||||||
right_join_bactlist(x, by = "bactid", suffix = c("2", ""), ...)
|
right_join_microorganisms(x, by = "bactid", suffix = c("2", ""), ...)
|
||||||
|
|
||||||
full_join_bactlist(x, by = "bactid", suffix = c("2", ""), ...)
|
full_join_microorganisms(x, by = "bactid", suffix = c("2", ""), ...)
|
||||||
|
|
||||||
semi_join_bactlist(x, by = "bactid", ...)
|
semi_join_microorganisms(x, by = "bactid", ...)
|
||||||
|
|
||||||
anti_join_bactlist(x, by = "bactid", ...)
|
anti_join_microorganisms(x, by = "bactid", ...)
|
||||||
}
|
}
|
||||||
\arguments{
|
\arguments{
|
||||||
\item{x}{existing table to join, also supports character vectors}
|
\item{x}{existing table to join, also supports character vectors}
|
||||||
|
|
||||||
\item{by}{a variable to join by - could be a column name of \code{x} with values that exist in \code{bactlist$bactid} (like \code{by = "bacteria_id"}), or another column in \code{\link{bactlist}} (but then it should be named, like \code{by = c("my_genus_species" = "fullname")})}
|
\item{by}{a variable to join by - could be a column name of \code{x} with values that exist in \code{microorganisms$bactid} (like \code{by = "bacteria_id"}), or another column in \code{\link{microorganisms}} (but then it should be named, like \code{by = c("my_genus_species" = "fullname")})}
|
||||||
|
|
||||||
\item{suffix}{if there are non-joined duplicate variables in \code{x} and \code{y}, these suffixes will be added to the output to disambiguate them. Should be a character vector of length 2.}
|
\item{suffix}{if there are non-joined duplicate variables in \code{x} and \code{y}, these suffixes will be added to the output to disambiguate them. Should be a character vector of length 2.}
|
||||||
|
|
||||||
\item{...}{other parameters to pass on to \code{dplyr::\link[dplyr]{join}}.}
|
\item{...}{other parameters to pass on to \code{dplyr::\link[dplyr]{join}}.}
|
||||||
}
|
}
|
||||||
\description{
|
\description{
|
||||||
Join the list of microorganisms \code{\link{bactlist}} easily to an existing table.
|
Join the dataset \code{\link{microorganisms}} easily to an existing table or character vector.
|
||||||
}
|
}
|
||||||
\details{
|
\details{
|
||||||
As opposed to the \code{\link[dplyr]{join}} functions of \code{dplyr}, characters vectors are supported and at default existing columns will get a suffix \code{"2"} and the newly joined columns will not get a suffix. See \code{\link[dplyr]{join}} for more information.
|
As opposed to the \code{\link[dplyr]{join}} functions of \code{dplyr}, characters vectors are supported and at default existing columns will get a suffix \code{"2"} and the newly joined columns will not get a suffix. See \code{\link[dplyr]{join}} for more information.
|
||||||
}
|
}
|
||||||
\examples{
|
\examples{
|
||||||
left_join_bactlist("STAAUR")
|
left_join_microorganisms("STAAUR")
|
||||||
|
|
||||||
library(dplyr)
|
library(dplyr)
|
||||||
septic_patients \%>\% left_join_bactlist()
|
septic_patients \%>\% left_join_microorganisms()
|
||||||
|
|
||||||
df <- data.frame(date = seq(from = as.Date("2018-01-01"),
|
df <- data.frame(date = seq(from = as.Date("2018-01-01"),
|
||||||
to = as.Date("2018-01-07"),
|
to = as.Date("2018-01-07"),
|
||||||
@ -51,6 +51,6 @@ df <- data.frame(date = seq(from = as.Date("2018-01-01"),
|
|||||||
"ESCCOL", "ESCCOL", "ESCCOL"),
|
"ESCCOL", "ESCCOL", "ESCCOL"),
|
||||||
stringsAsFactors = FALSE)
|
stringsAsFactors = FALSE)
|
||||||
colnames(df)
|
colnames(df)
|
||||||
df2 <- left_join_bactlist(df, "bacteria_id")
|
df2 <- left_join_microorganisms(df, "bacteria_id")
|
||||||
colnames(df2)
|
colnames(df2)
|
||||||
}
|
}
|
||||||
|
@ -4,7 +4,7 @@
|
|||||||
\alias{key_antibiotics}
|
\alias{key_antibiotics}
|
||||||
\title{Key antibiotics based on bacteria ID}
|
\title{Key antibiotics based on bacteria ID}
|
||||||
\usage{
|
\usage{
|
||||||
key_antibiotics(tbl, col_bactcode = "bactid", info = TRUE, amcl = "amcl",
|
key_antibiotics(tbl, col_bactid = "bactid", info = TRUE, amcl = "amcl",
|
||||||
amox = "amox", cfot = "cfot", cfta = "cfta", cftr = "cftr",
|
amox = "amox", cfot = "cfot", cfta = "cfta", cftr = "cftr",
|
||||||
cfur = "cfur", cipr = "cipr", clar = "clar", clin = "clin",
|
cfur = "cfur", cipr = "cipr", clar = "clar", clin = "clin",
|
||||||
clox = "clox", doxy = "doxy", gent = "gent", line = "line",
|
clox = "clox", doxy = "doxy", gent = "gent", line = "line",
|
||||||
@ -14,7 +14,7 @@ key_antibiotics(tbl, col_bactcode = "bactid", info = TRUE, amcl = "amcl",
|
|||||||
\arguments{
|
\arguments{
|
||||||
\item{tbl}{table with antibiotics coloms, like \code{amox} and \code{amcl}.}
|
\item{tbl}{table with antibiotics coloms, like \code{amox} and \code{amcl}.}
|
||||||
|
|
||||||
\item{col_bactcode}{column of bacteria IDs in \code{tbl}; these should occur in \code{bactlist$bactid}, see \code{\link{bactlist}}}
|
\item{col_bactid}{column of bacteria IDs in \code{tbl}; these should occur in \code{microorganisms$bactid}, see \code{\link{microorganisms}}}
|
||||||
|
|
||||||
\item{info}{print warnings}
|
\item{info}{print warnings}
|
||||||
|
|
||||||
|
@ -1,8 +1,8 @@
|
|||||||
% Generated by roxygen2: do not edit by hand
|
% Generated by roxygen2: do not edit by hand
|
||||||
% Please edit documentation in R/data.R
|
% Please edit documentation in R/data.R
|
||||||
\docType{data}
|
\docType{data}
|
||||||
\name{bactlist}
|
\name{microorganisms}
|
||||||
\alias{bactlist}
|
\alias{microorganisms}
|
||||||
\title{Dataset with ~2500 microorganisms}
|
\title{Dataset with ~2500 microorganisms}
|
||||||
\format{A data.frame with 2507 observations and 12 variables:
|
\format{A data.frame with 2507 observations and 12 variables:
|
||||||
\describe{
|
\describe{
|
||||||
@ -23,12 +23,12 @@
|
|||||||
MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
||||||
}
|
}
|
||||||
\usage{
|
\usage{
|
||||||
bactlist
|
microorganisms
|
||||||
}
|
}
|
||||||
\description{
|
\description{
|
||||||
A dataset containing all microorganisms of MOLIS. MO codes of the UMCG can be looked up using \code{\link{bactlist.umcg}}.
|
A dataset containing 2500 microorganisms. MO codes of the UMCG can be looked up using \code{\link{microorganisms.umcg}}.
|
||||||
}
|
}
|
||||||
\seealso{
|
\seealso{
|
||||||
\code{\link{guess_bactid}} \code{\link{antibiotics}} \code{\link{bactlist.umcg}}
|
\code{\link{guess_bactid}} \code{\link{antibiotics}} \code{\link{microorganisms.umcg}}
|
||||||
}
|
}
|
||||||
\keyword{datasets}
|
\keyword{datasets}
|
@ -1,24 +1,24 @@
|
|||||||
% Generated by roxygen2: do not edit by hand
|
% Generated by roxygen2: do not edit by hand
|
||||||
% Please edit documentation in R/data.R
|
% Please edit documentation in R/data.R
|
||||||
\docType{data}
|
\docType{data}
|
||||||
\name{bactlist.umcg}
|
\name{microorganisms.umcg}
|
||||||
\alias{bactlist.umcg}
|
\alias{microorganisms.umcg}
|
||||||
\title{Translation table for UMCG with ~1100 microorganisms}
|
\title{Translation table for UMCG with ~1100 microorganisms}
|
||||||
\format{A data.frame with 1090 observations and 2 variables:
|
\format{A data.frame with 1090 observations and 2 variables:
|
||||||
\describe{
|
\describe{
|
||||||
\item{\code{mocode}}{Code of microorganism according to UMCG MMB}
|
\item{\code{mocode}}{Code of microorganism according to UMCG MMB}
|
||||||
\item{\code{bactid}}{Code of microorganism in \code{\link{bactlist}}}
|
\item{\code{bactid}}{Code of microorganism in \code{\link{microorganisms}}}
|
||||||
}}
|
}}
|
||||||
\source{
|
\source{
|
||||||
MOLIS (LIS of Certe) - \url{https://www.certe.nl} \cr \cr GLIMS (LIS of UMCG) - \url{https://www.umcg.nl}
|
MOLIS (LIS of Certe) - \url{https://www.certe.nl} \cr \cr GLIMS (LIS of UMCG) - \url{https://www.umcg.nl}
|
||||||
}
|
}
|
||||||
\usage{
|
\usage{
|
||||||
bactlist.umcg
|
microorganisms.umcg
|
||||||
}
|
}
|
||||||
\description{
|
\description{
|
||||||
A dataset containing all bacteria codes of UMCG MMB. These codes can be joined to data with an ID from \code{\link{bactlist}$bactid} (using \code{\link{left_join_bactlist}}). GLIMS codes can also be translated to valid \code{bactid}'s with \code{\link{guess_bactid}}.
|
A dataset containing all bacteria codes of UMCG MMB. These codes can be joined to data with an ID from \code{\link{microorganisms}$bactid} (using \code{\link{left_join_microorganisms}}). GLIMS codes can also be translated to valid \code{bactid}'s with \code{\link{guess_bactid}}.
|
||||||
}
|
}
|
||||||
\seealso{
|
\seealso{
|
||||||
\code{\link{guess_bactid}} \code{\link{bactlist}}
|
\code{\link{guess_bactid}} \code{\link{microorganisms}}
|
||||||
}
|
}
|
||||||
\keyword{datasets}
|
\keyword{datasets}
|
@ -4,10 +4,10 @@
|
|||||||
\alias{mo_property}
|
\alias{mo_property}
|
||||||
\title{Poperties of a microorganism}
|
\title{Poperties of a microorganism}
|
||||||
\usage{
|
\usage{
|
||||||
mo_property(bactcode, property = "fullname")
|
mo_property(bactid, property = "fullname")
|
||||||
}
|
}
|
||||||
\arguments{
|
\arguments{
|
||||||
\item{bactcode}{ID of a microorganisme, like \code{"STAAUR} and \code{"ESCCOL}}
|
\item{bactid}{ID of a microorganisme, like \code{"STAAUR} and \code{"ESCCOL}}
|
||||||
|
|
||||||
\item{property}{One of the values \code{bactid}, \code{bactsys}, \code{family}, \code{genus}, \code{species}, \code{subspecies}, \code{fullname}, \code{type}, \code{gramstain}, \code{aerobic}}
|
\item{property}{One of the values \code{bactid}, \code{bactsys}, \code{family}, \code{genus}, \code{species}, \code{subspecies}, \code{fullname}, \code{type}, \code{gramstain}, \code{aerobic}}
|
||||||
}
|
}
|
||||||
@ -15,5 +15,5 @@ mo_property(bactcode, property = "fullname")
|
|||||||
Poperties of a microorganism
|
Poperties of a microorganism
|
||||||
}
|
}
|
||||||
\seealso{
|
\seealso{
|
||||||
\code{\link{bactlist}}
|
\code{\link{microorganisms}}
|
||||||
}
|
}
|
||||||
|
@ -4,13 +4,13 @@
|
|||||||
\alias{rsi_df}
|
\alias{rsi_df}
|
||||||
\title{Resistance of isolates in data.frame}
|
\title{Resistance of isolates in data.frame}
|
||||||
\usage{
|
\usage{
|
||||||
rsi_df(tbl, antibiotics, interpretation = "IR", minimum = 30,
|
rsi_df(tbl, ab, interpretation = "IR", minimum = 30, percent = FALSE,
|
||||||
percent = FALSE, info = TRUE, warning = TRUE)
|
info = TRUE, warning = TRUE)
|
||||||
}
|
}
|
||||||
\arguments{
|
\arguments{
|
||||||
\item{tbl}{\code{data.frame} containing columns with antibiotic interpretations.}
|
\item{tbl}{\code{data.frame} containing columns with antibiotic interpretations.}
|
||||||
|
|
||||||
\item{antibiotics}{character vector with 1, 2 or 3 antibiotics that occur as column names in \code{tbl}, like \code{antibiotics = c("amox", "amcl")}}
|
\item{ab}{character vector with 1, 2 or 3 antibiotics that occur as column names in \code{tbl}, like \code{ab = c("amox", "amcl")}}
|
||||||
|
|
||||||
\item{interpretation}{antimicrobial interpretation of which the portion must be calculated. Valid values are \code{"S"}, \code{"SI"}, \code{"I"}, \code{"IR"} or \code{"R"}.}
|
\item{interpretation}{antimicrobial interpretation of which the portion must be calculated. Valid values are \code{"S"}, \code{"SI"}, \code{"I"}, \code{"IR"} or \code{"R"}.}
|
||||||
|
|
||||||
@ -42,7 +42,7 @@ library(dplyr)
|
|||||||
my_table \%>\%
|
my_table \%>\%
|
||||||
filter(first_isolate == TRUE,
|
filter(first_isolate == TRUE,
|
||||||
genus == "Helicobacter") \%>\%
|
genus == "Helicobacter") \%>\%
|
||||||
rsi_df(antibiotics = c("amox", "metr"))
|
rsi_df(ab = c("amox", "metr"))
|
||||||
}
|
}
|
||||||
}
|
}
|
||||||
\seealso{
|
\seealso{
|
||||||
|
@ -53,7 +53,7 @@ tbl \%>\%
|
|||||||
library(dplyr)
|
library(dplyr)
|
||||||
septic_patients \%>\%
|
septic_patients \%>\%
|
||||||
# get bacteria properties like genus and species
|
# get bacteria properties like genus and species
|
||||||
left_join_bactlist("bactid") \%>\%
|
left_join_microorganisms("bactid") \%>\%
|
||||||
# calculate first isolates
|
# calculate first isolates
|
||||||
mutate(first_isolate =
|
mutate(first_isolate =
|
||||||
first_isolate(.,
|
first_isolate(.,
|
||||||
|
@ -14,8 +14,8 @@
|
|||||||
\item{\code{age}}{age of the patient}
|
\item{\code{age}}{age of the patient}
|
||||||
\item{\code{sex}}{sex of the patient}
|
\item{\code{sex}}{sex of the patient}
|
||||||
\item{\code{patient_id}}{ID of the patient, first 10 characters of an SHA hash containing irretrievable information}
|
\item{\code{patient_id}}{ID of the patient, first 10 characters of an SHA hash containing irretrievable information}
|
||||||
\item{\code{bactid}}{ID of microorganism, see \code{\link{bactlist}}}
|
\item{\code{bactid}}{ID of microorganism, see \code{\link{microorganisms}}}
|
||||||
\item{\code{peni:mupi}}{38 different antibiotics with class \code{rsi} (see \code{\link{as.rsi}}), these column names occur in \code{\link{antibiotics}} and can be translated with \code{\link{abname}}}
|
\item{\code{peni:mupi}}{38 different antibiotics with class \code{rsi} (see \code{\link{as.rsi}}); these column names occur in \code{\link{antibiotics}} and can be translated with \code{\link{abname}}}
|
||||||
}}
|
}}
|
||||||
\source{
|
\source{
|
||||||
MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
||||||
@ -24,6 +24,46 @@ MOLIS (LIS of Certe) - \url{https://www.certe.nl}
|
|||||||
septic_patients
|
septic_patients
|
||||||
}
|
}
|
||||||
\description{
|
\description{
|
||||||
An anonymised dataset containing 2000 microbial blood culture isolates with their antibiogram of septic patients found in 5 different hospitals in the Netherlands, between 2001 and 2017. This data.frame can be used to practice AMR analysis e.g. with \code{\link{rsi}} or \code{\link{rsi_predict}}, or it can be used to practice other statistics.
|
An anonymised dataset containing 2000 microbial blood culture isolates with their antibiogram of septic patients found in 5 different hospitals in the Netherlands, between 2001 and 2017. This data.frame can be used to practice AMR analysis. For examples, press F1.
|
||||||
|
}
|
||||||
|
\examples{
|
||||||
|
# ----------- #
|
||||||
|
# PREPARATION #
|
||||||
|
# ----------- #
|
||||||
|
|
||||||
|
# Save this example dataset to an object, so we can edit it:
|
||||||
|
my_data <- septic_patients
|
||||||
|
|
||||||
|
# load the dplyr package to make data science A LOT easier
|
||||||
|
library(dplyr)
|
||||||
|
|
||||||
|
# Add first isolates to our dataset:
|
||||||
|
my_data <- my_data \%>\%
|
||||||
|
mutate(first_isolates = first_isolate(my_data, date, patient_id, bactid))
|
||||||
|
|
||||||
|
# -------- #
|
||||||
|
# ANALYSIS #
|
||||||
|
# -------- #
|
||||||
|
|
||||||
|
# 1. Get the amoxicillin resistance percentages
|
||||||
|
# of E. coli, divided by hospital:
|
||||||
|
|
||||||
|
my_data \%>\%
|
||||||
|
filter(bactid == "ESCCOL",
|
||||||
|
first_isolates == TRUE) \%>\%
|
||||||
|
group_by(hospital_id) \%>\%
|
||||||
|
summarise(n = n(),
|
||||||
|
amoxicillin_resistance = rsi(amox))
|
||||||
|
|
||||||
|
|
||||||
|
# 2. Get the amoxicillin/clavulanic acid resistance
|
||||||
|
# percentages of E. coli, trend over the years:
|
||||||
|
|
||||||
|
my_data \%>\%
|
||||||
|
filter(bactid == guess_bactid("E. coli"),
|
||||||
|
first_isolates == TRUE) \%>\%
|
||||||
|
group_by(year = format(date, "\%Y")) \%>\%
|
||||||
|
summarise(n = n(),
|
||||||
|
amoxclav_resistance = rsi(amcl, minimum = 20))
|
||||||
}
|
}
|
||||||
\keyword{datasets}
|
\keyword{datasets}
|
||||||
|
Loading…
Reference in New Issue
Block a user