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mirror of https://github.com/msberends/AMR.git synced 2025-07-08 20:02:04 +02:00

(v1.7.1.9054) mdro() update - fixes #49, first_isolate() speedup

This commit is contained in:
2021-11-28 23:01:26 +01:00
parent 9a2c431e16
commit 694cf5ba77
72 changed files with 780 additions and 669 deletions

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9f708801889d2eaf974c6eb85c83a8e7
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@ -214,7 +214,7 @@
"GAT" 5379 "Gatifloxacin" "Quinolones" "c(\"J01MA16\", \"S01AE06\")" "Quinolone antibacterials" "Fluoroquinolones" "c(\"\", \"gati\")" "c(\"gatiflo\", \"gatifloxacin\", \"gatifloxacine\", \"gatifloxcin\", \"gatilox\", \"gatiquin\", \"gatispan\", \"tequin\", \"tequin and zymar\", \"zymaxid\")" 0.4 "g" 0.4 "g" "character(0)"
"GEM" 9571107 "Gemifloxacin" "Quinolones" "J01MA15" "Quinolone antibacterials" "Fluoroquinolones" "" "c(\"factiv\", \"factive\", \"gemifioxacin\", \"gemifloxacin\", \"gemifloxacine\", \"gemifloxacino\", \"gemifloxacinum\")" 0.32 "g" "character(0)"
"GEN" 3467 "Gentamicin" "Aminoglycosides" "c(\"D06AX07\", \"J01GB03\", \"S01AA11\", \"S02AA14\", \"S03AA06\")" "Aminoglycoside antibacterials" "Other aminoglycosides" "c(\"cn\", \"gen\", \"gent\", \"gm\")" "c(\"apogen\", \"centicin\", \"cidomycin\", \"garasol\", \"genoptic liquifilm\", \"genoptic s.o.p.\", \"gentacycol\", \"gentafair\", \"gentak\", \"gentamar\", \"gentamcin sulfate\", \"gentamicin\", \"gentamicina\", \"gentamicine\", \"gentamicins\", \"gentamicinum\", \"gentamycin\", \"gentamycins\", \"gentamycinum\", \"gentavet\", \"gentocin\", \"jenamicin\", \"lyramycin\", \"oksitselanim\", \"refobacin\", \"refobacin tm\", \"septigen\", \"uromycine\")" 0.24 "g" "c(\"13561-6\", \"13562-4\", \"15106-8\", \"22746-2\", \"22747-0\", \"31091-2\", \"31092-0\", \"31093-8\", \"35668-3\", \"3663-2\", \"3664-0\", \"3665-7\", \"39082-3\", \"47109-4\", \"59379-8\", \"80971-5\", \"88111-0\")"
"GEH" "Gentamicin-high" "Aminoglycosides" "c(\"g_h\", \"gehl\", \"genta high\", \"gentamicin high\")" "" ""
"GEH" "Gentamicin-high" "Aminoglycosides" "c(\"gehi\", \"gehl\", \"genta high\", \"gentamicin high\")" "" ""
"GEP" 25101874 "Gepotidacin" "Other antibacterials" "" "gepotidacin" "character(0)"
"GRX" 72474 "Grepafloxacin" "Quinolones" "J01MA11" "Quinolone antibacterials" "Fluoroquinolones" "c(\"\", \"grep\")" "grepafloxacin" 0.4 "g" "character(0)"
"GRI" 441140 "Griseofulvin" "Antifungals/antimycotics" "c(\"D01AA08\", \"D01BA01\")" "" "c(\"amudane\", \"curling factor\", \"delmofulvina\", \"fulcin\", \"fulcine\", \"fulvican grisactin\", \"fulvicin\", \"fulvicin bolus\", \"fulvidex\", \"fulvina\", \"fulvinil\", \"fulvistatin\", \"fungivin\", \"greosin\", \"gresfeed\", \"gricin\", \"grifulin\", \"grifulvin\", \"grifulvin v\", \"grisactin\", \"grisactin ultra\", \"grisactin v\", \"griscofulvin\", \"grise ostatin\", \"grisefuline\", \"griseo\", \"griseofulvin\", \"griseofulvin forte\", \"griseofulvina\", \"griseofulvine\", \"griseofulvinum\", \"griseomix\", \"griseostatin\", \"grisetin\", \"grisofulvin\",
@ -403,7 +403,7 @@
"SPM" "Spiramycin/metronidazole" "Other antibacterials" "J01RA04" "Combinations of antibacterials" "Combinations of antibacterials" "" "" ""
"STR" "Streptoduocin" "Aminoglycosides" "J01GA02" "Aminoglycoside antibacterials" "Streptomycins" "" "" 1 "g" ""
"STR1" 19649 "Streptomycin" "Aminoglycosides" "c(\"A07AA04\", \"J01GA01\")" "Aminoglycoside antibacterials" "Streptomycins" "c(\"s\", \"stm\", \"str\", \"stre\")" "c(\"agrept\", \"agrimycin\", \"chemform\", \"estreptomicina\", \"neodiestreptopab\", \"strepcen\", \"streptomicina\", \"streptomycin\", \"streptomycin a\", \"streptomycin spx\", \"streptomycin sulfate\", \"streptomycine\", \"streptomyzin\", \"vetstrep\")" 1 "g" "4039-4"
"STH" "Streptomycin-high" "Aminoglycosides" "c(\"s_h\", \"sthl\", \"strepto high\", \"streptomycin high\")" "" ""
"STH" "Streptomycin-high" "Aminoglycosides" "c(\"sthi\", \"sthl\", \"strepto high\", \"streptomycin high\")" "" ""
"STI" "Streptomycin/isoniazid" "Antimycobacterials" "J04AM01" "Drugs for treatment of tuberculosis" "Combinations of drugs for treatment of tuberculosis" "" "" ""
"SUL" 130313 "Sulbactam" "Beta-lactams/penicillins" "J01CG01" "Beta-lactam antibacterials, penicillins" "Beta-lactamase inhibitors" "" "c(\"betamaze\", \"sulbactam\", \"sulbactam acid\", \"sulbactam free acid\", \"sulbactamum\")" 1 "g" "character(0)"
"SBC" 20055036 "Sulbenicillin" "Beta-lactams/penicillins" "J01CA16" "Beta-lactam antibacterials, penicillins" "Penicillins with extended spectrum" "" "c(\"kedacillina\", \"sulbenicilina\", \"sulbenicilline\", \"sulbenicillinum\")" 15 "g" "character(0)"

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ex2 <- example_isolates
for (extra_id in seq_len(50)) {
ex2 <- ex2 %>%
bind_rows(example_isolates %>% mutate(patient_id = paste0(patient_id, extra_id)))
}
# randomly clear antibibiograms of 2%
clr <- sort(sample(x = seq_len(nrow(ex2)),
size = nrow(ex2) * 0.02))
for (row in which(is.rsi(ex2))) {
ex2[clr, row] <- NA_rsi_
}

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@ -546,8 +546,8 @@ antibiotics[which(antibiotics$ab == "FEP"), "abbreviations"][[1]] <- list(c(anti
antibiotics[which(antibiotics$ab == "CTC"), "abbreviations"][[1]] <- list(c("xctl"))
antibiotics[which(antibiotics$ab == "CTX"), "abbreviations"][[1]] <- list(c(antibiotics[which(antibiotics$ab == "CTX"), "abbreviations"][[1]], "xct"))
# High level Gentamcin and Streptomycin
antibiotics[which(antibiotics$ab == "GEH"), "abbreviations"][[1]] <- list(c("gehl", "gentamicin high", "genta high"))
antibiotics[which(antibiotics$ab == "STH"), "abbreviations"][[1]] <- list(c("sthl", "streptomycin high", "strepto high"))
antibiotics[which(antibiotics$ab == "GEH"), "abbreviations"][[1]] <- list(c("gehl", "gentamicin high", "genta high", "gehi"))
antibiotics[which(antibiotics$ab == "STH"), "abbreviations"][[1]] <- list(c("sthl", "streptomycin high", "strepto high", "sthi"))
# add imi and "imipenem/cilastatine" to imipenem
antibiotics[which(antibiotics$ab == "IPM"), "abbreviations"][[1]] <- list(c("imip", "imi", "imp"))
antibiotics[which(antibiotics$ab == "IPM"), "synonyms"][[1]] <- list(sort(c(antibiotics[which(antibiotics$ab == "IPM"), "synonyms"][[1]], "imipenem/cilastatin")))