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<a class="navbar-brand me-2" href="https://msberends.github.io/AMR/index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -31,7 +31,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -92,7 +92,7 @@
website update since they are based on randomly created values and the
page was written in <a href="https://rmarkdown.rstudio.com/" class="external-link">R
Markdown</a>. However, the methodology remains unchanged. This page was
generated on 31 March 2025.</p>
generated on 07 April 2025.</p>
<div class="section level2">
<h2 id="introduction">Introduction<a class="anchor" aria-label="anchor" href="#introduction"></a>
</h2>
@ -148,21 +148,21 @@ make the structure of your data generally look like this:</p>
</tr></thead>
<tbody>
<tr class="odd">
<td align="center">2025-03-31</td>
<td align="center">2025-04-07</td>
<td align="center">abcd</td>
<td align="center">Escherichia coli</td>
<td align="center">S</td>
<td align="center">S</td>
</tr>
<tr class="even">
<td align="center">2025-03-31</td>
<td align="center">2025-04-07</td>
<td align="center">abcd</td>
<td align="center">Escherichia coli</td>
<td align="center">S</td>
<td align="center">R</td>
</tr>
<tr class="odd">
<td align="center">2025-03-31</td>
<td align="center">2025-04-07</td>
<td align="center">efgh</td>
<td align="center">Escherichia coli</td>
<td align="center">R</td>
@ -472,15 +472,15 @@ impression, as it comes with support for the new <code>mo</code> and
<span><span class="fu"><a href="https://pillar.r-lib.org/reference/glimpse.html" class="external-link">glimpse</a></span><span class="op">(</span><span class="va">our_data_1st</span><span class="op">)</span></span>
<span><span class="co">#&gt; Rows: 2,724</span></span>
<span><span class="co">#&gt; Columns: 9</span></span>
<span><span class="co">#&gt; $ patient_id <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "J3", "R7", "P3", "P10", "B7", "W3", "M3", "J3", "G6", "P4"…</span></span>
<span><span class="co">#&gt; $ hospital <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "A", "A", "A", "A", "A", "A", "A", "A", "A", "A", "A", "A",…</span></span>
<span><span class="co">#&gt; $ date <span style="color: #949494; font-style: italic;">&lt;date&gt;</span> 2012-11-21, 2018-04-03, 2014-09-19, 2015-12-10, 2015-03-02…</span></span>
<span><span class="co">#&gt; $ bacteria <span style="color: #949494; font-style: italic;">&lt;mo&gt;</span> "B_ESCHR_COLI", "B_KLBSL_PNMN", "B_ESCHR_COLI", "B_ESCHR_COL…</span></span>
<span><span class="co">#&gt; $ AMX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, R, S, S, R, R, S, S, S, S, R, S, S, R, R, R, R, S, R,…</span></span>
<span><span class="co">#&gt; $ AMC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> I, I, S, I, S, S, S, S, S, S, S, S, S, S, S, S, S, R, S, S,…</span></span>
<span><span class="co">#&gt; $ CIP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> S, S, S, S, S, R, S, S, S, S, S, S, S, S, S, S, S, S, S, S,…</span></span>
<span><span class="co">#&gt; $ GEN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> S, S, S, S, S, S, S, S, S, S, S, R, S, S, S, S, S, S, S, S,…</span></span>
<span><span class="co">#&gt; $ first <span style="color: #949494; font-style: italic;">&lt;lgl&gt;</span> TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE,…</span></span>
<span><span class="co">#&gt; $ patient_id <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "J3"<span style="color: #949494;">, </span>"R7"<span style="color: #949494;">, </span>"P3"<span style="color: #949494;">, </span>"P10"<span style="color: #949494;">, </span>"B7"<span style="color: #949494;">, </span>"W3"<span style="color: #949494;">, </span>"M3"<span style="color: #949494;">, </span>"J3"<span style="color: #949494;">, </span>"G6"<span style="color: #949494;">, </span>"P4"…</span></span>
<span><span class="co">#&gt; $ hospital <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">, </span>"A"<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ date <span style="color: #949494; font-style: italic;">&lt;date&gt;</span> 2012-11-21<span style="color: #949494;">, </span>2018-04-03<span style="color: #949494;">, </span>2014-09-19<span style="color: #949494;">, </span>2015-12-10<span style="color: #949494;">, </span>2015-03-02…</span></span>
<span><span class="co">#&gt; $ bacteria <span style="color: #949494; font-style: italic;">&lt;mo&gt;</span> "B_ESCHR_COLI"<span style="color: #949494;">, </span>"B_KLBSL_PNMN"<span style="color: #949494;">, </span>"B_ESCHR_COLI"<span style="color: #949494;">, </span>"B_ESCHR_COL…</span></span>
<span><span class="co">#&gt; $ AMX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ AMC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> I<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ CIP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ GEN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ first <span style="color: #949494; font-style: italic;">&lt;lgl&gt;</span> TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">, </span>TRUE<span style="color: #949494;">,</span>…</span></span>
<span></span>
<span><span class="co"># number of unique values per column:</span></span>
<span><span class="fu"><a href="https://rdrr.io/r/base/lapply.html" class="external-link">sapply</a></span><span class="op">(</span><span class="va">our_data_1st</span>, <span class="va">n_distinct</span><span class="op">)</span></span>
@ -1147,9 +1147,9 @@ incidence and antimicrobial susceptibility patterns.</p>
<th align="left">Piperacillin/tazobactam + Tobramycin</th>
</tr></thead>
<tbody><tr class="odd">
<td align="left">71.7% (57.5-83.6%)</td>
<td align="left">95.1% (88.9-98.6%)</td>
<td align="left">91.1% (81.4-96.9%)</td>
<td align="left">69.2% (51-85.2%)</td>
<td align="left">92.9% (84-98.5%)</td>
<td align="left">89% (76.4-96.9%)</td>
</tr></tbody>
</table>
<p>WISCA uses a <strong>Bayesian decision model</strong> to integrate
@ -1190,56 +1190,56 @@ function on a grouped <code>tibble</code>, i.e., using
<tr class="odd">
<td align="left">0-24</td>
<td align="left">F</td>
<td align="left">66.8% (13.5-98.9%)</td>
<td align="left">57.5% (7-98.4%)</td>
<td align="left">74.6% (30.6-98.9%)</td>
<td align="left">77.9% (34.5-99.1%)</td>
<td align="left">69.7% (24.5-98.5%)</td>
</tr>
<tr class="even">
<td align="left">0-24</td>
<td align="left">M</td>
<td align="left">75.4% (34-99.1%)</td>
<td align="left">59% (14.8-97.9%)</td>
<td align="left">80% (40.6-99.2%)</td>
<td align="left">76.1% (33.7-99.2%)</td>
<td align="left">60.1% (15-98.2%)</td>
</tr>
<tr class="odd">
<td align="left">25-49</td>
<td align="left">F</td>
<td align="left">88.5% (67.7-98.9%)</td>
<td align="left">65.4% (30.2-97.9%)</td>
<td align="left">91.6% (72.9-99.7%)</td>
<td align="left">82.6% (49.7-99.3%)</td>
</tr>
<tr class="even">
<td align="left">25-49</td>
<td align="left">M</td>
<td align="left">74.7% (38.4-97.5%)</td>
<td align="left">54.4% (10.9-97.3%)</td>
<td align="left">89.4% (66.7-99.7%)</td>
<td align="left">76.3% (33.1-99.1%)</td>
<td align="left">70.7% (26.9-98.6%)</td>
</tr>
<tr class="odd">
<td align="left">50-74</td>
<td align="left">F</td>
<td align="left">75.4% (61-90.6%)</td>
<td align="left">68.2% (44.6-92.6%)</td>
<td align="left">95.8% (87.6-99.5%)</td>
<td align="left">88.3% (71-97.7%)</td>
</tr>
<tr class="even">
<td align="left">50-74</td>
<td align="left">M</td>
<td align="left">66.9% (46.2-85.6%)</td>
<td align="left">65.8% (43.7-86.2%)</td>
<td align="left">95.3% (86-99.6%)</td>
<td align="left">83.7% (62.9-97%)</td>
</tr>
<tr class="odd">
<td align="left">75+</td>
<td align="left">F</td>
<td align="left">73.3% (51.3-91.6%)</td>
<td align="left">71.8% (48-92%)</td>
<td align="left">96.6% (90-99.7%)</td>
<td align="left">90.8% (76.5-98.8%)</td>
</tr>
<tr class="even">
<td align="left">75+</td>
<td align="left">M</td>
<td align="left">73.9% (55.7-89.4%)</td>
<td align="left">72.9% (53.7-89.7%)</td>
<td align="left">96.7% (89.9-99.7%)</td>
<td align="left">92.5% (80.3-98.9%)</td>
</tr>

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@ -31,7 +31,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -31,7 +31,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -31,7 +31,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -31,7 +31,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -31,7 +31,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -105,52 +105,52 @@ is currently being developed.</strong></p>
<span><span class="fu"><a href="https://pillar.r-lib.org/reference/glimpse.html" class="external-link">glimpse</a></span><span class="op">(</span><span class="va">example_isolates</span><span class="op">)</span></span>
<span><span class="co">#&gt; Rows: 2,000</span></span>
<span><span class="co">#&gt; Columns: 46</span></span>
<span><span class="co">#&gt; $ date <span style="color: #949494; font-style: italic;">&lt;date&gt;</span> 2002-01-02, 2002-01-03, 2002-01-07, 2002-01-07, 2002-01-13, 2…</span></span>
<span><span class="co">#&gt; $ patient <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "A77334", "A77334", "067927", "067927", "067927", "067927", "4…</span></span>
<span><span class="co">#&gt; $ age <span style="color: #949494; font-style: italic;">&lt;dbl&gt;</span> 65, 65, 45, 45, 45, 45, 78, 78, 45, 79, 67, 67, 71, 71, 75, 50…</span></span>
<span><span class="co">#&gt; $ gender <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "F", "F", "F", "F", "F", "F", "M", "M", "F", "F", "M", "M", "M…</span></span>
<span><span class="co">#&gt; $ ward <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "Clinical", "Clinical", "ICU", "ICU", "ICU", "ICU", "Clinical"…</span></span>
<span><span class="co">#&gt; $ mo <span style="color: #949494; font-style: italic;">&lt;mo&gt;</span> "B_ESCHR_COLI", "B_ESCHR_COLI", "B_STPHY_EPDR", "B_STPHY_EPDR",…</span></span>
<span><span class="co">#&gt; $ PEN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, R, S,…</span></span>
<span><span class="co">#&gt; $ OXA <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ FLC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, S, S, R, S, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R…</span></span>
<span><span class="co">#&gt; $ AMX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ AMC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> I, I, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, I, I, R, I, I, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ AMP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ TZP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ CZO <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, <span style="color: #BB0000;">NA</span>,…</span></span>
<span><span class="co">#&gt; $ FEP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ CXM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> I, I, R, R, R, R, S, S, R, S, S, S, S, S, <span style="color: #BB0000;">NA</span>, S, S, R, R, S, S…</span></span>
<span><span class="co">#&gt; $ FOX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, <span style="color: #BB0000;">NA</span>,…</span></span>
<span><span class="co">#&gt; $ CTX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, S, S…</span></span>
<span><span class="co">#&gt; $ CAZ <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, R, R, R, R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, R, R, …</span></span>
<span><span class="co">#&gt; $ CRO <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, S, S…</span></span>
<span><span class="co">#&gt; $ GEN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ TOB <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ AMK <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ KAN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ TMP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, S, S, R, R, R, R, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, S, S, S, R, R, R, …</span></span>
<span><span class="co">#&gt; $ SXT <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, S, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ NIT <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R,…</span></span>
<span><span class="co">#&gt; $ FOS <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ LNZ <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, <span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ CIP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S…</span></span>
<span><span class="co">#&gt; $ MFX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ VAN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, S, S, S, S, S, S, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, S, S, S, …</span></span>
<span><span class="co">#&gt; $ TEC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, <span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ TCY <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, S, S, S, S, S, S, S, I, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, I, R, R, S, I, R, …</span></span>
<span><span class="co">#&gt; $ TGC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, S, S, S, S, S, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, S, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ DOX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, S, S, S, S, S, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, S, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ ERY <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, R, R, R, R, S, S, R, S, S, S, R, R, R, R, R, R, R, R, S,…</span></span>
<span><span class="co">#&gt; $ CLI <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ AZM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, R, R, R, R, S, S, R, S, S, S, R, R, R, R, R, R, R, R, S,…</span></span>
<span><span class="co">#&gt; $ IPM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, S, S, <span style="color: #BB0000;">NA</span>, S, S…</span></span>
<span><span class="co">#&gt; $ MEM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ MTR <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ CHL <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ COL <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, R, R, R, R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, …</span></span>
<span><span class="co">#&gt; $ MUP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ RIF <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R, R, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, <span style="color: #BB0000;">NA</span>, R, R, R, R, R, <span style="color: #BB0000;">N</span>…</span></span></code></pre></div>
<span><span class="co">#&gt; $ date <span style="color: #949494; font-style: italic;">&lt;date&gt;</span> 2002-01-02<span style="color: #949494;">, </span>2002-01-03<span style="color: #949494;">, </span>2002-01-07<span style="color: #949494;">, </span>2002-01-07<span style="color: #949494;">, </span>2002-01-13<span style="color: #949494;">, </span>2…</span></span>
<span><span class="co">#&gt; $ patient <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "A77334"<span style="color: #949494;">, </span>"A77334"<span style="color: #949494;">, </span>"067927"<span style="color: #949494;">, </span>"067927"<span style="color: #949494;">, </span>"067927"<span style="color: #949494;">, </span>"067927"<span style="color: #949494;">, </span>"4…</span></span>
<span><span class="co">#&gt; $ age <span style="color: #949494; font-style: italic;">&lt;dbl&gt;</span> 65<span style="color: #949494;">, </span>65<span style="color: #949494;">, </span>45<span style="color: #949494;">, </span>45<span style="color: #949494;">, </span>45<span style="color: #949494;">, </span>45<span style="color: #949494;">, </span>78<span style="color: #949494;">, </span>78<span style="color: #949494;">, </span>45<span style="color: #949494;">, </span>79<span style="color: #949494;">, </span>67<span style="color: #949494;">, </span>67<span style="color: #949494;">, </span>71<span style="color: #949494;">, </span>71<span style="color: #949494;">, </span>75<span style="color: #949494;">, </span>50…</span></span>
<span><span class="co">#&gt; $ gender <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "F"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"M"<span style="color: #949494;">, </span>"M"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"F"<span style="color: #949494;">, </span>"M"<span style="color: #949494;">, </span>"M"<span style="color: #949494;">, </span>"M…</span></span>
<span><span class="co">#&gt; $ ward <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> "Clinical"<span style="color: #949494;">, </span>"Clinical"<span style="color: #949494;">, </span>"ICU"<span style="color: #949494;">, </span>"ICU"<span style="color: #949494;">, </span>"ICU"<span style="color: #949494;">, </span>"ICU"<span style="color: #949494;">, </span>"Clinical"…</span></span>
<span><span class="co">#&gt; $ mo <span style="color: #949494; font-style: italic;">&lt;mo&gt;</span> "B_ESCHR_COLI"<span style="color: #949494;">, </span>"B_ESCHR_COLI"<span style="color: #949494;">, </span>"B_STPHY_EPDR"<span style="color: #949494;">, </span>"B_STPHY_EPDR"<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ PEN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ OXA <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ FLC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R…</span></span>
<span><span class="co">#&gt; $ AMX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ AMC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> I<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ AMP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ TZP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ CZO <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ FEP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ CXM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> I<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S…</span></span>
<span><span class="co">#&gt; $ FOX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ CTX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S…</span></span>
<span><span class="co">#&gt; $ CAZ <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>…</span></span>
<span><span class="co">#&gt; $ CRO <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S…</span></span>
<span><span class="co">#&gt; $ GEN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ TOB <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ AMK <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ KAN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ TMP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>…</span></span>
<span><span class="co">#&gt; $ SXT <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ NIT <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ FOS <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ LNZ <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ CIP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S…</span></span>
<span><span class="co">#&gt; $ MFX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ VAN <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>…</span></span>
<span><span class="co">#&gt; $ TEC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span>
<span><span class="co">#&gt; $ TCY <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>I<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>…</span></span>
<span><span class="co">#&gt; $ TGC <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ DOX <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ ERY <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ CLI <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ AZM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>S<span style="color: #949494;">,</span>…</span></span>
<span><span class="co">#&gt; $ IPM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>S<span style="color: #949494;">, </span>S…</span></span>
<span><span class="co">#&gt; $ MEM <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ MTR <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ CHL <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ COL <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>…</span></span>
<span><span class="co">#&gt; $ MUP <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> <span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span>…</span></span>
<span><span class="co">#&gt; $ RIF <span style="color: #949494; font-style: italic;">&lt;sir&gt;</span> R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span><span style="color: #BB0000;">NA</span><span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span>R<span style="color: #949494;">, </span><span style="color: #BB0000;">N</span>…</span></span></code></pre></div>
<p>Now to transform this to a data set with only resistance percentages
per taxonomic order and genus:</p>
<div class="sourceCode" id="cb2"><pre class="downlit sourceCode r">

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<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
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<main id="main" class="col-md-9"><div class="page-header">
<img src="../logo.svg" class="logo" alt=""><h1>Data sets for download / own use</h1>
<h4 data-toc-skip class="date">31 March 2025</h4>
<h4 data-toc-skip class="date">07 April 2025</h4>
<small class="dont-index">Source: <a href="https://github.com/msberends/AMR/blob/main/vignettes/datasets.Rmd" class="external-link"><code>vignettes/datasets.Rmd</code></a></small>
<div class="d-none name"><code>datasets.Rmd</code></div>

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</div>
<div class="section level2">
<h2 class="pkg-version" data-toc-text="2.1.1.9233" id="amr-2119233">AMR 2.1.1.9233<a class="anchor" aria-label="anchor" href="#amr-2119233"></a></h2>
<h2 class="pkg-version" data-toc-text="2.1.1.9234" id="amr-2119234">AMR 2.1.1.9234<a class="anchor" aria-label="anchor" href="#amr-2119234"></a></h2>
<p><em>(this beta version will eventually become v3.0. We’re happy to reach a new major milestone soon, which will be all about the new One Health support! Install this beta using <a href="https://msberends.github.io/AMR/#latest-development-version">the instructions here</a>.)</em></p>
<div class="section level5">
<h5 id="a-new-milestone-amr-v30-with-one-health-support--human--veterinary--environmental-2-1-1-9233">A New Milestone: AMR v3.0 with One Health Support (= Human + Veterinary + Environmental)<a class="anchor" aria-label="anchor" href="#a-new-milestone-amr-v30-with-one-health-support--human--veterinary--environmental-2-1-1-9233"></a></h5>
<h5 id="a-new-milestone-amr-v30-with-one-health-support--human--veterinary--environmental-2-1-1-9234">A New Milestone: AMR v3.0 with One Health Support (= Human + Veterinary + Environmental)<a class="anchor" aria-label="anchor" href="#a-new-milestone-amr-v30-with-one-health-support--human--veterinary--environmental-2-1-1-9234"></a></h5>
<p>This package now supports not only tools for AMR data analysis in clinical settings, but also for veterinary and environmental microbiology. This was made possible through a collaboration with the <a href="https://www.upei.ca/avc" class="external-link">University of Prince Edward Island’s Atlantic Veterinary College</a>, Canada. To celebrate this great improvement of the package, we also updated the package logo to reflect this change.</p>
</div>
<div class="section level3">
<h3 id="breaking-2-1-1-9233">Breaking<a class="anchor" aria-label="anchor" href="#breaking-2-1-1-9233"></a></h3>
<h3 id="breaking-2-1-1-9234">Breaking<a class="anchor" aria-label="anchor" href="#breaking-2-1-1-9234"></a></h3>
<ul><li>Dataset <code>antibiotics</code> has been renamed to <code>antimicrobials</code> as the data set contains more than just antibiotics. Using <code>antibiotics</code> will still work, but now returns a warning.</li>
<li>Removed all functions and references that used the deprecated <code>rsi</code> class, which were all replaced with their <code>sir</code> equivalents over two years ago.</li>
<li>Function <code><a href="../reference/resistance_predict.html">resistance_predict()</a></code> is now deprecated and will be removed in a future version. Use the <code>tidymodels</code> framework instead, for which we <a href="https://msberends.github.io/AMR/articles/AMR_with_tidymodels.html">wrote a basic introduction</a>.</li>
</ul></div>
<div class="section level3">
<h3 id="new-2-1-1-9233">New<a class="anchor" aria-label="anchor" href="#new-2-1-1-9233"></a></h3>
<h3 id="new-2-1-1-9234">New<a class="anchor" aria-label="anchor" href="#new-2-1-1-9234"></a></h3>
<ul><li>
<strong>One Health implementation</strong>
<ul><li>Function <code><a href="../reference/as.sir.html">as.sir()</a></code> now has extensive support for veterinary breakpoints from CLSI. Use <code>breakpoint_type = "animal"</code> and set the <code>host</code> argument to a variable that contains animal species names.</li>
@ -116,7 +116,7 @@
</ul></li>
</ul></div>
<div class="section level3">
<h3 id="changed-2-1-1-9233">Changed<a class="anchor" aria-label="anchor" href="#changed-2-1-1-9233"></a></h3>
<h3 id="changed-2-1-1-9234">Changed<a class="anchor" aria-label="anchor" href="#changed-2-1-1-9234"></a></h3>
<ul><li>SIR interpretation
<ul><li>It is now possible to use column names for argument <code>ab</code>, <code>mo</code>, and <code>uti</code>: <code>as.sir(..., ab = "column1", mo = "column2", uti = "column3")</code>. This greatly improves the flexibility for users.</li>
<li>Users can now set their own criteria (using regular expressions) as to what should be considered S, I, R, SDD, and NI.</li>
@ -195,7 +195,7 @@
<li>Added console colours support of <code>sir</code> class for Positron</li>
</ul></div>
<div class="section level3">
<h3 id="other-2-1-1-9233">Other<a class="anchor" aria-label="anchor" href="#other-2-1-1-9233"></a></h3>
<h3 id="other-2-1-1-9234">Other<a class="anchor" aria-label="anchor" href="#other-2-1-1-9234"></a></h3>
<ul><li>Added Dr. Larisse Bolton and Aislinn Cook as contributors for their fantastic implementation of WISCA in a mathematically solid way</li>
<li>Added Matthew Saab, Dr. Jordan Stull, and Prof. Javier Sanchez as contributors for their tremendous input on veterinary breakpoints and interpretations</li>
<li>Added Prof. Kat Holt, Dr. Jane Hawkey, and Dr. Natacha Couto as contributors for their many suggestions, ideas and bugfixes</li>
@ -204,7 +204,7 @@
<li>Stopped support for SAS (<code>.xpt</code>) files, since their file structure and extremely inefficient and requires more disk space than GitHub allows in a single commit.</li>
</ul></div>
<div class="section level3">
<h3 id="older-versions-2-1-1-9233">Older Versions<a class="anchor" aria-label="anchor" href="#older-versions-2-1-1-9233"></a></h3>
<h3 id="older-versions-2-1-1-9234">Older Versions<a class="anchor" aria-label="anchor" href="#older-versions-2-1-1-9234"></a></h3>
<p>This changelog only contains changes from AMR v3.0 (March 2025) and later.</p>
<ul><li>For prior v2 versions, please see <a href="https://github.com/msberends/AMR/blob/v2.1.1/NEWS.md" class="external-link">our v2 archive</a>.</li>
<li>For prior v1 versions, please see <a href="https://github.com/msberends/AMR/blob/v1.8.2/NEWS.md" class="external-link">our v1 archive</a>.</li>

2
pkgdown.yml
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@ -11,7 +11,7 @@ articles:
PCA: PCA.html
welcome_to_AMR: welcome_to_AMR.html
WHONET: WHONET.html
last_built: 2025-03-31T13:00Z
last_built: 2025-04-07T16:45Z
urls:
reference: https://msberends.github.io/AMR/reference
article: https://msberends.github.io/AMR/articles

2
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/AMR-options.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/AMR.html
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@ -21,7 +21,7 @@ The AMR package is available in English, Chinese, Czech, Danish, Dutch, Finnish,
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/WHOCC.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/WHONET.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/ab_from_text.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/ab_property.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/add_custom_antimicrobials.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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2
reference/add_custom_microorganisms.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

22
reference/age.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -112,16 +112,16 @@
<span class="r-in"><span></span></span>
<span class="r-in"><span><span class="va">df</span></span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> birth_date age age_exact age_at_y2k</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 1 1999-06-30 25 25.75068 0</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 2 1968-01-29 57 57.16712 31</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 3 1965-12-05 59 59.31781 34</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 4 1980-03-01 45 45.08219 19</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 5 1949-11-01 75 75.41096 50</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 6 1947-02-14 78 78.12329 52</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 7 1940-02-19 85 85.10959 59</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 8 1988-01-10 37 37.21918 11</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 9 1997-08-27 27 27.59178 2</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 10 1978-01-26 47 47.17534 21</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 1 1999-06-30 25 25.76986 0</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 2 1968-01-29 57 57.18630 31</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 3 1965-12-05 59 59.33699 34</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 4 1980-03-01 45 45.10137 19</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 5 1949-11-01 75 75.43014 50</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 6 1947-02-14 78 78.14247 52</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 7 1940-02-19 85 85.12877 59</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 8 1988-01-10 37 37.23836 11</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 9 1997-08-27 27 27.61096 2</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> 10 1978-01-26 47 47.19452 21</span>
</code></pre></div>
</div>
</main><aside class="col-md-3"><nav id="toc" aria-label="Table of contents"><h2>On this page</h2>

2
reference/age_groups.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
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16
reference/antibiogram.html
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@ -9,7 +9,7 @@ Adhering to previously described approaches (see Source) and especially the Baye
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -68,7 +68,7 @@ Adhering to previously described approaches (see Source) and especially the Baye
<span> info <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/interactive.html" class="external-link">interactive</a></span><span class="op">(</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span></span>
<span></span>
<span><span class="fu">wisca</span><span class="op">(</span><span class="va">x</span>, antimicrobials <span class="op">=</span> <span class="fu"><a href="https://tidyselect.r-lib.org/reference/where.html" class="external-link">where</a></span><span class="op">(</span><span class="va">is.sir</span><span class="op">)</span>, ab_transform <span class="op">=</span> <span class="st">"name"</span>,</span>
<span> syndromic_group <span class="op">=</span> <span class="cn">NULL</span>, digits <span class="op">=</span> <span class="fl">1</span>,</span>
<span> syndromic_group <span class="op">=</span> <span class="cn">NULL</span>, only_all_tested <span class="op">=</span> <span class="cn">FALSE</span>, digits <span class="op">=</span> <span class="fl">1</span>,</span>
<span> formatting_type <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/options.html" class="external-link">getOption</a></span><span class="op">(</span><span class="st">"AMR_antibiogram_formatting_type"</span>, <span class="fl">14</span><span class="op">)</span>,</span>
<span> col_mo <span class="op">=</span> <span class="cn">NULL</span>, language <span class="op">=</span> <span class="fu"><a href="translate.html">get_AMR_locale</a></span><span class="op">(</span><span class="op">)</span>, combine_SI <span class="op">=</span> <span class="cn">TRUE</span>,</span>
<span> sep <span class="op">=</span> <span class="st">" + "</span>, simulations <span class="op">=</span> <span class="fl">1000</span>, conf_interval <span class="op">=</span> <span class="fl">0.95</span>,</span>
@ -590,9 +590,9 @@ $$p_i = \frac{x_i}{\sum_{j=1}^K x_j}$$</p>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># An Antibiogram (WISCA / 95% CI): 3 × 4</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> `Syndromic Group` `Piperacillin/tazobactam` Piperacillin/tazobactam + Gentam…¹</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">1</span> Clinical 76.5% (60.8-88%) 95.3% (86.4-99.2%) </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">2</span> ICU 60.3% (42.1-80.7%) 90.6% (76.4-98.1%) </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">3</span> Outpatient 66.8% (38.4-91.3%) 89.7% (69.9-99.5%) </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">1</span> Clinical 73.8% (53.8-89.1%) 93% (80.7-99.1%) </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">2</span> ICU 57.6% (31.5-85.2%) 85.5% (64-98.1%) </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">3</span> Outpatient 58.2% (18.1-94.1%) 77.6% (41.8-99.1%) </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># ℹ abbreviated name: ¹​`Piperacillin/tazobactam + Gentamicin`</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># ℹ 1 more variable: `Piperacillin/tazobactam + Tobramycin` &lt;chr&gt;</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># Use `ggplot2::autoplot()` or base R `plot()` to create a plot of this antibiogram,</span></span>
@ -617,9 +617,9 @@ $$p_i = \frac{x_i}{\sum_{j=1}^K x_j}$$</p>
<span class="r-out co"><span class="r-pr">#&gt;</span> </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |Syndromic Group |Piperacillin/tazobactam |</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |:---------------|:-----------------------|</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |Clinical |76% (60-88.6%) |</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |ICU |59.8% (40.7-79.7%) |</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |Outpatient |66.2% (37.9-91.3%) |</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |Clinical |73% (53.9-89.6%) |</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |ICU |56.9% (30.3-84.6%) |</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> |Outpatient |57.3% (19-94.4%) |</span>
<span class="r-in"><span></span></span>
<span class="r-in"><span></span></span>
<span class="r-in"><span><span class="co"># Generate plots with ggplot2 or base R --------------------------------</span></span></span>

2
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@ -17,7 +17,7 @@ my_data_with_all_these_columns %&amp;gt;%
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
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reference/antimicrobials.html
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@ -7,7 +7,7 @@
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@ -7,7 +7,7 @@
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reference/as.av.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
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@ -7,7 +7,7 @@
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reference/as.mic.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
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reference/as.sir.html
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@ -21,7 +21,7 @@ All breakpoints used for interpretation are available in our clinical_breakpoint
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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@ -239,7 +239,7 @@ All breakpoints used for interpretation are available in our clinical_breakpoint
<p>The <code>as.sir()</code> function can work in four ways:</p><ol><li><p>For <strong>cleaning raw / untransformed data</strong>. The data will be cleaned to only contain valid values, namely: <strong>S</strong> for susceptible, <strong>I</strong> for intermediate or 'susceptible, increased exposure', <strong>R</strong> for resistant, <strong>NI</strong> for non-interpretable, and <strong>SDD</strong> for susceptible dose-dependent. Each of these can be set using a <a href="https://rdrr.io/r/base/regex.html" class="external-link">regular expression</a>. Furthermore, <code>as.sir()</code> will try its best to clean with some intelligence. For example, mixed values with SIR interpretations and MIC values such as <code>"&lt;0.25; S"</code> will be coerced to <code>"S"</code>. Combined interpretations for multiple test methods (as seen in laboratory records) such as <code>"S; S"</code> will be coerced to <code>"S"</code>, but a value like <code>"S; I"</code> will return <code>NA</code> with a warning that the input is invalid.</p></li>
<li><p>For <strong>interpreting minimum inhibitory concentration (MIC) values</strong> according to EUCAST or CLSI. You must clean your MIC values first using <code><a href="as.mic.html">as.mic()</a></code>, that also gives your columns the new data class <code><a href="as.mic.html">mic</a></code>. Also, be sure to have a column with microorganism names or codes. It will be found automatically, but can be set manually using the <code>mo</code> argument.</p><ul><li><p>Using <code>dplyr</code>, SIR interpretation can be done very easily with either:</p>
<li><p>For <strong>interpreting minimum inhibitory concentration (MIC) values</strong> according to EUCAST or CLSI. You must clean your MIC values first using <code><a href="as.mic.html">as.mic()</a></code>, that also gives your columns the new data class <code><a href="as.mic.html">mic</a></code>. Also, be sure to have a column with microorganism names or codes. It will be found automatically, but can be set manually using the <code>mo</code> argument.</p><ul><li><p>Example to apply using <code>dplyr</code>:</p>
<p></p><div class="sourceCode r"><pre><code><span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate_all.html" class="external-link">mutate_if</a></span><span class="op">(</span><span class="va">is.mic</span>, <span class="va">as.sir</span><span class="op">)</span></span>
<span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate.html" class="external-link">mutate</a></span><span class="op">(</span><span class="fu"><a href="https://dplyr.tidyverse.org/reference/across.html" class="external-link">across</a></span><span class="op">(</span><span class="fu"><a href="https://tidyselect.r-lib.org/reference/where.html" class="external-link">where</a></span><span class="op">(</span><span class="va">is.mic</span><span class="op">)</span>, <span class="va">as.sir</span><span class="op">)</span><span class="op">)</span></span>
<span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate_all.html" class="external-link">mutate_if</a></span><span class="op">(</span><span class="va">is.mic</span>, <span class="va">as.sir</span>, ab <span class="op">=</span> <span class="st">"column_with_antibiotics"</span>, mo <span class="op">=</span> <span class="st">"column_with_microorganisms"</span><span class="op">)</span></span>
@ -248,8 +248,9 @@ All breakpoints used for interpretation are available in our clinical_breakpoint
<span><span class="co"># for veterinary breakpoints, also set `host`:</span></span>
<span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate_all.html" class="external-link">mutate_if</a></span><span class="op">(</span><span class="va">is.mic</span>, <span class="va">as.sir</span>, host <span class="op">=</span> <span class="st">"column_with_animal_species"</span>, guideline <span class="op">=</span> <span class="st">"CLSI"</span><span class="op">)</span></span></code></pre><p></p></div></li>
<li><p>Operators like "&lt;=" will be stripped before interpretation. When using <code>capped_mic_handling = "conservative"</code>, an MIC value of e.g. "&gt;2" will always return "R", even if the breakpoint according to the chosen guideline is "&gt;=4". This is to prevent that capped values from raw laboratory data would not be treated conservatively. The default behaviour (<code>capped_mic_handling = "standard"</code>) considers "&gt;2" to be lower than "&gt;=4" and might in this case return "S" or "I".</p></li>
<li><p><strong>Note:</strong> When using CLSI as the guideline, MIC values must be log2-based doubling dilutions. Values not in this format, will be automatically rounded up to the nearest log2 level as CLSI instructs, and a warning will be thrown.</p></li>
</ul></li>
<li><p>For <strong>interpreting disk diffusion diameters</strong> according to EUCAST or CLSI. You must clean your disk zones first using <code><a href="as.disk.html">as.disk()</a></code>, that also gives your columns the new data class <code><a href="as.disk.html">disk</a></code>. Also, be sure to have a column with microorganism names or codes. It will be found automatically, but can be set manually using the <code>mo</code> argument.</p><ul><li><p>Using <code>dplyr</code>, SIR interpretation can be done very easily with either:</p>
<li><p>For <strong>interpreting disk diffusion diameters</strong> according to EUCAST or CLSI. You must clean your disk zones first using <code><a href="as.disk.html">as.disk()</a></code>, that also gives your columns the new data class <code><a href="as.disk.html">disk</a></code>. Also, be sure to have a column with microorganism names or codes. It will be found automatically, but can be set manually using the <code>mo</code> argument.</p><ul><li><p>Example to apply using <code>dplyr</code>:</p>
<p></p><div class="sourceCode r"><pre><code><span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate_all.html" class="external-link">mutate_if</a></span><span class="op">(</span><span class="va">is.disk</span>, <span class="va">as.sir</span><span class="op">)</span></span>
<span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate.html" class="external-link">mutate</a></span><span class="op">(</span><span class="fu"><a href="https://dplyr.tidyverse.org/reference/across.html" class="external-link">across</a></span><span class="op">(</span><span class="fu"><a href="https://tidyselect.r-lib.org/reference/where.html" class="external-link">where</a></span><span class="op">(</span><span class="va">is.disk</span><span class="op">)</span>, <span class="va">as.sir</span><span class="op">)</span><span class="op">)</span></span>
<span><span class="va">your_data</span> <span class="op"><a href="https://magrittr.tidyverse.org/reference/pipe.html" class="external-link">%&gt;%</a></span> <span class="fu"><a href="https://dplyr.tidyverse.org/reference/mutate_all.html" class="external-link">mutate_if</a></span><span class="op">(</span><span class="va">is.disk</span>, <span class="va">as.sir</span>, ab <span class="op">=</span> <span class="st">"column_with_antibiotics"</span>, mo <span class="op">=</span> <span class="st">"column_with_microorganisms"</span><span class="op">)</span></span>
@ -287,13 +288,6 @@ All breakpoints used for interpretation are available in our clinical_breakpoint
<p>To determine which isolates are multi-drug resistant, be sure to run <code><a href="mdro.html">mdro()</a></code> (which applies the MDR/PDR/XDR guideline from 2012 at default) on a data set that contains S/I/R values. Read more about <a href="mdro.html">interpreting multidrug-resistant organisms here</a>.</p>
</div>
<div class="section">
<h3 id="machine-readable-clinical-breakpoints">Machine-Readable Clinical Breakpoints<a class="anchor" aria-label="anchor" href="#machine-readable-clinical-breakpoints"></a></h3>
<p>The repository of this package <a href="https://github.com/msberends/AMR/blob/main/data-raw/clinical_breakpoints.txt" class="external-link">contains a machine-readable version</a> of all guidelines. This is a CSV file consisting of 34 376 rows and 14 columns. This file is machine-readable, since it contains one row for every unique combination of the test method (MIC or disk diffusion), the antimicrobial drug and the microorganism. <strong>This allows for easy implementation of these rules in laboratory information systems (LIS)</strong>. Note that it only contains interpretation guidelines for humans - interpretation guidelines from CLSI for animals were removed.</p>
</div>
<div class="section">
<h3 id="other">Other<a class="anchor" aria-label="anchor" href="#other"></a></h3>
@ -309,14 +303,8 @@ All breakpoints used for interpretation are available in our clinical_breakpoint
<h2 id="interpretation-of-sir">Interpretation of SIR<a class="anchor" aria-label="anchor" href="#interpretation-of-sir"></a></h2>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R as shown below (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>):</p><ul><li><p><strong>S - Susceptible, standard dosing regimen</strong><br>
A microorganism is categorised as "Susceptible, standard dosing regimen", when there is a high likelihood of therapeutic success using a standard dosing regimen of the agent.</p></li>
<li><p><strong>I - Susceptible, increased exposure</strong> <em><br>
A microorganism is categorised as "Susceptible, Increased exposure</em>" when there is a high likelihood of therapeutic success because exposure to the agent is increased by adjusting the dosing regimen or by its concentration at the site of infection.</p></li>
<li><p><strong>R = Resistant</strong><br>
A microorganism is categorised as "Resistant" when there is a high likelihood of therapeutic failure even when there is increased exposure.</p><ul><li><p><em>Exposure</em> is a function of how the mode of administration, dose, dosing interval, infusion time, as well as distribution and excretion of the antimicrobial agent will influence the infecting organism at the site of infection.</p></li>
</ul></li>
</ul><p>This AMR package honours this insight. Use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>).</p>
<p>This AMR package follows insight; use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
</div>
<div class="section level2">
<h2 id="download-our-reference-data">Download Our Reference Data<a class="anchor" aria-label="anchor" href="#download-our-reference-data"></a></h2>
@ -668,6 +656,11 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">tobra</span><span style="color: #0000BB;">' (TOB, tobramycin), and '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin) based on column</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">bacteria</span><span style="color: #0000BB;">', </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `mics = (function (x, ...) ...`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> Some MICs were converted to the nearest higher log2 level, following the</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> CLSI interpretation guideline.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -676,6 +669,11 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">tobra</span><span style="color: #0000BB;">' (TOB, tobramycin), and '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin) based on column</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">bacteria</span><span style="color: #0000BB;">', </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `across(...)`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> Some MICs were converted to the nearest higher log2 level, following the</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> CLSI interpretation guideline.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -686,6 +684,11 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Interpreting disk diffusion zones: '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin), </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `cipro = (function (x, ...) ...`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> Some MICs were converted to the nearest higher log2 level, following the</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> CLSI interpretation guideline.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -696,6 +699,11 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Interpreting disk diffusion zones: '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin), </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `across(...)`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> Some MICs were converted to the nearest higher log2 level, following the</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> CLSI interpretation guideline.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -706,6 +714,11 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">tobra</span><span style="color: #0000BB;">' (TOB, tobramycin), and '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin) based on column</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">bacteria</span><span style="color: #0000BB;">', </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `mics = (function (x, ...) ...`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> Some MICs were converted to the nearest higher log2 level, following the</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> CLSI interpretation guideline.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -716,6 +729,11 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">tobra</span><span style="color: #0000BB;">' (TOB, tobramycin), and '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin) based on column</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'</span><span style="color: #0000BB; font-weight: bold;">bacteria</span><span style="color: #0000BB;">', </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `across(...)`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> Some MICs were converted to the nearest higher log2 level, following the</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> CLSI interpretation guideline.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -734,10 +752,12 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #FFAFAF;"> WARNING </span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808;"> • No CLSI 2024 DISK breakpoints available for acetylspiramycin (ASP).</span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There were 2 warnings in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> The first warning was:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `cipro = (function (x, ...) ...`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> The following animal host(s) could not be coerced: "animal_species"</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> Run `dplyr::last_dplyr_warnings()` to see the 1 remaining warning.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -751,10 +771,12 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Interpreting disk diffusion zones: '</span><span style="color: #0000BB; font-weight: bold;">genta</span><span style="color: #0000BB;">' (GEN, gentamicin), </span><span style="color: #0000BB; font-weight: bold;">CLSI 2024</span><span style="color: #0000BB;">...</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #080808; background-color: #5FD7AF;"> OK </span></span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There was 1 warning in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span class="warning">Warning: </span>There were 2 warnings in `mutate()`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> The first warning was:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> In argument: `across(...)`.</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> Caused by warning:</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #BBBB00;">!</span> The following animal host(s) could not be coerced: "animal_species"</span>
<span class="r-wrn co"><span class="r-pr">#&gt;</span> <span style="color: #00BBBB;">ℹ</span> Run `dplyr::last_dplyr_warnings()` to see the 1 remaining warning.</span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> </span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;">ℹ Run </span><span style="color: #00BB00; background-color: #EEEEEE;">sir_interpretation_history()</span><span style="color: #00BB00;"> afterwards to retrieve a logbook with</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #00BB00;"> all the details of the breakpoint interpretations.</span></span>
@ -817,22 +839,22 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-in"><span></span></span>
<span class="r-in"><span><span class="co"># return a 'logbook' about the results:</span></span></span>
<span class="r-in"><span><span class="fu">sir_interpretation_history</span><span class="op">(</span><span class="op">)</span></span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># A tibble: 65 × 16</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> datetime index ab_given mo_given host_given ab mo </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494; font-style: italic;">&lt;dttm&gt;</span> <span style="color: #949494; font-style: italic;">&lt;int&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;ab&gt;</span> <span style="color: #949494; font-style: italic;">&lt;mo&gt;</span> </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 1</span> 2025-03-31 <span style="color: #949494;">13:01:25</span> 1 ampicillin Strep p… human AMP <span style="color: #949494;">B_</span>STRPT<span style="color: #949494;">_</span>PNMN </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 2</span> 2025-03-31 <span style="color: #949494;">13:01:25</span> 1 AMP Escheri… human AMP <span style="color: #949494;">B_</span>[ORD]<span style="color: #949494;">_</span>ENTRBC…</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 3</span> 2025-03-31 <span style="color: #949494;">13:01:25</span> 1 AMP Escheri… human AMP <span style="color: #949494;">B_</span>[ORD]<span style="color: #949494;">_</span>ENTRBC…</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 4</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;"> NA</span> </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 5</span> 2025-03-31 <span style="color: #949494;">13:01:25</span> 1 GEN Escheri… human GEN <span style="color: #949494;">B_</span>[ORD]<span style="color: #949494;">_</span>ENTRBC…</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 6</span> 2025-03-31 <span style="color: #949494;">13:01:26</span> 1 TOB Escheri… human TOB <span style="color: #949494;">B_</span>[ORD]<span style="color: #949494;">_</span>ENTRBC…</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 7</span> 2025-03-31 <span style="color: #949494;">13:01:26</span> 1 AMX B_STRPT… human AMX <span style="color: #949494;">B_</span>STRPT<span style="color: #949494;">_</span>PNMN </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 8</span> 2025-03-31 <span style="color: #949494;">13:01:26</span> 1 AMX B_STRPT… human AMX <span style="color: #949494;">B_</span>STRPT<span style="color: #949494;">_</span>PNMN </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 9</span> 2025-03-31 <span style="color: #949494;">13:01:26</span> 2 AMX B_STRPT… human AMX <span style="color: #949494;">B_</span>STRPT<span style="color: #949494;">_</span>PNMN </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">10</span> 2025-03-31 <span style="color: #949494;">13:01:26</span> 3 AMX B_STRPT… human AMX <span style="color: #949494;">B_</span>STRPT<span style="color: #949494;">_</span>PNMN </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># A tibble: 65 × 17</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> datetime index method ab_given mo_given host_given input_given</span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494; font-style: italic;">&lt;dttm&gt;</span> <span style="color: #949494; font-style: italic;">&lt;int&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> <span style="color: #949494; font-style: italic;">&lt;chr&gt;</span> </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 1</span> 2025-04-07 <span style="color: #949494;">16:46:11</span> 1 DISK ampicillin Strep pneu human 18 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 2</span> 2025-04-07 <span style="color: #949494;">16:46:12</span> 1 DISK AMP Escherich… human 20 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 3</span> 2025-04-07 <span style="color: #949494;">16:46:12</span> 1 DISK AMP Escherich… human 20 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 4</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> <span style="color: #BB0000;">NA</span> </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 5</span> 2025-04-07 <span style="color: #949494;">16:46:12</span> 1 DISK GEN Escherich… human 18 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 6</span> 2025-04-07 <span style="color: #949494;">16:46:12</span> 1 DISK TOB Escherich… human 16 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 7</span> 2025-04-07 <span style="color: #949494;">16:46:13</span> 1 MIC AMX B_STRPT_P… human 2 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 8</span> 2025-04-07 <span style="color: #949494;">16:46:13</span> 1 MIC AMX B_STRPT_P… human 0.01 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;"> 9</span> 2025-04-07 <span style="color: #949494;">16:46:13</span> 2 MIC AMX B_STRPT_P… human 2 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #BCBCBC;">10</span> 2025-04-07 <span style="color: #949494;">16:46:13</span> 3 MIC AMX B_STRPT_P… human 4 </span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># ℹ 55 more rows</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># ℹ 9 more variables: host &lt;chr&gt;, method &lt;chr&gt;, input &lt;chr&gt;, outcome &lt;sir&gt;,</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># notes &lt;chr&gt;, guideline &lt;chr&gt;, ref_table &lt;chr&gt;, uti &lt;lgl&gt;,</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># ℹ 10 more variables: ab &lt;ab&gt;, mo &lt;mo&gt;, host &lt;chr&gt;, input &lt;chr&gt;,</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># outcome &lt;sir&gt;, notes &lt;chr&gt;, guideline &lt;chr&gt;, ref_table &lt;chr&gt;, uti &lt;lgl&gt;,</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> <span style="color: #949494;"># breakpoint_S_R &lt;chr&gt;</span></span>
<span class="r-in"><span></span></span>
<span class="r-in"><span><span class="co"># for single values</span></span></span>

2
reference/atc_online.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/av_from_text.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/av_property.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/availability.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/bug_drug_combinations.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/clinical_breakpoints.html
View File

@ -21,7 +21,7 @@ Use as.sir() to transform MICs or disks measurements to SIR values."><meta prope
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

22
reference/count.html
View File

@ -9,7 +9,7 @@ count_resistant() should be used to count resistant isolates, count_susceptible(
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -123,14 +123,8 @@ count_resistant() should be used to count resistant isolates, count_susceptible(
<h2 id="interpretation-of-sir">Interpretation of SIR<a class="anchor" aria-label="anchor" href="#interpretation-of-sir"></a></h2>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R as shown below (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>):</p><ul><li><p><strong>S - Susceptible, standard dosing regimen</strong><br>
A microorganism is categorised as "Susceptible, standard dosing regimen", when there is a high likelihood of therapeutic success using a standard dosing regimen of the agent.</p></li>
<li><p><strong>I - Susceptible, increased exposure</strong> <em><br>
A microorganism is categorised as "Susceptible, Increased exposure</em>" when there is a high likelihood of therapeutic success because exposure to the agent is increased by adjusting the dosing regimen or by its concentration at the site of infection.</p></li>
<li><p><strong>R = Resistant</strong><br>
A microorganism is categorised as "Resistant" when there is a high likelihood of therapeutic failure even when there is increased exposure.</p><ul><li><p><em>Exposure</em> is a function of how the mode of administration, dose, dosing interval, infusion time, as well as distribution and excretion of the antimicrobial agent will influence the infecting organism at the site of infection.</p></li>
</ul></li>
</ul><p>This AMR package honours this insight. Use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code>count_susceptible()</code> (equal to <code>count_SI()</code>) to count susceptible isolates.</p>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>).</p>
<p>This AMR package follows insight; use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code>count_susceptible()</code> (equal to <code>count_SI()</code>) to count susceptible isolates.</p>
</div>
<div class="section level2">
<h2 id="combination-therapy">Combination Therapy<a class="anchor" aria-label="anchor" href="#combination-therapy"></a></h2>
@ -181,22 +175,12 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-in"><span></span></span>
<span class="r-in"><span><span class="co"># be more specific</span></span></span>
<span class="r-in"><span><span class="fu">count_S</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Using </span><span style="color: #0000BB; background-color: #EEEEEE;">count_S()</span><span style="color: #0000BB;"> is discouraged; use </span><span style="color: #0000BB; background-color: #EEEEEE;">count_susceptible()</span><span style="color: #0000BB;"> instead to also</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">consider "I" and "SDD" being susceptible. This note will be shown once for</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 543</span>
<span class="r-in"><span><span class="fu">count_SI</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Note that </span><span style="color: #0000BB; background-color: #EEEEEE;">count_SI()</span><span style="color: #0000BB;"> will also count dose-dependent susceptibility,</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'SDD'. This note will be shown once for this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 546</span>
<span class="r-in"><span><span class="fu">count_I</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Note that </span><span style="color: #0000BB; background-color: #EEEEEE;">count_I()</span><span style="color: #0000BB;"> will also count dose-dependent susceptibility, 'SDD'.</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">This note will be shown once for this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 3</span>
<span class="r-in"><span><span class="fu">count_IR</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Using </span><span style="color: #0000BB; background-color: #EEEEEE;">count_IR()</span><span style="color: #0000BB;"> is discouraged; use </span><span style="color: #0000BB; background-color: #EEEEEE;">count_resistant()</span><span style="color: #0000BB;"> instead to not</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">consider "I" and "SDD" being resistant. This note will be shown once for</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 807</span>
<span class="r-in"><span><span class="fu">count_R</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 804</span>

2
reference/custom_eucast_rules.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/dosage.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/eucast_rules.html
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@ -9,7 +9,7 @@ To improve the interpretation of the antibiogram before EUCAST rules are applied
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/example_isolates.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/example_isolates_unclean.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/export_ncbi_biosample.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/first_isolate.html
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@ -9,7 +9,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/g.test.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/get_episode.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/ggplot_pca.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/ggplot_sir.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/guess_ab_col.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/index.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/intrinsic_resistant.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/italicise_taxonomy.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/join.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/key_antimicrobials.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/kurtosis.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/like.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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12
reference/mdro.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -234,14 +234,8 @@ Ordered <a href="https://rdrr.io/r/base/factor.html" class="external-link">facto
<h2 id="interpretation-of-sir">Interpretation of SIR<a class="anchor" aria-label="anchor" href="#interpretation-of-sir"></a></h2>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R as shown below (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>):</p><ul><li><p><strong>S - Susceptible, standard dosing regimen</strong><br>
A microorganism is categorised as "Susceptible, standard dosing regimen", when there is a high likelihood of therapeutic success using a standard dosing regimen of the agent.</p></li>
<li><p><strong>I - Susceptible, increased exposure</strong> <em><br>
A microorganism is categorised as "Susceptible, Increased exposure</em>" when there is a high likelihood of therapeutic success because exposure to the agent is increased by adjusting the dosing regimen or by its concentration at the site of infection.</p></li>
<li><p><strong>R = Resistant</strong><br>
A microorganism is categorised as "Resistant" when there is a high likelihood of therapeutic failure even when there is increased exposure.</p><ul><li><p><em>Exposure</em> is a function of how the mode of administration, dose, dosing interval, infusion time, as well as distribution and excretion of the antimicrobial agent will influence the infecting organism at the site of infection.</p></li>
</ul></li>
</ul><p>This AMR package honours this insight. Use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>).</p>
<p>This AMR package follows insight; use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
</div>
<div class="section level2">

2
reference/mean_amr_distance.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/microorganisms.codes.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/microorganisms.groups.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/microorganisms.html
View File

@ -9,7 +9,7 @@ This data set is carefully crafted, yet made 100% reproducible from public and a
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/mo_matching_score.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/mo_property.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/mo_source.html
View File

@ -9,7 +9,7 @@ This is the fastest way to have your organisation (or analysis) specific codes p
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/pca.html
View File

@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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2
reference/plot.html
View File

@ -9,7 +9,7 @@ Especially the scale_*_mic() functions are relevant wrappers to plot MIC values
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
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18
reference/proportion.html
View File

@ -9,7 +9,7 @@ resistance() should be used to calculate resistance, susceptibility() should be
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -194,14 +194,8 @@ resistance() should be used to calculate resistance, susceptibility() should be
<h2 id="interpretation-of-sir">Interpretation of SIR<a class="anchor" aria-label="anchor" href="#interpretation-of-sir"></a></h2>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R as shown below (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>):</p><ul><li><p><strong>S - Susceptible, standard dosing regimen</strong><br>
A microorganism is categorised as "Susceptible, standard dosing regimen", when there is a high likelihood of therapeutic success using a standard dosing regimen of the agent.</p></li>
<li><p><strong>I - Susceptible, increased exposure</strong> <em><br>
A microorganism is categorised as "Susceptible, Increased exposure</em>" when there is a high likelihood of therapeutic success because exposure to the agent is increased by adjusting the dosing regimen or by its concentration at the site of infection.</p></li>
<li><p><strong>R = Resistant</strong><br>
A microorganism is categorised as "Resistant" when there is a high likelihood of therapeutic failure even when there is increased exposure.</p><ul><li><p><em>Exposure</em> is a function of how the mode of administration, dose, dosing interval, infusion time, as well as distribution and excretion of the antimicrobial agent will influence the infecting organism at the site of infection.</p></li>
</ul></li>
</ul><p>This AMR package honours this insight. Use <code>susceptibility()</code> (equal to <code>proportion_SI()</code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>).</p>
<p>This AMR package follows insight; use <code>susceptibility()</code> (equal to <code>proportion_SI()</code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
</div>
<div class="section level2">
<h2 id="see-also">See also<a class="anchor" aria-label="anchor" href="#see-also"></a></h2>
@ -263,16 +257,10 @@ A microorganism is categorised as "Resistant" when there is a high likelihood of
<span class="r-in"><span><span class="fu">proportion_S</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 0.4022222</span>
<span class="r-in"><span><span class="fu">proportion_SI</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Note that </span><span style="color: #0000BB; background-color: #EEEEEE;">proportion_SI()</span><span style="color: #0000BB;"> will also include dose-dependent</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">susceptibility, 'SDD'. This note will be shown once for this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 0.4044444</span>
<span class="r-in"><span><span class="fu">proportion_I</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Note that </span><span style="color: #0000BB; background-color: #EEEEEE;">proportion_I()</span><span style="color: #0000BB;"> will also include dose-dependent susceptibility,</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">'SDD'. This note will be shown once for this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 0.002222222</span>
<span class="r-in"><span><span class="fu">proportion_IR</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">Note that </span><span style="color: #0000BB; background-color: #EEEEEE;">proportion_IR()</span><span style="color: #0000BB;"> will also include dose-dependent</span></span>
<span class="r-msg co"><span class="r-pr">#&gt;</span> <span style="color: #0000BB;">susceptibility, 'SDD'. This note will be shown once for this session.</span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 0.5977778</span>
<span class="r-in"><span><span class="fu">proportion_R</span><span class="op">(</span><span class="va">example_isolates</span><span class="op">$</span><span class="va">AMX</span><span class="op">)</span></span></span>
<span class="r-out co"><span class="r-pr">#&gt;</span> [1] 0.5955556</span>

2
reference/random.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

12
reference/resistance_predict.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">
@ -160,14 +160,8 @@
<h2 id="interpretation-of-sir">Interpretation of SIR<a class="anchor" aria-label="anchor" href="#interpretation-of-sir"></a></h2>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R as shown below (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>):</p><ul><li><p><strong>S - Susceptible, standard dosing regimen</strong><br>
A microorganism is categorised as "Susceptible, standard dosing regimen", when there is a high likelihood of therapeutic success using a standard dosing regimen of the agent.</p></li>
<li><p><strong>I - Susceptible, increased exposure</strong> <em><br>
A microorganism is categorised as "Susceptible, Increased exposure</em>" when there is a high likelihood of therapeutic success because exposure to the agent is increased by adjusting the dosing regimen or by its concentration at the site of infection.</p></li>
<li><p><strong>R = Resistant</strong><br>
A microorganism is categorised as "Resistant" when there is a high likelihood of therapeutic failure even when there is increased exposure.</p><ul><li><p><em>Exposure</em> is a function of how the mode of administration, dose, dosing interval, infusion time, as well as distribution and excretion of the antimicrobial agent will influence the infecting organism at the site of infection.</p></li>
</ul></li>
</ul><p>This AMR package honours this insight. Use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
<p>In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R (<a href="https://www.eucast.org/newsiandr" class="external-link">https://www.eucast.org/newsiandr</a>).</p>
<p>This AMR package follows insight; use <code><a href="proportion.html">susceptibility()</a></code> (equal to <code><a href="proportion.html">proportion_SI()</a></code>) to determine antimicrobial susceptibility and <code><a href="count.html">count_susceptible()</a></code> (equal to <code><a href="count.html">count_SI()</a></code>) to count susceptible isolates.</p>
</div>
<div class="section level2">
<h2 id="see-also">See also<a class="anchor" aria-label="anchor" href="#see-also"></a></h2>

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reference/skewness.html
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@ -9,7 +9,7 @@ When negative ('left-skewed'): the left tail is longer; the mass of the distribu
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/top_n_microorganisms.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
reference/translate.html
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@ -7,7 +7,7 @@
<a class="navbar-brand me-2" href="../index.html">AMR (for R)</a>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9233</small>
<small class="nav-text text-muted me-auto" data-bs-toggle="tooltip" data-bs-placement="bottom" title="">2.1.1.9234</small>
<button class="navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar" aria-controls="navbar" aria-expanded="false" aria-label="Toggle navigation">

2
search.json
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