The former kingdoms Bacteria and Archaea are now each divided into four kingdoms with new top-level domains ‘Bacteria’ and ‘Archaea’ (Göker and Oren, 2024, DOI: 10.1099/ijsem.0.006242). Following this, a new domain column in the microorganisms data set was added, and more importantly, mo_kingdom() now returns the formal kingdom (e.g. "Pseudomonadati" instead of "Bacteria"). Use mo_domain() for the old behaviour. For non-prokaryotic kingdoms (Fungi, Protozoa, etc.), kingdom and domain are identical.
Faster parallel computing via the future package for as.sir() and wisca(): a non-sequential plan (e.g. future::plan(future::multisession)) must be active before using parallel = TRUE.
-
New
+
New
EUCAST 2026 and CLSI 2026 breakpoints: over 5,700 new breakpoints added to the clinical_breakpoints data set; EUCAST 2026 is now the default for all MIC and disk diffusion interpretations
Wildtype/Non-wildtype (WT/NWT) output when using ECOFF-based interpretation, by setting breakpoint_type = "ECOFF" in as.sir(); WT/NWT results are fully supported in all resistance/susceptibility functions and plots (#254)
@@ -74,7 +74,7 @@
New wisca_plot() to assess the susceptibility and incidence distributions from the Monte Carlo simulations
Input of the form "X complex" now falls back to "X" when the complex is not a distinct taxon in the database, preventing NA results for valid clinical descriptions such as "Proteus vulgaris complex" (#287)
Abbreviated-genus input (e.g. "S. apiospermum") now correctly ranks candidates whose species epithet exactly matches the input above more-prevalent organisms whose species does not match; fixes "S. apiospermum" resolving to Staphylococcus instead of Scedosporium apiospermum (#288)
+
Abbreviated-genus input for species that have subspecies (e.g. "P. ovale") now collapses to the species-rank record instead of incorrectly matching a more-prevalent organism; explicit subspecies queries (e.g. "P. ovale curtisi") are preserved (#288)
get_author_year() in the microorganism reproduction script now strips emend. and everything after it, so ref reflects the combination authority rather than the emendation author (e.g. Rhodococcus equi now returns “Goodfellow et al., 1977” instead of “Nouioui et al., 2018”)
@@ -102,7 +103,7 @@
-
Updated
+
Updated
top_n_microorganisms(): new property_for_each argument for sub-grouping within top n groups; rank ordering enforced (only lower taxonomic ranks allowed); fixed property = NULL not being accepted; inner filter now tracks original row indices to prevent cross-group contamination
Taxonomic update for all microorganisms, now updated to June 2026
diff --git a/news/index.md b/news/index.md
index 5fac2c13f..784d81764 100644
--- a/news/index.md
+++ b/news/index.md
@@ -1,6 +1,6 @@
# Changelog
-## AMR 3.0.1.9079
+## AMR 3.0.1.9080
Planned as v3.1.0, end of June 2026.
@@ -117,6 +117,11 @@ Planned as v3.1.0, end of June 2026.
`"S. apiospermum"` resolving to *Staphylococcus* instead of
*Scedosporium apiospermum*
([\#288](https://github.com/msberends/AMR/issues/288))
+ - Abbreviated-genus input for species that have subspecies
+ (e.g. `"P. ovale"`) now collapses to the species-rank record instead
+ of incorrectly matching a more-prevalent organism; explicit
+ subspecies queries (e.g. `"P. ovale curtisi"`) are preserved
+ ([\#288](https://github.com/msberends/AMR/issues/288))
- `get_author_year()` in the microorganism reproduction script now
strips `emend.` and everything after it, so `ref` reflects the
combination authority rather than the emendation author
diff --git a/pkgdown.yml b/pkgdown.yml
index 120c62ce1..aa29fa035 100644
--- a/pkgdown.yml
+++ b/pkgdown.yml
@@ -10,7 +10,7 @@ articles:
PCA: PCA.html
WHONET: WHONET.html
WISCA: WISCA.html
-last_built: 2026-06-27T12:34Z
+last_built: 2026-06-27T13:26Z
urls:
reference: https://amr-for-r.org/reference
article: https://amr-for-r.org/articles
diff --git a/reference/AMR-deprecated.html b/reference/AMR-deprecated.html
index a154ba60c..daa00d63c 100644
--- a/reference/AMR-deprecated.html
+++ b/reference/AMR-deprecated.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/AMR-options.html b/reference/AMR-options.html
index 98d2f16cb..28bd9568b 100644
--- a/reference/AMR-options.html
+++ b/reference/AMR-options.html
@@ -9,7 +9,7 @@ options(AMR_guideline = "CLSI")'>AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/AMR.html b/reference/AMR.html
index b5dd82df7..c323ce97b 100644
--- a/reference/AMR.html
+++ b/reference/AMR.html
@@ -21,7 +21,7 @@ The AMR package is available in English, Arabic, Bengali, Chinese, Czech, Danish
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/WHOCC.html b/reference/WHOCC.html
index 3ced5e6f8..81e17d0b2 100644
--- a/reference/WHOCC.html
+++ b/reference/WHOCC.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/WHONET.html b/reference/WHONET.html
index dc74f04f0..6868b427b 100644
--- a/reference/WHONET.html
+++ b/reference/WHONET.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/ab_from_text.html b/reference/ab_from_text.html
index 1641beb3c..9ae6a7dfd 100644
--- a/reference/ab_from_text.html
+++ b/reference/ab_from_text.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/ab_property.html b/reference/ab_property.html
index a9de10f4b..ed0ab29d9 100644
--- a/reference/ab_property.html
+++ b/reference/ab_property.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/add_custom_antimicrobials.html b/reference/add_custom_antimicrobials.html
index 0e49d82db..88512b284 100644
--- a/reference/add_custom_antimicrobials.html
+++ b/reference/add_custom_antimicrobials.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/add_custom_microorganisms.html b/reference/add_custom_microorganisms.html
index 7eab3763c..138d377f6 100644
--- a/reference/add_custom_microorganisms.html
+++ b/reference/add_custom_microorganisms.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/age.html b/reference/age.html
index df19b9ce2..f68bc7cf9 100644
--- a/reference/age.html
+++ b/reference/age.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/age_groups.html b/reference/age_groups.html
index 5f1c3cc57..130b14e71 100644
--- a/reference/age_groups.html
+++ b/reference/age_groups.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/amr-tidymodels.html b/reference/amr-tidymodels.html
index d0d33356f..5a9ad869a 100644
--- a/reference/amr-tidymodels.html
+++ b/reference/amr-tidymodels.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/amr_course.html b/reference/amr_course.html
index 592d3b40e..0a768f903 100644
--- a/reference/amr_course.html
+++ b/reference/amr_course.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/antibiogram.html b/reference/antibiogram.html
index 228619fea..1e6abef5f 100644
--- a/reference/antibiogram.html
+++ b/reference/antibiogram.html
@@ -13,7 +13,7 @@ All antibiogram types adhere to previously described approaches (see Source), an
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/antimicrobial_selectors.html b/reference/antimicrobial_selectors.html
index 4a75fe619..b8e973aea 100644
--- a/reference/antimicrobial_selectors.html
+++ b/reference/antimicrobial_selectors.html
@@ -17,7 +17,7 @@ my_data_with_all_these_columns %>%
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/antimicrobials.html b/reference/antimicrobials.html
index 4c3e1c466..8d0a707ad 100644
--- a/reference/antimicrobials.html
+++ b/reference/antimicrobials.html
@@ -9,7 +9,7 @@ The antibiotics data set has been renamed to antimicrobials. The old name will b
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/as.ab.html b/reference/as.ab.html
index 90734422c..f76f387aa 100644
--- a/reference/as.ab.html
+++ b/reference/as.ab.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/as.av.html b/reference/as.av.html
index 0401c8da2..a2fddeb0f 100644
--- a/reference/as.av.html
+++ b/reference/as.av.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/as.disk.html b/reference/as.disk.html
index bdcb5b0f5..a81853b29 100644
--- a/reference/as.disk.html
+++ b/reference/as.disk.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/as.mic.html b/reference/as.mic.html
index 832f417a7..105bfd9a5 100644
--- a/reference/as.mic.html
+++ b/reference/as.mic.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/as.mo.html b/reference/as.mo.html
index 777a27a62..9a4024d15 100644
--- a/reference/as.mo.html
+++ b/reference/as.mo.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/as.sir.html b/reference/as.sir.html
index d4ac640af..0104ef591 100644
--- a/reference/as.sir.html
+++ b/reference/as.sir.html
@@ -9,7 +9,7 @@ Breakpoints are currently implemented from EUCAST 2011-2026 and CLSI 2011-2026,
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
@@ -462,10 +462,10 @@ Breakpoints are currently implemented from EUCAST 2011-2026 and CLSI 2011-2026,
#># A tibble: 4 × 18#> datetime index method ab_given mo_given host_given input_given#><dttm><int><chr><chr><chr><chr><chr>
-#>1 2026-06-27 12:37:06 1 MIC amoxicillin Escherich… human 8
-#>2 2026-06-27 12:37:06 1 MIC cipro Escherich… human 0.256
-#>3 2026-06-27 12:37:06 1 DISK tobra Escherich… human 16
-#>4 2026-06-27 12:37:07 1 DISK genta Escherich… human 18
+#>1 2026-06-27 13:28:18 1 MIC amoxicillin Escherich… human 8
+#>2 2026-06-27 13:28:18 1 MIC cipro Escherich… human 0.256
+#>3 2026-06-27 13:28:19 1 DISK tobra Escherich… human 16
+#>4 2026-06-27 13:28:19 1 DISK genta Escherich… human 18 #># ℹ 11 more variables: ab <ab>, mo <mo>, host <chr>, input <chr>,#># outcome <sir>, notes <chr>, guideline <chr>, ref_table <chr>, uti <lgl>,#># breakpoint_S_R <chr>, site <chr>
diff --git a/reference/as.sir.md b/reference/as.sir.md
index e1d7bcedc..6b1113b6b 100644
--- a/reference/as.sir.md
+++ b/reference/as.sir.md
@@ -712,10 +712,10 @@ sir_interpretation_history()
#> # A tibble: 4 × 18
#> datetime index method ab_given mo_given host_given input_given
#>
-#> 1 2026-06-27 12:37:06 1 MIC amoxicillin Escherich… human 8
-#> 2 2026-06-27 12:37:06 1 MIC cipro Escherich… human 0.256
-#> 3 2026-06-27 12:37:06 1 DISK tobra Escherich… human 16
-#> 4 2026-06-27 12:37:07 1 DISK genta Escherich… human 18
+#> 1 2026-06-27 13:28:18 1 MIC amoxicillin Escherich… human 8
+#> 2 2026-06-27 13:28:18 1 MIC cipro Escherich… human 0.256
+#> 3 2026-06-27 13:28:19 1 DISK tobra Escherich… human 16
+#> 4 2026-06-27 13:28:19 1 DISK genta Escherich… human 18
#> # ℹ 11 more variables: ab , mo , host , input ,
#> # outcome , notes , guideline , ref_table , uti ,
#> # breakpoint_S_R , site
diff --git a/reference/atc_online.html b/reference/atc_online.html
index 3cfe6e404..dc9ad0f94 100644
--- a/reference/atc_online.html
+++ b/reference/atc_online.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/av_from_text.html b/reference/av_from_text.html
index 6c8a333ca..ab392f1eb 100644
--- a/reference/av_from_text.html
+++ b/reference/av_from_text.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/av_property.html b/reference/av_property.html
index 090936f3a..e099a5983 100644
--- a/reference/av_property.html
+++ b/reference/av_property.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/availability.html b/reference/availability.html
index 9a77b345a..e0592f862 100644
--- a/reference/availability.html
+++ b/reference/availability.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/bug_drug_combinations.html b/reference/bug_drug_combinations.html
index 5e3821b8c..ff2af912b 100644
--- a/reference/bug_drug_combinations.html
+++ b/reference/bug_drug_combinations.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/clinical_breakpoints.html b/reference/clinical_breakpoints.html
index 26e74fb5d..025cb95ce 100644
--- a/reference/clinical_breakpoints.html
+++ b/reference/clinical_breakpoints.html
@@ -21,7 +21,7 @@ Use as.sir() to transform MICs or disks measurements to SIR values.">AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/count.html b/reference/count.html
index b0af3b2b6..8414cc4f4 100644
--- a/reference/count.html
+++ b/reference/count.html
@@ -9,7 +9,7 @@ count_resistant() should be used to count resistant isolates, count_susceptible(
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/custom_interpretive_rules.html b/reference/custom_interpretive_rules.html
index 7a16e0410..3da1bc8a3 100644
--- a/reference/custom_interpretive_rules.html
+++ b/reference/custom_interpretive_rules.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/custom_mdro_guideline.html b/reference/custom_mdro_guideline.html
index 6c6d14957..b25687319 100644
--- a/reference/custom_mdro_guideline.html
+++ b/reference/custom_mdro_guideline.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/dosage.html b/reference/dosage.html
index b42684feb..57272d088 100644
--- a/reference/dosage.html
+++ b/reference/dosage.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/esbl_isolates.html b/reference/esbl_isolates.html
index 0ab1dc6c4..fd7195052 100644
--- a/reference/esbl_isolates.html
+++ b/reference/esbl_isolates.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/example_isolates.html b/reference/example_isolates.html
index d3a8ec6f8..dc597067f 100644
--- a/reference/example_isolates.html
+++ b/reference/example_isolates.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/example_isolates_unclean.html b/reference/example_isolates_unclean.html
index 932cbc0b4..269a72488 100644
--- a/reference/example_isolates_unclean.html
+++ b/reference/example_isolates_unclean.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/export_ncbi_biosample.html b/reference/export_ncbi_biosample.html
index a91a03e9c..c4299abc3 100644
--- a/reference/export_ncbi_biosample.html
+++ b/reference/export_ncbi_biosample.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/first_isolate.html b/reference/first_isolate.html
index 64d9665b2..b48abe21a 100644
--- a/reference/first_isolate.html
+++ b/reference/first_isolate.html
@@ -9,7 +9,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/g.test.html b/reference/g.test.html
index 808abfbfd..0d70f11ce 100644
--- a/reference/g.test.html
+++ b/reference/g.test.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/get_episode.html b/reference/get_episode.html
index 4dc5f274b..e7eadd436 100644
--- a/reference/get_episode.html
+++ b/reference/get_episode.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/ggplot_pca.html b/reference/ggplot_pca.html
index 5522c04b0..8b19d8341 100644
--- a/reference/ggplot_pca.html
+++ b/reference/ggplot_pca.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/ggplot_sir.html b/reference/ggplot_sir.html
index 1284f41a8..d05b3986d 100644
--- a/reference/ggplot_sir.html
+++ b/reference/ggplot_sir.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/guess_ab_col.html b/reference/guess_ab_col.html
index 6b1de097e..266f38872 100644
--- a/reference/guess_ab_col.html
+++ b/reference/guess_ab_col.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/index.html b/reference/index.html
index df800790a..7df2c26e4 100644
--- a/reference/index.html
+++ b/reference/index.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/interpretive_rules.html b/reference/interpretive_rules.html
index 5b496dd6f..96139b8ca 100644
--- a/reference/interpretive_rules.html
+++ b/reference/interpretive_rules.html
@@ -9,7 +9,7 @@ To improve the interpretation of the antibiogram before CLSI/EUCAST interpretive
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/intrinsic_resistant.html b/reference/intrinsic_resistant.html
index 684359e1f..a841678b8 100644
--- a/reference/intrinsic_resistant.html
+++ b/reference/intrinsic_resistant.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/italicise_taxonomy.html b/reference/italicise_taxonomy.html
index 31bf5773d..bba1b0212 100644
--- a/reference/italicise_taxonomy.html
+++ b/reference/italicise_taxonomy.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/join.html b/reference/join.html
index 48d76e711..a6a0303f1 100644
--- a/reference/join.html
+++ b/reference/join.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/key_antimicrobials.html b/reference/key_antimicrobials.html
index ec233f786..59f863b36 100644
--- a/reference/key_antimicrobials.html
+++ b/reference/key_antimicrobials.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/kurtosis.html b/reference/kurtosis.html
index dd50d894e..662cf3de7 100644
--- a/reference/kurtosis.html
+++ b/reference/kurtosis.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/like.html b/reference/like.html
index 211f25ba1..057769749 100644
--- a/reference/like.html
+++ b/reference/like.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/mdro.html b/reference/mdro.html
index fcad6e26c..c40bf8b9c 100644
--- a/reference/mdro.html
+++ b/reference/mdro.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/mean_amr_distance.html b/reference/mean_amr_distance.html
index e51e71ddb..fe5c0aad6 100644
--- a/reference/mean_amr_distance.html
+++ b/reference/mean_amr_distance.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/microorganisms.codes.html b/reference/microorganisms.codes.html
index 9da89225e..3df58eac7 100644
--- a/reference/microorganisms.codes.html
+++ b/reference/microorganisms.codes.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
diff --git a/reference/microorganisms.groups.html b/reference/microorganisms.groups.html
index 0baac1118..a70d51e24 100644
--- a/reference/microorganisms.groups.html
+++ b/reference/microorganisms.groups.html
@@ -7,7 +7,7 @@
AMR (for R)
- 3.0.1.9079
+ 3.0.1.9080
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@@ -9,7 +9,7 @@ This data set is carefully crafted, yet made 100% reproducible from public and a
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diff --git a/reference/mo_matching_score.html b/reference/mo_matching_score.html
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diff --git a/reference/mo_property.html b/reference/mo_property.html
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diff --git a/reference/mo_source.html b/reference/mo_source.html
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@@ -9,7 +9,7 @@ This is the fastest way to have your organisation (or analysis) specific codes p
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diff --git a/reference/pca.html b/reference/pca.html
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@@ -9,7 +9,7 @@ Especially the scale_*_mic() functions are relevant wrappers to plot MIC values
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diff --git a/reference/proportion.html b/reference/proportion.html
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@@ -9,7 +9,7 @@ resistance() should be used to calculate resistance, susceptibility() should be
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diff --git a/reference/random.html b/reference/random.html
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diff --git a/reference/resistance_predict.html b/reference/resistance_predict.html
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diff --git a/reference/skewness.html b/reference/skewness.html
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diff --git a/reference/top_n_microorganisms.html b/reference/top_n_microorganisms.html
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diff --git a/reference/translate.html b/reference/translate.html
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diff --git a/search.json b/search.json
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-[{"path":"https://amr-for-r.org/CLAUDE.html","id":null,"dir":"","previous_headings":"","what":"CLAUDE.md — AMR R Package","title":"CLAUDE.md — AMR R Package","text":"file provides context Claude Code working repository.","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"project-overview","dir":"","previous_headings":"","what":"Project Overview","title":"CLAUDE.md — AMR R Package","text":"AMR zero-dependency R package antimicrobial resistance (AMR) data analysis using One Health approach. peer-reviewed, used 175+ countries, supports 28 languages. Key capabilities: - SIR (Susceptible/Intermediate/Resistant) classification using EUCAST 2011–2025 CLSI 2011–2025 breakpoints - Antibiogram generation: traditional, combined, syndromic, WISCA - Microorganism taxonomy database (~79,000 species) - Antimicrobial drug database (~620 drugs) - Multi-drug resistant organism (MDRO) classification - First-isolate identification - Minimum Inhibitory Concentration (MIC) disk diffusion handling - Multilingual output (28 languages)","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"common-commands","dir":"","previous_headings":"","what":"Common Commands","title":"CLAUDE.md — AMR R Package","text":"commands run inside R session: shell:","code":"# Rebuild documentation (roxygen2 → .Rd files + NAMESPACE) devtools::document() # Run all tests devtools::test() # Full package check (CRAN-level: docs + tests + checks) devtools::check() # Build pkgdown website locally pkgdown::build_site() # Code coverage report covr::package_coverage() # CRAN check from parent directory R CMD check AMR"},{"path":"https://amr-for-r.org/CLAUDE.html","id":"repository-structure","dir":"","previous_headings":"","what":"Repository Structure","title":"CLAUDE.md — AMR R Package","text":"","code":"R/ # All R source files (62 files, ~28,000 lines) man/ # Auto-generated .Rd documentation (do not edit manually) tests/testthat/ # testthat test files (test-*.R) and helper-functions.R data/ # Pre-compiled .rda datasets data-raw/ # Scripts used to generate data/ files vignettes/ # Rmd vignette articles inst/ # Installed files (translations, etc.) _pkgdown.yml # pkgdown website configuration"},{"path":"https://amr-for-r.org/CLAUDE.html","id":"r-source-file-conventions","dir":"","previous_headings":"","what":"R Source File Conventions","title":"CLAUDE.md — AMR R Package","text":"Naming conventions R/: Key source files: aa_helper_functions.R / aa_helper_pm_functions.R — internal utility functions (large; ~63 KB ~37 KB) aa_globals.R — global constants breakpoint lookup structures aa_options.R — amr_options() / get_AMR_option() system mo.R / mo_property.R — microorganism lookup properties ab.R / ab_property.R — antimicrobial drug functions av.R / av_property.R — antiviral drug functions sir.R / sir_calc.R / sir_df.R — SIR classification engine mic.R / disk.R — MIC disk diffusion classes antibiogram.R — antibiogram generation (traditional, combined, syndromic, WISCA) first_isolate.R — first-isolate identification algorithms mdro.R — MDRO classification (EUCAST, CLSI, CDC, custom guidelines) amr_selectors.R — tidyselect helpers selecting AMR columns interpretive_rules.R / custom_eucast_rules.R — clinical interpretation rules translate.R — 28-language translation system ggplot_sir.R / ggplot_pca.R / plotting.R — visualisation functions","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"code-style","dir":"","previous_headings":"","what":"Code Style","title":"CLAUDE.md — AMR R Package","text":"Follow tidyverse style guide precisely. Key rules: 2-space indentation; tabs <- assignment, = Spaces around binary operators commas; spaces inside parentheses function call must break across lines, place first argument new line indented 2 spaces, put closing ) line — never align arguments opening parenthesis (hanging/forced mid-line indentation)","code":"# good stop_( \"some long message part one \", \"part two\" ) # bad — forces indentation to match the opening parenthesis stop_(\"some long message part one \", \"part two\")"},{"path":"https://amr-for-r.org/CLAUDE.html","id":"custom-s3-classes","dir":"","previous_headings":"","what":"Custom S3 Classes","title":"CLAUDE.md — AMR R Package","text":"package defines five S3 classes full print/format/plot/vctrs support:","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"data-files","dir":"","previous_headings":"","what":"Data Files","title":"CLAUDE.md — AMR R Package","text":"Pre-compiled data/ (edit directly; regenerate via data-raw/ scripts):","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"zero-dependency-design","dir":"","previous_headings":"","what":"Zero-Dependency Design","title":"CLAUDE.md — AMR R Package","text":"package Imports DESCRIPTION. optional integrations (ggplot2, dplyr, data.table, tidymodels, cli, crayon, etc.) listed Suggests guarded : Never add packages Imports. new functionality requires external package, add Suggests guard usage appropriately.","code":"if (requireNamespace(\"pkg\", quietly = TRUE)) { ... }"},{"path":"https://amr-for-r.org/CLAUDE.html","id":"testing","dir":"","previous_headings":"","what":"Testing","title":"CLAUDE.md — AMR R Package","text":"Framework: testthat (R ≥ 3.1); legacy tinytest used R 3.0–3.6 CI Test files: tests/testthat/test-*.R Helpers: tests/testthat/helper-functions.R CI matrix: GitHub Actions across Windows / macOS / Linux × R devel / release / oldrel-1 oldrel-4 Coverage: covr (files excluded: atc_online.R, mo_source.R, translate.R, resistance_predict.R, zz_deprecated.R, helper files, zzz.R)","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"documentation","dir":"","previous_headings":"","what":"Documentation","title":"CLAUDE.md — AMR R Package","text":"exported functions use roxygen2 blocks (RoxygenNote: 7.3.3, markdown enabled) Run devtools::document() change roxygen comments Never edit files man/ directly — auto-generated Vignettes live vignettes/ .Rmd files pkgdown website configured _pkgdown.yml","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"versioning","dir":"","previous_headings":"","what":"Versioning","title":"CLAUDE.md — AMR R Package","text":"Version format: major.minor.patch.dev (e.g., 3.0.1.9021) Development versions use .9xxx suffix Stable CRAN releases drop dev suffix (e.g., 3.0.1) NEWS.md uses sections New, Fixes, Updates GitHub issue references (#NNN)","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"version-and-date-bump-required-for-every-pr","dir":"","previous_headings":"Versioning","what":"Version and date bump required for every PR","title":"CLAUDE.md — AMR R Package","text":"PRs squash-merged, PR lands exactly one commit default branch. Version numbers kept sync cumulative commit count since last released tag. Therefore exactly one version bump allowed per PR, regardless many intermediate commits made branch.","code":""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"computing-the-correct-version-number","dir":"","previous_headings":"Versioning > Version and date bump required for every PR","what":"Computing the correct version number","title":"CLAUDE.md — AMR R Package","text":"First, ensure git gh installed — required version computation pushing changes. Install missing anything else: run following repo root determine version string use: + 1 accounts fact PR’s squash commit yet default branch. Set files resulting version string (per PR, even across multiple commits): DESCRIPTION — Version: field NEWS.md — replace line 1 (# AMR heading) new version number; create new section. NEWS.md continuous log entire current x.y.z.9nnn development series: changes since last stable release accumulate single heading. updating line 1, append new change bullet appropriate sub-heading (### New, ### Fixes, ### Updates). Style rules NEWS.md entries: extremely concise — one short line per item end full stop (period) verbose explanations; just essential fact git describe fails (e.g. tags exist environment), fall back reading current version DESCRIPTION adding 1 last numeric component — bump already made PR.","code":"which git || apt-get install -y git which gh || apt-get install -y gh # Also ensure all tags are fetched so git describe works git fetch --tags currenttag=$(git describe --tags --abbrev=0 | sed 's/v//') currenttagfull=$(git describe --tags --abbrev=0) defaultbranch=$(git branch | cut -c 3- | grep -E '^master$|^main$') git fetch origin ${defaultbranch} --quiet currentcommit=$(git rev-list --count ${currenttagfull}..origin/${defaultbranch}) currentversion=\"${currenttag}.$((currentcommit + 9001 + 1))\" echo \"$currentversion\""},{"path":"https://amr-for-r.org/CLAUDE.html","id":"date-field","dir":"","previous_headings":"Versioning > Version and date bump required for every PR","what":"Date field","title":"CLAUDE.md — AMR R Package","text":"Date: field DESCRIPTION must reflect date last commit PR (first), ISO format. Update every commit always current:","code":"Date: 2026-03-07"},{"path":"https://amr-for-r.org/CLAUDE.html","id":"internal-state","dir":"","previous_headings":"","what":"Internal State","title":"CLAUDE.md — AMR R Package","text":"package uses private AMR_env environment (created aa_globals.R) caching expensive lookups (e.g., microorganism matching scores, breakpoint tables). avoids re-computation within session.","code":""},{"path":"https://amr-for-r.org/articles/AMR.html","id":"introduction","dir":"Articles","previous_headings":"","what":"Introduction","title":"Conduct AMR data analysis","text":"Conducting AMR data analysis unfortunately requires -depth knowledge different scientific fields, makes hard right. least, requires: Good questions (always start !) reliable data thorough understanding (clinical) epidemiology, understand clinical epidemiological relevance possible bias results thorough understanding (clinical) microbiology/infectious diseases, understand microorganisms causal infections implications pharmaceutical treatment, well understanding intrinsic acquired microbial resistance Experience data analysis microbiological tests results, understand determination limitations MIC values interpretations SIR values Availability biological taxonomy microorganisms probably normalisation factors pharmaceuticals, defined daily doses (DDD) Available (inter-)national guidelines, profound methods apply course, instantly provide knowledge experience. AMR package, aimed providing (1) tools simplify antimicrobial resistance data cleaning, transformation analysis, (2) methods easily incorporate international guidelines (3) scientifically reliable reference data, including requirements mentioned . AMR package enables standardised reproducible AMR data analysis, application evidence-based rules, determination first isolates, translation various codes microorganisms antimicrobial drugs, determination (multi-drug) resistant microorganisms, calculation antimicrobial resistance, prevalence future trends.","code":""},{"path":"https://amr-for-r.org/articles/AMR.html","id":"preparation","dir":"Articles","previous_headings":"","what":"Preparation","title":"Conduct AMR data analysis","text":"tutorial, create fake demonstration data work . can skip Cleaning data already data ready. start analysis, try make structure data generally look like :","code":""},{"path":"https://amr-for-r.org/articles/AMR.html","id":"needed-r-packages","dir":"Articles","previous_headings":"Preparation","what":"Needed R packages","title":"Conduct AMR data analysis","text":"many uses R, need additional packages AMR data analysis. package works closely together tidyverse packages dplyr ggplot2 RStudio. tidyverse tremendously improves way conduct data science - allows natural way writing syntaxes creating beautiful plots R. also use cleaner package, can used cleaning data creating frequency tables. AMR package contains data set example_isolates_unclean, might look data users extracted laboratory systems: AMR data analysis, like microorganism column contain valid, --date taxonomy, antibiotic columns cleaned SIR values well.","code":"library(dplyr) library(ggplot2) library(AMR) # (if not yet installed, install with:) # install.packages(c(\"dplyr\", \"ggplot2\", \"AMR\")) example_isolates_unclean #> # A tibble: 3,000 × 8 #> patient_id hospital date bacteria AMX AMC CIP GEN #> #> 1 J3 A 2012-11-21 E. coli R I S S #> 2 R7 A 2018-04-03 K. pneumoniae R I S S #> 3 P3 A 2014-09-19 E. coli R S S S #> 4 P10 A 2015-12-10 E. coli S I S S #> 5 B7 A 2015-03-02 E. coli S S S S #> 6 W3 A 2018-03-31 S. aureus R S R S #> 7 J8 A 2016-06-14 E. coli R S S S #> 8 M3 A 2015-10-25 E. coli R S S S #> 9 J3 A 2019-06-19 E. coli S S S S #> 10 G6 A 2015-04-27 S. aureus S S S S #> # ℹ 2,990 more rows # we will use 'our_data' as the data set name for this tutorial our_data <- example_isolates_unclean"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"taxonomy-of-microorganisms","dir":"Articles","previous_headings":"Preparation","what":"Taxonomy of microorganisms","title":"Conduct AMR data analysis","text":".mo(), users can transform arbitrary microorganism names codes current taxonomy. AMR package contains --date taxonomic data. specific, currently included data retrieved 07 May 2026. codes AMR packages come .mo() short, still human readable. importantly, .mo() supports kinds input: first character codes denote taxonomic kingdom, Bacteria (B), Fungi (F), Protozoa (P). AMR package also contain functions directly retrieve taxonomic properties, name, genus, species, family, order, even Gram-stain. start mo_ use .mo() internally, still arbitrary user input can used: Now can thus clean data: Apparently, uncertainty translation taxonomic codes. Let’s check : ’s good.","code":"as.mo(\"Klebsiella pneumoniae\") #> Class #> [1] B_KLBSL_PNMN as.mo(\"K. pneumoniae\") #> Class #> [1] B_KLBSL_PNMN as.mo(\"KLEPNE\") #> Class #> [1] B_KLBSL_PNMN as.mo(\"KLPN\") #> Class #> [1] B_KLBSL_PNMN mo_family(\"K. pneumoniae\") #> [1] \"Enterobacteriaceae\" mo_genus(\"K. pneumoniae\") #> [1] \"Klebsiella\" mo_species(\"K. pneumoniae\") #> [1] \"pneumoniae\" mo_gramstain(\"Klebsiella pneumoniae\") #> [1] \"Gram-negative\" mo_ref(\"K. pneumoniae\") #> [1] \"Trevisan, 1887\" mo_snomed(\"K. pneumoniae\") #> [[1]] #> [1] \"1098101000112102\" \"446870005\" \"1098201000112108\" \"409801009\" #> [5] \"56415008\" \"714315002\" \"713926009\" our_data$bacteria <- as.mo(our_data$bacteria, info = TRUE) #> ℹ Retrieved values from the `microorganisms.codes` data set for \"ESCCOL\", #> \"KLEPNE\", \"STAAUR\", and \"STRPNE\". #> ℹ Microorganism translation was uncertain for four microorganisms. Run #> `mo_uncertainties()` to review these uncertainties, or use #> `add_custom_microorganisms()` to add custom entries. mo_uncertainties() #> Matching scores are based on the resemblance between the input and the full #> taxonomic name, and the pathogenicity in humans. See `mo_matching_score()`. #> Colour keys: 0.000-0.549 0.550-0.649 0.650-0.749 0.750-1.000 #> ------------------------------------------------------------------------------- #> \"E. coli\" -> Escherichia coli (B_ESCHR_COLI, 0.688) #> Also matched: Enterococcus crotali (0.650), Escherichia coli coli (0.643), #> Escherichia coli expressing (0.611), Enterobacter cowanii (0.600), Enterococcus #> columbae (0.595), Enterococcus camelliae (0.591), Enterococcus casseliflavus #> (0.577), Enterobacter cloacae cloacae (0.571), Enterobacter cloacae complex #> (0.571), and Enterobacter cloacae dissolvens (0.565) #> ------------------------------------------------------------------------------- #> \"K. pneumoniae\" -> Klebsiella pneumoniae (B_KLBSL_PNMN, 0.786) #> Also matched: Klebsiella pneumoniae complex (0.707), Klebsiella pneumoniae #> ozaenae (0.707), Klebsiella pneumoniae pneumoniae (0.688), Klebsiella #> pneumoniae rhinoscleromatis (0.658), Klebsiella pasteurii (0.500), Klebsiella #> planticola (0.500), Kosakonia pseudosacchari (0.471), Kaistella palustris #> (0.435), Kingella potus (0.435), and Kocuria palustris (0.435) #> ------------------------------------------------------------------------------- #> \"S. aureus\" -> Staphylococcus aureus (B_STPHY_AURS, 0.690) #> Also matched: Staphylococcus aureus aureus (0.643), Staphylococcus argenteus #> (0.625), Staphylococcus aureus anaerobius (0.625), Streptomyces aureus (0.618), #> Staphylococcus auricularis (0.615), Streptomyces azureus (0.609), Salmonella #> Aurelianis (0.595), Salmonella Aarhus (0.588), Salmonella Amounderness (0.587), #> and Staphylococcus argensis (0.587) #> ------------------------------------------------------------------------------- #> \"S. pneumoniae\" -> Streptococcus pneumoniae (B_STRPT_PNMN, 0.750) #> Also matched: Streptococcus parapneumoniae (0.714), Streptococcus #> pseudopneumoniae (0.700), Serratia proteamaculans quinivorans (0.557), #> Streptococcus phocae salmonis (0.552), Serratia proteamaculans quinovora #> (0.545), Sphingomonas piscinae (0.538), Streptococcus pseudoporcinus (0.536), #> Staphylococcus piscifermentans (0.533), Staphylococcus pseudintermedius #> (0.532), and Serratia proteamaculans proteamaculans (0.526) #> ℹ Only the first 10 other matches of each record are shown. Run `` #> `print(mo_uncertainties(), n = ...)` `` to view more entries, or save #> `mo_uncertainties()` to an object."},{"path":"https://amr-for-r.org/articles/AMR.html","id":"antibiotic-results","dir":"Articles","previous_headings":"Preparation","what":"Antibiotic results","title":"Conduct AMR data analysis","text":"column antibiotic test results must also cleaned. AMR package comes three new data types work test results: mic minimal inhibitory concentrations (MIC), disk disk diffusion diameters, sir SIR data interpreted already. package can also determine SIR values based MIC disk diffusion values, read .sir() page. now, just clean SIR columns data using dplyr: basically cleaning, time start data inclusion.","code":"# method 1, be explicit about the columns: our_data <- our_data %>% mutate_at(vars(AMX:GEN), as.sir) # method 2, let the AMR package determine the eligible columns our_data <- our_data %>% mutate_if(is_sir_eligible, as.sir) # result: our_data #> # A tibble: 3,000 × 8 #> patient_id hospital date bacteria AMX AMC CIP GEN #> #> 1 J3 A 2012-11-21 B_ESCHR_COLI R I S S #> 2 R7 A 2018-04-03 B_KLBSL_PNMN R I S S #> 3 P3 A 2014-09-19 B_ESCHR_COLI R S S S #> 4 P10 A 2015-12-10 B_ESCHR_COLI S I S S #> 5 B7 A 2015-03-02 B_ESCHR_COLI S S S S #> 6 W3 A 2018-03-31 B_STPHY_AURS R S R S #> 7 J8 A 2016-06-14 B_ESCHR_COLI R S S S #> 8 M3 A 2015-10-25 B_ESCHR_COLI R S S S #> 9 J3 A 2019-06-19 B_ESCHR_COLI S S S S #> 10 G6 A 2015-04-27 B_STPHY_AURS S S S S #> # ℹ 2,990 more rows"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"first-isolates","dir":"Articles","previous_headings":"Preparation","what":"First isolates","title":"Conduct AMR data analysis","text":"need know isolates can actually use analysis without repetition bias. conduct analysis antimicrobial resistance, must include first isolate every patient per episode (Hindler et al., Clin Infect Dis. 2007). , easily get overestimate underestimate resistance antibiotic. Imagine patient admitted MRSA found 5 different blood cultures following weeks (yes, countries like Netherlands blood drawing policies). resistance percentage oxacillin isolates overestimated, included MRSA . clearly selection bias. Clinical Laboratory Standards Institute (CLSI) appoints follows: (…) preparing cumulative antibiogram guide clinical decisions empirical antimicrobial therapy initial infections, first isolate given species per patient, per analysis period (eg, one year) included, irrespective body site, antimicrobial susceptibility profile, phenotypical characteristics (eg, biotype). first isolate easily identified, cumulative antimicrobial susceptibility test data prepared using first isolate generally comparable cumulative antimicrobial susceptibility test data calculated methods, providing duplicate isolates excluded. M39-A4 Analysis Presentation Cumulative Antimicrobial Susceptibility Test Data, 4th Edition. CLSI, 2014. Chapter 6.4 AMR package includes methodology first_isolate() function able apply four different methods defined Hindler et al. 2007: phenotype-based, episode-based, patient-based, isolate-based. right method depends goals analysis, default phenotype-based method case method properly correct duplicate isolates. Read methods first_isolate() page. outcome function can easily added data: 91% suitable resistance analysis! can now filter filter() function, also dplyr package: future use, two syntaxes can shortened: end 2 724 isolates analysis. Now data looks like: Time analysis.","code":"our_data <- our_data %>% mutate(first = first_isolate(info = TRUE)) #> ℹ Determining first isolates using an episode length of 365 days #> ℹ Using column bacteria as input for `col_mo`. #> ℹ Column first is SIR eligible (despite only having empty values), since it #> seems to be cefozopran (ZOP) #> ℹ Using column date as input for `col_date`. #> ℹ Using column patient_id as input for `col_patient_id`. #> ℹ Basing inclusion on all antimicrobial results, using a points threshold of 2 #> => Found 2,724 'phenotype-based' first isolates (90.8% of total where a #> microbial ID was available) our_data_1st <- our_data %>% filter(first == TRUE) our_data_1st <- our_data %>% filter_first_isolate() our_data_1st #> # A tibble: 2,724 × 9 #> patient_id hospital date bacteria AMX AMC CIP GEN first #> #> 1 J3 A 2012-11-21 B_ESCHR_COLI R I S S TRUE #> 2 R7 A 2018-04-03 B_KLBSL_PNMN R I S S TRUE #> 3 P3 A 2014-09-19 B_ESCHR_COLI R S S S TRUE #> 4 P10 A 2015-12-10 B_ESCHR_COLI S I S S TRUE #> 5 B7 A 2015-03-02 B_ESCHR_COLI S S S S TRUE #> 6 W3 A 2018-03-31 B_STPHY_AURS R S R S TRUE #> 7 M3 A 2015-10-25 B_ESCHR_COLI R S S S TRUE #> 8 J3 A 2019-06-19 B_ESCHR_COLI S S S S TRUE #> 9 G6 A 2015-04-27 B_STPHY_AURS S S S S TRUE #> 10 P4 A 2011-06-21 B_ESCHR_COLI S S S S TRUE #> # ℹ 2,714 more rows"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"analysing-the-data","dir":"Articles","previous_headings":"","what":"Analysing the data","title":"Conduct AMR data analysis","text":"base R summary() function gives good first impression, comes support new mo sir classes now data set:","code":"summary(our_data_1st) #> patient_id hospital date bacteria #> Length :2724 Length :2724 Min. :2011-01-01 Class :mo #> N.unique : 260 N.unique : 3 1st Qu.:2013-04-07 :0 #> N.blank : 0 N.blank : 0 Median :2015-06-03 Unique:4 #> Min.nchar: 2 Min.nchar: 1 Mean :2015-06-09 #1 :B_ESCHR_COLI #> Max.nchar: 3 Max.nchar: 1 3rd Qu.:2017-08-11 #2 :B_STPHY_AURS #> Max. :2019-12-27 #3 :B_STRPT_PNMN #> AMX AMC CIP #> Class:sir Class:sir Class:sir #> %S :41.6% (n=1133) %S :52.6% (n=1432) %S :52.5% (n=1431) #> %SDD : 0.0% (n=0) %SDD : 0.0% (n=0) %SDD : 0.0% (n=0) #> %I :16.4% (n=446) %I :12.2% (n=333) %I : 6.5% (n=176) #> %R :42.0% (n=1145) %R :35.2% (n=959) %R :41.0% (n=1117) #> %NI : 0.0% (n=0) %NI : 0.0% (n=0) %NI : 0.0% (n=0) #> GEN first #> Class:sir Mode:logical #> %S :61.0% (n=1661) TRUE:2724 #> %SDD : 0.0% (n=0) #> %I : 3.0% (n=82) #> %R :36.0% (n=981) #> %NI : 0.0% (n=0) glimpse(our_data_1st) #> Rows: 2,724 #> Columns: 9 #> $ patient_id \"J3\", \"R7\", \"P3\", \"P10\", \"B7\", \"W3\", \"M3\", \"J3\", \"G6\", \"P4\"… #> $ hospital \"A\", \"A\", \"A\", \"A\", \"A\", \"A\", \"A\", \"A\", \"A\", \"A\", \"A\", \"A\",… #> $ date 2012-11-21, 2018-04-03, 2014-09-19, 2015-12-10, 2015-03-02… #> $ bacteria \"B_ESCHR_COLI\", \"B_KLBSL_PNMN\", \"B_ESCHR_COLI\", \"B_ESCHR_COL… #> $ AMX R, R, R, S, S, R, R, S, S, S, S, R, S, S, R, R, R, R, S, R,… #> $ AMC I, I, S, I, S, S, S, S, S, S, S, S, S, S, S, S, S, R, S, S,… #> $ CIP S, S, S, S, S, R, S, S, S, S, S, S, S, S, S, S, S, S, S, S,… #> $ GEN S, S, S, S, S, S, S, S, S, S, S, R, S, S, S, S, S, S, S, S,… #> $ first TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE, TRUE,… # number of unique values per column: sapply(our_data_1st, n_distinct) #> patient_id hospital date bacteria AMX AMC CIP #> 260 3 1854 4 3 3 3 #> GEN first #> 3 1"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"availability-of-species","dir":"Articles","previous_headings":"Analysing the data","what":"Availability of species","title":"Conduct AMR data analysis","text":"just get idea species distributed, create frequency table count() based name microorganisms:","code":"our_data %>% count(mo_name(bacteria), sort = TRUE) #> # A tibble: 4 × 2 #> `mo_name(bacteria)` n #> #> 1 Escherichia coli 1518 #> 2 Staphylococcus aureus 730 #> 3 Streptococcus pneumoniae 426 #> 4 Klebsiella pneumoniae 326 our_data_1st %>% count(mo_name(bacteria), sort = TRUE) #> # A tibble: 4 × 2 #> `mo_name(bacteria)` n #> #> 1 Escherichia coli 1321 #> 2 Staphylococcus aureus 682 #> 3 Streptococcus pneumoniae 402 #> 4 Klebsiella pneumoniae 319"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"select-and-filter-with-antimicrobial-selectors","dir":"Articles","previous_headings":"Analysing the data","what":"Select and filter with antimicrobial selectors","title":"Conduct AMR data analysis","text":"Using -called antimicrobial class selectors, can select filter columns based antimicrobial class antimicrobial results :","code":"our_data_1st %>% select(date, aminoglycosides()) #> ℹ For `aminoglycosides()` using column GEN #> (gentamicin) #> # A tibble: 2,724 × 2 #> date GEN #> #> 1 2012-11-21 S #> 2 2018-04-03 S #> 3 2014-09-19 S #> 4 2015-12-10 S #> 5 2015-03-02 S #> 6 2018-03-31 S #> 7 2015-10-25 S #> 8 2019-06-19 S #> 9 2015-04-27 S #> 10 2011-06-21 S #> # ℹ 2,714 more rows our_data_1st %>% select(bacteria, betalactams()) #> ℹ For `betalactams()` using columns AMX (amoxicillin) and AMC #> (amoxicillin/clavulanic acid) #> # A tibble: 2,724 × 3 #> bacteria AMX AMC #> #> 1 B_ESCHR_COLI R I #> 2 B_KLBSL_PNMN R I #> 3 B_ESCHR_COLI R S #> 4 B_ESCHR_COLI S I #> 5 B_ESCHR_COLI S S #> 6 B_STPHY_AURS R S #> 7 B_ESCHR_COLI R S #> 8 B_ESCHR_COLI S S #> 9 B_STPHY_AURS S S #> 10 B_ESCHR_COLI S S #> # ℹ 2,714 more rows our_data_1st %>% select(bacteria, where(is.sir)) #> # A tibble: 2,724 × 5 #> bacteria AMX AMC CIP GEN #> #> 1 B_ESCHR_COLI R I S S #> 2 B_KLBSL_PNMN R I S S #> 3 B_ESCHR_COLI R S S S #> 4 B_ESCHR_COLI S I S S #> 5 B_ESCHR_COLI S S S S #> 6 B_STPHY_AURS R S R S #> 7 B_ESCHR_COLI R S S S #> 8 B_ESCHR_COLI S S S S #> 9 B_STPHY_AURS S S S S #> 10 B_ESCHR_COLI S S S S #> # ℹ 2,714 more rows # filtering using antimicrobial selectors is also possible: our_data_1st %>% filter(any(aminoglycosides() == \"R\")) #> ℹ For `aminoglycosides()` using column GEN #> (gentamicin) #> # A tibble: 981 × 9 #> patient_id hospital date bacteria AMX AMC CIP GEN first #> #> 1 J5 A 2017-12-25 B_STRPT_PNMN R S S R TRUE #> 2 X1 A 2017-07-04 B_STPHY_AURS R S S R TRUE #> 3 B3 A 2016-07-24 B_ESCHR_COLI S S S R TRUE #> 4 V7 A 2012-04-03 B_ESCHR_COLI S S S R TRUE #> 5 C9 A 2017-03-23 B_ESCHR_COLI S S S R TRUE #> 6 R1 A 2018-06-10 B_STPHY_AURS S S S R TRUE #> 7 S2 A 2013-07-19 B_STRPT_PNMN S S S R TRUE #> 8 P5 A 2019-03-09 B_STPHY_AURS S S S R TRUE #> 9 Q8 A 2019-08-10 B_STPHY_AURS S S S R TRUE #> 10 K5 A 2013-03-15 B_STRPT_PNMN S S S R TRUE #> # ℹ 971 more rows our_data_1st %>% filter(all(betalactams() == \"R\")) #> ℹ For `betalactams()` using columns AMX (amoxicillin) and AMC #> (amoxicillin/clavulanic acid) #> # A tibble: 462 × 9 #> patient_id hospital date bacteria AMX AMC CIP GEN first #> #> 1 M7 A 2013-07-22 B_STRPT_PNMN R R S S TRUE #> 2 R10 A 2013-12-20 B_STPHY_AURS R R S S TRUE #> 3 R7 A 2015-10-25 B_STPHY_AURS R R S S TRUE #> 4 R8 A 2019-10-25 B_STPHY_AURS R R S S TRUE #> 5 B6 A 2016-11-20 B_ESCHR_COLI R R R R TRUE #> 6 I7 A 2015-08-19 B_ESCHR_COLI R R S S TRUE #> 7 N3 A 2014-12-29 B_STRPT_PNMN R R R S TRUE #> 8 Q2 A 2019-09-22 B_ESCHR_COLI R R S S TRUE #> 9 X7 A 2011-03-20 B_ESCHR_COLI R R S R TRUE #> 10 V1 A 2018-08-07 B_STPHY_AURS R R S S TRUE #> # ℹ 452 more rows # even works in base R (since R 3.0): our_data_1st[all(betalactams() == \"R\"), ] #> ℹ For `betalactams()` using columns AMX (amoxicillin) and AMC #> (amoxicillin/clavulanic acid) #> # A tibble: 462 × 9 #> patient_id hospital date bacteria AMX AMC CIP GEN first #> #> 1 M7 A 2013-07-22 B_STRPT_PNMN R R S S TRUE #> 2 R10 A 2013-12-20 B_STPHY_AURS R R S S TRUE #> 3 R7 A 2015-10-25 B_STPHY_AURS R R S S TRUE #> 4 R8 A 2019-10-25 B_STPHY_AURS R R S S TRUE #> 5 B6 A 2016-11-20 B_ESCHR_COLI R R R R TRUE #> 6 I7 A 2015-08-19 B_ESCHR_COLI R R S S TRUE #> 7 N3 A 2014-12-29 B_STRPT_PNMN R R R S TRUE #> 8 Q2 A 2019-09-22 B_ESCHR_COLI R R S S TRUE #> 9 X7 A 2011-03-20 B_ESCHR_COLI R R S R TRUE #> 10 V1 A 2018-08-07 B_STPHY_AURS R R S S TRUE #> # ℹ 452 more rows"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"generate-antibiograms","dir":"Articles","previous_headings":"Analysing the data","what":"Generate antibiograms","title":"Conduct AMR data analysis","text":"AMR package supports 28 different languages antibiograms provides four types, proposed Klinker et al. (2021, DOI 10.1177/20499361211011373): Traditional Antibiogram (TA) – susceptibility species individual antibiotics Combination Antibiogram (CA) – susceptibility species combination regimens Syndromic Antibiogram (SA) – susceptibility species, stratified clinical syndrome setting Weighted-Incidence Syndromic Combination Antibiogram (WISCA) – estimated empirical coverage regimen syndrome, weighted pathogen incidence quantified uncertainty goal guide empirical therapy, WISCA default. reason simple: start empirical treatment, know pathogen causing infection. next patient present species label attached . matters probability regimen choose cover whatever pathogen turns cause, given local epidemiology syndrome. Traditional antibiograms answer question. fragment information species, ignore frequently species causes syndrome, evaluate combination regimens, provide measure uncertainty. WISCA addresses limitations using Bayesian framework (Hebert et al., 2012; Bielicki et al., 2016). See WISCA vignette full explanation. Traditional, combination, syndromic antibiograms remain useful surveillance purposes, .e., tracking resistance trends per species time. care clinical impact, choosing right empirical regimen patient, use WISCA. starters, included example_isolates data set looks like:","code":"example_isolates #> # A tibble: 2,000 × 46 #> date patient age gender ward mo PEN OXA FLC AMX #> #> 1 2002-01-02 A77334 65 F Clinical B_ESCHR_COLI R NA NA NA #> 2 2002-01-03 A77334 65 F Clinical B_ESCHR_COLI R NA NA NA #> 3 2002-01-07 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 4 2002-01-07 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 5 2002-01-13 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 6 2002-01-13 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 7 2002-01-14 462729 78 M Clinical B_STPHY_AURS R NA S R #> 8 2002-01-14 462729 78 M Clinical B_STPHY_AURS R NA S R #> 9 2002-01-16 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 10 2002-01-17 858515 79 F ICU B_STPHY_EPDR R NA S NA #> # ℹ 1,990 more rows #> # ℹ 36 more variables: AMC , AMP , TZP , CZO , FEP , #> # CXM , FOX , CTX , CAZ , CRO , GEN , #> # TOB , AMK , KAN , TMP , SXT , NIT , #> # FOS , LNZ , CIP , MFX , VAN , TEC , #> # TCY , TGC , DOX , ERY , CLI , AZM , #> # IPM , MEM , MTR , CHL , COL , MUP , …"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"wisca-recommended-for-empirical-therapy-guidance","dir":"Articles","previous_headings":"Analysing the data > Generate antibiograms","what":"WISCA (recommended for empirical therapy guidance)","title":"Conduct AMR data analysis","text":"Use wisca() function, equivalently antibiogram(..., wisca = TRUE). WISCA produces single coverage estimate per regimen entire syndrome, weighted pathogen incidence, 95% credible interval Bayesian Monte Carlo simulation: output tells : “given species distribution data, estimated X% probability regimen covers infection, 95% credible interval [lower, upper]”. clinically relevant question. syndrome-specific patient-specific WISCA, use syndromic_group argument group data first. can stratify anything: ward, age group, risk profile, acquisition type. syndromic_group argument accepts column expression: Keep mind granular stratification produces relevant estimates subgroup, wider credible intervals due smaller sample sizes. always trade-granularity precision. local numbers small, consider pooling data multiple sites (Bielicki et al., 2016). reliable WISCA results, ensure data includes first isolates (use first_isolate()) consider filtering top n species (use top_n_microorganisms()), since rare contaminants can distort coverage estimates. creating WISCA model, assessments can done distributions Monte Carlo simulations WISCA carried :","code":"wisca_result <- example_isolates %>% wisca( antimicrobials = c(\"TZP\", \"TZP+TOB\", \"TZP+GEN\"), minimum = 10 ) # Recommended threshold: ≥30 wisca_result wisca_out <- example_isolates %>% top_n_microorganisms(n = 10) %>% group_by( age_group = age_groups(age, c(25, 50, 75)), gender ) %>% wisca(antimicrobials = c(\"TZP\", \"TZP+TOB\", \"TZP+GEN\")) wisca_out wisca_plot(wisca_out) wisca_plot(wisca_out, wisca_plot_type = \"posterior_coverage\") # a ggplot2 extension for WISCAs and other antibiograms: ggplot2::autoplot(wisca_out)"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"traditional-antibiogram","dir":"Articles","previous_headings":"Analysing the data > Generate antibiograms","what":"Traditional Antibiogram","title":"Conduct AMR data analysis","text":"need per-species susceptibility rates, e.g., AMR surveillance reports, traditional antibiogram remains right tool. reports proportion susceptible isolates per species per antibiotic: Notice antibiogram() function automatically prints right format using Quarto R Markdown (page), even applies italics taxonomic names (using italicise_taxonomy() internally). also uses language OS either English, Arabic, Bengali, Chinese, Czech, Danish, Dutch, Finnish, French, German, Greek, Hindi, Indonesian, Italian, Japanese, Korean, Norwegian, Polish, Portuguese, Romanian, Russian, Spanish, Swahili, Swedish, Turkish, Ukrainian, Urdu, Vietnamese. next example, force language Spanish using language argument:","code":"antibiogram(example_isolates, antibiotics = c(aminoglycosides(), carbapenems()) ) #> ℹ For `aminoglycosides()` using columns GEN (gentamicin), TOB (tobramycin), AMK #> (amikacin), and KAN (kanamycin) #> ℹ For `carbapenems()` using columns IPM (imipenem) and MEM (meropenem) antibiogram(example_isolates, mo_transform = \"gramstain\", antibiotics = aminoglycosides(), ab_transform = \"name\", language = \"es\" ) #> ℹ For `aminoglycosides()` using columns GEN (gentamicin), TOB (tobramycin), AMK #> (amikacin), and KAN (kanamycin)"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"combination-antibiogram","dir":"Articles","previous_headings":"Analysing the data > Generate antibiograms","what":"Combination Antibiogram","title":"Conduct AMR data analysis","text":"combination antibiogram shows much additional susceptibility second agent adds given species. useful surveillance combination regimens, note still species-stratified account pathogen incidence syndrome:","code":"combined_ab <- antibiogram(example_isolates, antibiotics = c(\"TZP\", \"TZP+TOB\", \"TZP+GEN\"), ab_transform = NULL ) combined_ab"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"syndromic-antibiogram","dir":"Articles","previous_headings":"Analysing the data > Generate antibiograms","what":"Syndromic Antibiogram","title":"Conduct AMR data analysis","text":"syndromic antibiogram stratifies per-species susceptibility clinical context (ward, specimen type, etc.). adds clinical context traditional antibiogram still species-level, without incidence weighting uncertainty quantification. surveillance setting fine; empirical therapy guidance, WISCA preferred:","code":"antibiogram(example_isolates, antibiotics = c(aminoglycosides(), carbapenems()), syndromic_group = \"ward\" ) #> ℹ For `aminoglycosides()` using columns GEN (gentamicin), TOB (tobramycin), AMK #> (amikacin), and KAN (kanamycin) #> ℹ For `carbapenems()` using columns IPM (imipenem) and MEM (meropenem)"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"plotting-antibiograms","dir":"Articles","previous_headings":"Analysing the data > Generate antibiograms","what":"Plotting antibiograms","title":"Conduct AMR data analysis","text":"antibiogram types, including WISCA, can plotted using autoplot() ggplot2 package, since AMR package provides extension function: calculate antimicrobial resistance sensible way, also correcting results, use resistance() susceptibility() functions.","code":"autoplot(wisca_result)"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"resistance-percentages","dir":"Articles","previous_headings":"Analysing the data","what":"Resistance percentages","title":"Conduct AMR data analysis","text":"functions resistance() susceptibility() can used calculate antimicrobial resistance susceptibility. specific analyses, functions proportion_S(), proportion_SI(), proportion_I(), proportion_IR() proportion_R() can used determine proportion specific antimicrobial outcome. functions contain minimum argument, denoting minimum required number test results returning value. functions otherwise return NA. default minimum = 30, following CLSI M39-A4 guideline applying microbial epidemiology. per EUCAST guideline 2019, calculate resistance proportion R (proportion_R(), equal resistance()) susceptibility proportion S (proportion_SI(), equal susceptibility()). functions can used : can used conjunction group_by() summarise(), dplyr package:","code":"our_data_1st %>% resistance(AMX) #> [1] 0.4203377 our_data_1st %>% group_by(hospital) %>% summarise(amoxicillin = resistance(AMX)) #> # A tibble: 3 × 2 #> hospital amoxicillin #> #> 1 A 0.340 #> 2 B 0.551 #> 3 C 0.370"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"interpreting-mic-and-disk-diffusion-values","dir":"Articles","previous_headings":"Analysing the data","what":"Interpreting MIC and Disk Diffusion Values","title":"Conduct AMR data analysis","text":"Minimal inhibitory concentration (MIC) values disk diffusion diameters can interpreted clinical breakpoints (SIR) using .sir(). ’s example randomly generated MIC values Klebsiella pneumoniae ciprofloxacin: allows direct interpretation according EUCAST CLSI breakpoints, facilitating automated AMR data processing.","code":"set.seed(123) mic_values <- random_mic(100) sir_values <- as.sir(mic_values, mo = \"K. pneumoniae\", ab = \"cipro\", guideline = \"EUCAST 2024\") my_data <- tibble(MIC = mic_values, SIR = sir_values) my_data #> # A tibble: 100 × 2 #> MIC SIR #> #> 1 <=0.0001 S #> 2 0.0160 S #> 3 >=8.0000 R #> 4 0.0320 S #> 5 0.0080 S #> 6 64.0000 R #> 7 0.0080 S #> 8 0.1250 S #> 9 0.0320 S #> 10 0.0002 S #> # ℹ 90 more rows"},{"path":"https://amr-for-r.org/articles/AMR.html","id":"plotting-mic-and-sir-interpretations","dir":"Articles","previous_headings":"Analysing the data","what":"Plotting MIC and SIR Interpretations","title":"Conduct AMR data analysis","text":"can visualise MIC distributions SIR interpretations using ggplot2, using new scale_y_mic() y-axis scale_colour_sir() colour-code SIR categories. plot provides intuitive way assess susceptibility patterns across different groups incorporating clinical breakpoints. straightforward less manual approach, ggplot2’s function autoplot() extended package directly plot MIC disk diffusion values: Author: Dr. Matthijs Berends, 23rd June 2026","code":"# add a group my_data$group <- rep(c(\"A\", \"B\", \"C\", \"D\"), each = 25) ggplot( my_data, aes(x = group, y = MIC, colour = SIR) ) + geom_jitter(width = 0.2, size = 2) + geom_boxplot(fill = NA, colour = \"grey40\") + scale_y_mic() + scale_colour_sir() + labs( title = \"MIC Distribution and SIR Interpretation\", x = \"Sample Groups\", y = \"MIC (mg/L)\" ) autoplot(mic_values) # by providing `mo` and `ab`, colours will indicate the SIR interpretation: autoplot(mic_values, mo = \"K. pneumoniae\", ab = \"cipro\", guideline = \"EUCAST 2024\")"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"introduction","dir":"Articles","previous_headings":"","what":"Introduction","title":"AMR for Python","text":"AMR package R powerful tool antimicrobial resistance (AMR) analysis. provides extensive features handling microbial antimicrobial data. However, work primarily Python, now intuitive option available: AMR Python package. Python package wrapper around AMR R package. uses rpy2 package internally. Despite need R installed, Python users can now easily work AMR data directly Python code.","code":""},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"prerequisites","dir":"Articles","previous_headings":"","what":"Prerequisites","title":"AMR for Python","text":"package tested virtual environment (venv). can set environment running: can activate environment, venv ready work .","code":"# linux and macOS: python -m venv /path/to/new/virtual/environment # Windows: python -m venv C:\\path\\to\\new\\virtual\\environment"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"install-amr","dir":"Articles","previous_headings":"","what":"Install AMR","title":"AMR for Python","text":"Since Python package available official Python Package Index, can just run: Make sure R installed. need install AMR R package, installed automatically. Linux: macOS (using Homebrew): Windows, visit CRAN download page download install R.","code":"pip install AMR # Ubuntu / Debian sudo apt install r-base # Fedora: sudo dnf install R # CentOS/RHEL sudo yum install R brew install r"},{"path":[]},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"cleaning-taxonomy","dir":"Articles","previous_headings":"Examples of Usage","what":"Cleaning Taxonomy","title":"AMR for Python","text":"’s example demonstrates clean microorganism drug names using AMR Python package:","code":"import pandas as pd import AMR # Sample data data = { \"MOs\": ['E. coli', 'ESCCOL', 'esco', 'Esche coli'], \"Drug\": ['Cipro', 'CIP', 'J01MA02', 'Ciproxin'] } df = pd.DataFrame(data) # Use AMR functions to clean microorganism and drug names df['MO_clean'] = AMR.mo_name(df['MOs']) df['Drug_clean'] = AMR.ab_name(df['Drug']) # Display the results print(df)"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"explanation","dir":"Articles","previous_headings":"Examples of Usage > Cleaning Taxonomy","what":"Explanation","title":"AMR for Python","text":"mo_name: function standardises microorganism names. , different variations Escherichia coli (“E. coli”, “ESCCOL”, “esco”, “Esche coli”) converted correct, standardised form, “Escherichia coli”. ab_name: Similarly, function standardises antimicrobial names. different representations ciprofloxacin (e.g., “Cipro”, “CIP”, “J01MA02”, “Ciproxin”) converted standard name, “Ciprofloxacin”.","code":""},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"calculating-amr","dir":"Articles","previous_headings":"Examples of Usage","what":"Calculating AMR","title":"AMR for Python","text":"","code":"import AMR import pandas as pd df = AMR.example_isolates result = AMR.resistance(df[\"AMX\"]) print(result) [0.59555556]"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"generating-antibiograms","dir":"Articles","previous_headings":"Examples of Usage","what":"Generating Antibiograms","title":"AMR for Python","text":"One core functions AMR package generating antibiogram, table summarises antimicrobial susceptibility bacterial isolates. ’s can generate antibiogram Python: example, generate antibiogram selecting various antibiotics.","code":"result2a = AMR.antibiogram(df[[\"mo\", \"AMX\", \"CIP\", \"TZP\"]]) print(result2a) result2b = AMR.antibiogram(df[[\"mo\", \"AMX\", \"CIP\", \"TZP\"]], mo_transform = \"gramstain\") print(result2b)"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"taxonomic-data-sets-now-in-python","dir":"Articles","previous_headings":"Examples of Usage","what":"Taxonomic Data Sets Now in Python!","title":"AMR for Python","text":"Python user, might like important data sets AMR R package, microorganisms, antimicrobials, clinical_breakpoints, example_isolates, now available regular Python data frames:","code":"AMR.microorganisms AMR.antimicrobials"},{"path":[]},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"stable-release-cran","dir":"Articles","previous_headings":"Installation Channels","what":"Stable Release (CRAN)","title":"AMR for Python","text":"default AMR Python package uses latest stable version AMR R package, published CRAN. running pip install AMR, import usual:","code":"import AMR AMR.example_isolates"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"development-version-github","dir":"Articles","previous_headings":"Installation Channels","what":"Development Version (GitHub)","title":"AMR for Python","text":"use latest development version AMR R package (sourced directly GitHub), import beta sub-package alias AMR: Aliasing AMR keeps downstream code identical stable import. Switching stable release development version requires changing import line — nothing else script needs change.","code":"import AMR.beta as AMR AMR.example_isolates"},{"path":[]},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"using-enforce_method","dir":"Articles","previous_headings":"SIR Classification with as_sir()","what":"Using enforce_method","title":"AMR for Python","text":"as_sir() function R uses S3 method dispatch select correct calculation method based input class: MIC values disk diffusion values. Python objects carry R class attributes rpy2 bridge, automatic dispatch may resolve correctly. explicitly specify input type, use enforce_method argument: Without enforce_method, R falls back class-based dispatch raw Python input, may fail return unexpected results. Always supply enforce_method calling as_sir() Python.","code":"# Treat the column as MIC values — maps to R's as.sir.mic() AMR.as_sir(df[\"MIC_col\"], mo=\"E. coli\", ab=\"AMX\", guideline=\"EUCAST\", enforce_method=\"mic\") # Treat the column as disk diffusion values — maps to R's as.sir.disk() AMR.as_sir(df[\"disk_col\"], mo=\"E. coli\", ab=\"AMX\", guideline=\"EUCAST\", enforce_method=\"disk\")"},{"path":"https://amr-for-r.org/articles/AMR_for_Python.html","id":"conclusion","dir":"Articles","previous_headings":"","what":"Conclusion","title":"AMR for Python","text":"AMR Python package, Python users can now effortlessly call R functions AMR R package. eliminates need complex rpy2 configurations provides clean, easy--use interface antimicrobial resistance analysis. examples provided demonstrate can applied typical workflows, standardising microorganism antimicrobial names calculating resistance. just running import AMR, users can seamlessly integrate robust features R AMR package Python workflows. Whether ’re cleaning data analysing resistance patterns, AMR Python package makes easy work AMR data Python.","code":""},{"path":"https://amr-for-r.org/articles/AMR_with_tidymodels.html","id":"example-1-using-antimicrobial-selectors","dir":"Articles","previous_headings":"","what":"Example 1: Using Antimicrobial Selectors","title":"AMR with tidymodels","text":"leveraging power tidymodels AMR package, ’ll build reproducible machine learning workflow predict Gramstain microorganism two important antibiotic classes: aminoglycosides beta-lactams.","code":""},{"path":"https://amr-for-r.org/articles/AMR_with_tidymodels.html","id":"objective","dir":"Articles","previous_headings":"Example 1: Using Antimicrobial Selectors","what":"Objective","title":"AMR with tidymodels","text":"goal build predictive model using tidymodels framework determine Gramstain microorganism based microbial data. : Preprocess data using selector functions aminoglycosides() betalactams(). Define logistic regression model prediction. Use structured tidymodels workflow preprocess, train, evaluate model.","code":""},{"path":"https://amr-for-r.org/articles/AMR_with_tidymodels.html","id":"data-preparation","dir":"Articles","previous_headings":"Example 1: Using Antimicrobial Selectors","what":"Data Preparation","title":"AMR with tidymodels","text":"begin loading required libraries preparing example_isolates dataset AMR package. Prepare data: Explanation: aminoglycosides() betalactams() dynamically select columns antimicrobials classes. drop_na() ensures model receives complete cases training.","code":"# Load required libraries library(AMR) # For AMR data analysis library(tidymodels) # For machine learning workflows, and data manipulation (dplyr, tidyr, ...) # Your data could look like this: example_isolates #> # A tibble: 2,000 × 46 #> date patient age gender ward mo PEN OXA FLC AMX #> #> 1 2002-01-02 A77334 65 F Clinical B_ESCHR_COLI R NA NA NA #> 2 2002-01-03 A77334 65 F Clinical B_ESCHR_COLI R NA NA NA #> 3 2002-01-07 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 4 2002-01-07 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 5 2002-01-13 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 6 2002-01-13 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 7 2002-01-14 462729 78 M Clinical B_STPHY_AURS R NA S R #> 8 2002-01-14 462729 78 M Clinical B_STPHY_AURS R NA S R #> 9 2002-01-16 067927 45 F ICU B_STPHY_EPDR R NA R NA #> 10 2002-01-17 858515 79 F ICU B_STPHY_EPDR R NA S NA #> # ℹ 1,990 more rows #> # ℹ 36 more variables: AMC , AMP , TZP , CZO , FEP , #> # CXM , FOX , CTX , CAZ , CRO , GEN , #> # TOB , AMK , KAN , TMP , SXT