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dr. M.S. (Matthijs) Berends
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@ -44,7 +44,7 @@
</button>
<span class="navbar-brand">
<a class="navbar-link" href="../index.html">AMR (for R)</a>
<span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.8.0</span>
<span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Released version">1.8.0.9005</span>
</span>
</div>
@ -185,7 +185,7 @@
</header><div class="row">
</header><script src="MDR_files/accessible-code-block-0.0.1/empty-anchor.js"></script><div class="row">
<div class="col-md-9 contents">
<div class="page-header toc-ignore">
<h1 data-toc-skip>How to determine multi-drug resistance (MDR)</h1>
@ -295,8 +295,8 @@
<span class="co"># Table 3 - Enterobacteriaceae... OK.</span>
<span class="co"># Table 4 - Pseudomonas aeruginosa... OK.</span>
<span class="co"># Table 5 - Acinetobacter spp.... OK.</span>
<span class="co"># Warning: NA introduced for isolates where the available percentage of antimicrobial</span>
<span class="co"># classes was below 50% (set with `pct_required_classes`)</span></code></pre></div>
<span class="co"># Warning: in `mdro()`: NA introduced for isolates where the available percentage of</span>
<span class="co"># antimicrobial classes was below 50% (set with `pct_required_classes`)</span></code></pre></div>
<p>Only results with ‘R’ are considered as resistance. Use <code>combine_SI = FALSE</code> to also consider ‘I’ as resistance.</p>
<p>Determining multidrug-resistant organisms (MDRO), according to: Guideline: Multidrug-resistant, extensively drug-resistant and pandrug-resistant bacteria: an international expert proposal for interim standard definitions for acquired resistance. Author(s): Magiorakos AP, Srinivasan A, Carey RB, …, Vatopoulos A, Weber JT, Monnet DL Source: Clinical Microbiology and Infection 18:3, 2012; doi: 10.1111/j.1469-0691.2011.03570.x</p>
<p>(16 isolates had no test results)</p>
@ -320,17 +320,17 @@ Unique: 2</p>
<td align="left">1</td>
<td align="left">Negative</td>
<td align="right">1601</td>
<td align="right">92.60%</td>
<td align="right">92.6%</td>
<td align="right">1601</td>
<td align="right">92.60%</td>
<td align="right">92.6%</td>
</tr>
<tr class="even">
<td align="left">2</td>
<td align="left">Multi-drug-resistant (MDR)</td>
<td align="right">128</td>
<td align="right">7.40%</td>
<td align="right">7.4%</td>
<td align="right">1729</td>
<td align="right">100.00%</td>
<td align="right">100.0%</td>
</tr>
</tbody>
</table>
@ -358,18 +358,18 @@ Unique: 2</p>
<div class="sourceCode" id="cb8"><pre class="downlit sourceCode r">
<code class="sourceCode R"><span class="fu"><a href="https://rdrr.io/r/utils/head.html" class="external-link">head</a></span><span class="op">(</span><span class="va">my_TB_data</span><span class="op">)</span>
<span class="co"># rifampicin isoniazid gatifloxacin ethambutol pyrazinamide moxifloxacin</span>
<span class="co"># 1 I R I S R S</span>
<span class="co"># 2 I S R R S R</span>
<span class="co"># 3 R I S I R S</span>
<span class="co"># 4 S S I R I S</span>
<span class="co"># 5 S R S S S I</span>
<span class="co"># 6 S R R S R I</span>
<span class="co"># 1 I R I R I I</span>
<span class="co"># 2 I R I I I I</span>
<span class="co"># 3 S I I R S S</span>
<span class="co"># 4 R I R I R I</span>
<span class="co"># 5 S I S S R S</span>
<span class="co"># 6 S S I I I S</span>
<span class="co"># kanamycin</span>
<span class="co"># 1 S</span>
<span class="co"># 2 I</span>
<span class="co"># 3 R</span>
<span class="co"># 4 R</span>
<span class="co"># 5 I</span>
<span class="co"># 1 I</span>
<span class="co"># 2 R</span>
<span class="co"># 3 I</span>
<span class="co"># 4 I</span>
<span class="co"># 5 R</span>
<span class="co"># 6 R</span></code></pre></div>
<p>We can now add the interpretation of MDR-TB to our data set. You can use:</p>
<div class="sourceCode" id="cb9"><pre class="downlit sourceCode r">
@ -398,7 +398,7 @@ Unique: 2</p>
<p>Class: factor &gt; ordered (numeric)<br>
Length: 5,000<br>
Levels: 5: Negative &lt; Mono-resistant &lt; Poly-resistant &lt; Multi-drug-resistant &lt;…<br>
Available: 5,000 (100.0%, NA: 0 = 0.0%)<br>
Available: 5,000 (100%, NA: 0 = 0%)<br>
Unique: 5</p>
<table class="table">
<thead><tr class="header">
@ -413,40 +413,40 @@ Unique: 5</p>
<tr class="odd">
<td align="left">1</td>
<td align="left">Mono-resistant</td>
<td align="right">3250</td>
<td align="right">65.00%</td>
<td align="right">3250</td>
<td align="right">65.00%</td>
<td align="right">3243</td>
<td align="right">64.86%</td>
<td align="right">3243</td>
<td align="right">64.86%</td>
</tr>
<tr class="even">
<td align="left">2</td>
<td align="left">Negative</td>
<td align="right">975</td>
<td align="right">19.50%</td>
<td align="right">4225</td>
<td align="right">84.50%</td>
<td align="right">969</td>
<td align="right">19.38%</td>
<td align="right">4212</td>
<td align="right">84.24%</td>
</tr>
<tr class="odd">
<td align="left">3</td>
<td align="left">Multi-drug-resistant</td>
<td align="right">474</td>
<td align="right">9.48%</td>
<td align="right">4699</td>
<td align="right">93.98%</td>
<td align="right">425</td>
<td align="right">8.50%</td>
<td align="right">4637</td>
<td align="right">92.74%</td>
</tr>
<tr class="even">
<td align="left">4</td>
<td align="left">Poly-resistant</td>
<td align="right">203</td>
<td align="right">4.06%</td>
<td align="right">4902</td>
<td align="right">98.04%</td>
<td align="right">263</td>
<td align="right">5.26%</td>
<td align="right">4900</td>
<td align="right">98.00%</td>
</tr>
<tr class="odd">
<td align="left">5</td>
<td align="left">Extensively drug-resistant</td>
<td align="right">98</td>
<td align="right">1.96%</td>
<td align="right">100</td>
<td align="right">2.00%</td>
<td align="right">5000</td>
<td align="right">100.00%</td>
</tr>
@ -470,7 +470,7 @@ Unique: 5</p>
<div class="pkgdown">
<p></p>
<p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.0.</p>
<p>Site built with <a href="https://pkgdown.r-lib.org/" class="external-link">pkgdown</a> 2.0.2.</p>
</div>
</footer>