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(v0.7.1.9063) septic_patients -> example_isolates

This commit is contained in:
2019-08-27 16:45:42 +02:00
parent 7a6fce4eb8
commit 93be16484b
92 changed files with 1143 additions and 818 deletions

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@ -461,12 +461,12 @@ data_1st %>%
## Independence test
The next example uses the included `septic_patients`, which is an anonymised data set containing 2,000 microbial blood culture isolates with their full antibiograms found in septic patients in 4 different hospitals in the Netherlands, between 2001 and 2017. It is true, genuine data. This `data.frame` can be used to practice AMR analysis.
The next example uses the included `example_isolates`, which is an anonymised data set containing 2,000 microbial blood culture isolates with their full antibiograms found in septic patients in 4 different hospitals in the Netherlands, between 2001 and 2017. This `data.frame` can be used to practice AMR analysis.
We will compare the resistance to fosfomycin (column `FOS`) in hospital A and D. The input for the `fisher.test()` can be retrieved with a transformation like this:
```{r, results = 'markup'}
check_FOS <- septic_patients %>%
check_FOS <- example_isolates %>%
filter(hospital_id %in% c("A", "D")) %>% # filter on only hospitals A and D
select(hospital_id, FOS) %>% # select the hospitals and fosfomycin
group_by(hospital_id) %>% # group on the hospitals

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@ -114,8 +114,8 @@ Repetitive results are unique values that are present more than once. Unique val
```{r, message = FALSE}
library(dplyr)
# take all MO codes from the septic_patients data set
x <- septic_patients$mo %>%
# take all MO codes from the example_isolates data set
x <- example_isolates$mo %>%
# keep only the unique ones
unique() %>%
# pick 50 of them at random

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@ -42,15 +42,15 @@ Our package contains a function `resistance_predict()`, which takes the same inp
It is basically as easy as:
```{r, eval = FALSE}
# resistance prediction of piperacillin/tazobactam (TZP):
resistance_predict(tbl = septic_patients, col_date = "date", col_ab = "TZP", model = "binomial")
resistance_predict(tbl = example_isolates, col_date = "date", col_ab = "TZP", model = "binomial")
# or:
septic_patients %>%
example_isolates %>%
resistance_predict(col_ab = "TZP",
model "binomial")
# to bind it to object 'predict_TZP' for example:
predict_TZP <- septic_patients %>%
predict_TZP <- example_isolates %>%
resistance_predict(col_ab = "TZP",
model = "binomial")
```
@ -60,7 +60,7 @@ The function will look for a date column itself if `col_date` is not set.
When running any of these commands, a summary of the regression model will be printed unless using `resistance_predict(..., info = FALSE)`.
```{r, echo = FALSE}
predict_TZP <- septic_patients %>%
predict_TZP <- example_isolates %>%
resistance_predict(col_ab = "TZP", model = "binomial")
```
@ -92,7 +92,7 @@ ggplot_rsi_predict(predict_TZP, ribbon = FALSE)
Resistance is not easily predicted; if we look at vancomycin resistance in Gram positives, the spread (i.e. standard error) is enormous:
```{r}
septic_patients %>%
example_isolates %>%
filter(mo_gramstain(mo, language = NULL) == "Gram-positive") %>%
resistance_predict(col_ab = "VAN", year_min = 2010, info = FALSE, model = "binomial") %>%
ggplot_rsi_predict()
@ -113,7 +113,7 @@ Valid values are:
For the vancomycin resistance in Gram positive bacteria, a linear model might be more appropriate since no (left half of a) binomial distribution is to be expected based on the observed years:
```{r}
septic_patients %>%
example_isolates %>%
filter(mo_gramstain(mo, language = NULL) == "Gram-positive") %>%
resistance_predict(col_ab = "VAN", year_min = 2010, info = FALSE, model = "linear") %>%
ggplot_rsi_predict()