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Package: AMR
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Package: AMR
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Version: 1.8.2.9133
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Version: 1.8.2.9134
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Date: 2023-02-17
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Date: 2023-02-18
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Title: Antimicrobial Resistance Data Analysis
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Title: Antimicrobial Resistance Data Analysis
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Description: Functions to simplify and standardise antimicrobial resistance (AMR)
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Description: Functions to simplify and standardise antimicrobial resistance (AMR)
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data analysis and to work with microbial and antimicrobial properties by
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data analysis and to work with microbial and antimicrobial properties by
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2
NEWS.md
2
NEWS.md
@ -1,4 +1,4 @@
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# AMR 1.8.2.9133
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# AMR 1.8.2.9134
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*(this beta version will eventually become v2.0! We're happy to reach a new major milestone soon!)*
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*(this beta version will eventually become v2.0! We're happy to reach a new major milestone soon!)*
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@ -1139,7 +1139,7 @@ try_colour <- function(..., before, after, collapse = " ") {
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}
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}
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is_dark <- function() {
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is_dark <- function() {
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if (is.null(AMR_env$is_dark_theme)) {
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if (is.null(AMR_env$is_dark_theme)) {
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AMR_env$is_dark_theme <- tryCatch(isTRUE(getExportedValue("getThemeInfo", ns = asNamespace("rstudioapi"))()$dark), error = function(e) FALSE)
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!has_colour() || AMR_env$is_dark_theme <- tryCatch(isTRUE(getExportedValue("getThemeInfo", ns = asNamespace("rstudioapi"))()$dark), error = function(e) FALSE)
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}
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}
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isTRUE(AMR_env$is_dark_theme)
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isTRUE(AMR_env$is_dark_theme)
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}
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}
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@ -477,7 +477,9 @@ antibiogram <- function(x,
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colnames(new_df)[edit_col] <- paste(colnames(new_df)[edit_col], "(N min-max)")
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colnames(new_df)[edit_col] <- paste(colnames(new_df)[edit_col], "(N min-max)")
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}
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}
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structure(as_original_data_class(new_df, class(x), extra_class = "antibiogram"),
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out <- as_original_data_class(new_df, class(x), extra_class = "antibiogram")
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rownames(out) <- NULL
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structure(out,
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long = long,
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long = long,
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combine_SI = combine_SI
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combine_SI = combine_SI
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)
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)
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@ -164,9 +164,9 @@ bug_drug_combinations <- function(x,
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} else {
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} else {
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out <- run_it(x)
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out <- run_it(x)
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}
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}
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rownames(out) <- NULL
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out <- out %pm>% pm_arrange(mo, ab)
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out <- out %pm>% pm_arrange(mo, ab)
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out <- as_original_data_class(out, class(x.bak)) # will remove tibble groups
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out <- as_original_data_class(out, class(x.bak)) # will remove tibble groups
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rownames(out) <- NULL
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structure(out, class = c("bug_drug_combinations", ifelse(data_has_groups, "grouped", character(0)), class(out)))
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structure(out, class = c("bug_drug_combinations", ifelse(data_has_groups, "grouped", character(0)), class(out)))
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}
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}
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2
index.md
2
index.md
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* Integrates with **WHONET**, ATC, **EARS-Net**, PubChem, **LOINC** and **SNOMED CT**
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* Integrates with **WHONET**, ATC, **EARS-Net**, PubChem, **LOINC** and **SNOMED CT**
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* Works on Windows, macOS and Linux with **all versions of R** since R-3.0 and is completely **dependency-free**, highly suitable for places with **limited resources**
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* Works on Windows, macOS and Linux with **all versions of R** since R-3.0 and is completely **dependency-free**, highly suitable for places with **limited resources**
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<div style="display: flex;">
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<div style="display: flex; font-size: 0.8em;">
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<p style="text-align:left; width: 50%;"><small><a href="https://msberends.github.io/AMR/">https://msberends.github.io/AMR</a></small></p>
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<p style="text-align:left; width: 50%;"><small><a href="https://msberends.github.io/AMR/">https://msberends.github.io/AMR</a></small></p>
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<p style="text-align:right; width: 50%;"><small><a href="https://doi.org/10.18637/jss.v104.i03">https://doi.org/10.18637/jss.v104.i03</a></small></p>
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<p style="text-align:right; width: 50%;"><small><a href="https://doi.org/10.18637/jss.v104.i03">https://doi.org/10.18637/jss.v104.i03</a></small></p>
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</div>
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</div>
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@ -36,6 +36,9 @@
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}
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}
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}
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}
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@media (max-width: 575.98px) {
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@media (max-width: 575.98px) {
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footer .pkgdown-footer-left {
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text-align: center;
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}
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footer .pkgdown-footer-right {
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footer .pkgdown-footer-right {
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text-align: center;
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text-align: center;
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}
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}
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---
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---
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title: "How to conduct AMR data analysis"
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title: "How to conduct AMR data analysis"
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author: "Dr. Matthijs Berends"
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date: '`r format(Sys.Date(), "%d %B %Y")`'
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output:
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output:
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rmarkdown::html_vignette:
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rmarkdown::html_vignette:
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toc: true
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toc: true
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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warning = FALSE,
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warning = FALSE,
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collapse = TRUE,
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collapse = TRUE,
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comment = "#",
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comment = "#>",
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fig.width = 7.5,
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fig.width = 7.5,
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fig.height = 5
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fig.height = 5
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)
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)
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@ -586,13 +584,13 @@ autoplot(
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The next example uses the `example_isolates` data set. This is a data set included with this package and contains 2,000 microbial isolates with their full antibiograms. It reflects reality and can be used to practise AMR data analysis.
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The next example uses the `example_isolates` data set. This is a data set included with this package and contains 2,000 microbial isolates with their full antibiograms. It reflects reality and can be used to practise AMR data analysis.
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We will compare the resistance to amoxicillin/clavulanic acid (column `FOS`) between an ICU and other clinical wards. The input for the `fisher.test()` can be retrieved with a transformation like this:
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We will compare the resistance to amoxicillin/clavulanic acid (column `AMC`) between an ICU and other clinical wards. The input for the `fisher.test()` can be retrieved with a transformation like this:
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```{r, results = 'markup'}
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```{r, results = 'markup'}
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# use package 'tidyr' to pivot data:
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# use package 'tidyr' to pivot data:
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library(tidyr)
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library(tidyr)
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check_FOS <- example_isolates %>%
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check_AMC <- example_isolates %>%
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filter(ward %in% c("ICU", "Clinical")) %>% # filter on only these wards
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filter(ward %in% c("ICU", "Clinical")) %>% # filter on only these wards
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select(ward, AMC) %>% # select the wards and amoxi/clav
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select(ward, AMC) %>% # select the wards and amoxi/clav
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group_by(ward) %>% # group on the wards
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group_by(ward) %>% # group on the wards
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@ -604,14 +602,18 @@ check_FOS <- example_isolates %>%
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select(ICU, Clinical) %>% # and only select these columns
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select(ICU, Clinical) %>% # and only select these columns
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as.matrix() # transform to a good old matrix for fisher.test()
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as.matrix() # transform to a good old matrix for fisher.test()
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check_FOS
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check_AMC
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```
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```
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We can apply the test now with:
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We can apply the test now with:
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```{r}
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```{r}
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# do Fisher's Exact Test
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# do Fisher's Exact Test
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fisher.test(check_FOS)
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fisher.test(check_AMC)
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```
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```
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As can be seen, the p value is practically zero (`r format(fisher.test(check_FOS)$p.value, scientific = FALSE)`), which means that the amoxicillin/clavulanic acid resistance found in isolates between patients in ICUs and other clinical wards are really different.
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As can be seen, the p value is practically zero (`r format(fisher.test(check_AMC)$p.value, scientific = FALSE)`), which means that the amoxicillin/clavulanic acid resistance found in isolates between patients in ICUs and other clinical wards are really different.
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----
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*Author: Dr. Matthijs Berends*
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@ -15,7 +15,7 @@ editor_options:
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```{r setup, include = FALSE, results = 'markup'}
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```{r setup, include = FALSE, results = 'markup'}
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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collapse = TRUE,
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collapse = TRUE,
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comment = "#",
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comment = "#>",
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fig.width = 7.5,
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fig.width = 7.5,
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fig.height = 4.5
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fig.height = 4.5
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)
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)
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```{r setup, include = FALSE, results = 'markup'}
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```{r setup, include = FALSE, results = 'markup'}
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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collapse = TRUE,
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collapse = TRUE,
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comment = "#"
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comment = "#>"
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)
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)
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library(AMR)
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library(AMR)
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```
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```
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@ -15,7 +15,7 @@ editor_options:
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```{r setup, include = FALSE, results = 'markup'}
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```{r setup, include = FALSE, results = 'markup'}
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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collapse = TRUE,
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collapse = TRUE,
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comment = "#",
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comment = "#>",
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fig.width = 7.5,
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fig.width = 7.5,
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fig.height = 4.5,
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fig.height = 4.5,
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dpi = 100
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dpi = 100
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```{r setup, include = FALSE, results = 'markup'}
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```{r setup, include = FALSE, results = 'markup'}
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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collapse = TRUE,
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collapse = TRUE,
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comment = "#"
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comment = "#>"
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)
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)
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# set to original language (English)
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# set to original language (English)
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Sys.setlocale(locale = "C")
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Sys.setlocale(locale = "C")
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@ -15,7 +15,7 @@ editor_options:
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```{r setup, include = FALSE, results = 'markup'}
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```{r setup, include = FALSE, results = 'markup'}
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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collapse = TRUE,
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collapse = TRUE,
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comment = "#",
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comment = "#>",
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fig.width = 7.5,
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fig.width = 7.5,
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fig.height = 4.5
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fig.height = 4.5
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)
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)
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@ -14,7 +14,7 @@ editor_options:
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```{r setup, include = FALSE, results = 'markup'}
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```{r setup, include = FALSE, results = 'markup'}
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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collapse = TRUE,
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collapse = TRUE,
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comment = "#",
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comment = "#>",
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fig.width = 7.5,
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fig.width = 7.5,
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fig.height = 4.75
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fig.height = 4.75
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)
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)
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knitr::opts_chunk$set(
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knitr::opts_chunk$set(
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warning = FALSE,
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warning = FALSE,
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collapse = TRUE,
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collapse = TRUE,
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comment = "#",
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comment = "#>",
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fig.width = 7.5,
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fig.width = 7.5,
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fig.height = 5
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fig.height = 5
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)
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)
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