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docs/articles/EUCAST.html
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<script src="../pkgdown.js"></script><link href="../extra.css" rel="stylesheet">
<script src="../extra.js"></script><meta property="og:title" content="How to apply EUCAST rules">
<meta property="og:description" content="AMR">
<meta property="og:image" content="https://msberends.github.io/AMR/logo.svg">
<meta property="og:image" content="https://msberends.github.io/AMR/logo.png">
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</button>
<span class="navbar-brand">
<a class="navbar-link" href="../index.html">AMR (for R)</a>
<span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Latest development version">1.3.0.9015</span>
<span class="version label label-default" data-toggle="tooltip" data-placement="bottom" title="Latest development version">1.4.0</span>
</span>
</div>
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<blockquote>
<p><em>EUCAST expert rules are a tabulated collection of expert knowledge on intrinsic resistances, exceptional resistance phenotypes and interpretive rules that may be applied to antimicrobial susceptibility testing in order to reduce errors and make appropriate recommendations for reporting particular resistances.</em></p>
</blockquote>
<p>In Europe, a lot of medical microbiological laboratories already apply these rules (<a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES2015.20.2.21008">Brown <em>et al.</em>, 2015</a>). Our package features their latest insights on intrinsic resistance and exceptional phenotypes (version 10.0, 2020). Moreover, the <code><a href="../reference/eucast_rules.html">eucast_rules()</a></code> function we use for this purpose can also apply additional rules, like forcing <help title="ATC: J01CA01">ampicillin</help> = R in isolates when <help title="ATC: J01CR02">amoxicillin/clavulanic acid</help> = R.</p>
<p>In Europe, a lot of medical microbiological laboratories already apply these rules (<a href="https://www.eurosurveillance.org/content/10.2807/1560-7917.ES2015.20.2.21008">Brown <em>et al.</em>, 2015</a>). Our package features their latest insights on intrinsic resistance and unusual phenotypes (v3.2, 2020).</p>
<p>Moreover, the <code><a href="../reference/eucast_rules.html">eucast_rules()</a></code> function we use for this purpose can also apply additional rules, like forcing <help title="ATC: J01CA01">ampicillin</help> = R in isolates when <help title="ATC: J01CR02">amoxicillin/clavulanic acid</help> = R.</p>
</div>
<div id="examples" class="section level2">
<h2 class="hasAnchor">
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COL = <span class="st">"-"</span>, <span class="co"># Colistin</span>
CAZ = <span class="st">"-"</span>, <span class="co"># Ceftazidime</span>
CXM = <span class="st">"-"</span>, <span class="co"># Cefuroxime</span>
PEN = <span class="st">"S"</span>, <span class="co"># Penicillin G</span>
PEN = <span class="st">"S"</span>, <span class="co"># Benzylenicillin</span>
FOX = <span class="st">"S"</span>, <span class="co"># Cefoxitin</span>
stringsAsFactors = <span class="fl">FALSE</span>)
</pre></div>
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<div class="sourceCode" id="cb4"><pre class="downlit">
<span class="fu"><a href="../reference/eucast_rules.html">eucast_rules</a></span>(<span class="kw">data</span>)
</pre></div>
<pre><code># Warning: Not all columns with antimicrobial results are of class &lt;rsi&gt;.
# Transform eligible columns to class &lt;rsi&gt; on beforehand: your_data %&gt;% mutate_if(is.rsi.eligible, as.rsi)</code></pre>
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