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update mo algorithm
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@ -831,35 +831,50 @@ putative <- pathogens %>%
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established <- established[established %unlike% "unknown"]
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putative <- putative[putative %unlike% "unknown"]
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other_bacterial_genera <- c(established, putative) %>%
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established_genera <- established %>%
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strsplit(" ", fixed = TRUE) %>%
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sapply(function(x) x[1]) %>%
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sort() %>%
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unique()
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other_genera <- AMR:::MO_PREVALENT_GENERA %>%
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putative_genera <- putative %>%
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strsplit(" ", fixed = TRUE) %>%
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sapply(function(x) x[1]) %>%
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sort() %>%
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unique()
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nonbacterial_genera <- AMR:::MO_PREVALENT_GENERA %>%
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c(unlist(mo_current(.)),
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unlist(mo_synonyms(., keep_synonyms = FALSE))) %>%
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strsplit(" ", fixed = TRUE) %>%
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sapply(function(x) x[1]) %>%
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sort() %>%
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unique()
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other_genera <- other_genera[other_genera %unlike% "unknown"]
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nonbacterial_genera <- nonbacterial_genera[nonbacterial_genera %unlike% "unknown"]
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# update prevalence based on taxonomy (following the recent and thorough work of Bartlett et al., 2022)
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# see https://doi.org/10.1099/mic.0.001269
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taxonomy <- taxonomy %>%
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mutate(prevalence = case_when(
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# 'established' gets a 1 and means 'have infected at least three persons in three or more references'
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paste(genus, species) %in% established & rank %in% c("genus", "species", "subspecies") ~ 1.0,
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# 'putative' gets a 2 and means 'fewer than three known cases'
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paste(genus, species) %in% putative & rank %in% c("genus", "species", "subspecies") ~ 2.0,
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# other species from a genus in either group get a 2.5
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genus %in% other_bacterial_genera & rank %in% c("genus", "species", "subspecies") ~ 2.5,
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# 'established' means 'have infected at least three persons in three or more references'
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paste(genus, species) %in% established & rank %in% c("species", "subspecies") ~ 1.0,
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# other genera in the 'established' group
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genus %in% established_genera & rank == "genus" ~ 1.0,
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# 'putative' means 'fewer than three known cases'
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paste(genus, species) %in% putative & rank %in% c("species", "subspecies") ~ 1.25,
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# other genera in the 'putative' group
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genus %in% putative_genera & rank == "genus" ~ 1.25,
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# species and subspecies in 'established' and 'putative' groups
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genus %in% c(established_genera, putative_genera) & rank %in% c("species", "subspecies") ~ 1.5,
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# other species from a genus in either group
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genus %in% nonbacterial_genera & rank %in% c("genus", "species", "subspecies") ~ 1.5,
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# we keep track of prevalent genera too of non-bacterial species
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genus %in% AMR:::MO_PREVALENT_GENERA & kingdom != "Bacteria" & rank %in% c("genus", "species", "subspecies") ~ 2.5,
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# all others get a 3
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TRUE ~ 3.0))
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genus %in% AMR:::MO_PREVALENT_GENERA & kingdom != "Bacteria" & rank %in% c("genus", "species", "subspecies") ~ 1.5,
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# all others
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TRUE ~ 2.0))
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table(taxonomy$prevalence, useNA = "always")
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# (a lot will be removed further below)
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@ -825,6 +825,7 @@ serovars <- c("Aachen",
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"Leipzig",
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"Leith",
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"Lekke",
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"Lemmer",
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"Lene",
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"Leoben",
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"Leopoldville",
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