# ==================================================================== # # TITLE # # Antimicrobial Resistance (AMR) Analysis # # # # SOURCE # # https://github.com/msberends/AMR # # # # LICENCE # # (c) 2018-2020 Berends MS, Luz CF et al. # # # # This R package is free software; you can freely use and distribute # # it for both personal and commercial purposes under the terms of the # # GNU General Public License version 2.0 (GNU GPL-2), as published by # # the Free Software Foundation. # # # # We created this package for both routine data analysis and academic # # research and it was publicly released in the hope that it will be # # useful, but it comes WITHOUT ANY WARRANTY OR LIABILITY. # # Visit our website for more info: https://msberends.github.io/AMR. # # ==================================================================== # #' Get ATC properties from WHOCC website #' #' @inheritSection lifecycle Stable lifecycle #' @description Gets data from the WHO to determine properties of an ATC (e.g. an antibiotic) like name, defined daily dose (DDD) or standard unit. #' @param atc_code a character or character vector with ATC code(s) of antibiotic(s) #' @param property property of an ATC code. Valid values are `"ATC"`, `"Name"`, `"DDD"`, `"U"` (`"unit"`), `"Adm.R"`, `"Note"` and `groups`. For this last option, all hierarchical groups of an ATC code will be returned, see Examples. #' @param administration type of administration when using `property = "Adm.R"`, see Details #' @param url url of website of the WHO. The sign `%s` can be used as a placeholder for ATC codes. #' @param ... parameters to pass on to `atc_property` #' @details #' Options for parameter `administration`: #' #' - `"Implant"` = Implant #' - `"Inhal"` = Inhalation #' - `"Instill"` = Instillation #' - `"N"` = nasal #' - `"O"` = oral #' - `"P"` = parenteral #' - `"R"` = rectal #' - `"SL"` = sublingual/buccal #' - `"TD"` = transdermal #' - `"V"` = vaginal #' #' Abbreviations of return values when using `property = "U"` (unit): #' #' - `"g"` = gram #' - `"mg"` = milligram #' - `"mcg"`` = microgram #' - `"U"` = unit #' - `"TU"` = thousand units #' - `"MU"` = million units #' - `"mmol"` = millimole #' - `"ml"` = milliliter (e.g. eyedrops) #' #' **N.B. This function requires an internet connection and only works if the following packages are installed: `curl`, `rvest`, `xml2`.** #' @export #' @rdname atc_online #' @inheritSection AMR Read more on our website! #' @source #' @examples #' \dontrun{ #' # oral DDD (Defined Daily Dose) of amoxicillin #' atc_online_property("J01CA04", "DDD", "O") #' # parenteral DDD (Defined Daily Dose) of amoxicillin #' atc_online_property("J01CA04", "DDD", "P") #' #' atc_online_property("J01CA04", property = "groups") # search hierarchical groups of amoxicillin #' # [1] "ANTIINFECTIVES FOR SYSTEMIC USE" #' # [2] "ANTIBACTERIALS FOR SYSTEMIC USE" #' # [3] "BETA-LACTAM ANTIBACTERIALS, PENICILLINS" #' # [4] "Penicillins with extended spectrum" #' } atc_online_property <- function(atc_code, property, administration = "O", url = "https://www.whocc.no/atc_ddd_index/?code=%s&showdescription=no") { has_internet <- import_fn("has_internet", "curl") html_attr <- import_fn("html_attr", "rvest") html_children <- import_fn("html_children", "rvest") html_node <- import_fn("html_node", "rvest") html_nodes <- import_fn("html_nodes", "rvest") html_table <- import_fn("html_table", "rvest") html_text <- import_fn("html_text", "rvest") read_html <- import_fn("read_html", "xml2") check_dataset_integrity() if (!all(atc_code %in% antibiotics)) { atc_code <- as.character(ab_atc(atc_code)) } if (!has_internet()) { message("There appears to be no internet connection.") return(rep(NA, length(atc_code))) } stop_if(length(property) != 1L, "`property` must be of length 1") stop_if(length(administration) != 1L, "`administration` must be of length 1") # also allow unit as property if (property %like% "unit") { property <- "U" } # validation of properties valid_properties <- c("ATC", "Name", "DDD", "U", "Adm.R", "Note", "groups") valid_properties.bak <- valid_properties property <- tolower(property) valid_properties <- tolower(valid_properties) stop_ifnot(property %in% valid_properties, "Invalid `property`, use one of ", paste(valid_properties.bak, collapse = ", ")) if (property == "ddd") { returnvalue <- rep(NA_real_, length(atc_code)) } else if (property == "groups") { returnvalue <- list() } else { returnvalue <- rep(NA_character_, length(atc_code)) } progress <- progress_estimated(n = length(atc_code), 3) on.exit(close(progress)) for (i in seq_len(length(atc_code))) { progress$tick() atc_url <- sub("%s", atc_code[i], url, fixed = TRUE) if (property == "groups") { tbl <- read_html(atc_url) %>% html_node("#content") %>% html_children() %>% html_node("a") # get URLS of items hrefs <- tbl %>% html_attr("href") # get text of items texts <- tbl %>% html_text() # select only text items where URL like "code=" texts <- texts[grepl("?code=", tolower(hrefs), fixed = TRUE)] # last one is antibiotics, skip it texts <- texts[seq_len(length(texts)) - 1] returnvalue <- c(list(texts), returnvalue) } else { tbl <- read_html(atc_url) %>% html_nodes("table") %>% html_table(header = TRUE) %>% as.data.frame(stringsAsFactors = FALSE) # case insensitive column names colnames(tbl) <- gsub("^atc.*", "atc", tolower(colnames(tbl))) if (length(tbl) == 0) { warning("ATC not found: ", atc_code[i], ". Please check ", atc_url, ".", call. = FALSE) returnvalue[i] <- NA next } if (property %in% c("atc", "name")) { # ATC and name are only in first row returnvalue[i] <- tbl[1, property] } else { if (!"adm.r" %in% colnames(tbl) | is.na(tbl[1, "adm.r"])) { returnvalue[i] <- NA next } else { for (j in seq_len(nrow(tbl))) { if (tbl[j, "adm.r"] == administration) { returnvalue[i] <- tbl[j, property] } } } } } } if (property == "groups" & length(returnvalue) == 1) { returnvalue <- returnvalue[[1]] } returnvalue } #' @rdname atc_online #' @export atc_online_groups <- function(atc_code, ...) { atc_online_property(atc_code = atc_code, property = "groups", ...) } #' @rdname atc_online #' @export atc_online_ddd <- function(atc_code, ...) { atc_online_property(atc_code = atc_code, property = "ddd", ...) }