# -------------------------------------------------------------------------------------------------------------------------------
# For editing this EUCAST reference file, these values can all be used for targeting antibiotics:
# aminoglycosides, aminopenicillins, antifungals, antimycobacterials, betalactams, betalactams_with_inhibitor, carbapenems, cephalosporins, cephalosporins_1st, cephalosporins_2nd, cephalosporins_3rd, cephalosporins_4th, cephalosporins_5th, cephalosporins_except_CAZ, fluoroquinolones, glycopeptides, glycopeptides_except_lipo, lincosamides, lipoglycopeptides, macrolides, oxazolidinones, penicillins, polymyxins, quinolones, streptogramins, tetracyclines, tetracyclines_except_TGC, trimethoprims, ureidopenicillins
# and all separate EARS-Net letter codes such as AMC. They can be separated by comma: 'AMC, fluoroquinolones'.
# The 'if_mo_property' column can be any column name from the AMR::microorganisms data set, or 'genus_species' or 'gramstain'. If 'this_value' exists in AMR::microorganisms.groups$mo_group_name it will be expanded in eucast_rules() to all relevant species occuring in microorganisms.groups$mo_name before further processing of the line in this file.
# The like.is.one_of column must be 'like' or 'is' or 'one_of' ('like' will read the 'this_value' column as regular expression)
# The EUCAST guideline contains references to the 'Burkholderia cepacia complex'. All species in this group are noted on the 'B.cepacia' sheet of the EUCAST Clinical Breakpoint v.10.0 Excel file of 2020 and later
# >>>>> IF YOU WANT TO IMPORT THIS FILE INTO YOUR OWN SOFTWARE, HAVE THE FIRST 9 LINES SKIPPED <<<<<
# -------------------------------------------------------------------------------------------------------------------------------			
if_mo_property	like.is.one_of	this_value	and_these_antibiotics	have_these_values	then_change_these_antibiotics	to_value	reference.rule	reference.rule_group	reference.version	note
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints	10	
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints	10	
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints	10	
genus	is	Staphylococcus	PEN, FOX	S	betalactams_with_inhibitor	S	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	PEN, FOX	R, S	OXA, FLC	S	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	FOX	R	betalactams	R	Staphylococcus	Breakpoints	10	
genus_species	is	Staphylococcus saprophyticus	AMP	S	AMX, AMC, PIP, TZP	S	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	FOX	S	carbapenems, cephalosporins_except_CAZ	S	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	FOX	I	carbapenems, cephalosporins_except_CAZ	I	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	FOX	R	carbapenems, cephalosporins_except_CAZ	R	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	NOR	S	CIP, LVX, MFX, OFX	S	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	ERY	S	AZM, CLR, RXT	S	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	ERY	I	AZM, CLR, RXT	I	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	ERY	R	AZM, CLR, RXT	R	Staphylococcus	Breakpoints	10	
genus	is	Staphylococcus	TCY	S	DOX, MNO	S	Staphylococcus	Breakpoints	10	
genus	is	Enterococcus	AMP	S	AMX, AMC, PIP, TZP	S	Enterococcus	Breakpoints	10	
genus	is	Enterococcus	AMP	I	AMX, AMC, PIP, TZP	I	Enterococcus	Breakpoints	10	
genus	is	Enterococcus	AMP	R	AMX, AMC, PIP, TZP	R	Enterococcus	Breakpoints	10	
genus	is	Enterococcus	NOR	S	CIP, LVX	S	Enterococcus	Breakpoints	10	
genus	is	Enterococcus	NOR	I	CIP, LVX	I	Enterococcus	Breakpoints	10	
genus	is	Enterococcus	NOR	R	CIP, LVX	R	Enterococcus	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	S	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	I	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	I	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	R	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	R	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	S	MFX	S	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	S	LVX	I	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	S	AZM, CLR, RXT	S	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	I	AZM, CLR, RXT	I	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	R	AZM, CLR, RXT	R	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	TCY	S	DOX, MNO	S	Streptococcus groups A, B, C, G	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	AMP	S	AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	AMP	I	AMX, AMC, PIP, TZP	I	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	AMP	R	AMX, AMC, PIP, TZP	R	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	NOR	S	MFX	S	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	NOR	S	LVX	I	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	ERY	S	AZM, CLR, RXT	S	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	ERY	I	AZM, CLR, RXT	I	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	ERY	R	AZM, CLR, RXT	R	Streptococcus pneumoniae	Breakpoints	10	
genus_species	is	Streptococcus pneumoniae	TCY	S	DOX, MNO	S	Streptococcus pneumoniae	Breakpoints	10	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints	10	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	AMP	S	AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints	10	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	AMP	I	AMX, AMC, PIP, TZP	I	Viridans group streptococci	Breakpoints	10	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	AMP	R	AMX, AMC, PIP, TZP	R	Viridans group streptococci	Breakpoints	10	
genus_species	is	Haemophilus influenzae	AMP	S	AMX, PIP	S	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	AMP	I	AMX, PIP	I	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	AMP	R	AMX, PIP	R	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	AMC	S	TZP	S	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	AMC	I	TZP	I	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	AMC	R	TZP	R	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	NAL	S	CIP, LVX, MFX, OFX	S	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Haemophilus influenzae	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	NAL	S	CIP, LVX, MFX, OFX	S	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	ERY	S	AZM, CLR, RXT	S	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	ERY	I	AZM, CLR, RXT	I	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	ERY	R	AZM, CLR, RXT	R	Moraxella catarrhalis	Breakpoints	10	
genus_species	is	Moraxella catarrhalis	TCY	S	DOX, MNO	S	Moraxella catarrhalis	Breakpoints	10	
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Clostridioides, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	S	AMP, AMX, PIP, TZP, TIC	S	Anaerobic Gram-positives	Breakpoints	10	
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Clostridioides, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	I	AMP, AMX, PIP, TZP, TIC	I	Anaerobic Gram-positives	Breakpoints	10	
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Clostridioides, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	R	AMP, AMX, PIP, TZP, TIC	R	Anaerobic Gram-positives	Breakpoints	10	
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	S	AMP, AMX, PIP, TZP, TIC	S	Anaerobic Gram-negatives	Breakpoints	10	
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	I	AMP, AMX, PIP, TZP, TIC	I	Anaerobic Gram-negatives	Breakpoints	10	
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	R	AMP, AMX, PIP, TZP, TIC	R	Anaerobic Gram-negatives	Breakpoints	10	
genus_species	is	Pasteurella multocida	PEN	S	AMP, AMX	S	Pasteurella multocida	Breakpoints	10	
genus_species	is	Pasteurella multocida	PEN	I	AMP, AMX	I	Pasteurella multocida	Breakpoints	10	
genus_species	is	Pasteurella multocida	PEN	R	AMP, AMX	R	Pasteurella multocida	Breakpoints	10	
genus_species	is	Campylobacter coli	ERY	S	AZM, CLR	S	Campylobacter coli	Breakpoints	10	
genus_species	is	Campylobacter coli	ERY	I	AZM, CLR	I	Campylobacter coli	Breakpoints	10	
genus_species	is	Campylobacter coli	ERY	R	AZM, CLR	R	Campylobacter coli	Breakpoints	10	
genus_species	is	Campylobacter coli	TCY	S	DOX	S	Campylobacter coli	Breakpoints	10	
genus_species	is	Campylobacter coli	TCY	I	DOX	I	Campylobacter coli	Breakpoints	10	
genus_species	is	Campylobacter coli	TCY	R	DOX	R	Campylobacter coli	Breakpoints	10	
genus_species	is	Campylobacter jejuni	ERY	S	AZM, CLR	S	Campylobacter jejuni	Breakpoints	10	
genus_species	is	Campylobacter jejuni	ERY	I	AZM, CLR	I	Campylobacter jejuni	Breakpoints	10	
genus_species	is	Campylobacter jejuni	ERY	R	AZM, CLR	R	Campylobacter jejuni	Breakpoints	10	
genus_species	is	Campylobacter jejuni	TCY	S	DOX	S	Campylobacter jejuni	Breakpoints	10	
genus_species	is	Campylobacter jejuni	TCY	I	DOX	I	Campylobacter jejuni	Breakpoints	10	
genus_species	is	Campylobacter jejuni	TCY	R	DOX	R	Campylobacter jejuni	Breakpoints	10	
genus_species	is	Aerococcus sanguinicola	NOR	S	fluoroquinolones	S	Aerococcus sanguinicola	Breakpoints	10	
genus_species	is	Aerococcus sanguinicola	NOR	I	fluoroquinolones	I	Aerococcus sanguinicola	Breakpoints	10	
genus_species	is	Aerococcus sanguinicola	NOR	R	fluoroquinolones	R	Aerococcus sanguinicola	Breakpoints	10	
genus_species	is	Aerococcus sanguinicola	CIP	S	LVX	S	Aerococcus sanguinicola	Breakpoints	10	
genus_species	is	Aerococcus sanguinicola	CIP	I	LVX	I	Aerococcus sanguinicola	Breakpoints	10	
genus_species	is	Aerococcus sanguinicola	CIP	R	LVX	R	Aerococcus urinae	Breakpoints	10	
genus_species	is	Aerococcus urinae	NOR	S	fluoroquinolones	S	Aerococcus urinae	Breakpoints	10	
genus_species	is	Aerococcus urinae	NOR	I	fluoroquinolones	I	Aerococcus urinae	Breakpoints	10	
genus_species	is	Aerococcus urinae	NOR	R	fluoroquinolones	R	Aerococcus urinae	Breakpoints	10	
genus_species	is	Aerococcus urinae	CIP	S	LVX	S	Aerococcus urinae	Breakpoints	10	
genus_species	is	Aerococcus urinae	CIP	I	LVX	I	Aerococcus urinae	Breakpoints	10	
genus_species	is	Aerococcus urinae	CIP	R	LVX	R	Aerococcus urinae	Breakpoints	10	
genus_species	is	Kingella kingae	PEN	S	AMP, AMX	S	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	PEN	I	AMP, AMX	I	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	PEN	R	AMP, AMX	R	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	ERY	S	AZM, CLR	S	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	ERY	I	AZM, CLR	I	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	ERY	R	AZM, CLR	R	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	TCY	I	DOX	I	Kingella kingae	Breakpoints	10	
genus_species	is	Kingella kingae	TCY	R	DOX	R	Kingella kingae	Breakpoints	10	
genus_species	is	Burkholderia pseudomallei	TCY	S	DOX	S	Burkholderia pseudomallei	Breakpoints	10	
genus_species	is	Burkholderia pseudomallei	TCY	I	DOX	I	Burkholderia pseudomallei	Breakpoints	10	
genus_species	is	Burkholderia pseudomallei	TCY	R	DOX	R	Burkholderia pseudomallei	Breakpoints	10	
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints	11	
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints	11	
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints	11	
genus	is	Staphylococcus	PEN, FOX	S	betalactams_with_inhibitor	S	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	PEN, FOX	R, S	OXA, FLC	S	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	FOX	R	betalactams	R	Staphylococcus	Breakpoints	11	
genus_species	is	Staphylococcus saprophyticus	AMP	S	AMX, AMC, PIP, TZP	S	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	FOX	S	carbapenems, cephalosporins_except_CAZ	S	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	FOX	I	carbapenems, cephalosporins_except_CAZ	I	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	FOX	R	carbapenems, cephalosporins_except_CAZ	R	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	NOR	S	CIP, LVX, MFX, OFX	S	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	ERY	S	AZM, CLR, RXT	S	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	ERY	I	AZM, CLR, RXT	I	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	ERY	R	AZM, CLR, RXT	R	Staphylococcus	Breakpoints	11	
genus	is	Staphylococcus	TCY	S	DOX, MNO	S	Staphylococcus	Breakpoints	11	
genus	is	Enterococcus	AMP	S	AMX, AMC, PIP, TZP	S	Enterococcus	Breakpoints	11	
genus	is	Enterococcus	AMP	I	AMX, AMC, PIP, TZP	I	Enterococcus	Breakpoints	11	
genus	is	Enterococcus	AMP	R	AMX, AMC, PIP, TZP	R	Enterococcus	Breakpoints	11	
genus	is	Enterococcus	NOR	S	CIP, LVX	S	Enterococcus	Breakpoints	11	
genus	is	Enterococcus	NOR	I	CIP, LVX	I	Enterococcus	Breakpoints	11	
genus	is	Enterococcus	NOR	R	CIP, LVX	R	Enterococcus	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	S	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	I	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	I	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	R	aminopenicillins, ureidopenicillins, cephalosporins_except_CAZ, carbapenems, FLC, AMC	R	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	S	MFX	S	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	S	LVX	I	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	S	AZM, CLR, RXT	S	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	I	AZM, CLR, RXT	I	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	R	AZM, CLR, RXT	R	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	TCY	S	DOX, MNO	S	Streptococcus groups A, B, C, G	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	AMP	S	AMX, AMC, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	AMP	I	AMX, AMC, PIP, TZP	I	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	AMP	R	AMX, AMC, PIP, TZP	R	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	NOR	S	MFX	S	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	NOR	S	LVX	I	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	ERY	S	AZM, CLR, RXT	S	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	ERY	I	AZM, CLR, RXT	I	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	ERY	R	AZM, CLR, RXT	R	Streptococcus pneumoniae	Breakpoints	11	
genus_species	is	Streptococcus pneumoniae	TCY	S	DOX, MNO	S	Streptococcus pneumoniae	Breakpoints	11	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints	11	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	AMP	S	AMX, AMC, PIP, TZP	S	Viridans group streptococci	Breakpoints	11	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	AMP	I	AMX, AMC, PIP, TZP	I	Viridans group streptococci	Breakpoints	11	
genus_species	like	^Streptococcus (anginosus|australis|bovis|constellatus|cristatus|equinus|gallolyticus|gordonii|infantarius|infantis|intermedius|mitis|mutans|oligofermentans|oralis|parasanguinis|peroris|pseudopneumoniae|salivarius|sanguinis|sinensis|sobrinus|thermophilus|vestibularis|viridans)$	AMP	R	AMX, AMC, PIP, TZP	R	Viridans group streptococci	Breakpoints	11	
genus_species	is	Haemophilus influenzae	AMP	S	AMX, PIP	S	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	AMP	I	AMX, PIP	I	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	AMP	R	AMX, PIP	R	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	PEN	S	AMP, AMX, AMC, PIP, TZP	S	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	AMC	S	TZP	S	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	AMC	I	TZP	I	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	AMC	R	TZP	R	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	NAL	S	CIP, LVX, MFX, OFX	S	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Haemophilus influenzae	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	NAL	S	CIP, LVX, MFX, OFX	S	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	ERY	S	AZM, CLR, RXT	S	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	ERY	I	AZM, CLR, RXT	I	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	ERY	R	AZM, CLR, RXT	R	Moraxella catarrhalis	Breakpoints	11	
genus_species	is	Moraxella catarrhalis	TCY	S	DOX, MNO	S	Moraxella catarrhalis	Breakpoints	11	
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Clostridioides, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	S	AMP, AMX, PIP, TIC	S	Anaerobic Gram-positives	Breakpoints	11	
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Clostridioides, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	I	AMP, AMX, PIP, TIC	I	Anaerobic Gram-positives	Breakpoints	11	
genus	one_of	Actinomyces, Bifidobacterium, Clostridium, Clostridioides, Cutibacterium, Eggerthella, Eubacterium, Lactobacillus, Propionibacterium	PEN	R	AMP, AMX, PIP, TIC	R	Anaerobic Gram-positives	Breakpoints	11	
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	S	AMP, AMX, PIP, TIC	S	Anaerobic Gram-negatives	Breakpoints	11	
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	I	AMP, AMX, PIP, TIC	I	Anaerobic Gram-negatives	Breakpoints	11	
genus	one_of	Bacteroides, Bilophila , Fusobacterium, Mobiluncus, Porphyromonas, Prevotella	PEN	R	AMP, AMX, PIP, TIC	R	Anaerobic Gram-negatives	Breakpoints	11	
genus_species	is	Pasteurella multocida	PEN	S	AMP, AMX	S	Pasteurella multocida	Breakpoints	11	
genus_species	is	Pasteurella multocida	PEN	I	AMP, AMX	I	Pasteurella multocida	Breakpoints	11	
genus_species	is	Pasteurella multocida	PEN	R	AMP, AMX	R	Pasteurella multocida	Breakpoints	11	
genus_species	is	Campylobacter coli	ERY	S	AZM, CLR	S	Campylobacter coli	Breakpoints	11	
genus_species	is	Campylobacter coli	ERY	I	AZM, CLR	I	Campylobacter coli	Breakpoints	11	
genus_species	is	Campylobacter coli	ERY	R	AZM, CLR	R	Campylobacter coli	Breakpoints	11	
genus_species	is	Campylobacter coli	TCY	S	DOX	S	Campylobacter coli	Breakpoints	11	
genus_species	is	Campylobacter coli	TCY	I	DOX	I	Campylobacter coli	Breakpoints	11	
genus_species	is	Campylobacter coli	TCY	R	DOX	R	Campylobacter coli	Breakpoints	11	
genus_species	is	Campylobacter jejuni	ERY	S	AZM, CLR	S	Campylobacter jejuni	Breakpoints	11	
genus_species	is	Campylobacter jejuni	ERY	I	AZM, CLR	I	Campylobacter jejuni	Breakpoints	11	
genus_species	is	Campylobacter jejuni	ERY	R	AZM, CLR	R	Campylobacter jejuni	Breakpoints	11	
genus_species	is	Campylobacter jejuni	TCY	S	DOX	S	Campylobacter jejuni	Breakpoints	11	
genus_species	is	Campylobacter jejuni	TCY	I	DOX	I	Campylobacter jejuni	Breakpoints	11	
genus_species	is	Campylobacter jejuni	TCY	R	DOX	R	Campylobacter jejuni	Breakpoints	11	
genus_species	is	Aerococcus sanguinicola	NOR	S	fluoroquinolones	S	Aerococcus sanguinicola	Breakpoints	11	
genus_species	is	Aerococcus sanguinicola	NOR	I	fluoroquinolones	I	Aerococcus sanguinicola	Breakpoints	11	
genus_species	is	Aerococcus sanguinicola	NOR	R	fluoroquinolones	R	Aerococcus sanguinicola	Breakpoints	11	
genus_species	is	Aerococcus sanguinicola	CIP	S	LVX	S	Aerococcus sanguinicola	Breakpoints	11	
genus_species	is	Aerococcus sanguinicola	CIP	I	LVX	I	Aerococcus sanguinicola	Breakpoints	11	
genus_species	is	Aerococcus sanguinicola	CIP	R	LVX	R	Aerococcus urinae	Breakpoints	11	
genus_species	is	Aerococcus urinae	NOR	S	fluoroquinolones	S	Aerococcus urinae	Breakpoints	11	
genus_species	is	Aerococcus urinae	NOR	I	fluoroquinolones	I	Aerococcus urinae	Breakpoints	11	
genus_species	is	Aerococcus urinae	NOR	R	fluoroquinolones	R	Aerococcus urinae	Breakpoints	11	
genus_species	is	Aerococcus urinae	CIP	S	LVX	S	Aerococcus urinae	Breakpoints	11	
genus_species	is	Aerococcus urinae	CIP	I	LVX	I	Aerococcus urinae	Breakpoints	11	
genus_species	is	Aerococcus urinae	CIP	R	LVX	R	Aerococcus urinae	Breakpoints	11	
genus_species	is	Kingella kingae	PEN	S	AMP, AMX	S	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	PEN	I	AMP, AMX	I	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	PEN	R	AMP, AMX	R	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	ERY	S	AZM, CLR	S	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	ERY	I	AZM, CLR	I	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	ERY	R	AZM, CLR	R	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	TCY	I	DOX	I	Kingella kingae	Breakpoints	11	
genus_species	is	Kingella kingae	TCY	R	DOX	R	Kingella kingae	Breakpoints	11	
genus_species	is	Burkholderia pseudomallei	TCY	S	DOX	S	Burkholderia pseudomallei	Breakpoints	11	
genus_species	is	Burkholderia pseudomallei	TCY	I	DOX	I	Burkholderia pseudomallei	Breakpoints	11	
genus_species	is	Burkholderia pseudomallei	TCY	R	DOX	R	Burkholderia pseudomallei	Breakpoints	11	
genus	is	Bacillus	NOR	S	fluoroquinolones	S	Bacillus	Breakpoints	11	added in 11
genus	is	Bacillus	NOR	I	fluoroquinolones	I	Bacillus	Breakpoints	11	added in 11
genus	is	Bacillus	NOR	R	fluoroquinolones	R	Bacillus	Breakpoints	11	added in 11
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints	12	
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints	12	
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints	12	
order	is	Enterobacterales	LEX	S	CZO	I	Enterobacterales (Order)	Breakpoints	12	
order	is	Enterobacterales	CFR	S	CZO	I	Enterobacterales (Order)	Breakpoints	12	
genus	is	Salmonella	PEF-S	S	CIP	S	Enterobacterales (Order)	Breakpoints	12	
genus	is	Salmonella	PEF-S	I	CIP	I	Enterobacterales (Order)	Breakpoints	12	
genus	is	Salmonella	PEF-S	R	CIP	R	Enterobacterales (Order)	Breakpoints	12	
genus_species	is	Yersinia enterocolitica	TCY	S	DOX	S	Enterobacterales (Order)	Breakpoints	12	
genus_species	is	Yersinia enterocolitica	TCY	I	DOX	I	Enterobacterales (Order)	Breakpoints	12	
genus_species	is	Yersinia enterocolitica	TCY	R	DOX	R	Enterobacterales (Order)	Breakpoints	12	
genus_species	is	Staphylococcus aureus	FOX-S	R	penicillins	R	Staphylococcus	Breakpoints	12	See last sentence: Isolates that test resistant to cefoxitin are resistant to all penicillins
genus_species	is	Staphylococcus aureus	"PEN, FOX-S"	"S, S"	penicillins	S	Staphylococcus	Breakpoints	12	
genus_species	is	Staphylococcus aureus	"PEN, FOX-S"	"R, S"	"betalactams_with_inhibitor, isoxazolylpenicillins, NAF"	S	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	FOX-S	R	"PEN, PHN, AMP, AMX, PIP, TIC"	R	Staphylococcus	Breakpoints	12	
genus_species	is	Staphylococcus saprophyticus	AMP	S	"AMP, SAM, AMX, AMC, PIP, TZP"	S	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	FOX-S	S	"BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP"	S	Staphylococcus	Breakpoints	12	"sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c(""cefalexin"", ""ceftazidim"", ""ceftazidim/avibactam"", ""ceftibuten"", ""ceftolozan/tazobactam""))]))"
genus	is	Staphylococcus	FOX-S	I	"BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP"	I	Staphylococcus	Breakpoints	12	"sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c(""cefalexin"", ""ceftazidim"", ""ceftazidim/avibactam"", ""ceftibuten"", ""ceftolozan/tazobactam""))]))"
genus	is	Staphylococcus	FOX-S	R	"BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP"	R	Staphylococcus	Breakpoints	12	"sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c(""cefalexin"", ""ceftazidim"", ""ceftazidim/avibactam"", ""ceftibuten"", ""ceftolozan/tazobactam""))]))"
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	R	"PEN, PHN, AMP, AMX, PIP, TIC"	R	Staphylococcus	Breakpoints	12	
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	S	"BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP"	S	Staphylococcus	Breakpoints	12	"sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c(""cefalexin"", ""ceftazidim"", ""ceftazidim/avibactam"", ""ceftibuten"", ""ceftolozan/tazobactam""))]))"
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	I	"BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP"	I	Staphylococcus	Breakpoints	12	"sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c(""cefalexin"", ""ceftazidim"", ""ceftazidim/avibactam"", ""ceftibuten"", ""ceftolozan/tazobactam""))]))"
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	R	"BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP"	R	Staphylococcus	Breakpoints	12	"sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c(""cefalexin"", ""ceftazidim"", ""ceftazidim/avibactam"", ""ceftibuten"", ""ceftolozan/tazobactam""))]))"
genus_species	is	Staphylococcus aureus	FOX-S	S	CPT	S	Staphylococcus	Breakpoints	12	
genus_species	is	Staphylococcus aureus	FOX-S	S	BPR	S	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	FOX-S	S	carbapenems	S	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	FOX-S	I	carbapenems	I	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	FOX-S	R	carbapenems	R	Staphylococcus	Breakpoints	12	
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	S	carbapenems	S	Staphylococcus	Breakpoints	12	"Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method"
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	I	carbapenems	I	Staphylococcus	Breakpoints	12	"Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method"
genus_species	one_of	"Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans"	OXA-S	R	carbapenems	R	Staphylococcus	Breakpoints	12	"Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method"
genus	is	Staphylococcus	NOR-S	S	MFX	S	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	NOR-S	S	"CIP, LVX"	I	Staphylococcus	Breakpoints	12	
genus_species	is	Staphylococcus aureus	VAN	S	"DAL, ORI"	S	Staphylococcus	Breakpoints	12	
genus_species	is	Staphylococcus aureus	"FOX-S, VAN"	"R, S"	TLV	S	Staphylococcus	Breakpoints	12	MRSA isolates are in this file safely denoted as FOX resistant
genus	is	Staphylococcus	ERY	S	"AZM, CLR, RXT"	S	Staphylococcus	Breakpoints	12	
genus	is	Staphylococcus	TCY-S	S	"DOX, MNO"	S	Staphylococcus	Breakpoints	12	
genus	is	Enterococcus	AMP	S	"AMP, SAM, AMX, AMC, PIP, TZP"	S	Enterococcus	Breakpoints	12	
genus	is	Enterococcus	AMP	I	"AMP, SAM, AMX, AMC, PIP, TZP"	I	Enterococcus	Breakpoints	12	
genus	is	Enterococcus	AMP	R	"AMP, SAM, AMX, AMC, PIP, TZP"	R	Enterococcus	Breakpoints	12	
genus	is	Enterococcus	NOR-S	S	"CIP, LVX"	S	Enterococcus	Breakpoints	12	
genus	is	Enterococcus	NOR-S	I	"CIP, LVX"	I	Enterococcus	Breakpoints	12	
genus	is	Enterococcus	NOR-S	R	"CIP, LVX"	R	Enterococcus	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group C, Streptococcus Group G"	PEN	S	penicillins	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group C, Streptococcus Group G"	PEN	I	penicillins	I	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group C, Streptococcus Group G"	PEN	R	penicillins	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	is	Streptococcus Group B	PEN	S	"AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP"	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	"penicillins()[!penicillins() %in% c(""PHN"", isoxazolylpenicillins())]"
genus_species	is	Streptococcus Group B	PEN	I	"AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP"	I	"Streptococcus groups A, B, C, G"	Breakpoints	12	"penicillins()[!penicillins() %in% c(""PHN"", isoxazolylpenicillins())]"
genus_species	is	Streptococcus Group B	PEN	R	"AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP"	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	"penicillins()[!penicillins() %in% c(""PHN"", isoxazolylpenicillins())]"
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	PEN	S	cephalosporins	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	PEN	I	cephalosporins	I	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	PEN	R	cephalosporins	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	PEN	S	carbapenems	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	PEN	I	carbapenems	I	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	PEN	R	carbapenems	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	NOR-S	S	MFX	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	NOR-S	S	LVX	I	"Streptococcus groups A, B, C, G"	Breakpoints	12	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	NOR-S	R	"MFX, LVX"	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	VAN	S	"DAL, ORI"	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	ERY	S	"AZM, CLR, RXT"	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	ERY	R	"AZM, CLR, RXT"	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	TCY-S	S	"DOX, MNO"	S	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	one_of	"Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G"	TCY-S	R	"DOX, MNO"	R	"Streptococcus groups A, B, C, G"	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	OXA-S	S	"AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PHN, PIP, SAM, TZP"	S	Streptococcus pneumoniae	Breakpoints	12	"x <- unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2022"" & clinical_breakpoints$mo == as.mo(""S. pneumoniae"") & clinical_breakpoints$ab != as.ab(""cefaclor""))]); sort(c(x[x %in% betalactams()], ""SAM"", ""PIP"", ""TZP"", ""PHN"", ""IMR"", ""MEV""))"
genus_species	is	Streptococcus pneumoniae	PEN	S	"AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PHN, PIP, SAM, TZP"	S	Streptococcus pneumoniae	Breakpoints	12	"x <- unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2022"" & clinical_breakpoints$mo == as.mo(""S. pneumoniae"") & clinical_breakpoints$ab != as.ab(""cefaclor""))]); sort(c(x[x %in% betalactams()], ""SAM"", ""PIP"", ""TZP"", ""PHN"", ""IMR"", ""MEV""))"
genus_species	is	Streptococcus pneumoniae	OXA-S	S	CEC	I	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	PEN	S	CEC	I	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	OXA-S	R	"PEN, PHN"	R	Streptococcus pneumoniae	Breakpoints	12	from flowchart: when OXA < 20 or PEN > 0.06
genus_species	is	Streptococcus pneumoniae	PEN	R	PHN	R	Streptococcus pneumoniae	Breakpoints	12	from flowchart: when OXA < 20 or PEN > 0.06
genus_species	is	Streptococcus pneumoniae	AMP	S	"AMX, AMC, SAM, PIP, TZP"	S	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	AMP	I	"AMX, AMC, SAM, PIP, TZP"	I	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	AMP	R	"AMX, AMC, SAM, PIP, TZP"	R	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	NOR-S	S	MFX	S	Streptococcus pneumoniae	Breakpoints	12	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	NOR-S	S	LVX	I	Streptococcus pneumoniae	Breakpoints	12	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	NOR-S	R	"MFX, LVX"	R	Streptococcus pneumoniae	Breakpoints	12	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	ERY	S	"AZM, CLR, RXT"	S	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	ERY	R	"AZM, CLR, RXT"	R	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	TCY-S	S	"DOX, MNO"	S	Streptococcus pneumoniae	Breakpoints	12	
genus_species	is	Streptococcus pneumoniae	TCY-S	R	"DOX, MNO"	R	Streptococcus pneumoniae	Breakpoints	12	
genus_species	one_of	"Viridans Group Streptococcus (VGS)"	PEN-S	S	"AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PIP, SAM, TZP"	S	Viridans group streptococci	Breakpoints	12	"paste(""Streptococcus"", mo_species(microorganisms.groups$mo[which(microorganisms.groups$mo_group == ""B_STRPT_VIRI"")]), collapse = "", "")"
genus_species	one_of	"Viridans Group Streptococcus (VGS)"	PEN-S	R	"AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PIP, SAM, TZP"	R	Viridans group streptococci	Breakpoints	12	"paste(""Streptococcus"", mo_species(microorganisms.groups$mo[which(microorganisms.groups$mo_group == ""B_STRPT_VIRI"")]), collapse = "", "")"
genus_species	one_of	"Viridans Group Streptococcus (VGS)"	AMP	S	"AMX, AMC, SAM, PIP, TZP"	S	Viridans group streptococci	Breakpoints	12	"paste(""Streptococcus"", mo_species(microorganisms.groups$mo[which(microorganisms.groups$mo_group == ""B_STRPT_VIRI"")]), collapse = "", "")"
genus_species	one_of	"Viridans Group Streptococcus (VGS)"	AMP	I	"AMX, AMC, SAM, PIP, TZP"	I	Viridans group streptococci	Breakpoints	12	"paste(""Streptococcus"", mo_species(microorganisms.groups$mo[which(microorganisms.groups$mo_group == ""B_STRPT_VIRI"")]), collapse = "", "")"
genus_species	one_of	"Viridans Group Streptococcus (VGS)"	AMP	R	"AMX, AMC, SAM, PIP, TZP"	R	Viridans group streptococci	Breakpoints	12	"paste(""Streptococcus"", mo_species(microorganisms.groups$mo[which(microorganisms.groups$mo_group == ""B_STRPT_VIRI"")]), collapse = "", "")"
genus_species	is	Haemophilus influenzae	PEN-S	S	"AMC, AMP, AMX, CFM, CPD, CPT, CRO, CTB, CTX, CXM, CZT, DOR, ETP, FEP, IMR, IPM, MEM, MEV, PEN, SAM, TZP"	S	Haemophilus influenzae	Breakpoints	12	"x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2022"" & clinical_breakpoints$mo == as.mo(""H. influenzae""))]), ""IMR"", ""MEV""); sort(x[x %in% betalactams()])"
genus_species	is	Haemophilus influenzae	"PEN-S, BLA-S"	"R, R"	"AMP, AMX, PIP"	R	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	AMC	S	SAM	S	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	AMC	I	SAM	I	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	AMC	R	SAM	R	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	NAL-S	S	"CIP, LVX, MFX, OFX"	S	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	NAL-S	I	"CIP, LVX, MFX, OFX"	I	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	NAL-S	R	"CIP, LVX, MFX, OFX"	R	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	TCY	S	"DOX, MNO"	S	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Haemophilus influenzae	TCY	R	"DOX, MNO"	R	Haemophilus influenzae	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	BLA-S	R	"AMP, AMX, APL, APX, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CLO, CRB, CRN, DIC, EPC, FLC, HET, LEN, MEC, MET, MEZ, MTM, NAF, OXA, PEN, PHE, PHN, PIP, PME, PNM, PRB, PRC, PRP, PVM, SBC, SLT6, SRX, TAL, TEM, TIC"	R	Moraxella catarrhalis	Breakpoints	12	penicillins()[!penicillins() %in% betalactams_with_inhibitor()]
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	NAL-S	S	"CIP, LVX, MFX, OFX"	S	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	NAL-S	R	"CIP, LVX, MFX, OFX"	R	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	ERY	S	"AZM, CLR, RXT"	S	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	ERY	R	"AZM, CLR, RXT"	R	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	TCY	S	"DOX, MNO"	S	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Moraxella catarrhalis	TCY	R	"DOX, MNO"	R	Moraxella catarrhalis	Breakpoints	12	
genus_species	is	Neisseria gonorrhoeae	BLA-S	R	"AMP, AMX"	R	Neisseria gonorrhoeae	Breakpoints	12	
genus_species	is	Neisseria gonorrhoeae	"BLA-S, PEN"	"S, S"	"AMP, AMX"	S	Neisseria gonorrhoeae	Breakpoints	12	
genus_species	is	Neisseria gonorrhoeae	"BLA-S, PEN"	"S, I"	"AMP, AMX"	I	Neisseria gonorrhoeae	Breakpoints	12	
genus_species	is	Neisseria gonorrhoeae	"BLA-S, PEN"	"S, R"	"AMP, AMX"	R	Neisseria gonorrhoeae	Breakpoints	12	
genus_species	is	Neisseria meningitidis	TCY-S	S	MNO	S	Neisseria meningitidis	Breakpoints	12	
genus_species	is	Neisseria meningitidis	TCY-S	I	MNO	I	Neisseria meningitidis	Breakpoints	12	
genus_species	is	Neisseria meningitidis	TCY-S	R	MNO	R	Neisseria meningitidis	Breakpoints	12	
genus	is	Prevotella	PEN	S	"AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP"	S	Anaerobic bacteria	Breakpoints		"x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2023"" & mo_genus(clinical_breakpoints$mo) == ""Prevotella"")]), ""AMP"", ""SAM"", ""AMX"", ""AMC"", ""PIP"", ""ETP"", ""IPM""); sort(x[x %in% betalactams()])"
genus	is	Prevotella	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints		
genus	is	Prevotella	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints		
genus	is	Prevotella	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints		
genus_species	is	Fusobacterium necrophorum	PEN	S	"AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP"	S	Anaerobic bacteria	Breakpoints		"x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2023"" & clinical_breakpoints$mo == as.mo(""Fusobacterium necrophorum""))]), ""AMP"", ""SAM"", ""AMX"", ""AMC"", ""PIP"", ""ETP"", ""IPM""); sort(x[x %in% betalactams()])"
genus_species	is	Fusobacterium necrophorum	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints		
genus_species	is	Fusobacterium necrophorum	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints		
genus_species	is	Fusobacterium necrophorum	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints		
genus_species	is	Clostridium perfringens	PEN	S	"AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP"	S	Anaerobic bacteria	Breakpoints		"x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2023"" & clinical_breakpoints$mo == as.mo(""Fusobacterium necrophorum""))]), ""AMP"", ""SAM"", ""AMX"", ""AMC"", ""PIP"", ""ETP"", ""IPM""); sort(x[x %in% betalactams()])"
genus_species	is	Clostridium perfringens	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints		
genus_species	is	Clostridium perfringens	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints		
genus_species	is	Clostridium perfringens	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints		
genus_species	is	Cutibacterium acnes	PEN	S	"AMC, AMP, AMX, CRO, CTX, ETP, IPM, MEM, PEN, PIP, SAM, TZP"	S	Anaerobic bacteria	Breakpoints		"x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == ""EUCAST 2023"" & clinical_breakpoints$mo == as.mo(""Cutibacterium acnes""))]), ""AMP"", ""SAM"", ""AMX"", ""AMC"", ""PIP"", ""ETP"", ""IPM"", ""TZP"", ""CTX"", ""CRO""); sort(x[x %in% betalactams()])"
genus_species	is	Cutibacterium acnes	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints		
genus_species	is	Cutibacterium acnes	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints		
genus_species	is	Cutibacterium acnes	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints		
genus_species	is	Cutibacterium acnes	CTX	S	CRO	S	Anaerobic bacteria	Breakpoints		
genus_species	is	Cutibacterium acnes	CTX	I	CRO	I	Anaerobic bacteria	Breakpoints		
genus_species	is	Cutibacterium acnes	CTX	R	CRO	R	Anaerobic bacteria	Breakpoints		
genus_species	is	Pasteurella multocida	PEN	S	"AMP, AMX"	S	Pasteurella multocida	Breakpoints	12	
genus_species	is	Pasteurella multocida	PEN	I	"AMP, AMX"	I	Pasteurella multocida	Breakpoints	12	
genus_species	is	Pasteurella multocida	PEN	R	"AMP, AMX"	R	Pasteurella multocida	Breakpoints	12	
genus_species	is	Pasteurella multocida	NAL-S	S	"CIP, LVX"	S	Pasteurella multocida	Breakpoints	12	
genus_species	is	Pasteurella multocida	NAL-S	R	"CIP, LVX"	R	Pasteurella multocida	Breakpoints	12	
genus_species	is	Pasteurella multocida	TCY-S	S	DOX	S	Neisseria meningitidis	Breakpoints	12	
genus_species	is	Pasteurella multocida	TCY-S	I	DOX	I	Neisseria meningitidis	Breakpoints	12	
genus_species	is	Pasteurella multocida	TCY-S	R	DOX	R	Neisseria meningitidis	Breakpoints	12	
genus_species	one_of	"Campylobacter coli, Campylobacter jejuni"	ERY	S	"AZM, CLR"	S	Campylobacter coli/jejuni	Breakpoints	12	
genus_species	one_of	"Campylobacter coli, Campylobacter jejuni"	ERY	I	"AZM, CLR"	I	Campylobacter coli/jejuni	Breakpoints	12	
genus_species	one_of	"Campylobacter coli, Campylobacter jejuni"	ERY	R	"AZM, CLR"	R	Campylobacter coli/jejuni	Breakpoints	12	
genus_species	one_of	"Campylobacter coli, Campylobacter jejuni"	TCY	S	DOX	S	Campylobacter coli/jejuni	Breakpoints	12	
genus_species	one_of	"Campylobacter coli, Campylobacter jejuni"	TCY	I	DOX	I	Campylobacter coli/jejuni	Breakpoints	12	
genus_species	one_of	"Campylobacter coli, Campylobacter jejuni"	TCY	R	DOX	R	Campylobacter coli/jejuni	Breakpoints	12	
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	I	AMX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	R	AMX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	S	CTX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	I	CTX	I	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	R	CTX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	I	MEM	S	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	PEN	R	MEM	R	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	TCY	S	DOX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	TCY	I	DOX	I	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	one_of	"Corynebacterium diphtheriae, Corynebacterium ulcerans"	TCY	R	DOX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints		
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	AMP	S	AMX	S	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	AMP	I	AMX	I	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	AMP	R	AMX	R	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	CIP	S	LVX	S	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	CIP	I	LVX	I	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	CIP	R	LVX	R	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	NOR-S	S	fluoroquinolones	S	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	NOR-S	I	fluoroquinolones	I	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	"Aerococcus sanguinicola, Aerococcus urinae"	NOR-S	R	fluoroquinolones	R	Aerococcus sanguinicola/urinae	Breakpoints	12	
genus_species	is	Kingella kingae	BLA-S	R	"PEN, AMP, AMX"	R	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	PEN	S	"AMP, AMX"	S	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	PEN	I	"AMP, AMX"	I	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	PEN	R	"AMP, AMX"	R	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	ERY	S	"AZM, CLR"	S	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	ERY	I	"AZM, CLR"	I	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	ERY	R	"AZM, CLR"	R	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints	12	
genus_species	is	Kingella kingae	TCY	R	DOX	R	Kingella kingae	Breakpoints	12	
genus	is	Vibrio	PEF-S	S	"CIP, LVX"	S	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	PEF-S	I	"CIP, LVX"	I	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	PEF-S	R	"CIP, LVX"	R	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	ERY	S	AZM	S	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	ERY	I	AZM	I	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	ERY	R	AZM	R	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	TCY-S	S	DOX	S	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	TCY-S	I	DOX	I	Vibrio spp.	Breakpoints	12	
genus	is	Vibrio	TCY-S	R	DOX	R	Vibrio spp.	Breakpoints	12	
genus	is	Bacillus	NOR-S	S	"CIP, LVX"	I	Bacillus	Breakpoints	12	
genus	is	Bacillus	NOR-S	R	"CIP, LVX"	R	Bacillus	Breakpoints	12	
genus_species	is	Burkholderia pseudomallei	TCY-S	S	DOX	I	Burkholderia pseudomallei	Breakpoints	12	
genus_species	is	Burkholderia pseudomallei	TCY-S	R	DOX	R	Burkholderia pseudomallei	Breakpoints	12	
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints	13.1	
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints	13.1	
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints	13.1	
order	is	Enterobacterales	LEX	S	CZO	I	Enterobacterales (Order)	Breakpoints	13.1	
order	is	Enterobacterales	CFR	S	CZO	I	Enterobacterales (Order)	Breakpoints	13.1	
genus	is	Salmonella	PEF-S	S	CIP	S	Enterobacterales (Order)	Breakpoints	13.1	
genus	is	Salmonella	PEF-S	I	CIP	I	Enterobacterales (Order)	Breakpoints	13.1	
genus	is	Salmonella	PEF-S	R	CIP	R	Enterobacterales (Order)	Breakpoints	13.1	
genus_species	is	Yersinia enterocolitica	TCY	S	DOX	S	Enterobacterales (Order)	Breakpoints	13.1	
genus_species	is	Yersinia enterocolitica	TCY	I	DOX	I	Enterobacterales (Order)	Breakpoints	13.1	
genus_species	is	Yersinia enterocolitica	TCY	R	DOX	R	Enterobacterales (Order)	Breakpoints	13.1	
genus_species	is	Staphylococcus aureus	FOX-S	R	penicillins	R	Staphylococcus	Breakpoints	13.1	See last sentence: Isolates that test resistant to cefoxitin are resistant to all penicillins
genus_species	is	Staphylococcus aureus	PEN, FOX-S	S, S	penicillins	S	Staphylococcus	Breakpoints	13.1	
genus_species	is	Staphylococcus aureus	PEN, FOX-S	R, S	betalactams_with_inhibitor, isoxazolylpenicillins, NAF	S	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	FOX-S	R	PEN, PHN, AMP, AMX, PIP, TIC	R	Staphylococcus	Breakpoints	13.1	
genus_species	is	Staphylococcus saprophyticus	AMP	S	AMP, SAM, AMX, AMC, PIP, TZP	S	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	FOX-S	S	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	S	Staphylococcus	Breakpoints	13.1	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus	is	Staphylococcus	FOX-S	I	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	I	Staphylococcus	Breakpoints	13.1	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus	is	Staphylococcus	FOX-S	R	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	R	Staphylococcus	Breakpoints	13.1	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	R	PEN, PHN, AMP, AMX, PIP, TIC	R	Staphylococcus	Breakpoints	13.1	
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	S	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	S	Staphylococcus	Breakpoints	13.1	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	I	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	I	Staphylococcus	Breakpoints	13.1	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	R	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	R	Staphylococcus	Breakpoints	13.1	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	is	Staphylococcus aureus	FOX-S	S	CPT	S	Staphylococcus	Breakpoints	13.1	
genus_species	is	Staphylococcus aureus	FOX-S	S	BPR	S	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	FOX-S	S	carbapenems	S	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	FOX-S	I	carbapenems	I	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	FOX-S	R	carbapenems	R	Staphylococcus	Breakpoints	13.1	
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	S	carbapenems	S	Staphylococcus	Breakpoints	13.1	Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	I	carbapenems	I	Staphylococcus	Breakpoints	13.1	Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	R	carbapenems	R	Staphylococcus	Breakpoints	13.1	Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method
genus	is	Staphylococcus	NOR-S	S	MFX	S	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	NOR-S	S	CIP, LVX	I	Staphylococcus	Breakpoints	13.1	
genus_species	is	Staphylococcus aureus	VAN	S	DAL, ORI	S	Staphylococcus	Breakpoints	13.1	
genus_species	is	Staphylococcus aureus	FOX-S, VAN	R, S	TLV	S	Staphylococcus	Breakpoints	13.1	MRSA isolates are in this file safely denoted as FOX resistant
genus	is	Staphylococcus	ERY	S	AZM, CLR, RXT	S	Staphylococcus	Breakpoints	13.1	
genus	is	Staphylococcus	TCY-S	S	DOX, MNO	S	Staphylococcus	Breakpoints	13.1	
genus	is	Enterococcus	AMP	S	AMP, SAM, AMX, AMC, PIP, TZP	S	Enterococcus	Breakpoints	13.1	
genus	is	Enterococcus	AMP	I	AMP, SAM, AMX, AMC, PIP, TZP	I	Enterococcus	Breakpoints	13.1	
genus	is	Enterococcus	AMP	R	AMP, SAM, AMX, AMC, PIP, TZP	R	Enterococcus	Breakpoints	13.1	
genus	is	Enterococcus	NOR-S	S	CIP, LVX	S	Enterococcus	Breakpoints	13.1	
genus	is	Enterococcus	NOR-S	I	CIP, LVX	I	Enterococcus	Breakpoints	13.1	
genus	is	Enterococcus	NOR-S	R	CIP, LVX	R	Enterococcus	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group C, Streptococcus Group G	PEN	S	penicillins	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group C, Streptococcus Group G	PEN	I	penicillins	I	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group C, Streptococcus Group G	PEN	R	penicillins	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	is	Streptococcus Group B	PEN	S	AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	penicillins()[!penicillins() %in% c("PHN", isoxazolylpenicillins())]
genus_species	is	Streptococcus Group B	PEN	I	AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP	I	Streptococcus groups A, B, C, G	Breakpoints	13.1	penicillins()[!penicillins() %in% c("PHN", isoxazolylpenicillins())]
genus_species	is	Streptococcus Group B	PEN	R	AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	penicillins()[!penicillins() %in% c("PHN", isoxazolylpenicillins())]
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	cephalosporins	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	I	cephalosporins	I	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	R	cephalosporins	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	carbapenems	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	I	carbapenems	I	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	R	carbapenems	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR-S	S	MFX	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR-S	S	LVX	I	Streptococcus groups A, B, C, G	Breakpoints	13.1	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR-S	R	MFX, LVX	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	VAN	S	DAL, ORI	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	S	AZM, CLR, RXT	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	R	AZM, CLR, RXT	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	TCY-S	S	DOX, MNO	S	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	TCY-S	R	DOX, MNO	R	Streptococcus groups A, B, C, G	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	OXA-S	S	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PHN, PIP, SAM, TZP	S	Streptococcus pneumoniae	Breakpoints	13.1	x <- unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2022" & clinical_breakpoints$mo == as.mo("S. pneumoniae") & clinical_breakpoints$ab != as.ab("cefaclor"))]); sort(c(x[x %in% betalactams()], "SAM", "PIP", "TZP", "PHN", "IMR", "MEV"))
genus_species	is	Streptococcus pneumoniae	PEN	S	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PHN, PIP, SAM, TZP	S	Streptococcus pneumoniae	Breakpoints	13.1	x <- unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2022" & clinical_breakpoints$mo == as.mo("S. pneumoniae") & clinical_breakpoints$ab != as.ab("cefaclor"))]); sort(c(x[x %in% betalactams()], "SAM", "PIP", "TZP", "PHN", "IMR", "MEV"))
genus_species	is	Streptococcus pneumoniae	OXA-S	S	CEC	I	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	PEN	S	CEC	I	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	OXA-S	R	PEN, PHN	R	Streptococcus pneumoniae	Breakpoints	13.1	from flowchart: when OXA < 20 or PEN > 0.06
genus_species	is	Streptococcus pneumoniae	PEN	R	PHN	R	Streptococcus pneumoniae	Breakpoints	13.1	from flowchart: when OXA < 20 or PEN > 0.06
genus_species	is	Streptococcus pneumoniae	AMP	S	AMX, AMC, SAM, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	AMP	I	AMX, AMC, SAM, PIP, TZP	I	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	AMP	R	AMX, AMC, SAM, PIP, TZP	R	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	NOR-S	S	MFX	S	Streptococcus pneumoniae	Breakpoints	13.1	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	NOR-S	S	LVX	I	Streptococcus pneumoniae	Breakpoints	13.1	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	NOR-S	R	MFX, LVX	R	Streptococcus pneumoniae	Breakpoints	13.1	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	ERY	S	AZM, CLR, RXT	S	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	ERY	R	AZM, CLR, RXT	R	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	TCY-S	S	DOX, MNO	S	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	is	Streptococcus pneumoniae	TCY-S	R	DOX, MNO	R	Streptococcus pneumoniae	Breakpoints	13.1	
genus_species	one_of	Viridans Group Streptococcus (VGS)	PEN-S	S	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PIP, SAM, TZP	S	Viridans group streptococci	Breakpoints	13.1	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	PEN-S	R	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PIP, SAM, TZP	R	Viridans group streptococci	Breakpoints	13.1	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	AMP	S	AMX, AMC, SAM, PIP, TZP	S	Viridans group streptococci	Breakpoints	13.1	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	AMP	I	AMX, AMC, SAM, PIP, TZP	I	Viridans group streptococci	Breakpoints	13.1	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	AMP	R	AMX, AMC, SAM, PIP, TZP	R	Viridans group streptococci	Breakpoints	13.1	will be expanded in eucast_rules()
genus_species	is	Haemophilus influenzae	PEN-S	S	AMC, AMP, AMX, CFM, CPD, CPT, CRO, CTB, CTX, CXM, CZT, DOR, ETP, FEP, IMR, IPM, MEM, MEV, PEN, SAM, TZP	S	Haemophilus influenzae	Breakpoints	13.1	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2022" & clinical_breakpoints$mo == as.mo("H. influenzae"))]), "IMR", "MEV"); sort(x[x %in% betalactams()])
genus_species	is	Haemophilus influenzae	PEN-S, BLA-S	R, R	AMP, AMX, PIP	R	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	AMC	S	SAM	S	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	AMC	I	SAM	I	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	AMC	R	SAM	R	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	NAL-S	S	CIP, LVX, MFX, OFX	S	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	NAL-S	I	CIP, LVX, MFX, OFX	I	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	NAL-S	R	CIP, LVX, MFX, OFX	R	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Haemophilus influenzae	TCY	R	DOX, MNO	R	Haemophilus influenzae	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	BLA-S	R	AMP, AMX, APL, APX, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CLO, CRB, CRN, DIC, EPC, FLC, HET, LEN, MEC, MET, MEZ, MTM, NAF, OXA, PEN, PHE, PHN, PIP, PME, PNM, PRB, PRC, PRP, PVM, SBC, SLT6, SRX, TAL, TEM, TIC	R	Moraxella catarrhalis	Breakpoints	13.1	penicillins()[!penicillins() %in% betalactams_with_inhibitor()]
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	NAL-S	S	CIP, LVX, MFX, OFX	S	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	NAL-S	R	CIP, LVX, MFX, OFX	R	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	ERY	S	AZM, CLR, RXT	S	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	ERY	R	AZM, CLR, RXT	R	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	TCY	S	DOX, MNO	S	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Moraxella catarrhalis	TCY	R	DOX, MNO	R	Moraxella catarrhalis	Breakpoints	13.1	
genus_species	is	Neisseria gonorrhoeae	BLA-S	R	AMP, AMX	R	Neisseria gonorrhoeae	Breakpoints	13.1	
genus_species	is	Neisseria gonorrhoeae	BLA-S, PEN	S, S	AMP, AMX	S	Neisseria gonorrhoeae	Breakpoints	13.1	
genus_species	is	Neisseria gonorrhoeae	BLA-S, PEN	S, I	AMP, AMX	I	Neisseria gonorrhoeae	Breakpoints	13.1	
genus_species	is	Neisseria gonorrhoeae	BLA-S, PEN	S, R	AMP, AMX	R	Neisseria gonorrhoeae	Breakpoints	13.1	
genus_species	is	Neisseria meningitidis	TCY-S	S	MNO	S	Neisseria meningitidis	Breakpoints	13.1	
genus_species	is	Neisseria meningitidis	TCY-S	I	MNO	I	Neisseria meningitidis	Breakpoints	13.1	
genus_species	is	Neisseria meningitidis	TCY-S	R	MNO	R	Neisseria meningitidis	Breakpoints	13.1	
genus	is	Prevotella	PEN	S	AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	13.1	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2023" & mo_genus(clinical_breakpoints$mo) == "Prevotella")]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM"); sort(x[x %in% betalactams()])
genus	is	Prevotella	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	13.1	
genus	is	Prevotella	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	13.1	
genus	is	Prevotella	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Fusobacterium necrophorum	PEN	S	AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	13.1	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2023" & clinical_breakpoints$mo == as.mo("Fusobacterium necrophorum"))]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM"); sort(x[x %in% betalactams()])
genus_species	is	Fusobacterium necrophorum	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Fusobacterium necrophorum	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Fusobacterium necrophorum	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Clostridium perfringens	PEN	S	AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	13.1	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2023" & clinical_breakpoints$mo == as.mo("Fusobacterium necrophorum"))]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM"); sort(x[x %in% betalactams()])
genus_species	is	Clostridium perfringens	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Clostridium perfringens	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Clostridium perfringens	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Cutibacterium acnes	PEN	S	AMC, AMP, AMX, CRO, CTX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	13.1	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2023" & clinical_breakpoints$mo == as.mo("Cutibacterium acnes"))]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM", "TZP", "CTX", "CRO"); sort(x[x %in% betalactams()])
genus_species	is	Cutibacterium acnes	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Cutibacterium acnes	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Cutibacterium acnes	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Cutibacterium acnes	CTX	S	CRO	S	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Cutibacterium acnes	CTX	I	CRO	I	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Cutibacterium acnes	CTX	R	CRO	R	Anaerobic bacteria	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	PEN	S	AMP, AMX	S	Pasteurella multocida	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	PEN	I	AMP, AMX	I	Pasteurella multocida	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	PEN	R	AMP, AMX	R	Pasteurella multocida	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	NAL-S	S	CIP, LVX	S	Pasteurella multocida	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	NAL-S	R	CIP, LVX	R	Pasteurella multocida	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	TCY-S	S	DOX	S	Neisseria meningitidis	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	TCY-S	I	DOX	I	Neisseria meningitidis	Breakpoints	13.1	
genus_species	is	Pasteurella multocida	TCY-S	R	DOX	R	Neisseria meningitidis	Breakpoints	13.1	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	ERY	S	AZM, CLR	S	Campylobacter coli/jejuni	Breakpoints	13.1	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	ERY	I	AZM, CLR	I	Campylobacter coli/jejuni	Breakpoints	13.1	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	ERY	R	AZM, CLR	R	Campylobacter coli/jejuni	Breakpoints	13.1	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	TCY	S	DOX	S	Campylobacter coli/jejuni	Breakpoints	13.1	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	TCY	I	DOX	I	Campylobacter coli/jejuni	Breakpoints	13.1	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	TCY	R	DOX	R	Campylobacter coli/jejuni	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	I	AMX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	R	AMX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	S	CTX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	I	CTX	I	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	R	CTX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	I	MEM	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	R	MEM	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	TCY	S	DOX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	TCY	I	DOX	I	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	TCY	R	DOX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	AMP	S	AMX	S	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	AMP	I	AMX	I	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	AMP	R	AMX	R	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	CIP	S	LVX	S	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	CIP	I	LVX	I	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	CIP	R	LVX	R	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	NOR-S	S	fluoroquinolones	S	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	NOR-S	I	fluoroquinolones	I	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	NOR-S	R	fluoroquinolones	R	Aerococcus sanguinicola/urinae	Breakpoints	13.1	
genus_species	is	Kingella kingae	BLA-S	R	PEN, AMP, AMX	R	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	PEN	S	AMP, AMX	S	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	PEN	I	AMP, AMX	I	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	PEN	R	AMP, AMX	R	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	ERY	S	AZM, CLR	S	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	ERY	I	AZM, CLR	I	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	ERY	R	AZM, CLR	R	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints	13.1	
genus_species	is	Kingella kingae	TCY	R	DOX	R	Kingella kingae	Breakpoints	13.1	
genus	is	Vibrio	PEF-S	S	CIP, LVX	S	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	PEF-S	I	CIP, LVX	I	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	PEF-S	R	CIP, LVX	R	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	ERY	S	AZM	S	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	ERY	I	AZM	I	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	ERY	R	AZM	R	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	TCY-S	S	DOX	S	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	TCY-S	I	DOX	I	Vibrio spp.	Breakpoints	13.1	
genus	is	Vibrio	TCY-S	R	DOX	R	Vibrio spp.	Breakpoints	13.1	
genus	is	Bacillus	NOR-S	S	CIP, LVX	I	Bacillus	Breakpoints	13.1	
genus	is	Bacillus	NOR-S	R	CIP, LVX	R	Bacillus	Breakpoints	13.1	
genus_species	is	Burkholderia pseudomallei	TCY-S	S	DOX	I	Burkholderia pseudomallei	Breakpoints	13.1	
genus_species	is	Burkholderia pseudomallei	TCY-S	R	DOX	R	Burkholderia pseudomallei	Breakpoints	13.1	
order	is	Enterobacterales	AMP	S	AMX	S	Enterobacterales (Order)	Breakpoints	14	
order	is	Enterobacterales	AMP	I	AMX	I	Enterobacterales (Order)	Breakpoints	14	
order	is	Enterobacterales	AMP	R	AMX	R	Enterobacterales (Order)	Breakpoints	14	
order	is	Enterobacterales	LEX	S	CZO	I	Enterobacterales (Order)	Breakpoints	14	
order	is	Enterobacterales	CFR	S	CZO	I	Enterobacterales (Order)	Breakpoints	14	
genus	is	Salmonella	PEF-S	S	CIP	S	Enterobacterales (Order)	Breakpoints	14	
genus	is	Salmonella	PEF-S	I	CIP	I	Enterobacterales (Order)	Breakpoints	14	
genus	is	Salmonella	PEF-S	R	CIP	R	Enterobacterales (Order)	Breakpoints	14	
genus_species	is	Yersinia enterocolitica	TCY	S	DOX	S	Enterobacterales (Order)	Breakpoints	14	
genus_species	is	Yersinia enterocolitica	TCY	I	DOX	I	Enterobacterales (Order)	Breakpoints	14	
genus_species	is	Yersinia enterocolitica	TCY	R	DOX	R	Enterobacterales (Order)	Breakpoints	14	
genus_species	is	Staphylococcus aureus	FOX-S	R	penicillins	R	Staphylococcus	Breakpoints	14	See last sentence: Isolates that test resistant to cefoxitin are resistant to all penicillins
genus_species	is	Staphylococcus aureus	PEN, FOX-S	S, S	penicillins	S	Staphylococcus	Breakpoints	14	
genus_species	is	Staphylococcus aureus	PEN, FOX-S	R, S	betalactams_with_inhibitor, isoxazolylpenicillins, NAF	S	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	FOX-S	R	PEN, PHN, AMP, AMX, PIP, TIC	R	Staphylococcus	Breakpoints	14	
genus_species	is	Staphylococcus saprophyticus	AMP	S	AMP, SAM, AMX, AMC, PIP, TZP	S	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	FOX-S	S	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	S	Staphylococcus	Breakpoints	14	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus	is	Staphylococcus	FOX-S	I	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	I	Staphylococcus	Breakpoints	14	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus	is	Staphylococcus	FOX-S	R	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	R	Staphylococcus	Breakpoints	14	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	R	PEN, PHN, AMP, AMX, PIP, TIC	R	Staphylococcus	Breakpoints	14	
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	S	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	S	Staphylococcus	Breakpoints	14	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	I	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	I	Staphylococcus	Breakpoints	14	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	R	BPR, CAC, CAT, CCL, CCP, CCV, CCX, CDC, CDR, CEB, CEC, CED, CEM, CEP, CEQ, CFA, CFM, CFM1, CFP, CFR, CFS, CFZ, CHE, CID, CMX, CMZ, CND, CPA, CPC, CPD, CPI, CPL, CPM, CPO, CPR, CPT, CPX, CRD, CRO, CSE, CSL, CSU, CTC, CTF, CTL, CTS, CTT, CTX, CTZ, CXA, CXM, CZD, CZL, CZO, CZP, CZX, DIT, DIX, DIZ, FDC, FEP, FNC, FOV, FOX, FOX-S, FPT, FPZ, HAP, LOR, LTM, MAN, RID, TIO, ZOP	R	Staphylococcus	Breakpoints	14	sort(c(cephalosporins()[!cephalosporins() %in% as.ab(c("cefalexin", "ceftazidim", "ceftazidim/avibactam", "ceftibuten", "ceftolozan/tazobactam"))]))
genus_species	is	Staphylococcus aureus	FOX-S	S	CPT	S	Staphylococcus	Breakpoints	14	
genus_species	is	Staphylococcus aureus	FOX-S	S	BPR	S	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	FOX-S	S	carbapenems	S	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	FOX-S	I	carbapenems	I	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	FOX-S	R	carbapenems	R	Staphylococcus	Breakpoints	14	
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	S	carbapenems	S	Staphylococcus	Breakpoints	14	Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	I	carbapenems	I	Staphylococcus	Breakpoints	14	Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method
genus_species	one_of	Staphylococcus pseudintermedius, Staphylococcus schleiferi, Staphylococcus coagulans	OXA-S	R	carbapenems	R	Staphylococcus	Breakpoints	14	Not explicitly mentioned in guidelines in this section, but previous section about these 3 species do mention OXA as preferred method
genus	is	Staphylococcus	NOR-S	S	MFX	S	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	NOR-S	S	CIP, LVX	I	Staphylococcus	Breakpoints	14	
genus_species	is	Staphylococcus coagulase-negative	VAN, TEC	S, S	DAL	S	Staphylococcus	Breakpoints	14	
genus_species	is	Staphylococcus aureus	VAN	S	DAL, ORI	S	Staphylococcus	Breakpoints	14	
genus_species	is	Staphylococcus aureus	FOX-S, VAN	R, S	TLV	S	Staphylococcus	Breakpoints	14	MRSA isolates are in this file safely denoted as FOX resistant
genus	is	Staphylococcus	ERY	S	AZM, CLR, RXT	S	Staphylococcus	Breakpoints	14	
genus	is	Staphylococcus	TCY-S	S	DOX, MNO	S	Staphylococcus	Breakpoints	14	
genus	is	Enterococcus	AMP	S	AMP, SAM, AMX, AMC, PIP, TZP	S	Enterococcus	Breakpoints	14	
genus	is	Enterococcus	AMP	I	AMP, SAM, AMX, AMC, PIP, TZP	I	Enterococcus	Breakpoints	14	
genus	is	Enterococcus	AMP	R	AMP, SAM, AMX, AMC, PIP, TZP	R	Enterococcus	Breakpoints	14	
genus	is	Enterococcus	NOR-S	S	CIP, LVX	S	Enterococcus	Breakpoints	14	
genus	is	Enterococcus	NOR-S	I	CIP, LVX	I	Enterococcus	Breakpoints	14	
genus	is	Enterococcus	NOR-S	R	CIP, LVX	R	Enterococcus	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group C, Streptococcus Group G	PEN	S	penicillins	S	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group C, Streptococcus Group G	PEN	I	penicillins	I	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group C, Streptococcus Group G	PEN	R	penicillins	R	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	is	Streptococcus Group B	PEN	S	AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP	S	Streptococcus groups A, B, C, G	Breakpoints	14	penicillins()[!penicillins() %in% c("PHN", isoxazolylpenicillins())]
genus_species	is	Streptococcus Group B	PEN	I	AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP	I	Streptococcus groups A, B, C, G	Breakpoints	14	penicillins()[!penicillins() %in% c("PHN", isoxazolylpenicillins())]
genus_species	is	Streptococcus Group B	PEN	R	AMC, AMP, AMX, APL, APX, AXS, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CRB, CRN, EPC, HET, LEN, MEC, MEZ, MSU, MTM, NAF, PEN, PHE, PIP, PIS, PME, PNM, PNO, PRB, PRC, PRP, PSU, PVM, SAM, SBC, SLT6, SRX, TAL, TCC, TEM, TIC, TZP	R	Streptococcus groups A, B, C, G	Breakpoints	14	penicillins()[!penicillins() %in% c("PHN", isoxazolylpenicillins())]
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	cephalosporins	S	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	I	cephalosporins	I	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	R	cephalosporins	R	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	carbapenems	S	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	I	carbapenems	I	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	R	carbapenems	R	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR-S	S	MFX	S	Streptococcus groups A, B, C, G	Breakpoints	14	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR-S	S	LVX	I	Streptococcus groups A, B, C, G	Breakpoints	14	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR-S	R	MFX, LVX	R	Streptococcus groups A, B, C, G	Breakpoints	14	does not explicitly state that it is for other fluoroquinolones
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	VAN	S	DAL, ORI	S	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	S	AZM, CLR, RXT	S	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	ERY	R	AZM, CLR, RXT	R	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	TCY-S	S	DOX, MNO	S	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	TCY-S	R	DOX, MNO	R	Streptococcus groups A, B, C, G	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	OXA-S	S	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PHN, PIP, SAM, TZP	S	Streptococcus pneumoniae	Breakpoints	14	x <- unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2022" & clinical_breakpoints$mo == as.mo("S. pneumoniae") & clinical_breakpoints$ab != as.ab("cefaclor"))]); sort(c(x[x %in% betalactams()], "SAM", "PIP", "TZP", "PHN", "IMR", "MEV"))
genus_species	is	Streptococcus pneumoniae	PEN	S	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PHN, PIP, SAM, TZP	S	Streptococcus pneumoniae	Breakpoints	14	x <- unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2022" & clinical_breakpoints$mo == as.mo("S. pneumoniae") & clinical_breakpoints$ab != as.ab("cefaclor"))]); sort(c(x[x %in% betalactams()], "SAM", "PIP", "TZP", "PHN", "IMR", "MEV"))
genus_species	is	Streptococcus pneumoniae	OXA-S	S	CEC	I	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	PEN	S	CEC	I	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	OXA-S	R	PEN, PHN	R	Streptococcus pneumoniae	Breakpoints	14	from flowchart: when OXA < 20 or PEN > 0.06
genus_species	is	Streptococcus pneumoniae	PEN	R	PHN	R	Streptococcus pneumoniae	Breakpoints	14	from flowchart: when OXA < 20 or PEN > 0.06
genus_species	is	Streptococcus pneumoniae	AMP	S	AMX, AMC, SAM, PIP, TZP	S	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	AMP	I	AMX, AMC, SAM, PIP, TZP	I	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	AMP	R	AMX, AMC, SAM, PIP, TZP	R	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	NOR-S	S	MFX	S	Streptococcus pneumoniae	Breakpoints	14	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	NOR-S	S	LVX	I	Streptococcus pneumoniae	Breakpoints	14	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	NOR-S	R	MFX, LVX	R	Streptococcus pneumoniae	Breakpoints	14	does not explicitly state that it is for other fluoroquinolones
genus_species	is	Streptococcus pneumoniae	ERY	S	AZM, CLR, RXT	S	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	ERY	R	AZM, CLR, RXT	R	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	TCY-S	S	DOX, MNO	S	Streptococcus pneumoniae	Breakpoints	14	
genus_species	is	Streptococcus pneumoniae	TCY-S	R	DOX, MNO	R	Streptococcus pneumoniae	Breakpoints	14	
genus_species	one_of	Viridans Group Streptococcus (VGS)	PEN-S	S	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PIP, SAM, TZP	S	Viridans group streptococci	Breakpoints	14	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	PEN-S	R	AMC, AMP, AMX, CPD, CPT, CRO, CTX, CXM, DOR, ETP, FEP, IMR, IPM, MEM, MEV, OXA, PEN, PIP, SAM, TZP	R	Viridans group streptococci	Breakpoints	14	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	AMP	S	AMX, AMC, SAM, PIP, TZP	S	Viridans group streptococci	Breakpoints	14	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	AMP	I	AMX, AMC, SAM, PIP, TZP	I	Viridans group streptococci	Breakpoints	14	will be expanded in eucast_rules()
genus_species	one_of	Viridans Group Streptococcus (VGS)	AMP	R	AMX, AMC, SAM, PIP, TZP	R	Viridans group streptococci	Breakpoints	14	will be expanded in eucast_rules()
genus_species	is	Haemophilus influenzae	PEN-S	S	AMC, AMP, AMX, CFM, CPD, CPT, CRO, CTB, CTX, CXM, CZT, DOR, ETP, FEP, IMR, IPM, MEM, MEV, PEN, SAM, TZP	S	Haemophilus influenzae	Breakpoints	14	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2022" & clinical_breakpoints$mo == as.mo("H. influenzae"))]), "IMR", "MEV"); sort(x[x %in% betalactams()])
genus_species	is	Haemophilus influenzae	PEN-S, BLA-S	R, R	AMP, AMX, PIP	R	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	AMC	S	SAM	S	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	AMC	I	SAM	I	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	AMC	R	SAM	R	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	NAL-S	S	CIP, LVX, MFX, OFX	S	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	NAL-S	I	CIP, LVX, MFX, OFX	I	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	NAL-S	R	CIP, LVX, MFX, OFX	R	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Haemophilus influenzae	TCY	R	DOX, MNO	R	Haemophilus influenzae	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	BLA-S	R	AMP, AMX, APL, APX, AZD, AZL, BAM, BNB, BNP, CIC, CLM, CLO, CRB, CRN, DIC, EPC, FLC, HET, LEN, MEC, MET, MEZ, MTM, NAF, OXA, PEN, PHE, PHN, PIP, PME, PNM, PRB, PRC, PRP, PVM, SBC, SLT6, SRX, TAL, TEM, TIC	R	Moraxella catarrhalis	Breakpoints	14	penicillins()[!penicillins() %in% betalactams_with_inhibitor()]
genus_species	is	Moraxella catarrhalis	AMC	S	TZP	S	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	AMC	I	TZP	I	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	AMC	R	TZP	R	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	NAL-S	S	CIP, LVX, MFX, OFX	S	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	NAL-S	R	CIP, LVX, MFX, OFX	R	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	ERY	S	AZM, CLR, RXT	S	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	ERY	R	AZM, CLR, RXT	R	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	TCY	S	DOX, MNO	S	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Moraxella catarrhalis	TCY	R	DOX, MNO	R	Moraxella catarrhalis	Breakpoints	14	
genus_species	is	Neisseria gonorrhoeae	BLA-S	R	AMP, AMX	R	Neisseria gonorrhoeae	Breakpoints	14	
genus_species	is	Neisseria gonorrhoeae	BLA-S, PEN	S, S	AMP, AMX	S	Neisseria gonorrhoeae	Breakpoints	14	
genus_species	is	Neisseria gonorrhoeae	BLA-S, PEN	S, I	AMP, AMX	I	Neisseria gonorrhoeae	Breakpoints	14	
genus_species	is	Neisseria gonorrhoeae	BLA-S, PEN	S, R	AMP, AMX	R	Neisseria gonorrhoeae	Breakpoints	14	
genus_species	is	Neisseria meningitidis	TCY-S	S	MNO	S	Neisseria meningitidis	Breakpoints	14	
genus_species	is	Neisseria meningitidis	TCY-S	I	MNO	I	Neisseria meningitidis	Breakpoints	14	
genus_species	is	Neisseria meningitidis	TCY-S	R	MNO	R	Neisseria meningitidis	Breakpoints	14	
genus	is	Prevotella	PEN	S	AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	14	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2024" & mo_genus(clinical_breakpoints$mo) == "Prevotella")]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM"); sort(x[x %in% betalactams()])
genus	is	Prevotella	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	14	
genus	is	Prevotella	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	14	
genus	is	Prevotella	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Fusobacterium necrophorum	PEN	S	AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	14	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2024" & clinical_breakpoints$mo == as.mo("Fusobacterium necrophorum"))]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM"); sort(x[x %in% betalactams()])
genus_species	is	Fusobacterium necrophorum	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Fusobacterium necrophorum	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Fusobacterium necrophorum	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Clostridium perfringens	PEN	S	AMC, AMP, AMX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	14	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2024" & clinical_breakpoints$mo == as.mo("Fusobacterium necrophorum"))]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM"); sort(x[x %in% betalactams()])
genus_species	is	Clostridium perfringens	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Clostridium perfringens	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Clostridium perfringens	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Cutibacterium acnes	PEN	S	AMC, AMP, AMX, CRO, CTX, ETP, IPM, MEM, PEN, PIP, SAM, TZP	S	Anaerobic bacteria	Breakpoints	14	x <- c(unique(clinical_breakpoints$ab[which(clinical_breakpoints$guideline == "EUCAST 2024" & clinical_breakpoints$mo == as.mo("Cutibacterium acnes"))]), "AMP", "SAM", "AMX", "AMC", "PIP", "ETP", "IPM", "TZP", "CTX", "CRO"); sort(x[x %in% betalactams()])
genus_species	is	Cutibacterium acnes	AMP	S	AMX	S	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Cutibacterium acnes	AMP	I	AMX	I	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Cutibacterium acnes	AMP	R	AMX	R	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Cutibacterium acnes	CTX	S	CRO	S	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Cutibacterium acnes	CTX	I	CRO	I	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Cutibacterium acnes	CTX	R	CRO	R	Anaerobic bacteria	Breakpoints	14	
genus_species	is	Pasteurella multocida	PEN	S	AMP, AMX	S	Pasteurella multocida	Breakpoints	14	
genus_species	is	Pasteurella multocida	PEN	I	AMP, AMX	I	Pasteurella multocida	Breakpoints	14	
genus_species	is	Pasteurella multocida	PEN	R	AMP, AMX	R	Pasteurella multocida	Breakpoints	14	
genus_species	is	Pasteurella multocida	NAL-S	S	CIP, LVX	S	Pasteurella multocida	Breakpoints	14	
genus_species	is	Pasteurella multocida	NAL-S	R	CIP, LVX	R	Pasteurella multocida	Breakpoints	14	
genus_species	is	Pasteurella multocida	TCY-S	S	DOX	S	Neisseria meningitidis	Breakpoints	14	
genus_species	is	Pasteurella multocida	TCY-S	I	DOX	I	Neisseria meningitidis	Breakpoints	14	
genus_species	is	Pasteurella multocida	TCY-S	R	DOX	R	Neisseria meningitidis	Breakpoints	14	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	ERY	S	AZM, CLR	S	Campylobacter coli/jejuni	Breakpoints	14	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	ERY	I	AZM, CLR	I	Campylobacter coli/jejuni	Breakpoints	14	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	ERY	R	AZM, CLR	R	Campylobacter coli/jejuni	Breakpoints	14	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	TCY	S	DOX	S	Campylobacter coli/jejuni	Breakpoints	14	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	TCY	I	DOX	I	Campylobacter coli/jejuni	Breakpoints	14	
genus_species	one_of	Campylobacter coli, Campylobacter jejuni	TCY	R	DOX	R	Campylobacter coli/jejuni	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	I	AMX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	R	AMX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	I	CTX	I	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	R	CTX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	I	MEM	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	PEN	R	MEM	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	TCY	S	DOX	S	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	one_of	Corynebacterium diphtheriae, Corynebacterium ulcerans	TCY	R	DOX	R	Corynebacterium diphtheriae/ulcerans	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	AMP	S	AMX	S	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	AMP	I	AMX	I	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	AMP	R	AMX	R	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	CIP	S	LVX	S	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	CIP	I	LVX	I	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	CIP	R	LVX	R	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	NOR-S	S	fluoroquinolones	S	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	NOR-S	I	fluoroquinolones	I	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Aerococcus sanguinicola, Aerococcus urinae	NOR-S	R	fluoroquinolones	R	Aerococcus sanguinicola/urinae	Breakpoints	14	
genus_species	is	Kingella kingae	BLA-S	R	PEN, AMP, AMX	R	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	PEN	S	AMP, AMX	S	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	PEN	I	AMP, AMX	I	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	PEN	R	AMP, AMX	R	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	ERY	S	AZM, CLR	S	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	ERY	I	AZM, CLR	I	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	ERY	R	AZM, CLR	R	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	TCY	S	DOX	S	Kingella kingae	Breakpoints	14	
genus_species	is	Kingella kingae	TCY	R	DOX	R	Kingella kingae	Breakpoints	14	
genus	is	Vibrio	PEF-S	S	CIP, LVX	S	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	PEF-S	I	CIP, LVX	I	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	PEF-S	R	CIP, LVX	R	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	ERY	S	AZM	S	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	ERY	I	AZM	I	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	ERY	R	AZM	R	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	TCY-S	S	DOX	S	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	TCY-S	I	DOX	I	Vibrio spp.	Breakpoints	14	
genus	is	Vibrio	TCY-S	R	DOX	R	Vibrio spp.	Breakpoints	14	
genus	is	Bacillus	NOR-S	S	CIP, LVX	I	Bacillus	Breakpoints	14	
genus	is	Bacillus	NOR-S	R	CIP, LVX	R	Bacillus	Breakpoints	14	
genus_species	is	Bacillus anthracis	PEN	I	AMX	S	Bacillus anthracis	Breakpoints	14	
genus_species	is	Bacillus anthracis	PEN	R	AMX	R	Bacillus anthracis	Breakpoints	14	
genus_species	is	Bacillus anthracis	TCY-S	S	DOX	S	Bacillus anthracis	Breakpoints	14	
genus_species	is	Bacillus anthracis	TCY-S	R	DOX	R	Bacillus anthracis	Breakpoints	14	
genus_species	is	Brucella melitensis	TCY-S	S	DOX	S	Brucella melitensis	Breakpoints	14	
genus_species	is	Brucella melitensis	TCY-S	R	DOX	R	Brucella melitensis	Breakpoints	14	
genus_species	is	Burkholderia pseudomallei	TCY-S	S	DOX	I	Burkholderia pseudomallei	Breakpoints	14	
genus_species	is	Burkholderia pseudomallei	TCY-S	R	DOX	R	Burkholderia pseudomallei	Breakpoints	14	
order	is	Enterobacterales			PEN, glycopeptides, lipoglycopeptides, FUS, macrolides, lincosamides, streptogramins, RIF, oxazolidinones	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	one_of	Citrobacter koseri, Citrobacter amalonaticus			AMP, AMX, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Citrobacter freundii			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	one_of	Enterobacter cloacae complex			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Escherichia hermannii			AMP, AMX, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Hafnia alvei			AMP, AMX, PLB, COL	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Klebsiella aerogenes 			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	one_of	Klebsiella pneumoniae complex			AMX, AMP, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Klebsiella oxytoca			AMX, AMP, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Leclercia adecarboxylata			FOS	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Morganella morganii 			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, tetracyclines, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Plesiomonas shigelloides 			AMX, AMP, SAM	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Proteus mirabilis 			tetracyclines, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Proteus penneri 			AMP, AMX, CZO, CEP, LEX, CFR, CXM, tetracyclines, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Proteus vulgaris 			AMP, AMX, CZO, CEP, LEX, CFR, CXM, tetracyclines, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Providencia rettgeri 			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, tetracyclines, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Providencia stuartii			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, tetracyclines, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus	is	Raoultella			AMP, AMX, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Serratia marcescens			AMP, AMX, AMC, SAM, CZO, CEP, LEX, CFR, FOX, CXM, PLB, COL, NIT	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Yersinia enterocolitica			AMP, AMX, AMC, SAM, TIC, CZO, CEP, LEX, CFR, FOX	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Yersinia pseudotuberculosis			PLB, COL	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Aeromonas hydrophila			AMP, AMX, SAM	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Aeromonas veronii			AMP, AMX, SAM, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Aeromonas dhakensis			AMP, AMX, SAM, FOX	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Aeromonas caviae			AMP, AMX, SAM	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus_species	is	Aeromonas jandaei			AMP, AMX, SAM, TIC	R	Table 1: Expected resistant phenotype in Enterobacterales and Aeromonas spp.	Expected phenotypes	1.2	
genus	one_of	Acinetobacter, Achromobacter, Burkholderia, Elizabethkingia, Elizabethkingia, Ochrobactrum, Pseudomonas, Stenotrophomonas, Chryseobacterium			PEN, cephalosporins_1st, cephalosporins_2nd, glycopeptides, lipoglycopeptides, FUS, macrolides, lincosamides, streptogramins, RIF, oxazolidinones	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	one_of	Acinetobacter baumannii, Acinetobacter pittii, Acinetobacter nosocomialis			AMP, AMX, AMC, CTX, CRO, ATM, ETP, TMP, FOS, TCY, DOX	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Achromobacter xylosoxidans			AMP, AMX, CTX, CRO, ATM, ETP	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	one_of	Burkholderia cepacia complex			AMP, AMX, AMC, SAM, TIC, TCC, PIP, TZP, CTX, CRO, ATM, ETP, CIP, CHL, aminoglycosides, TMP, FOS, PLB, COL	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Elizabethkingia meningoseptica			AMP, AMX, AMC, SAM, TIC, TCC, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM, PLB, COL	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Elizabethkingia anophelis			AMP, AMX, AMC, SAM, TIC, TCC, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Ochrobactrum anthropi			AMP, AMX, AMC, SAM, TIC, TCC, CTX, CRO, CAZ, FEP, ATM, ETP	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Pseudomonas aeruginosa			AMP, AMX, AMC, SAM, CTX, CRO, ETP, CHL, TMP, KAN, NEO, tetracyclines, TGC	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Stenotrophomonas maltophilia			AMP, AMX, AMC, SAM, TIC, PIP, TZP, CTX, CRO, ATM, ETP, IPM, MEM, aminoglycosides, TMP, FOS, TCY	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus	is	Chryseobacterium			AMP, AMX, AMC, SAM, TIC, TCC, CTX, CRO, CAZ, ATM, ETP, IPM, MEM, aminoglycosides, PLB, COL	R	Table 2: Expected resistant phenotype in non-fermentative gram-negative bacteria	Expected phenotypes	1.2	
genus	one_of	Haemophilus, Moraxella, Neisseria, Campylobacter			glycopeptides, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Expected resistant phenotype in other gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Haemophilus influenzae			FUS, streptogramins	R	Table 3: Expected resistant phenotype in other gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Moraxella catarrhalis			TMP	R	Table 3: Expected resistant phenotype in other gram-negative bacteria	Expected phenotypes	1.2	
genus	is	Neisseria			TMP	R	Table 3: Expected resistant phenotype in other gram-negative bacteria	Expected phenotypes	1.2	
genus_species	is	Campylobacter fetus			FUS, streptogramins, TMP, NAL	R	Table 3: Expected resistant phenotype in other gram-negative bacteria	Expected phenotypes	1.2	
genus_species	one_of	Campylobacter jejuni, Campylobacter coli 			FUS, streptogramins, TMP	R	Table 3: Expected resistant phenotype in other gram-negative bacteria	Expected phenotypes	1.2	
gramstain	is	Gram-positive			ATM, TEM, PLB, COL, NAL	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Staphylococcus saprophyticus			FUS, CAZ, FOS, NOV	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Staphylococcus cohnii			CAZ, NOV	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Staphylococcus xylosus			CAZ, NOV	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Staphylococcus capitis			CAZ, FOS	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	one_of	Coagulase-negative Staphylococcus (CoNS), Staphylococcus aureus			CAZ	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus	is	Streptococcus			FUS, CAZ, aminoglycosides	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Enterococcus faecalis			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, sulfonamides	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	one_of	Enterococcus gallinarum, Enterococcus casseliflavus			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, sulfonamides	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Enterococcus faecium			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, sulfonamides	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus	is	Corynebacterium			FOS	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Listeria monocytogenes			CAZ, cephalosporins_except_CAZ	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus	one_of	Leuconostoc, Pediococcus			VAN, FOS	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	is	Lactobacillus casei			VAN, FOS	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
fullname	is	Lactobacillus casei rhamnosus			VAN, FOS	R	Table 4: Expected resistant phenotype in gram-positive bacteria	Expected phenotypes	1.2	
genus_species	one_of	Clostridium ramosum, Clostridium innocuum			VAN	R	Table 5: Expected resistant phenotype in anaerobes	Expected phenotypes	1.2	
order	is	Enterobacterales			PEN, glycopeptides_except_lipo, FUS, macrolides, LIN, streptogramins, RIF, DAP, LNZ	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
fullname	like	^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
fullname	like	^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Enterobacter cloacae			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Klebsiella aerogenes			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	originally Enterobacter aerogenes, but was renamed to Klebsiella aerogenes
genus_species	is	Escherichia hermannii			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Hafnia alvei			aminopenicillins, AMC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus	is	Klebsiella			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Morganella morganii			aminopenicillins, AMC, CZO, DOX, MNO, TCY, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Proteus mirabilis			DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Proteus penneri			aminopenicillins, CZO, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Proteus vulgaris			aminopenicillins, CZO, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Providencia rettgeri			aminopenicillins, AMC, CZO, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Providencia stuartii			aminopenicillins, AMC, CZO, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus	is	Raoultella			aminopenicillins, TIC	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Serratia marcescens			aminopenicillins, AMC, CZO, FOX, CXM, DOX, TCY, polymyxins, NIT	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Yersinia enterocolitica			aminopenicillins, AMC, TIC, CZO, FOX	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus_species	is	Yersinia pseudotuberculosis			PLB, COL	R	Table 01: Intrinsic resistance in Enterobacterales (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus	one_of	Achromobacter, Acinetobacter, Alcaligenes, Bordetella, Burkholderia, Elizabethkingia, Flavobacterium, Ochrobactrum, Pseudomonas, Stenotrophomonas			PEN, FOX, CXM, glycopeptides_except_lipo, FUS, macrolides, LIN, streptogramins, RIF, DAP, LNZ	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Acinetobacter baumannii			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Acinetobacter pittii			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Acinetobacter nosocomialis			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Acinetobacter calcoaceticus			aminopenicillins, AMC, CZO, CTX, CRO, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Achromobacter xylosoxidans			aminopenicillins, CZO, CTX, CRO, ETP	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
fullname	like	^Burkholderia (ambifaria|anthina|arboris|cepacia|cenocepacia|contaminans|diffusa|dolosa|lata|latens|metallica|multivorans|paludis|pseudomultivorans|pyrrocinia|pseudomultivorans|seminalis|stabilis|stagnalis|territorii|ubonensis|vietnamiensis)			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, ATM, ETP, CIP, CHL, aminoglycosides, TMP, FOS, polymyxins	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Elizabethkingia meningoseptica			aminopenicillins, AMC, TIC, CZO, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM, polymyxins	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Brucella anthropi			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, CAZ, FEP, ATM, ETP	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Pseudomonas aeruginosa			aminopenicillins, AMC, CZO, CTX, CRO, ETP, CHL, KAN, NEO, TMP, SXT, DOX, MNO, TCY, TGC	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Stenotrophomonas maltophilia			aminopenicillins, AMC, TIC, PIP, TZP, CZO, CTX, CRO, ATM, ETP, IPM, MEM, aminoglycosides, TMP, FOS, TCY	R	Table 02: Intrinsic resistance in non-fermentative Gram-negative bacteria	Expert Rules	3.1	
genus	one_of	Haemophilus, Moraxella, Neisseria, Campylobacter			glycopeptides_except_lipo, LIN, DAP, LNZ	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Haemophilus influenzae			FUS, streptogramins	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Moraxella catarrhalis			TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
genus	is	Neisseria			TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Campylobacter fetus			FUS, streptogramins, TMP, NAL	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Campylobacter jejuni			FUS, streptogramins, TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
genus_species	is	Campylobacter coli			FUS, streptogramins, TMP	R	Table 03: Intrinsic resistance in other Gram-negative bacteria	Expert Rules	3.1	
gramstain	is	Gram-positive			ATM, polymyxins, NAL	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus saprophyticus			FUS, CAZ, FOS, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus cohnii			CAZ, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus xylosus			CAZ, NOV	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus capitis			CAZ, FOS	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus aureus			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus epidermidis			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus coagulase-negative			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus hominis			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus haemolyticus			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus intermedius			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Staphylococcus pseudintermedius			CAZ	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus	is	Streptococcus			FUS, CAZ, aminoglycosides	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Enterococcus faecalis			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Enterococcus gallinarum			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Enterococcus casseliflavus			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Enterococcus faecium			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, TMP, SXT	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus	is	Corynebacterium			FOS	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Listeria monocytogenes			cephalosporins	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus	one_of	Leuconostoc, Pediococcus			glycopeptides_except_lipo	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus	is	Lactobacillus			glycopeptides_except_lipo	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Clostridium ramosum			VAN	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	is	Clostridium innocuum			VAN	R	Table 04: Intrinsic resistance in Gram-positive bacteria	Expert Rules	3.1	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	aminopenicillins, cephalosporins_except_CAZ, carbapenems	S	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules	3.1	
genus	is	Enterococcus	AMP	R	ureidopenicillins, carbapenems	R	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules	3.1	
genus	is	Enterococcus	AMX	R	ureidopenicillins, carbapenems	R	Table 08: Interpretive rules for B-lactam agents and Gram-positive cocci	Expert Rules	3.1	
order	is	Enterobacterales	TIC, PIP	R, S	PIP	R	Table 09: Interpretive rules for B-lactam agents and Gram-negative rods (at the time: Enterobacteriaceae)	Expert Rules	3.1	
genus	like	.*	ERY	S	AZM, CLR	S	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules	3.1	
genus	like	.*	ERY	I	AZM, CLR	I	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules	3.1	
genus	like	.*	ERY	R	AZM, CLR	R	Table 11: Interpretive rules for macrolides, lincosamides, and streptogramins	Expert Rules	3.1	
genus	is	Staphylococcus	TOB	R	KAN, AMK	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules	3.1	
genus	is	Staphylococcus	GEN	R	aminoglycosides	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules	3.1	
order	is	Enterobacterales	GEN, TOB	I, S	GEN	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules	3.1	
order	is	Enterobacterales	GEN, TOB	R, I	TOB	R	Table 12: Interpretive rules for aminoglycosides	Expert Rules	3.1	
genus	is	Staphylococcus	MFX	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules	3.1	
genus_species	is	Streptococcus pneumoniae	MFX	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules	3.1	
order	is	Enterobacterales	CIP	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules	3.1	
genus_species	is	Neisseria gonorrhoeae	CIP	R	fluoroquinolones	R	Table 13: Interpretive rules for quinolones	Expert Rules	3.1	
order	is	Enterobacterales			PEN, glycopeptides_except_lipo, lipoglycopeptides, FUS, macrolides, lincosamides, streptogramins, RIF, oxazolidinones	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
fullname	like	^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
fullname	like	^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Enterobacter cloacae			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Escherichia hermannii			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Hafnia alvei			aminopenicillins, AMC, SAM, CXM, CZO, CEP, LEX, CFR, FOX, polymyxins	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Klebsiella aerogenes			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Klebsiella oxytoca			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
fullname	like	^Klebsiella( pneumoniae| quasipneumoniae| variicola)?			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Leclercia adecarboxylata			FOS	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Morganella morganii			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, DOX, MNO, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Plesiomonas shigelloides			aminopenicillins, AMC, SAM	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Proteus mirabilis			DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Proteus penneri			aminopenicillins, CZO, CEP, LEX, CFR, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Proteus vulgaris			aminopenicillins, CZO, CEP, LEX, CFR, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Providencia rettgeri			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, DOX, MNO, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Providencia stuartii			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, DOX, MNO, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus	is	Raoultella			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Serratia marcescens			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX, CXM, DOX, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Yersinia enterocolitica			aminopenicillins, AMC, SAM, TIC, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Yersinia pseudotuberculosis			polymyxins	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Aeromonas hydrophila			aminopenicillins, AMC, SAM, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Aeromonas veronii			aminopenicillins, AMC, SAM, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Aeromonas dhakensis			aminopenicillins, AMC, SAM, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Aeromonas caviae			aminopenicillins, AMC, SAM, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus_species	is	Aeromonas jandaei			aminopenicillins, AMC, SAM, TIC,  CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.2	
genus	one_of	Achromobacter, Acinetobacter, Alcaligenes, Bordetella, Burkholderia, Elizabethkingia, Flavobacterium, Ochrobactrum, Pseudomonas, Stenotrophomonas			PEN, cephalosporins_1st, cephalosporins_2nd, glycopeptides_except_lipo, lipoglycopeptides, FUS, macrolides, lincosamides, streptogramins, RIF, oxazolidinones	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	
fullname	like	^Acinetobacter (baumannii|pittii|nosocomialis)			aminopenicillins, AMC, CRO, CTX, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus	is	Acinetobacter			DOX, TCY	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Achromobacter xylosoxidans			aminopenicillins, CRO, CTX, ETP	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
fullname	like	^Burkholderia (ambifaria|anthina|arboris|cepacia|cenocepacia|contaminans|diffusa|dolosa|lata|latens|metallica|multivorans|paludis|pseudomultivorans|pyrrocinia|pseudomultivorans|seminalis|stabilis|stagnalis|territorii|ubonensis|vietnamiensis)			aminopenicillins, AMC, SAM, TIC, TCC, PIP, TZP, CRO, CTX, ATM, ETP, CIP, CHL, aminoglycosides, TMP, FOS, polymyxins	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Elizabethkingia meningoseptica			aminopenicillins, AMC, SAM, TIC, TCC, PIP, CZO, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM, polymyxins	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Brucella anthropi			aminopenicillins, AMC, SAM, TIC, TCC, PIP, TZP, CZO, CTX, CRO, CAZ, FEP, ATM, ETP	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Pseudomonas aeruginosa			aminopenicillins, AMC, SAM, CTX, CRO, ETP, CHL, KAN, NEO, TMP, DOX, MNO, TCY, TGC	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Stenotrophomonas maltophilia			aminopenicillins, AMC, SAM, TIC, PIP, TZP, CRO, CTX, ATM, ETP, IPM, MEM, aminoglycosides, TMP, FOS, TCY	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.2	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Haemophilus influenzae			FUS, streptogramins, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.2	
genus_species	is	Moraxella catarrhalis			TMP, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.2	
genus	is	Neisseria			TMP, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.2	
genus_species	is	Campylobacter fetus			FUS, streptogramins, TMP, NAL, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.2	
fullname	like	^Campylobacter (jejuni|coli)			FUS, streptogramins, TMP, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.2	
gramstain	is	Gram-positive			ATM, TEM, polymyxins, NAL	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Staphylococcus saprophyticus			FUS, CAZ, FOS, NOV	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Staphylococcus cohnii			CAZ, NOV	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Staphylococcus xylosus			CAZ, NOV	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Staphylococcus capitis			CAZ, FOS	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Staphylococcus aureus			CAZ	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Staphylococcus coagulase-negative			CAZ	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus	is	Streptococcus			FUS, CAZ, aminoglycosides	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Enterococcus faecalis			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, SDI, SUD, SDM, SLF, SLF1, SLF2, SZO, SLF3, SLF4, SMX, SLF5, SLF6, SLF7, SLF8, SLF9, SLF10, SLF11, SLF12, SUT, SLF13	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	These last ones are all true sulfonamides
genus_species	is	Enterococcus faecalis	TMP	S	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	S	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecalis	TMP	I	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	I	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecalis	TMP	R	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
fullname	like	^Enterococcus (gallinarum|casseliflavus)			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, SDI, SUD, SDM, SLF, SLF1, SLF2, SZO, SLF3, SLF4, SMX, SLF5, SLF6, SLF7, SLF8, SLF9, SLF10, SLF11, SLF12, SUT, SLF13	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	These last ones are all true sulfonamides
fullname	like	^Enterococcus (gallinarum|casseliflavus)	TMP	S	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	S	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
fullname	like	^Enterococcus (gallinarum|casseliflavus)	TMP	I	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	I	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
fullname	like	^Enterococcus (gallinarum|casseliflavus)	TMP	R	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecium			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, SDI, SUD, SDM, SLF, SLF1, SLF2, SZO, SLF3, SLF4, SMX, SLF5, SLF6, SLF7, SLF8, SLF9, SLF10, SLF11, SLF12, SUT, SLF13	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	These last ones are all true sulfonamides
genus_species	is	Enterococcus faecium	TMP	S	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	S	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecium	TMP	I	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	I	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecium	TMP	R	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	Since R to sulfonamides - TMP result is equal with combinations
genus	is	Corynebacterium			FOS	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	is	Listeria monocytogenes			CAZ, cephalosporins_except_CAZ	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus	one_of	Leuconostoc, Pediococcus			VAN, TEC	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus	is	Lactobacillus			VAN, TEC	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
fullname	like	^Clostridium (ramosum|innocuum)			VAN	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.2	
genus_species	one_of	Escherichia coli, Proteus mirabilis	AMP	R	PIP	R	Expert Rules on Enterobacterales	Expert Rules	3.2	
genus_species	one_of	Escherichia coli, Proteus mirabilis	AMP	S	PIP	S	Expert Rules on Enterobacterales	Expert Rules	3.2	
fullname	like	^(Klebsiella(?! aerogenes)|Raoultella)			PIP	R	Expert Rules on Enterobacterales	Expert Rules	3.2	
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter freundii|Serratia|Morganella morganii|Hafnia alvei|Providencia)	CXM	S	CXM, cephalosporins_2nd	R	Expert Rules on Enterobacterales	Expert Rules	3.2	
genus	one_of	Arsenophonus, Biostraticola, Brenneria, Buchnera, Budvicia, Buttiauxella, Cedecea, Citrobacter, Cosenzaea, Cronobacter, Dickeya, Edwardsiella, Enterobacillus, Enterobacter, Erwinia, Escherichia, Ewingella, Franconibacter, Gibbsiella, Hafnia, Izhakiella, Klebsiella, Kluyvera, Kosakonia, Leclercia, Lelliottia, Leminorella, Lonsdalea, Mangrovibacter, Mixta, Moellerella, Morganella, Obesumbacterium, Pantoea, Pectobacterium, Phaseolibacter, Photorhabdus, Phytobacter, Plesiomonas, Pluralibacter, Pragia, Proteus, Providencia, Pseudescherichia, Pseudocitrobacter, Rahnella, Raoultella, Rosenbergiella, Rouxiella, Saccharobacter, Samsonia, Serratia, Shigella, Shimwellia, Siccibacter, Sodalis, Tatumella, Thorsellia, Trabulsiella, Wigglesworthia, Xenorhabdus, Yersinia, Yokenella	CIP	R	fluoroquinolones	R	Expert Rules on Enterobacterales	Expert Rules	3.2	This is Enterobacterales except Salmonella spp.
fullname	like	^(Serratia|Providencia|Morganella morganii)			TGC	R	Expert Rules on Enterobacterales	Expert Rules	3.2	
genus	is	Salmonella			cephalosporins_2nd	R	Expert Rules on Salmonella	Expert Rules	3.2	
genus	is	Salmonella			aminoglycosides	R	Expert Rules on Salmonella	Expert Rules	3.2	
genus	is	Salmonella	PEF	R	CIP	R	Expert Rules on Salmonella	Expert Rules	3.2	
genus_species	is	Staphylococcus aureus	FOX	R	betalactams	R	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus_species	is	Staphylococcus aureus	FOX	S	betalactams_with_inhibitor	S	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus_species	one_of	Staphylococcus aureus, Staphylococcus lugdunensis	PEN	R	AMP, AMX, AZL, BAM, CRB, CRN, EPC, HET, MEC, MEZ, MTM, PIP, PME, PVM, SBC, TAL, TEM, TIC	R	Expert Rules on Staphylococcus	Expert Rules	3.2	all penicillins without beta-lactamse inhibitor
genus	is	Staphylococcus	ERY, CLI	S	macrolides, lincosamides	S	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	NOR	S	CIP, LVX, MFX, OFX	S	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	LVX	R	fluoroquinolones	R	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	MFX	R	fluoroquinolones	R	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	TCY	S	DOX, MNO, TGC	S	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	TCY	R	DOX, MNO	R	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	VAN	S	lipoglycopeptides	S	Expert Rules on Staphylococcus	Expert Rules	3.2	
genus	is	Staphylococcus	LNZ	S	TZD	S	Expert Rules on Staphylococcus	Expert Rules	3.2	
fullname	like	^Enterococcus (faecalis|faecium)	AMP	R	ureidopenicillins, IPM	R	Expert Rules on Enterococcus	Expert Rules	3.2	
fullname	like	^Enterococcus (faecalis|faecium)	AMX	R	ureidopenicillins, IPM	R	Expert Rules on Enterococcus	Expert Rules	3.2	
genus	is	Enterococcus	NOR	S	CIP, LVX	S	Expert Rules on Enterococcus	Expert Rules	3.2	
genus	is	Enterococcus	VAN	S	lipoglycopeptides	S	Expert Rules on Enterococcus	Expert Rules	3.2	
genus_species	is	Enterococcus faecium			CLI	R	Expert Rules on Enterococcus	Expert Rules	3.2	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	aminopenicillins, cephalosporins, carbapenems	S	Expert Rules on Streptococcus A, B, C and G	Expert Rules	3.2	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	S	LVX, MFX	S	Expert Rules on Streptococcus A, B, C and G	Expert Rules	3.2	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	R	LVX, MFX	R	Expert Rules on Streptococcus A, B, C and G	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	OXA	S	PHN, PEN, aminopenicillins, cephalosporins_except_CAZ, carbapenems	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	NOR	S	LVX, MFX	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	NOR	R	LVX, MFX	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	LVX	R	fluoroquinolones	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	MFX	R	fluoroquinolones	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	TCY	S	DOX, MNO	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	TCY	R	DOX, MNO	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	is	Streptococcus pneumoniae	VAN	S	lipoglycopeptides	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.2	
genus_species	one_of	Viridans Group Streptococcus (VGS)	PEN	S	aminopenicillins, CTX, CRO	S	Expert Rules on Viridans Group Streptococci	Expert Rules	3.2	
genus_species	is	Haemophilus influenzae	PEN	S	betalactams	S	Expert Rules on Haemophilus influenzae	Expert Rules	3.2	
genus_species	is	Haemophilus influenzae	NAL	S	fluoroquinolones	S	Expert Rules on Haemophilus influenzae	Expert Rules	3.2	
genus_species	is	Haemophilus influenzae	NAL	R	CIP, LVX, MFX	R	Expert Rules on Haemophilus influenzae	Expert Rules	3.2	
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Expert Rules on Haemophilus influenzae	Expert Rules	3.2	
genus_species	is	Haemophilus influenzae	TCY	R	DOX, MNO	R	Expert Rules on Haemophilus influenzae	Expert Rules	3.2	
genus_species	is	Moraxella catarrhalis	NAL	S	fluoroquinolones	S	Expert Rules on Moraxella catarrhalis	Expert Rules	3.2	
genus_species	is	Moraxella catarrhalis	NAL	R	fluoroquinolones	R	Expert Rules on Moraxella catarrhalis	Expert Rules	3.2	
genus	is	Campylobacter	ERY	S	CLR, AZM	S	Expert Rules on Campylobacter	Expert Rules	3.2	
genus_species	is	Campylobacter	ERY	R	CLR, AZM	R	Expert Rules on Campylobacter	Expert Rules	3.2	
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CTX	S	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.2	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CRO	S	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.2	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CAZ	S	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.2	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CTX	I	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.2	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CRO	I	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.2	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CAZ	I	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.2	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
order	is	Enterobacterales			PEN, glycopeptides_except_lipo, lipoglycopeptides, FUS, macrolides, lincosamides, streptogramins, RIF, oxazolidinones	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
fullname	like	^Citrobacter (koseri|amalonaticus|sedlakii|farmeri|rodentium)			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
fullname	like	^Citrobacter (freundii|braakii|murliniae|werkmanii|youngae)			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Enterobacter cloacae			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Escherichia hermannii			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Hafnia alvei			aminopenicillins, AMC, polymyxins	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Klebsiella aerogenes			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Klebsiella oxytoca			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
fullname	like	^Klebsiella( pneumoniae| quasipneumoniae| variicola)?			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Leclercia adecarboxylata			FOS	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Morganella morganii			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, DOX, MNO, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Plesiomonas shigelloides			aminopenicillins, AMC, SAM	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Proteus mirabilis			DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Proteus penneri			aminopenicillins, CZO, CEP, LEX, CFR, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Proteus vulgaris			aminopenicillins, CZO, CEP, LEX, CFR, CXM, DOX, MNO, TCY, TGC, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Providencia rettgeri			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, DOX, MNO, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Providencia stuartii			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, DOX, MNO, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus	is	Raoultella			aminopenicillins, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Serratia marcescens			aminopenicillins, AMC, SAM, CZO, CEP, LEX, CFR, FOX, CXM, DOX, TCY, polymyxins, NIT	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Yersinia enterocolitica			aminopenicillins, AMC, SAM, TIC, CZO, CEP, LEX, CFR, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Yersinia pseudotuberculosis			polymyxins	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Aeromonas hydrophila			aminopenicillins, SAM	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Aeromonas veronii			aminopenicillins, SAM, TIC	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Aeromonas dhakensis			aminopenicillins, SAM, FOX	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus_species	is	Aeromonas caviae			aminopenicillins, SAM	R	Table 1: Intrinsic resistance in Enterobacterales and Aeromonas spp.	Expert Rules	3.3	
genus	one_of	Achromobacter, Acinetobacter, Alcaligenes, Bordetella, Burkholderia, Elizabethkingia, Flavobacterium, Ochrobactrum, Pseudomonas, Stenotrophomonas			PEN, cephalosporins_1st, cephalosporins_2nd, glycopeptides_except_lipo, lipoglycopeptides, FUS, macrolides, lincosamides, streptogramins, RIF, oxazolidinones	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	
fullname	like	^Acinetobacter (baumannii|pittii|nosocomialis)			aminopenicillins, AMC, CRO, CTX, ATM, ETP, TMP, FOS, DOX, TCY	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus	is	Acinetobacter			DOX, TCY	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Achromobacter xylosoxidans			aminopenicillins, CRO, CTX, ETP, ATM	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
fullname	like	^Burkholderia (ambifaria|anthina|arboris|cepacia|cenocepacia|contaminans|diffusa|dolosa|lata|latens|metallica|multivorans|paludis|pseudomultivorans|pyrrocinia|pseudomultivorans|seminalis|stabilis|stagnalis|territorii|ubonensis|vietnamiensis)			aminopenicillins, AMC, SAM, TIC, TCC, PIP, TZP, CRO, CTX, ATM, ETP, CIP, CHL, aminoglycosides, TMP, FOS, polymyxins	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Elizabethkingia meningoseptica			aminopenicillins, AMC, SAM, TIC, TCC, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM, polymyxins	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Elizabethkingia anophelis			aminopenicillins, AMC, SAM, TIC, TCC, CTX, CRO, CAZ, FEP, ATM, ETP, IPM, MEM	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Brucella anthropi			aminopenicillins, AMC, SAM, TIC, TCC, PIP, TZP, CZO, CTX, CRO, CAZ, FEP, ATM, ETP	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Pseudomonas aeruginosa			aminopenicillins, AMC, SAM, CTX, CRO, ETP, CHL, KAN, NEO, TMP, DOX, MNO, TCY, TGC	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Stenotrophomonas maltophilia			aminopenicillins, AMC, SAM, TIC, PIP, TZP, CRO, CTX, ATM, ETP, IPM, MEM, aminoglycosides, TMP, FOS, TCY	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus	is	Chryseobacterium			aminopenicillins, AMC, SAM, TIC, TCC, CRO, CTX, CAZ, ATM, ETP, IPM, MEM, aminoglycosides, polymyxins	R	Table 2: Intrinsic resistance in non-fermentative gram-negative bacteria	Expert Rules	3.3	Additional rules from header added in separate rule (genus is one of…)
genus_species	is	Haemophilus influenzae			FUS, streptogramins, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.3	
genus_species	is	Moraxella catarrhalis			TMP, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.3	
genus	is	Neisseria			TMP, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.3	
genus_species	is	Campylobacter fetus			FUS, streptogramins, TMP, NAL, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.3	
fullname	like	^Campylobacter (jejuni|coli)			FUS, streptogramins, TMP, glycopeptides_except_lipo, lipoglycopeptides, lincosamides, oxazolidinones	R	Table 3: Intrinsic resistance in other gram-negative bacteria	Expert Rules	3.3	
gramstain	is	Gram-positive			ATM, TEM, polymyxins, NAL	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Staphylococcus saprophyticus			FUS, CAZ, FOS, NOV	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Staphylococcus cohnii			CAZ, NOV	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Staphylococcus xylosus			CAZ, NOV	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Staphylococcus capitis			CAZ, FOS	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Staphylococcus aureus			CAZ	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Staphylococcus coagulase-negative			CAZ	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus	is	Streptococcus			FUS, CAZ, aminoglycosides	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Enterococcus faecalis			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, SDI, SUD, SDM, SLF, SLF1, SLF2, SZO, SLF3, SLF4, SMX, SLF5, SLF6, SLF7, SLF8, SLF9, SLF10, SLF11, SLF12, SUT, SLF13	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	These last ones are all true sulfonamides
genus_species	is	Enterococcus faecalis	TMP	S	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	S	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecalis	TMP	I	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	I	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecalis	TMP	R	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
fullname	like	^Enterococcus (gallinarum|casseliflavus)			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, CLI, QDA, VAN, SDI, SUD, SDM, SLF, SLF1, SLF2, SZO, SLF3, SLF4, SMX, SLF5, SLF6, SLF7, SLF8, SLF9, SLF10, SLF11, SLF12, SUT, SLF13	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	These last ones are all true sulfonamides
fullname	like	^Enterococcus (gallinarum|casseliflavus)	TMP	S	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	S	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
fullname	like	^Enterococcus (gallinarum|casseliflavus)	TMP	I	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	I	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
fullname	like	^Enterococcus (gallinarum|casseliflavus)	TMP	R	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecium			FUS, CAZ, cephalosporins_except_CAZ, aminoglycosides, macrolides, SDI, SUD, SDM, SLF, SLF1, SLF2, SZO, SLF3, SLF4, SMX, SLF5, SLF6, SLF7, SLF8, SLF9, SLF10, SLF11, SLF12, SUT, SLF13	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	These last ones are all true sulfonamides
genus_species	is	Enterococcus faecium	TMP	S	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	S	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecium	TMP	I	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	I	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
genus_species	is	Enterococcus faecium	TMP	R	SXT, SLT1, SLT2, SLT3, SLT4, SLT5	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	Since R to sulfonamides - TMP result is equal with combinations
genus	is	Corynebacterium			FOS	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	is	Listeria monocytogenes			CAZ, cephalosporins_except_CAZ	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus	one_of	Leuconostoc, Pediococcus			VAN, TEC	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus	is	Lactobacillus			VAN, TEC	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
fullname	like	^Clostridium (ramosum|innocuum)			VAN	R	Table 4: Intrinsic resistance in gram-positive bacteria	Expert Rules	3.3	
genus_species	one_of	Escherichia coli, Proteus mirabilis	AMP	R	PIP	R	Expert Rules on Enterobacterales	Expert Rules	3.3	
genus_species	one_of	Escherichia coli, Proteus mirabilis	AMP	S	PIP	S	Expert Rules on Enterobacterales	Expert Rules	3.3	
fullname	like	^(Klebsiella(?! aerogenes)|Raoultella)			PIP	R	Expert Rules on Enterobacterales	Expert Rules	3.3	
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter freundii|Serratia|Morganella morganii|Hafnia alvei|Providencia)	CXM	S	CXM, cephalosporins_2nd	R	Expert Rules on Enterobacterales	Expert Rules	3.3	
genus	one_of	Arsenophonus, Biostraticola, Brenneria, Buchnera, Budvicia, Buttiauxella, Cedecea, Citrobacter, Cosenzaea, Cronobacter, Dickeya, Edwardsiella, Enterobacillus, Enterobacter, Erwinia, Escherichia, Ewingella, Franconibacter, Gibbsiella, Hafnia, Izhakiella, Klebsiella, Kluyvera, Kosakonia, Leclercia, Lelliottia, Leminorella, Lonsdalea, Mangrovibacter, Mixta, Moellerella, Morganella, Obesumbacterium, Pantoea, Pectobacterium, Phaseolibacter, Photorhabdus, Phytobacter, Plesiomonas, Pluralibacter, Pragia, Proteus, Providencia, Pseudescherichia, Pseudocitrobacter, Rahnella, Raoultella, Rosenbergiella, Rouxiella, Saccharobacter, Samsonia, Serratia, Shigella, Shimwellia, Siccibacter, Sodalis, Tatumella, Thorsellia, Trabulsiella, Wigglesworthia, Xenorhabdus, Yersinia, Yokenella	CIP	R	fluoroquinolones	R	Expert Rules on Enterobacterales	Expert Rules	3.3	This is Enterobacterales except Salmonella spp.
fullname	like	^(Serratia|Providencia|Morganella morganii)			TGC	R	Expert Rules on Enterobacterales	Expert Rules	3.3	
genus	is	Salmonella			cephalosporins_2nd	R	Expert Rules on Salmonella	Expert Rules	3.3	
genus	is	Salmonella			aminoglycosides	R	Expert Rules on Salmonella	Expert Rules	3.3	
genus	is	Salmonella	PEF	R	CIP	R	Expert Rules on Salmonella	Expert Rules	3.3	
genus_species	is	Staphylococcus aureus	FOX	R	betalactams	R	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus_species	is	Staphylococcus aureus	FOX	S	betalactams_with_inhibitor	S	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus_species	one_of	Staphylococcus aureus, Staphylococcus lugdunensis	PEN	R	AMP, AMX, AZL, BAM, CRB, CRN, EPC, HET, MEC, MEZ, MTM, PIP, PME, PVM, SBC, TAL, TEM, TIC	R	Expert Rules on Staphylococcus	Expert Rules	3.3	all penicillins without beta-lactamse inhibitor
genus	is	Staphylococcus	ERY, CLI	S	macrolides, lincosamides	S	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	NOR	S	CIP, LVX, MFX, OFX	S	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	LVX	R	fluoroquinolones	R	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	MFX	R	fluoroquinolones	R	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	TCY	S	DOX, MNO, TGC	S	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	TCY	R	DOX, MNO	R	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	VAN	S	lipoglycopeptides	S	Expert Rules on Staphylococcus	Expert Rules	3.3	
genus	is	Staphylococcus	LNZ	S	TZD	S	Expert Rules on Staphylococcus	Expert Rules	3.3	
fullname	like	^Enterococcus (faecalis|faecium)	AMP	R	ureidopenicillins, IPM	R	Expert Rules on Enterococcus	Expert Rules	3.3	
fullname	like	^Enterococcus (faecalis|faecium)	AMX	R	ureidopenicillins, IPM	R	Expert Rules on Enterococcus	Expert Rules	3.3	
genus	is	Enterococcus	NOR	S	CIP, LVX	S	Expert Rules on Enterococcus	Expert Rules	3.3	
genus	is	Enterococcus	VAN	S	lipoglycopeptides	S	Expert Rules on Enterococcus	Expert Rules	3.3	
genus_species	is	Enterococcus faecium			CLI	R	Expert Rules on Enterococcus	Expert Rules	3.3	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	PEN	S	aminopenicillins, cephalosporins, carbapenems	S	Expert Rules on Streptococcus A, B, C and G	Expert Rules	3.3	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	S	LVX, MFX	S	Expert Rules on Streptococcus A, B, C and G	Expert Rules	3.3	
genus_species	one_of	Streptococcus Group A, Streptococcus Group B, Streptococcus Group C, Streptococcus Group G	NOR	R	LVX, MFX	R	Expert Rules on Streptococcus A, B, C and G	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	OXA	S	PHN, PEN, aminopenicillins, cephalosporins_except_CAZ, carbapenems	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	NOR	S	LVX, MFX	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	NOR	R	LVX, MFX	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	LVX	R	fluoroquinolones	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	MFX	R	fluoroquinolones	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	TCY	S	DOX, MNO	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	TCY	R	DOX, MNO	R	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	is	Streptococcus pneumoniae	VAN	S	lipoglycopeptides	S	Expert Rules on Streptococcus pneumoniae	Expert Rules	3.3	
genus_species	one_of	Viridans Group Streptococcus (VGS)	PEN	S	aminopenicillins, CTX, CRO	S	Expert Rules on Viridans Group Streptococci	Expert Rules	3.3	
genus_species	is	Haemophilus influenzae	PEN	S	betalactams	S	Expert Rules on Haemophilus influenzae	Expert Rules	3.3	
genus_species	is	Haemophilus influenzae	NAL	S	fluoroquinolones	S	Expert Rules on Haemophilus influenzae	Expert Rules	3.3	
genus_species	is	Haemophilus influenzae	NAL	R	CIP, LVX, MFX	R	Expert Rules on Haemophilus influenzae	Expert Rules	3.3	
genus_species	is	Haemophilus influenzae	TCY	S	DOX, MNO	S	Expert Rules on Haemophilus influenzae	Expert Rules	3.3	
genus_species	is	Haemophilus influenzae	TCY	R	DOX, MNO	R	Expert Rules on Haemophilus influenzae	Expert Rules	3.3	
genus_species	is	Moraxella catarrhalis	NAL	S	fluoroquinolones	S	Expert Rules on Moraxella catarrhalis	Expert Rules	3.3	
genus_species	is	Moraxella catarrhalis	NAL	R	fluoroquinolones	R	Expert Rules on Moraxella catarrhalis	Expert Rules	3.3	
genus	is	Campylobacter	ERY	S	CLR, AZM	S	Expert Rules on Campylobacter	Expert Rules	3.3	
genus_species	is	Campylobacter	ERY	R	CLR, AZM	R	Expert Rules on Campylobacter	Expert Rules	3.3	
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CTX	S	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.3	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CRO	S	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.3	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CAZ	S	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.3	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CTX	I	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.3	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CRO	I	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.3	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument
fullname	like	^(Enterobacter|Klebsiella aerogenes|Citrobacter braakii|Citrobacter freundii|Citrobacter gillenii|Citrobacter murliniae|Citrobacter rodenticum|Citrobacter sedlakii|Citrobacter werkmanii|Citrobacter youngae|Hafnia alvei|Serratia|Morganella morganii|Providencia)	CAZ	I	CTX, CRO, CAZ		Expert Rules on Enterobacterales (AmpC de-repressed cephalosporins)	Expert Rules	3.3	This is rule 3 and 4 of EUCAST Expert Rules v3.2 on Enterobacterales, result will be set with the 'ampc_derepressed_cephalosporins' argument