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Data Sets with 566 Antimicrobial Drugs

Source: R/data.R
antibiotics.Rd

Two data sets containing all antibiotics/antimycotics and antivirals. Use as.ab() or one of the ab_* functions to retrieve values from the antibiotics data set. Three identifiers are included in this data set: an antibiotic ID (ab, primarily used in this package) as defined by WHONET/EARS-Net, an ATC code (atc) as defined by the WHO, and a Compound ID (cid) as found in PubChem. Other properties in this data set are derived from one or more of these codes. Note that some drugs have multiple ATC codes.

Usage

antibiotics

antivirals

Format

For the antibiotics data set: a tibble with 464 observations and 14 variables:

  • ab
    Antibiotic ID as used in this package (such as AMC), using the official EARS-Net (European Antimicrobial Resistance Surveillance Network) codes where available

  • cid
    Compound ID as found in PubChem

  • name
    Official name as used by WHONET/EARS-Net or the WHO

  • group
    A short and concise group name, based on WHONET and WHOCC definitions

  • atc
    ATC codes (Anatomical Therapeutic Chemical) as defined by the WHOCC, like J01CR02

  • atc_group1
    Official pharmacological subgroup (3rd level ATC code) as defined by the WHOCC, like "Macrolides, lincosamides and streptogramins"

  • atc_group2
    Official chemical subgroup (4th level ATC code) as defined by the WHOCC, like "Macrolides"

  • abbr
    List of abbreviations as used in many countries, also for antibiotic susceptibility testing (AST)

  • synonyms
    Synonyms (often trade names) of a drug, as found in PubChem based on their compound ID

  • oral_ddd
    Defined Daily Dose (DDD), oral treatment, currently available for 170 drugs

  • oral_units
    Units of oral_ddd

  • iv_ddd
    Defined Daily Dose (DDD), parenteral (intravenous) treatment, currently available for 145 drugs

  • iv_units
    Units of iv_ddd

  • loinc
    All LOINC codes (Logical Observation Identifiers Names and Codes) associated with the name of the antimicrobial agent. Use ab_loinc() to retrieve them quickly, see ab_property().

For the antivirals data set: a tibble with 102 observations and 9 variables:

  • atc
    ATC codes (Anatomical Therapeutic Chemical) as defined by the WHOCC

  • cid
    Compound ID as found in PubChem

  • name
    Official name as used by WHONET/EARS-Net or the WHO

  • atc_group
    Official pharmacological subgroup (3rd level ATC code) as defined by the WHOCC

  • synonyms
    Synonyms (often trade names) of a drug, as found in PubChem based on their compound ID

  • oral_ddd
    Defined Daily Dose (DDD), oral treatment

  • oral_units
    Units of oral_ddd

  • iv_ddd
    Defined Daily Dose (DDD), parenteral treatment

  • iv_units
    Units of iv_ddd

An object of class tbl_df (inherits from tbl, data.frame) with 102 rows and 9 columns.

Source

World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology (WHOCC): https://www.whocc.no/atc_ddd_index/

European Commission Public Health PHARMACEUTICALS - COMMUNITY REGISTER: https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm

Details

Properties that are based on an ATC code are only available when an ATC is available. These properties are: atc_group1, atc_group2, oral_ddd, oral_units, iv_ddd and iv_units.

Synonyms (i.e. trade names) were derived from the Compound ID (cid) and consequently only available where a CID is available.

Direct download

Like all data sets in this package, these data sets are publicly available for download in the following formats: R, MS Excel, Apache Feather, Apache Parquet, SPSS, SAS, and Stata. Please visit our website for the download links. The actual files are of course available on our GitHub repository.

WHOCC


This package contains all ~550 antibiotic, antimycotic and antiviral drugs and their Anatomical Therapeutic Chemical (ATC) codes, ATC groups and Defined Daily Dose (DDD) from the World Health Organization Collaborating Centre for Drug Statistics Methodology (WHOCC, https://www.whocc.no) and the Pharmaceuticals Community Register of the European Commission (https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm).

These have become the gold standard for international drug utilisation monitoring and research.

The WHOCC is located in Oslo at the Norwegian Institute of Public Health and funded by the Norwegian government. The European Commission is the executive of the European Union and promotes its general interest.

NOTE: The WHOCC copyright does not allow use for commercial purposes, unlike any other info from this package. See https://www.whocc.no/copyright_disclaimer/.

See also

microorganisms, intrinsic_resistant

Examples

antibiotics
#> # A tibble: 464 × 14
#>    ab        cid name        group atc   atc_g…¹ atc_g…² abbre…³ synon…⁴ oral_…⁵
#>    <ab>    <dbl> <chr>       <chr> <lis> <chr>   <chr>   <list>  <list>    <dbl>
#>  1 AMA      4649 4-aminosal… Anti… <chr> Drugs … Aminos… <chr>   <chr>     12   
#>  2 FCT      3366 5-fluorocy… Anti… <chr> Antifu… Other … <chr>   <chr>     NA   
#>  3 ACM   6450012 Acetylmide… Macr… <chr> NA      NA      <chr>   <chr>     NA   
#>  4 ASP  49787020 Acetylspir… Macr… <chr> NA      NA      <chr>   <chr>     NA   
#>  5 ALS      8954 Aldesulfon… Othe… <chr> Drugs … Drugs … <chr>   <chr>      0.33
#>  6 AMK     37768 Amikacin    Amin… <chr> Aminog… Other … <chr>   <chr>     NA   
#>  7 AKF        NA Amikacin/f… Amin… <chr> NA      NA      <chr>   <chr>     NA   
#>  8 AMX     33613 Amoxicillin Beta… <chr> Beta-l… Penici… <chr>   <chr>      1.5 
#>  9 AMC  23665637 Amoxicilli… Beta… <chr> Beta-l… Combin… <chr>   <chr>      1.5 
#> 10 AXS    465441 Amoxicilli… Beta… <chr> NA      NA      <chr>   <chr>     NA   
#> # … with 454 more rows, 4 more variables: oral_units <chr>, iv_ddd <dbl>,
#> #   iv_units <chr>, loinc <list>, and abbreviated variable names ¹​atc_group1,
#> #   ²​atc_group2, ³​abbreviations, ⁴​synonyms, ⁵​oral_ddd
antivirals
#> # A tibble: 102 × 9
#>    atc           cid name         atc_g…¹ synon…² oral_…³ oral_…⁴ iv_ddd iv_un…⁵
#>    <chr>       <int> <chr>        <chr>   <list>    <dbl> <chr>    <dbl> <chr>  
#>  1 J05AF06    441300 Abacavir     Nucleo… <chr>     0.6   g           NA NA     
#>  2 J05AB01 135398513 Aciclovir    Nucleo… <chr>     4     g            4 g      
#>  3 J05AF08     60871 Adefovir di… Nucleo… <chr>    10     mg          NA NA     
#>  4 J05AE05     65016 Amprenavir   Protea… <chr>     1.2   g           NA NA     
#>  5 J05AP06  16076883 Asunaprevir  Antivi… <chr>    NA     NA          NA NA     
#>  6 J05AE08    148192 Atazanavir   Protea… <chr>     0.3   g           NA NA     
#>  7 J05AR15  86583336 Atazanavir … Antivi… <chr>    NA     NA          NA NA     
#>  8 J05AR23        NA Atazanavir … Antivi… <chr>     0.3   g           NA NA     
#>  9 J05AP03  10324367 Boceprevir   Antivi… <chr>     2.4   g           NA NA     
#> 10 J05AB15    446727 Brivudine    Nucleo… <chr>     0.125 g           NA NA     
#> # … with 92 more rows, and abbreviated variable names ¹​atc_group, ²​synonyms,
#> #   ³​oral_ddd, ⁴​oral_units, ⁵​iv_units