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These functions can be used for generating random MIC values and disk diffusion diameters, for AMR data analysis practice. By providing a microorganism and antimicrobial drug, the generated results will reflect reality as much as possible.

Usage

random_mic(size = NULL, mo = NULL, ab = NULL, ...)

random_disk(size = NULL, mo = NULL, ab = NULL, ...)

random_sir(size = NULL, prob_SIR = c(0.33, 0.33, 0.33), ...)

Arguments

size

desired size of the returned vector. If used in a data.frame call or dplyr verb, will get the current (group) size if left blank.

mo

any character that can be coerced to a valid microorganism code with as.mo()

ab

any character that can be coerced to a valid antimicrobial drug code with as.ab()

...

ignored, only in place to allow future extensions

prob_SIR

a vector of length 3: the probabilities for "S" (1st value), "I" (2nd value) and "R" (3rd value)

Value

class mic for random_mic() (see as.mic()) and class disk for random_disk() (see as.disk())

Details

The base R function sample() is used for generating values.

Generated values are based on the EUCAST 2022 guideline as implemented in the clinical_breakpoints data set. To create specific generated values per bug or drug, set the mo and/or ab argument.

Examples

random_mic(25)
#> Class 'mic'
#>  [1] 32    2     1     2     32    0.005 8     64    128   128   256   16   
#> [13] 0.005 0.01  16    0.5   4     0.001 2     64    0.001 0.002 16    0.01 
#> [25] 128  
random_disk(25)
#> Class 'disk'
#>  [1] 48 19 44 26 24 40 49  9 50 47 12 47 34 17 37 13 47 21 36 20 29  6 30 49 43
random_sir(25)
#> Class 'sir'
#>  [1] S I S S S I I S S R I I R R S I I S I S S R I R I

# \donttest{
# make the random generation more realistic by setting a bug and/or drug:
random_mic(25, "Klebsiella pneumoniae") # range 0.0625-64
#> Class 'mic'
#>  [1] 32      64      8       0.5     0.25    8       0.0625  32      16     
#> [10] 0.0625  <=0.001 0.25    2       0.005   0.125   0.01    0.025   0.025  
#> [19] 0.5     32      0.025   16      32      >=128   2      
random_mic(25, "Klebsiella pneumoniae", "meropenem") # range 0.0625-16
#> Class 'mic'
#>  [1] 8    0.5  2    16   1    8    1    0.25 0.5  2    8    8    1    4    8   
#> [16] 1    2    16   16   2    16   2    0.5  4    8   
random_mic(25, "Streptococcus pneumoniae", "meropenem") # range 0.0625-4
#> Class 'mic'
#>  [1] 0.5   >=8   1     0.25  1     2     >=8   0.125 0.25  0.125 0.25  1    
#> [13] 0.125 0.25  0.25  0.25  >=8   0.125 0.5   0.25  0.125 0.25  1     0.5  
#> [25] 0.125

random_disk(25, "Klebsiella pneumoniae") # range 8-50
#> Class 'disk'
#>  [1] 41 35 31 49 20 49 19 45 43 17 45 47 40 28 19 48 11 40 13 28 48 39 20 17 23
random_disk(25, "Klebsiella pneumoniae", "ampicillin") # range 11-17
#> Class 'disk'
#>  [1] 11 11 15 15 14 17 12 16 17 14 12 11 11 16 13 14 14 12 17 14 14 11 12 14 13
random_disk(25, "Streptococcus pneumoniae", "ampicillin") # range 12-27
#> Class 'disk'
#>  [1] 21 23 27 25 16 16 20 20 23 23 18 19 15 23 15 24 22 25 21 17 25 15 16 18 22
# }