# ==================================================================== # # TITLE # # Antimicrobial Resistance (AMR) Analysis for R # # # # SOURCE # # https://github.com/msberends/AMR # # # # LICENCE # # (c) 2018-2020 Berends MS, Luz CF et al. # # Developed at the University of Groningen, the Netherlands, in # # collaboration with non-profit organisations Certe Medical # # Diagnostics & Advice, and University Medical Center Groningen. # # # # This R package is free software; you can freely use and distribute # # it for both personal and commercial purposes under the terms of the # # GNU General Public License version 2.0 (GNU GPL-2), as published by # # the Free Software Foundation. # # We created this package for both routine data analysis and academic # # research and it was publicly released in the hope that it will be # # useful, but it comes WITHOUT ANY WARRANTY OR LIABILITY. # # # # Visit our website for the full manual and a complete tutorial about # # how to conduct AMR analysis: https://msberends.github.io/AMR/ # # ==================================================================== # #' User-defined reference data set for microorganisms #' #' @description These functions can be used to predefine your own reference to be used in [as.mo()] and consequently all `mo_*` functions like [mo_genus()] and [mo_gramstain()]. #' #' This is **the fastest way** to have your organisation (or analysis) specific codes picked up and translated by this package. #' @inheritSection lifecycle Stable lifecycle #' @param path location of your reference file, see Details. Can be `""`, `NULL` or `FALSE` to delete the reference file. #' @param destination destination of the compressed data file, default to the user's home directory. #' @rdname mo_source #' @name mo_source #' @aliases set_mo_source get_mo_source #' @details The reference file can be a text file separated with commas (CSV) or tabs or pipes, an Excel file (either 'xls' or 'xlsx' format) or an R object file (extension '.rds'). To use an Excel file, you will need to have the `readxl` package installed. #' #' [set_mo_source()] will check the file for validity: it must be a [data.frame], must have a column named `"mo"` which contains values from [`microorganisms$mo`][microorganisms] and must have a reference column with your own defined values. If all tests pass, [set_mo_source()] will read the file into R and will ask to export it to `"~/mo_source.rds"`. The CRAN policy disallows packages to write to the file system, although '*exceptions may be allowed in interactive sessions if the package obtains confirmation from the user*'. For this reason, this function only works in interactive sessions so that the user can **specifically confirm and allow** that this file will be created. The destination of this file can be set with the `destination` parameter and defaults to the user's home directory. It can also be set as an \R option, using `options(AMR_mo_source = "my/location/file.rds)`. #' #' The created compressed data file `"mo_source.rds"` will be used at default for MO determination (function [as.mo()] and consequently all `mo_*` functions like [mo_genus()] and [mo_gramstain()]). The location and timestamp of the original file will be saved as an attribute to the compressed data file. #' #' The function [get_mo_source()] will return the data set by reading `"mo_source.rds"` with [readRDS()]. If the original file has changed (by checking the location and timestamp of the original file), it will call [set_mo_source()] to update the data file automatically if used in an interactive session. #' #' Reading an Excel file (`.xlsx`) with only one row has a size of 8-9 kB. The compressed file created with [set_mo_source()] will then have a size of 0.1 kB and can be read by [get_mo_source()] in only a couple of microseconds (millionths of a second). #' #' @section How to setup: #' #' Imagine this data on a sheet of an Excel file (mo codes were looked up in the [microorganisms] data set). The first column contains the organisation specific codes, the second column contains an MO code from this package: #' #' ``` #' | A | B | #' --|--------------------|--------------| #' 1 | Organisation XYZ | mo | #' 2 | lab_mo_ecoli | B_ESCHR_COLI | #' 3 | lab_mo_kpneumoniae | B_KLBSL_PNMN | #' 4 | | | #' ``` #' #' We save it as `"home/me/ourcodes.xlsx"`. Now we have to set it as a source: #' #' ``` #' set_mo_source("home/me/ourcodes.xlsx") #' #> NOTE: Created mo_source file '/Users/me/mo_source.rds' (0.3 kB) from #' #> '/Users/me/Documents/ourcodes.xlsx' (9 kB), columns #' #> "Organisation XYZ" and "mo" #' ``` #' #' It has now created a file `"~/mo_source.rds"` with the contents of our Excel file. Only the first column with foreign values and the 'mo' column will be kept when creating the RDS file. #' #' And now we can use it in our functions: #' #' ``` #' as.mo("lab_mo_ecoli") #' #> Class #' #> [1] B_ESCHR_COLI #' #' mo_genus("lab_mo_kpneumoniae") #' #> [1] "Klebsiella" #' #' # other input values still work too #' as.mo(c("Escherichia coli", "E. coli", "lab_mo_ecoli")) #' #> NOTE: Translation to one microorganism was guessed with uncertainty. #' #> Use mo_uncertainties() to review it. #' #> Class #' #> [1] B_ESCHR_COLI B_ESCHR_COLI B_ESCHR_COLI #' ``` #' #' If we edit the Excel file by, let's say, adding row 4 like this: #' #' ``` #' | A | B | #' --|--------------------|--------------| #' 1 | Organisation XYZ | mo | #' 2 | lab_mo_ecoli | B_ESCHR_COLI | #' 3 | lab_mo_kpneumoniae | B_KLBSL_PNMN | #' 4 | lab_Staph_aureus | B_STPHY_AURS | #' 5 | | | #' ``` #' #' ...any new usage of an MO function in this package will update your data file: #' #' ``` #' as.mo("lab_mo_ecoli") #' #> NOTE: Updated mo_source file '/Users/me/mo_source.rds' (0.3 kB) from #' #> '/Users/me/Documents/ourcodes.xlsx' (9 kB), columns #' #> "Organisation XYZ" and "mo" #' #> Class #' #> [1] B_ESCHR_COLI #' #' mo_genus("lab_Staph_aureus") #' #> [1] "Staphylococcus" #' ``` #' #' To delete the reference data file, just use `""`, `NULL` or `FALSE` as input for [set_mo_source()]: #' #' ``` #' set_mo_source(NULL) #' #> Removed mo_source file '/Users/me/mo_source.rds' #' ``` #' #' If the original Excel file is moved or deleted, the mo_source file will be removed upon the next use of [as.mo()]. #' @export #' @inheritSection AMR Read more on our website! set_mo_source <- function(path, destination = getOption("AMR_mo_source", "~/mo_source.rds")) { meet_criteria(path, allow_class = "character", has_length = 1, allow_NULL = TRUE) meet_criteria(destination, allow_class = "character", has_length = 1) stop_ifnot(destination %like% "[.]rds$", "the `destination` must be a file location with file extension .rds") mo_source_destination <- path.expand(destination) stop_ifnot(interactive(), "This function can only be used in interactive mode, since it must ask for the user's permission to write a file to their home folder.") if (is.null(path) || path %in% c(FALSE, "")) { mo_env$mo_source <- NULL if (file.exists(mo_source_destination)) { unlink(mo_source_destination) message_("Removed mo_source file '", font_bold(mo_source_destination), "'", add_fn = font_red, as_note = FALSE) } return(invisible()) } stop_ifnot(file.exists(path), "file not found: ", path) if (path %like% "[.]rds$") { df <- readRDS(path) } else if (path %like% "[.]xlsx?$") { # is Excel file (old or new) read_excel <- import_fn("read_excel", "readxl") df <- read_excel(path) } else if (path %like% "[.]tsv$") { df <- utils::read.table(header = TRUE, sep = "\t", stringsAsFactors = FALSE) } else { # try comma first try( df <- utils::read.table(header = TRUE, sep = ",", stringsAsFactors = FALSE), silent = TRUE) if (!mo_source_isvalid(df, stop_on_error = FALSE)) { # try tab try( df <- utils::read.table(header = TRUE, sep = "\t", stringsAsFactors = FALSE), silent = TRUE) } if (!mo_source_isvalid(df, stop_on_error = FALSE)) { # try pipe try( df <- utils::read.table(header = TRUE, sep = "|", stringsAsFactors = FALSE), silent = TRUE) } } # check integrity mo_source_isvalid(df) df <- subset(df, !is.na(mo)) # keep only first two columns, second must be mo if (colnames(df)[1] == "mo") { df <- df[, c(colnames(df)[2], "mo")] } else { df <- df[, c(colnames(df)[1], "mo")] } df <- as.data.frame(df, stringAsFactors = FALSE) df[, "mo"] <- set_clean_class(df[, "mo", drop = TRUE], c("mo", "character")) # success if (file.exists(mo_source_destination)) { action <- "Updated" } else { action <- "Created" # only ask when file is created, not when it is updated txt <- paste0(word_wrap(paste0("This will write create the new file '", mo_source_destination, "', for which your permission is needed.")), "\n\n", word_wrap("Do you agree that this file will be created?")) if ("rsasdtudioapi" %in% rownames(utils::installed.packages())) { showQuestion <- import_fn("showQuestion", "rstudioapi") q_continue <- showQuestion("Create new file in home directory", txt) } else { q_continue <- utils::menu(choices = c("OK", "Cancel"), graphics = FALSE, title = txt) } if (q_continue %in% c(FALSE, 2)) { return(invisible()) } } attr(df, "mo_source_location") <- path attr(df, "mo_source_timestamp") <- file.mtime(path) saveRDS(df, mo_source_destination) mo_env$mo_source <- df message_(action, " mo_source file '", font_bold(mo_source_destination), "' (", formatted_filesize(mo_source_destination), ") from '", font_bold(path), "' (", formatted_filesize(path), '), columns "', colnames(df)[1], '" and "', colnames(df)[2], '"') } #' @rdname mo_source #' @export get_mo_source <- function(destination = getOption("AMR_mo_source", "~/mo_source.rds")) { if (!file.exists(path.expand(destination))) { if (interactive()) { # source file might have been deleted, update reference set_mo_source("") } return(NULL) } if (is.null(mo_env$mo_source)) { mo_env$mo_source <- readRDS(path.expand(destination)) } old_time <- attributes(mo_env$mo_source)$mo_source_timestamp new_time <- file.mtime(attributes(mo_env$mo_source)$mo_source_location) if (interactive() && !identical(old_time, new_time)) { # source file was updated, also update reference set_mo_source(attributes(mo_env$mo_source)$mo_source_location) } mo_env$mo_source } mo_source_isvalid <- function(x, refer_to_name = "`reference_df`", stop_on_error = TRUE) { check_dataset_integrity() if (paste(deparse(substitute(x)), collapse = "") == "get_mo_source()") { return(TRUE) } if (is.null(mo_env$mo_source) && (identical(x, get_mo_source()))) { return(TRUE) } if (is.null(x)) { if (stop_on_error == TRUE) { stop_(refer_to_name, " cannot be NULL", call = FALSE) } else { return(FALSE) } } if (!is.data.frame(x)) { if (stop_on_error == TRUE) { stop_(refer_to_name, " must be a data.frame", call = FALSE) } else { return(FALSE) } } if (!"mo" %in% colnames(x)) { if (stop_on_error == TRUE) { stop_(refer_to_name, " must contain a column 'mo'", call = FALSE) } else { return(FALSE) } } if (!all(x$mo %in% c("", microorganisms$mo, microorganisms.translation$mo_old), na.rm = TRUE)) { if (stop_on_error == TRUE) { invalid <- x[which(!x$mo %in% c("", microorganisms$mo, microorganisms.translation$mo_old)), , drop = FALSE] if (nrow(invalid) > 1) { plural <- "s" } else { plural <- "" } stop_("Value", plural, " ", paste0("'", invalid[, 1, drop = TRUE], "'", collapse = ", "), " found in ", tolower(refer_to_name), ", but with invalid microorganism code", plural, " ", paste0("'", invalid$mo, "'", collapse = ", "), call = FALSE) } else { return(FALSE) } } if (colnames(x)[1] != "mo" & nrow(x) > length(unique(x[, 1, drop = TRUE]))) { if (stop_on_error == TRUE) { stop_(refer_to_name, " contains duplicate values in column '", colnames(x)[1], "'", call = FALSE) } else { return(FALSE) } } if (colnames(x)[2] != "mo" & nrow(x) > length(unique(x[, 2, drop = TRUE]))) { if (stop_on_error == TRUE) { stop_(refer_to_name, " contains duplicate values in column '", colnames(x)[2], "'", call = FALSE) } else { return(FALSE) } } return(TRUE) }