This function determines which items in a vector can be considered (the start of) a new episode, based on the argument episode_days. This can be used to determine clinical episodes for any epidemiological analysis.

is_new_episode(x, episode_days = 365, ...)

Arguments

x

vector of dates (class Date or POSIXt)

episode_days

length of the required episode in days, defaults to 365. Every element in the input will return TRUE after this number of days has passed since the last included date, independent of calendar years. Please see Details.

...

arguments passed on to as.Date()

Value

a logical vector

Details

Dates are first sorted from old to new. The oldest date will mark the start of the first episode. After this date, the next date will be marked that is at least episode_days days later than the start of the first episode. From that second marked date on, the next date will be marked that is at least episode_days days later than the start of the second episode which will be the start of the third episode, and so on. Before the vector is being returned, the original order will be restored.

The first_isolate() function is a wrapper around the is_new_episode() function, but more efficient for data sets containing microorganism codes or names.

The dplyr package is not required for this function to work, but this function works conveniently inside dplyr verbs such as filter(), mutate() and summarise().

Stable lifecycle


The lifecycle of this function is stable. In a stable function, major changes are unlikely. This means that the unlying code will generally evolve by adding new arguments; removing arguments or changing the meaning of existing arguments will be avoided.

If the unlying code needs breaking changes, they will occur gradually. For example, a argument will be deprecated and first continue to work, but will emit an message informing you of the change. Next, typically after at least one newly released version on CRAN, the message will be transformed to an error.

Read more on our website!

On our website https://msberends.github.io/AMR/ you can find a comprehensive tutorial about how to conduct AMR analysis, the complete documentation of all functions and an example analysis using WHONET data. As we would like to better understand the backgrounds and needs of our users, please participate in our survey!

Examples

# `example_isolates` is a dataset available in the AMR package.
# See ?example_isolates.

is_new_episode(example_isolates$date)
is_new_episode(example_isolates$date, episode_days = 60)
# \donttest{
if (require("dplyr")) {
  # is_new_episode() can also be used in dplyr verbs to determine patient
  # episodes based on any (combination of) grouping variables:
  example_isolates %>%
    mutate(condition = sample(x = c("A", "B", "C"), 
                              size = 2000,
                              replace = TRUE)) %>% 
    group_by(condition) %>%
    mutate(new_episode = is_new_episode(date))
  
  example_isolates %>%
    group_by(hospital_id) %>% 
    summarise(patients = n_distinct(patient_id),
              n_episodes_365 = sum(is_new_episode(date, episode_days = 365)),
              n_episodes_60  = sum(is_new_episode(date, episode_days = 60)),
              n_episodes_30  = sum(is_new_episode(date, episode_days = 30)))
    
    
  # grouping on patients and microorganisms leads to the same results
  # as first_isolate():
  x <- example_isolates %>%
    filter(first_isolate(., include_unknown = TRUE))
    
  y <- example_isolates %>%
    group_by(patient_id, mo) %>%
    filter(is_new_episode(date))

  identical(x$patient_id, y$patient_id)
  
  # but is_new_episode() has a lot more flexibility than first_isolate(),
  # since you can now group on anything that seems relevant:
  example_isolates %>%
    group_by(patient_id, mo, hospital_id, ward_icu) %>%
    mutate(flag_episode = is_new_episode(date))
}
# }