Gram-positive anaerobes
except Clostridioides difficile
The Mycobacterium tuberculosis complex includes different species and variants such as M. tuberculosis var. canetti, M. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.
The Mycobacterium tuberculosis complex includes different species and variants such as M. tuberculosis var. canetti,M. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.
The Mycobacterium tuberculosis complex includes different species and variants such asM. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.
Corynebacterium spp.other than C. diphtheriae and C. ulcerans
Corynebacterium diphtheriae and C. ulcerans
Fusobacterium necrophorum and Fusobacterium nucleatum

Amoxicillin-clavulanic acid (uncomplicated UTI only)
Mecillinam (uncomplicated UTI only)
E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and 
P. mirabilis
Cefuroxime iv, E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilis
Cefuroxime oral (uncomplicated UTI only), E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and 
P. mirabilis
Imipenem, Morganella morganii,Proteus spp. and Providencia spp.
Fosfomycin oral 
(uncomplicated UTI only)
Nitrofurantoin (uncomplicated UTI only), E. coli
Nitroxoline (uncomplicated UTI only), 
E. coli
Cefoxitin (screen), S. aureus and coagulase-negative staphylococci other than S. epidermidis
Ceftaroline, S. aureus (indications other than pneumonia)
Nitrofurantoin (uncomplicated UTI only), S. saprophyticus
Nitroxoline (uncomplicated UTI only), S. saprophyticus
Gentamicin (test for high-level aminoglycoside resistance)
Streptomycin (test for high-level streptomycin resistance)
Nitrofurantoin (uncomplicated UTI only), E. faecalis
Phenoxymethylpenicillin
Streptococcus groups A, C and G
Cloxacillin
Streptococcus groups A, C and G
Dicloxacillin
Streptococcus groups A, C and G
Flucloxacillin 
Streptococcus groups A, C and G
Nitrofurantoin (uncomplicated UTI only), 
S. agalactiae (group B streptococci)
Trimethoprim (uncomplicated UTI only), S. agalactiae (group B streptococci)
Benzylpenicillin (indications other than meningitis)
Meropenem (indications other than meningitis)
Mecillinam oral (uncomplicated UTI only), E. coli, Citrobacter spp., Klebsiella spp., Raoultella spp., Enterobacter spp. and P. mirabilis
Cefazolin (infections originating from the urinary tract), E. coli, and Klebsiella spp. (except K. aerogenes)
Ceftibuten (infections originating from the urinary tract)
Imipenem-relebactam, Enterobacterales except Morganella spp.
Amikacin (infections originating from the urinary tract)
Gentamicin (infections originating from the urinary tract)
Tobramycin (infections originating from the urinary tract)
Cefoxitin (screen only), S. aureus and coagulase-negative staphylococci other than S. epidermidis
Cefoxitin (screen only), S. pseudintermedius and S. schleiferi
Oxacillin 
Streptococcus groups A, C and G
Temocillin (infections originating from the urinary tract), E. coli, Klebsiella spp. (except K. aerogenes) and P. mirabilis
Mecillinam oral (pivmecillinam) (uncomplicated UTI only), E. coli, Citrobacter spp., Klebsiella spp., Raoultella spp., Enterobacter spp. and P. mirabilis
Cefotaxime (indications other than meningitis)
Ceftriaxone (indications other than meningitis)
Fosfomycin oral 
(uncomplicated UTI only), E. coli
Oxacillin (screen only), 
S. pseudintermedius and S. schleiferi
Cefoxitin (screen only), 
S. pseudintermedius and S. schleiferi
Ceftaroline(indications other than pneumonia), S. aureus
Benzylpenicillin (meningitis),  S. agalactiae (group B streptococci)
Ampicillin (indications other than meningitis)
Amoxicillin iv (indications other than meningitis)
Amoxicillin (indications other than meningitis)
Mecillinam oral (pivmecillinam) (uncomplicated UTI only),E. coli, Citrobacter spp. Klebsiella spp., 
Raoultella spp., Enterobacter spp. and P. mirabilis
Meropenem (indications other than meningitis), P. aeruginosa
Meropenem(indications other than meningitis),Pseudomonas other than P. aeruginosa
Oxacillin (screen only), S. pseudinter-medius, S. schleiferi and S. coagulans
Cefoxitin (screen only), S. aureus and coagulase-negative staphylococci except S. epidermidis and S. lugdunensis
Cefoxitin (screen only), S. epidermidis and S.lugdunensis
Cefoxitin (screen only), 
S. pseudintermedius, S. schleiferi and
S. coagulans
Ceftaroline (indications other than pneumonia), S. aureus
Delafloxacin (community-acquired pneumonia), S. aureus
Delafloxacin (skin and skin structure infections), S. aureus
Nitrofurantoin (uncomplicated UTI only),S. saprophyticus
Nitroxoline (uncomplicated UTI only), 
S. saprophyticus
Ceftriaxone (all indications including prophylaxis)
Erythromycin (indications other than meningitis)
Ampicillin oral (uncomplicated UTI only)
Ampicillin-sulbactam oral (uncomplicated UTI only)
Amoxicillin oral (infections originating from the urinary tract)
Amoxicillin oral (uncomplicated UTI only)
Amoxicillin-clavulanic acid oral (infections originating from the urinary tract)
Amoxicillin-clavulanic acid oral (uncomplicated UTI only)
Amoxicillin-clavulanic acid oral (other indications)
Mecillinam oral (pivmecillinam) (uncomplicated UTI only),E. coli, Citrobacter spp., Klebsiella spp., Raoultella spp., Enterobacter spp. and P. mirabilis
Cefazolin (infections originating from the urinary tract), E. coli and Klebsiella spp. (except K. aerogenes)
Ciprofloxacin (indications other than meningitis)
Oxacillin (screen only), S. pseudintermedius, S. schleiferi and S. coagulans
Cefoxitin (screen only), S. epidermidis and S. lugdunensis
Ciprofloxacin (all indications, including meningitis and prophylaxis)
Cefuroxime oral (uncomplicated UTI only), E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilis
Cefazolin (infections originating from the urinary tract), E. coli and Klebsiella spp.(except K. aerogenes)
Moxifloxacin, Enterobacterales except Morganella morganii, Proteus spp. and Serratia spp.
Fosfomycin iv (infections originating from the urinary tract), E. coli
Fosfomycin iv (other indications), E. coli
Oxacillin (screen only), S. pseudintermedius, S. intermedius, S. schleiferi and S. coagulans
Cefoxitin (screen only), S. pseudintermedius, S. intermedius, S. schleiferi and S. coagulans
Gentamicin (test for acquired aminoglycoside-modifying enzyme)
Streptomycin (test for acquired aminoglycoside-modifying enzyme)
Vancomycin, enterococci other than E. casseliflavus and E. gallinarum
Fosfomycin iv (other indications), 
E. coli
Amoxicillin oral (other indications),E. faecalis
Amoxicillin-clavulanic acid oral (other indications),E. faecalis
Benzylpenicillin, Streptococcus groups A, C and G
Benzylpenicillin,  S. agalactiae (group B streptococci)
Benzylpenicillin (indications other than endocarditis and meningitis)
Ampicillin (indications other than endocarditis and meningitis)
Ampicillin iv (endocarditis and meningitis)
Amoxicillin iv (indications other than endocarditis and meningitis)
Amoxicillin iv (endocarditis and meningitis)
Cefotaxime (indications other than endocarditis and meningitis)
Ceftriaxone (indications other than endocarditis and meningitis)
Benzylpenicillin (indications other than endocarditis)
Benzylpenicillin (endocarditis, in combination with other antimicrobial treatment)
Ampicillin (indications other than endocarditis)
Amoxicillin (indications other than endocarditis)
Gepotidacin (uncomplicated UTI only),E. coli
Trimethoprim (uncomplicated UTI only), E. coli and Klebsiella spp. (except K. aerogenes)
Trimethoprim (uncomplicated UTI only), Proteus spp.
Trimethoprim-sulfamethoxazole, 
Enterobacterales except Serratia spp.
Meropenem(indications other than meningitis),Pseudomonas other than 
P. aeruginosa
Cefoxitin (screen only), S. aureus and coagulase-negative staphylococci except 
S. epidermidis and S. lugdunensis
Gepotidacin (uncomplicated UTI only),S. saprophyticus
Gepotidacin (uncomplicated UTI only),E. faecalis
Nitrofurantoin (uncomplicated UTI only), 
E. faecalis
Ampicillin iv (indications other than endocarditis and meningitis)