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These functions can be used for generating random MIC values and disk diffusion diameters, for AMR data analysis practice. By providing a microorganism and antimicrobial drug, the generated results will reflect reality as much as possible.

Usage

random_mic(size = NULL, mo = NULL, ab = NULL, ...)

random_disk(size = NULL, mo = NULL, ab = NULL, ...)

random_sir(size = NULL, prob_SIR = c(0.33, 0.33, 0.33), ...)

Arguments

size

desired size of the returned vector. If used in a data.frame call or dplyr verb, will get the current (group) size if left blank.

mo

any character that can be coerced to a valid microorganism code with as.mo()

ab

any character that can be coerced to a valid antimicrobial drug code with as.ab()

...

ignored, only in place to allow future extensions

prob_SIR

a vector of length 3: the probabilities for "S" (1st value), "I" (2nd value) and "R" (3rd value)

Value

class mic for random_mic() (see as.mic()) and class disk for random_disk() (see as.disk())

Details

The base R function sample() is used for generating values.

Generated values are based on the EUCAST 2022 guideline as implemented in the clinical_breakpoints data set. To create specific generated values per bug or drug, set the mo and/or ab argument.

Examples

random_mic(25)
#> Class 'mic'
#>  [1] 8      64     8      64     128    4      0.25   8      0.002  4     
#> [11] 0.01   128    0.0625 32     128    0.025  0.025  0.005  0.025  128   
#> [21] 32     1      64     64     16    
random_disk(25)
#> Class 'disk'
#>  [1] 41 29 23  6 49 23 25 45 18 36 10 40 40 26  9 23 48 39 36 27 12 48 30 29 12
random_sir(25)
#> Class 'sir'
#>  [1] I I I R I R R R I R S I R R I S I I I S R S I I I

# \donttest{
# make the random generation more realistic by setting a bug and/or drug:
random_mic(25, "Klebsiella pneumoniae") # range 0.0625-64
#> Class 'mic'
#>  [1] 16    32    0.125 1     >=64  2     0.001 0.002 >=64  0.5   0.005 0.5  
#> [13] 0.125 4     4     4     16    32    16    0.5   0.001 0.002 8     0.002
#> [25] 1    
random_mic(25, "Klebsiella pneumoniae", "meropenem") # range 0.0625-16
#> Class 'mic'
#>  [1] 0.25 32   1    32   2    2    4    0.5  4    4    0.25 32   0.5  0.5  8   
#> [16] 32   0.5  1    32   1    8    8    16   0.25 0.25
random_mic(25, "Streptococcus pneumoniae", "meropenem") # range 0.0625-4
#> Class 'mic'
#>  [1] 0.125   <=0.025 2       0.25    8       8       >=16    2       0.125  
#> [10] 1       0.125   2       0.5     8       0.5     <=0.025 0.125   >=16   
#> [19] 0.125   2       8       1       8       0.0625  0.125  

random_disk(25, "Klebsiella pneumoniae") # range 8-50
#> Class 'disk'
#>  [1] 35 44 14 44 42 36 19 46 26 44 40 40 18 12 22 48 20  8 25 42 37 21 21 50 50
random_disk(25, "Klebsiella pneumoniae", "ampicillin") # range 11-17
#> Class 'disk'
#>  [1] 14 11 12 12 11 14 12 17 17 11 16 13 12 11 11 16 16 11 11 16 16 15 17 12 16
random_disk(25, "Streptococcus pneumoniae", "ampicillin") # range 12-27
#> Class 'disk'
#>  [1] 21 24 16 21 17 15 20 23 15 20 24 16 21 21 18 19 26 17 22 22 19 17 24 18 17
# }