mirror of
https://github.com/msberends/AMR.git
synced 2024-12-26 18:46:13 +01:00
315 lines
12 KiB
R
Executable File
315 lines
12 KiB
R
Executable File
# ==================================================================== #
|
|
# TITLE #
|
|
# Antimicrobial Resistance (AMR) Analysis #
|
|
# #
|
|
# SOURCE #
|
|
# https://gitlab.com/msberends/AMR #
|
|
# #
|
|
# LICENCE #
|
|
# (c) 2019 Berends MS (m.s.berends@umcg.nl), Luz CF (c.f.luz@umcg.nl) #
|
|
# #
|
|
# This R package is free software; you can freely use and distribute #
|
|
# it for both personal and commercial purposes under the terms of the #
|
|
# GNU General Public License version 2.0 (GNU GPL-2), as published by #
|
|
# the Free Software Foundation. #
|
|
# #
|
|
# This R package was created for academic research and was publicly #
|
|
# released in the hope that it will be useful, but it comes WITHOUT #
|
|
# ANY WARRANTY OR LIABILITY. #
|
|
# Visit our website for more info: https://msberends.gitlab.io/AMR. #
|
|
# ==================================================================== #
|
|
|
|
# No export, no Rd
|
|
addin_insert_in <- function() {
|
|
rstudioapi::insertText(" %in% ")
|
|
}
|
|
|
|
# No export, no Rd
|
|
addin_insert_like <- function() {
|
|
rstudioapi::insertText(" %like% ")
|
|
}
|
|
|
|
# No export, no Rd
|
|
# works exactly like round(), but rounds `round(44.55, 1)` as 44.6 instead of 44.5
|
|
# and adds decimal zeroes until `digits` is reached when force_zero = TRUE
|
|
round2 <- function(x, digits = 0, force_zero = TRUE) {
|
|
# https://stackoverflow.com/a/12688836/4575331
|
|
val <- (trunc((abs(x) * 10 ^ digits) + 0.5) / 10 ^ digits) * sign(x)
|
|
if (digits > 0 & force_zero == TRUE) {
|
|
val[val != as.integer(val)] <- paste0(val[val != as.integer(val)],
|
|
strrep("0", max(0, digits - nchar(gsub(".*[.](.*)$", "\\1", val[val != as.integer(val)])))))
|
|
}
|
|
val
|
|
}
|
|
|
|
# Coefficient of variation (CV)
|
|
cv <- function(x, na.rm = TRUE) {
|
|
stats::sd(x, na.rm = na.rm) / base::abs(base::mean(x, na.rm = na.rm))
|
|
}
|
|
|
|
# Coefficient of dispersion, or coefficient of quartile variation (CQV).
|
|
# (Bonett et al., 2006: Confidence interval for a coefficient of quartile variation).
|
|
cqv <- function(x, na.rm = TRUE) {
|
|
fives <- stats::fivenum(x, na.rm = na.rm)
|
|
(fives[4] - fives[2]) / (fives[4] + fives[2])
|
|
}
|
|
|
|
# show bytes as kB/MB/GB
|
|
# size_humanreadable(123456) # 121 kB
|
|
# size_humanreadable(12345678) # 11.8 MB
|
|
size_humanreadable <- function(bytes, decimals = 1) {
|
|
bytes <- bytes %>% as.double()
|
|
# Adapted from:
|
|
# http://jeffreysambells.com/2012/10/25/human-readable-filesize-php
|
|
size <- c('B','kB','MB','GB','TB','PB','EB','ZB','YB')
|
|
factor <- floor((nchar(bytes) - 1) / 3)
|
|
# added slight improvement; no decimals for B and kB:
|
|
decimals <- rep(decimals, length(bytes))
|
|
decimals[size[factor + 1] %in% c('B', 'kB')] <- 0
|
|
|
|
out <- paste(sprintf(paste0("%.", decimals, "f"), bytes / (1024 ^ factor)), size[factor + 1])
|
|
out
|
|
}
|
|
|
|
percent_scales <- scales::percent
|
|
# No export, no Rd
|
|
# based on scales::percent
|
|
percent <- function(x, round = 1, force_zero = FALSE, decimal.mark = getOption("OutDec"), ...) {
|
|
x <- percent_scales(x = as.double(x),
|
|
accuracy = 1 / 10 ^ round,
|
|
decimal.mark = decimal.mark,
|
|
...)
|
|
if (force_zero == FALSE) {
|
|
x <- gsub("([.]%|%%)", "%", paste0(gsub("0+%$", "", x), "%"))
|
|
}
|
|
x
|
|
}
|
|
|
|
#' @importFrom crayon blue bold red
|
|
#' @importFrom dplyr %>% pull
|
|
search_type_in_df <- function(tbl, type) {
|
|
# try to find columns based on type
|
|
found <- NULL
|
|
|
|
colnames(tbl) <- trimws(colnames(tbl))
|
|
|
|
# -- mo
|
|
if (type == "mo") {
|
|
if ("mo" %in% lapply(tbl, class)) {
|
|
found <- colnames(tbl)[lapply(tbl, class) == "mo"][1]
|
|
} else if (any(colnames(tbl) %like% "^(mo|microorganism|organism|bacteria)")) {
|
|
found <- colnames(tbl)[colnames(tbl) %like% "^(mo|microorganism|organism|bacteria)"][1]
|
|
} else if (any(colnames(tbl) %like% "species")) {
|
|
found <- colnames(tbl)[colnames(tbl) %like% "species"][1]
|
|
}
|
|
|
|
}
|
|
# -- key antibiotics
|
|
if (type == "keyantibiotics") {
|
|
if (any(colnames(tbl) %like% "^key.*(ab|antibiotics)")) {
|
|
found <- colnames(tbl)[colnames(tbl) %like% "^key.*(ab|antibiotics)"][1]
|
|
}
|
|
}
|
|
# -- date
|
|
if (type == "date") {
|
|
if (any(colnames(tbl) %like% "^(specimen date|specimen_date|spec_date)")) {
|
|
# WHONET support
|
|
found <- colnames(tbl)[colnames(tbl) %like% "^(specimen date|specimen_date|spec_date)"][1]
|
|
if (!any(class(tbl %>% pull(found)) %in% c("Date", "POSIXct"))) {
|
|
stop(red(paste0("ERROR: Found column `", bold(found), "` to be used as input for `col_", type,
|
|
"`, but this column contains no valid dates. Transform its values to valid dates first.")),
|
|
call. = FALSE)
|
|
}
|
|
} else {
|
|
for (i in 1:ncol(tbl)) {
|
|
if (any(class(tbl %>% pull(i)) %in% c("Date", "POSIXct"))) {
|
|
found <- colnames(tbl)[i]
|
|
break
|
|
}
|
|
}
|
|
}
|
|
}
|
|
# -- patient id
|
|
if (type == "patient_id") {
|
|
if (any(colnames(tbl) %like% "^(identification |patient|patid)")) {
|
|
found <- colnames(tbl)[colnames(tbl) %like% "^(identification |patient|patid)"][1]
|
|
}
|
|
}
|
|
# -- specimen
|
|
if (type == "specimen") {
|
|
if (any(colnames(tbl) %like% "(specimen type|spec_type)")) {
|
|
found <- colnames(tbl)[colnames(tbl) %like% "(specimen type|spec_type)"][1]
|
|
} else if (any(colnames(tbl) %like% "^(specimen)")) {
|
|
found <- colnames(tbl)[colnames(tbl) %like% "^(specimen)"][1]
|
|
}
|
|
}
|
|
|
|
if (!is.null(found)) {
|
|
msg <- paste0("NOTE: Using column `", bold(found), "` as input for `col_", type, "`.")
|
|
if (type %in% c("keyantibiotics", "specimen")) {
|
|
msg <- paste(msg, "Use", bold(paste0("col_", type), "= FALSE"), "to prevent this.")
|
|
}
|
|
message(blue(msg))
|
|
}
|
|
found
|
|
}
|
|
|
|
get_column_abx <- function(x,
|
|
soft_dependencies = NULL,
|
|
hard_dependencies = NULL,
|
|
verbose = FALSE,
|
|
...) {
|
|
|
|
# determine from given data set
|
|
df_trans <- data.frame(colnames = colnames(x),
|
|
abcode = suppressWarnings(as.ab(colnames(x))))
|
|
df_trans <- df_trans[!is.na(df_trans$abcode),]
|
|
x <- as.character(df_trans$colnames)
|
|
names(x) <- df_trans$abcode
|
|
|
|
# add from self-defined dots (...):
|
|
# get_column_abx(septic_patients %>% rename(thisone = AMX), amox = "thisone")
|
|
dots <- list(...)
|
|
if (length(dots) > 0) {
|
|
dots <- unlist(dots)
|
|
newnames <- suppressWarnings(as.ab(names(dots)))
|
|
if (any(is.na(newnames))) {
|
|
warning("Invalid antibiotic reference(s): ", toString(names(dots)[is.na(newnames)]),
|
|
call. = FALSE, immediate. = TRUE)
|
|
}
|
|
names(dots) <- newnames
|
|
dots <- dots[!is.na(names(dots))]
|
|
# merge, but overwrite automatically determined ones by 'dots'
|
|
x <- c(x[!x %in% dots & !names(x) %in% names(dots)], dots)
|
|
}
|
|
|
|
# sort on name
|
|
x <- x[sort(names(x))]
|
|
duplies <- x[base::duplicated(x)]
|
|
|
|
if (verbose == TRUE) {
|
|
for (i in 1:length(x)) {
|
|
if (x[i] %in% duplies) {
|
|
message(red(paste0("NOTE: Using column `", bold(x[i]), "` as input for ", names(x)[i],
|
|
" (", ab_name(names(x)[i], language = "en", tolower = TRUE), ") [DUPLICATED USE].")))
|
|
} else {
|
|
message(blue(paste0("NOTE: Using column `", bold(x[i]), "` as input for ", names(x)[i],
|
|
" (", ab_name(names(x)[i], language = "en", tolower = TRUE), ").")))
|
|
}
|
|
}
|
|
}
|
|
|
|
if (n_distinct(x) != length(x)) {
|
|
msg_txt <- paste("Column(s)", paste0("'", duplies, "'", collapse = "'"), "used for more than one antibiotic.")
|
|
if (verbose == FALSE) {
|
|
msg_txt <- paste(msg_txt, "Use verbose = TRUE to see which antibiotics are used by which columns.")
|
|
}
|
|
stop(msg_txt, call. = FALSE)
|
|
}
|
|
|
|
if (!is.null(hard_dependencies)) {
|
|
if (!all(hard_dependencies %in% names(x))) {
|
|
# missing a hard dependency will return NA and consequently the data will not be analysed
|
|
missing <- hard_dependencies[!hard_dependencies %in% names(x)]
|
|
generate_warning_abs_missing(missing, any = FALSE)
|
|
return(NA)
|
|
}
|
|
}
|
|
if (!is.null(soft_dependencies)) {
|
|
if (!all(soft_dependencies %in% names(x))) {
|
|
# missing a soft dependency may lower the reliability
|
|
missing <- soft_dependencies[!soft_dependencies %in% names(x)]
|
|
missing <- paste0("`", missing, "` (", ab_name(missing, tolower = TRUE), ")")
|
|
warning('Reliability might be improved if these antimicrobial results would be available too: ', paste(missing, collapse = ", "),
|
|
immediate. = TRUE,
|
|
call. = FALSE)
|
|
}
|
|
}
|
|
x
|
|
}
|
|
|
|
generate_warning_abs_missing <- function(missing, any = FALSE) {
|
|
missing <- paste0("`", missing, "` (", ab_name(missing, tolower = TRUE), ")")
|
|
if (any == TRUE) {
|
|
any_txt <- c(" any of", "is")
|
|
} else {
|
|
any_txt <- c("", "are")
|
|
}
|
|
warning(paste0("Introducing NAs since", any_txt[1], " these antimicrobials ", any_txt[2], " required: ",
|
|
paste(missing, collapse = ", ")),
|
|
immediate. = TRUE,
|
|
call. = FALSE)
|
|
}
|
|
|
|
|
|
stopifnot_installed_package <- function(package) {
|
|
if (!package %in% base::rownames(utils::installed.packages())) {
|
|
stop("this function requires the ", package, " package.", call. = FALSE)
|
|
}
|
|
}
|
|
|
|
# translate strings based on inst/translations.tsv
|
|
#' @importFrom dplyr %>% filter
|
|
t <- function(from, language = get_locale()) {
|
|
# if (getOption("AMR_locale", "en") != language) {
|
|
# language <- getOption("AMR_locale", "en")
|
|
# }
|
|
|
|
if (is.null(language)) {
|
|
return(from)
|
|
}
|
|
if (language %in% c("en", "")) {
|
|
return(from)
|
|
}
|
|
|
|
df_trans <- utils::read.table(file = system.file("translations.tsv", package = "AMR"),
|
|
sep = "\t",
|
|
stringsAsFactors = FALSE,
|
|
header = TRUE,
|
|
blank.lines.skip = TRUE,
|
|
fill = TRUE,
|
|
strip.white = TRUE,
|
|
encoding = "UTF-8",
|
|
fileEncoding = "UTF-8",
|
|
na.strings = c(NA, "", NULL))
|
|
|
|
if (!language %in% df_trans$lang) {
|
|
stop("Unsupported language: '", language, "' - use one of: ",
|
|
paste0("'", sort(unique(df_trans$lang)), "'", collapse = ", "),
|
|
call. = FALSE)
|
|
}
|
|
|
|
df_trans <- df_trans %>% filter(lang == language)
|
|
|
|
# default case sensitive if value if 'ignore.case' is missing:
|
|
df_trans$ignore.case[is.na(df_trans$ignore.case)] <- FALSE
|
|
# default not using regular expressions (fixed = TRUE) if 'fixed' is missing:
|
|
df_trans$fixed[is.na(df_trans$fixed)] <- TRUE
|
|
|
|
# check if text to look for is in one of the patterns
|
|
any_form_in_patterns <- tryCatch(any(from %like% paste0("(", paste(df_trans$pattern, collapse = "|"), ")")),
|
|
error = function(e) {
|
|
warning("Translation not possible. Please open an issue on GitLab (https://gitlab.com/msberends/AMR/issues) or GitHub (https://github.com/msberends/AMR/issues).", call. = FALSE)
|
|
return(FALSE)
|
|
})
|
|
if (NROW(df_trans) == 0 | !any_form_in_patterns) {
|
|
return(from)
|
|
}
|
|
|
|
for (i in 1:nrow(df_trans)) {
|
|
from <- gsub(x = from,
|
|
pattern = df_trans$pattern[i],
|
|
replacement = df_trans$replacement[i],
|
|
fixed = df_trans$fixed[i],
|
|
ignore.case = df_trans$ignore.case[i])
|
|
}
|
|
|
|
# force UTF-8 for diacritics
|
|
base::enc2utf8(from)
|
|
|
|
}
|
|
|
|
"%or%" <- function(x, y) {
|
|
ifelse(!is.na(x), x, ifelse(!is.na(y), y, NA))
|
|
}
|