mirror of
https://github.com/msberends/AMR.git
synced 2024-12-25 18:46:11 +01:00
204 lines
7.4 KiB
R
204 lines
7.4 KiB
R
# ==================================================================== #
|
|
# TITLE #
|
|
# Antimicrobial Resistance (AMR) Data Analysis for R #
|
|
# #
|
|
# SOURCE #
|
|
# https://github.com/msberends/AMR #
|
|
# #
|
|
# LICENCE #
|
|
# (c) 2018-2021 Berends MS, Luz CF et al. #
|
|
# Developed at the University of Groningen, the Netherlands, in #
|
|
# collaboration with non-profit organisations Certe Medical #
|
|
# Diagnostics & Advice, and University Medical Center Groningen. #
|
|
# #
|
|
# This R package is free software; you can freely use and distribute #
|
|
# it for both personal and commercial purposes under the terms of the #
|
|
# GNU General Public License version 2.0 (GNU GPL-2), as published by #
|
|
# the Free Software Foundation. #
|
|
# We created this package for both routine data analysis and academic #
|
|
# research and it was publicly released in the hope that it will be #
|
|
# useful, but it comes WITHOUT ANY WARRANTY OR LIABILITY. #
|
|
# #
|
|
# Visit our website for the full manual and a complete tutorial about #
|
|
# how to conduct AMR data analysis: https://msberends.github.io/AMR/ #
|
|
# ==================================================================== #
|
|
|
|
#' Create Identifier of an Isolate
|
|
#'
|
|
#' This function will paste the microorganism code with all antimicrobial results into one string for each row in a data set. This is useful to compare isolates, e.g. between institutions or regions, when there is no genotyping available.
|
|
#' @inheritSection lifecycle Experimental Lifecycle
|
|
#' @inheritParams eucast_rules
|
|
#' @param cols_ab a character vector of column names of `x`, or (a combination with) an [antibiotic selector function]([ab_class()]), such as [carbapenems()] and [aminoglycosides()]
|
|
#' @rdname isolate_identifier
|
|
#' @export
|
|
#' @inheritSection AMR Read more on Our Website!
|
|
#' @examples
|
|
#' # automatic selection of microorganism and antibiotics (i.e., all <rsi> columns, see ?as.rsi)
|
|
#' x <- isolate_identifier(example_isolates)
|
|
#'
|
|
#' # ignore microorganism codes, only use antimicrobial results
|
|
#' x <- isolate_identifier(example_isolates, col_mo = FALSE, cols_ab = c("AMX", "TZP", "GEN", "TOB"))
|
|
#'
|
|
#' # select antibiotics from certain antibiotic classes
|
|
#' x <- isolate_identifier(example_isolates, cols_ab = c(carbapenems(), aminoglycosides()))
|
|
isolate_identifier <- function(x, col_mo = NULL, cols_ab = NULL) {
|
|
if (is.null(col_mo)) {
|
|
col_mo <- search_type_in_df(x, "mo")
|
|
if (is.null(col_mo)) {
|
|
# no column found, then ignore the argument
|
|
col_mo <- FALSE
|
|
}
|
|
}
|
|
|
|
if (isFALSE(col_mo)) {
|
|
# is FALSE then ignore mo column
|
|
x$col_mo <- ""
|
|
col_mo <- "col_mo"
|
|
} else if (!is.null(col_mo)) {
|
|
x[, col_mo] <- paste0(as.mo(x[, col_mo, drop = TRUE]), "|")
|
|
}
|
|
|
|
cols_ab <- deparse(substitute(cols_ab)) # support ab class selectors: isolate_identifier(x, cols_ab = carbapenems())
|
|
if (identical(cols_ab, "NULL")) {
|
|
cols_ab <- colnames(x)[vapply(FUN.VALUE = logical(1), x, is.rsi)]
|
|
} else {
|
|
cols_ab <- tryCatch(colnames(x[, eval(parse(text = cols_ab), envir = parent.frame())]),
|
|
# tryCatch adds 4 calls, so total is -5
|
|
error = function(e) stop_(e$message, call = -5))
|
|
}
|
|
|
|
# cope with empty values
|
|
if (length(cols_ab) == 0 && all(x[, col_mo, drop = TRUE] == "", na.rm = TRUE)) {
|
|
warning_("in isolate_identifier(): no column with microorganisms and no columns with antimicrobial agents found", call = FALSE)
|
|
} else if (length(cols_ab) == 0) {
|
|
warning_("in isolate_identifier(): no columns with antimicrobial agents found", call = FALSE)
|
|
}
|
|
|
|
out <- x[, c(col_mo, cols_ab), drop = FALSE]
|
|
out <- do.call(paste, c(out, sep = ""))
|
|
out <- gsub("NA", ".", out, fixed = TRUE)
|
|
out <- set_clean_class(out, new_class = c("isolate_identifier", "character"))
|
|
attr(out, "ab") <- cols_ab
|
|
out
|
|
}
|
|
|
|
#' @method all.equal isolate_identifier
|
|
#' @inheritParams base::all.equal
|
|
#' @param ignore_empty_results a logical to indicate whether empty results must be ignored, so that only values R, S and I will be compared
|
|
#' @rdname isolate_identifier
|
|
#' @export
|
|
all.equal.isolate_identifier <- function(target, current, ignore_empty_results = TRUE, ...) {
|
|
meet_criteria(target, allow_class = "isolate_identifier")
|
|
meet_criteria(current, allow_class = "isolate_identifier")
|
|
meet_criteria(ignore_empty_results, allow_class = "logical", has_length = 1)
|
|
|
|
if (isTRUE(all.equal.character(target, current))) {
|
|
return(TRUE)
|
|
}
|
|
# vectorise over both target and current
|
|
if (length(target) > 1 && length(current) == 1) {
|
|
current <- rep(current, length(target))
|
|
} else if (length(current) > 1 && length(target) == 1) {
|
|
target <- rep(target, length(current))
|
|
}
|
|
stop_if(length(target) != length(current),
|
|
"length of `target` and `current` must be the same, or one must be 1")
|
|
|
|
get_vector <- function(x) {
|
|
if (grepl("|", x, fixed = TRUE)) {
|
|
mo <- gsub("(.*)\\|.*", "\\1", x)
|
|
} else {
|
|
mo <- NULL
|
|
}
|
|
if (grepl("|", x, fixed = TRUE)) {
|
|
ab <- gsub(".*\\|(.*)", "\\1", x)
|
|
} else {
|
|
ab <- x
|
|
}
|
|
ab <- strsplit(ab, "")[[1L]]
|
|
if (is.null(mo)) {
|
|
out <- as.character(ab)
|
|
names(out) <- attributes(x)$ab
|
|
} else {
|
|
out <- as.character(c(mo, ab))
|
|
names(out) <- c("mo", attributes(x)$ab)
|
|
}
|
|
out
|
|
}
|
|
|
|
# run it
|
|
for (i in seq_len(length(target))) {
|
|
if (i == 1) {
|
|
df <- data.frame(object = paste0(c("target[", "current["), i, "]"))
|
|
}
|
|
trgt <- get_vector(target[i])
|
|
crnt <- get_vector(current[i])
|
|
if (ignore_empty_results == TRUE) {
|
|
diff <- names(trgt[trgt != crnt & trgt != "." & crnt != "."])
|
|
} else {
|
|
diff <- names(trgt[trgt != crnt])
|
|
}
|
|
|
|
}
|
|
|
|
stop("THIS FUNCTION IS WORK IN PROGRESS AND NOT AVAILABLE IN THIS BETA VERSION")
|
|
|
|
}
|
|
|
|
#' @method print isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
print.isolate_identifier <- function(x, ...) {
|
|
print(as.character(x), ...)
|
|
}
|
|
|
|
#' @method [ isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
"[.isolate_identifier" <- function(x, ...) {
|
|
y <- NextMethod()
|
|
attributes(y) <- attributes(x)
|
|
y
|
|
}
|
|
#' @method [[ isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
"[[.isolate_identifier" <- function(x, ...) {
|
|
y <- NextMethod()
|
|
attributes(y) <- attributes(x)
|
|
y
|
|
}
|
|
#' @method [<- isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
"[<-.isolate_identifier" <- function(i, j, ..., value) {
|
|
y <- NextMethod()
|
|
attributes(y) <- attributes(i)
|
|
y
|
|
}
|
|
#' @method [[<- isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
"[[<-.isolate_identifier" <- function(i, j, ..., value) {
|
|
y <- NextMethod()
|
|
attributes(y) <- attributes(i)
|
|
y
|
|
}
|
|
#' @method c isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
c.isolate_identifier <- function(x, ...) {
|
|
y <- NextMethod()
|
|
attributes(y) <- attributes(x)
|
|
y
|
|
}
|
|
|
|
#' @method unique isolate_identifier
|
|
#' @export
|
|
#' @noRd
|
|
unique.isolate_identifier <- function(x, incomparables = FALSE, ...) {
|
|
y <- NextMethod()
|
|
attributes(y) <- attributes(x)
|
|
y
|
|
}
|