mirror of https://github.com/msberends/AMR.git
207 lines
8.2 KiB
R
207 lines
8.2 KiB
R
# ==================================================================== #
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# TITLE #
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# Antimicrobial Resistance (AMR) Analysis #
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# #
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# SOURCE #
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# https://gitlab.com/msberends/AMR #
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# #
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# LICENCE #
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# (c) 2019 Berends MS (m.s.berends@umcg.nl), Luz CF (c.f.luz@umcg.nl) #
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# #
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# This R package is free software; you can freely use and distribute #
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# it for both personal and commercial purposes under the terms of the #
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# GNU General Public License version 2.0 (GNU GPL-2), as published by #
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# the Free Software Foundation. #
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# #
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# This R package was created for academic research and was publicly #
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# released in the hope that it will be useful, but it comes WITHOUT #
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# ANY WARRANTY OR LIABILITY. #
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# Visit our website for more info: https://msberends.gitlab.io/AMR. #
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# ==================================================================== #
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#' Property of an antibiotic
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#'
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#' Use these functions to return a specific property of an antibiotic from the \code{\link{antibiotics}} data set. All input values will be evaluated internally with \code{\link{as.ab}}.
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#' @param x any (vector of) text that can be coerced to a valid microorganism code with \code{\link{as.ab}}
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#' @param tolower logical to indicate whether the first character of every output should be transformed to a lower case character. This will lead to e.g. "polymyxin B" and not "polymyxin b".
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#' @param property one of the column names of one of the \code{\link{antibiotics}} data set
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#' @param language language of the returned text, defaults to system language (see \code{\link{get_locale}}) and can also be set with \code{\link{getOption}("AMR_locale")}. Use \code{language = NULL} or \code{language = ""} to prevent translation.
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#' @param administration way of administration, either \code{"oral"} or \code{"iv"}
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#' @param units a logical to indicate whether the units instead of the DDDs itself must be returned, see Examples
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#' @param ... other parameters passed on to \code{\link{as.ab}}
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#' @details All output will be \link{translate}d where possible.
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#' @inheritSection as.ab Source
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#' @rdname ab_property
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#' @name ab_property
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#' @return \itemize{
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#' \item{An \code{integer} in case of \code{ab_cid}}
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#' \item{A named \code{list} in case of \code{ab_info} and multiple \code{ab_synonyms}/\code{ab_tradenames}}
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#' \item{A \code{double} in case of \code{ab_ddd}}
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#' \item{A \code{character} in all other cases}
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#' }
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#' @export
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#' @seealso \code{\link{antibiotics}}
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#' @inheritSection AMR Read more on our website!
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#' @examples
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#' # all properties:
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#' ab_name("AMX") # "Amoxicillin"
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#' ab_atc("AMX") # J01CA04 (ATC code from the WHO)
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#' ab_cid("AMX") # 33613 (Compound ID from PubChem)
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#'
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#' ab_synonyms("AMX") # a list with brand names of amoxicillin
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#' ab_tradenames("AMX") # same
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#'
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#' ab_group("AMX") # "Beta-lactams/penicillins"
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#' ab_atc_group1("AMX") # "Beta-lactam antibacterials, penicillins"
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#' ab_atc_group2("AMX") # "Penicillins with extended spectrum"
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#'
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#' ab_name(x = c("AMC", "PLB")) # "Amoxicillin/clavulanic acid" "Polymyxin B"
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#' ab_name(x = c("AMC", "PLB"),
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#' tolower = TRUE) # "amoxicillin/clavulanic acid" "polymyxin B"
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#'
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#' ab_ddd("AMX", "oral") # 1
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#' ab_ddd("AMX", "oral", units = TRUE) # "g"
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#' ab_ddd("AMX", "iv") # 1
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#' ab_ddd("AMX", "iv", units = TRUE) # "g"
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#'
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#' ab_info("AMX") # all properties as a list
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#'
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#' # all ab_* functions use as.ab() internally:
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#' ab_name("Fluclox") # "Flucloxacillin"
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#' ab_name("fluklox") # "Flucloxacillin"
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#' ab_name("floxapen") # "Flucloxacillin"
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#' ab_name(21319) # "Flucloxacillin" (using CID)
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#' ab_name("J01CF05") # "Flucloxacillin" (using ATC)
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ab_name <- function(x, language = get_locale(), tolower = FALSE, ...) {
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x <- translate_AMR(ab_validate(x = x, property = "name", ...), language = language)
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if (tolower == TRUE) {
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# use perl to only transform the first character
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# as we want "polymyxin B", not "polymyxin b"
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x <- gsub("^([A-Z])", "\\L\\1", x, perl = TRUE)
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}
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x
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}
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#' @rdname ab_property
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#' @export
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ab_atc <- function(x, ...) {
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ab_validate(x = x, property = "atc", ...)
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}
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#' @rdname ab_property
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#' @export
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ab_cid <- function(x, ...) {
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ab_validate(x = x, property = "cid", ...)
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}
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#' @rdname ab_property
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#' @export
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ab_synonyms <- function(x, ...) {
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syns <- ab_validate(x = x, property = "synonyms", ...)
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names(syns) <- x
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if (length(syns) == 1) {
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unname(unlist(syns))
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} else {
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syns
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}
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}
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#' @rdname ab_property
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#' @export
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ab_tradenames <- function(x, ...) {
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ab_synonyms(x, ...)
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}
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#' @rdname ab_property
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#' @export
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ab_group <- function(x, language = get_locale(), ...) {
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translate_AMR(ab_validate(x = x, property = "group", ...), language = language)
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}
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#' @rdname ab_property
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#' @export
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ab_atc_group1 <- function(x, language = get_locale(), ...) {
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translate_AMR(ab_validate(x = x, property = "atc_group1", ...), language = language)
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}
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#' @rdname ab_property
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#' @export
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ab_atc_group2 <- function(x, language = get_locale(), ...) {
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translate_AMR(ab_validate(x = x, property = "atc_group2", ...), language = language)
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}
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#' @rdname ab_property
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#' @export
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ab_ddd <- function(x, administration = "oral", units = FALSE, ...) {
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if (!administration %in% c("oral", "iv")) {
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stop("`administration` must be 'oral' or 'iv'", call. = FALSE)
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}
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ddd_prop <- administration
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if (units == TRUE) {
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ddd_prop <- paste0(ddd_prop, "_units")
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} else {
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ddd_prop <- paste0(ddd_prop, "_ddd")
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}
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ab_validate(x = x, property = ddd_prop, ...)
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}
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#' @rdname ab_property
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#' @export
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ab_info <- function(x, language = get_locale(), ...) {
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x <- AMR::as.ab(x, ...)
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base::list(ab = as.character(x),
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atc = ab_atc(x),
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cid = ab_cid(x),
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name = ab_name(x, language = language),
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group = ab_group(x, language = language),
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atc_group1 = ab_atc_group1(x, language = language),
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atc_group2 = ab_atc_group2(x, language = language),
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tradenames = ab_tradenames(x),
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ddd = list(oral = list(amount = ab_ddd(x, administration = "oral", units = FALSE),
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units = ab_ddd(x, administration = "oral", units = TRUE)),
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iv = list(amount = ab_ddd(x, administration = "iv", units = FALSE),
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units = ab_ddd(x, administration = "iv", units = TRUE))))
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}
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#' @rdname ab_property
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#' @export
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ab_property <- function(x, property = "name", language = get_locale(), ...) {
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if (length(property) != 1L) {
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stop("'property' must be of length 1.")
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}
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if (!property %in% colnames(AMR::antibiotics)) {
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stop("invalid property: '", property, "' - use a column name of the `antibiotics` data set")
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}
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translate_AMR(ab_validate(x = x, property = property, ...), language = language)
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}
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ab_validate <- function(x, property, ...) {
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if (!"AMR" %in% base::.packages()) {
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library("AMR")
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# check onLoad() in R/zzz.R: data tables are created there.
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}
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# try to catch an error when inputting an invalid parameter
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# so the 'call.' can be set to FALSE
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tryCatch(x[1L] %in% AMR::antibiotics[1, property],
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error = function(e) stop(e$message, call. = FALSE))
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x_bak <- x
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if (!all(x %in% AMR::antibiotics[, property])) {
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x <- data.frame(ab = AMR::as.ab(x, ...), stringsAsFactors = FALSE) %>%
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left_join(AMR::antibiotics, by = "ab") %>%
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pull(property)
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}
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if (property == "ab") {
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return(structure(x, class = property))
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} else if (property == "cid") {
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return(as.integer(x))
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} else if (property %like% "ddd") {
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return(as.double(x))
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} else {
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# return "(input)" for NAs
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x[is.na(x) & !is.na(x_bak)] <- paste0("(", x_bak[is.na(x) & !is.na(x_bak)], ")")
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return(x)
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}
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}
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