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<img src="../logo.svg" class="logo" alt=""><h1>Transform Input to an Antiviral Drug ID</h1>
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<small class="dont-index">Source: <a href="https://github.com/msberends/AMR/blob/HEAD/R/av.R" class="external-link"><code>R/av.R</code></a></small>
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<div class="d-none name"><code>as.av.Rd</code></div>
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<div class="ref-description section level2">
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<p>Use this function to determine the antiviral drug code of one or more antiviral drugs. The data set <a href="antibiotics.html">antivirals</a> will be searched for abbreviations, official names and synonyms (brand names).</p>
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</div>
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<div class="section level2">
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<h2 id="ref-usage">Usage<a class="anchor" aria-label="anchor" href="#ref-usage"></a></h2>
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<div class="sourceCode"><pre class="sourceCode r"><code><span><span class="fu">as.av</span><span class="op">(</span><span class="va">x</span>, flag_multiple_results <span class="op">=</span> <span class="cn">TRUE</span>, info <span class="op">=</span> <span class="fu"><a href="https://rdrr.io/r/base/interactive.html" class="external-link">interactive</a></span><span class="op">(</span><span class="op">)</span>, <span class="va">...</span><span class="op">)</span></span>
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<span></span>
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<span><span class="fu">is.av</span><span class="op">(</span><span class="va">x</span><span class="op">)</span></span></code></pre></div>
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</div>
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<div class="section level2">
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<h2 id="arguments">Arguments<a class="anchor" aria-label="anchor" href="#arguments"></a></h2>
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<dl><dt>x</dt>
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<dd><p>a <a href="https://rdrr.io/r/base/character.html" class="external-link">character</a> vector to determine to antiviral drug ID</p></dd>
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<dt>flag_multiple_results</dt>
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<dd><p>a <a href="https://rdrr.io/r/base/logical.html" class="external-link">logical</a> to indicate whether a note should be printed to the console that probably more than one antiviral drug code or name can be retrieved from a single input value.</p></dd>
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<dt>info</dt>
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<dd><p>a <a href="https://rdrr.io/r/base/logical.html" class="external-link">logical</a> to indicate whether a progress bar should be printed, defaults to <code>TRUE</code> only in interactive mode</p></dd>
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<dt>...</dt>
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<dd><p>arguments passed on to internal functions</p></dd>
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</dl></div>
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<div class="section level2">
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<h2 id="value">Value<a class="anchor" aria-label="anchor" href="#value"></a></h2>
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<p>A <a href="https://rdrr.io/r/base/character.html" class="external-link">character</a></p>
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<p></p>
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<p><a href="https://rdrr.io/r/base/vector.html" class="external-link">vector</a> with additional class <code><a href="as.ab.html">ab</a></code></p>
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</div>
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<div class="section level2">
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<h2 id="details">Details<a class="anchor" aria-label="anchor" href="#details"></a></h2>
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<p>All entries in the <a href="antibiotics.html">antivirals</a> data set have three different identifiers: a human readable EARS-Net code (column <code>ab</code>, used by ECDC and WHONET), an ATC code (column <code>atc</code>, used by WHO), and a CID code (column <code>cid</code>, Compound ID, used by PubChem). The data set contains more than 5,000 official brand names from many different countries, as found in PubChem. Not that some drugs contain multiple ATC codes.</p>
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<p>All these properties will be searched for the user input. The <code>as.av()</code> can correct for different forms of misspelling:</p><ul><li><p>Wrong spelling of drug names (such as "acyclovir"), which corrects for most audible similarities such as f/ph, x/ks, c/z/s, t/th, etc.</p></li>
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<li><p>Too few or too many vowels or consonants</p></li>
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<li><p>Switching two characters (such as "aycclovir", often the case in clinical data, when doctors typed too fast)</p></li>
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<li><p>Digitalised paper records, leaving artefacts like 0/o/O (zero and O's), B/8, n/r, etc.</p></li>
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</ul><p>Use the <code><a href="av_property.html">av_*</a></code> functions to get properties based on the returned antiviral drug ID, see <em>Examples</em>.</p>
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<p>Note: the <code>as.av()</code> and <code><a href="av_property.html">av_*</a></code> functions may use very long regular expression to match brand names of antimicrobial drugs. This may fail on some systems.</p>
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</div>
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<div class="section level2">
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<h2 id="source">Source<a class="anchor" aria-label="anchor" href="#source"></a></h2>
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<p>World Health Organization (WHO) Collaborating Centre for Drug Statistics Methodology: <a href="https://www.whocc.no/atc_ddd_index/" class="external-link">https://www.whocc.no/atc_ddd_index/</a></p>
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<p>European Commission Public Health PHARMACEUTICALS - COMMUNITY REGISTER: <a href="https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm" class="external-link">https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm</a></p>
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</div>
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<div class="section level2">
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<h2 id="whocc">WHOCC<a class="anchor" aria-label="anchor" href="#whocc"></a></h2>
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<p>This package contains <strong>all ~550 antibiotic, antimycotic and antiviral drugs</strong> and their Anatomical Therapeutic Chemical (ATC) codes, ATC groups and Defined Daily Dose (DDD) from the World Health Organization Collaborating Centre for Drug Statistics Methodology (WHOCC, <a href="https://www.whocc.no" class="external-link">https://www.whocc.no</a>) and the Pharmaceuticals Community Register of the European Commission (<a href="https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm" class="external-link">https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm</a>).</p>
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<p>These have become the gold standard for international drug utilisation monitoring and research.</p>
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<p>The WHOCC is located in Oslo at the Norwegian Institute of Public Health and funded by the Norwegian government. The European Commission is the executive of the European Union and promotes its general interest.</p>
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<p><strong>NOTE: The WHOCC copyright does not allow use for commercial purposes, unlike any other info from this package.</strong> See <a href="https://www.whocc.no/copyright_disclaimer/." class="external-link">https://www.whocc.no/copyright_disclaimer/.</a></p>
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</div>
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<div class="section level2">
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<h2 id="reference-data-publicly-available">Reference Data Publicly Available<a class="anchor" aria-label="anchor" href="#reference-data-publicly-available"></a></h2>
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<p>All data sets in this <code>AMR</code> package (about microorganisms, antibiotics, R/SI interpretation, EUCAST rules, etc.) are publicly and freely available for download in the following formats: R, MS Excel, Apache Feather, Apache Parquet, SPSS, SAS, and Stata. We also provide tab-separated plain text files that are machine-readable and suitable for input in any software program, such as laboratory information systems. Please visit <a href="https://msberends.github.io/AMR/articles/datasets.html">our website for the download links</a>. The actual files are of course available on <a href="https://github.com/msberends/AMR/tree/main/data-raw" class="external-link">our GitHub repository</a>.</p>
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</div>
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<div class="section level2">
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<h2 id="see-also">See also<a class="anchor" aria-label="anchor" href="#see-also"></a></h2>
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<div class="dont-index">
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<ul><li><p><a href="antibiotics.html">antivirals</a> for the <a href="https://rdrr.io/r/base/data.frame.html" class="external-link">data.frame</a> that is being used to determine ATCs</p></li>
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<li><p><code><a href="av_from_text.html">av_from_text()</a></code> for a function to retrieve antimicrobial drugs from clinical text (from health care records)</p></li>
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</ul></div>
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</div>
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<div class="section level2">
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<h2 id="ref-examples">Examples<a class="anchor" aria-label="anchor" href="#ref-examples"></a></h2>
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<div class="sourceCode"><pre class="sourceCode r"><code><span class="r-in"><span><span class="co"># these examples all return "ACI", the ID of aciclovir:</span></span></span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"J05AB01"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"J 05 AB 01"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"Aciclovir"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"aciclo"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">" aciclo 123"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"ACICL"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"ACI"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"Virorax"</span><span class="op">)</span> <span class="co"># trade name</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"Zovirax"</span><span class="op">)</span> <span class="co"># trade name</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span></span></span>
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<span class="r-in"><span><span class="fu">as.av</span><span class="op">(</span><span class="st">"acyklofir"</span><span class="op">)</span> <span class="co"># severe spelling error, yet works</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> Class 'av'</span>
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<span class="r-out co"><span class="r-pr">#></span> [1] ACI</span>
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<span class="r-in"><span></span></span>
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<span class="r-in"><span><span class="co"># use av_* functions to get a specific properties (see ?av_property);</span></span></span>
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<span class="r-in"><span><span class="co"># they use as.av() internally:</span></span></span>
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<span class="r-in"><span><span class="fu"><a href="av_property.html">av_name</a></span><span class="op">(</span><span class="st">"J05AB01"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> [1] "Aciclovir"</span>
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<span class="r-in"><span><span class="fu"><a href="av_property.html">av_name</a></span><span class="op">(</span><span class="st">"acicl"</span><span class="op">)</span></span></span>
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<span class="r-out co"><span class="r-pr">#></span> [1] "Aciclovir"</span>
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</code></pre></div>
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