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139 lines
6.5 KiB
R
139 lines
6.5 KiB
R
% Generated by roxygen2: do not edit by hand
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% Please edit documentation in R/resistance_predict.R
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\name{resistance_predict}
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\alias{resistance_predict}
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\alias{sir_predict}
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\alias{plot.resistance_predict}
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\alias{ggplot_sir_predict}
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\alias{autoplot.resistance_predict}
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\title{Predict Antimicrobial Resistance}
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\usage{
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resistance_predict(x, col_ab, col_date = NULL, year_min = NULL,
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year_max = NULL, year_every = 1, minimum = 30, model = NULL,
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I_as_S = TRUE, preserve_measurements = TRUE, info = interactive(), ...)
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sir_predict(x, col_ab, col_date = NULL, year_min = NULL, year_max = NULL,
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year_every = 1, minimum = 30, model = NULL, I_as_S = TRUE,
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preserve_measurements = TRUE, info = interactive(), ...)
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\method{plot}{resistance_predict}(x, main = paste("Resistance Prediction of",
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x_name), ...)
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ggplot_sir_predict(x, main = paste("Resistance Prediction of", x_name),
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ribbon = TRUE, ...)
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\method{autoplot}{resistance_predict}(object,
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main = paste("Resistance Prediction of", x_name), ribbon = TRUE, ...)
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}
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\arguments{
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\item{x}{A \link{data.frame} containing isolates. Can be left blank for automatic determination, see \emph{Examples}.}
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\item{col_ab}{Column name of \code{x} containing antimicrobial interpretations (\code{"R"}, \code{"I"} and \code{"S"}).}
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\item{col_date}{Column name of the date, will be used to calculate years if this column doesn't consist of years already - the default is the first column of with a date class.}
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\item{year_min}{Lowest year to use in the prediction model, dafaults to the lowest year in \code{col_date}.}
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\item{year_max}{Highest year to use in the prediction model - the default is 10 years after today.}
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\item{year_every}{Unit of sequence between lowest year found in the data and \code{year_max}.}
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\item{minimum}{Minimal amount of available isolates per year to include. Years containing less observations will be estimated by the model.}
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\item{model}{The statistical model of choice. This could be a generalised linear regression model with binomial distribution (i.e. using \code{glm(..., family = binomial)}, assuming that a period of zero resistance was followed by a period of increasing resistance leading slowly to more and more resistance. See \emph{Details} for all valid options.}
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\item{I_as_S}{A \link{logical} to indicate whether values \code{"I"} should be treated as \code{"S"} (will otherwise be treated as \code{"R"}). The default, \code{TRUE}, follows the redefinition by EUCAST about the interpretation of I (increased exposure) in 2019, see section \emph{Interpretation of S, I and R} below.}
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\item{preserve_measurements}{A \link{logical} to indicate whether predictions of years that are actually available in the data should be overwritten by the original data. The standard errors of those years will be \code{NA}.}
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\item{info}{A \link{logical} to indicate whether textual analysis should be printed with the name and \code{\link[=summary]{summary()}} of the statistical model.}
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\item{...}{Arguments passed on to functions.}
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\item{main}{Title of the plot.}
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\item{ribbon}{A \link{logical} to indicate whether a ribbon should be shown (default) or error bars.}
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\item{object}{Model data to be plotted.}
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}
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\value{
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A \link{data.frame} with extra class \code{\link{resistance_predict}} with columns:
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\itemize{
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\item \code{year}
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\item \code{value}, the same as \code{estimated} when \code{preserve_measurements = FALSE}, and a combination of \code{observed} and \code{estimated} otherwise
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\item \code{se_min}, the lower bound of the standard error with a minimum of \code{0} (so the standard error will never go below 0\%)
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\item \code{se_max} the upper bound of the standard error with a maximum of \code{1} (so the standard error will never go above 100\%)
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\item \code{observations}, the total number of available observations in that year, i.e. \eqn{S + I + R}
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\item \code{observed}, the original observed resistant percentages
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\item \code{estimated}, the estimated resistant percentages, calculated by the model
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}
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Furthermore, the model itself is available as an attribute: \code{attributes(x)$model}, see \emph{Examples}.
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}
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\description{
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Create a prediction model to predict antimicrobial resistance for the next years. Standard errors (SE) will be returned as columns \code{se_min} and \code{se_max}. See \emph{Examples} for a real live example.
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\strong{NOTE:} These functions are \link[=AMR-deprecated]{deprecated} and will be removed in a future version. Use the AMR package combined with the tidymodels framework instead, for which we have written a \href{https://amr-for-r.org/articles/AMR_with_tidymodels.html}{basic and short introduction on our website}.
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}
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\details{
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Valid options for the statistical model (argument \code{model}) are:
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\itemize{
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\item \code{"binomial"} or \code{"binom"} or \code{"logit"}: a generalised linear regression model with binomial distribution
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\item \code{"loglin"} or \code{"poisson"}: a generalised log-linear regression model with poisson distribution
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\item \code{"lin"} or \code{"linear"}: a linear regression model
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}
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}
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\section{Interpretation of SIR}{
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In 2019, the European Committee on Antimicrobial Susceptibility Testing (EUCAST) has decided to change the definitions of susceptibility testing categories S, I, and R (\url{https://www.eucast.org/newsiandr}).
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This AMR package follows insight; use \code{\link[=susceptibility]{susceptibility()}} (equal to \code{\link[=proportion_SI]{proportion_SI()}}) to determine antimicrobial susceptibility and \code{\link[=count_susceptible]{count_susceptible()}} (equal to \code{\link[=count_SI]{count_SI()}}) to count susceptible isolates.
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}
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\examples{
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x <- resistance_predict(example_isolates,
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col_ab = "AMX",
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year_min = 2010,
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model = "binomial"
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)
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plot(x)
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\donttest{
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if (require("ggplot2")) {
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ggplot_sir_predict(x)
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}
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# using dplyr:
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if (require("dplyr")) {
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x <- example_isolates \%>\%
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filter_first_isolate() \%>\%
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filter(mo_genus(mo) == "Staphylococcus") \%>\%
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resistance_predict("PEN", model = "binomial")
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print(plot(x))
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# get the model from the object
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mymodel <- attributes(x)$model
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summary(mymodel)
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}
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# create nice plots with ggplot2 yourself
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if (require("dplyr") && require("ggplot2")) {
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data <- example_isolates \%>\%
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filter(mo == as.mo("E. coli")) \%>\%
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resistance_predict(
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col_ab = "AMX",
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col_date = "date",
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model = "binomial",
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info = FALSE,
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minimum = 15
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)
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head(data)
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autoplot(data)
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}
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}
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}
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\seealso{
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The \code{\link[=proportion]{proportion()}} functions to calculate resistance
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Models: \code{\link[=lm]{lm()}} \code{\link[=glm]{glm()}}
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}
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