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ch01-introduction
microbial-epidemiology
antimicrobial-resistance-in-microorganisms
laboratory-diagnostics
interpretation-of-raw-results
multi-drug-resistant-organisms
surveillance-programs
data-analysis-using-r
setting-for-this-thesis
aim-of-this-thesis-and-introduction-to-its-chapters
ch02-diagnostic-stewardship
introduction
case-1
case-2
the-general-concept
diagnostics
dsp-in-the-microbiological-laboratory
dsp-as-process-optimisation
multidisciplinary-aspects-of-dsp-and-infection-management
conclusion
ch03-introducing-new-method
background
standardising-amr-data-analysis
comparison-with-existing-software-methods
user-feedback
conclusion-1
ch04-amr-r-package
introduction-1
antimicrobial-resistance-data
antimicrobial-resistance-data-transformation
working-with-taxonomically-valid-microorganism-names
properties-of-microorganisms
working-with-antimicrobial-names-or-codes
properties-of-antimicrobial-agents
filtering-data-based-on-classes-of-antimicrobial-agents
working-with-antimicrobial-susceptibility-test-results
interpretative-rules-by-eucast
working-with-defined-daily-doses-ddd
enhancing-antimicrobial-resistance-data
determining-first-isolates
determining-multi-drug-resistant-organisms-mdro
multi-drug-resistant-tuberculosis
analysing-antimicrobial-resistance-data
calculation-of-antimicrobial-resistance
counts
proportions
design-decisions
reproducible-example
discussion
ch05-radar
introduction-2
background-1
objectives
methods
results
overview
application-design
development-process
workflow
customisation
discussion-1
principal-findings
conclusions
ch06-radar2
introduction-3
methods-1
study-setup
amr-data
amr-data-analysis-and-reporting
study-participants
study-execution-and-data
evaluation-and-study-data-analysis
results-1
study-participants-1
effectiveness-and-accuracy
efficiency
satisfaction
discussion-2
ch07-cons
introduction-4
materials-methods
study-setting-and-patient-cohort
microbiological-and-demographic-data
species-determination-and-antibiotic-susceptibility-testing-ast
selection-of-bacterial-isolates
eucast-rules-and-antibiotic-resistance-analysis
statistical-analysis
ethical-considerations
results-2
patients-and-included-isolates
occurrence-of-cons-species
definition-of-cons-persistence
antibiotic-resistance-analysis
glycopeptides
macrolides
fluoroquinolones
beta-lactamspenicillins
other-antibiotics
other-relevant-species
effect-of-patient-age-groups-on-antibiotic-resistance-in-cons
discussion-3
ch08-defining-mdr
introduction-5
methods-2
results-3
number-of-antibiograms-and-patients
results-of-mrgn-and-brmo-classification
discussion-4
ch09-changing-epidemiology
introduction-6
methods-3
setting
guidelines-for-patients-at-risk-for-mrsa-and-infection-prevention-and-control-measures
data-collection
ethical-statement
data-analysis
results-4
trend-and-cross-border-comparison-of-mrsa-rates
cross-border-comparison-of-healthcare-utilisation
discussion-5
ch10-multi-mdro-screening
introduction-7
methods-4
study-design
statistical-analysis-software
ethics
results-5
healthcare-structure-of-the-participating-hospitals
study-population-and-screening-samples-from-icus
prevalence-of-gram-positive-mdros-mrsa-and-vre
prevalence-of-gram-negative-mdro-3gcre-and-cre
prevalence-of-gram-negative-mdros-based-on-dutch-and-german-definitions
comparison-of-mdro-prevalence-between-nl-br-and-de-br-icus-in-university-and-non-university-hospitals
discussion-6
ch11-summary