AMR/R/atc_online.R

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# ==================================================================== #
# TITLE #
# Antimicrobial Resistance (AMR) Analysis #
# #
# SOURCE #
# https://gitlab.com/msberends/AMR #
# #
# LICENCE #
# (c) 2018-2020 Berends MS, Luz CF et al. #
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# #
# This R package is free software; you can freely use and distribute #
# it for both personal and commercial purposes under the terms of the #
# GNU General Public License version 2.0 (GNU GPL-2), as published by #
# the Free Software Foundation. #
# #
# We created this package for both routine data analysis and academic #
# research and it was publicly released in the hope that it will be #
# useful, but it comes WITHOUT ANY WARRANTY OR LIABILITY. #
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# Visit our website for more info: https://msberends.gitlab.io/AMR. #
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# ==================================================================== #
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#' Get ATC properties from WHOCC website
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#'
#' @inheritSection lifecycle Questioning lifecycle
#' @description Gets data from the WHO to determine properties of an ATC (e.g. an antibiotic) like name, defined daily dose (DDD) or standard unit.
#'
#' **This function requires an internet connection.**
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#' @param atc_code a character or character vector with ATC code(s) of antibiotic(s)
#' @param property property of an ATC code. Valid values are `"ATC"`, `"Name"`, `"DDD"`, `"U"` (`"unit"`), `"Adm.R"`, `"Note"` and `groups`. For this last option, all hierarchical groups of an ATC code will be returned, see Examples.
#' @param administration type of administration when using `property = "Adm.R"`, see Details
#' @param url url of website of the WHO. The sign `%s` can be used as a placeholder for ATC codes.
#' @param ... parameters to pass on to `atc_property`
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#' @details
#' Options for parameter `administration`:
#'
#' - `"Implant"` = Implant
#' - `"Inhal"` = Inhalation
#' - `"Instill"` = Instillation
#' - `"N"` = nasal
#' - `"O"` = oral
#' - `"P"` = parenteral
#' - `"R"` = rectal
#' - `"SL"` = sublingual/buccal
#' - `"TD"` = transdermal
#' - `"V"` = vaginal
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#'
#' Abbreviations of return values when using `property = "U"` (unit):
#'
#' - `"g"` = gram
#' - `"mg"` = milligram
#' - `"mcg"`` = microgram
#' - `"U"` = unit
#' - `"TU"` = thousand units
#' - `"MU"` = million units
#' - `"mmol"` = millimole
#' - `"ml"` = milliliter (e.g. eyedrops)
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#' @export
#' @rdname atc_online
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#' @inheritSection AMR Read more on our website!
#' @source <https://www.whocc.no/atc_ddd_alterations__cumulative/ddd_alterations/abbrevations/>
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#' @examples
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#' \dontrun{
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#' # oral DDD (Defined Daily Dose) of amoxicillin
#' atc_online_property("J01CA04", "DDD", "O")
#' # parenteral DDD (Defined Daily Dose) of amoxicillin
#' atc_online_property("J01CA04", "DDD", "P")
#'
#' atc_online_property("J01CA04", property = "groups") # search hierarchical groups of amoxicillin
#' # [1] "ANTIINFECTIVES FOR SYSTEMIC USE"
#' # [2] "ANTIBACTERIALS FOR SYSTEMIC USE"
#' # [3] "BETA-LACTAM ANTIBACTERIALS, PENICILLINS"
#' # [4] "Penicillins with extended spectrum"
#' }
atc_online_property <- function(atc_code,
property,
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administration = "O",
url = "https://www.whocc.no/atc_ddd_index/?code=%s&showdescription=no") {
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stopifnot_installed_package(c("curl", "rvest", "xml2"))
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has_internet <- get("has_internet", envir = asNamespace("curl"))
html_attr <- get("html_attr", envir = asNamespace("rvest"))
html_children <- get("html_children", envir = asNamespace("rvest"))
html_node <- get("html_node", envir = asNamespace("rvest"))
html_nodes <- get("html_nodes", envir = asNamespace("rvest"))
html_table <- get("html_table", envir = asNamespace("rvest"))
html_text <- get("html_text", envir = asNamespace("rvest"))
read_html <- get("read_html", envir = asNamespace("xml2"))
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check_dataset_integrity()
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if (!all(atc_code %in% antibiotics)) {
atc_code <- as.character(ab_atc(atc_code))
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}
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if (!has_internet()) {
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message("There appears to be no internet connection.")
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return(rep(NA, length(atc_code)))
}
if (length(property) != 1L) {
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stop("`property` must be of length 1", call. = FALSE)
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}
if (length(administration) != 1L) {
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stop("`administration` must be of length 1", call. = FALSE)
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}
# also allow unit as property
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if (property %like% "unit") {
property <- "U"
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}
# validation of properties
valid_properties <- c("ATC", "Name", "DDD", "U", "Adm.R", "Note", "groups")
valid_properties.bak <- valid_properties
property <- tolower(property)
valid_properties <- tolower(valid_properties)
if (!property %in% valid_properties) {
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stop("Invalid `property`, use one of ", paste(valid_properties.bak, collapse = ", "), ".")
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}
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if (property == "ddd") {
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returnvalue <- rep(NA_real_, length(atc_code))
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} else if (property == "groups") {
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returnvalue <- list()
} else {
returnvalue <- rep(NA_character_, length(atc_code))
}
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progress <- progress_estimated(n = length(atc_code), 3)
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on.exit(close(progress))
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for (i in seq_len(length(atc_code))) {
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progress$tick()
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atc_url <- sub("%s", atc_code[i], url, fixed = TRUE)
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if (property == "groups") {
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tbl <- read_html(atc_url) %>%
html_node("#content") %>%
html_children() %>%
html_node("a")
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# get URLS of items
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hrefs <- tbl %>% html_attr("href")
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# get text of items
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texts <- tbl %>% html_text()
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# select only text items where URL like "code="
texts <- texts[grepl("?code=", tolower(hrefs), fixed = TRUE)]
# last one is antibiotics, skip it
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texts <- texts[seq_len(length(texts)) - 1]
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returnvalue <- c(list(texts), returnvalue)
} else {
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tbl <- read_html(atc_url) %>%
html_nodes("table") %>%
html_table(header = TRUE) %>%
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as.data.frame(stringsAsFactors = FALSE)
# case insensitive column names
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colnames(tbl) <- gsub("^atc.*", "atc", tolower(colnames(tbl)))
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if (length(tbl) == 0) {
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warning("ATC not found: ", atc_code[i], ". Please check ", atc_url, ".", call. = FALSE)
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returnvalue[i] <- NA
next
}
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if (property %in% c("atc", "name")) {
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# ATC and name are only in first row
returnvalue[i] <- tbl[1, property]
} else {
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if (!"adm.r" %in% colnames(tbl) | is.na(tbl[1, "adm.r"])) {
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returnvalue[i] <- NA
next
} else {
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for (j in seq_len(nrow(tbl))) {
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if (tbl[j, "adm.r"] == administration) {
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returnvalue[i] <- tbl[j, property]
}
}
}
}
}
}
if (property == "groups" & length(returnvalue) == 1) {
returnvalue <- returnvalue[[1]]
}
returnvalue
}
#' @rdname atc_online
#' @export
atc_online_groups <- function(atc_code, ...) {
atc_online_property(atc_code = atc_code, property = "groups", ...)
}
#' @rdname atc_online
#' @export
atc_online_ddd <- function(atc_code, ...) {
atc_online_property(atc_code = atc_code, property = "ddd", ...)
}