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(v1.5.0.9011) small dosage update

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dr. M.S. (Matthijs) Berends
2021-01-24 23:27:11 +01:00
parent 286eaa9699
commit 24eb4453db
29 changed files with 207 additions and 110 deletions
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"AMP" "Ampicillin" "standard_dosage" "2 g" 3 "iv" "" "2 g x 3 iv" 11
"SAM" "Ampicillin/sulbactam" "high_dosage" "2 g + 1 g" 4 "iv" "" "(2 g ampicillin + 1 g sulbactam) x 4 iv" 11
"SAM" "Ampicillin/sulbactam" "standard_dosage" "2 g + 1 g" 3 "iv" "" "(2 g ampicillin + 1 g sulbactam) x 3 iv" 11
"AZM" "Azithromycin" "standard_dosage" "0.5 g" 1 "oral" "or 0.5 g x 1 iv" "0.5 g x 1 oral or 0.5 g x 1 iv" 11
"AZM" "Azithromycin" "standard_dosage" "0.5 g" 1 "iv" "" "0.5 g x 1 iv" 11
"AZM" "Azithromycin" "standard_dosage" "0.5 g" 1 "oral" "" "0.5 g x 1 oral" 11
"ATM" "Aztreonam" "high_dosage" "2 g" 4 "iv" "" "2 g x 4 iv" 11
"ATM" "Aztreonam" "standard_dosage" "1 g" 3 "iv" "" "1 g x 3 iv" 11
"PEN" "Benzylpenicillin" "high_dosage" "1.2 g" 4 "iv" "" "1.2 g (2 MU) x 4-6 iv" 11
"PEN" "Benzylpenicillin" "standard_dosage" "0.6 g" 4 "iv" "" "0.6 g (1 MU) x 4 iv" 11
"CEC" "Cefaclor" "high_dosage" "1 g" 3 "oral" "" "1 g x 3 oral" 11
"CEC" "Cefaclor" "standard_dosage" "0.25-0.5 g" 3 "oral" "depending on species and/or infection type" "0.25-0.5 g x 3 oral depending on species and/or infection type" 11
"CEC" "Cefaclor" "standard_dosage" "0.25-0.5 g" 3 "oral" "" "0.25-0.5 g x 3 oral" 11
"CFR" "Cefadroxil" "standard_dosage" "0.5-1 g" 2 "oral" "" "0.5-1 g x 2 oral" 11
"CFR" "Cefadroxil" "uncomplicated_uti" "0.5-1 g" 2 "oral" "" "0.5-1 g x 2 oral" 11
"CZO" "Cefazolin" "high_dosage" "2 g" 3 "iv" "" "2 g x 3 iv" 11
"CZO" "Cefazolin" "standard_dosage" "1 g" 3 "iv" "" "1 g x 3 iv" 11
"FEP" "Cefepime" "high_dosage" "2 g" 3 "iv" "" "2 g x 3 iv" 11
"FEP" "Cefepime" "standard_dosage" "1 g" 3 "iv" "or 2 g x 2 iv" "1 g x 3 iv or 2 g x 2 iv" 11
"FEP" "Cefepime" "standard_dosage" "2 g" 2 "iv" "" "2 g x 2 iv" 11
"FDC" "Cefiderocol" "standard_dosage" "2 g" 3 "iv" "over 3 hours" "2 g x 3 iv over 3 hours" 11
"CFM" "Cefixime" "standard_dosage" "0.2-0.4 g" 2 "oral" "" "0.2-0.4 g x 2 oral" 11
"CFM" "Cefixime" "uncomplicated_uti" "0.2-0.4 g" 2 "oral" "" "0.2-0.4 g x 2 oral" 11
@ -36,14 +37,14 @@
"CPD" "Cefpodoxime" "uncomplicated_uti" "0.1-0.2 g" 2 "oral" "" "0.1-0.2 g x 2 oral" 11
"CPT" "Ceftaroline" "high_dosage" "0.6 g" 3 "iv" "over 2 hours" "0.6 g x 3 iv over 2 hours" 11
"CPT" "Ceftaroline" "standard_dosage" "0.6 g" 2 "iv" "over 1 hour" "0.6 g x 2 iv over 1 hour" 11
"CAZ" "Ceftazidime" "high_dosage" "2 g" 3 "iv" "or 1 g x 6 iv" "2 g x 3 iv or 1 g x 6 iv" 11
"CAZ" "Ceftazidime" "high_dosage" "1 g" 6 "iv" "" "1 g x 6 iv" 11
"CAZ" "Ceftazidime" "standard_dosage" "1 g" 3 "iv" "" "1 g x 3 iv" 11
"CZA" "Ceftazidime/avibactam" "standard_dosage" "2 g + 0.5 g" 3 "iv" "over 2 hours" "(2 g ceftazidime + 0.5 g avibactam) x 3 iv over 2 hours" 11
"CTB" "Ceftibuten" "standard_dosage" "0.4 g" 1 "oral" "" "0.4 g x 1 oral" 11
"BPR" "Ceftobiprole" "standard_dosage" "0.5 g" 3 "iv" "over 2 hours" "0.5 g x 3 iv over 2 hours" 11
"CZT" "Ceftolozane/tazobactam" "standard_dosage" "1 g + 0.5 g" 3 "iv" "over 1 hour" "(1 g ceftolozane + 0.5 g tazobactam) x 3 iv over 1 hour" 11
"CZT" "Ceftolozane/tazobactam" "standard_dosage" "2 g + 1 g" 3 "iv" "over 1 hour" "(2 g ceftolozane + 1 g tazobactam) x 3 iv over 1 hour" 11
"CRO" "Ceftriaxone" "high_dosage" "2 g" 2 "iv" "or 4 g x 1 iv" "2 g x 2 iv or 4 g x 1 iv" 11
"CRO" "Ceftriaxone" "high_dosage" "4 g" 1 "iv" "" "4 g x 1 iv" 11
"CRO" "Ceftriaxone" "standard_dosage" "2 g" 1 "iv" "" "2 g x 1 iv" 11
"CXM" "Cefuroxime" "high_dosage" "1.5 g" 3 "iv" "" "1.5 g x 3 iv" 11
"CXM" "Cefuroxime" "standard_dosage" "0.75 g" 3 "iv" "" "0.75 g x 3 iv" 11
@ -52,70 +53,100 @@
"CXM" "Cefuroxime" "uncomplicated_uti" "0.25 g" 2 "oral" "" "0.25 g x 2 oral" 11
"LEX" "Cephalexin" "standard_dosage" "0.25-1 g" 2 "oral" "" "0.25-1 g x 2-3 oral" 11
"LEX" "Cephalexin" "uncomplicated_uti" "0.25-1 g" 2 "oral" "" "0.25-1 g x 2-3 oral" 11
"CHL" "Chloramphenicol" "high_dosage" "2 g" 4 "oral" "or 2 g x 4 iv" "2 g x 4 oral or 2 g x 4 iv" 11
"CHL" "Chloramphenicol" "standard_dosage" "1 g" 4 "oral" "or 1 g x 4 iv" "1 g x 4 oral or 1 g x 4 iv" 11
"CIP" "Ciprofloxacin" "high_dosage" "0.75 g" 2 "oral" "or 0.4 g x 3 iv" "0.75 g x 2 oral or 0.4 g x 3 iv" 11
"CIP" "Ciprofloxacin" "standard_dosage" "0.5 g" 2 "oral" "or 0.4 g x 2 iv" "0.5 g x 2 oral or 0.4 g x 2 iv" 11
"CHL" "Chloramphenicol" "high_dosage" "2 g" 4 "iv" "" "2 g x 4 iv" 11
"CHL" "Chloramphenicol" "standard_dosage" "1 g" 4 "iv" "" "1 g x 4 iv" 11
"CHL" "Chloramphenicol" "high_dosage" "2 g" 4 "oral" "" "2 g x 4 oral" 11
"CHL" "Chloramphenicol" "standard_dosage" "1 g" 4 "oral" "" "1 g x 4 oral" 11
"CIP" "Ciprofloxacin" "high_dosage" "0.4 g" 3 "iv" "" "0.4 g x 3 iv" 11
"CIP" "Ciprofloxacin" "standard_dosage" "0.4 g" 2 "iv" "" "0.4 g x 2 iv" 11
"CIP" "Ciprofloxacin" "high_dosage" "0.75 g" 2 "oral" "" "0.75 g x 2 oral" 11
"CIP" "Ciprofloxacin" "standard_dosage" "0.5 g" 2 "oral" "" "0.5 g x 2 oral" 11
"CLR" "Clarithromycin" "high_dosage" "0.5 g" 2 "oral" "" "0.5 g x 2 oral" 11
"CLR" "Clarithromycin" "standard_dosage" "0.25 g" 2 "oral" "" "0.25 g x 2 oral" 11
"CLI" "Clindamycin" "high_dosage" "0.3 g" 4 "oral" "or 0.9 g x 3 iv" "0.3 g x 4 oral or 0.9 g x 3 iv" 11
"CLI" "Clindamycin" "standard_dosage" "0.3 g" 2 "oral" "or 0.6 g x 3 iv" "0.3 g x 2 oral or 0.6 g x 3 iv" 11
"CLO" "Cloxacillin" "high_dosage" "1 g" 4 "oral" "or 2 g x 6 iv" "1 g x 4 oral or 2 g x 6 iv" 11
"CLO" "Cloxacillin" "standard_dosage" "0.5 g" 4 "oral" "or 1 g x 4 iv" "0.5 g x 4 oral or 1 g x 4 iv" 11
"CLI" "Clindamycin" "high_dosage" "0.9 g" 3 "iv" "" "0.9 g x 3 iv" 11
"CLI" "Clindamycin" "standard_dosage" "0.6 g" 3 "iv" "" "0.6 g x 3 iv" 11
"CLI" "Clindamycin" "high_dosage" "0.3 g" 4 "oral" "" "0.3 g x 4 oral" 11
"CLI" "Clindamycin" "standard_dosage" "0.3 g" 2 "oral" "" "0.3 g x 2 oral" 11
"CLO" "Cloxacillin" "high_dosage" "2 g" 6 "iv" "" "2 g x 6 iv" 11
"CLO" "Cloxacillin" "standard_dosage" "1 g" 4 "iv" "" "1 g x 4 iv" 11
"CLO" "Cloxacillin" "high_dosage" "1 g" 4 "oral" "" "1 g x 4 oral" 11
"CLO" "Cloxacillin" "standard_dosage" "0.5 g" 4 "oral" "" "0.5 g x 4 oral" 11
"COL" "Colistin" "standard_dosage" "4.5 MU" 2 "iv" "loading dose of 9 MU" "4.5 MU x 2 iv with a loading dose of 9 MU" 11
"DAL" "Dalbavancin" "standard_dosage" "1 g" 1 "iv" "over 30 minutes on day 8" "1 g x 1 iv over 30 minutes on day 1 If needed, 0.5 g x 1 iv over 30 minutes on day 8" 11
"DAP" "Daptomycin" "standard_dosage" "4 mg/kg" 1 "iv" "" "4 mg/kg x 1 iv" 11
"DAP" "Daptomycin" "standard_dosage" "6 mg/kg" 1 "iv" "" "6 mg/kg x 1 iv" 11
"DFX" "Delafloxacin" "standard_dosage" "0.45 g" 2 "oral" "or 0.3 g x 2 iv" "0.45 g x 2 oral or 0.3 g x 2 iv" 11
"DIC" "Dicloxacillin" "high_dosage" "2 g" 4 "oral" "or 2 g x 6 iv" "2 g x 4 oral or 2 g x 6 iv" 11
"DIC" "Dicloxacillin" "standard_dosage" "0.5-1 g" 4 "oral" "or 1 g x 4 iv" "0.5-1 g x 4 oral or 1 g x 4 iv" 11
"DFX" "Delafloxacin" "standard_dosage" "0.3 g" 2 "iv" "" "0.3 g x 2 iv" 11
"DFX" "Delafloxacin" "standard_dosage" "0.45 g" 2 "oral" "" "0.45 g x 2 oral" 11
"DIC" "Dicloxacillin" "high_dosage" "2 g" 6 "iv" "" "2 g x 6 iv" 11
"DIC" "Dicloxacillin" "standard_dosage" "1 g" 4 "iv" "" "1 g x 4 iv" 11
"DIC" "Dicloxacillin" "high_dosage" "2 g" 4 "oral" "" "2 g x 4 oral" 11
"DIC" "Dicloxacillin" "standard_dosage" "0.5-1 g" 4 "oral" "" "0.5-1 g x 4 oral" 11
"DOR" "Doripenem" "high_dosage" "1 g" 3 "iv" "over 1 hour" "1 g x 3 iv over 1 hour" 11
"DOR" "Doripenem" "standard_dosage" "0.5 g" 3 "iv" "over 1 hour" "0.5 g x 3 iv over 1 hour" 11
"DOX" "Doxycycline" "high_dosage" "0.2 g" 1 "oral" "" "0.2 g x 1 oral" 11
"DOX" "Doxycycline" "standard_dosage" "0.1 g" 1 "oral" "" "0.1 g x 1 oral" 11
"ERV" "Eravacycline" "standard_dosage" "1 mg/kg" 2 "iv" "" "1 mg/kg x 2 iv" 11
"ETP" "Ertapenem" "standard_dosage" "1 g" 1 "iv" "over 30 minutes" "1 g x 1 iv over 30 minutes" 11
"ERY" "Erythromycin" "high_dosage" "1 g" 4 "oral" "or 1 g x 4 iv" "1 g x 4 oral or 1 g x 4 iv" 11
"ERY" "Erythromycin" "standard_dosage" "0.5 g" 2 "oral" "or 0.5 g x 2-4 iv" "0.5 g x 2-4 oral or 0.5 g x 2-4 iv" 11
"ERY" "Erythromycin" "high_dosage" "1 g" 4 "iv" "" "1 g x 4 iv" 11
"ERY" "Erythromycin" "standard_dosage" "0.5 g" 2 "iv" "" "0.5 g x 2-4 iv" 11
"ERY" "Erythromycin" "high_dosage" "1 g" 4 "oral" "" "1 g x 4 oral" 11
"ERY" "Erythromycin" "standard_dosage" "0.5 g" 2 "oral" "" "0.5 g x 2-4 oral" 11
"FDX" "Fidaxomicin" "standard_dosage" "0.2 g" 2 "oral" "" "0.2 g x 2 oral" 11
"FLC" "Flucloxacillin" "high_dosage" "1 g" 4 "oral" "or 2 g x 6 iv" "1 g x 4 oral or 2 g x 6 iv" 11
"FLC" "Flucloxacillin" "standard_dosage" "1 g" 3 "oral" "or 2 g x 4 iv (or 1 g x 6 iv)" "1 g x 3 oral or 2 g x 4 iv (or 1 g x 6 iv)" 11
"FLC" "Flucloxacillin" "high_dosage" "2 g" 6 "iv" "" "2 g x 6 iv" 11
"FLC" "Flucloxacillin" "standard_dosage" "2 g" 4 "iv" "" "2 g x 4 iv (or 1 g x 6 iv)" 11
"FLC" "Flucloxacillin" "high_dosage" "1 g" 4 "oral" "" "1 g x 4 oral" 11
"FLC" "Flucloxacillin" "standard_dosage" "1 g" 3 "oral" "" "1 g x 3 oral" 11
"FOS" "Fosfomycin" "high_dosage" "8 g" 3 "iv" "" "8 g x 3 iv" 11
"FOS" "Fosfomycin" "standard_dosage" "4 g" 3 "iv" "" "4 g x 3 iv" 11
"FUS" "Fusidic acid" "high_dosage" "0.5 g" 3 "oral" "or 0.5 g x 3 iv" "0.5 g x 3 oral or 0.5 g x 3 iv" 11
"FUS" "Fusidic acid" "standard_dosage" "0.5 g" 2 "oral" "or 0.5 g x 2 iv" "0.5 g x 2 oral or 0.5 g x 2 iv" 11
"FUS" "Fusidic acid" "high_dosage" "0.5 g" 3 "iv" "" "0.5 g x 3 iv" 11
"FUS" "Fusidic acid" "standard_dosage" "0.5 g" 2 "iv" "" "0.5 g x 2 iv" 11
"FUS" "Fusidic acid" "high_dosage" "0.5 g" 3 "oral" "" "0.5 g x 3 oral" 11
"FUS" "Fusidic acid" "standard_dosage" "0.5 g" 2 "oral" "" "0.5 g x 2 oral" 11
"GEN" "Gentamicin" "standard_dosage" "6-7 mg/kg" 1 "iv" "" "6-7 mg/kg x 1 iv" 11
"IPM" "Imipenem" "high_dosage" "1 g" 4 "iv" "over 30 minutes" "1 g x 4 iv over 30 minutes" 11
"IPM" "Imipenem" "standard_dosage" "0.5 g" 4 "iv" "over 30 minutes" "0.5 g x 4 iv over 30 minutes" 11
"IMR" "Imipenem/relebactam" "standard_dosage" "0.5 g + 0.25 g" 4 "iv" "over 30 minutes" "(0.5 g imipenem + 0.25 g relebactam) x 4 iv over 30 minutes" 11
"IMR" "Imipenem/relebactam" "standard_dosage" "0.5 g + 0.25 g" 4 "iv" "over 30 minutes" "(0.5 g imipenem + 0.25 g relebactam) x 4 iv over 30 minutes" 11
"LMU" "Lefamulin" "standard_dosage" "0.15 g" 2 "iv" "or 0.6 g x 2 oral" "0.15 g x 2 iv or 0.6 g x 2 oral" 11
"LVX" "Levofloxacin" "high_dosage" "0.5 g" 2 "oral" "or 0.5 g x 2 iv" "0.5 g x 2 oral or 0.5 g x 2 iv" 11
"LVX" "Levofloxacin" "standard_dosage" "0.5 g" 1 "oral" "or 0.5 g x 1 iv" "0.5 g x 1 oral or 0.5 g x 1 iv" 11
"LNZ" "Linezolid" "standard_dosage" "0.6 g" 2 "oral" "or 0.6 g x 2 iv" "0.6 g x 2 oral or 0.6 g x 2 iv" 11
"LMU" "Lefamulin" "standard_dosage" "0.6 g" 2 "oral" "" "0.6 g x 2 oral" 11
"LVX" "Levofloxacin" "high_dosage" "0.5 g" 2 "iv" "" "0.5 g x 2 iv" 11
"LVX" "Levofloxacin" "standard_dosage" "0.5 g" 1 "iv" "" "0.5 g x 1 iv" 11
"LVX" "Levofloxacin" "high_dosage" "0.5 g" 2 "oral" "" "0.5 g x 2 oral" 11
"LVX" "Levofloxacin" "standard_dosage" "0.5 g" 1 "oral" "" "0.5 g x 1 oral" 11
"LNZ" "Linezolid" "standard_dosage" "0.6 g" 2 "iv" "" "0.6 g x 2 iv" 11
"LNZ" "Linezolid" "standard_dosage" "0.6 g" 2 "oral" "" "0.6 g x 2 oral" 11
"MEM" "Meropenem" "high_dosage" "2 g" 3 "iv" "over 3 hours" "2 g x 3 iv over 3 hours" 11
"MEM" "Meropenem" "standard_dosage" "1 g" 3 "iv" "over 30 minutes" "1 g x 3 iv over 30 minutes" 11
"MEV" "Meropenem/vaborbactam" "standard_dosage" "2 g + 2 g" 3 "iv" "over 3 hours" "(2 g meropenem + 2 g vaborbactam) x 3 iv over 3 hours" 11
"MTR" "Metronidazole" "high_dosage" "0.5 g" 3 "oral" "or 0.5 g x 3 iv" "0.5 g x 3 oral or 0.5 g x 3 iv" 11
"MTR" "Metronidazole" "standard_dosage" "0.4 g" 3 "oral" "or 0.4 g x 3 iv" "0.4 g x 3 oral or 0.4 g x 3 iv" 11
"MTR" "Metronidazole" "high_dosage" "0.5 g" 3 "iv" "" "0.5 g x 3 iv" 11
"MTR" "Metronidazole" "standard_dosage" "0.4 g" 3 "iv" "" "0.4 g x 3 iv" 11
"MTR" "Metronidazole" "high_dosage" "0.5 g" 3 "oral" "" "0.5 g x 3 oral" 11
"MTR" "Metronidazole" "standard_dosage" "0.4 g" 3 "oral" "" "0.4 g x 3 oral" 11
"MNO" "Minocycline" "standard_dosage" "0.1 g" 2 "oral" "" "0.1 g x 2 oral" 11
"MFX" "Moxifloxacin" "standard_dosage" "0.4 g" 1 "oral" "or 0.4 g x 1 iv" "0.4 g x 1 oral or 0.4 g x 1 iv" 11
"OFX" "Ofloxacin" "high_dosage" "0.4 g" 2 "oral" "or 0.4 g x 2 iv" "0.4 g x 2 oral or 0.4 g x 2 iv" 11
"OFX" "Ofloxacin" "standard_dosage" "0.2 g" 2 "oral" "or 0.2 g x 2 iv" "0.2 g x 2 oral or 0.2 g x 2 iv" 11
"MFX" "Moxifloxacin" "standard_dosage" "0.4 g" 1 "iv" "" "0.4 g x 1 iv" 11
"MFX" "Moxifloxacin" "standard_dosage" "0.4 g" 1 "oral" "" "0.4 g x 1 oral" 11
"OFX" "Ofloxacin" "high_dosage" "0.4 g" 2 "iv" "" "0.4 g x 2 iv" 11
"OFX" "Ofloxacin" "standard_dosage" "0.2 g" 2 "iv" "" "0.2 g x 2 iv" 11
"OFX" "Ofloxacin" "high_dosage" "0.4 g" 2 "oral" "" "0.4 g x 2 oral" 11
"OFX" "Ofloxacin" "standard_dosage" "0.2 g" 2 "oral" "" "0.2 g x 2 oral" 11
"ORI" "Oritavancin" "standard_dosage" "1.2 g" 1 "iv" "" "1.2 g x 1 (single dose) iv over 3 hours" 11
"OXA" "Oxacillin" "high_dosage" "1 g" 6 "iv" "" "1 g x 6 iv" 11
"OXA" "Oxacillin" "standard_dosage" "1 g" 4 "iv" "" "1 g x 4 iv" 11
"PHN" "Phenoxymethylpenicillin" "standard_dosage" "0.5-2 g" 3 "oral" "depending on species and/or infection type" "0.5-2 g x 3-4 oral depending on species and/or infection type" 11
"PHN" "Phenoxymethylpenicillin" "standard_dosage" "0.5-2 g" 3 "oral" "" "0.5-2 g x 3-4 oral" 11
"PIP" "Piperacillin" "high_dosage" "4 g" 4 "iv" "" "4 g x 4 iv by extended 3-hour infusion" 11
"PIP" "Piperacillin" "standard_dosage" "4 g" 4 "iv" "" "4 g x 4 iv" 11
"TZP" "Piperacillin/tazobactam" "high_dosage" "4 g + 0.5 g" 4 "iv" "" "(4 g piperacillin + 0.5 g tazobactam) x 4 iv by extended 3-hour infusion" 11
"TZP" "Piperacillin/tazobactam" "standard_dosage" "4 g + 0.5 g" 4 "iv" "" "(4 g piperacillin + 0.5 g tazobactam) x 4 iv or x 3 by extended 4-hour infusion" 11
"QDA" "Quinupristin/dalfopristin" "high_dosage" "7.5 mg/kg" 3 "iv" "" "7.5 mg/kg x 3 iv" 11
"QDA" "Quinupristin/dalfopristin" "standard_dosage" "7.5 mg/kg" 2 "iv" "" "7.5 mg/kg x 2 iv" 11
"RIF" "Rifampicin" "high_dosage" "0.6 g" 2 "oral" "or 0.6 g x 2 iv" "0.6 g x 2 oral or 0.6 g x 2 iv" 11
"RIF" "Rifampicin" "standard_dosage" "0.6 g" 1 "oral" "or 0.6 g x 1 iv" "0.6 g x 1 oral or 0.6 g x 1 iv" 11
"RIF" "Rifampicin" "high_dosage" "0.6 g" 2 "iv" "" "0.6 g x 2 iv" 11
"RIF" "Rifampicin" "standard_dosage" "0.6 g" 1 "iv" "" "0.6 g x 1 iv" 11
"RIF" "Rifampicin" "high_dosage" "0.6 g" 2 "oral" "" "0.6 g x 2 oral" 11
"RIF" "Rifampicin" "standard_dosage" "0.6 g" 1 "oral" "" "0.6 g x 1 oral" 11
"RXT" "Roxithromycin" "standard_dosage" "0.15 g" 2 "oral" "" "0.15 g x 2 oral" 11
"SPT" "Spectinomycin" "standard_dosage" "2 g" 1 "im" "" "2 g x 1 im" 11
"TZD" "Tedizolid" "standard_dosage" "0.2 g" 1 "oral" "or 0.2 g x 1 iv" "0.2 g x 1 oral or 0.2 g x 1 iv" 11
"TZD" "Tedizolid" "standard_dosage" "0.2 g" 1 "iv" "" "0.2 g x 1 iv" 11
"TZD" "Tedizolid" "standard_dosage" "0.2 g" 1 "oral" "" "0.2 g x 1 oral" 11
"TEC" "Teicoplanin" "high_dosage" "0.8 g" 1 "iv" "" "0.8 g x 1 iv" 11
"TEC" "Teicoplanin" "standard_dosage" "0.4 g" 1 "iv" "" "0.4 g x 1 iv" 11
"TLV" "Telavancin" "standard_dosage" "10 mg/kg" 1 "iv" "over 1 hour" "10 mg/kg x 1 iv over 1 hour" 11
@ -130,7 +161,10 @@
"TCC" "Ticarcillin/clavulanic acid" "standard_dosage" "3 g + 0.1-0.2 g" 4 "iv" "" "(3 g ticarcillin + 0.1-0.2 g clavulanic acid) x 4 iv" 11
"TGC" "Tigecycline" "standard_dosage" "0.1 g" "loading dose followed by 50 mg x 2 iv" "0.1 g loading dose followed by 50 mg x 2 iv" 11
"TOB" "Tobramycin" "standard_dosage" "6-7 mg/kg" 1 "iv" "" "6-7 mg/kg x 1 iv" 11
"SXT" "Trimethoprim/sulfamethoxazole" "high_dosage" "0.24 g + 1.2 g" 2 "oral" "" "(0.24 g trimethoprim + 1.2 g sulfamethoxazole) x 2 oral" 11
"SXT" "Trimethoprim/sulfamethoxazole" "high_dosage" "0.24 g + 1.2 g" 2 "oral" "" "(0.24 g trimethoprim + 1.2 g sulfamethoxazole) x 2 oral or (0.24 g trimethoprim + 1.2 g sulfamethoxazole) x 2 iv" 11
"SXT" "Trimethoprim/sulfamethoxazole" "standard_dosage" "0.16 g + 0.8 g" 2 "oral" "" "(0.16 g trimethoprim + 0.8 g sulfamethoxazole) x 2 oral" 11
"SXT" "Trimethoprim/sulfamethoxazole" "standard_dosage" "0.16 g + 0.8 g" 2 "oral" "" "(0.16 g trimethoprim + 0.8 g sulfamethoxazole) x 2 oral or (0.16 g trimethoprim + 0.8 g sulfamethoxazole) x 2 iv" 11
"SXT" "Trimethoprim/sulfamethoxazole" "uncomplicated_uti" "0.16 g + 0.8 g" 2 "oral" "" "(0.16 g trimethoprim + 0.8 g sulfamethoxazole) x 2 oral" 11
"VAN" "Vancomycin" "standard_dosage" "0.5 g" 4 "iv" "or 1 g x 2 iv or 2 g x 1 by continuous infusion" "0.5 g x 4 iv or 1 g x 2 iv or 2 g x 1 by continuous infusion" 11
"SXT" "Trimethoprim/sulfamethoxazole" "uncomplicated_uti" "0.16 g + 0.8 g" 2 "oral" "" "(0.16 g trimethoprim + 0.8 g sulfamethoxazole) x 2 oral" 11
"VAN" "Vancomycin" "standard_dosage" "1 g" 2 "iv" "" "1 g x 2 iv or 2 g x 1 by continuous infusion" 11

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data-raw/dosage.xlsx
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data-raw/reproduction_of_dosage.R
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@ -44,6 +44,28 @@ dosage_source <- read_excel("data-raw/Dosages_v_11.0_Breakpoint_Tables.xlsx", sk
mutate(ab = as.ab(drug),
ab_name = ab_name(ab, language = NULL))
dosage_source <- bind_rows(
# oral
dosage_source %>%
filter(standard_dosage %like% " oral") %>%
mutate(standard_dosage = gsub("oral.*", "oral", standard_dosage),
high_dosage = if_else(high_dosage %like% "oral",
gsub("oral.*", "oral", high_dosage),
NA_character_)),
# iv
dosage_source %>%
filter(standard_dosage %like% " iv") %>%
mutate(standard_dosage = gsub(".* or ", "", standard_dosage),
high_dosage = if_else(high_dosage %like% "( or | iv)",
gsub(".* or ", "", high_dosage),
NA_character_)),
# im
dosage_source %>%
filter(standard_dosage %like% " im")
) %>%
arrange(drug)
get_dosage_lst <- function(col_data) {
standard <- col_data %>%
# remove new lines
@ -90,6 +112,7 @@ standard <- get_dosage_lst(dosage_source$standard_dosage)
high <- get_dosage_lst(dosage_source$high_dosage)
uti <- get_dosage_lst(dosage_source$uncomplicated_uti)
dosage <- bind_rows(
# standard dose
data.frame(
ab = dosage_source$ab,
name = dosage_source$ab_name,
@ -101,6 +124,7 @@ dosage <- bind_rows(
original_txt = sapply(standard, function(x) x$original_txt),
stringsAsFactors = FALSE
),
# high dose
data.frame(
ab = dosage_source$ab,
name = dosage_source$ab_name,
@ -112,6 +136,7 @@ dosage <- bind_rows(
original_txt = sapply(high, function(x) x$original_txt),
stringsAsFactors = FALSE
),
# UTIs
data.frame(
ab = dosage_source$ab,
name = dosage_source$ab_name,
@ -124,8 +149,11 @@ dosage <- bind_rows(
stringsAsFactors = FALSE
)) %>%
mutate(eucast_version = breakpoints_version,
dose_times = as.integer(dose_times)) %>%
dose_times = as.integer(dose_times),
administration = gsub("([a-z]+) .*", "\\1", administration)) %>%
arrange(name, administration, type) %>%
filter(!is.na(dose), dose != ".")
filter(!is.na(dose), dose != ".") %>%
as.data.frame(stringsAsFactors = FALSE)
rownames(dosage) <- NULL
usethis::use_data(dosage, internal = FALSE, overwrite = TRUE, version = 2)