Commit Graph
29 Commits
Author SHA1 Message Date
dr. M.S. (Matthijs) Berends eb9a9c2fa5 (v3.0.1.9149) Fix WHONET codes in microorganisms.codes that referred to unrelated microorganisms, let codes refer to the name they were named after and add a source column, and replace the fuzzy matching of WHONET names by exact matching with a guard against unreviewed remaps
WHONET names are now matched exactly (also outdated names, after removing qualifiers), then on GBIF identifier, and fuzzy results are only kept if consistent with that; otherwise the genus or UNKNOWN is used. A code refers to the record of the name it was named after (e.g. EAE is Enterobacter aerogenes) if that name refers to the same taxon. Every remap of an existing code to another taxon must be listed in data-raw/whonet_remaps_reviewed.csv; the 198 remaps of this rebuild were reviewed.
2026-10-15 21:08:04 +02:00
dr. M.S. (Matthijs) Berends 179eec584f (v3.0.1.9148) Store zone diameters without S category as blocking rows for EUCAST and as R-only rows for CLSI instead of capping them at 50 mm, let as.mo() return the complex for names such as 'Acinetobacter calcoaceticus-baumannii complex', make the breakpoint reproduction scripts stop on unchecked data defects and year-independent, and document that as.disk() returns NA above 50 mm
The full rebuild of clinical_breakpoints also assigns Salmonella serovars and the Bacteroides fragilis complex correctly and adds ECOFFs for Neocosmospora solani. The rebuilt microorganisms.codes is not included, since it remaps WHONET codes that need review first.
2026-10-15 17:05:41 +02:00
dr. M.S. (Matthijs) Berends fcfaa87f5d (v3.0.1.9147) Keep EUCAST blocking rows for infections other than UTI where EUCAST only gives a UTI breakpoint, e.g. breakpoints in brackets for aminoglycosides in Acinetobacter, and let as.sir() with unknown uti consistently prefer non-UTI breakpoints, use UTI breakpoints only if no others exist and note this in sir_interpretation_history() every time
The pruning of blocking rows in the EUCAST reproduction script now compares UTI status too, and the script is fixed for the renamed column of the as.ab() coercion cache. In clinical_breakpoints, only the blocking rows were replaced (356 organism/agent/method combinations newly blocked, none unblocked); other changes of a full rebuild, caused by taxonomy updates in the WHONET-based rows, are not included.
2026-10-15 14:55:57 +02:00
dr. M.S. (Matthijs) Berends 16a13ba81f (v3.0.1.9109) Fix WHONET codes SUD and ROX in clinical_breakpoints, and add sulbactam/durlobactam (#308) 2026-10-10 09:42:25 +02:00
dr. M.S. (Matthijs) Berends 9e05fe184b (v3.0.1.9106) Fix trade names of combinations filed under a single agent, and remove non-synonyms from antimicrobials (#315) 2026-10-09 22:25:44 +02:00
Matthijs BerendsandClaude Opus 5.5 0ca43df459 Update taxonomy of microorganisms (2026-10) (#312)
* Update taxonomy of microorganisms (2026-10)

Rebuild of the microorganisms data set from COL 2026-04-18 XR, LPSN and BacDive of October 2026
and MycoBank of January 2026, with v3.0.1 as the previous data set: 111,103 records (v3.0.1:
78,679), 0 changed MO codes of existing names, 522 released codes retired (275 to be reviewed).

Script fixes (data-raw/_reproduction_scripts/reproduction_of_microorganisms.R):
- previous data set from the last release; COL read as COL Data Package (NameUsage.tsv)
- keep COL records without authors (a filter on NA dropped them, e.g. Balamuthia mandrillaris)
- genus homonyms: unclassified MycoBank entries are not authoritative; the released domain of a
  genus wins if a source supports it (e.g. Moorella, Serpula, Pirella stay Bacteria)
- protect current names of relevant species instead of whole current genera (data set tripled)
- current names and synonyms only within the same domain and for known names (Brugia -> Lycoperdon)
- MycoBank names in Latin script only; old records outside their source's scope become manually added
- Graphium butterflies of v3.0.1 are not carried over, re-added or restored
- restore released taxa by name and rank; retire older cross-domain homonyms for review
- fill empty families from COL and a commented override list (Ascaris, Balamuthia)
- add Brugia malayi and B. timori; remove Salmonella species synonyms that are serovars
- BacDive: a minority of facultative strain records no longer decides (C. difficile)
- translate codes of other data sets with the development version; review unmatched codes
- scope decisions: COL XR names only if relevant or released; Protozoa follow the Fungi rules

Also: all checkpoints (data-raw/taxonomy*.rds), updated data sets, Bartlett et al. list, accessed
dates in TAXONOMY_VERSION, NEWS, two staphylococci added to CoNS, tests updated for real taxonomic
changes, known defects file removed (all solved), and the findings report with all review files in
data-raw/taxonomy_review/2026-10/.

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy review report: note on the .dta export and the single commit

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Fix as.mo() for Salmonella serovars written with the species; add S. xeri to CoNS

- "Salmonella enterica (subsp. enterica) serovar Typhi" returned S. bongori, and
  "S. enterica Typhimurium" S. enterica diarizonae; "Paratyphi A/B/C" became serogroups
- Staphylococcus xeri and S. parequorum confirmed as coagulase-negative

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy build: remove lichens (decision of 5 October 2026)

Fungi in the lichen-forming classes and the order Verrucariales are removed unless their genus is
clinically relevant, with the synonyms that point to them (4,155 records); released lichens are
restored. microorganisms now has 107,126 records (Fungi 45,739); all tests pass.

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy review decisions: microsporidia in Fungi, accepted names, missing protozoa

- all microsporidia in the Fungi (1,394 names of v3.0.1 from P_ to F_, old codes translated by name)
- Enterocytozoon bieneusi and Encephalitozoon cuniculi as accepted names (accepted_name_override)
- Balantidium and Isospora added to MO_RELEVANT_GENERA; Cystoisospora belli as synonym of Isospora belli
- synonym cycles decided: Capillidium and Scolecobasidium are the current genera
- removed the stale data-raw/taxonomy_lpsn0.rds
- microorganisms now has 107,253 records; all tests pass

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy review report: all items reviewed

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Rule matching by accepted taxon; Erysipelatoclostridium as synonym of Thomasclavelia

- interpretive_rules(): species named in a rule (literal names, genus_species/fullname) now also match all other
  names of the same accepted taxon, e.g. 'Clostridium ramosum' for Thomasclavelia ramosa; not for genera or regex rules
- Erysipelatoclostridium and its species are synonyms of Thomasclavelia (accepted_name_override); E. merdavium is
  retired by decision of 6 October 2026, and the build removes taxa retired by a human decision
- microorganisms patched with the same logic as the build script (no full rebuild): 107,252 records
- intrinsic_resistant regenerated with the new taxonomy and rule matching: 308,646 rows
- clinical_breakpoints: EUCAST workbook rows merged again, 24 EUCAST 2026 rows moved from C. ramosum to T. ramosa

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy: correct records for names listed twice, no synonyms without a current name, strict data tests

- one record per name keeps the accepted record (e.g. Eggerthella lenta, Gordonia amarae, Anisakis simplex and
  Enterobius vermicularis were synonyms without a current name), links to dropped records are moved
- LPSN lookup reads the taxonomic status and correct name; validly published synonyms are no longer 'accepted'
- synonyms without a current name: linked via LPSN or removed, released codes retired (3,668); records with kept
  children become 'unknown'; the M. tuberculosis complex is protected (decisions of 7 October 2026)
- subspecies codes reserved, current names of synonyms kept when pruning, missing parent records added or moved,
  higher taxonomy harmonised, shared identifiers resolved per domain and rank, pointers and parent links cleaned
- data sets refer only to current names (except intrinsic_resistant); group members only from current names;
  internal CoNS/CoPS/streptococcal lists keep a synonym only with its current name
- intrinsic_resistant, clinical_breakpoints (EUCAST workbooks) and microorganisms.groups regenerated
- 28 new tests in test-data.R; devtools::test(): 1,581 expectations, 0 failures
- open decisions listed in data-raw/taxonomy_review/2026-10/REPORT.md, section 6

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy: protect WHO priority genera, follow LPSN for the M. tuberculosis complex, place protist groups in one domain

- all taxa of the genera in MO_WHO_PRIORITY_GENERA are protected, also names that are not validly published
  (replaces the hard-coded M. tuberculosis complex; keeps e.g. Klebsiella quasivariicola, M. canettii, M. orygis)
- LPSN is followed for the M. tuberculosis complex: M. bovis, M. africanum, M. caprae, M. microti and M. pinnipedii
  are heterotypic synonyms of M. tuberculosis (Riojas et al. 2018); a test enforces this
- labyrinthulids in the Chromista (Aplanochytrium), Dictydiaethalium in the Protozoa (genus_domain_move), and the
  rank suffix also between domains ('Acantharia {class}' next to the fungal genus Acantharia)
- devtools::test(): 1,582 expectations, 0 failures

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy build no longer depends on the previous build

- intrinsic_resistant is no input of the microorganisms build anymore (it is computed from it); the genera named in
  the interpretive rules are read from the rules instead
- the previous data set no longer makes genera relevant; Debaryomyces added to MO_RELEVANT_GENERA
- new run_after_microorganisms_build.R recreates microorganisms.groups, the EUCAST breakpoints and
  intrinsic_resistant in the right order, and the build runs it at its end
- reproduction_of_intrinsic_resistant.R uses devtools::load_all() instead of the installed package
- effect: 24 never released, not relevant COL records less; devtools::test(): 1,582 expectations, 0 failures

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* Taxonomy review report: summary updated to the second round

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

* MO code retirements: mark the 265 reviewed retirements as reviewed

The Graphium and v2.x Protozoa retirements were reviewed and accepted on 6 October 2026 (see the taxonomy review
report, section 5); 'NEEDS REVIEW' is replaced by 'reviewed by Matthijs S. Berends on 2026-10-06'.

Co-Authored-By: Claude Opus 5.5 <noreply@anthropic.com>

---------

Co-authored-by: Claude Opus 5.5 <noreply@anthropic.com>
2026-10-07 12:55:12 +02:00
Matthijs BerendsandClaude Opus 5.5 dab4c47e86 EUCAST import: blocking rows, note restrictions, PK-PD and parser fixes (#310)
Make the EUCAST Clinical Breakpoint Tables import (2019-2026) fail-safe:

- Add blocking rows (NA breakpoints, reason in `note`) where EUCAST gives
  no breakpoint for an organism (IE, "-", Note, brackets, "except"
  clauses, table scope), so as.sir() no longer falls back to broader taxa
- Apply restrictions from EUCAST notes via a curated rule table with a
  completeness guard (e.g. zone diameters for E. coli only)
- Import PK-PD (non-species related) breakpoints 2019-2023, H.
  parainfluenzae MIC breakpoints, and explicit screening thresholds from
  notes (high-level aminoglycosides, cefoxitin MIC, unidentified CoNS)
- Parser fixes: lost Staphylococcus sheets 2019/2020, note keys and
  bodies, struck-through cells, hidden sheets, missing disk contents,
  organism groups, site vocabulary, MIC dilution levels, off-scale
  breakpoints stored as 0.0001
- Keep EUCAST antifungal breakpoints 2019-2025 from WHONET; code WHONET
  streptomycin as STR1 instead of STR (streptoduocin)

Co-authored-by: Claude Opus 5.5 <noreply@anthropic.com>
2026-10-02 06:01:58 +02:00
dr. M.S. (Matthijs) Berends 9237bfbc19 (v3.0.1.9084) Fix breakpoint infer rules 2026-07-09 17:14:59 +02:00
Matthijs Berends 3f9f931777 (v3.0.1.9059) Update taxonomy of microorganisms 2026-06-23 01:38:13 +02:00
dr. M.S. (Matthijs) Berends e7780b6d5f (v3.0.1.9048) fix #275 2026-04-22 08:16:44 +02:00
dr. M.S. (Matthijs) Berends 26613d774b (v3.0.1.9042) add EUCAST breakpoint table v16 to interpretive_rules() 2026-04-02 11:42:19 +02:00
dr. M.S. (Matthijs) Berends 3a736bc484 (v3.0.1.9041) add breakpoints 2026 2026-03-30 10:01:49 +02:00
dr. M.S. (Matthijs) Berends 353eaa3f38 (v3.0.1.9033) add ionophores(), clorobiocin, aminocoumarins group 2026-03-09 11:57:36 +01:00
dr. M.S. (Matthijs) Berends daab605ca4 (v3.0.1.9028) fix unique CIDs 2026-03-06 18:53:42 +01:00
dr. M.S. (Matthijs) Berends b6211931f8 (v3.0.1.9022) add ceftibuten/avibactam (CTA), kasugamycin (KAS), ostreogrycin (OST), thiostrepton (THS), xeruborbactam (XER), zorbamycin (ZOR) 2026-03-03 15:41:08 +01:00
dr. M.S. (Matthijs) Berends 2df2911cf4 (v3.0.1.9018) fixes #249
updates AB groups
2026-01-16 10:57:03 +01:00
dr. M.S. (Matthijs) Berends cfbbfb4fa5 (v3.0.1.9007) fix #246 2026-01-06 23:08:50 +01:00
dr. M.S. (Matthijs) Berends ba30b08f76 (v3.0.1.9003) Add taniborbactam and cefepime/taniborbactam 2025-11-24 11:24:02 +01:00
dr. M.S. (Matthijs) Berends 10ba36821e (v3.0.0.9034) fix MycoBank synonyms 2025-09-18 13:58:34 +01:00
dr. M.S. (Matthijs) Berends 60bd631e1a (v3.0.0.9019) Fixes #229, #230, #227, #225 2025-09-01 16:56:55 +02:00
dr. M.S. (Matthijs) Berends e70f3de02e (v2.1.1.9286) deprecate antibiotics better, add ATC for ceftaroline 2025-06-01 11:54:40 +02:00
dr. M.S. (Matthijs) Berends fcd8b95e51 (v2.1.1.9272) mo codes sensititre 2025-05-04 18:50:25 +02:00
dr. M.S. (Matthijs) Berends a778eb9bcf (v2.1.1.9272) (v2.1.1.9271) add sensititre AB and animal codes 2025-05-04 16:40:08 +02:00
dr. M.S. (Matthijs) Berends dc5559a2c4 (v2.1.1.9270) Add support for Korean, fix ATCs 2025-05-04 14:24:43 +02:00
dr. M.S. (Matthijs) Berends 5e6bbdf3d1 (v2.1.1.9267) update ATCs 2025-05-01 11:48:49 +02:00
dr. M.S. (Matthijs) Berends 92316d5ddc (v2.1.1.9254) fix antimicrobial synonyms 2025-04-26 16:23:14 +02:00
dr. M.S. (Matthijs) Berends 9e64d7708e (v2.1.1.9248) unit test fix 2025-04-20 15:27:36 +02:00
dr. M.S. (Matthijs) Berends ea443f7483 (v2.1.1.9247) CLSI/EUCAST 2025! 2025-04-20 12:55:31 +02:00
dr. M.S. (Matthijs) Berends 49da312506 (v2.1.1.9228) repo cleaning 2025-03-28 11:17:49 +01:00