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@@ -1,6 +1,6 @@
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Package: AMR
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Version: 3.0.1.9041
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Date: 2026-03-30
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Version: 3.0.1.9039
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Date: 2026-03-19
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Title: Antimicrobial Resistance Data Analysis
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Description: Functions to simplify and standardise antimicrobial resistance (AMR)
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data analysis and to work with microbial and antimicrobial properties by
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@@ -63,8 +63,7 @@ Suggests:
|
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tidyselect,
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tinytest,
|
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vctrs,
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xml2,
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usethis
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xml2
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VignetteBuilder: knitr,rmarkdown
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URL: https://amr-for-r.org, https://github.com/msberends/AMR
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BugReports: https://github.com/msberends/AMR/issues
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14
NEWS.md
14
NEWS.md
@@ -1,7 +1,6 @@
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# AMR 3.0.1.9041
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# AMR 3.0.1.9039
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### New
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* Support for clinical breakpoints of 2026 of both CLSI and EUCAST, by adding all of their over 5,700 new clinical breakpoints to the `clinical_breakpoints` data set for usage in `as.sir()`. EUCAST 2026 is now the new default guideline for all MIC and disk diffusion interpretations.
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* Integration with the **tidymodels** framework to allow seamless use of SIR, MIC and disk data in modelling pipelines via `recipes`
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- `step_mic_log2()` to transform `<mic>` columns with log2, and `step_sir_numeric()` to convert `<sir>` columns to numeric
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- New `tidyselect` helpers:
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@@ -24,7 +23,6 @@
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* Fixed a bug in `as.ab()` where certain AB codes containing "PH" or "TH" (such as `ETH`, `MTH`, `PHE`, `PHN`, `STH`, `THA`, `THI1`) would incorrectly return `NA` when combined in a vector with any untranslatable value (#245)
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* Fixed a bug in `antibiogram()` for when no antimicrobials are set
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* Fixed a bug in `as.sir()` where for numeric input the arguments `S`, `I`, and `R` would not be considered (#244)
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* Fixed a bug in plotting MIC values when `keep_operators = "all"`
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* Fixed some foreign translations of antimicrobial drugs
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* Fixed a bug for printing column names to the console when using `mutate_at(vars(...), as.mic)` (#249)
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* Fixed a bug to disregard `NI` for susceptibility proportion functions
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@@ -32,7 +30,10 @@
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* Fixed SIR and MIC coercion of combined values, e.g. `as.sir("<= 0.002; S") ` or `as.mic("S; 0.002")` (#252)
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### Updates
|
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* Extensive `cli` integration for better message handling and clickable links in messages and warnings (#191, #265)
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* Replaced all bare backtick-quoted text in `message_()`, `warning_()`, and `stop_()` calls with proper cli inline markup (`{.arg}`, `{.cls}`, `{.fun}`, `{.pkg}`, `{.code}`); rewrote `print.ab` to use a cli named-vector with `*` bullets and code highlighting when cli is available
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* Added `format_inline_()` helper that formats a cli-markup string and returns it (rather than emitting it), using `cli::format_inline()` when available and `cli_to_plain()` otherwise; used this in `.onAttach` to replace the duplicated cli/non-cli startup message pattern
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* All inline `{variable}` / `{expression}` in messaging calls are now pre-evaluated via `paste0()`, so users without cli or glue never see raw template syntax
|
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* All `"in `funcname()`:"` patterns in `warning_()`/`message_()`/`stop_()` replaced with `{.help [{.fun funcname}](AMR::funcname)}` for clickable help links
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* `mdro()` now infers resistance for a _missing_ base drug column from an _available_ corresponding drug+inhibitor combination showing resistance (e.g., piperacillin is absent but required, while piperacillin/tazobactam available and resistant). Can be set with the new argument `infer_from_combinations`, which defaults to `TRUE` (#209). Note that this can yield a higher MDRO detection (which is a good thing as it has become more reliable).
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* `susceptibility()` and `resistance()` gained the argument `guideline`, which defaults to EUCAST, for interpreting the 'I' category correctly.
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* Added to the `antimicrobials` data set: cefepime/taniborbactam (`FTA`), ceftibuten/avibactam (`CTA`), clorobiocin (`CLB`), kasugamycin (`KAS`), ostreogrycin (`OST`), taniborbactam (`TAN`), thiostrepton (`THS`), xeruborbactam (`XER`), and zorbamycin (`ZOR`)
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@@ -47,6 +48,11 @@
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* Removed the `"inverse"` option, which has now become redundant
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* `ab_group()` now returns values consist with the AMR selectors (#246)
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* Added two new `NA` objects, `NA_ab_` and `NA_mo_`, analogous to base R's `NA_character_` and `NA_integer_`, for use in pipelines that require typed missing values
|
||||
* `message_()`, `warning_()`, `stop_()` now use `cli` markup when available, with plain-text fallback; removed `add_fn` parameter from `message_()`, `warning_()`, `word_wrap()`
|
||||
* New internal `cli_to_plain()` converts `cli` markup to plain text for non-cli path
|
||||
* All internal call sites updated to `cli` glue syntax
|
||||
* CI dev-version and old-tinytest workflows now only run on `main` branch pushes
|
||||
* Single-quoted literal values in messaging calls replaced with `{.val}`, `{.cls}`, `{.field}`, or `{.code}` markup throughout
|
||||
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||||
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# AMR 3.0.1
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@@ -253,9 +253,12 @@ search_type_in_df <- function(x, type, info = TRUE, add_col_prefix = TRUE) {
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# WHONET support
|
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found <- sort(colnames(x)[colnames_formatted %like_case% "^(specimen date|specimen_date|spec_date)"])
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if (!inherits(pm_pull(x, found), c("Date", "POSIXct"))) {
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stop_("Found column {.field ", font_bold(found), "} to be used as input for {.arg ", ifelse(add_col_prefix, "col_", ""), type,
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||||
"}, but this column contains no valid dates. Transform its values to valid dates first.",
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call = FALSE
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||||
stop(
|
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font_red(paste0(
|
||||
"Found column '", font_bold(found), "' to be used as input for `", ifelse(add_col_prefix, "col_", ""), type,
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||||
"`, but this column contains no valid dates. Transform its values to valid dates first."
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||||
)),
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||||
call. = FALSE
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||||
)
|
||||
}
|
||||
} else if (any(vapply(FUN.VALUE = logical(1), x, function(x) inherits(x, c("Date", "POSIXct"))))) {
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||||
@@ -302,7 +305,7 @@ search_type_in_df <- function(x, type, info = TRUE, add_col_prefix = TRUE) {
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# this column should contain logicals
|
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if (!is.logical(x[, found, drop = TRUE])) {
|
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message_(
|
||||
"Column {.field ", font_bold(found), "} found as input for {.arg ", ifelse(add_col_prefix, "col_", ""), type,
|
||||
"Column '", font_bold(found), "' found as input for {.arg ", ifelse(add_col_prefix, "col_", ""), type,
|
||||
"}, but this column does not contain {.code TRUE}/{.code FALSE} values and was ignored."
|
||||
)
|
||||
found <- NULL
|
||||
@@ -314,9 +317,9 @@ search_type_in_df <- function(x, type, info = TRUE, add_col_prefix = TRUE) {
|
||||
|
||||
if (!is.null(found) && isTRUE(info)) {
|
||||
if (message_not_thrown_before("search_in_type", type)) {
|
||||
msg <- paste0("Using column {.field ", font_bold(found), "} as input for {.arg ", ifelse(add_col_prefix, "col_", ""), type, "}.")
|
||||
msg <- paste0("Using column '", font_bold(found), "' as input for `", ifelse(add_col_prefix, "col_", ""), type, "`.")
|
||||
if (type %in% c("keyantibiotics", "keyantimicrobials", "specimen")) {
|
||||
msg <- paste(msg, "Use {.arg ", paste0(ifelse(add_col_prefix, "col_", ""), type), "= FALSE} to prevent this.")
|
||||
msg <- paste(msg, "Use", font_bold(paste0(ifelse(add_col_prefix, "col_", ""), type), "= FALSE"), "to prevent this.")
|
||||
}
|
||||
message_(msg)
|
||||
}
|
||||
@@ -380,6 +383,27 @@ pkg_is_available <- function(pkg, also_load = FALSE, min_version = NULL) {
|
||||
isTRUE(out)
|
||||
}
|
||||
|
||||
highlight_code <- function(code) {
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
cli::code_highlight(code)
|
||||
} else {
|
||||
code
|
||||
}
|
||||
}
|
||||
|
||||
# Format a cli-markup string for output, with a plain-text fallback when cli is
|
||||
# unavailable. Unlike message_() / warning_() / stop_(), this function returns
|
||||
# the formatted string rather than emitting it, so it can be passed to any
|
||||
# output function (e.g. packageStartupMessage()).
|
||||
format_inline_ <- function(...) {
|
||||
msg <- paste0(c(...), collapse = "")
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
cli::format_inline(msg)
|
||||
} else {
|
||||
cli_to_plain(msg, envir = parent.frame())
|
||||
}
|
||||
}
|
||||
|
||||
import_fn <- function(name, pkg, error_on_fail = TRUE) {
|
||||
if (isTRUE(error_on_fail)) {
|
||||
stop_ifnot_installed(pkg)
|
||||
@@ -405,30 +429,6 @@ import_fn <- function(name, pkg, error_on_fail = TRUE) {
|
||||
)
|
||||
}
|
||||
|
||||
highlight_code <- function(code) {
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
cli::code_highlight(code)
|
||||
} else {
|
||||
code
|
||||
}
|
||||
}
|
||||
|
||||
# Format a cli-markup string for output, with a plain-text fallback when cli is
|
||||
# unavailable. Unlike message_() / warning_() / stop_(), this function returns
|
||||
# the formatted string rather than emitting it, so it can be passed to any
|
||||
# output function (e.g. packageStartupMessage()).
|
||||
format_inline_ <- function(...) {
|
||||
msg <- paste0(c(...), collapse = "")
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
if (!cli::ansi_has_hyperlink_support()) {
|
||||
msg <- simplify_help_markup(msg)
|
||||
}
|
||||
cli::format_inline(msg)
|
||||
} else {
|
||||
cli_to_plain(msg, envir = parent.frame())
|
||||
}
|
||||
}
|
||||
|
||||
# Convert cli glue markup to plain text for the non-cli fallback path.
|
||||
# Called by message_(), warning_(), and stop_() when cli is not available.
|
||||
cli_to_plain <- function(msg, envir = parent.frame()) {
|
||||
@@ -552,46 +552,15 @@ word_wrap <- function(...,
|
||||
gsub("(\n| )+$", "", wrapped)
|
||||
}
|
||||
|
||||
simplify_help_markup <- function(msg) {
|
||||
# {.help [{.fun fn}](pkg::fn)} -> {.code fn()}
|
||||
# {.help [display](topic)} -> {.code display}
|
||||
msg <- gsub(
|
||||
"\\{\\.help \\[\\{\\.fun ([^}]+)\\}\\]\\([^)]+\\)\\}",
|
||||
"{.code \\1()}",
|
||||
msg,
|
||||
perl = TRUE
|
||||
)
|
||||
msg <- gsub(
|
||||
"\\{\\.help \\[([^]]+)\\]\\([^)]+\\)\\}",
|
||||
"{.code \\1}",
|
||||
msg,
|
||||
perl = TRUE
|
||||
)
|
||||
# {.topic [display](topic)} -> {.code ?display}
|
||||
msg <- gsub(
|
||||
"\\{\\.topic \\[([^]]+)\\]\\([^)]+\\)\\}",
|
||||
"{.code ?\\1}",
|
||||
msg,
|
||||
perl = TRUE
|
||||
)
|
||||
msg
|
||||
}
|
||||
|
||||
message_ <- function(...,
|
||||
appendLF = TRUE,
|
||||
as_note = TRUE) {
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
msg <- paste0(c(...), collapse = "")
|
||||
if (!cli::ansi_has_hyperlink_support()) {
|
||||
msg <- simplify_help_markup(msg)
|
||||
}
|
||||
if (isTRUE(as_note)) {
|
||||
cli::cli_inform(c("i" = msg), .envir = parent.frame())
|
||||
} else if (isTRUE(appendLF)) {
|
||||
cli::cli_inform(msg, .envir = parent.frame())
|
||||
} else {
|
||||
# This mirrors what rlang::inform() does internally (cat() to stderr), so it behaves consistently with cli_inform() output
|
||||
cat(format_inline_(msg), file = stderr())
|
||||
cli::cli_inform(msg, .envir = parent.frame())
|
||||
}
|
||||
} else {
|
||||
plain_msg <- cli_to_plain(paste0(c(...), collapse = ""), envir = parent.frame())
|
||||
@@ -604,9 +573,6 @@ warning_ <- function(...,
|
||||
call = FALSE) {
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
msg <- paste0(c(...), collapse = "")
|
||||
if (!cli::ansi_has_hyperlink_support()) {
|
||||
msg <- simplify_help_markup(msg)
|
||||
}
|
||||
cli::cli_warn(msg, .envir = parent.frame())
|
||||
} else {
|
||||
plain_msg <- cli_to_plain(paste0(c(...), collapse = ""), envir = parent.frame())
|
||||
@@ -619,9 +585,6 @@ warning_ <- function(...,
|
||||
# - wraps text to never break lines within words (plain-text fallback)
|
||||
stop_ <- function(..., call = TRUE) {
|
||||
msg <- paste0(c(...), collapse = "")
|
||||
if (!cli::ansi_has_hyperlink_support()) {
|
||||
msg <- simplify_help_markup(msg)
|
||||
}
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
if (isTRUE(call)) {
|
||||
call_obj <- sys.call(-1)
|
||||
@@ -1098,7 +1061,7 @@ get_current_data <- function(arg_name, call) {
|
||||
} else {
|
||||
examples <- ""
|
||||
}
|
||||
stop_("this function must be used inside a {.pkg dplyr} verb or {.cls data.frame} call",
|
||||
stop_("this function must be used inside a {.pkg dplyr} verb or {.code data.frame} call",
|
||||
examples,
|
||||
call = call
|
||||
)
|
||||
|
||||
30
R/ab.R
30
R/ab.R
@@ -484,7 +484,7 @@ as.ab <- function(x, flag_multiple_results = TRUE, language = get_AMR_locale(),
|
||||
}
|
||||
message_(
|
||||
"Antimicrobial translation was uncertain for ", examples,
|
||||
". If required, use {.help [{.fun add_custom_antimicrobials}](AMR::add_custom_antimicrobials)} to add custom entries."
|
||||
". If required, use `add_custom_antimicrobials()` to add custom entries."
|
||||
)
|
||||
}
|
||||
}
|
||||
@@ -529,7 +529,7 @@ NA_ab_ <- set_clean_class(NA_character_,
|
||||
#' @rawNamespace if(getRversion() >= "3.0.0") S3method(pillar::pillar_shaft, ab)
|
||||
pillar_shaft.ab <- function(x, ...) {
|
||||
out <- trimws(format(x))
|
||||
out[is.na(x)] <- pillar::style_na(NA)
|
||||
out[is.na(x)] <- font_na(NA)
|
||||
|
||||
# add the names to the drugs as mouse-over!
|
||||
if (in_rstudio()) {
|
||||
@@ -556,25 +556,25 @@ print.ab <- function(x, ...) {
|
||||
function_name <- attributes(x)$amr_selector
|
||||
if (pkg_is_available("cli", min_version = "3.0.0")) {
|
||||
cli::cli_inform(c(
|
||||
"i" = paste0("This {.cls ab} vector was retrieved using {.fun ", function_name, "}, which should normally be used inside a {.pkg dplyr} verb or {.cls data.frame} call, e.g.:"),
|
||||
paste0("\u00a0\u00a0", AMR_env$bullet_icon, " ", highlight_code(paste0("your_data %>% select(", function_name, "())"))),
|
||||
paste0("\u00a0\u00a0", AMR_env$bullet_icon, " ", highlight_code(paste0("your_data %>% select(column_a, column_b, ", function_name, "())"))),
|
||||
paste0("\u00a0\u00a0", AMR_env$bullet_icon, " ", highlight_code(paste0("your_data %>% filter(any(", function_name, "() == \"R\"))"))),
|
||||
paste0("\u00a0\u00a0", AMR_env$bullet_icon, " ", highlight_code(paste0("your_data[, ", function_name, "()]"))),
|
||||
paste0("\u00a0\u00a0", AMR_env$bullet_icon, " ", highlight_code(paste0("your_data[, c(\"column_a\", \"column_b\", ", function_name, "())]")))
|
||||
"i" = paste0("This {.cls ab} vector was retrieved using {.fun ", function_name, "}, which should normally be used inside a {.pkg dplyr} verb or {.code data.frame} call, e.g.:"),
|
||||
"*" = highlight_code(paste0("your_data %>% select(", function_name, "()")),
|
||||
"*" = highlight_code(paste0("your_data %>% select(column_a, column_b, ", function_name, "()")),
|
||||
"*" = highlight_code(paste0("your_data %>% filter(any(", function_name, "() == \"R\"))")),
|
||||
"*" = highlight_code(paste0("your_data[, ", function_name, "()]")),
|
||||
"*" = highlight_code(paste0("your_data[, c(\"column_a\", \"column_b\", ", function_name, "())]"))
|
||||
))
|
||||
} else {
|
||||
message(word_wrap(paste0(
|
||||
"This 'ab' vector was retrieved using `", function_name, "()`, which should normally be used inside a dplyr verb or data.frame call, e.g.:\n",
|
||||
"\u00a0\u00a0", AMR_env$bullet_icon, " your_data %>% select(", function_name, "())\n",
|
||||
"\u00a0\u00a0", AMR_env$bullet_icon, " your_data %>% select(column_a, column_b, ", function_name, "())\n",
|
||||
"\u00a0\u00a0", AMR_env$bullet_icon, " your_data %>% filter(any(", function_name, "() == \"R\"))\n",
|
||||
"\u00a0\u00a0", AMR_env$bullet_icon, " your_data[, ", function_name, "()]\n",
|
||||
"\u00a0\u00a0", AMR_env$bullet_icon, " your_data[, c(\"column_a\", \"column_b\", ", function_name, "())]"
|
||||
" ", AMR_env$bullet_icon, " your_data %>% select(", function_name, "())\n",
|
||||
" ", AMR_env$bullet_icon, " your_data %>% select(column_a, column_b, ", function_name, "())\n",
|
||||
" ", AMR_env$bullet_icon, " your_data %>% filter(any(", function_name, "() == \"R\"))\n",
|
||||
" ", AMR_env$bullet_icon, " your_data[, ", function_name, "()]\n",
|
||||
" ", AMR_env$bullet_icon, " your_data[, c(\"column_a\", \"column_b\", ", function_name, "())]"
|
||||
), as_note = TRUE))
|
||||
}
|
||||
}
|
||||
cat(format_inline_("Class {.cls ab}\n"))
|
||||
cat("Class 'ab'\n")
|
||||
print(as.character(x), quote = FALSE)
|
||||
}
|
||||
|
||||
@@ -718,7 +718,7 @@ get_translate_ab <- function(translate_ab) {
|
||||
} else {
|
||||
translate_ab <- tolower(translate_ab)
|
||||
stop_ifnot(translate_ab %in% colnames(AMR::antimicrobials),
|
||||
"invalid value for {.arg translate_ab}, this must be a column name of the {.help [antimicrobials](AMR::antimicrobials)} data set\n",
|
||||
"invalid value for {.arg translate_ab}, this must be a column name of the {.topic [antimicrobials](AMR::antimicrobials)} data set\n",
|
||||
"or {.code TRUE} (equals {.val name}) or {.code FALSE} to not translate at all.",
|
||||
call = FALSE
|
||||
)
|
||||
|
||||
@@ -678,7 +678,7 @@ not_intrinsic_resistant <- function(only_sir_columns = FALSE, col_mo = NULL, ver
|
||||
agents <- ab_in_data[ab_in_data %in% names(vars_df_R[which(vars_df_R)])]
|
||||
if (length(agents) > 0 &&
|
||||
message_not_thrown_before("not_intrinsic_resistant", sort(agents))) {
|
||||
agents_formatted <- paste0("{.field ", font_bold(agents, collapse = NULL), "}")
|
||||
agents_formatted <- paste0("'", font_bold(agents, collapse = NULL), "'")
|
||||
agents_names <- ab_name(names(agents), tolower = TRUE, language = NULL)
|
||||
need_name <- generalise_antibiotic_name(agents) != generalise_antibiotic_name(agents_names)
|
||||
agents_formatted[need_name] <- paste0(agents_formatted[need_name], " (", agents_names[need_name], ")")
|
||||
@@ -722,7 +722,7 @@ amr_select_exec <- function(function_name,
|
||||
if (any(untreatable %in% names(ab_in_data))) {
|
||||
if (message_not_thrown_before(function_name, "amr_class", "untreatable")) {
|
||||
warning_(
|
||||
"in {.help [{.fun ", function_name, "}](AMR::", function_name, ")}: some drugs were ignored since they cannot be used for treatment: ",
|
||||
"in `", function_name, "()`: some drugs were ignored since they cannot be used for treatment: ",
|
||||
vector_and(
|
||||
ab_name(names(ab_in_data)[names(ab_in_data) %in% untreatable],
|
||||
language = NULL,
|
||||
@@ -797,14 +797,14 @@ amr_select_exec <- function(function_name,
|
||||
if (only_treatable == TRUE) {
|
||||
if (message_not_thrown_before(function_name, "amr_class", "untreatable")) {
|
||||
message_(
|
||||
"in {.help [{.fun ", function_name, "}](AMR::", function_name, ")}: ",
|
||||
"in `", function_name, "()`: ",
|
||||
vector_and(
|
||||
paste0(
|
||||
ab_name(abx[abx %in% untreatable],
|
||||
language = NULL,
|
||||
tolower = TRUE
|
||||
),
|
||||
" ({.field ", font_bold(abx[abx %in% untreatable], collapse = NULL), "})"
|
||||
" (`", abx[abx %in% untreatable], "`)"
|
||||
),
|
||||
quotes = FALSE,
|
||||
sort = TRUE,
|
||||
@@ -837,10 +837,10 @@ amr_select_exec <- function(function_name,
|
||||
#' @export
|
||||
#' @noRd
|
||||
print.amr_selector <- function(x, ...) {
|
||||
warning_("It should never be needed to print an antimicrobial selector class. Are you using {.pkg data.table}? Then add the argument {.arg with = FALSE}, see our examples at {.help [{.fun amr_selector}](AMR::amr_selector)}.",
|
||||
warning_("It should never be needed to print an antimicrobial selector class. Are you using {.pkg data.table}? Then add the argument {.code with = FALSE}, see our examples at {.help [{.fun amr_selector}](AMR::amr_selector)}.",
|
||||
immediate = TRUE
|
||||
)
|
||||
cat(format_inline_("Class {.cls amr_selector}\n"))
|
||||
cat("Class 'amr_selector'\n")
|
||||
print(as.character(x), quote = FALSE)
|
||||
}
|
||||
|
||||
@@ -937,7 +937,7 @@ any.amr_selector_any_all <- function(..., na.rm = FALSE) {
|
||||
if (length(e1) > 1) {
|
||||
message_(
|
||||
"Assuming a filter on ", type, " ", length(e1), " ", gsub("[\\(\\)]", "", fn_name),
|
||||
". Wrap around {.fun all} or {.fun any} to prevent this note."
|
||||
". Wrap around `all()` or `any()` to prevent this note."
|
||||
)
|
||||
}
|
||||
}
|
||||
@@ -962,7 +962,7 @@ any.amr_selector_any_all <- function(..., na.rm = FALSE) {
|
||||
if (length(e1) > 1) {
|
||||
message_(
|
||||
"Assuming a filter on ", type, " ", length(e1), " ", gsub("[\\(\\)]", "", fn_name),
|
||||
". Wrap around {.fun all} or {.fun any} to prevent this note."
|
||||
". Wrap around `all()` or `any()` to prevent this note."
|
||||
)
|
||||
}
|
||||
}
|
||||
@@ -1071,12 +1071,12 @@ message_agent_names <- function(function_name, agents, ab_group = NULL, examples
|
||||
message_("No antimicrobial drugs of class '", ab_group, "' found", examples, ".")
|
||||
}
|
||||
} else {
|
||||
agents_formatted <- paste0("{.field ", font_bold(agents, collapse = NULL), "}")
|
||||
agents_formatted <- paste0("'", font_bold(agents, collapse = NULL), "'")
|
||||
agents_names <- ab_name(names(agents), tolower = TRUE, language = NULL)
|
||||
need_name <- generalise_antibiotic_name(agents) != generalise_antibiotic_name(agents_names)
|
||||
agents_formatted[need_name] <- paste0(agents_formatted[need_name], " (", agents_names[need_name], ")")
|
||||
message_(
|
||||
"For {.help [", function_name, "(",
|
||||
"For `", function_name, "(",
|
||||
ifelse(function_name == "amr_class",
|
||||
paste0("\"", amr_class_args, "\""),
|
||||
ifelse(!is.null(call),
|
||||
@@ -1084,7 +1084,7 @@ message_agent_names <- function(function_name, agents, ab_group = NULL, examples
|
||||
""
|
||||
)
|
||||
),
|
||||
")](AMR::", function_name, ")} using ",
|
||||
")` using ",
|
||||
ifelse(length(agents) == 1, "column ", "columns "),
|
||||
vector_and(agents_formatted, quotes = FALSE, sort = FALSE)
|
||||
)
|
||||
|
||||
@@ -180,7 +180,7 @@ atc_online_property <- function(atc_code,
|
||||
colnames(out) <- gsub("^atc.*", "atc", tolower(colnames(out)))
|
||||
|
||||
if (length(out) == 0) {
|
||||
message_("{.help [{.fun atc_online_property}](AMR::atc_online_property)}: no properties found for ATC ", atc_code[i], ". Please check {.href ", atc_url, " this WHOCC webpage}.")
|
||||
message_("in {.help [{.fun atc_online_property}](AMR::atc_online_property)}: no properties found for ATC ", atc_code[i], ". Please check {.href ", atc_url, " this WHOCC webpage}.")
|
||||
returnvalue[i] <- NA
|
||||
next
|
||||
}
|
||||
|
||||
6
R/av.R
6
R/av.R
@@ -511,8 +511,8 @@ is.av <- function(x) {
|
||||
#' @rawNamespace if(getRversion() >= "3.0.0") S3method(pillar::pillar_shaft, av)
|
||||
pillar_shaft.av <- function(x, ...) {
|
||||
out <- trimws(format(x))
|
||||
out[!is.na(x)] <- gsub("+", pillar::style_subtle("+"), out[!is.na(x)], fixed = TRUE)
|
||||
out[is.na(x)] <- pillar::style_na(NA)
|
||||
out[!is.na(x)] <- gsub("+", font_subtle("+"), out[!is.na(x)], fixed = TRUE)
|
||||
out[is.na(x)] <- font_na(NA)
|
||||
create_pillar_column(out, align = "left", min_width = 4)
|
||||
}
|
||||
|
||||
@@ -526,7 +526,7 @@ type_sum.av <- function(x, ...) {
|
||||
#' @export
|
||||
#' @noRd
|
||||
print.av <- function(x, ...) {
|
||||
cat(format_inline_("Class {.cls av}\n"))
|
||||
cat("Class 'av'\n")
|
||||
print(as.character(x), quote = FALSE)
|
||||
}
|
||||
|
||||
|
||||
@@ -84,7 +84,7 @@ bug_drug_combinations <- function(x,
|
||||
col_mo <- search_type_in_df(x = x, type = "mo")
|
||||
stop_if(is.null(col_mo), "{.arg col_mo} must be set")
|
||||
} else {
|
||||
stop_ifnot(col_mo %in% colnames(x), "column {.field ", font_bold(col_mo), "} ({.arg col_mo}) not found")
|
||||
stop_ifnot(col_mo %in% colnames(x), "column '", col_mo, "' ({.arg col_mo}) not found")
|
||||
}
|
||||
|
||||
x.bak <- x
|
||||
|
||||
@@ -166,5 +166,5 @@ clear_custom_antimicrobials <- function() {
|
||||
n2 <- nrow(AMR_env$AB_lookup)
|
||||
AMR_env$custom_ab_codes <- character(0)
|
||||
AMR_env$ab_previously_coerced <- AMR_env$ab_previously_coerced[which(AMR_env$ab_previously_coerced$ab %in% AMR_env$AB_lookup$ab), , drop = FALSE]
|
||||
message_("Cleared ", nr2char(n - n2), " custom record", ifelse(n - n2 > 1, "s", ""), " from the internal {.help [antimicrobials](AMR::antimicrobials)} data set.")
|
||||
message_("Cleared ", nr2char(n - n2), " custom record", ifelse(n - n2 > 1, "s", ""), " from the internal {.topic [antimicrobials](AMR::antimicrobials)} data set.")
|
||||
}
|
||||
|
||||
@@ -235,9 +235,9 @@ print.custom_mdro_guideline <- function(x, ...) {
|
||||
for (i in seq_len(length(x))) {
|
||||
rule <- x[[i]]
|
||||
rule$query <- format_custom_query_rule(rule$query)
|
||||
cat("\u00a0\u00a0", i, ". ", font_bold("If "), font_blue(rule$query), font_bold(" then: "), font_red(rule$value), "\n", sep = "")
|
||||
cat(" ", i, ". ", font_bold("If "), font_blue(rule$query), font_bold(" then: "), font_red(rule$value), "\n", sep = "")
|
||||
}
|
||||
cat("\u00a0\u00a0", i + 1, ". ", font_bold("Otherwise: "), font_red(paste0("Negative")), "\n", sep = "")
|
||||
cat(" ", i + 1, ". ", font_bold("Otherwise: "), font_red(paste0("Negative")), "\n", sep = "")
|
||||
cat("\nUnmatched rows will return ", font_red("NA"), ".\n", sep = "")
|
||||
if (isTRUE(attributes(x)$as_factor)) {
|
||||
cat("Results will be of class 'factor', with ordered levels: ", paste0(attributes(x)$values, collapse = " < "), "\n", sep = "")
|
||||
@@ -260,7 +260,7 @@ run_custom_mdro_guideline <- function(df, guideline, info) {
|
||||
)
|
||||
if (identical(qry, "error")) {
|
||||
warning_("in {.help [{.fun custom_mdro_guideline}](AMR::custom_mdro_guideline)}: rule ", i,
|
||||
" ({.code ", as.character(guideline[[i]]$query), "}) was ignored because of this error message: ",
|
||||
" (`", as.character(guideline[[i]]$query), "`) was ignored because of this error message: ",
|
||||
AMR_env$err_msg,
|
||||
call = FALSE
|
||||
)
|
||||
|
||||
@@ -128,7 +128,7 @@
|
||||
#' }
|
||||
add_custom_microorganisms <- function(x) {
|
||||
meet_criteria(x, allow_class = "data.frame")
|
||||
stop_ifnot("genus" %in% tolower(colnames(x)), "{.arg x} must contain column {.code genus}.")
|
||||
stop_ifnot("genus" %in% tolower(colnames(x)), "{.arg x} must contain column 'genus'.")
|
||||
|
||||
add_MO_lookup_to_AMR_env()
|
||||
|
||||
|
||||
8
R/disk.R
8
R/disk.R
@@ -119,9 +119,9 @@ as.disk <- function(x, na.rm = FALSE) {
|
||||
sort() %pm>%
|
||||
vector_and(quotes = TRUE)
|
||||
cur_col <- get_current_column()
|
||||
warning_("in {.help [{.fun as.disk}](AMR::as.disk)}: ", na_after - na_before, " result",
|
||||
warning_("in {.fun as.disk}: ", na_after - na_before, " result",
|
||||
ifelse(na_after - na_before > 1, "s", ""),
|
||||
ifelse(is.null(cur_col), "", paste0(" in column {.field ", font_bold(cur_col, collapse = NULL), "}")),
|
||||
ifelse(is.null(cur_col), "", paste0(" in column '", cur_col, "'")),
|
||||
" truncated (",
|
||||
round(((na_after - na_before) / length(x)) * 100),
|
||||
"%) that were invalid disk zones: ",
|
||||
@@ -162,7 +162,7 @@ is.disk <- function(x) {
|
||||
#' @rawNamespace if(getRversion() >= "3.0.0") S3method(pillar::pillar_shaft, disk)
|
||||
pillar_shaft.disk <- function(x, ...) {
|
||||
out <- trimws(format(x))
|
||||
out[is.na(x)] <- pillar::style_na(NA)
|
||||
out[is.na(x)] <- font_na(NA)
|
||||
create_pillar_column(out, align = "right", width = 2)
|
||||
}
|
||||
|
||||
@@ -170,7 +170,7 @@ pillar_shaft.disk <- function(x, ...) {
|
||||
#' @export
|
||||
#' @noRd
|
||||
print.disk <- function(x, ...) {
|
||||
cat(format_inline_("Class {.cls disk}\n"))
|
||||
cat("Class 'disk'\n")
|
||||
print(as.integer(x), quote = FALSE)
|
||||
}
|
||||
|
||||
|
||||
@@ -333,7 +333,7 @@ first_isolate <- function(x = NULL,
|
||||
check_columns_existance <- function(column, tblname = x) {
|
||||
if (!is.null(column)) {
|
||||
stop_ifnot(column %in% colnames(tblname),
|
||||
"Column {.code ", column, "} not found.",
|
||||
"Column '{column}' not found.",
|
||||
call = FALSE
|
||||
)
|
||||
}
|
||||
@@ -554,7 +554,7 @@ first_isolate <- function(x = NULL,
|
||||
format(sum(x$newvar_mo == "UNKNOWN", na.rm = TRUE),
|
||||
decimal.mark = decimal.mark, big.mark = big.mark
|
||||
),
|
||||
" isolates with a microbial ID 'UNKNOWN' (in column {.field ", font_bold(col_mo), "})"
|
||||
" isolates with a microbial ID 'UNKNOWN' (in column '", font_bold(col_mo), "')"
|
||||
)
|
||||
}
|
||||
x[which(x$newvar_mo == "UNKNOWN"), "newvar_first_isolate"] <- include_unknown
|
||||
@@ -565,7 +565,7 @@ first_isolate <- function(x = NULL,
|
||||
"Excluding ", format(sum(is.na(x$newvar_mo), na.rm = TRUE),
|
||||
decimal.mark = decimal.mark, big.mark = big.mark
|
||||
),
|
||||
" isolates with a microbial ID `NA` (in column {.field ", font_bold(col_mo), "})"
|
||||
" isolates with a microbial ID `NA` (in column '", font_bold(col_mo), "')"
|
||||
)
|
||||
}
|
||||
x[which(is.na(x$newvar_mo)), "newvar_first_isolate"] <- FALSE
|
||||
|
||||
@@ -86,7 +86,7 @@ guess_ab_col <- function(x = NULL, search_string = NULL, verbose = FALSE, only_s
|
||||
} else {
|
||||
if (isTRUE(verbose)) {
|
||||
message_(
|
||||
"Using column {.field ", font_bold(ab_result), "} as input for ", search_string,
|
||||
"Using column '", font_bold(ab_result), "' as input for ", search_string,
|
||||
" (", ab_name(search_string, language = NULL, tolower = TRUE), ")."
|
||||
)
|
||||
}
|
||||
@@ -146,7 +146,7 @@ get_column_abx <- function(x,
|
||||
meet_criteria(only_sir_columns, allow_class = "logical", has_length = 1)
|
||||
meet_criteria(sort, allow_class = "logical", has_length = 1)
|
||||
|
||||
if (isTRUE(info) && message_not_thrown_before("get_column_abx", colnames(x))) {
|
||||
if (isTRUE(info)) {
|
||||
message_("Auto-guessing columns suitable for analysis", appendLF = FALSE, as_note = FALSE)
|
||||
}
|
||||
|
||||
@@ -275,7 +275,7 @@ get_column_abx <- function(x,
|
||||
for (i in seq_len(length(out))) {
|
||||
if (isTRUE(verbose) && !out[i] %in% duplicates) {
|
||||
message_(
|
||||
"Using column {.field ", font_bold(out[i]), "} as input for ", names(out)[i],
|
||||
"Using column '", font_bold(out[i]), "' as input for ", names(out)[i],
|
||||
" (", ab_name(names(out)[i], tolower = TRUE, language = NULL), ")."
|
||||
)
|
||||
}
|
||||
@@ -284,7 +284,7 @@ get_column_abx <- function(x,
|
||||
if (names(out)[i] != already_set_as) {
|
||||
message_(
|
||||
paste0(
|
||||
"Column {.field ", font_bold(out[i]), "} will not be used for ",
|
||||
"Column '", font_bold(out[i]), "' will not be used for ",
|
||||
names(out)[i], " (", suppressMessages(ab_name(names(out)[i], tolower = TRUE, language = NULL, fast_mode = TRUE)), ")",
|
||||
", as this antimicrobial has already been set."
|
||||
)
|
||||
|
||||
@@ -329,7 +329,7 @@ interpretive_rules <- function(x,
|
||||
if (!"AMP" %in% names(cols_ab) && "AMX" %in% names(cols_ab)) {
|
||||
# ampicillin column is missing, but amoxicillin is available
|
||||
if (isTRUE(info)) {
|
||||
message_("Using column {.field ", font_bold(cols_ab[names(cols_ab) == "AMX"]), "} as input for ampicillin since many EUCAST rules depend on it.")
|
||||
message_("Using column '", cols_ab[names(cols_ab) == "AMX"], "' as input for ampicillin since many EUCAST rules depend on it.")
|
||||
}
|
||||
cols_ab <- c(cols_ab, c(AMP = unname(cols_ab[names(cols_ab) == "AMX"])))
|
||||
}
|
||||
@@ -510,8 +510,8 @@ interpretive_rules <- function(x,
|
||||
|
||||
## Set base to R where base + enzyme inhibitor is R ----
|
||||
rule_current <- paste0(
|
||||
ab_enzyme$base_name[i], " ({.field ", font_bold(col_base), "}) = R if ",
|
||||
tolower(ab_enzyme$enzyme_name[i]), " ({.field ", font_bold(col_enzyme), "}) = R"
|
||||
ab_enzyme$base_name[i], " (`", col_base, "`) = R if ",
|
||||
tolower(ab_enzyme$enzyme_name[i]), " (`", col_enzyme, "`) = R"
|
||||
)
|
||||
if (isTRUE(info)) {
|
||||
cat(word_wrap(rule_current,
|
||||
@@ -551,8 +551,8 @@ interpretive_rules <- function(x,
|
||||
|
||||
## Set base + enzyme inhibitor to S where base is S ----
|
||||
rule_current <- paste0(
|
||||
ab_enzyme$enzyme_name[i], " ({.field ", font_bold(col_enzyme), "}) = S if ",
|
||||
tolower(ab_enzyme$base_name[i]), " ({.field ", font_bold(col_base), "}) = S"
|
||||
ab_enzyme$enzyme_name[i], " (`", col_enzyme, "`) = S if ",
|
||||
tolower(ab_enzyme$base_name[i]), " (`", col_base, "`) = S"
|
||||
)
|
||||
|
||||
if (isTRUE(info)) {
|
||||
@@ -662,9 +662,9 @@ interpretive_rules <- function(x,
|
||||
if (ab %in% names(cols_ab) && !ab_s %in% names(cols_ab)) {
|
||||
if (isTRUE(info)) {
|
||||
message_(
|
||||
"Using column {.field ", font_bold(cols_ab[names(cols_ab) == ab]),
|
||||
"} as ", ab_name(ab_s, language = NULL, tolower = TRUE),
|
||||
" since a column {.code ", ab_s, "} is missing but required for the chosen rules"
|
||||
"Using column '", cols_ab[names(cols_ab) == ab],
|
||||
"' as ", ab_name(ab_s, language = NULL, tolower = TRUE),
|
||||
" since a column '", ab_s, "' is missing but required for the chosen rules"
|
||||
)
|
||||
}
|
||||
cols_ab <- c(cols_ab, stats::setNames(unname(cols_ab[names(cols_ab) == ab]), ab_s))
|
||||
@@ -806,7 +806,7 @@ interpretive_rules <- function(x,
|
||||
")$"
|
||||
)
|
||||
} else if (like_is_one_of != "like") {
|
||||
stop("invalid value for column {.field like.is.one_of}", call. = FALSE)
|
||||
stop("invalid value for column 'like.is.one_of'", call. = FALSE)
|
||||
}
|
||||
|
||||
if (is.na(source_antibiotics)) {
|
||||
|
||||
2
R/mdro.R
2
R/mdro.R
@@ -476,7 +476,7 @@ mdro <- function(x = NULL,
|
||||
if (!"AMP" %in% names(cols_ab) && "AMX" %in% names(cols_ab)) {
|
||||
# ampicillin column is missing, but amoxicillin is available
|
||||
if (isTRUE(info)) {
|
||||
message_("Using column {.field ", font_bold(cols_ab[names(cols_ab) == "AMX"]), "} as input for ampicillin since many MDRO rules depend on it.")
|
||||
message_("Using column '", cols_ab[names(cols_ab) == "AMX"], "' as input for ampicillin since many MDRO rules depend on it.")
|
||||
}
|
||||
cols_ab <- c(cols_ab, c(AMP = unname(cols_ab[names(cols_ab) == "AMX"])))
|
||||
}
|
||||
|
||||
27
R/mic.R
27
R/mic.R
@@ -72,7 +72,7 @@ COMMON_MIC_VALUES <- c(
|
||||
#' ```
|
||||
#' x <- random_mic(10)
|
||||
#' x
|
||||
#' #> Class <mic>
|
||||
#' #> Class 'mic'
|
||||
#' #> [1] 16 1 8 8 64 >=128 0.0625 32 32 16
|
||||
#'
|
||||
#' is.factor(x)
|
||||
@@ -89,7 +89,7 @@ COMMON_MIC_VALUES <- c(
|
||||
#'
|
||||
#' ```
|
||||
#' x[x > 4]
|
||||
#' #> Class <mic>
|
||||
#' #> Class 'mic'
|
||||
#' #> [1] 16 8 8 64 >=128 32 32 16
|
||||
#'
|
||||
#' df <- data.frame(x, hospital = "A")
|
||||
@@ -174,7 +174,7 @@ as.mic <- function(x, na.rm = FALSE, keep_operators = "all", round_to_next_log2
|
||||
keep_operators <- "none"
|
||||
}
|
||||
|
||||
if (any(is.mic(x)) && (keep_operators == "all" || !any(x %like% "[>=<]", na.rm = TRUE))) {
|
||||
if (is.mic(x) && (keep_operators == "all" || !any(x %like% "[>=<]", na.rm = TRUE))) {
|
||||
if (isTRUE(round_to_next_log2)) {
|
||||
x <- roundup_to_nearest_log2(x)
|
||||
}
|
||||
@@ -269,9 +269,9 @@ as.mic <- function(x, na.rm = FALSE, keep_operators = "all", round_to_next_log2
|
||||
sort() %pm>%
|
||||
vector_and(quotes = TRUE)
|
||||
cur_col <- get_current_column()
|
||||
warning_("in {.help [{.fun as.mic}](AMR::as.mic)}: ", na_after - na_before, " result",
|
||||
warning_("in {.fun as.mic}: ", na_after - na_before, " result",
|
||||
ifelse(na_after - na_before > 1, "s", ""),
|
||||
ifelse(is.null(cur_col), "", paste0(" in column {.field ", font_bold(cur_col, collapse = NULL), "}")),
|
||||
ifelse(is.null(cur_col), "", paste0(" in column '", cur_col, "'")),
|
||||
" truncated (",
|
||||
round(((na_after - na_before) / length(x)) * 100),
|
||||
"%) that were invalid MICs: ",
|
||||
@@ -322,12 +322,11 @@ NA_mic_ <- set_clean_class(factor(NA, levels = VALID_MIC_LEVELS, ordered = TRUE)
|
||||
#' @export
|
||||
rescale_mic <- function(x, mic_range, keep_operators = "edges", as.mic = TRUE, round_to_next_log2 = FALSE) {
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||||
meet_criteria(mic_range, allow_class = c("numeric", "integer", "logical", "mic"), has_length = 2, allow_NA = TRUE, allow_NULL = TRUE)
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||||
|
||||
if (is.numeric(mic_range)) {
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||||
mic_range <- trimws(format(mic_range, scientific = FALSE))
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mic_range <- gsub("[.]0+$", "", mic_range)
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||||
mic_range[mic_range == "NA"] <- NA_character_
|
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} else if (any(is.mic(mic_range))) {
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||||
} else if (is.mic(mic_range)) {
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mic_range <- as.character(mic_range)
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||||
}
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||||
stop_ifnot(
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||||
@@ -449,12 +448,16 @@ pillar_shaft.mic <- function(x, ...) {
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||||
crude_numbers <- as.double(x)
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||||
operators <- gsub("[^<=>]+", "", as.character(x))
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||||
# colourise operators
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||||
operators[!is.na(operators) & operators != ""] <- pillar::style_subtle(operators[!is.na(operators) & operators != ""])
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operators[!is.na(operators) & operators != ""] <- font_silver(operators[!is.na(operators) & operators != ""], collapse = NULL)
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||||
out <- trimws(paste0(operators, trimws(format(crude_numbers))))
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out[is.na(x)] <- pillar::style_na(NA)
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||||
out[is.na(x)] <- font_na(NA)
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||||
# make trailing zeroes less visible
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out[out %like% "[.]"] <- gsub("([.]?0+)$", pillar::style_subtle("\\1"), out[out %like% "[.]"], perl = TRUE)
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||||
|
||||
if (is_dark()) {
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||||
fn <- font_silver
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} else {
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||||
fn <- font_white
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||||
}
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||||
out[out %like% "[.]"] <- gsub("([.]?0+)$", fn("\\1"), out[out %like% "[.]"], perl = TRUE)
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||||
create_pillar_column(out, align = "right", width = max(nchar(font_stripstyle(out))))
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||||
}
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||||
|
||||
@@ -472,7 +475,7 @@ type_sum.mic <- function(x, ...) {
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||||
#' @export
|
||||
#' @noRd
|
||||
print.mic <- function(x, ...) {
|
||||
cat(format_inline_("Class {.cls mic}"))
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||||
cat("Class 'mic'")
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||||
if (!identical(levels(x), VALID_MIC_LEVELS)) {
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||||
cat(font_red(" with an outdated or altered structure - convert with `as.mic()` to update"))
|
||||
}
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||||
|
||||
28
R/mo.R
28
R/mo.R
@@ -249,7 +249,7 @@ as.mo <- function(x,
|
||||
if (length(which(ind)) > 0 && isTRUE(info) && message_not_thrown_before("as.mo_microorganisms.codes", is.na(out), toupper(x))) {
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||||
message_(
|
||||
"Retrieved value", ifelse(sum(ind) > 1, "s", ""),
|
||||
" from the {.help [microorganisms.codes](AMR::microorganisms.codes)} data set for ", vector_and(paste0("{.val ", toupper(x)[ind], "}"), quotes = FALSE), "."
|
||||
" from the `microorganisms.codes` data set for ", vector_and(toupper(x)[ind]), "."
|
||||
)
|
||||
}
|
||||
# From SNOMED ----
|
||||
@@ -502,7 +502,7 @@ as.mo <- function(x,
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||||
)
|
||||
if (any(out %in% AMR_env$MO_lookup$mo[match(post_Becker, AMR_env$MO_lookup$fullname)])) {
|
||||
if (message_not_thrown_before("as.mo", "becker")) {
|
||||
warning_("in {.help [{.fun as.mo}](AMR::as.mo)}: Becker ", font_italic("et al."), " (2014, 2019, 2020) does not contain these species named after their publication: ",
|
||||
warning_("in {.fun as.mo}: Becker ", font_italic("et al."), " (2014, 2019, 2020) does not contain these species named after their publication: ",
|
||||
vector_and(font_italic(gsub("Staphylococcus", "S.", post_Becker, fixed = TRUE), collapse = NULL), quotes = FALSE),
|
||||
". Categorisation to CoNS/CoPS was taken from the original scientific publication(s).",
|
||||
immediate = TRUE, call = FALSE
|
||||
@@ -648,13 +648,13 @@ pillar_shaft.mo <- function(x, ...) {
|
||||
add_MO_lookup_to_AMR_env()
|
||||
out <- trimws(format(x))
|
||||
# grey out the kingdom (part until first "_")
|
||||
out[!is.na(x)] <- gsub("^([A-Z]+_)(.*)", paste0(pillar::style_subtle("\\1"), "\\2"), out[!is.na(x)], perl = TRUE)
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||||
out[!is.na(x)] <- gsub("^([A-Z]+_)(.*)", paste0(font_subtle("\\1"), "\\2"), out[!is.na(x)], perl = TRUE)
|
||||
# and grey out every _
|
||||
out[!is.na(x)] <- gsub("_", pillar::style_subtle("_"), out[!is.na(x)])
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||||
out[!is.na(x)] <- gsub("_", font_subtle("_"), out[!is.na(x)])
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||||
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||||
# markup NA and UNKNOWN
|
||||
out[is.na(x)] <- pillar::style_na(" NA")
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||||
out[x == "UNKNOWN"] <- pillar::style_na(" UNKNOWN")
|
||||
out[is.na(x)] <- font_na(" NA")
|
||||
out[x == "UNKNOWN"] <- font_na(" UNKNOWN")
|
||||
|
||||
# markup manual codes
|
||||
out[x %in% AMR_env$MO_lookup$mo & !x %in% AMR::microorganisms$mo] <- font_blue(out[x %in% AMR_env$MO_lookup$mo & !x %in% AMR::microorganisms$mo], collapse = NULL)
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||||
@@ -673,20 +673,20 @@ pillar_shaft.mo <- function(x, ...) {
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(!is.null(df) && !all(unlist(df[, which(mo_cols), drop = FALSE]) %in% all_mos))) {
|
||||
# markup old mo codes
|
||||
out[!x %in% all_mos] <- font_italic(
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||||
pillar::style_na(x[!x %in% all_mos],
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||||
font_na(x[!x %in% all_mos],
|
||||
collapse = NULL
|
||||
),
|
||||
collapse = NULL
|
||||
)
|
||||
# throw a warning with the affected column name(s)
|
||||
if (!is.null(mo_cols)) {
|
||||
col <- paste0("Column ", vector_or(paste0("{.field ", font_bold(colnames(df)[mo_cols], collapse = NULL), "}"), quotes = TRUE, sort = FALSE))
|
||||
col <- paste0("Column ", vector_or(colnames(df)[mo_cols], quotes = TRUE, sort = FALSE))
|
||||
} else {
|
||||
col <- "The data"
|
||||
}
|
||||
warning_(
|
||||
col, " contains old MO codes (from a previous AMR package version). ",
|
||||
"Please update your MO codes with {.help [{.fun as.mo}](AMR::as.mo)}.",
|
||||
"Please update your MO codes with `as.mo()`.",
|
||||
call = FALSE
|
||||
)
|
||||
}
|
||||
@@ -783,7 +783,7 @@ get_skimmers.mo <- function(column) {
|
||||
#' @noRd
|
||||
print.mo <- function(x, print.shortnames = FALSE, ...) {
|
||||
add_MO_lookup_to_AMR_env()
|
||||
cat(format_inline_("Class {.cls mo}\n"))
|
||||
cat("Class 'mo'\n")
|
||||
x_names <- names(x)
|
||||
if (is.null(x_names) & print.shortnames == TRUE) {
|
||||
x_names <- tryCatch(mo_shortname(x, ...), error = function(e) NULL)
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||||
@@ -793,7 +793,7 @@ print.mo <- function(x, print.shortnames = FALSE, ...) {
|
||||
if (!all(x %in% c(AMR_env$MO_lookup$mo, NA))) {
|
||||
warning_(
|
||||
"Some MO codes are from a previous AMR package version. ",
|
||||
"Please update the MO codes with {.help [{.fun as.mo}](AMR::as.mo)}.",
|
||||
"Please update the MO codes with `as.mo()`.",
|
||||
call = FALSE
|
||||
)
|
||||
}
|
||||
@@ -827,7 +827,7 @@ as.data.frame.mo <- function(x, ...) {
|
||||
if (!all(x %in% c(AMR_env$MO_lookup$mo, NA))) {
|
||||
warning_(
|
||||
"The data contains old MO codes (from a previous AMR package version). ",
|
||||
"Please update your MO codes with {.help [{.fun as.mo}](AMR::as.mo)}."
|
||||
"Please update your MO codes with `as.mo()`."
|
||||
)
|
||||
}
|
||||
nm <- deparse1(substitute(x))
|
||||
@@ -977,8 +977,8 @@ print.mo_uncertainties <- function(x, n = 10, ...) {
|
||||
|
||||
out <- paste0(
|
||||
paste0(
|
||||
"", strrep(font_grey("-"), times = getOption("width", 100) - 1), "\n",
|
||||
"{.val ", x[i, ]$original_input, "}",
|
||||
"", strrep(font_grey("-"), times = getOption("width", 100)), "\n",
|
||||
'"', x[i, ]$original_input, '"',
|
||||
" -> ",
|
||||
paste0(
|
||||
font_bold(italicise(x[i, ]$fullname)),
|
||||
|
||||
@@ -270,6 +270,7 @@ mo_shortname <- function(x, language = get_AMR_locale(), keep_synonyms = getOpti
|
||||
}
|
||||
|
||||
|
||||
|
||||
#' @rdname mo_property
|
||||
#' @export
|
||||
mo_subspecies <- function(x, language = get_AMR_locale(), keep_synonyms = getOption("AMR_keep_synonyms", FALSE), ...) {
|
||||
@@ -1042,7 +1043,7 @@ find_mo_col <- function(fn) {
|
||||
)
|
||||
if (!is.null(df) && !is.null(mo) && is.data.frame(df)) {
|
||||
if (message_not_thrown_before(fn = fn)) {
|
||||
message_("Using column {.field ", font_bold(mo), "} as input for {.help [{.fun ", fn, "}](AMR::", fn, ")}")
|
||||
message_("Using column '", font_bold(mo), "' as input for {.help [{.fun ", fn, "}](AMR::", fn, ")}")
|
||||
}
|
||||
return(df[, mo, drop = TRUE])
|
||||
} else {
|
||||
|
||||
@@ -75,7 +75,7 @@
|
||||
#'
|
||||
#' ```
|
||||
#' as.mo("lab_mo_ecoli")
|
||||
#' #> Class <mo>
|
||||
#' #> Class 'mo'
|
||||
#' #> [1] B_ESCHR_COLI
|
||||
#'
|
||||
#' mo_genus("lab_mo_kpneumoniae")
|
||||
@@ -85,7 +85,7 @@
|
||||
#' as.mo(c("Escherichia coli", "E. coli", "lab_mo_ecoli"))
|
||||
#' #> NOTE: Translation to one microorganism was guessed with uncertainty.
|
||||
#' #> Use mo_uncertainties() to review it.
|
||||
#' #> Class <mo>
|
||||
#' #> Class 'mo'
|
||||
#' #> [1] B_ESCHR_COLI B_ESCHR_COLI B_ESCHR_COLI
|
||||
#' ```
|
||||
#'
|
||||
@@ -108,7 +108,7 @@
|
||||
#' #> NOTE: Updated mo_source file '/Users/me/mo_source.rds' (0.3 kB) from
|
||||
#' #> '/Users/me/Documents/ourcodes.xlsx' (9 kB), columns
|
||||
#' #> "Organisation XYZ" and "mo"
|
||||
#' #> Class <mo>
|
||||
#' #> Class 'mo'
|
||||
#' #> [1] B_ESCHR_COLI
|
||||
#'
|
||||
#' mo_genus("lab_Staph_aureus")
|
||||
@@ -289,7 +289,7 @@ check_validity_mo_source <- function(x, refer_to_name = "`reference_df`", stop_o
|
||||
}
|
||||
if (!"mo" %in% colnames(x)) {
|
||||
if (stop_on_error == TRUE) {
|
||||
stop_(refer_to_name, " must contain a column {.code mo}", call = FALSE)
|
||||
stop_(refer_to_name, " must contain a column {.field mo}", call = FALSE)
|
||||
} else {
|
||||
return(FALSE)
|
||||
}
|
||||
@@ -313,14 +313,14 @@ check_validity_mo_source <- function(x, refer_to_name = "`reference_df`", stop_o
|
||||
}
|
||||
if (colnames(x)[1] != "mo" && nrow(x) > length(unique(x[, 1, drop = TRUE]))) {
|
||||
if (stop_on_error == TRUE) {
|
||||
stop_(refer_to_name, " contains duplicate values in column {.field ", font_bold(colnames(x)[1]), "}", call = FALSE)
|
||||
stop_(refer_to_name, " contains duplicate values in column '", colnames(x)[1], "'", call = FALSE)
|
||||
} else {
|
||||
return(FALSE)
|
||||
}
|
||||
}
|
||||
if (colnames(x)[2] != "mo" && nrow(x) > length(unique(x[, 2, drop = TRUE]))) {
|
||||
if (stop_on_error == TRUE) {
|
||||
stop_(refer_to_name, " contains duplicate values in column {.field ", font_bold(colnames(x)[2]), "}", call = FALSE)
|
||||
stop_(refer_to_name, " contains duplicate values in column '", colnames(x)[2], "'", call = FALSE)
|
||||
} else {
|
||||
return(FALSE)
|
||||
}
|
||||
|
||||
43
R/plotting.R
43
R/plotting.R
@@ -262,11 +262,11 @@ create_scale_mic <- function(aest, keep_operators, mic_range = NULL, ...) {
|
||||
}
|
||||
mics <- rescale_mic(x = as.double(as.mic(df[[aest_val]])), keep_operators = "none", mic_range = NULL, as.mic = TRUE)
|
||||
if (!is.null(self$mic_values_rescaled) && any(mics < min(self$mic_values_rescaled, na.rm = TRUE) | mics > max(self$mic_values_rescaled, na.rm = TRUE), na.rm = TRUE)) {
|
||||
warning_("The value for {.field ", font_bold(aest_val), "} is outside the plotted MIC range, consider using/updating the {.arg mic_range} argument in {.fun scale_", aest, "_mic}.")
|
||||
warning_("The value for {.field ", aest_val, "} is outside the plotted MIC range, consider using/updating the {.arg mic_range} argument in {.fun scale_", aest, "_mic}.")
|
||||
}
|
||||
out[[aest_val]] <- log2(as.double(mics))
|
||||
} else {
|
||||
self$mic_values_rescaled <- rescale_mic(x = as.character(df[[aest]]), keep_operators = keep_operators, mic_range = mic_range, as.mic = TRUE)
|
||||
self$mic_values_rescaled <- rescale_mic(x = as.double(as.mic(df[[aest]])), keep_operators = keep_operators, mic_range = mic_range, as.mic = TRUE)
|
||||
# create new breaks and labels here
|
||||
lims <- range(self$mic_values_rescaled, na.rm = TRUE)
|
||||
# support inner and outer 'mic_range' settings (e.g., the data ranges 0.5-8 and 'mic_range' is set to 0.025-32)
|
||||
@@ -280,21 +280,11 @@ create_scale_mic <- function(aest, keep_operators, mic_range = NULL, ...) {
|
||||
ind_max <- which(COMMON_MIC_VALUES >= lims[2])[which.min(abs(COMMON_MIC_VALUES[COMMON_MIC_VALUES >= lims[2]] - lims[2]))] # Closest index where COMMON_MIC_VALUES >= lims[2]
|
||||
|
||||
self$mic_values_levels <- as.mic(COMMON_MIC_VALUES[ind_min:ind_max])
|
||||
if (length(unique(self$mic_values_levels)) > 1) {
|
||||
if (keep_operators == "all" && !all(self$mic_values_rescaled %in% self$mic_values_levels, na.rm = TRUE)) {
|
||||
self$mic_values_levels <- unique(sort(c(self$mic_values_levels, self$mic_values_rescaled)))
|
||||
|
||||
# collision = same log2 position, but different string labels
|
||||
log_positions <- log2(as.double(self$mic_values_levels))
|
||||
dup_positions <- log_positions[duplicated(log_positions) | duplicated(log_positions, fromLast = TRUE)]
|
||||
colliding_labels <- as.character(self$mic_values_levels)[log_positions %in% dup_positions]
|
||||
self$warn_keep_all_operators <- length(unique(colliding_labels)) > 1
|
||||
} else if (keep_operators == "edges") {
|
||||
self$mic_values_levels[1] <- paste0("<=", self$mic_values_levels[1])
|
||||
self$mic_values_levels[length(self$mic_values_levels)] <- paste0(">=", self$mic_values_levels[length(self$mic_values_levels)])
|
||||
}
|
||||
if (keep_operators %in% c("edges", "all") && length(unique(self$mic_values_levels)) > 1) {
|
||||
self$mic_values_levels[1] <- paste0("<=", self$mic_values_levels[1])
|
||||
self$mic_values_levels[length(self$mic_values_levels)] <- paste0(">=", self$mic_values_levels[length(self$mic_values_levels)])
|
||||
}
|
||||
|
||||
self$mic_values_log <- log2(as.double(self$mic_values_rescaled))
|
||||
|
||||
if (aest == "y" && "group" %in% colnames(df)) {
|
||||
@@ -322,26 +312,7 @@ create_scale_mic <- function(aest, keep_operators, mic_range = NULL, ...) {
|
||||
}
|
||||
scale$labels <- function(..., self) {
|
||||
if (is.null(self$mic_breaks_set)) {
|
||||
if (isTRUE(self$warn_keep_all_operators)) {
|
||||
lookup <- tapply(
|
||||
as.character(self$mic_values_rescaled),
|
||||
self$mic_values_log,
|
||||
function(x) paste(unique(x), collapse = ", ")
|
||||
)
|
||||
level_log <- as.character(log2(as.double(self$mic_values_levels)))
|
||||
|
||||
if (any(grepl(", ", lookup))) {
|
||||
warning_("Using {.arg keep_operators = \"all\"} caused MIC values with different operators to share the same log2 position on the axis. These have been combined into a single label (e.g., {.val ", lookup[grepl(", ", lookup)][1], "}).", call = FALSE)
|
||||
}
|
||||
|
||||
ifelse(
|
||||
level_log %in% names(lookup),
|
||||
lookup[level_log],
|
||||
as.character(self$mic_values_levels)
|
||||
)
|
||||
} else {
|
||||
self$mic_values_levels
|
||||
}
|
||||
self$mic_values_levels
|
||||
} else {
|
||||
breaks <- tryCatch(scale$breaks(), error = function(e) NULL)
|
||||
if (!is.null(breaks)) {
|
||||
@@ -441,7 +412,7 @@ create_scale_sir <- function(aesthetics, colours_SIR, language, eucast_I, ...) {
|
||||
|
||||
scale$labels <- function(x) {
|
||||
stop_ifnot(all(x %in% c(levels(NA_sir_), "SI", "IR", NA)),
|
||||
"Apply `scale_", aesthetics[1], "_sir()` to a variable of class {.cls sir}, see {.help [{.fun as.sir}](AMR::as.sir)}.",
|
||||
"Apply `scale_", aesthetics[1], "_sir()` to a variable of class 'sir', see {.help [{.fun as.sir}](AMR::as.sir)}.",
|
||||
call = FALSE
|
||||
)
|
||||
x <- as.character(x)
|
||||
|
||||
@@ -346,7 +346,7 @@ sir_confidence_interval <- function(...,
|
||||
if (n < minimum) {
|
||||
warning_("Introducing NA: ",
|
||||
ifelse(n == 0, "no", paste("only", n)),
|
||||
" results available for {.help [{.fun sir_confidence_interval}](AMR::sir_confidence_interval)} (whilst {.arg minimum = ", minimum, "}).",
|
||||
" results available for `sir_confidence_interval()` (`minimum` = ", minimum, ").",
|
||||
call = FALSE
|
||||
)
|
||||
if (is.character(out)) {
|
||||
|
||||
@@ -150,7 +150,7 @@ resistance_predict <- function(x,
|
||||
}
|
||||
stop_ifnot(
|
||||
col_date %in% colnames(x),
|
||||
"column {.code ", col_date, "} not found"
|
||||
"column '", col_date, "' not found"
|
||||
)
|
||||
|
||||
year <- function(x) {
|
||||
|
||||
99
R/sir.R
99
R/sir.R
@@ -471,7 +471,7 @@ is_sir_eligible <- function(x, threshold = 0.05) {
|
||||
if (!is.na(ab)) {
|
||||
# this is a valid antibiotic drug code
|
||||
message_(
|
||||
"Column {.field ", font_bold(cur_col), "} is SIR eligible (despite only having empty values), since it seems to be ",
|
||||
"Column '", font_bold(cur_col), "' is SIR eligible (despite only having empty values), since it seems to be ",
|
||||
ab_name(ab, language = NULL, tolower = TRUE), " (", ab, ")"
|
||||
)
|
||||
return(TRUE)
|
||||
@@ -601,7 +601,7 @@ as.sir.default <- function(x,
|
||||
ifelse(length(out7) > 0, paste0("7 as \"", out7, "\""), NA_character_),
|
||||
ifelse(length(out8) > 0, paste0("8 as \"", out8, "\""), NA_character_)
|
||||
)
|
||||
message_("{.help [{.fun as.sir}](AMR::as.sir)}: Interpreting input value ", vector_and(out[!is.na(out)], quotes = FALSE, sort = FALSE))
|
||||
message_("in {.help [{.fun as.sir}](AMR::as.sir)}: Interpreting input value ", vector_and(out[!is.na(out)], quotes = FALSE, sort = FALSE))
|
||||
}
|
||||
|
||||
if (na_before != na_after) {
|
||||
@@ -612,7 +612,7 @@ as.sir.default <- function(x,
|
||||
cur_col <- get_current_column()
|
||||
warning_("in {.help [{.fun as.sir}](AMR::as.sir)}: ", na_after - na_before, " result",
|
||||
ifelse(na_after - na_before > 1, "s", ""),
|
||||
ifelse(is.null(cur_col), "", paste0(" in column {.field ", font_bold(cur_col, collapse = NULL), "}")),
|
||||
ifelse(is.null(cur_col), "", paste0(" in column '", cur_col, "'")),
|
||||
" truncated (",
|
||||
round(((na_after - na_before) / length(x)) * 100),
|
||||
"%) that were invalid antimicrobial interpretations: ",
|
||||
@@ -759,10 +759,6 @@ as.sir.data.frame <- function(x,
|
||||
meet_criteria(max_cores, allow_class = c("numeric", "integer"), has_length = 1)
|
||||
x.bak <- x
|
||||
|
||||
if (isTRUE(info) && message_not_thrown_before("as.sir", "sir_interpretation_history")) {
|
||||
message_("Run {.help [{.fun sir_interpretation_history}](AMR::sir_interpretation_history)} afterwards to retrieve a logbook with all details of the breakpoint interpretations.\n\n")
|
||||
}
|
||||
|
||||
if (tryCatch(length(list(...)) > 0, error = function(e) TRUE)) {
|
||||
sel <- colnames(pm_select(x, ...))
|
||||
} else {
|
||||
@@ -839,7 +835,7 @@ as.sir.data.frame <- function(x,
|
||||
message_(
|
||||
"Assuming value", plural[1], " ",
|
||||
vector_and(col_values, quotes = TRUE),
|
||||
" in column ", paste0("{.field ", font_bold(col_specimen), "}"), " reflect", plural[2], " ", plural[3], "urinary tract infection", plural[1],
|
||||
" in column ", paste0("{.field ", col_specimen, "}"), " reflect", plural[2], " ", plural[3], "urinary tract infection", plural[1],
|
||||
".\n Use `as.sir(uti = FALSE)` to prevent this."
|
||||
)
|
||||
}
|
||||
@@ -861,7 +857,7 @@ as.sir.data.frame <- function(x,
|
||||
return(FALSE)
|
||||
}
|
||||
if (length(sel) == 0 || (length(sel) > 0 && ab %in% sel)) {
|
||||
ab_coerced <- suppressWarnings(as.ab(ab, info = FALSE))
|
||||
ab_coerced <- suppressWarnings(as.ab(ab, info = info))
|
||||
if (is.na(ab_coerced) || (length(sel) > 0 & !ab %in% sel)) {
|
||||
# not even a valid AB code
|
||||
return(FALSE)
|
||||
@@ -911,11 +907,6 @@ as.sir.data.frame <- function(x,
|
||||
}
|
||||
}
|
||||
|
||||
if (isTRUE(info)) {
|
||||
message_(as_note = FALSE) # empty line
|
||||
message_("Processing columns:", as_note = FALSE)
|
||||
}
|
||||
|
||||
run_as_sir_column <- function(i) {
|
||||
ab_col <- ab_cols[i]
|
||||
out <- list(result = NULL, log = NULL)
|
||||
@@ -978,12 +969,12 @@ as.sir.data.frame <- function(x,
|
||||
return(out)
|
||||
} else if (types[i] == "sir") {
|
||||
ab <- ab_col
|
||||
ab_coerced <- suppressWarnings(as.ab(ab, info = FALSE))
|
||||
ab_coerced <- suppressWarnings(as.ab(ab, info = info))
|
||||
show_message <- FALSE
|
||||
if (!all(x[, ab, drop = TRUE] %in% c("S", "SDD", "I", "R", "NI", NA), na.rm = TRUE)) {
|
||||
show_message <- TRUE
|
||||
if (isTRUE(info)) {
|
||||
message_("\u00a0\u00a0", AMR_env$bullet_icon, " Cleaning values in column ", paste0("{.field ", font_bold(ab), "}"), " (",
|
||||
message_("Cleaning values in column ", paste0("{.field ", ab, "}"), " (",
|
||||
ifelse(ab_coerced != toupper(ab), paste0(ab_coerced, ", "), ""),
|
||||
ab_name(ab_coerced, tolower = TRUE, info = info), ")... ",
|
||||
appendLF = FALSE,
|
||||
@@ -993,7 +984,7 @@ as.sir.data.frame <- function(x,
|
||||
} else if (!is.sir(x.bak[, ab, drop = TRUE])) {
|
||||
show_message <- TRUE
|
||||
if (isTRUE(info)) {
|
||||
message_("\u00a0\u00a0", AMR_env$bullet_icon, " Assigning class {.cls sir} to already clean column ", paste0("{.field ", font_bold(ab), "}"), " (",
|
||||
message_("Assigning class {.cls sir} to already clean column ", paste0("{.field ", ab, "}"), " (",
|
||||
ifelse(ab_coerced != toupper(ab), paste0(ab_coerced, ", "), ""),
|
||||
ab_name(ab_coerced, tolower = TRUE, language = NULL, info = info), ")... ",
|
||||
appendLF = FALSE,
|
||||
@@ -1003,7 +994,7 @@ as.sir.data.frame <- function(x,
|
||||
}
|
||||
result <- as.sir.default(x = as.character(x[, ab, drop = TRUE]))
|
||||
if (show_message == TRUE && isTRUE(info)) {
|
||||
message_(font_green_bg("\u00a0OK\u00a0"), as_note = FALSE)
|
||||
message(font_green_bg(" OK "))
|
||||
}
|
||||
out$result <- result
|
||||
out$log <- NULL
|
||||
@@ -1015,7 +1006,7 @@ as.sir.data.frame <- function(x,
|
||||
|
||||
if (isTRUE(parallel) && n_cores > 1 && length(ab_cols) > 1) {
|
||||
if (isTRUE(info)) {
|
||||
message_(as_note = FALSE)
|
||||
message()
|
||||
message_("Running in parallel mode using ", n_cores, " out of ", get_n_cores(Inf), " cores, on columns ", vector_and(font_bold(ab_cols, collapse = NULL), quotes = "'", sort = FALSE), "...", as_note = FALSE, appendLF = FALSE)
|
||||
}
|
||||
if (.Platform$OS.type == "windows" || getRversion() < "4.0.0") {
|
||||
@@ -1035,15 +1026,15 @@ as.sir.data.frame <- function(x,
|
||||
result_list <- parallel::mclapply(seq_along(ab_cols), run_as_sir_column, mc.cores = n_cores)
|
||||
}
|
||||
if (isTRUE(info)) {
|
||||
message_(font_green_bg("\u00aDONE\u00a"), as_note = FALSE)
|
||||
message_(as_note = FALSE)
|
||||
message_(font_green_bg(" DONE "), as_note = FALSE)
|
||||
message()
|
||||
message_("Run {.help [{.fun sir_interpretation_history}](AMR::sir_interpretation_history)} to retrieve a logbook with all details of the breakpoint interpretations.")
|
||||
}
|
||||
} else {
|
||||
# sequential mode (non-parallel)
|
||||
if (isTRUE(info) && n_cores > 1 && NROW(x) * NCOL(x) > 10000) {
|
||||
# give a note that parallel mode might be better
|
||||
message_(as_note = FALSE)
|
||||
message()
|
||||
message_("Running in sequential mode. Consider setting {.arg parallel} to {.code TRUE} to speed up processing on multiple cores.\n")
|
||||
}
|
||||
# this will contain a progress bar already
|
||||
@@ -1230,7 +1221,7 @@ as_sir_method <- function(method_short,
|
||||
host <- convert_host(host, lang = language)
|
||||
if (any(is.na(host) & !is.na(host.bak)) && isTRUE(info) && message_not_thrown_before("as.sir", "missing_hosts")) {
|
||||
warning_("The following animal host(s) could not be coerced: ", vector_and(host.bak[is.na(host) & !is.na(host.bak)]), immediate = TRUE)
|
||||
message_(as_note = FALSE) # new line
|
||||
message() # new line
|
||||
}
|
||||
# TODO add a switch to turn this off? In interactive sessions perhaps ask the user. Default should be On.
|
||||
# if (breakpoint_type == "animal" && isTRUE(info) && message_not_thrown_before("as.sir", "host_missing_breakpoints")) {
|
||||
@@ -1255,7 +1246,7 @@ as_sir_method <- function(method_short,
|
||||
|
||||
# get mo
|
||||
if (!is.null(current_df) && length(mo) == 1 && mo %in% colnames(current_df)) {
|
||||
mo_var_found <- paste0(" based on column {.field ", font_bold(mo), "}")
|
||||
mo_var_found <- paste0(" based on column '", font_bold(mo), "'")
|
||||
mo <- current_df[[mo]]
|
||||
} else if (length(mo) != length(x)) {
|
||||
mo_var_found <- ""
|
||||
@@ -1271,7 +1262,7 @@ as_sir_method <- function(method_short,
|
||||
silent = TRUE
|
||||
)
|
||||
if (!is.null(df) && !is.null(mo) && is.data.frame(df)) {
|
||||
mo_var_found <- paste0(" based on column {.field ", font_bold(mo), "}")
|
||||
mo_var_found <- paste0(" based on column '", font_bold(mo), "'")
|
||||
mo <- df[, mo, drop = TRUE]
|
||||
}
|
||||
},
|
||||
@@ -1324,7 +1315,7 @@ as_sir_method <- function(method_short,
|
||||
}
|
||||
|
||||
ab.bak <- trimws2(ab)
|
||||
ab <- suppressWarnings(as.ab(ab, info = FALSE))
|
||||
ab <- suppressWarnings(as.ab(ab, info = info))
|
||||
if (!is.null(list(...)$mo.bak)) {
|
||||
mo.bak <- list(...)$mo.bak
|
||||
} else {
|
||||
@@ -1360,12 +1351,12 @@ as_sir_method <- function(method_short,
|
||||
}
|
||||
if (isTRUE(add_intrinsic_resistance) && guideline_coerced %unlike% "EUCAST") {
|
||||
if (isTRUE(info) && message_not_thrown_before("as.sir", "intrinsic")) {
|
||||
message_("{.help [{.fun as.sir}](AMR::as.sir)}: using {.arg add_intrinsic_resistance} is only useful when using EUCAST guidelines, since the rules for intrinsic resistance are based on EUCAST.")
|
||||
message_("in {.help [{.fun as.sir}](AMR::as.sir)}: using {.arg add_intrinsic_resistance} is only useful when using EUCAST guidelines, since the rules for intrinsic resistance are based on EUCAST.")
|
||||
}
|
||||
}
|
||||
|
||||
# format agents ----
|
||||
agent_formatted <- paste0("{.field ", font_bold(ab.bak, collapse = NULL), "}")
|
||||
agent_formatted <- paste0("'", font_bold(ab.bak, collapse = NULL), "'")
|
||||
agent_name <- ab_name(ab, tolower = TRUE, language = NULL, info = info)
|
||||
same_ab <- generalise_antibiotic_name(ab) == generalise_antibiotic_name(agent_name)
|
||||
same_ab.bak <- generalise_antibiotic_name(ab.bak) == generalise_antibiotic_name(agent_name)
|
||||
@@ -1381,7 +1372,7 @@ as_sir_method <- function(method_short,
|
||||
)
|
||||
# this intro text will also be printed in the progress bar if the `progress` package is installed
|
||||
intro_txt <- paste0(
|
||||
"\u00a0\u00a0", AMR_env$bullet_icon, " Interpreting ", method_long, ": ", ifelse(isTRUE(list(...)$is_data.frame), "column ", ""),
|
||||
"Interpreting ", method_long, ": ", ifelse(isTRUE(list(...)$is_data.frame), "column ", ""),
|
||||
ifelse(length(unique(agent_formatted)) == 1, unique(agent_formatted), paste0(vector_and(agent_formatted, quotes = FALSE, sort = FALSE))),
|
||||
mo_var_found,
|
||||
ifelse(identical(reference_data, AMR::clinical_breakpoints),
|
||||
@@ -1399,7 +1390,7 @@ as_sir_method <- function(method_short,
|
||||
rise_warning <- FALSE
|
||||
rise_notes <- FALSE
|
||||
method_coerced <- toupper(method)
|
||||
ab_coerced <- as.ab(ab, info = FALSE)
|
||||
ab_coerced <- as.ab(ab, info = info)
|
||||
|
||||
if (identical(reference_data, AMR::clinical_breakpoints)) {
|
||||
breakpoints <- reference_data %pm>%
|
||||
@@ -1496,14 +1487,14 @@ as_sir_method <- function(method_short,
|
||||
# only print intro under 10 items, otherwise progressbar will print this and then it will be printed double
|
||||
message_(intro_txt, appendLF = FALSE, as_note = FALSE)
|
||||
}
|
||||
p <- progress_ticker(n = nrow(df_unique), n_min = 10, title = intro_txt, only_bar_percent = TRUE)
|
||||
p <- progress_ticker(n = nrow(df_unique), n_min = 10, title = font_blue(intro_txt), only_bar_percent = TRUE)
|
||||
has_progress_bar <- !is.null(import_fn("progress_bar", "progress", error_on_fail = FALSE)) && nrow(df_unique) >= 10
|
||||
on.exit(close(p))
|
||||
|
||||
if (nrow(breakpoints) == 0) {
|
||||
# apparently no breakpoints found
|
||||
if (isTRUE(info)) {
|
||||
message_(font_grey_bg(font_black(" NO BREAKPOINTS ")), as_note = FALSE)
|
||||
message(font_grey_bg(font_black(" NO BREAKPOINTS ")))
|
||||
}
|
||||
|
||||
load_mo_uncertainties(metadata_mo)
|
||||
@@ -1729,7 +1720,7 @@ as_sir_method <- function(method_short,
|
||||
pm_filter(uti == FALSE)
|
||||
notes_current <- paste0(
|
||||
notes_current, "\n",
|
||||
paste0("Breakpoints for UTI ", font_bold("and"), " non-UTI available for ", ab_formatted, " in ", mo_formatted, " - assuming ", site, ". Use argument `uti` to set which isolates are from urine. See `?as.sir`.")
|
||||
paste0("Breakpoints for UTI ", font_bold("and"), " non-UTI available for ", ab_formatted, " in ", mo_formatted, " - assuming ", site, ". Use argument {.arg uti} to set which isolates are from urine. See {.help [{.fun as.sir}](AMR::as.sir)}.")
|
||||
)
|
||||
} else if (nrow(breakpoints_current) > 1 && length(unique(breakpoints_current$site)) > 1 && all(breakpoints_current$uti == FALSE, na.rm = TRUE) && message_not_thrown_before("as.sir", "siteOther", mo_current, ab_current)) {
|
||||
# breakpoints for multiple body sites available
|
||||
@@ -1919,7 +1910,7 @@ as_sir_method <- function(method_short,
|
||||
host = vectorise_log_entry(breakpoints_current[, "host", drop = TRUE], length(rows)),
|
||||
input = vectorise_log_entry(as.character(input_clean), length(rows)),
|
||||
outcome = vectorise_log_entry(as.sir(new_sir), length(rows)),
|
||||
notes = font_stripstyle(notes_current),
|
||||
notes = font_stripstyle(notes_current), # vectorise_log_entry(paste0(font_stripstyle(notes_current), collapse = "\n"), length(rows)),
|
||||
guideline = vectorise_log_entry(guideline_current, length(rows)),
|
||||
ref_table = vectorise_log_entry(breakpoints_current[, "ref_tbl", drop = TRUE], length(rows)),
|
||||
uti = vectorise_log_entry(breakpoints_current[, "uti", drop = TRUE], length(rows)),
|
||||
@@ -1944,9 +1935,9 @@ as_sir_method <- function(method_short,
|
||||
notes <- notes[!trimws2(notes) %in% c("", NA_character_)]
|
||||
if (length(notes) > 0) {
|
||||
if (isTRUE(rise_warning)) {
|
||||
message_(font_rose_bg("\u00a0WARNING\u00a0"), as_note = FALSE)
|
||||
message(font_rose_bg(" WARNING "))
|
||||
} else {
|
||||
message_(font_yellow_bg("\u00a0NOTE\u00a0"), as_note = FALSE)
|
||||
message(font_yellow_bg(" NOTE "))
|
||||
}
|
||||
notes <- unique(notes)
|
||||
# if (isTRUE(verbose) || length(notes) == 1 || NROW(AMR_env$sir_interpretation_history) == 0) {
|
||||
@@ -1955,10 +1946,10 @@ as_sir_method <- function(method_short,
|
||||
message_(notes[i], as_note = FALSE)
|
||||
}
|
||||
} else {
|
||||
# message_(word_wrap("\u00a0\u00a0", AMR_env$bullet_icon, " There were multiple notes. Print or View `sir_interpretation_history()` to examine them, or use `as.sir(..., verbose = TRUE)` next time to directly print them here.", add_fn = font_black))
|
||||
# message(word_wrap(" ", AMR_env$bullet_icon, " There were multiple notes. Print or View `sir_interpretation_history()` to examine them, or use `as.sir(..., verbose = TRUE)` next time to directly print them here.", add_fn = font_black))
|
||||
}
|
||||
} else {
|
||||
message_(font_green_bg("\u00a0OK\u00a0"), as_note = FALSE)
|
||||
message(font_green_bg(" OK "))
|
||||
}
|
||||
}
|
||||
|
||||
@@ -2010,19 +2001,15 @@ pillar_shaft.sir <- function(x, ...) {
|
||||
if (has_colour()) {
|
||||
# colours will anyway not work when has_colour() == FALSE,
|
||||
# but then the indentation should also not be applied
|
||||
out[is.na(x)] <- pillar::style_subtle(" NA")
|
||||
out[x == "S"] <- font_green_bg(" S ") # has font_black internally
|
||||
out[x == "SDD"] <- font_green_lighter_bg(" SDD ") # has font_black internally
|
||||
if (getOption("AMR_guideline", "EUCAST")[1] == "EUCAST") {
|
||||
out[x == "I"] <- font_green_lighter_bg(" I ") # has font_black internally
|
||||
} else {
|
||||
out[x == "I"] <- font_orange_bg(" I ") # has font_black internally
|
||||
}
|
||||
out[x == "R"] <- font_rose_bg(" R ") # has font_black internally
|
||||
out[x == "NI"] <- font_grey_bg(font_black(" NI ", adapt = FALSE))
|
||||
out[x == "WT"] <- font_green_bg(" WT ") # has font_black internally
|
||||
out[x == "NWT"] <- font_rose_bg(" NWT ") # has font_black internally
|
||||
out[x == "NS"] <- font_rose_bg(" NS ") # has font_black internally
|
||||
out[is.na(x)] <- font_grey(" NA")
|
||||
out[x == "S"] <- font_green_bg(" S ")
|
||||
out[x == "SDD"] <- font_green_lighter_bg(" SDD ")
|
||||
out[x == "I"] <- font_orange_bg(" I ")
|
||||
out[x == "R"] <- font_rose_bg(" R ")
|
||||
out[x == "NI"] <- font_grey_bg(font_black(" NI "))
|
||||
out[x == "WT"] <- font_green_bg(font_black(" WT "))
|
||||
out[x == "NWT"] <- font_rose_bg(font_black(" NWT "))
|
||||
out[x == "NS"] <- font_rose_bg(font_black(" NS "))
|
||||
}
|
||||
create_pillar_column(out, align = "left", width = 5)
|
||||
}
|
||||
@@ -2080,10 +2067,10 @@ freq.sir <- function(x, ...) {
|
||||
# this prevents the requirement for putting the dependency in Imports:
|
||||
#' @rawNamespace if(getRversion() >= "3.0.0") S3method(skimr::get_skimmers, sir)
|
||||
get_skimmers.sir <- function(column) {
|
||||
# TODO #170 add here in AMR 3.1.0 details about guideline
|
||||
# TODO add here in AMR 3.1.0 details about guideline
|
||||
skimr::sfl(
|
||||
skim_type = "sir",
|
||||
# guideline = function(x) "EUCAST 2026", # or "Multiple"
|
||||
# guideline = function(x) "EUCAST 2025", # or "Multiple"
|
||||
# origin = function(x) "MIC", # or "Multiple"
|
||||
count_S = count_S,
|
||||
count_I = count_I,
|
||||
@@ -2100,7 +2087,7 @@ get_skimmers.sir <- function(column) {
|
||||
#' @noRd
|
||||
print.sir <- function(x, ...) {
|
||||
x_name <- deparse(substitute(x))
|
||||
cat(format_inline_("Class {.cls sir}\n"))
|
||||
cat("Class 'sir'\n")
|
||||
# TODO for #170
|
||||
# if (!is.null(attributes(x)$guideline) && !all(is.na(attributes(x)$guideline))) {
|
||||
# cat(font_blue(word_wrap("These values were interpreted using ",
|
||||
@@ -2239,13 +2226,13 @@ check_reference_data <- function(reference_data, .call_depth) {
|
||||
class_sir <- vapply(FUN.VALUE = character(1), AMR::clinical_breakpoints, function(x) paste0("<", class(x), ">", collapse = " and "))
|
||||
class_ref <- vapply(FUN.VALUE = character(1), reference_data, function(x) paste0("<", class(x), ">", collapse = " and "))
|
||||
if (!all(names(class_sir) == names(class_ref))) {
|
||||
stop_("{.arg reference_data} must have the same column names as the {.help [clinical_breakpoints](AMR::clinical_breakpoints)} data set.", call = .call_depth)
|
||||
stop_("{.arg reference_data} must have the same column names as the {.topic [clinical_breakpoints](AMR::clinical_breakpoints)} data set.", call = .call_depth)
|
||||
}
|
||||
if (!all(class_sir == class_ref)) {
|
||||
bad_col <- names(class_ref[class_sir != class_ref][1])
|
||||
bad_cls <- gsub("<|>", "", class_ref[class_sir != class_ref][1])
|
||||
exp_cls <- gsub("<|>", "", class_sir[class_sir != class_ref][1])
|
||||
stop_("{.arg reference_data} must be the same structure as the {.help [clinical_breakpoints](AMR::clinical_breakpoints)} data set. Column ", paste0("{.field ", font_bold(bad_col, collapse = NULL), "}"), " is of class ", paste0("{.cls ", bad_cls, "}"), ", but should be of class ", paste0("{.cls ", exp_cls, "}"), call = .call_depth)
|
||||
stop_("{.arg reference_data} must be the same structure as the {.topic [clinical_breakpoints](AMR::clinical_breakpoints)} data set. Column ", paste0("{.field ", bad_col, "}"), " is of class ", paste0("{.cls ", bad_cls, "}"), ", but should be of class ", paste0("{.cls ", exp_cls, "}"), call = .call_depth)
|
||||
}
|
||||
}
|
||||
}
|
||||
|
||||
@@ -204,7 +204,7 @@ sir_calc <- function(...,
|
||||
ifelse(denominator == 0, "no", paste("only", denominator)),
|
||||
" results available",
|
||||
data_vars,
|
||||
" (whilst {.arg minimum = ", minimum, "}).",
|
||||
" (`minimum` = ", minimum, ").",
|
||||
call = FALSE
|
||||
)
|
||||
fraction <- NA_real_
|
||||
|
||||
@@ -15,7 +15,7 @@ Overview:
|
||||
even WISCA
|
||||
- Provides the **full microbiological taxonomy** of ~79 000 distinct
|
||||
species and extensive info of ~620 antimicrobial drugs
|
||||
- Applies **CLSI 2011-2026** and **EUCAST 2011-2026** clinical and
|
||||
- Applies **CLSI 2011-2025** and **EUCAST 2011-2025** clinical and
|
||||
veterinary breakpoints, and ECOFFs, for MIC and disk zone
|
||||
interpretation
|
||||
- Corrects for duplicate isolates, **calculates** and **predicts** AMR
|
||||
|
||||
@@ -37,11 +37,6 @@ devtools::load_all()
|
||||
|
||||
# BE SURE TO RUN data-raw/_reproduction_scripts/reproduction_of_microorganisms.groups.R FIRST TO GET THE GROUPS!
|
||||
|
||||
# For non-interactive use
|
||||
if (!interactive()) {
|
||||
View <- glimpse
|
||||
}
|
||||
|
||||
# READ DATA ----
|
||||
|
||||
# files are retrieved from https://github.com/AClark-WHONET/AMRIE
|
||||
@@ -51,21 +46,21 @@ file_organisms <- file.path(github_repo, "Organisms.txt")
|
||||
file_breakpoints <- file.path(github_repo, "Breakpoints.txt")
|
||||
file_antibiotics <- file.path(github_repo, "Antibiotics.txt")
|
||||
|
||||
whonet_organisms_raw <- read_tsv(file_organisms, na = c("", "NA", "-"), show_col_types = FALSE, guess_max = Inf) |>
|
||||
whonet_organisms <- read_tsv(file_organisms, na = c("", "NA", "-"), show_col_types = FALSE, guess_max = Inf) |>
|
||||
# remove old taxonomic names
|
||||
filter(TAXONOMIC_STATUS == "C") |>
|
||||
mutate(ORGANISM_CODE = toupper(WHONET_ORG_CODE))
|
||||
|
||||
whonet_breakpoints_raw <- read_tsv(file_breakpoints, na = c("", "NA", "-"), show_col_types = FALSE, guess_max = Inf) |>
|
||||
whonet_breakpoints <- read_tsv(file_breakpoints, na = c("", "NA", "-"), show_col_types = FALSE, guess_max = Inf) |>
|
||||
filter(GUIDELINES %in% c("CLSI", "EUCAST"))
|
||||
|
||||
whonet_antibiotics_raw <- read_tsv(file_antibiotics, na = c("", "NA", "-"), show_col_types = FALSE, guess_max = Inf) |>
|
||||
whonet_antibiotics <- read_tsv(file_antibiotics, na = c("", "NA", "-"), show_col_types = FALSE, guess_max = Inf) |>
|
||||
arrange(WHONET_ABX_CODE) |>
|
||||
distinct(WHONET_ABX_CODE, .keep_all = TRUE)
|
||||
|
||||
# MICROORGANISMS WHONET CODES ----
|
||||
|
||||
whonet_organisms <- whonet_organisms_raw |>
|
||||
whonet_organisms <- whonet_organisms |>
|
||||
select(ORGANISM_CODE, ORGANISM, SPECIES_GROUP, GBIF_TAXON_ID) |>
|
||||
mutate(
|
||||
# this one was called Issatchenkia orientalis, but it should be:
|
||||
@@ -115,13 +110,6 @@ organisms <- matched |> transmute(code = toupper(ORGANISM_CODE), group = SPECIES
|
||||
mutate(name = mo_name(mo, keep_synonyms = TRUE)) |>
|
||||
arrange(code)
|
||||
|
||||
# self-defined codes in the MO table must be retained
|
||||
existing_codes <- microorganisms$fullname[microorganisms$fullname %like% ".* \\("]
|
||||
existing_codes <- gsub(".*\\((.*)\\)", "\\1", existing_codes)
|
||||
|
||||
organisms <- organisms |>
|
||||
filter(!code %in% existing_codes)
|
||||
|
||||
# some subspecies exist, while their upper species do not, add them as the species level:
|
||||
subspp <- organisms |>
|
||||
filter(mo_species(mo, keep_synonyms = TRUE) == mo_subspecies(mo, keep_synonyms = TRUE) &
|
||||
@@ -151,10 +139,9 @@ organisms <- organisms |> filter(code != "XXX")
|
||||
# 2023-07-08 SGM is also Strep gamma in WHONET, must only be Slowly-growing Mycobacterium
|
||||
# 2024-06-14 still the case
|
||||
# 2025-04-20 still the case
|
||||
# 2026-03-27 still the case, but fixed using `existing_codes` above
|
||||
organisms |> filter(code == "SGM")
|
||||
# organisms <- organisms |>
|
||||
# filter(!(code == "SGM" & name %like% "Streptococcus"))
|
||||
organisms <- organisms |>
|
||||
filter(!(code == "SGM" & name %like% "Streptococcus"))
|
||||
# this must be empty:
|
||||
organisms$code[organisms$code |> duplicated()]
|
||||
|
||||
@@ -175,7 +162,7 @@ microorganisms.codes2 <- microorganisms.codes |>
|
||||
# new codes:
|
||||
microorganisms.codes2$code[which(!microorganisms.codes2$code %in% microorganisms.codes$code)]
|
||||
mo_name(microorganisms.codes2$mo[which(!microorganisms.codes2$code %in% microorganisms.codes$code)], keep_synonyms = TRUE)
|
||||
microorganisms.codes <- microorganisms.codes2 |> distinct()
|
||||
microorganisms.codes <- microorganisms.codes2
|
||||
|
||||
# Run this part to update ASIARS-Net:
|
||||
# 2024-06-14: file not available anymore
|
||||
@@ -214,15 +201,10 @@ devtools::load_all()
|
||||
|
||||
# now that we have the correct MO codes, get the breakpoints and convert them
|
||||
|
||||
whonet_breakpoints_raw |>
|
||||
whonet_breakpoints |>
|
||||
count(GUIDELINES, BREAKPOINT_TYPE) |>
|
||||
pivot_wider(names_from = BREAKPOINT_TYPE, values_from = n) |>
|
||||
janitor::adorn_totals(where = c("row", "col"))
|
||||
whonet_breakpoints_raw |>
|
||||
filter(YEAR == format(Sys.Date(), "%Y")) |>
|
||||
count(GUIDELINES, YEAR, BREAKPOINT_TYPE) |>
|
||||
pivot_wider(names_from = BREAKPOINT_TYPE, values_from = n) |>
|
||||
janitor::adorn_totals(where = c("row", "col"))
|
||||
# compared to current
|
||||
AMR::clinical_breakpoints |>
|
||||
count(GUIDELINES = gsub("[^a-zA-Z]", "", guideline), type) |>
|
||||
@@ -231,7 +213,7 @@ AMR::clinical_breakpoints |>
|
||||
as.data.frame() |>
|
||||
janitor::adorn_totals(where = c("row", "col"))
|
||||
|
||||
breakpoints <- whonet_breakpoints_raw |>
|
||||
breakpoints <- whonet_breakpoints |>
|
||||
mutate(code = toupper(ORGANISM_CODE)) |>
|
||||
left_join(bind_rows(microorganisms.codes |> filter(!code %in% c("ALL", "GEN")),
|
||||
# GEN (Generic) and ALL (All) are PK/PD codes
|
||||
@@ -251,7 +233,7 @@ breakpoints <- breakpoints |>
|
||||
|
||||
# and these ones have unknown antibiotics according to WHONET itself:
|
||||
breakpoints |>
|
||||
filter(!WHONET_ABX_CODE %in% whonet_antibiotics_raw$WHONET_ABX_CODE) |>
|
||||
filter(!WHONET_ABX_CODE %in% whonet_antibiotics$WHONET_ABX_CODE) |>
|
||||
count(GUIDELINES, WHONET_ABX_CODE) |>
|
||||
mutate(ab = as.ab(WHONET_ABX_CODE, fast_mode = TRUE),
|
||||
ab_name = ab_name(ab))
|
||||
@@ -314,7 +296,7 @@ breakpoints_new[which(breakpoints_new$method == "DISK"), "breakpoint_R"] <- as.d
|
||||
# regarding animal breakpoints, CLSI has adults and foals for horses, but only for amikacin - only keep adult horses
|
||||
breakpoints_new |>
|
||||
filter(host %like% "foal") |>
|
||||
count(guideline, host, ab)
|
||||
count(guideline, host)
|
||||
breakpoints_new <- breakpoints_new |>
|
||||
filter(host %unlike% "foal") |>
|
||||
mutate(host = ifelse(host %like% "horse", "horse", host))
|
||||
@@ -322,7 +304,7 @@ breakpoints_new <- breakpoints_new |>
|
||||
# FIXES FOR WHONET ERRORS ----
|
||||
m <- unique(as.double(as.mic(levels(as.mic(1)))))
|
||||
|
||||
# WHONET has no >1024 but instead uses 1025, 513, and 129, so as.mic() cannot be used to clean.
|
||||
# WHONET has no >1024 but instead uses 1025, 513, etc, so as.mic() cannot be used to clean.
|
||||
# instead, raise these one higher valid MIC factor level:
|
||||
breakpoints_new |> filter(method == "MIC" & (!breakpoint_S %in% c(m, NA))) |> distinct(breakpoint_S)
|
||||
breakpoints_new |> filter(method == "MIC" & (!breakpoint_R %in% c(m, NA))) |> distinct(breakpoint_R)
|
||||
@@ -336,7 +318,6 @@ anyNA(breakpoints_new$breakpoint_S)
|
||||
|
||||
# a lot of R breakpoints are missing, but for CLSI this is required and can be set using as.sir(..., substitute_missing_r_breakpoint = TRUE/FALSE, ...)
|
||||
# 2025-04-20/ For EUCAST, this should not be the case, only happens to old guideline now it seems
|
||||
# 2026-03-27/ Now 2026 is in it as well, but making R same to S is fine
|
||||
breakpoints_new |>
|
||||
filter(method == "MIC" & guideline %like% "EUCAST" & is.na(breakpoint_R)) |>
|
||||
count(guideline)
|
||||
@@ -344,15 +325,10 @@ breakpoints_new[which(breakpoints_new$method == "MIC" & breakpoints_new$guidelin
|
||||
|
||||
|
||||
# fix streptococci in WHONET table of EUCAST: Strep A, B, C and G must only include these groups and not all streptococci:
|
||||
# 2026-03-27/ Only erroneous in EUCAST until 2024, it's fixed for 2025 and 2026, but we need to fix this historically too
|
||||
breakpoints_new$mo[breakpoints_new$guideline %like% "EUCAST" & breakpoints_new$mo == "B_STRPT" & breakpoints_new$ref_tbl %like% "^strep.* a.* b.*c.*g"] <- as.mo("B_STRPT_ABCG")
|
||||
breakpoints_new$mo[breakpoints_new$mo == "B_STRPT" & breakpoints_new$ref_tbl %like% "^strep.* a.* b.*c.*g"] <- as.mo("B_STRPT_ABCG")
|
||||
# Haemophilus same error (must only be H. influenzae)
|
||||
# 2026-03-27/ Only erroneous in EUCAST until 2024, it's fixed for 2025 and 2026, but we need to fix this historically too
|
||||
breakpoints_new$mo[breakpoints_new$guideline %like% "EUCAST" & breakpoints_new$mo == "B_HMPHL" & breakpoints_new$ref_tbl %like% "^h.* influenzae"] <- as.mo("B_HMPHL_INFL")
|
||||
breakpoints_new$mo[breakpoints_new$mo == "B_HMPHL" & breakpoints_new$ref_tbl %like% "^h.* influenzae"] <- as.mo("B_HMPHL_INFL")
|
||||
# EUCAST says that for H. parainfluenzae the H. influenza rules can be used, so add them
|
||||
breakpoints_new |>
|
||||
filter(method == "MIC" & guideline %like% "EUCAST" & mo %like% as.mo("B_HMPHL")) |>
|
||||
count(guideline, mo)
|
||||
breakpoints_new <- breakpoints_new |>
|
||||
bind_rows(
|
||||
breakpoints_new |>
|
||||
@@ -369,17 +345,6 @@ breakpoints_new |> filter(mo == as.mo("Streptococcus viridans") & ab == "GEH")
|
||||
breakpoints_new <- breakpoints_new |> filter(!(mo == as.mo("Streptococcus viridans") & ab == "GEN"))
|
||||
# Nitrofurantoin in Staph (EUCAST) only applies to S. saprophyticus, while WHONET has the DISK correct but the MIC on genus level
|
||||
breakpoints_new$mo[breakpoints_new$mo == "B_STPHY" & breakpoints_new$ab == "NIT" & breakpoints_new$guideline %like% "EUCAST"] <- as.mo("B_STPHY_SPRP")
|
||||
|
||||
# WHONET contains breakpoint for EUCAST that are not actually in EUCAST:
|
||||
# IPM in M. morganii is not in it since v10
|
||||
wrong <- with(breakpoints_new, guideline %like% "EUCAST" & ab == "IPM" & mo == as.mo("M. morganii") & ref_tbl != "ECOFF")
|
||||
breakpoints_new |> filter(wrong)
|
||||
breakpoints_new <- breakpoints_new |> filter(!wrong)
|
||||
# Breakpoints for COPS were part of EUCAST until v11
|
||||
wrong <- with(breakpoints_new, guideline %like% "EUCAST" & mo == as.mo("CoPS") & ref_tbl != "ECOFF")
|
||||
breakpoints_new |> filter(wrong)
|
||||
breakpoints_new <- breakpoints_new |> filter(!wrong)
|
||||
|
||||
# WHONET sets the 2023 breakpoints for SAM to MIC of 16/32 for Enterobacterales, should be MIC 8/32 like AMC (see issue #123 on github.com/msberends/AMR)
|
||||
# 2024-02-22/ fixed now
|
||||
|
||||
@@ -424,7 +389,7 @@ breakpoints_new |>
|
||||
filter(id %in% .$id[which(duplicated(id))]) |>
|
||||
arrange(desc(guideline)) |>
|
||||
View()
|
||||
# 2024-06-19/ mostly ECOFFs, but there's no explanation in the whonet_breakpoints_raw df, we have to remove duplicates
|
||||
# 2024-06-19/ mostly ECOFFs, but there's no explanation in the whonet_breakpoints file, we have to remove duplicates
|
||||
# 2025-04-20/ same, most important one seems M. tuberculosis in CLSI (also in 2025)
|
||||
breakpoints_new <- breakpoints_new |>
|
||||
distinct(guideline, type, host, method, site, mo, ab, uti, .keep_all = TRUE)
|
||||
@@ -433,9 +398,9 @@ breakpoints_new <- breakpoints_new |>
|
||||
# CHECKS AND SAVE TO PACKAGE ----
|
||||
|
||||
# check again
|
||||
breakpoints_new |> filter(guideline == "EUCAST 2026", ab == "AMC", mo == "B_[ORD]_ENTRBCTR", method == "MIC")
|
||||
breakpoints_new |> filter(guideline == "EUCAST 2025", ab == "AMC", mo == "B_[ORD]_ENTRBCTR", method == "MIC")
|
||||
# compare with current version
|
||||
clinical_breakpoints |> filter(guideline == "EUCAST 2025", ab == "AMC", mo == "B_[ORD]_ENTRBCTR", method == "MIC")
|
||||
clinical_breakpoints |> filter(guideline == "EUCAST 2024", ab == "AMC", mo == "B_[ORD]_ENTRBCTR", method == "MIC")
|
||||
|
||||
# must have "human" and "ECOFF"
|
||||
breakpoints_new |> filter(mo == "B_STRPT_PNMN", ab == "AMP", guideline == "EUCAST 2020", method == "MIC")
|
||||
|
||||
@@ -1 +1 @@
|
||||
c43a990cf91f959913d207e5a85e2bd5
|
||||
c7062e60fa4fbc2eee233044d15903ce
|
||||
|
||||
Binary file not shown.
Binary file not shown.
Binary file not shown.
Binary file not shown.
Binary file not shown.
File diff suppressed because it is too large
Load Diff
Binary file not shown.
Binary file not shown.
Binary file not shown.
Binary file not shown.
Binary file not shown.
Binary file not shown.
@@ -2832,7 +2832,6 @@
|
||||
"FU-" "B_FSBCTR"
|
||||
"FUA.SP" "F_FUSRM"
|
||||
"FUL" "B_FSBCTR_ULCR"
|
||||
"FUO" "F_FUSRM_OXYS"
|
||||
"FUR" "F_FUSRM"
|
||||
"FUROXY" "F_FUSRM_OXYS"
|
||||
"FURPET" "F_FUSRM_PTRL"
|
||||
@@ -2937,7 +2936,6 @@
|
||||
"GLO.SP" "B_GLBCT"
|
||||
"GLOSAN" "B_GLBCT_SNGN"
|
||||
"GLOSPP" "B_GLBCT"
|
||||
"GLS" "B_GLSSR"
|
||||
"GM+" "B_GRAMP"
|
||||
"GM-" "B_GRAMN"
|
||||
"GMO" "B_GEMLL_MRBL"
|
||||
@@ -3028,6 +3026,7 @@
|
||||
"HABSPP" "B_HMTBC"
|
||||
"HAC" "B_AGGRG_ACTN"
|
||||
"HACEK" "B_HACEK"
|
||||
"HACEK" "B_HACEK"
|
||||
"HAE" "B_HMPHL"
|
||||
"HAE.SP" "B_HMPHL"
|
||||
"HAEAEG" "B_HMPHL_AEGY"
|
||||
@@ -3123,7 +3122,7 @@
|
||||
"HPL" "B_HMPHL_PRPH"
|
||||
"HPO" "F_OGATA"
|
||||
"HPOSPP" "F_HNDRS_ASTR"
|
||||
"HPR" "B_GLSSR_PRSS"
|
||||
"HPR" "B_HMPHL_PRSS"
|
||||
"HPU" "B_HLCBCT_PLLR"
|
||||
"HPY" "B_HLCBCT_PYLR"
|
||||
"HRB" "B_HRBSP"
|
||||
@@ -3472,7 +3471,6 @@
|
||||
"LQU" "B_LGNLL_QTRN"
|
||||
"LRC" "B_LPTSP_INTR"
|
||||
"LRE" "B_LCTBC_RETR"
|
||||
"LRF" "B_LCTCC_RFFN"
|
||||
"LRI" "B_LMNRL_RCHR"
|
||||
"LRU" "B_LGNLL_RBRL"
|
||||
"LSA" "B_LCTBC_SLVR"
|
||||
@@ -3762,7 +3760,6 @@
|
||||
"MNE" "B_MYCBC_NERM"
|
||||
"MNL" "B_MRXLL_NNLQ"
|
||||
"MNO" "B_MYCBC_NNCH"
|
||||
"MNT" "B_MYCBC"
|
||||
"MNV" "B_MNNHM_VRGN"
|
||||
"MO-" "B_MRXLL"
|
||||
"MO.BOV" "B_MRXLL_BOVS"
|
||||
@@ -4298,7 +4295,6 @@
|
||||
"PAT.SP" "B_PANTO"
|
||||
"PAU" "B_SLMNL_ENTR_ENTR"
|
||||
"PAV" "B_AVBCT_AVIM"
|
||||
"PBA" "B_PSDCL_ALBA"
|
||||
"PBC" "B_PRVTL_BCCL"
|
||||
"PBE" "B_PSTRL_BTTY"
|
||||
"PBI" "B_PRBCT"
|
||||
@@ -4595,7 +4591,6 @@
|
||||
"PSA" "F_PSDLL"
|
||||
"PSA.SP" "F_PSDLL"
|
||||
"PSASPP" "F_PSDLL"
|
||||
"PSB" "B_PSDCL"
|
||||
"PSC" "F_PSDCH"
|
||||
"PSCSPP" "B_PSDCL"
|
||||
"PSD" "B_STPHY_PSDN"
|
||||
@@ -4711,7 +4706,6 @@
|
||||
"RAH.SP" "B_RHNLL"
|
||||
"RAHAQU" "B_RHNLL_AQTL"
|
||||
"RAHSPP" "B_RHNLL"
|
||||
"RAI" "B_RLSTN_INSD"
|
||||
"RAK" "B_RTTSA_AKAR"
|
||||
"RAL" "B_RLSTN"
|
||||
"RAL.SP" "B_RLSTN"
|
||||
@@ -4806,7 +4800,6 @@
|
||||
"ROD" "B_RDNTB"
|
||||
"RODPNE" "B_RDNTB_PNMT"
|
||||
"RODSPP" "B_RDNTB"
|
||||
"ROK" "B_ROTHI_KRST"
|
||||
"ROL" "F_RHZPS_MCRS"
|
||||
"ROM" "B_RSMNS"
|
||||
"ROMMUC" "B_RSMNS"
|
||||
@@ -5049,10 +5042,8 @@
|
||||
"SAV" "B_SLMNL_ARCH"
|
||||
"SB2" "B_STRPT_BOVS"
|
||||
"SBA" "B_SLMNL_BRLL"
|
||||
"SBC" "B_SLBCL"
|
||||
"SBE" "B_SHWNL_BNTH"
|
||||
"SBG" "B_SLMNL_BNGR"
|
||||
"SBI" "B_SLBCL_SLVS"
|
||||
"SBL" "B_SLMNL_BLCK"
|
||||
"SBM" "B_SLMNL_BVSM"
|
||||
"SBN" "B_SLMNL_BBRG"
|
||||
@@ -5087,7 +5078,6 @@
|
||||
"SCS" "F_SCLCB_CNST"
|
||||
"SCT" "B_STRPT_CNST"
|
||||
"SCU" "B_STPHY_CRNS"
|
||||
"SCV" "F_SCPLR_VCLS"
|
||||
"SCY" "F_SCYTL"
|
||||
"SCYSPP" "F_SCYTL"
|
||||
"SD1" "B_SHGLL_DYSN"
|
||||
@@ -5666,7 +5656,6 @@
|
||||
"TAYSPP" "B_TYLRL"
|
||||
"TBE" "F_GTRCH_RDLL"
|
||||
"TBESPP" "F_TRCHS"
|
||||
"TBH" "F_TRCHP_BNHM"
|
||||
"TBN" "B_TRPRL_BRNR"
|
||||
"TCA" "F_DBRYM_CHVL"
|
||||
"TCASPP" "F_CANDD"
|
||||
@@ -5852,8 +5841,6 @@
|
||||
"TYASPP" "F_TRCHP"
|
||||
"TYE" "P_TRYPN_JNSN"
|
||||
"TYI" "F_TRCHP_INDT"
|
||||
"TYM" "B_TRPHR"
|
||||
"TYW" "B_TRPHR_WHPP"
|
||||
"ULO" "F_ULCLD"
|
||||
"UNK" "UNKNOWN"
|
||||
"UPEC" "B_ESCHR_COLI"
|
||||
@@ -5863,7 +5850,6 @@
|
||||
"UREPAR" "B_URPLS_PRVM"
|
||||
"URESPP" "B_URPLS"
|
||||
"UREURE" "B_URPLS_URLY"
|
||||
"URP" "B_URPLS_PRVM"
|
||||
"UUR" "B_URPLS_URLY"
|
||||
"V.ALG" "B_VIBRI_ALGN"
|
||||
"V.CHO" "B_VIBRI_CHLR"
|
||||
|
||||
Binary file not shown.
@@ -1 +1 @@
|
||||
6ef98bb1bcd27052fde453bb12c0b285
|
||||
986d5110a46bbf297ebaeb4dd5179fff
|
||||
|
||||
Binary file not shown.
Binary file not shown.
Binary file not shown.
Binary file not shown.
32
index.md
32
index.md
@@ -10,7 +10,7 @@
|
||||
even WISCA
|
||||
- Provides the **full microbiological taxonomy** of ~79 000 distinct
|
||||
species and extensive info of ~620 antimicrobial drugs
|
||||
- Applies **CLSI 2011-2026** and **EUCAST 2011-2026** clinical and
|
||||
- Applies **CLSI 2011-2025** and **EUCAST 2011-2025** clinical and
|
||||
veterinary breakpoints, and ECOFFs, for MIC and disk zone
|
||||
interpretation
|
||||
- Corrects for duplicate isolates, **calculates** and **predicts** AMR
|
||||
@@ -68,7 +68,7 @@ species**](./reference/microorganisms.html) (updated June 2024) and all
|
||||
drugs**](./reference/antimicrobials.html) by name and code (including
|
||||
ATC, EARS-Net, ASIARS-Net, PubChem, LOINC and SNOMED CT), and knows all
|
||||
about valid SIR and MIC values. The integral clinical breakpoint
|
||||
guidelines from CLSI 2011-2026 and EUCAST 2011-2026 are included, even
|
||||
guidelines from CLSI 2011-2025 and EUCAST 2011-2025 are included, even
|
||||
with epidemiological cut-off (ECOFF) values. It supports and can read
|
||||
any data format, including WHONET data. This package works on Windows,
|
||||
macOS and Linux with all versions of R since R-3.0 (April 2013). **It
|
||||
@@ -171,14 +171,14 @@ example_isolates %>%
|
||||
select(bacteria,
|
||||
aminoglycosides(),
|
||||
carbapenems())
|
||||
#> ℹ Using column mo as input for `mo_fullname()`
|
||||
#> ℹ Using column mo as input for `mo_is_gram_negative()`
|
||||
#> ℹ Using column mo as input for `mo_is_intrinsic_resistant()`
|
||||
#> ℹ Using column 'mo' as input for `mo_fullname()`
|
||||
#> ℹ Using column 'mo' as input for `mo_is_gram_negative()`
|
||||
#> ℹ Using column 'mo' as input for `mo_is_intrinsic_resistant()`
|
||||
#> ℹ Determining intrinsic resistance based on 'EUCAST Expected Resistant
|
||||
#> Phenotypes' v1.2 (2023). This note will be shown once per session.
|
||||
#> ℹ For `aminoglycosides()` using columns GEN (gentamicin), TOB (tobramycin), AMK
|
||||
#> (amikacin), and KAN (kanamycin)
|
||||
#> ℹ For `carbapenems()` using columns IPM (imipenem) and MEM (meropenem)
|
||||
#> ℹ For `aminoglycosides()` using columns 'GEN' (gentamicin), 'TOB'
|
||||
#> (tobramycin), 'AMK' (amikacin), and 'KAN' (kanamycin)
|
||||
#> ℹ For `carbapenems()` using columns 'IPM' (imipenem) and 'MEM' (meropenem)
|
||||
#> # A tibble: 35 × 7
|
||||
#> bacteria GEN TOB AMK KAN IPM MEM
|
||||
#> <chr> <sir> <sir> <sir> <sir> <sir> <sir>
|
||||
@@ -215,9 +215,9 @@ output format automatically (such as markdown, LaTeX, HTML, etc.).
|
||||
``` r
|
||||
antibiogram(example_isolates,
|
||||
antimicrobials = c(aminoglycosides(), carbapenems()))
|
||||
#> ℹ For `aminoglycosides()` using columns GEN (gentamicin), TOB (tobramycin), AMK
|
||||
#> (amikacin), and KAN (kanamycin)
|
||||
#> ℹ For `carbapenems()` using columns IPM (imipenem) and MEM (meropenem)
|
||||
#> ℹ For `aminoglycosides()` using columns 'GEN' (gentamicin), 'TOB'
|
||||
#> (tobramycin), 'AMK' (amikacin), and 'KAN' (kanamycin)
|
||||
#> ℹ For `carbapenems()` using columns 'IPM' (imipenem) and 'MEM' (meropenem)
|
||||
```
|
||||
|
||||
| Pathogen | Amikacin | Gentamicin | Imipenem | Kanamycin | Meropenem | Tobramycin |
|
||||
@@ -344,15 +344,15 @@ out <- example_isolates %>%
|
||||
# calculate AMR using resistance(), over all aminoglycosides and polymyxins:
|
||||
summarise(across(c(aminoglycosides(), polymyxins()),
|
||||
resistance))
|
||||
#> ℹ For `aminoglycosides()` using columns GEN (gentamicin), TOB (tobramycin), AMK
|
||||
#> (amikacin), and KAN (kanamycin)
|
||||
#> ℹ For `polymyxins()` using column COL (colistin)
|
||||
#> ℹ For `aminoglycosides()` using columns 'GEN' (gentamicin), 'TOB'
|
||||
#> (tobramycin), 'AMK' (amikacin), and 'KAN' (kanamycin)
|
||||
#> ℹ For `polymyxins()` using column 'COL' (colistin)
|
||||
#> Warning: There was 1 warning in `summarise()`.
|
||||
#> ℹ In argument: `across(c(aminoglycosides(), polymyxins()), resistance)`.
|
||||
#> ℹ In group 3: `ward = "Outpatient"`.
|
||||
#> Caused by warning:
|
||||
#> ! Introducing NA: only 23 results available for KAN in group: ward = "Outpatient"
|
||||
#> (whilst `minimum = 30`).
|
||||
#> ! Introducing NA: only 23 results available for KAN in group: ward =
|
||||
#> "Outpatient" (`minimum` = 30).
|
||||
out
|
||||
#> # A tibble: 3 × 6
|
||||
#> ward GEN TOB AMK KAN COL
|
||||
|
||||
@@ -18,14 +18,14 @@ This is an overview of all the package-specific options you can set in the \code
|
||||
\item \code{AMR_custom_ab} \cr A file location to an RDS file, to use custom antimicrobial drugs with this package. This is explained in \code{\link[=add_custom_antimicrobials]{add_custom_antimicrobials()}}.
|
||||
\item \code{AMR_custom_mo} \cr A file location to an RDS file, to use custom microorganisms with this package. This is explained in \code{\link[=add_custom_microorganisms]{add_custom_microorganisms()}}.
|
||||
\item \code{AMR_eucastrules} \cr A \link{character} to set the default types of rules for \code{\link[=eucast_rules]{eucast_rules()}} function, must be one or more of: \code{"breakpoints"}, \code{"expert"}, \code{"other"}, \code{"custom"}, \code{"all"}, and defaults to \code{c("breakpoints", "expert")}.
|
||||
\item \code{AMR_guideline} \cr A \link{character} to set the default guideline used throughout the \code{AMR} package wherever a \code{guideline} argument is available. This option is used as the default in e.g. \code{\link[=as.sir]{as.sir()}}, \code{\link[=resistance]{resistance()}}, \code{\link[=susceptibility]{susceptibility()}}, \code{\link[=interpretive_rules]{interpretive_rules()}} and many plotting functions. \strong{While unset}, the AMR package uses the latest implemented EUCAST guideline (currently EUCAST 2026).
|
||||
\item \code{AMR_guideline} \cr A \link{character} to set the default guideline used throughout the \code{AMR} package wherever a \code{guideline} argument is available. This option is used as the default in e.g. \code{\link[=as.sir]{as.sir()}}, \code{\link[=resistance]{resistance()}}, \code{\link[=susceptibility]{susceptibility()}}, \code{\link[=interpretive_rules]{interpretive_rules()}} and many plotting functions. \strong{While unset}, the AMR package uses the latest implemented EUCAST guideline (currently EUCAST 2025).
|
||||
\itemize{
|
||||
\item For \code{\link[=as.sir]{as.sir()}}, this determines which clinical breakpoint guideline is used to interpret MIC values and disk diffusion diameters. It can be either the guideline name (e.g., \code{"CLSI"} or \code{"EUCAST"}) or the name including a year (e.g., \code{"CLSI 2019"}). Supported guidelines are EUCAST 2011 to 2026, and CLSI 2011 to 2026.
|
||||
\item For \code{\link[=as.sir]{as.sir()}}, this determines which clinical breakpoint guideline is used to interpret MIC values and disk diffusion diameters. It can be either the guideline name (e.g., \code{"CLSI"} or \code{"EUCAST"}) or the name including a year (e.g., \code{"CLSI 2019"}). Supported guidelines are EUCAST 2011 to 2025, and CLSI 2011 to 2025.
|
||||
\item For \code{\link[=resistance]{resistance()}} and \code{\link[=susceptibility]{susceptibility()}}, this setting determines how the \code{"I"} (Intermediate / Increased exposure) category is handled in calculations. Under CLSI, \code{"I"} is considered \emph{resistant} in susceptibility calculations; under EUCAST, \code{"I"} is considered \emph{susceptible} in susceptibility calculations. Explicitly setting this option ensures reproducible AMR proportion estimates.
|
||||
\item For \code{\link[=interpretive_rules]{interpretive_rules()}}, this determines which guideline-specific interpretive (expert) rules are applied to antimicrobial test results, either EUCAST or CLSI.
|
||||
\item For many plotting functions (e.g., for MIC or disk diffusion values), supplying \code{mo} and \code{ab} enables automatic SIR-based interpretative colouring. These colours are derived from \code{\link[=as.sir]{as.sir()}} in the background and therefore depend on the active \code{guideline} setting, which again uses EUCAST 2026 if not set explicitly.
|
||||
\item For many plotting functions (e.g., for MIC or disk diffusion values), supplying \code{mo} and \code{ab} enables automatic SIR-based interpretative colouring. These colours are derived from \code{\link[=as.sir]{as.sir()}} in the background and therefore depend on the active \code{guideline} setting, which again uses EUCAST 2025 if not set explicitly.
|
||||
}
|
||||
\item \code{AMR_guideline} \cr A \link{character} to set the default guideline for interpreting MIC values and disk diffusion diameters with \code{\link[=as.sir]{as.sir()}}. Can be only the guideline name (e.g., \code{"CLSI"}) or the name with a year (e.g. \code{"CLSI 2019"}). The default to the latest implemented EUCAST guideline, currently \code{"EUCAST 2026"}. Supported guideline are currently EUCAST (2011-2026) and CLSI (2011-2026).
|
||||
\item \code{AMR_guideline} \cr A \link{character} to set the default guideline for interpreting MIC values and disk diffusion diameters with \code{\link[=as.sir]{as.sir()}}. Can be only the guideline name (e.g., \code{"CLSI"}) or the name with a year (e.g. \code{"CLSI 2019"}). The default to the latest implemented EUCAST guideline, currently \code{"EUCAST 2025"}. Supported guideline are currently EUCAST (2011-2025) and CLSI (2011-2025).
|
||||
\item \code{AMR_ignore_pattern} \cr A \link[base:regex]{regular expression} to ignore (i.e., make \code{NA}) any match given in \code{\link[=as.mo]{as.mo()}} and all \code{\link[=mo_property]{mo_*}} functions.
|
||||
\item \code{AMR_include_PKPD} \cr A \link{logical} to use in \code{\link[=as.sir]{as.sir()}}, to indicate that PK/PD clinical breakpoints must be applied as a last resort - the default is \code{TRUE}.
|
||||
\item \code{AMR_substitute_missing_r_breakpoint} \cr A \link{logical} to use in \code{\link[=as.sir]{as.sir()}}, to indicate that missing R breakpoints must be substituted with \code{"R"} - the default is \code{FALSE}.
|
||||
|
||||
@@ -32,7 +32,7 @@ The \code{AMR} package is a peer-reviewed, \href{https://amr-for-r.org/#copyrigh
|
||||
|
||||
This work was published in the Journal of Statistical Software (Volume 104(3); \doi{10.18637/jss.v104.i03}) and formed the basis of two PhD theses (\doi{10.33612/diss.177417131} and \doi{10.33612/diss.192486375}).
|
||||
|
||||
After installing this package, R knows \href{https://amr-for-r.org/reference/microorganisms.html}{\strong{~79 000 distinct microbial species}} (updated June 2024) and all \href{https://amr-for-r.org/reference/antimicrobials.html}{\strong{~620 antimicrobial and antiviral drugs}} by name and code (including ATC, EARS-Net, ASIARS-Net, PubChem, LOINC and SNOMED CT), and knows all about valid SIR and MIC values. The integral clinical breakpoint guidelines from CLSI 2011-2026 and EUCAST 2011-2026 are included, even with epidemiological cut-off (ECOFF) values. It supports and can read any data format, including WHONET data. This package works on Windows, macOS and Linux with all versions of R since R-3.0 (April 2013). \strong{It was designed to work in any setting, including those with very limited resources}. It was created for both routine data analysis and academic research at the Faculty of Medical Sciences of the \href{https://www.rug.nl}{University of Groningen} and the \href{https://www.umcg.nl}{University Medical Center Groningen}.
|
||||
After installing this package, R knows \href{https://amr-for-r.org/reference/microorganisms.html}{\strong{~79 000 distinct microbial species}} (updated June 2024) and all \href{https://amr-for-r.org/reference/antimicrobials.html}{\strong{~620 antimicrobial and antiviral drugs}} by name and code (including ATC, EARS-Net, ASIARS-Net, PubChem, LOINC and SNOMED CT), and knows all about valid SIR and MIC values. The integral clinical breakpoint guidelines from CLSI 2011-2025 and EUCAST 2011-2025 are included, even with epidemiological cut-off (ECOFF) values. It supports and can read any data format, including WHONET data. This package works on Windows, macOS and Linux with all versions of R since R-3.0 (April 2013). \strong{It was designed to work in any setting, including those with very limited resources}. It was created for both routine data analysis and academic research at the Faculty of Medical Sciences of the \href{https://www.rug.nl}{University of Groningen} and the \href{https://www.umcg.nl}{University Medical Center Groningen}.
|
||||
|
||||
The \code{AMR} package is available in English, Arabic, Bengali, Chinese, Czech, Danish, Dutch, Finnish, French, German, Greek, Hindi, Indonesian, Italian, Japanese, Korean, Norwegian, Polish, Portuguese, Romanian, Russian, Spanish, Swahili, Swedish, Turkish, Ukrainian, Urdu, and Vietnamese. Antimicrobial drug (group) names and colloquial microorganism names are provided in these languages.
|
||||
}
|
||||
|
||||
@@ -50,13 +50,13 @@ Ordered \link{factor} with additional class \code{\link{mic}}, that in mathemati
|
||||
This transforms vectors to a new class \code{\link{mic}}, which treats the input as decimal numbers, while maintaining operators (such as ">=") and only allowing valid MIC values known to the field of (medical) microbiology.
|
||||
}
|
||||
\details{
|
||||
To interpret MIC values as SIR values, use \code{\link[=as.sir]{as.sir()}} on MIC values. It supports guidelines from EUCAST (2011-2026) and CLSI (2011-2026).
|
||||
To interpret MIC values as SIR values, use \code{\link[=as.sir]{as.sir()}} on MIC values. It supports guidelines from EUCAST (2011-2025) and CLSI (2011-2025).
|
||||
|
||||
This class for MIC values is a quite a special data type: formally it is an ordered \link{factor} with valid MIC values as \link{factor} levels (to make sure only valid MIC values are retained), but for any mathematical operation it acts as decimal numbers:
|
||||
|
||||
\if{html}{\out{<div class="sourceCode">}}\preformatted{x <- random_mic(10)
|
||||
x
|
||||
#> Class <mic>
|
||||
#> Class 'mic'
|
||||
#> [1] 16 1 8 8 64 >=128 0.0625 32 32 16
|
||||
|
||||
is.factor(x)
|
||||
@@ -72,7 +72,7 @@ median(x)
|
||||
This makes it possible to maintain operators that often come with MIC values, such ">=" and "<=", even when filtering using \link{numeric} values in data analysis, e.g.:
|
||||
|
||||
\if{html}{\out{<div class="sourceCode">}}\preformatted{x[x > 4]
|
||||
#> Class <mic>
|
||||
#> Class 'mic'
|
||||
#> [1] 16 8 8 64 >=128 32 32 16
|
||||
|
||||
df <- data.frame(x, hospital = "A")
|
||||
|
||||
@@ -16,11 +16,11 @@
|
||||
\source{
|
||||
For interpretations of minimum inhibitory concentration (MIC) values and disk diffusion diameters:
|
||||
\itemize{
|
||||
\item \strong{CLSI M39: Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data}, 2011-2026, \emph{Clinical and Laboratory Standards Institute} (CLSI). \url{https://clsi.org/standards/products/microbiology/documents/m39/}.
|
||||
\item \strong{CLSI M100: Performance Standard for Antimicrobial Susceptibility Testing}, 2011-2026, \emph{Clinical and Laboratory Standards Institute} (CLSI). \url{https://clsi.org/standards/products/microbiology/documents/m100/}.
|
||||
\item \strong{CLSI VET01: Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals}, 2019-2026, \emph{Clinical and Laboratory Standards Institute} (CLSI). \url{https://clsi.org/standards/products/veterinary-medicine/documents/vet01/}.
|
||||
\item \strong{EUCAST Breakpoint tables for interpretation of MICs and zone diameters}, 2011-2026, \emph{European Committee on Antimicrobial Susceptibility Testing} (EUCAST). \url{https://www.eucast.org/bacteria/clinical-breakpoints-and-interpretation/clinical-breakpoint-tables/}.
|
||||
\item \strong{WHONET} as a source for machine-reading the clinical breakpoints (\href{https://amr-for-r.org/reference/clinical_breakpoints.html#imported-from-whonet}{read more here}), 1989-2026, \emph{WHO Collaborating Centre for Surveillance of Antimicrobial Resistance}. \url{https://whonet.org/}.
|
||||
\item \strong{CLSI M39: Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data}, 2011-2025, \emph{Clinical and Laboratory Standards Institute} (CLSI). \url{https://clsi.org/standards/products/microbiology/documents/m39/}.
|
||||
\item \strong{CLSI M100: Performance Standard for Antimicrobial Susceptibility Testing}, 2011-2025, \emph{Clinical and Laboratory Standards Institute} (CLSI). \url{https://clsi.org/standards/products/microbiology/documents/m100/}.
|
||||
\item \strong{CLSI VET01: Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated From Animals}, 2019-2025, \emph{Clinical and Laboratory Standards Institute} (CLSI). \url{https://clsi.org/standards/products/veterinary-medicine/documents/vet01/}.
|
||||
\item \strong{EUCAST Breakpoint tables for interpretation of MICs and zone diameters}, 2011-2025, \emph{European Committee on Antimicrobial Susceptibility Testing} (EUCAST). \url{https://www.eucast.org/bacteria/clinical-breakpoints-and-interpretation/clinical-breakpoint-tables/}.
|
||||
\item \strong{WHONET} as a source for machine-reading the clinical breakpoints (\href{https://amr-for-r.org/reference/clinical_breakpoints.html#imported-from-whonet}{read more here}), 1989-2025, \emph{WHO Collaborating Centre for Surveillance of Antimicrobial Resistance}. \url{https://whonet.org/}.
|
||||
}
|
||||
}
|
||||
\usage{
|
||||
@@ -94,7 +94,7 @@ Otherwise: arguments passed on to methods.}
|
||||
|
||||
\item{ab}{A vector (or column name) with \link{character}s that can be coerced to a valid antimicrobial drug code with \code{\link[=as.ab]{as.ab()}}.}
|
||||
|
||||
\item{guideline}{A guideline name (or column name) to use for SIR interpretation. Defaults to EUCAST 2026 (the latest implemented EUCAST guideline in the \link{clinical_breakpoints} data set), but can be set with the package option \code{\link[=AMR-options]{AMR_guideline}}. Currently supports EUCAST (2011-2026) and CLSI (2011-2026), see \emph{Details}. Using a column name allows for straightforward interpretation of historical data, which must be analysed in the context of, for example, different years.}
|
||||
\item{guideline}{A guideline name (or column name) to use for SIR interpretation. Defaults to EUCAST 2025 (the latest implemented EUCAST guideline in the \link{clinical_breakpoints} data set), but can be set with the package option \code{\link[=AMR-options]{AMR_guideline}}. Currently supports EUCAST (2011-2025) and CLSI (2011-2025), see \emph{Details}. Using a column name allows for straightforward interpretation of historical data, which must be analysed in the context of, for example, different years.}
|
||||
|
||||
\item{uti}{(Urinary Tract Infection) a vector (or column name) with \link{logical}s (\code{TRUE} or \code{FALSE}) to specify whether a UTI specific interpretation from the guideline should be chosen. For using \code{\link[=as.sir]{as.sir()}} on a \link{data.frame}, this can also be a column containing \link{logical}s or when left blank, the data set will be searched for a column 'specimen', and rows within this column containing 'urin' (such as 'urine', 'urina') will be regarded isolates from a UTI. See \emph{Examples}.}
|
||||
|
||||
@@ -162,7 +162,7 @@ Ordered \link{factor} with new class \code{sir}
|
||||
\description{
|
||||
Clean up existing SIR values, or interpret minimum inhibitory concentration (MIC) values and disk diffusion diameters according to EUCAST or CLSI. \code{\link[=as.sir]{as.sir()}} transforms the input to a new class \code{\link{sir}}, which is an ordered \link{factor} containing the levels \code{S}, \code{SDD}, \code{I}, \code{R}, \code{NI}.
|
||||
|
||||
Breakpoints are currently implemented from EUCAST 2011-2026 and CLSI 2011-2026, see \emph{Details}. All breakpoints used for interpretation are available in our \link{clinical_breakpoints} data set.
|
||||
Breakpoints are currently implemented from EUCAST 2011-2025 and CLSI 2011-2025, see \emph{Details}. All breakpoints used for interpretation are available in our \link{clinical_breakpoints} data set.
|
||||
}
|
||||
\details{
|
||||
\emph{Note: The clinical breakpoints in this package were validated through, and imported from, \href{https://whonet.org}{WHONET}. The public use of this \code{AMR} package has been endorsed by both CLSI and EUCAST. See \link{clinical_breakpoints} for more information.}
|
||||
@@ -215,12 +215,12 @@ as.sir(your_data, ..., parallel = TRUE)
|
||||
|
||||
For interpreting MIC values as well as disk diffusion diameters, currently implemented guidelines are:
|
||||
\itemize{
|
||||
\item For \strong{clinical microbiology}: EUCAST 2011-2026 and CLSI 2011-2026;
|
||||
\item For \strong{veterinary microbiology}: EUCAST 2021-2026 and CLSI 2019-2026;
|
||||
\item For \strong{ECOFFs} (Epidemiological Cut-off Values): EUCAST 2020-2026 and CLSI 2022-2026.
|
||||
\item For \strong{clinical microbiology}: EUCAST 2011-2025 and CLSI 2011-2025;
|
||||
\item For \strong{veterinary microbiology}: EUCAST 2021-2025 and CLSI 2019-2025;
|
||||
\item For \strong{ECOFFs} (Epidemiological Cut-off Values): EUCAST 2020-2025 and CLSI 2022-2025.
|
||||
}
|
||||
|
||||
The \code{guideline} argument must be set to e.g., \code{"EUCAST 2026"} or \code{"CLSI 2026"}. By simply using \code{"EUCAST"} (the default) or \code{"CLSI"} as input, the latest included version of that guideline will automatically be selected. Importantly, using a column name of your data instead, allows for straightforward interpretation of historical data that must be analysed in the context of, for example, different years.
|
||||
The \code{guideline} argument must be set to e.g., \code{"EUCAST 2025"} or \code{"CLSI 2025"}. By simply using \code{"EUCAST"} (the default) or \code{"CLSI"} as input, the latest included version of that guideline will automatically be selected. Importantly, using a column name of your data instead, allows for straightforward interpretation of historical data that must be analysed in the context of, for example, different years.
|
||||
|
||||
You can set your own data set using the \code{reference_data} argument. The \code{guideline} argument will then be ignored.
|
||||
|
||||
|
||||
@@ -5,7 +5,7 @@
|
||||
\alias{clinical_breakpoints}
|
||||
\title{Data Set with Clinical Breakpoints for SIR Interpretation}
|
||||
\format{
|
||||
A \link[tibble:tibble]{tibble} with 45 797 observations and 14 variables:
|
||||
A \link[tibble:tibble]{tibble} with 40 217 observations and 14 variables:
|
||||
\itemize{
|
||||
\item \code{guideline}\cr Name of the guideline
|
||||
\item \code{type}\cr Breakpoint type, either "ECOFF", "animal", or "human"
|
||||
@@ -20,7 +20,7 @@ A \link[tibble:tibble]{tibble} with 45 797 observations and 14 variables:
|
||||
\item \code{breakpoint_S}\cr Lowest MIC value or highest number of millimetres that leads to "S"
|
||||
\item \code{breakpoint_R}\cr Highest MIC value or lowest number of millimetres that leads to "R", can be \code{NA}
|
||||
\item \code{uti}\cr A \link{logical} value (\code{TRUE}/\code{FALSE}) to indicate whether the rule applies to a urinary tract infection (UTI)
|
||||
\item \code{is_SDD}\cr A \link{logical} value (\code{TRUE}/\code{FALSE}) to indicate whether the intermediate range between "S" and "R" should be interpreted as "SDD", instead of "I". This currently applies to 72 breakpoints.
|
||||
\item \code{is_SDD}\cr A \link{logical} value (\code{TRUE}/\code{FALSE}) to indicate whether the intermediate range between "S" and "R" should be interpreted as "SDD", instead of "I". This currently applies to 48 breakpoints.
|
||||
}
|
||||
}
|
||||
\usage{
|
||||
@@ -31,9 +31,9 @@ Data set containing clinical breakpoints to interpret MIC and disk diffusion to
|
||||
|
||||
These breakpoints are currently implemented:
|
||||
\itemize{
|
||||
\item For \strong{clinical microbiology}: EUCAST 2011-2026 and CLSI 2011-2026;
|
||||
\item For \strong{veterinary microbiology}: EUCAST 2021-2026 and CLSI 2019-2026;
|
||||
\item For \strong{ECOFFs} (Epidemiological Cut-off Values): EUCAST 2020-2026 and CLSI 2022-2026.
|
||||
\item For \strong{clinical microbiology}: EUCAST 2011-2025 and CLSI 2011-2025;
|
||||
\item For \strong{veterinary microbiology}: EUCAST 2021-2025 and CLSI 2019-2025;
|
||||
\item For \strong{ECOFFs} (Epidemiological Cut-off Values): EUCAST 2020-2025 and CLSI 2022-2025.
|
||||
}
|
||||
|
||||
Use \code{\link[=as.sir]{as.sir()}} to transform MICs or disks measurements to SIR values.
|
||||
|
||||
@@ -3,9 +3,9 @@
|
||||
\docType{data}
|
||||
\name{microorganisms.codes}
|
||||
\alias{microorganisms.codes}
|
||||
\title{Data Set with 6 050 Common Microorganism Codes}
|
||||
\title{Data Set with 6 036 Common Microorganism Codes}
|
||||
\format{
|
||||
A \link[tibble:tibble]{tibble} with 6 050 observations and 2 variables:
|
||||
A \link[tibble:tibble]{tibble} with 6 036 observations and 2 variables:
|
||||
\itemize{
|
||||
\item \code{code}\cr Commonly used code of a microorganism. \emph{\strong{This is a unique identifier.}}
|
||||
\item \code{mo}\cr ID of the microorganism in the \link{microorganisms} data set
|
||||
|
||||
@@ -58,7 +58,7 @@ It has now created a file \code{"~/mo_source.rds"} with the contents of our Exce
|
||||
And now we can use it in our functions:
|
||||
|
||||
\if{html}{\out{<div class="sourceCode">}}\preformatted{as.mo("lab_mo_ecoli")
|
||||
#> Class <mo>
|
||||
#> Class 'mo'
|
||||
#> [1] B_ESCHR_COLI
|
||||
|
||||
mo_genus("lab_mo_kpneumoniae")
|
||||
@@ -68,7 +68,7 @@ mo_genus("lab_mo_kpneumoniae")
|
||||
as.mo(c("Escherichia coli", "E. coli", "lab_mo_ecoli"))
|
||||
#> NOTE: Translation to one microorganism was guessed with uncertainty.
|
||||
#> Use mo_uncertainties() to review it.
|
||||
#> Class <mo>
|
||||
#> Class 'mo'
|
||||
#> [1] B_ESCHR_COLI B_ESCHR_COLI B_ESCHR_COLI
|
||||
}\if{html}{\out{</div>}}
|
||||
|
||||
@@ -89,7 +89,7 @@ If we edit the Excel file by, let's say, adding row 4 like this:
|
||||
#> NOTE: Updated mo_source file '/Users/me/mo_source.rds' (0.3 kB) from
|
||||
#> '/Users/me/Documents/ourcodes.xlsx' (9 kB), columns
|
||||
#> "Organisation XYZ" and "mo"
|
||||
#> Class <mo>
|
||||
#> Class 'mo'
|
||||
#> [1] B_ESCHR_COLI
|
||||
|
||||
mo_genus("lab_Staph_aureus")
|
||||
|
||||
@@ -201,7 +201,7 @@ This package contains more functions that extend the \code{ggplot2} package, to
|
||||
|
||||
The interpretation of "I" will be named "Increased exposure" for all EUCAST guidelines since 2019, and will be named "Intermediate" in all other cases.
|
||||
|
||||
For interpreting MIC values as well as disk diffusion diameters, the default guideline is EUCAST 2026, unless the package option \code{\link[=AMR-options]{AMR_guideline}} is set. See \code{\link[=as.sir]{as.sir()}} for more information.
|
||||
For interpreting MIC values as well as disk diffusion diameters, the default guideline is EUCAST 2025, unless the package option \code{\link[=AMR-options]{AMR_guideline}} is set. See \code{\link[=as.sir]{as.sir()}} for more information.
|
||||
}
|
||||
}
|
||||
\examples{
|
||||
|
||||
@@ -219,6 +219,7 @@ test_that("test-eucast_rules.R", {
|
||||
expect_inherits(eucast_dosage(c("tobra", "genta", "cipro")), "data.frame")
|
||||
|
||||
|
||||
|
||||
x <- custom_eucast_rules(
|
||||
AMC == "R" & genus == "Klebsiella" ~ aminopenicillins == "R",
|
||||
AMC == "I" & genus == "Klebsiella" ~ aminopenicillins == "I",
|
||||
|
||||
@@ -272,6 +272,8 @@ test_that("test-mo.R", {
|
||||
)
|
||||
|
||||
x <- as.mo("Sta. aur")
|
||||
# many hits
|
||||
expect_output(print(mo_uncertainties()))
|
||||
|
||||
# no viruses
|
||||
expect_equal(suppressWarnings(as.mo("Virus")), as.mo("UNKNOWN"))
|
||||
|
||||
@@ -120,7 +120,7 @@ test_that("test-sir.R", {
|
||||
# allow for guideline length > 1
|
||||
expect_equal(
|
||||
AMR:::get_guideline(c("CLSI", "CLSI", "CLSI2023", "EUCAST", "EUCAST2020"), AMR::clinical_breakpoints),
|
||||
c("CLSI 2026", "CLSI 2026", "CLSI 2023", "EUCAST 2026", "EUCAST 2020")
|
||||
c("CLSI 2025", "CLSI 2025", "CLSI 2023", "EUCAST 2025", "EUCAST 2020")
|
||||
)
|
||||
|
||||
# these are used in the script
|
||||
|
||||
@@ -36,7 +36,6 @@ test_that("test-zzz.R", {
|
||||
# functions used by import_fn()
|
||||
import_functions <- c(
|
||||
"%chin%" = "data.table",
|
||||
"ansi_has_hyperlink_support" = "cli",
|
||||
"anti_join" = "dplyr",
|
||||
"as.data.table" = "data.table",
|
||||
"as_tibble" = "tibble",
|
||||
@@ -80,12 +79,6 @@ test_that("test-zzz.R", {
|
||||
"freq.default" = "cleaner",
|
||||
"percentage" = "cleaner",
|
||||
# cli
|
||||
"ansi_has_hyperlink_support" = "cli",
|
||||
"cli_abort" = "cli",
|
||||
"cli_inform" = "cli",
|
||||
"cli_warn" = "cli",
|
||||
"code_highlight" = "cli",
|
||||
"format_inline" = "cli",
|
||||
"symbol" = "cli",
|
||||
# curl
|
||||
"has_internet" = "curl",
|
||||
@@ -131,8 +124,6 @@ test_that("test-zzz.R", {
|
||||
"availableCores" = "parallelly",
|
||||
# pillar
|
||||
"pillar_shaft" = "pillar",
|
||||
"style_na" = "pillar",
|
||||
"style_subtle" = "pillar",
|
||||
"tbl_format_footer" = "pillar",
|
||||
"tbl_sum" = "pillar",
|
||||
"type_sum" = "pillar",
|
||||
@@ -170,9 +161,7 @@ test_that("test-zzz.R", {
|
||||
"vec_math" = "vctrs",
|
||||
"vec_ptype2" = "vctrs",
|
||||
"vec_ptype_abbr" = "vctrs",
|
||||
"vec_ptype_full" = "vctrs",
|
||||
# usethis
|
||||
"use_course" = "usethis"
|
||||
"vec_ptype_full" = "vctrs"
|
||||
)
|
||||
|
||||
import_functions <- c(import_functions, call_functions)
|
||||
|
||||
Reference in New Issue
Block a user