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437 lines
18 KiB
Markdown
437 lines
18 KiB
Markdown
# Get Properties of an Antibiotic
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Use these functions to return a specific property of an antibiotic from
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the [antimicrobials](https://amr-for-r.org/reference/antimicrobials.md)
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data set. All input values will be evaluated internally with
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[`as.ab()`](https://amr-for-r.org/reference/as.ab.md).
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## Usage
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``` r
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ab_name(x, language = get_AMR_locale(), tolower = FALSE, ...)
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ab_cid(x, ...)
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ab_synonyms(x, ...)
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ab_tradenames(x, ...)
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ab_group(x, language = get_AMR_locale(), ...)
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ab_atc(x, only_first = FALSE, ...)
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ab_atc_group1(x, language = get_AMR_locale(), ...)
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ab_atc_group2(x, language = get_AMR_locale(), ...)
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ab_loinc(x, ...)
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ab_ddd(x, administration = "oral", ...)
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ab_ddd_units(x, administration = "oral", ...)
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ab_info(x, language = get_AMR_locale(), ...)
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ab_url(x, open = FALSE, ...)
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ab_property(x, property = "name", language = get_AMR_locale(), ...)
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set_ab_names(data, ..., property = "name", language = get_AMR_locale(),
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snake_case = NULL)
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```
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## Arguments
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- x:
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Any (vector of) text that can be coerced to a valid antibiotic drug
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code with [`as.ab()`](https://amr-for-r.org/reference/as.ab.md).
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- language:
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Language of the returned text - the default is the current system
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language (see
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[`get_AMR_locale()`](https://amr-for-r.org/reference/translate.md))
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and can also be set with the package option
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[`AMR_locale`](https://amr-for-r.org/reference/AMR-options.md). Use
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`language = NULL` or `language = ""` to prevent translation.
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- tolower:
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A [logical](https://rdrr.io/r/base/logical.html) to indicate whether
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the first [character](https://rdrr.io/r/base/character.html) of every
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output should be transformed to a lower case
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[character](https://rdrr.io/r/base/character.html). This will lead to
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e.g. "polymyxin B" and not "polymyxin b".
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- ...:
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In case of `set_ab_names()` and `data` is a
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[data.frame](https://rdrr.io/r/base/data.frame.html): columns to
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select (supports tidy selection such as `column1:column4`), otherwise
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other arguments passed on to
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[`as.ab()`](https://amr-for-r.org/reference/as.ab.md).
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- only_first:
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A [logical](https://rdrr.io/r/base/logical.html) to indicate whether
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only the first ATC code must be returned, with giving preference to
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J0-codes (i.e., the antimicrobial drug group).
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- administration:
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Way of administration, either `"oral"` or `"iv"`.
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- open:
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Browse the URL using
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[`utils::browseURL()`](https://rdrr.io/r/utils/browseURL.html).
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- property:
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One of the column names of one of the
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[antimicrobials](https://amr-for-r.org/reference/antimicrobials.md)
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data set: `vector_or(colnames(antimicrobials), sort = FALSE)`.
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- data:
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A [data.frame](https://rdrr.io/r/base/data.frame.html) of which the
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columns need to be renamed, or a
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[character](https://rdrr.io/r/base/character.html) vector of column
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names.
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- snake_case:
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A [logical](https://rdrr.io/r/base/logical.html) to indicate whether
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the names should be in so-called [snake
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case](https://en.wikipedia.org/wiki/Snake_case): in lower case and all
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spaces/slashes replaced with an underscore (`_`).
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## Value
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- An [integer](https://rdrr.io/r/base/integer.html) in case of
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`ab_cid()`
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- A named [list](https://rdrr.io/r/base/list.html) in case of
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`ab_info()` and multiple `ab_atc()`/`ab_synonyms()`/`ab_tradenames()`
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- A [double](https://rdrr.io/r/base/double.html) in case of `ab_ddd()`
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- A [data.frame](https://rdrr.io/r/base/data.frame.html) in case of
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`set_ab_names()`
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- A [character](https://rdrr.io/r/base/character.html) in all other
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cases
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## Details
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All output [will be
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translated](https://amr-for-r.org/reference/translate.md) where
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possible.
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The function `ab_url()` will return the direct URL to the official WHO
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website. A warning will be returned if the required ATC code is not
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available.
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The function `set_ab_names()` is a special column renaming function for
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[data.frame](https://rdrr.io/r/base/data.frame.html)s. It renames
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columns names that resemble antimicrobial drugs. It always makes sure
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that the new column names are unique. If `property = "atc"` is set,
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preference is given to ATC codes from the J-group.
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## Source
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World Health Organization (WHO) Collaborating Centre for Drug Statistics
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Methodology: <https://atcddd.fhi.no/atc_ddd_index/>
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European Commission Public Health PHARMACEUTICALS - COMMUNITY REGISTER:
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<https://ec.europa.eu/health/documents/community-register/html/reg_hum_atc.htm>
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## Download Our Reference Data
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All reference data sets in the AMR package - including information on
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microorganisms, antimicrobials, and clinical breakpoints - are freely
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available for download in multiple formats: R, MS Excel, Apache Feather,
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Apache Parquet, SPSS, and Stata.
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For maximum compatibility, we also provide machine-readable,
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tab-separated plain text files suitable for use in any software,
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including laboratory information systems.
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Visit [our website for direct download
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links](https://amr-for-r.org/articles/datasets.html), or explore the
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actual files in [our GitHub
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repository](https://github.com/msberends/AMR/tree/main/data-raw/datasets).
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## See also
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[antimicrobials](https://amr-for-r.org/reference/antimicrobials.md)
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## Examples
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``` r
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# all properties:
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ab_name("AMX")
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#> [1] "Amoxicillin"
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ab_atc("AMX")
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#> [1] "J01CA04" "QG51AA03" "QJ01CA04"
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ab_cid("AMX")
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#> [1] 33613
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ab_synonyms("AMX")
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#> [1] "acuotricina" "alfamox" "alfida" "amitron"
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#> [5] "amoclen" "amodex" "amoksicillin" "amolin"
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#> [9] "amopen" "amopenixin" "amophar" "amoran"
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#> [13] "amoxi" "amoxicaps" "amoxicilina" "amoxicilline"
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#> [17] "amoxicillinum" "amoxidal" "amoxiden" "amoxil"
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#> [21] "amoxillat" "amoxina" "amoxine" "amoxipen"
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#> [25] "amoxivet" "amoxycillin" "amoxycillinsalt" "amoxyke"
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#> [29] "anemolin" "aspenil" "atoksilin" "bristamox"
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#> [33] "cemoxin" "ciblor" "clamoxyl" "damoxy"
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#> [37] "danoxillin" "delacillin" "demoksil" "dispermox"
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#> [41] "efpenix" "eupen" "flemoxin" "flemoxine"
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#> [45] "galenamox" "gramidil" "hiconcil" "himinomax"
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#> [49] "histocillin" "ibiamox" "imacillin" "izoltil"
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#> [53] "kentrocyllin" "lamoxy" "largopen" "larotid"
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#> [57] "matasedrin" "metifarma" "moksilin" "moxacin"
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#> [61] "moxal" "moxaline" "moxatag" "neotetranase"
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#> [65] "novabritine" "ospamox" "pacetocin" "pamocil"
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#> [69] "paradroxil" "pasetocin" "penamox" "piramox"
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#> [73] "promoxil" "quimiopen" "remoxil" "riotapen"
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#> [77] "robamox" "sawacillin" "siganopen" "simplamox"
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#> [81] "sintopen" "sumox" "topramoxin" "trifamox"
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#> [85] "trimox" "unicillin" "utimox" "velamox"
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#> [89] "vetramox" "wymox" "zamocillin" "zamocilline"
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#> [93] "zimox"
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ab_tradenames("AMX")
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#> [1] "acuotricina" "alfamox" "alfida" "amitron"
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#> [5] "amoclen" "amodex" "amoksicillin" "amolin"
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#> [9] "amopen" "amopenixin" "amophar" "amoran"
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#> [13] "amoxi" "amoxicaps" "amoxicilina" "amoxicilline"
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#> [17] "amoxicillinum" "amoxidal" "amoxiden" "amoxil"
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#> [21] "amoxillat" "amoxina" "amoxine" "amoxipen"
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#> [25] "amoxivet" "amoxycillin" "amoxycillinsalt" "amoxyke"
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#> [29] "anemolin" "aspenil" "atoksilin" "bristamox"
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#> [33] "cemoxin" "ciblor" "clamoxyl" "damoxy"
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#> [37] "danoxillin" "delacillin" "demoksil" "dispermox"
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#> [41] "efpenix" "eupen" "flemoxin" "flemoxine"
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#> [45] "galenamox" "gramidil" "hiconcil" "himinomax"
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#> [49] "histocillin" "ibiamox" "imacillin" "izoltil"
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#> [53] "kentrocyllin" "lamoxy" "largopen" "larotid"
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#> [57] "matasedrin" "metifarma" "moksilin" "moxacin"
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#> [61] "moxal" "moxaline" "moxatag" "neotetranase"
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#> [65] "novabritine" "ospamox" "pacetocin" "pamocil"
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#> [69] "paradroxil" "pasetocin" "penamox" "piramox"
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#> [73] "promoxil" "quimiopen" "remoxil" "riotapen"
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#> [77] "robamox" "sawacillin" "siganopen" "simplamox"
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#> [81] "sintopen" "sumox" "topramoxin" "trifamox"
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#> [85] "trimox" "unicillin" "utimox" "velamox"
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#> [89] "vetramox" "wymox" "zamocillin" "zamocilline"
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#> [93] "zimox"
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ab_group("AMX")
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#> [1] "Beta-lactams/penicillins"
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ab_atc_group1("AMX")
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#> [1] "Beta-lactam antibacterials, penicillins"
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ab_atc_group2("AMX")
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#> [1] "Penicillins with extended spectrum"
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ab_url("AMX")
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#> Amoxicillin
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#> "https://atcddd.fhi.no/atc_ddd_index//?code=J01CA04&showdescription=no"
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# smart lowercase transformation
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ab_name(x = c("AMC", "PLB"))
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#> [1] "Amoxicillin/clavulanic acid" "Polymyxin B"
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ab_name(x = c("AMC", "PLB"), tolower = TRUE)
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#> [1] "amoxicillin/clavulanic acid" "polymyxin B"
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# defined daily doses (DDD)
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ab_ddd("AMX", "oral")
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#> [1] 1.5
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ab_ddd_units("AMX", "oral")
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#> [1] "g"
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ab_ddd("AMX", "iv")
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#> [1] 3
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ab_ddd_units("AMX", "iv")
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#> [1] "g"
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ab_info("AMX") # all properties as a list
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#> $ab
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#> [1] "AMX"
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#>
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#> $cid
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#> [1] 33613
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#>
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#> $name
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#> [1] "Amoxicillin"
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#>
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#> $group
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#> [1] "Beta-lactams/penicillins"
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#>
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#> $atc
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#> [1] "J01CA04" "QG51AA03" "QJ01CA04"
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#>
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#> $atc_group1
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#> [1] "Beta-lactam antibacterials, penicillins"
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#>
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#> $atc_group2
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#> [1] "Penicillins with extended spectrum"
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#>
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#> $tradenames
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#> [1] "acuotricina" "alfamox" "alfida" "amitron"
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#> [5] "amoclen" "amodex" "amoksicillin" "amolin"
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#> [9] "amopen" "amopenixin" "amophar" "amoran"
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#> [13] "amoxi" "amoxicaps" "amoxicilina" "amoxicilline"
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#> [17] "amoxicillinum" "amoxidal" "amoxiden" "amoxil"
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#> [21] "amoxillat" "amoxina" "amoxine" "amoxipen"
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#> [25] "amoxivet" "amoxycillin" "amoxycillinsalt" "amoxyke"
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#> [29] "anemolin" "aspenil" "atoksilin" "bristamox"
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#> [33] "cemoxin" "ciblor" "clamoxyl" "damoxy"
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#> [37] "danoxillin" "delacillin" "demoksil" "dispermox"
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#> [41] "efpenix" "eupen" "flemoxin" "flemoxine"
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#> [45] "galenamox" "gramidil" "hiconcil" "himinomax"
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#> [49] "histocillin" "ibiamox" "imacillin" "izoltil"
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#> [53] "kentrocyllin" "lamoxy" "largopen" "larotid"
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#> [57] "matasedrin" "metifarma" "moksilin" "moxacin"
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#> [61] "moxal" "moxaline" "moxatag" "neotetranase"
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#> [65] "novabritine" "ospamox" "pacetocin" "pamocil"
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#> [69] "paradroxil" "pasetocin" "penamox" "piramox"
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#> [73] "promoxil" "quimiopen" "remoxil" "riotapen"
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#> [77] "robamox" "sawacillin" "siganopen" "simplamox"
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#> [81] "sintopen" "sumox" "topramoxin" "trifamox"
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#> [85] "trimox" "unicillin" "utimox" "velamox"
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#> [89] "vetramox" "wymox" "zamocillin" "zamocilline"
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#> [93] "zimox"
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#>
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#> $loinc
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#> [1] "101498-4" "15-8" "16-6" "16365-9" "17-4" "18-2"
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#> [7] "18861-5" "18862-3" "19-0" "20-8" "21-6" "22-4"
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#> [13] "25274-2" "25310-4" "3344-9" "55614-2" "55615-9" "55616-7"
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#> [19] "6976-5" "6977-3" "80133-2"
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#>
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#> $ddd
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#> $ddd$oral
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#> $ddd$oral$amount
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#> [1] 1.5
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#>
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#> $ddd$oral$units
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#> [1] "g"
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#>
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#>
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#> $ddd$iv
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#> $ddd$iv$amount
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#> [1] 3
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#>
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#> $ddd$iv$units
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#> [1] "g"
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#>
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#>
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#>
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# all ab_* functions use as.ab() internally, so you can go from 'any' to 'any':
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ab_atc("AMP")
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#> [1] "J01CA01" "QJ01CA01" "QJ51CA01" "QS01AA19" "S01AA19"
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ab_group("J01CA01")
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#> [1] "Beta-lactams/penicillins"
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ab_loinc("ampicillin")
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#> [1] "101477-8" "101478-6" "18864-9" "18865-6" "20374-5" "21066-6"
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#> [7] "23618-2" "27-3" "28-1" "29-9" "30-7" "31-5"
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#> [13] "32-3" "33-1" "3355-5" "33562-0" "33919-2" "34-9"
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#> [19] "43883-8" "43884-6" "6979-9" "6980-7" "87604-5"
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ab_name("21066-6")
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#> [1] "Ampicillin"
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ab_name(6249)
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#> [1] "Ampicillin"
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ab_name("J01CA01")
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#> [1] "Ampicillin"
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# spelling from different languages and dyslexia are no problem
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ab_atc("ceftriaxon")
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#> [1] "J01DD04" "QJ01DD04"
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ab_atc("cephtriaxone")
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#> [1] "J01DD04" "QJ01DD04"
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ab_atc("cephthriaxone")
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#> [1] "J01DD04" "QJ01DD04"
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ab_atc("seephthriaaksone")
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#> [1] "J01DD04" "QJ01DD04"
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# use set_ab_names() for renaming columns
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colnames(example_isolates)
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#> [1] "date" "patient" "age" "gender" "ward" "mo" "PEN"
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#> [8] "OXA" "FLC" "AMX" "AMC" "AMP" "TZP" "CZO"
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#> [15] "FEP" "CXM" "FOX" "CTX" "CAZ" "CRO" "GEN"
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#> [22] "TOB" "AMK" "KAN" "TMP" "SXT" "NIT" "FOS"
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#> [29] "LNZ" "CIP" "MFX" "VAN" "TEC" "TCY" "TGC"
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#> [36] "DOX" "ERY" "CLI" "AZM" "IPM" "MEM" "MTR"
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#> [43] "CHL" "COL" "MUP" "RIF"
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colnames(set_ab_names(example_isolates))
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#> [1] "date" "patient"
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#> [3] "age" "gender"
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#> [5] "ward" "mo"
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#> [7] "benzylpenicillin" "oxacillin"
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#> [9] "flucloxacillin" "amoxicillin"
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#> [11] "amoxicillin_clavulanic_acid" "ampicillin"
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#> [13] "piperacillin_tazobactam" "cefazolin"
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#> [15] "cefepime" "cefuroxime"
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#> [17] "cefoxitin" "cefotaxime"
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#> [19] "ceftazidime" "ceftriaxone"
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#> [21] "gentamicin" "tobramycin"
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#> [23] "amikacin" "kanamycin"
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#> [25] "trimethoprim" "trimethoprim_sulfamethoxazole"
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#> [27] "nitrofurantoin" "fosfomycin"
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#> [29] "linezolid" "ciprofloxacin"
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#> [31] "moxifloxacin" "vancomycin"
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#> [33] "teicoplanin" "tetracycline"
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#> [35] "tigecycline" "doxycycline"
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#> [37] "erythromycin" "clindamycin"
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#> [39] "azithromycin" "imipenem"
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#> [41] "meropenem" "metronidazole"
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#> [43] "chloramphenicol" "colistin"
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#> [45] "mupirocin" "rifampicin"
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colnames(set_ab_names(example_isolates, NIT:VAN))
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#> [1] "date" "patient" "age" "gender"
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|
#> [5] "ward" "mo" "PEN" "OXA"
|
|
#> [9] "FLC" "AMX" "AMC" "AMP"
|
|
#> [13] "TZP" "CZO" "FEP" "CXM"
|
|
#> [17] "FOX" "CTX" "CAZ" "CRO"
|
|
#> [21] "GEN" "TOB" "AMK" "KAN"
|
|
#> [25] "TMP" "SXT" "nitrofurantoin" "fosfomycin"
|
|
#> [29] "linezolid" "ciprofloxacin" "moxifloxacin" "vancomycin"
|
|
#> [33] "TEC" "TCY" "TGC" "DOX"
|
|
#> [37] "ERY" "CLI" "AZM" "IPM"
|
|
#> [41] "MEM" "MTR" "CHL" "COL"
|
|
#> [45] "MUP" "RIF"
|
|
# \donttest{
|
|
if (require("dplyr")) {
|
|
example_isolates %>%
|
|
set_ab_names()
|
|
|
|
# this does the same:
|
|
example_isolates %>%
|
|
rename_with(set_ab_names)
|
|
|
|
# set_ab_names() works with any AB property:
|
|
example_isolates %>%
|
|
set_ab_names(property = "atc")
|
|
|
|
example_isolates %>%
|
|
set_ab_names(where(is.sir)) %>%
|
|
colnames()
|
|
|
|
example_isolates %>%
|
|
set_ab_names(NIT:VAN) %>%
|
|
colnames()
|
|
}
|
|
#> [1] "date" "patient" "age" "gender"
|
|
#> [5] "ward" "mo" "PEN" "OXA"
|
|
#> [9] "FLC" "AMX" "AMC" "AMP"
|
|
#> [13] "TZP" "CZO" "FEP" "CXM"
|
|
#> [17] "FOX" "CTX" "CAZ" "CRO"
|
|
#> [21] "GEN" "TOB" "AMK" "KAN"
|
|
#> [25] "TMP" "SXT" "nitrofurantoin" "fosfomycin"
|
|
#> [29] "linezolid" "ciprofloxacin" "moxifloxacin" "vancomycin"
|
|
#> [33] "TEC" "TCY" "TGC" "DOX"
|
|
#> [37] "ERY" "CLI" "AZM" "IPM"
|
|
#> [41] "MEM" "MTR" "CHL" "COL"
|
|
#> [45] "MUP" "RIF"
|
|
# }
|
|
```
|