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1guidelineversiontypehostmethodsitemorank_indexabref_tbldisk_dosebreakpoint_Sbreakpoint_Rutiis_SDDis_screeningnotesheet
2EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAmpicillinEnterobacteralesNA88FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
3EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAmpicillinEnterobacterales10 mcg1414FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
4EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAmpicillin-sulbactamEnterobacteralesNA88FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [2] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
5EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAmpicillin-sulbactamEnterobacterales10/10 mcg1414FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [2] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
6EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAmoxicillinEnterobacteralesNA88FALSEFALSEFALSE[1] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [C] Susceptibility inferred from ampicillin.Enterobacterales
7EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAmoxicillinEnterobacterales/ mcgNoteNoteFALSEFALSEFALSE[1] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [C] Susceptibility inferred from ampicillin.Enterobacterales
8EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAmoxicillin-clavulanic acidEnterobacteralesNA88FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
9EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAmoxicillin-clavulanic acidEnterobacterales20/10 mcg1919FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
10EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAmoxicillin-clavulanic acid (uncomplicated UTI only)EnterobacteralesNA3232FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
11EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAmoxicillin-clavulanic acid (uncomplicated UTI only)Enterobacterales20/10 mcg1616FALSEFALSEFALSE[1/A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [B] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
12EUCAST 20199.0humanhumanMICNAEnterobacteralesNAPiperacillinEnterobacteralesNA816FALSEFALSEFALSENAEnterobacterales
13EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAPiperacillinEnterobacterales30 mcg2017FALSEFALSEFALSENAEnterobacterales
14EUCAST 20199.0humanhumanMICNAEnterobacteralesNAPiperacillin-tazobactamEnterobacteralesNA816FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
15EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAPiperacillin-tazobactamEnterobacterales30/6 mcg2017FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
16EUCAST 20199.0humanhumanMICNAEnterobacteralesNATicarcillinEnterobacteralesNA816FALSEFALSEFALSENAEnterobacterales
17EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATicarcillinEnterobacterales75 mcg2320FALSEFALSEFALSENAEnterobacterales
18EUCAST 20199.0humanhumanMICNAEnterobacteralesNATicarcillin-clavulanic acidEnterobacteralesNA816FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Enterobacterales
19EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATicarcillin-clavulanic acidEnterobacterales75/10 mcg2320FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Enterobacterales
20EUCAST 20199.0humanhumanMICNAEnterobacteralesNATemocillinEnterobacteralesNANoteNoteFALSEFALSEFALSE[5] Breakpoints still under consideration.Enterobacterales
21EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATemocillinEnterobacteralesNANoteNoteFALSEFALSEFALSE[5] Breakpoints still under consideration.Enterobacterales
22EUCAST 20199.0humanhumanMICNAEnterobacteralesNAMecillinam (uncomplicated UTI only) E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacteralesNA88FALSEFALSEFALSE[6] Agar dilution is the reference method for mecillinam MIC determination. | [D] Ignore isolated colonies within the inhibition zone for E. coli.Enterobacterales
23EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAMecillinam (uncomplicated UTI only) E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacterales10 mcg1515FALSEFALSEFALSE[6] Agar dilution is the reference method for mecillinam MIC determination. | [D] Ignore isolated colonies within the inhibition zone for E. coli.Enterobacterales
24EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefadroxil (uncomplicated UTI only)EnterobacteralesNA1616FALSEFALSEFALSENAEnterobacterales
25EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefadroxil (uncomplicated UTI only)Enterobacterales30 mcg1212FALSEFALSEFALSENAEnterobacterales
26EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefalexin (uncomplicated UTI only)EnterobacteralesNA1616FALSEFALSEFALSENAEnterobacterales
27EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefalexin (uncomplicated UTI only)Enterobacterales30 mcg1414FALSEFALSEFALSENAEnterobacterales
28EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefepimeEnterobacteralesNA14FALSEFALSEFALSENAEnterobacterales
29EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefepimeEnterobacterales30 mcg2724FALSEFALSEFALSENAEnterobacterales
30EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefixime (uncomplicated UTI only)EnterobacteralesNA11FALSEFALSEFALSENAEnterobacterales
31EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefixime (uncomplicated UTI only)Enterobacterales5 mcg1717FALSEFALSEFALSENAEnterobacterales
32EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefotaximeEnterobacteralesNA12FALSEFALSEFALSENAEnterobacterales
33EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefotaximeEnterobacterales5 mcg2017FALSEFALSEFALSENAEnterobacterales
34EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefoxitin (screen)Enterobacterales30 mcg1919FALSEFALSEFALSENAEnterobacterales
35EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefpodoxime (uncomplicated UTI only)EnterobacteralesNA11FALSEFALSEFALSENAEnterobacterales
36EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefpodoxime (uncomplicated UTI only)Enterobacterales10 mcg2121FALSEFALSEFALSENAEnterobacterales
37EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftarolineEnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
38EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftarolineEnterobacterales5 mcg2323FALSEFALSEFALSENAEnterobacterales
39EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftazidimeEnterobacteralesNA14FALSEFALSEFALSENAEnterobacterales
40EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftazidimeEnterobacterales10 mcg2219FALSEFALSEFALSENAEnterobacterales
41EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftazidime-avibactamEnterobacteralesNA88FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Enterobacterales
42EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftazidime-avibactamEnterobacterales10/4 mcg1313FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Enterobacterales
43EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftibuten (UTI only)EnterobacteralesNA11FALSEFALSEFALSENAEnterobacterales
44EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftibuten (UTI only)Enterobacterales30 mcg2323FALSEFALSEFALSENAEnterobacterales
45EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftobiproleEnterobacteralesNA0.250.25FALSEFALSEFALSENAEnterobacterales
46EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftobiproleEnterobacterales5 mcg2323FALSEFALSEFALSENAEnterobacterales
47EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftolozane-tazobactamEnterobacteralesNA11FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
48EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftolozane-tazobactamEnterobacterales30/10 mcg2323FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
49EUCAST 20199.0humanhumanMICNAEnterobacteralesNACeftriaxoneEnterobacteralesNA12FALSEFALSEFALSENAEnterobacterales
50EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACeftriaxoneEnterobacterales30 mcg2522FALSEFALSEFALSENAEnterobacterales
51EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefuroxime iv, E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacteralesNA88FALSEFALSEFALSENAEnterobacterales
52EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefuroxime iv, E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacterales30 mcg1919FALSEFALSEFALSENAEnterobacterales
53EUCAST 20199.0humanhumanMICNAEnterobacteralesNACefuroxime oral (uncomplicated UTI only), E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacteralesNA88FALSEFALSEFALSENAEnterobacterales
54EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACefuroxime oral (uncomplicated UTI only), E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacterales30 mcg1919FALSEFALSEFALSENAEnterobacterales
55EUCAST 20199.0humanhumanMICNAEnterobacteralesNAErtapenemEnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
56EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAErtapenemEnterobacterales10 mcg2525FALSEFALSEFALSENAEnterobacterales
57EUCAST 20199.0humanhumanMICNAEnterobacteralesNAImipenemEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
58EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAImipenemEnterobacterales10 mcg2217FALSEFALSEFALSENAEnterobacterales
59EUCAST 20199.0humanhumanMICNAEnterobacteralesNAImipenem, Morganella morganii,Proteus spp. and Providencia spp.EnterobacteralesNA0.1254FALSEFALSEFALSENAEnterobacterales
60EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAImipenem, Morganella morganii,Proteus spp. and Providencia spp.Enterobacterales10 mcg5017FALSEFALSEFALSENAEnterobacterales
61EUCAST 20199.0humanhumanMICNAEnterobacteralesNAMeropenemEnterobacteralesNA28FALSEFALSEFALSENAEnterobacterales
62EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAMeropenemEnterobacterales10 mcg2216FALSEFALSEFALSENAEnterobacterales
63EUCAST 20199.0humanhumanMICNAEnterobacteralesNAMeropenem-vaborbactamEnterobacteralesNA88FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Enterobacterales
64EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAMeropenem-vaborbactamEnterobacteralesIP mcgIPIPFALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Enterobacterales
65EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAztreonamEnterobacteralesNA14FALSEFALSEFALSENAEnterobacterales
66EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAztreonamEnterobacterales30 mcg2621FALSEFALSEFALSENAEnterobacterales
67EUCAST 20199.0humanhumanMICNAEnterobacteralesNACiprofloxacinEnterobacteralesNA0.250.5FALSEFALSEFALSENAEnterobacterales
68EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACiprofloxacinEnterobacterales5 mcg2522FALSEFALSEFALSENAEnterobacterales
69EUCAST 20199.0humanhumanMICNAEnterobacteralesNACiprofloxacin, Salmonella spp.EnterobacteralesNA0.060.06FALSEFALSEFALSE[A] Tests with a ciprofloxacin 5 µg disk will not reliably detect low-level resistance in Salmonella spp. To screen for ciprofloxacin resistance in Salmonella spp., use the pefloxacin 5 µg disk. See NoteEnterobacterales
70EUCAST 20199.0humanhumanDISKNAEnterobacteralesNACiprofloxacin, Salmonella spp.EnterobacteralesNANoteNoteFALSEFALSEFALSE[A] Tests with a ciprofloxacin 5 µg disk will not reliably detect low-level resistance in Salmonella spp. To screen for ciprofloxacin resistance in Salmonella spp., use the pefloxacin 5 µg disk. See NoteEnterobacterales
71EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAPefloxacin (screen),Salmonella spp.Enterobacterales5 mcg2424FALSEFALSEFALSE[B] | [B] Susceptibility of Salmonella spp. to ciprofloxacin can be inferred from pefloxacin disk diffusion susceptibility.Enterobacterales
72EUCAST 20199.0humanhumanMICNAEnterobacteralesNALevofloxacinEnterobacteralesNA0.51FALSEFALSEFALSENAEnterobacterales
73EUCAST 20199.0humanhumanDISKNAEnterobacteralesNALevofloxacinEnterobacterales5 mcg2319FALSEFALSEFALSENAEnterobacterales
74EUCAST 20199.0humanhumanMICNAEnterobacteralesNAMoxifloxacinEnterobacteralesNA0.250.25FALSEFALSEFALSENAEnterobacterales
75EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAMoxifloxacinEnterobacterales5 mcg2222FALSEFALSEFALSENAEnterobacterales
76EUCAST 20199.0humanhumanMICNAEnterobacteralesNANorfloxacin (uncomplicated UTI only)EnterobacteralesNA0.51FALSEFALSEFALSENAEnterobacterales
77EUCAST 20199.0humanhumanDISKNAEnterobacteralesNANorfloxacin (uncomplicated UTI only)Enterobacterales10 mcg2219FALSEFALSEFALSENAEnterobacterales
78EUCAST 20199.0humanhumanMICNAEnterobacteralesNAOfloxacinEnterobacteralesNA0.250.5FALSEFALSEFALSENAEnterobacterales
79EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAOfloxacinEnterobacterales5 mcg2422FALSEFALSEFALSENAEnterobacterales
80EUCAST 20199.0humanhumanMICNAEnterobacteralesNAAmikacinEnterobacteralesNA816FALSEFALSEFALSENAEnterobacterales
81EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAAmikacinEnterobacterales30 mcg1815FALSEFALSEFALSENAEnterobacterales
82EUCAST 20199.0humanhumanMICNAEnterobacteralesNAGentamicinEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
83EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAGentamicinEnterobacterales10 mcg1714FALSEFALSEFALSENAEnterobacterales
84EUCAST 20199.0humanhumanMICNAEnterobacteralesNANetilmicinEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
85EUCAST 20199.0humanhumanDISKNAEnterobacteralesNANetilmicinEnterobacterales10 mcg1512FALSEFALSEFALSENAEnterobacterales
86EUCAST 20199.0humanhumanMICNAEnterobacteralesNATobramycinEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
87EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATobramycinEnterobacterales10 mcg1714FALSEFALSEFALSENAEnterobacterales
88EUCAST 20199.0humanhumanMICNAEnterobacteralesNAEravacycline, E. coliEnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
89EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAEravacycline, E. coliEnterobacteralesIP mcgIPIPFALSEFALSEFALSENAEnterobacterales
90EUCAST 20199.0humanhumanMICNAEnterobacteralesNATigecycline,E. coli and C. koseriEnterobacteralesNA0.50.5FALSEFALSEFALSE[3/A] For other Enterobacterales, the activity of tigecycline varies from insufficient in Proteus spp., Morganella morganii and Providencia spp. to variable in other species. For more information, see http://www.eucast.org/guidance_documents/. | [2] Tigecycline has poor activity against Morganella morganii, Proteus spp. and Providencia spp. | [2] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use. | [B] Zone diameter breakpoints validated for E. coli only. For C.koseri, use an MIC method.Enterobacterales
91EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATigecycline,E. coli and C. koseriEnterobacterales15 mcg1818FALSEFALSEFALSE[3/A] For other Enterobacterales, the activity of tigecycline varies from insufficient in Proteus spp., Morganella morganii and Providencia spp. to variable in other species. For more information, see http://www.eucast.org/guidance_documents/. | [2] Tigecycline has poor activity against Morganella morganii, Proteus spp. and Providencia spp. | [2] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use. | [B] Zone diameter breakpoints validated for E. coli only. For C.koseri, use an MIC method.Enterobacterales
92EUCAST 20199.0humanhumanMICNAEnterobacteralesNAChloramphenicolEnterobacteralesNA88FALSEFALSEFALSENAEnterobacterales
93EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAChloramphenicolEnterobacterales30 mcg1717FALSEFALSEFALSENAEnterobacterales
94EUCAST 20199.0humanhumanMICNAEnterobacteralesNAColistinEnterobacteralesNA22FALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Enterobacterales
95EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAColistinEnterobacteralesNANoteNoteFALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Enterobacterales
96EUCAST 20199.0humanhumanMICNAEnterobacteralesNAFosfomycin ivEnterobacteralesNA3232FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
97EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAFosfomycin ivEnterobacterales200 mcg2424FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
98EUCAST 20199.0humanhumanMICNAEnterobacteralesNAFosfomycin oral (uncomplicated UTI only)EnterobacteralesNA3232FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
99EUCAST 20199.0humanhumanDISKNAEnterobacteralesNAFosfomycin oral (uncomplicated UTI only)Enterobacterales200 mcg2424FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
100EUCAST 20199.0humanhumanMICNAEnterobacteralesNANitrofurantoin (uncomplicated UTI only), E. coliEnterobacteralesNA6464FALSEFALSEFALSENAEnterobacterales
101EUCAST 20199.0humanhumanDISKNAEnterobacteralesNANitrofurantoin (uncomplicated UTI only), E. coliEnterobacterales100 mcg1111FALSEFALSEFALSENAEnterobacterales
102EUCAST 20199.0humanhumanMICNAEnterobacteralesNANitroxoline (uncomplicated UTI only), E. coliEnterobacteralesNA1616FALSEFALSEFALSENAEnterobacterales
103EUCAST 20199.0humanhumanDISKNAEnterobacteralesNANitroxoline (uncomplicated UTI only), E. coliEnterobacterales30 mcg1515FALSEFALSEFALSENAEnterobacterales
104EUCAST 20199.0humanhumanMICNAEnterobacteralesNATrimethoprim (uncomplicated UTI only)EnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
105EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATrimethoprim (uncomplicated UTI only)Enterobacterales5 mcg1815FALSEFALSEFALSENAEnterobacterales
106EUCAST 20199.0humanhumanMICNAEnterobacteralesNATrimethoprim-sulfamethoxazoleEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
107EUCAST 20199.0humanhumanDISKNAEnterobacteralesNATrimethoprim-sulfamethoxazoleEnterobacterales1.25/23.75 mcg1411FALSEFALSEFALSENAEnterobacterales
108EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAPiperacillinPseudomonas spp.NA1616FALSEFALSEFALSENAPseudomonas
109EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAPiperacillinPseudomonas spp.30 mcg1818FALSEFALSEFALSENAPseudomonas
110EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAPiperacillin-tazobactamPseudomonas spp.NA1616FALSEFALSEFALSE[1] Breakpoints are based on high dose therapy, see table of dosages. | [1] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
111EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAPiperacillin-tazobactamPseudomonas spp.30/6 mcg1818FALSEFALSEFALSE[1] Breakpoints are based on high dose therapy, see table of dosages. | [1] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
112EUCAST 20199.0humanhumanMICNAPseudomonas spp.NATicarcillinPseudomonas spp.NA1616FALSEFALSEFALSENAPseudomonas
113EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NATicarcillinPseudomonas spp.75 mcg1818FALSEFALSEFALSENAPseudomonas
114EUCAST 20199.0humanhumanMICNAPseudomonas spp.NATicarcillin-clavulanic acidPseudomonas spp.NA1616FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Pseudomonas
115EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NATicarcillin-clavulanic acidPseudomonas spp.75/10 mcg1818FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Pseudomonas
116EUCAST 20199.0humanhumanMICNAPseudomonas spp.NACefepimePseudomonas spp.NA88FALSEFALSEFALSENAPseudomonas
117EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NACefepimePseudomonas spp.30 mcg2121FALSEFALSEFALSENAPseudomonas
118EUCAST 20199.0humanhumanMICNAPseudomonas spp.NACeftazidimePseudomonas spp.NA88FALSEFALSEFALSENAPseudomonas
119EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NACeftazidimePseudomonas spp.10 mcg1717FALSEFALSEFALSENAPseudomonas
120EUCAST 20199.0humanhumanMICNAPseudomonas spp.NACeftazidime-avibactam, P. aeruginosaPseudomonas spp.NA88FALSEFALSEFALSE[1] Breakpoints are based on high dose therapy, see table of dosages. | [1] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Pseudomonas
121EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NACeftazidime-avibactam, P. aeruginosaPseudomonas spp.10/4 mcg1717FALSEFALSEFALSE[1] Breakpoints are based on high dose therapy, see table of dosages. | [1] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Pseudomonas
122EUCAST 20199.0humanhumanMICNAPseudomonas spp.NACeftobiprolePseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
123EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NACeftobiprolePseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
124EUCAST 20199.0humanhumanMICNAPseudomonas spp.NACeftolozane-tazobactam, P. aeruginosaPseudomonas spp.NA44FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
125EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NACeftolozane-tazobactam, P. aeruginosaPseudomonas spp.30/10 mcg2424FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
126EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAImipenemPseudomonas spp.NA44FALSEFALSEFALSENAPseudomonas
127EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAImipenemPseudomonas spp.10 mcg2020FALSEFALSEFALSENAPseudomonas
128EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAMeropenemPseudomonas spp.NA28FALSEFALSEFALSENAPseudomonas
129EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAMeropenemPseudomonas spp.10 mcg2418FALSEFALSEFALSENAPseudomonas
130EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAMeropenem-vaborbactam, P. aeruginosaPseudomonas spp.NA88FALSEFALSEFALSE[1] Breakpoints are based on high dose therapy, see table of dosages. | [1] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Pseudomonas
131EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAMeropenem-vaborbactam, P. aeruginosaPseudomonas spp.IP mcgIPIPFALSEFALSEFALSE[1] Breakpoints are based on high dose therapy, see table of dosages. | [1] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Pseudomonas
132EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAAztreonamPseudomonas spp.NA1616FALSEFALSEFALSENAPseudomonas
133EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAAztreonamPseudomonas spp.30 mcg1818FALSEFALSEFALSENAPseudomonas
134EUCAST 20199.0humanhumanMICNAPseudomonas spp.NACiprofloxacinPseudomonas spp.NA0.50.5FALSEFALSEFALSENAPseudomonas
135EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NACiprofloxacinPseudomonas spp.5 mcg2626FALSEFALSEFALSENAPseudomonas
136EUCAST 20199.0humanhumanMICNAPseudomonas spp.NALevofloxacinPseudomonas spp.NA11FALSEFALSEFALSENAPseudomonas
137EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NALevofloxacinPseudomonas spp.5 mcg2222FALSEFALSEFALSENAPseudomonas
138EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAAmikacinPseudomonas spp.NA816FALSEFALSEFALSENAPseudomonas
139EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAAmikacinPseudomonas spp.30 mcg1815FALSEFALSEFALSENAPseudomonas
140EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAGentamicinPseudomonas spp.NA44FALSEFALSEFALSENAPseudomonas
141EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAGentamicinPseudomonas spp.10 mcg1515FALSEFALSEFALSENAPseudomonas
142EUCAST 20199.0humanhumanMICNAPseudomonas spp.NANetilmicinPseudomonas spp.NA44FALSEFALSEFALSENAPseudomonas
143EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NANetilmicinPseudomonas spp.10 mcg1212FALSEFALSEFALSENAPseudomonas
144EUCAST 20199.0humanhumanMICNAPseudomonas spp.NATobramycinPseudomonas spp.NA44FALSEFALSEFALSENAPseudomonas
145EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NATobramycinPseudomonas spp.10 mcg1616FALSEFALSEFALSENAPseudomonas
146EUCAST 20199.0humanhumanMICNAPseudomonas spp.NAColistinPseudomonas spp.NA22FALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Pseudomonas
147EUCAST 20199.0humanhumanDISKNAPseudomonas spp.NAColistinPseudomonas spp.NANoteNoteFALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Pseudomonas
148EUCAST 20199.0humanhumanMICNAStenotrophomonas maltophiliaNATrimethoprim-sulfamethoxazoleStenotrophomonas maltophiliaNA44FALSEFALSEFALSE[A] Isolates showing any sign of inhibition zone ≥ 16 mm should be reported susceptible and growth within the inhibition zone should be ignored. The density of growth within the zone may vary from a fine haze to substantial growth (see pictures below).S.maltophilia
149EUCAST 20199.0humanhumanDISKNAStenotrophomonas maltophiliaNATrimethoprim-sulfamethoxazoleStenotrophomonas maltophilia1.25/23.75 mcg1616FALSEFALSEFALSE[A] Isolates showing any sign of inhibition zone ≥ 16 mm should be reported susceptible and growth within the inhibition zone should be ignored. The density of growth within the zone may vary from a fine haze to substantial growth (see pictures below).S.maltophilia
150EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAAmpicillin-sulbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
151EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAAmpicillin-sulbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
152EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAPiperacillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
153EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAPiperacillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
154EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAPiperacillin-tazobactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
155EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAPiperacillin-tazobactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
156EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NATicarcillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
157EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NATicarcillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
158EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NATicarcillin-clavulanic acidAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
159EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NATicarcillin-clavulanic acidAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
160EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAImipenemAcinetobacter spp.NA24FALSEFALSEFALSENAAcinetobacter
161EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAImipenemAcinetobacter spp.10 mcg2421FALSEFALSEFALSENAAcinetobacter
162EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAMeropenemAcinetobacter spp.NA28FALSEFALSEFALSENAAcinetobacter
163EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAMeropenemAcinetobacter spp.10 mcg2115FALSEFALSEFALSENAAcinetobacter
164EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAMeropenem-vaborbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
165EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAMeropenem-vaborbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
166EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NACiprofloxacinAcinetobacter spp.NA0.061FALSEFALSEFALSENAAcinetobacter
167EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NACiprofloxacinAcinetobacter spp.5 mcg5021FALSEFALSEFALSENAAcinetobacter
168EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NALevofloxacinAcinetobacter spp.NA0.51FALSEFALSEFALSENAAcinetobacter
169EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NALevofloxacinAcinetobacter spp.5 mcg2320FALSEFALSEFALSENAAcinetobacter
170EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAAmikacinAcinetobacter spp.NA816FALSEFALSEFALSENAAcinetobacter
171EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAAmikacinAcinetobacter spp.30 mcg1917FALSEFALSEFALSENAAcinetobacter
172EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAGentamicinAcinetobacter spp.NA44FALSEFALSEFALSENAAcinetobacter
173EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAGentamicinAcinetobacter spp.10 mcg1717FALSEFALSEFALSENAAcinetobacter
174EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NANetilmicinAcinetobacter spp.NA44FALSEFALSEFALSENAAcinetobacter
175EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NANetilmicinAcinetobacter spp.10 mcg1616FALSEFALSEFALSENAAcinetobacter
176EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NATobramycinAcinetobacter spp.NA44FALSEFALSEFALSENAAcinetobacter
177EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NATobramycinAcinetobacter spp.10 mcg1717FALSEFALSEFALSENAAcinetobacter
178EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAEravacyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
179EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAEravacyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
180EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAMinocyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
181EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAMinocyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
182EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NATigecyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
183EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NATigecyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
184EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NAColistinAcinetobacter spp.NA22FALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Acinetobacter
185EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NAColistinAcinetobacter spp.NANoteNoteFALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Acinetobacter
186EUCAST 20199.0humanhumanMICNAAcinetobacter spp.NATrimethoprim-sulfamethoxazoleAcinetobacter spp.NA24FALSEFALSEFALSENAAcinetobacter
187EUCAST 20199.0humanhumanDISKNAAcinetobacter spp.NATrimethoprim-sulfamethoxazoleAcinetobacter spp.1.25/23.75 mcg1411FALSEFALSEFALSENAAcinetobacter
188EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NABenzylpenicillin,S. aureusStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [B] For S. aureus, disk diffusion is more reliable than MIC determination for detection of penicillinase producers, provided the zone diameter is measured AND the zone edge closely inspected (see pictures below). Examine the zone edge with transmitted light (plate held up to light). If the zone diameter is <26 mm, then report resistant. If the zone diameter is ≥26 mm AND the zone edge is sharp, then report resistant. If not sharp, then report susceptible and if uncertain, then report resistant. Chromogenic cephalosporin-based beta-lactamase tests do not reliably detect staphylococcal penicillinase.Staphylococcus
189EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NABenzylpenicillin,S. aureusStaphylococcus spp.1 unit2626FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [B] For S. aureus, disk diffusion is more reliable than MIC determination for detection of penicillinase producers, provided the zone diameter is measured AND the zone edge closely inspected (see pictures below). Examine the zone edge with transmitted light (plate held up to light). If the zone diameter is <26 mm, then report resistant. If the zone diameter is ≥26 mm AND the zone edge is sharp, then report resistant. If not sharp, then report susceptible and if uncertain, then report resistant. Chromogenic cephalosporin-based beta-lactamase tests do not reliably detect staphylococcal penicillinase.Staphylococcus
190EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NABenzylpenicillin,S. lugdunensisStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
191EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NABenzylpenicillin,S. lugdunensisStaphylococcus spp.1 unit2626FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
192EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NABenzylpenicillin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci.Staphylococcus
193EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAmpicillin,S. saprophyticusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
194EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAmpicillin,S. saprophyticusStaphylococcus spp.2 mcg1818FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
195EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAmpicillin-sulbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
196EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAmpicillin-sulbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
197EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAmoxicillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
198EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAmoxicillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
199EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAmoxicillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
200EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAmoxicillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
201EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAPiperacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
202EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAPiperacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
203EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAPiperacillin-tazobactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
204EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAPiperacillin-tazobactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
205EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATicarcillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
206EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATicarcillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
207EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATicarcillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
208EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATicarcillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
209EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAPhenoxymethylpenicillin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
210EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAPhenoxymethylpenicillin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
211EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAPhenoxymethylpenicillin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [2] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci.Staphylococcus
212EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAOxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [E] For screening for methicillin resistance in S. pseudintermedius, see Note C on cephalosporins.Staphylococcus
213EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAOxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents. | [E] For screening for methicillin resistance in S. pseudintermedius, see Note C on cephalosporins.Staphylococcus
214EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
215EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
216EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NADicloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
217EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NADicloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
218EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAFlucloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
219EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAFlucloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers, which make them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. When staphylococci test as susceptible to benzylpenicillin and cefoxitin they can be reported as susceptible to the above agents. However, the efficacy of oral formulations, particularly phenoxymethylpenicillin, is uncertain. Isolates that test as resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin), nafcillin and many cephalosporins. With the exception of ceftaroline and ceftobiprole, cefoxitin-resistant isolates are resistant to all beta-lactam agents.Staphylococcus
220EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefaclorStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
221EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefaclorStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
222EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefadroxilStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
223EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefadroxilStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
224EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefalexinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
225EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefalexinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
226EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefazolinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
227EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefazolinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
228EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefepimeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
229EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefepimeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
230EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefotaximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
231EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefotaximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
232EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefoxitin (screen), S. aureus and coagulase-negative staphylococci other than S. epidermidisStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[2] For dosing, see table of dosages. 2.S. aureus and S. lugdunensis with cefoxitin MIC values >4 mg/L and S. saprophyticus with cefoxitin MIC values >8 mg/L are methicillin resistant, mostly due to the presence of the mecA or mecC gene. Disk diffusion reliably predicts methicillin resistance. | [3] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
233EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefoxitin (screen), S. aureus and coagulase-negative staphylococci other than S. epidermidisStaphylococcus spp.30 mcg2222FALSEFALSEFALSE[2] For dosing, see table of dosages. 2.S. aureus and S. lugdunensis with cefoxitin MIC values >4 mg/L and S. saprophyticus with cefoxitin MIC values >8 mg/L are methicillin resistant, mostly due to the presence of the mecA or mecC gene. Disk diffusion reliably predicts methicillin resistance. | [3] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
234EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefoxitin (screen), S. epidermidisStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[3] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
235EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefoxitin (screen), S. epidermidisStaphylococcus spp.30 mcg2525FALSEFALSEFALSE[3] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
236EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefoxitin (screen), S. pseudintermediusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[C] Cefoxitin screen for methicillin resistance in S. pseudintermedius is less predictive of the presence of mecA than in other staphylococci. Use the oxacillin 1 µg disk with zone diameter breakpoints S≥20, R<20 mm to screen for methicillin resistance.Staphylococcus
237EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefpodoximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
238EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefpodoximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
239EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACeftaroline, S. aureus (indications other than pneumonia)Staphylococcus spp.NA12FALSEFALSEFALSE[4/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
240EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACeftaroline, S. aureus (indications other than pneumonia)Staphylococcus spp.5 mcg2017FALSEFALSEFALSE[4/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
241EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACeftaroline, S. aureus (pneumonia)Staphylococcus spp.NA11FALSEFALSEFALSE[4/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
242EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACeftaroline, S. aureus (pneumonia)Staphylococcus spp.5 mcg2020FALSEFALSEFALSE[4/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
243EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACeftobiprole, S. aureusStaphylococcus spp.NA22FALSEFALSEFALSE[6/F] Methicillin-susceptible isolates can be reported susceptible to ceftobiprole without further testing.Staphylococcus
244EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACeftobiprole, S. aureusStaphylococcus spp.5 mcg1717FALSEFALSEFALSE[6/F] Methicillin-susceptible isolates can be reported susceptible to ceftobiprole without further testing.Staphylococcus
245EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACeftriaxoneStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
246EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACeftriaxoneStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
247EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefuroxime ivStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
248EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefuroxime ivStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
249EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACefuroxime oralStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
250EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACefuroxime oralStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 4/D and 6/F.Staphylococcus
251EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAErtapenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
252EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAErtapenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
253EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAImipenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
254EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAImipenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
255EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAMeropenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
256EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAMeropenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
257EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAMeropenem-vaborbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
258EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAMeropenem-vaborbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
259EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACiprofloxacin, S. aureusStaphylococcus spp.NA11FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
260EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACiprofloxacin, S. aureusStaphylococcus spp.5 mcg2121FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
261EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NACiprofloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
262EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NACiprofloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg2424FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
263EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NALevofloxacin, S. aureusStaphylococcus spp.NA11FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
264EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NALevofloxacin, S. aureusStaphylococcus spp.5 mcg2222FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
265EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NALevofloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
266EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NALevofloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg2424FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
267EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAMoxifloxacin, S. aureusStaphylococcus spp.NA0.250.25FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
268EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAMoxifloxacin, S. aureusStaphylococcus spp.5 mcg2525FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
269EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAMoxifloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA0.250.25FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
270EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAMoxifloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg2828FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
271EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NANorfloxacin (screen)Staphylococcus spp.10 mcg17NoteFALSEFALSEFALSE[B] | [B] Isolates categorised as susceptible to norfloxacin can be reported susceptible to ciprofloxacin, levofloxacin, moxifloxacin and ofloxacin. Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Staphylococcus
272EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAOfloxacin, S. aureusStaphylococcus spp.NA11FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
273EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAOfloxacin, S. aureusStaphylococcus spp.5 mcg2020FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
274EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAOfloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
275EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAOfloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg2424FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
276EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAmikacin, S. aureusStaphylococcus spp.NA816FALSEFALSEFALSENAStaphylococcus
277EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAmikacin, S. aureusStaphylococcus spp.30 mcg1816FALSEFALSEFALSENAStaphylococcus
278EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAmikacin,Coagulase-negative staphylococciStaphylococcus spp.NA816FALSEFALSEFALSENAStaphylococcus
279EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAmikacin,Coagulase-negative staphylococciStaphylococcus spp.30 mcg2219FALSEFALSEFALSENAStaphylococcus
280EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAGentamicin, S. aureusStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
281EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAGentamicin, S. aureusStaphylococcus spp.10 mcg1818FALSEFALSEFALSENAStaphylococcus
282EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAGentamicin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
283EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAGentamicin, Coagulase-negative staphylococciStaphylococcus spp.10 mcg2222FALSEFALSEFALSENAStaphylococcus
284EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NANetilmicin, S. aureusStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
285EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NANetilmicin, S. aureusStaphylococcus spp.10 mcg1818FALSEFALSEFALSENAStaphylococcus
286EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NANetilmicin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
287EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NANetilmicin, Coagulase-negative staphylococciStaphylococcus spp.10 mcg2222FALSEFALSEFALSENAStaphylococcus
288EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATobramycin, S. aureusStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
289EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATobramycin, S. aureusStaphylococcus spp.10 mcg1818FALSEFALSEFALSENAStaphylococcus
290EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATobramycin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
291EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATobramycin, Coagulase-negative staphylococciStaphylococcus spp.10 mcg2222FALSEFALSEFALSENAStaphylococcus
292EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NADalbavancinStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
293EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NADalbavancinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
294EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAOritavancin, S. aureusStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
295EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAOritavancin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
296EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATeicoplanin, S. aureusStaphylococcus spp.NA22FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
297EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATeicoplanin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
298EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATeicoplanin, Coagulase-negative staphylococciStaphylococcus spp.NA44FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
299EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATeicoplanin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
300EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATelavancin,MRSAStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
301EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATelavancin,MRSAStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
302EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAVancomycin, S. aureusStaphylococcus spp.NA22FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
303EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAVancomycin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
304EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAVancomycin, Coagulase-negative staphylococciStaphylococcus spp.NA44FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
305EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAVancomycin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
306EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAAzithromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
307EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAAzithromycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
308EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAClarithromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
309EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAClarithromycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
310EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAErythromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
311EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAErythromycinStaphylococcus spp.15 mcg2118FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
312EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NARoxithromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
313EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NARoxithromycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
314EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATelithromycinStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
315EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATelithromycinStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
316EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAClindamycinStaphylococcus spp.NA0.250.5FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-20 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Staphylococcus
317EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAClindamycinStaphylococcus spp.2 mcg2219FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-20 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Staphylococcus
318EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAQuinupristin-dalfopristinStaphylococcus spp.NA12FALSEFALSEFALSENAStaphylococcus
319EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAQuinupristin-dalfopristinStaphylococcus spp.15 mcg2118FALSEFALSEFALSENAStaphylococcus
320EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NADoxycyclineStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
321EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NADoxycyclineStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
322EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAEravacycline, S. aureusStaphylococcus spp.NA0.250.25FALSEFALSEFALSENAStaphylococcus
323EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAEravacycline, S. aureusStaphylococcus spp.IP mcgIPIPFALSEFALSEFALSENAStaphylococcus
324EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAMinocyclineStaphylococcus spp.NA0.51FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
325EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAMinocyclineStaphylococcus spp.30 mcg2320FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
326EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATetracyclineStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
327EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATetracyclineStaphylococcus spp.30 mcg2219FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
328EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATigecyclineStaphylococcus spp.NA0.50.5FALSEFALSEFALSE[3] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Staphylococcus
329EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATigecyclineStaphylococcus spp.15 mcg1818FALSEFALSEFALSE[3] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Staphylococcus
330EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NALinezolidStaphylococcus spp.NA44FALSEFALSEFALSE[A] Examine zone edges with transmitted light (plate held up to light).Staphylococcus
331EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NALinezolidStaphylococcus spp.10 mcg2121FALSEFALSEFALSE[A] Examine zone edges with transmitted light (plate held up to light).Staphylococcus
332EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATedizolidStaphylococcus spp.NA0.50.5FALSEFALSEFALSE[1] Isolates susceptible to linezolid can be reported susceptible to tedizolid. | [B] Isolates susceptible to linezolid can be reported susceptible to tedizolid. For isolates resistant to linezolid, perform an MIC test.Staphylococcus
333EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATedizolidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1] Isolates susceptible to linezolid can be reported susceptible to tedizolid. | [B] Isolates susceptible to linezolid can be reported susceptible to tedizolid. For isolates resistant to linezolid, perform an MIC test.Staphylococcus
334EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAChloramphenicolStaphylococcus spp.NA88FALSEFALSEFALSENAStaphylococcus
335EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAChloramphenicolStaphylococcus spp.30 mcg1818FALSEFALSEFALSENAStaphylococcus
336EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NADaptomycinStaphylococcus spp.NA11FALSEFALSEFALSE[2] Daptomycin MICs must be determined in the presence of Ca (50 mg/L in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturers' instructions for commercial systems. | [A] Use an MIC method.Staphylococcus
337EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NADaptomycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[2] Daptomycin MICs must be determined in the presence of Ca (50 mg/L in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturers' instructions for commercial systems. | [A] Use an MIC method.Staphylococcus
338EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAFosfomycin ivStaphylococcus spp.NA3232FALSEFALSEFALSE[3] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [A] Use an MIC method.Staphylococcus
339EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAFosfomycin ivStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[3] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [A] Use an MIC method.Staphylococcus
340EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NAFusidic acidStaphylococcus spp.NA11FALSEFALSEFALSENAStaphylococcus
341EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NAFusidic acidStaphylococcus spp.10 mcg2424FALSEFALSEFALSENAStaphylococcus
342EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NANitrofurantoin (uncomplicated UTI only), S. saprophyticusStaphylococcus spp.NA6464FALSEFALSEFALSENAStaphylococcus
343EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NANitrofurantoin (uncomplicated UTI only), S. saprophyticusStaphylococcus spp.100 mcg1313FALSEFALSEFALSENAStaphylococcus
344EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NANitroxoline (uncomplicated UTI only), S. saprophyticusStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
345EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NANitroxoline (uncomplicated UTI only), S. saprophyticusStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
346EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NARifampicinStaphylococcus spp.NA0.060.5FALSEFALSEFALSENAStaphylococcus
347EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NARifampicinStaphylococcus spp.5 mcg2623FALSEFALSEFALSENAStaphylococcus
348EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATrimethoprim (uncomplicated UTI only)Staphylococcus spp.NA24FALSEFALSEFALSENAStaphylococcus
349EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATrimethoprim (uncomplicated UTI only)Staphylococcus spp.5 mcg1714FALSEFALSEFALSENAStaphylococcus
350EUCAST 20199.0humanhumanMICNAStaphylococcus spp.NATrimethoprim-sulfamethoxazoleStaphylococcus spp.NA24FALSEFALSEFALSENAStaphylococcus
351EUCAST 20199.0humanhumanDISKNAStaphylococcus spp.NATrimethoprim-sulfamethoxazoleStaphylococcus spp.1.25/23.75 mcg1714FALSEFALSEFALSENAStaphylococcus
352EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAAmpicillinEnterococcus spp.NA48FALSEFALSEFALSENAEnterococcus
353EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAAmpicillinEnterococcus spp.2 mcg108FALSEFALSEFALSENAEnterococcus
354EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAAmpicillin-sulbactamEnterococcus spp.NA48FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
355EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAAmpicillin-sulbactamEnterococcus spp.NANoteNoteFALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
356EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAAmoxicillinEnterococcus spp.NA48FALSEFALSEFALSE[A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
357EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAAmoxicillinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
358EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAAmoxicillin-clavulanic acidEnterococcus spp.NA48FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
359EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAAmoxicillin-clavulanic acidEnterococcus spp.NANoteNoteFALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
360EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAPiperacillinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[3/A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
361EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAPiperacillinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[3/A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
362EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAPiperacillin-tazobactamEnterococcus spp.NANoteNoteFALSEFALSEFALSE[3/A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
363EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAPiperacillin-tazobactamEnterococcus spp.NANoteNoteFALSEFALSEFALSE[3/A] Susceptibility to ampicillin, amoxicillin and piperacillin with and without beta-lactamase inhibitor can be inferred from ampicillin.Enterococcus
364EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAImipenemEnterococcus spp.NA48FALSEFALSEFALSENAEnterococcus
365EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAImipenemEnterococcus spp.10 mcg2118FALSEFALSEFALSENAEnterococcus
366EUCAST 20199.0humanhumanMICNAEnterococcus spp.NACiprofloxacin (uncomplicated UTI only)Enterococcus spp.NA44FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteEnterococcus
367EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NACiprofloxacin (uncomplicated UTI only)Enterococcus spp.5 mcg1515FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteEnterococcus
368EUCAST 20199.0humanhumanMICNAEnterococcus spp.NALevofloxacin (uncomplicated UTI only)Enterococcus spp.NA44FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteEnterococcus
369EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NALevofloxacin (uncomplicated UTI only)Enterococcus spp.5 mcg1515FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteEnterococcus
370EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NANorfloxacin (screen)Enterococcus spp.10 mcg1212FALSEFALSEFALSE[B] | [B] Susceptibility of ciprofloxacin and levofloxacin can be inferred from the norfloxacin susceptibility.Enterococcus
371EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAAmikacinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
372EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAAmikacinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
373EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAGentamicin (test for high-level aminoglycoside resistance)Enterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
374EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAGentamicin (test for high-level aminoglycoside resistance)Enterococcus spp.30 mcgNoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
375EUCAST 20199.0humanhumanMICNAEnterococcus spp.NANetilmicinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
376EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NANetilmicinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
377EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAStreptomycin (test for high-level streptomycin resistance)Enterococcus spp.NANoteNoteFALSEFALSEFALSE[3/B] Isolates with high-level gentamicin resistance may not be high-level resistant to streptomycin. Negative test: Isolates with streptomycin MIC ≤512 mg/L or a zone diameter ≥14 mm. The isolate is wild type for streptomycin and low-level intrinsic resistant. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with streptomycin MIC >512 mg/L or a zone diameter <14 mm. The isolate is high-level resistant to streptomycin. There will be no synergy with penicillins or glycopeptides.Enterococcus
378EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAStreptomycin (test for high-level streptomycin resistance)Enterococcus spp.300 mcgNoteNoteFALSEFALSEFALSE[3/B] Isolates with high-level gentamicin resistance may not be high-level resistant to streptomycin. Negative test: Isolates with streptomycin MIC ≤512 mg/L or a zone diameter ≥14 mm. The isolate is wild type for streptomycin and low-level intrinsic resistant. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with streptomycin MIC >512 mg/L or a zone diameter <14 mm. The isolate is high-level resistant to streptomycin. There will be no synergy with penicillins or glycopeptides.Enterococcus
379EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATobramycinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
380EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATobramycinEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] Gentamicin can be used to screen for high-level aminoglycoside resistance (HLAR). Negative test: Isolates with gentamicin MIC ≤128 mg/L or a zone diameter ≥8 mm. The isolate is wild type for gentamicin and low-level intrinsic resistant. For other aminoglycosides, this may not be the case. Synergy with penicillins or glycopeptides can be expected if the isolate is susceptible to the penicillin or glycopeptide. Positive test: Isolates with gentamicin MIC >128 mg/L or a zone diameter <8 mm. The isolate is high-level resistant to gentamicin and other aminoglycosides, except streptomycin which must be tested separately if required (see note 3/B). There will be no synergy with penicillins or glycopeptides.Enterococcus
381EUCAST 20199.0humanhumanMICNAEnterococcus spp.NADalbavancinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
382EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NADalbavancinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
383EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAOritavancinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
384EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAOritavancinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
385EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATeicoplaninEnterococcus spp.NA22FALSEFALSEFALSENAEnterococcus
386EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATeicoplaninEnterococcus spp.30 mcg1616FALSEFALSEFALSENAEnterococcus
387EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATelavancinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
388EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATelavancinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
389EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAVancomycinEnterococcus spp.NA44FALSEFALSEFALSE[A] Vancomycin susceptible enterococci exhibit sharp zone edges and do not exhibit colonies in the inhibition zone. Examine zone edges with transmitted light (plate held up to light). If the zone edge is fuzzy, colonies grow within the zone or if you are uncertain, then perform confirmatory testing with PCR or report resistant (see pictures below) even if the zone diameter is ≥ 12 mm. Isolates must not be reported susceptible before 24 h incubation.Enterococcus
390EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAVancomycinEnterococcus spp.5 mcg1212FALSEFALSEFALSE[A] Vancomycin susceptible enterococci exhibit sharp zone edges and do not exhibit colonies in the inhibition zone. Examine zone edges with transmitted light (plate held up to light). If the zone edge is fuzzy, colonies grow within the zone or if you are uncertain, then perform confirmatory testing with PCR or report resistant (see pictures below) even if the zone diameter is ≥ 12 mm. Isolates must not be reported susceptible before 24 h incubation.Enterococcus
391EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAQuinupristin-dalfopristin, E. faeciumEnterococcus spp.NA14FALSEFALSEFALSENAEnterococcus
392EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAQuinupristin-dalfopristin, E. faeciumEnterococcus spp.15 mcg2220FALSEFALSEFALSENAEnterococcus
393EUCAST 20199.0humanhumanMICNAEnterococcus spp.NAEravacyclineEnterococcus spp.NA0.1250.125FALSEFALSEFALSENAEnterococcus
394EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NAEravacyclineEnterococcus spp.IP mcgIPIPFALSEFALSEFALSENAEnterococcus
395EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATigecyclineEnterococcus spp.NA0.250.25FALSEFALSEFALSE[2] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Enterococcus
396EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATigecyclineEnterococcus spp.15 mcg1818FALSEFALSEFALSE[2] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Enterococcus
397EUCAST 20199.0humanhumanMICNAEnterococcus spp.NALinezolidEnterococcus spp.NA44FALSEFALSEFALSENAEnterococcus
398EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NALinezolidEnterococcus spp.10 mcg1919FALSEFALSEFALSENAEnterococcus
399EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATedizolidEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
400EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATedizolidEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
401EUCAST 20199.0humanhumanMICNAEnterococcus spp.NADaptomycinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
402EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NADaptomycinEnterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
403EUCAST 20199.0humanhumanMICNAEnterococcus spp.NANitrofurantoin (uncomplicated UTI only), E. faecalisEnterococcus spp.NA6464FALSEFALSEFALSENAEnterococcus
404EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NANitrofurantoin (uncomplicated UTI only), E. faecalisEnterococcus spp.100 mcg1515FALSEFALSEFALSENAEnterococcus
405EUCAST 20199.0humanhumanMICNAEnterococcus spp.NANitroxoline (uncomplicated UTI only)Enterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
406EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NANitroxoline (uncomplicated UTI only)Enterococcus spp.NAIEIEFALSEFALSEFALSENAEnterococcus
407EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATrimethoprim (uncomplicated UTI only)Enterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] The activity of trimethoprim and trimethoprim-sulfamethoxazole is uncertain against enterococci, and it is not possible to predict clinical outcome. The ECOFF to categorise isolates as wild type or non-wild type for both E. faecalis and E. faecium is 1 mg/L, with a corresponding zone diameter ECOFF of 21 mm for trimethoprim and 23 mm for trimethoprim-sulfamethoxazole.Enterococcus
408EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATrimethoprim (uncomplicated UTI only)Enterococcus spp.5 mcgNoteNoteFALSEFALSEFALSE[2/A] The activity of trimethoprim and trimethoprim-sulfamethoxazole is uncertain against enterococci, and it is not possible to predict clinical outcome. The ECOFF to categorise isolates as wild type or non-wild type for both E. faecalis and E. faecium is 1 mg/L, with a corresponding zone diameter ECOFF of 21 mm for trimethoprim and 23 mm for trimethoprim-sulfamethoxazole.Enterococcus
409EUCAST 20199.0humanhumanMICNAEnterococcus spp.NATrimethoprim-sulfamethoxazoleEnterococcus spp.NANoteNoteFALSEFALSEFALSE[2/A] The activity of trimethoprim and trimethoprim-sulfamethoxazole is uncertain against enterococci, and it is not possible to predict clinical outcome. The ECOFF to categorise isolates as wild type or non-wild type for both E. faecalis and E. faecium is 1 mg/L, with a corresponding zone diameter ECOFF of 21 mm for trimethoprim and 23 mm for trimethoprim-sulfamethoxazole.Enterococcus
410EUCAST 20199.0humanhumanDISKNAEnterococcus spp.NATrimethoprim-sulfamethoxazoleEnterococcus spp.1.25/23.75 mcgNoteNoteFALSEFALSEFALSE[2/A] The activity of trimethoprim and trimethoprim-sulfamethoxazole is uncertain against enterococci, and it is not possible to predict clinical outcome. The ECOFF to categorise isolates as wild type or non-wild type for both E. faecalis and E. faecium is 1 mg/L, with a corresponding zone diameter ECOFF of 21 mm for trimethoprim and 23 mm for trimethoprim-sulfamethoxazole.Enterococcus
411EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNABenzylpenicillinStreptococcus groups A, B, C and GNA0.250.25FALSEFALSEFALSENAStreptococcus A,B,C,G
412EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNABenzylpenicillinStreptococcus groups A, B, C and G1 unit1818FALSEFALSEFALSENAStreptococcus A,B,C,G
413EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAAmpicillinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
414EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAAmpicillinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
415EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAAmpicillin-sulbactamStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
416EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAAmpicillin-sulbactamStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
417EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAAmoxicillinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
418EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAAmoxicillinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
419EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAAmoxicillin-clavulanic acidStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
420EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAAmoxicillin-clavulanic acidStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
421EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAPiperacillinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
422EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAPiperacillinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
423EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAPiperacillin-tazobactamStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
424EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAPiperacillin-tazobactamStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
425EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAPhenoxymethylpenicillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
426EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAPhenoxymethylpenicillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
427EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACloxacillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
428EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACloxacillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
429EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNADicloxacillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
430EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNADicloxacillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
431EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAFlucloxacillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
432EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAFlucloxacillin Streptococcus groups A, C and GStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to penicillins is inferred from the benzylpenicillin susceptibility with the exception of phenoxymethylpenicillin and isoxazolylpenicillins for streptococcus group B.Streptococcus A,B,C,G
433EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefaclorStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
434EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefaclorStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
435EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefadroxilStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
436EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefadroxilStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
437EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefalexinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
438EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefalexinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
439EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefazolinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
440EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefazolinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
441EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefepimeStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
442EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefepimeStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
443EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefotaximeStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
444EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefotaximeStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
445EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefpodoximeStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
446EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefpodoximeStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
447EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACeftarolineStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
448EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACeftarolineStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
449EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACeftibutenStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
450EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACeftibutenStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
451EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACeftobiproleStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
452EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACeftobiproleStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
453EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACeftolozane-tazobactamStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
454EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACeftolozane-tazobactamStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
455EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACeftriaxoneStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
456EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACeftriaxoneStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
457EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefuroxime ivStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
458EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefuroxime ivStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
459EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNACefuroxime oralStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
460EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNACefuroxime oralStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to cephalosporins is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
461EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAErtapenemStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
462EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAErtapenemStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
463EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAImipenemStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
464EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAImipenemStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
465EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAMeropenemStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
466EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAMeropenemStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
467EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAMeropenem-vaborbactamStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
468EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAMeropenem-vaborbactamStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] The susceptibility of streptococcus groups A, B, C and G to carbapenems is inferred from the benzylpenicillin susceptibility.Streptococcus A,B,C,G
469EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNALevofloxacinStreptococcus groups A, B, C and GNA22FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStreptococcus A,B,C,G
470EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNALevofloxacinStreptococcus groups A, B, C and G5 mcg1717FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStreptococcus A,B,C,G
471EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAMoxifloxacinStreptococcus groups A, B, C and GNA0.50.5FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStreptococcus A,B,C,G
472EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAMoxifloxacinStreptococcus groups A, B, C and G5 mcg1919FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStreptococcus A,B,C,G
473EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNANorfloxacin (screen)Streptococcus groups A, B, C and G10 mcg12NoteFALSEFALSEFALSE[B] | [B] Isolates categorised as susceptible to norfloxacin can be reported susceptible to levofloxacin and moxifloxacin. Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Streptococcus A,B,C,G
474EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNADalbavancinStreptococcus groups A, B, C and GNA0.1250.125FALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Streptococcus A,B,C,G
475EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNADalbavancinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Streptococcus A,B,C,G
476EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAOritavancinStreptococcus groups A, B, C and GNA0.250.25FALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Streptococcus A,B,C,G
477EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAOritavancinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Streptococcus A,B,C,G
478EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATeicoplaninStreptococcus groups A, B, C and GNA22FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Streptococcus A,B,C,G
479EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATeicoplaninStreptococcus groups A, B, C and G30 mcg1515FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Streptococcus A,B,C,G
480EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATelavancinStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
481EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATelavancinStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
482EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAVancomycinStreptococcus groups A, B, C and GNA22FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Streptococcus A,B,C,G
483EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAVancomycinStreptococcus groups A, B, C and G5 mcg1313FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Streptococcus A,B,C,G
484EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAAzithromycinStreptococcus groups A, B, C and GNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
485EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAAzithromycinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
486EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAClarithromycinStreptococcus groups A, B, C and GNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
487EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAClarithromycinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
488EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAErythromycinStreptococcus groups A, B, C and GNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
489EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAErythromycinStreptococcus groups A, B, C and G15 mcg2118FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
490EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNARoxithromycinStreptococcus groups A, B, C and GNA0.51FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
491EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNARoxithromycinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Streptococcus A,B,C,G
492EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATelithromycinStreptococcus groups A, B, C and GNA0.250.5FALSEFALSEFALSENAStreptococcus A,B,C,G
493EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATelithromycinStreptococcus groups A, B, C and G15 mcg2017FALSEFALSEFALSENAStreptococcus A,B,C,G
494EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAClindamycinStreptococcus groups A, B, C and GNA0.50.5FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-16 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Streptococcus A,B,C,G
495EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAClindamycinStreptococcus groups A, B, C and G2 mcg1717FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-16 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Streptococcus A,B,C,G
496EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNADoxycyclineStreptococcus groups A, B, C and GNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Streptococcus A,B,C,G
497EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNADoxycyclineStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Streptococcus A,B,C,G
498EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAEravacyclineStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
499EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAEravacyclineStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
500EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAMinocyclineStreptococcus groups A, B, C and GNA0.51FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Streptococcus A,B,C,G
501EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAMinocyclineStreptococcus groups A, B, C and G30 mcg2320FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Streptococcus A,B,C,G
502EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATetracyclineStreptococcus groups A, B, C and GNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Streptococcus A,B,C,G
503EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATetracyclineStreptococcus groups A, B, C and G30 mcg2320FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Streptococcus A,B,C,G
504EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATigecyclineStreptococcus groups A, B, C and GNA0.1250.125FALSEFALSEFALSE[3] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Streptococcus A,B,C,G
505EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATigecyclineStreptococcus groups A, B, C and G15 mcg1919FALSEFALSEFALSE[3] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Streptococcus A,B,C,G
506EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNALinezolidStreptococcus groups A, B, C and GNA24FALSEFALSEFALSENAStreptococcus A,B,C,G
507EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNALinezolidStreptococcus groups A, B, C and G10 mcg1916FALSEFALSEFALSENAStreptococcus A,B,C,G
508EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATedizolidStreptococcus groups A, B, C and GNA0.50.5FALSEFALSEFALSE[2] Isolates susceptible to linezolid can be reported susceptible to tedizolid. | [A] Isolates susceptible to linezolid can be reported susceptible to tedizolid. For isolates resistant to linezolid, perform an MIC test.Streptococcus A,B,C,G
509EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATedizolidStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[2] Isolates susceptible to linezolid can be reported susceptible to tedizolid. | [A] Isolates susceptible to linezolid can be reported susceptible to tedizolid. For isolates resistant to linezolid, perform an MIC test.Streptococcus A,B,C,G
510EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAChloramphenicolStreptococcus groups A, B, C and GNA88FALSEFALSEFALSENAStreptococcus A,B,C,G
511EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAChloramphenicolStreptococcus groups A, B, C and G30 mcg1919FALSEFALSEFALSENAStreptococcus A,B,C,G
512EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNADaptomycinStreptococcus groups A, B, C and GNA11FALSEFALSEFALSE[2] Daptomycin MICs must be determined in the presence of Ca (50 mg/L in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [A] Use an MIC method.Streptococcus A,B,C,G
513EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNADaptomycinStreptococcus groups A, B, C and GNANoteNoteFALSEFALSEFALSE[2] Daptomycin MICs must be determined in the presence of Ca (50 mg/L in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [A] Use an MIC method.Streptococcus A,B,C,G
514EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNAFusidic acidStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
515EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNAFusidic acidStreptococcus groups A, B, C and GNAIEIEFALSEFALSEFALSENAStreptococcus A,B,C,G
516EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNANitrofurantoin (uncomplicated UTI only), S. agalactiae (group B streptococci)Streptococcus groups A, B, C and GNA6464FALSEFALSEFALSENAStreptococcus A,B,C,G
517EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNANitrofurantoin (uncomplicated UTI only), S. agalactiae (group B streptococci)Streptococcus groups A, B, C and G100 mcg1515FALSEFALSEFALSENAStreptococcus A,B,C,G
518EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNARifampicinStreptococcus groups A, B, C and GNA0.060.5FALSEFALSEFALSENAStreptococcus A,B,C,G
519EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNARifampicinStreptococcus groups A, B, C and G5 mcg2115FALSEFALSEFALSENAStreptococcus A,B,C,G
520EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATrimethoprim (uncomplicated UTI only), S. agalactiae (group B streptococci)Streptococcus groups A, B, C and GNA22FALSEFALSEFALSENAStreptococcus A,B,C,G
521EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATrimethoprim (uncomplicated UTI only), S. agalactiae (group B streptococci)Streptococcus groups A, B, C and G5 mcgIPIPFALSEFALSEFALSENAStreptococcus A,B,C,G
522EUCAST 20199.0humanhumanMICNAStreptococcus groups A, B, C and GNATrimethoprim-sulfamethoxazoleStreptococcus groups A, B, C and GNA12FALSEFALSEFALSENAStreptococcus A,B,C,G
523EUCAST 20199.0humanhumanDISKNAStreptococcus groups A, B, C and GNATrimethoprim-sulfamethoxazoleStreptococcus groups A, B, C and G1.25/23.75 mcg1815FALSEFALSEFALSENAStreptococcus A,B,C,G
524EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNABenzylpenicillin (indications other than meningitis)Streptococcus pneumoniaeNA0.062FALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
525EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNABenzylpenicillin (indications other than meningitis)Streptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
526EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNABenzylpenicillin (meningitis)Streptococcus pneumoniaeNA0.060.06FALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
527EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNABenzylpenicillin (meningitis)Streptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
528EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAmpicillinStreptococcus pneumoniaeNA0.52FALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
529EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAmpicillinStreptococcus pneumoniae2 mcg2216FALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
530EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAmpicillin-sulbactamStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
531EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAmpicillin-sulbactamStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
532EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAmoxicillin ivStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
533EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAmoxicillin ivStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
534EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAmoxicillin oralStreptococcus pneumoniaeNA0.51FALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [C] Perform an MIC or infer susceptibility from the ampicillin 2 µg disk diffusion test with ampicillin breakpoints S≥22, R<19 mm.S.pneumoniae
535EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAmoxicillin oralStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [C] Perform an MIC or infer susceptibility from the ampicillin 2 µg disk diffusion test with ampicillin breakpoints S≥22, R<19 mm.S.pneumoniae
536EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAmoxicillin-clavulanic acid ivStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
537EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAmoxicillin-clavulanic acid ivStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
538EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAmoxicillin-clavulanic acid oralStreptococcus pneumoniaeNA0.51FALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [C] Perform an MIC or infer susceptibility from the ampicillin 2 µg disk diffusion test with ampicillin breakpoints S≥22, R<19 mm.S.pneumoniae
539EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAmoxicillin-clavulanic acid oralStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [C] Perform an MIC or infer susceptibility from the ampicillin 2 µg disk diffusion test with ampicillin breakpoints S≥22, R<19 mm.S.pneumoniae
540EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAPiperacillinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
541EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAPiperacillinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
542EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAPiperacillin-tazobactamStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
543EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAPiperacillin-tazobactamStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [4/B] Susceptibility inferred from ampicillin (MIC or zone diameter).S.pneumoniae
544EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAPhenoxymethylpenicillinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
545EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAPhenoxymethylpenicillinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
546EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAOxacillin (screen)Streptococcus pneumoniae1 mcg20NoteFALSEFALSEFALSE[D] For interpretation of the oxacillin disk screen, see flow chart below. For oxacillin non-susceptible isolates, always determine the MIC of benzylpenicillin.S.pneumoniae
547EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACefaclorStreptococcus pneumoniaeNA0.030.5FALSEFALSEFALSENAS.pneumoniae
548EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACefaclorStreptococcus pneumoniae30 mcg5028FALSEFALSEFALSENAS.pneumoniae
549EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACefepimeStreptococcus pneumoniaeNA12FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
550EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACefepimeStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
551EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACefotaximeStreptococcus pneumoniaeNA0.52FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
552EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACefotaximeStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
553EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACefpodoximeStreptococcus pneumoniaeNA0.250.5FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
554EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACefpodoximeStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
555EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACeftarolineStreptococcus pneumoniaeNA0.250.25FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
556EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACeftarolineStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
557EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACeftobiproleStreptococcus pneumoniaeNA0.50.5FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
558EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACeftobiproleStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
559EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACeftriaxoneStreptococcus pneumoniaeNA0.52FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
560EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACeftriaxoneStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
561EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACefuroxime ivStreptococcus pneumoniaeNA0.51FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
562EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACefuroxime ivStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
563EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNACefuroxime oralStreptococcus pneumoniaeNA0.250.5FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
564EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNACefuroxime oralStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
565EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAErtapenemStreptococcus pneumoniaeNA0.50.5FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
566EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAErtapenemStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
567EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAImipenemStreptococcus pneumoniaeNA22FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
568EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAImipenemStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
569EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAMeropenem (indications other than meningitis)Streptococcus pneumoniaeNA22FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
570EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAMeropenem (indications other than meningitis)Streptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation.S.pneumoniae
571EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAMeropenem(meningitis)Streptococcus pneumoniaeNA0.250.25FALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [B] For use in meningitis determine the meropenem MIC.S.pneumoniae
572EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAMeropenem(meningitis)Streptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[A] The oxacillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥20 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note” can be reported susceptible without further testing. When the screen is positive (inhibition zone <20 mm), see flow chart below for interpretation. | [B] For use in meningitis determine the meropenem MIC.S.pneumoniae
573EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAMeropenem-vaborbactamStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
574EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAMeropenem-vaborbactamStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
575EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNALevofloxacinStreptococcus pneumoniaeNA22FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteS.pneumoniae
576EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNALevofloxacinStreptococcus pneumoniae5 mcg1616FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteS.pneumoniae
577EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAMoxifloxacinStreptococcus pneumoniaeNA0.50.5FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteS.pneumoniae
578EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAMoxifloxacinStreptococcus pneumoniae5 mcg2222FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteS.pneumoniae
579EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNANorfloxacin (screen)Streptococcus pneumoniae10 mcg10NoteFALSEFALSEFALSE[B] | [B] Isolates categorised as susceptible to norfloxacin can be reported susceptible to levofloxacin and moxifloxacin. Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.S.pneumoniae
580EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNADalbavancinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
581EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNADalbavancinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
582EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAOritavancinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
583EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAOritavancinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
584EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATeicoplaninStreptococcus pneumoniaeNA22FALSEFALSEFALSE[A] Non-wild typeisolates were not available when developing the disk diffusion method.S.pneumoniae
585EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATeicoplaninStreptococcus pneumoniae30 mcg1717FALSEFALSEFALSE[A] Non-wild typeisolates were not available when developing the disk diffusion method.S.pneumoniae
586EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATelavancinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
587EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATelavancinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
588EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAVancomycinStreptococcus pneumoniaeNA22FALSEFALSEFALSE[A] Non-wild typeisolates were not available when developing the disk diffusion method.S.pneumoniae
589EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAVancomycinStreptococcus pneumoniae5 mcg1616FALSEFALSEFALSE[A] Non-wild typeisolates were not available when developing the disk diffusion method.S.pneumoniae
590EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAAzithromycinStreptococcus pneumoniaeNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
591EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAAzithromycinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
592EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAClarithromycinStreptococcus pneumoniaeNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
593EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAClarithromycinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
594EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAErythromycinStreptococcus pneumoniaeNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
595EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAErythromycinStreptococcus pneumoniae15 mcg2219FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
596EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNARoxithromycinStreptococcus pneumoniaeNA0.51FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
597EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNARoxithromycinStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.S.pneumoniae
598EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATelithromycinStreptococcus pneumoniaeNA0.250.5FALSEFALSEFALSENAS.pneumoniae
599EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATelithromycinStreptococcus pneumoniae15 mcg2320FALSEFALSEFALSENAS.pneumoniae
600EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAClindamycinStreptococcus pneumoniaeNA0.50.5FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-16 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.S.pneumoniae
601EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAClindamycinStreptococcus pneumoniae2 mcg1919FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-16 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.S.pneumoniae
602EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNADoxycyclineStreptococcus pneumoniaeNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.S.pneumoniae
603EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNADoxycyclineStreptococcus pneumoniaeNANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.S.pneumoniae
604EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAEravacyclineStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
605EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAEravacyclineStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
606EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAMinocyclineStreptococcus pneumoniaeNA0.51FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.S.pneumoniae
607EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAMinocyclineStreptococcus pneumoniae30 mcg2421FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.S.pneumoniae
608EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATetracyclineStreptococcus pneumoniaeNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.S.pneumoniae
609EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATetracyclineStreptococcus pneumoniae30 mcg2522FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.S.pneumoniae
610EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATigecyclineStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
611EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATigecyclineStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
612EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNALinezolidStreptococcus pneumoniaeNA24FALSEFALSEFALSENAS.pneumoniae
613EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNALinezolidStreptococcus pneumoniae10 mcg2219FALSEFALSEFALSENAS.pneumoniae
614EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATedizolidStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
615EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATedizolidStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
616EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAChloramphenicolStreptococcus pneumoniaeNA88FALSEFALSEFALSENAS.pneumoniae
617EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAChloramphenicolStreptococcus pneumoniae30 mcg2121FALSEFALSEFALSENAS.pneumoniae
618EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNADaptomycinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
619EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNADaptomycinStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
620EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNAFosfomycin ivStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
621EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNAFosfomycin ivStreptococcus pneumoniaeNAIEIEFALSEFALSEFALSENAS.pneumoniae
622EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNARifampicinStreptococcus pneumoniaeNA0.060.5FALSEFALSEFALSENAS.pneumoniae
623EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNARifampicinStreptococcus pneumoniae5 mcg2217FALSEFALSEFALSENAS.pneumoniae
624EUCAST 20199.0humanhumanMICNAStreptococcus pneumoniaeNATrimethoprim-sulfamethoxazoleStreptococcus pneumoniaeNA12FALSEFALSEFALSENAS.pneumoniae
625EUCAST 20199.0humanhumanDISKNAStreptococcus pneumoniaeNATrimethoprim-sulfamethoxazoleStreptococcus pneumoniae1.25/23.75 mcg1310FALSEFALSEFALSENAS.pneumoniae
626EUCAST 20199.0humanhumanMICNAViridans group streptococciNABenzylpenicillinViridans group streptococciNA0.252FALSEFALSEFALSENAViridans group streptococci
627EUCAST 20199.0humanhumanDISKNAViridans group streptococciNABenzylpenicillinViridans group streptococci1 unit1812FALSEFALSEFALSENAViridans group streptococci
628EUCAST 20199.0humanhumanDISKNAViridans group streptococciNABenzylpenicillin (screen)Viridans group streptococci1 unit18NoteFALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
629EUCAST 20199.0humanhumanMICNAViridans group streptococciNAAmpicillinViridans group streptococciNA0.52FALSEFALSEFALSENAViridans group streptococci
630EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAAmpicillinViridans group streptococci2 mcg2115FALSEFALSEFALSENAViridans group streptococci
631EUCAST 20199.0humanhumanMICNAViridans group streptococciNAAmpicillin-sulbactamViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
632EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAAmpicillin-sulbactamViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
633EUCAST 20199.0humanhumanMICNAViridans group streptococciNAAmoxicillinViridans group streptococciNA0.52FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents. | [B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin.Viridans group streptococci
634EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAAmoxicillinViridans group streptococciNANoteNoteFALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents. | [B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin.Viridans group streptococci
635EUCAST 20199.0humanhumanMICNAViridans group streptococciNAAmoxicillin-clavulanic acidViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
636EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAAmoxicillin-clavulanic acidViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
637EUCAST 20199.0humanhumanMICNAViridans group streptococciNAPiperacillinViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
638EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAPiperacillinViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
639EUCAST 20199.0humanhumanMICNAViridans group streptococciNAPiperacillin-tazobactamViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
640EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAPiperacillin-tazobactamViridans group streptococciNANoteNoteFALSEFALSEFALSE[1/B] For isolates susceptible to benzylpenicillin, susceptibility can be inferred from benzylpenicillin or ampicillin. For isolates resistant to benzylpenicillin, susceptibility is inferred from ampicillin. | [A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. Isolates categorised as susceptible can be reported susceptible to beta-lactam agents for which clinical breakpoints are listed (including those with “Note”). Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Viridans group streptococci
641EUCAST 20199.0humanhumanMICNAViridans group streptococciNATicarcillinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
642EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATicarcillinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
643EUCAST 20199.0humanhumanMICNAViridans group streptococciNATicarcillin-clavulanic acidViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
644EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATicarcillin-clavulanic acidViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
645EUCAST 20199.0humanhumanMICNAViridans group streptococciNAPhenoxymethylpenicillinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
646EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAPhenoxymethylpenicillinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
647EUCAST 20199.0humanhumanMICNAViridans group streptococciNACefazolinViridans group streptococciNA0.50.5FALSEFALSEFALSENAViridans group streptococci
648EUCAST 20199.0humanhumanDISKNAViridans group streptococciNACefazolinViridans group streptococci30 mcgIPIPFALSEFALSEFALSENAViridans group streptococci
649EUCAST 20199.0humanhumanMICNAViridans group streptococciNACefepimeViridans group streptococciNA0.50.5FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
650EUCAST 20199.0humanhumanDISKNAViridans group streptococciNACefepimeViridans group streptococci30 mcg2525FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
651EUCAST 20199.0humanhumanMICNAViridans group streptococciNACefotaximeViridans group streptococciNA0.50.5FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
652EUCAST 20199.0humanhumanDISKNAViridans group streptococciNACefotaximeViridans group streptococci5 mcg2323FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
653EUCAST 20199.0humanhumanMICNAViridans group streptococciNACeftolozane-tazobactam, S. anginosus groupViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
654EUCAST 20199.0humanhumanDISKNAViridans group streptococciNACeftolozane-tazobactam, S. anginosus groupViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
655EUCAST 20199.0humanhumanMICNAViridans group streptococciNACeftriaxoneViridans group streptococciNA0.50.5FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
656EUCAST 20199.0humanhumanDISKNAViridans group streptococciNACeftriaxoneViridans group streptococci30 mcg2727FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
657EUCAST 20199.0humanhumanMICNAViridans group streptococciNACefuroxime ivViridans group streptococciNA0.50.5FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
658EUCAST 20199.0humanhumanDISKNAViridans group streptococciNACefuroxime ivViridans group streptococci30 mcg2626FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
659EUCAST 20199.0humanhumanMICNAViridans group streptococciNAErtapenemViridans group streptococciNA0.50.5FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
660EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAErtapenemViridans group streptococciNANoteNoteFALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
661EUCAST 20199.0humanhumanMICNAViridans group streptococciNAImipenemViridans group streptococciNA22FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
662EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAImipenemViridans group streptococciNANoteNoteFALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
663EUCAST 20199.0humanhumanMICNAViridans group streptococciNAMeropenemViridans group streptococciNA22FALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
664EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAMeropenemViridans group streptococciNANoteNoteFALSEFALSEFALSE[A] Benzylpenicillin 1 unit can be used to screen for beta-lactam resistance in viridans group streptococci. See Note A on penicillins.Viridans group streptococci
665EUCAST 20199.0humanhumanMICNAViridans group streptococciNAMeropenem-vaborbactamViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
666EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAMeropenem-vaborbactamViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
667EUCAST 20199.0humanhumanMICNAViridans group streptococciNALevofloxacinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
668EUCAST 20199.0humanhumanDISKNAViridans group streptococciNALevofloxacinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
669EUCAST 20199.0humanhumanMICNAViridans group streptococciNAMoxifloxacinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
670EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAMoxifloxacinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
671EUCAST 20199.0humanhumanMICNAViridans group streptococciNAAmikacinViridans group streptococciNANoteNoteFALSEFALSEFALSENAViridans group streptococci
672EUCAST 20199.0humanhumanMICNAViridans group streptococciNAGentamicin (test for high-level aminoglycoside resistance)Viridans group streptococciNANoteNoteFALSEFALSEFALSENAViridans group streptococci
673EUCAST 20199.0humanhumanMICNAViridans group streptococciNANetilmicinViridans group streptococciNANoteNoteFALSEFALSEFALSENAViridans group streptococci
674EUCAST 20199.0humanhumanMICNAViridans group streptococciNATobramycinViridans group streptococciNANoteNoteFALSEFALSEFALSENAViridans group streptococci
675EUCAST 20199.0humanhumanMICNAViridans group streptococciNADalbavancin, S. anginosus groupViridans group streptococciNA0.1250.125FALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Viridans group streptococci
676EUCAST 20199.0humanhumanDISKNAViridans group streptococciNADalbavancin, S. anginosus groupViridans group streptococciNANoteNoteFALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Viridans group streptococci
677EUCAST 20199.0humanhumanMICNAViridans group streptococciNAOritavancin, S. anginosus groupViridans group streptococciNA0.250.25FALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Viridans group streptococci
678EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAOritavancin, S. anginosus groupViridans group streptococciNANoteNoteFALSEFALSEFALSE[2] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [3] Isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion criteria have not been defined and an MIC method should be used.Viridans group streptococci
679EUCAST 20199.0humanhumanMICNAViridans group streptococciNATeicoplaninViridans group streptococciNA22FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Viridans group streptococci
680EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATeicoplaninViridans group streptococci30 mcg1616FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Viridans group streptococci
681EUCAST 20199.0humanhumanMICNAViridans group streptococciNATelavancinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
682EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATelavancinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
683EUCAST 20199.0humanhumanMICNAViridans group streptococciNAVancomycinViridans group streptococciNA22FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Viridans group streptococci
684EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAVancomycinViridans group streptococci5 mcg1515FALSEFALSEFALSE[B] Non-wild type isolates were not available when developing the disk diffusion method.Viridans group streptococci
685EUCAST 20199.0humanhumanMICNAViridans group streptococciNAAzithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
686EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAAzithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
687EUCAST 20199.0humanhumanMICNAViridans group streptococciNAClarithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
688EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAClarithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
689EUCAST 20199.0humanhumanMICNAViridans group streptococciNAErythromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
690EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAErythromycinViridans group streptococci15 mcgIEIEFALSEFALSEFALSENAViridans group streptococci
691EUCAST 20199.0humanhumanMICNAViridans group streptococciNARoxithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
692EUCAST 20199.0humanhumanDISKNAViridans group streptococciNARoxithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
693EUCAST 20199.0humanhumanMICNAViridans group streptococciNATelithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
694EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATelithromycinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
695EUCAST 20199.0humanhumanMICNAViridans group streptococciNAClindamycinViridans group streptococciNA0.50.5FALSEFALSEFALSE[A] Place the erythromycin and clindamycin disks 12-16 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Viridans group streptococci
696EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAClindamycinViridans group streptococci2 mcg1919FALSEFALSEFALSE[A] Place the erythromycin and clindamycin disks 12-16 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Viridans group streptococci
697EUCAST 20199.0humanhumanMICNAViridans group streptococciNAQuinupristin-dalfopristinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
698EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAQuinupristin-dalfopristinViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
699EUCAST 20199.0humanhumanMICNAViridans group streptococciNAEravacyclineViridans group streptococciNA0.1250.125FALSEFALSEFALSENAViridans group streptococci
700EUCAST 20199.0humanhumanDISKNAViridans group streptococciNAEravacyclineViridans group streptococciIP mcgIPIPFALSEFALSEFALSENAViridans group streptococci
701EUCAST 20199.0humanhumanMICNAViridans group streptococciNATigecyclineViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
702EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATigecyclineViridans group streptococciNAIEIEFALSEFALSEFALSENAViridans group streptococci
703EUCAST 20199.0humanhumanMICNAViridans group streptococciNATedizolid, S. anginosus groupViridans group streptococciNA0.250.25FALSEFALSEFALSE[A] Perform an MIC test.Viridans group streptococci
704EUCAST 20199.0humanhumanDISKNAViridans group streptococciNATedizolid, S. anginosus groupViridans group streptococciNANoteNoteFALSEFALSEFALSE[A] Perform an MIC test.Viridans group streptococci
705EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNABenzylpenicillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
706EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNABenzylpenicillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
707EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNABenzylpenicillin (screen)Haemophilus influenzae1 unit12NoteFALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
708EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmpicillinHaemophilus influenzaeNA11FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
709EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmpicillinHaemophilus influenzae2 mcg1616FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
710EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmpicillin-sulbactamHaemophilus influenzaeNA11FALSEFALSEFALSE[4/C] Susceptibility can be inferred from amoxicillin-clavulanic acid. | [3] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
711EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmpicillin-sulbactamHaemophilus influenzae10/10 mcgNoteNoteFALSEFALSEFALSE[4/C] Susceptibility can be inferred from amoxicillin-clavulanic acid. | [3] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
712EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmoxicillin ivHaemophilus influenzaeNA22FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [D] Susceptibility can be inferred from ampicillin.H.influenzae
713EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmoxicillin ivHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [D] Susceptibility can be inferred from ampicillin.H.influenzae
714EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmoxicillin oralHaemophilus influenzaeNA22FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [D] Susceptibility can be inferred from ampicillin.H.influenzae
715EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmoxicillin oralHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [D] Susceptibility can be inferred from ampicillin.H.influenzae
716EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmoxicillin-clavulanic acid ivHaemophilus influenzaeNA22FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
717EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmoxicillin-clavulanic acid ivHaemophilus influenzae2/1 mcg1515FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
718EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmoxicillin-clavulanic acid oralHaemophilus influenzaeNA22FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
719EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmoxicillin-clavulanic acid oralHaemophilus influenzae2/1 mcg1515FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
720EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAPiperacillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
721EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAPiperacillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
722EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAPiperacillin-tazobactamHaemophilus influenzaeNA0.250.25FALSEFALSEFALSE[6] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
723EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAPiperacillin-tazobactamHaemophilus influenzae30/6 mcg2727FALSEFALSEFALSE[6] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L. | [A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
724EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATicarcillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
725EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATicarcillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
726EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATicarcillin-clavulanic acidHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
727EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATicarcillin-clavulanic acidHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
728EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATemocillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
729EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATemocillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
730EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAPhenoxymethylpenicillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
731EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAPhenoxymethylpenicillinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
732EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACefepimeHaemophilus influenzaeNA0.250.25FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [B] ATU relevant only if the benzylpenicillin 1 unit disk screen is positive (inhibition zone <12 mm).H.influenzae
733EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACefepimeHaemophilus influenzae30 mcg2828FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [B] ATU relevant only if the benzylpenicillin 1 unit disk screen is positive (inhibition zone <12 mm).H.influenzae
734EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACefiximeHaemophilus influenzaeNA0.1250.125FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
735EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACefiximeHaemophilus influenzae5 mcg2626FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
736EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACefotaximeHaemophilus influenzaeNA0.1250.125FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
737EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACefotaximeHaemophilus influenzae5 mcg2727FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
738EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACefpodoximeHaemophilus influenzaeNA0.250.25FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [B] ATU relevant only if the benzylpenicillin 1 unit disk screen is positive (inhibition zone <12 mm).H.influenzae
739EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACefpodoximeHaemophilus influenzae10 mcg2626FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [B] ATU relevant only if the benzylpenicillin 1 unit disk screen is positive (inhibition zone <12 mm).H.influenzae
740EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACeftarolineHaemophilus influenzaeNA0.030.03FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
741EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACeftarolineHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
742EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACeftibutenHaemophilus influenzaeNA11FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
743EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACeftibutenHaemophilus influenzae30 mcg2525FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
744EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACeftobiproleHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
745EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACeftobiproleHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
746EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACeftolozane-tazobactamHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
747EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACeftolozane-tazobactamHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
748EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACeftriaxoneHaemophilus influenzaeNA0.1250.125FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
749EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACeftriaxoneHaemophilus influenzae30 mcg3232FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
750EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACefuroxime ivHaemophilus influenzaeNA12FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
751EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACefuroxime ivHaemophilus influenzae30 mcg2725FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
752EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACefuroxime oralHaemophilus influenzaeNA0.1251FALSEFALSEFALSENAH.influenzae
753EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACefuroxime oralHaemophilus influenzae30 mcg5027FALSEFALSEFALSENAH.influenzae
754EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAErtapenemHaemophilus influenzaeNA0.50.5FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
755EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAErtapenemHaemophilus influenzae10 mcg2323FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
756EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAImipenemHaemophilus influenzaeNA22FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [B] ATU relevant only if the benzylpenicillin 1 unit disk screen is positive (inhibition zone <12 mm).H.influenzae
757EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAImipenemHaemophilus influenzae10 mcg2020FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation. | [B] ATU relevant only if the benzylpenicillin 1 unit disk screen is positive (inhibition zone <12 mm).H.influenzae
758EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAMeropenem (indications other than meningitis)Haemophilus influenzaeNA22FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
759EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAMeropenem (indications other than meningitis)Haemophilus influenzae10 mcg2020FALSEFALSEFALSE[A] The benzylpenicillin 1 unit disk screen test shall be used to exclude beta-lactam resistance mechanisms. When the screen is negative (inhibition zone ≥12 mm) all beta-lactam agents for which clinical breakpoints are available, including those with “Note”, can be reported susceptible without further testing. When the screen is positive (inhibition zone <12 mm), see flow chart below for interpretation.H.influenzae
760EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAMeropenem(meningitis)Haemophilus influenzaeNA0.250.25FALSEFALSEFALSE[C] For use in meningitis determine the meropenem MIC value.H.influenzae
761EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAMeropenem(meningitis)Haemophilus influenzaeNANoteNoteFALSEFALSEFALSE[C] For use in meningitis determine the meropenem MIC value.H.influenzae
762EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAMeropenem-vaborbactamHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
763EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAMeropenem-vaborbactamHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
764EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAztreonamHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
765EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAztreonamHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
766EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNACiprofloxacinHaemophilus influenzaeNA0.060.06FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
767EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNACiprofloxacinHaemophilus influenzae5 mcg3030FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
768EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNALevofloxacinHaemophilus influenzaeNA0.060.06FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
769EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNALevofloxacinHaemophilus influenzae5 mcg3030FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
770EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAMoxifloxacinHaemophilus influenzaeNA0.1250.125FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
771EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAMoxifloxacinHaemophilus influenzae5 mcg2828FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
772EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNANalidixic acid (screen)Haemophilus influenzae30 mcg23NoteFALSEFALSEFALSE[B] | [B] Isolates categorised as susceptible to nalidixic acid can be reported susceptible to ciprofloxacin, levofloxacin, moxifloxacin and ofloxacin. Isolates categorised as non-susceptible may have fluoroquinolone resistance and should be tested against the appropriate agent.H.influenzae
773EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAOfloxacinHaemophilus influenzaeNA0.060.06FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
774EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAOfloxacinHaemophilus influenzae5 mcg3030FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteH.influenzae
775EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAmikacinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
776EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAmikacinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
777EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAGentamicinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
778EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAGentamicinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
779EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNANetilmicinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
780EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNANetilmicinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
781EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATobramycinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
782EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATobramycinHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
783EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAAzithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
784EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAAzithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
785EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAClarithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
786EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAClarithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
787EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAErythromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
788EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAErythromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
789EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNARoxithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
790EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNARoxithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
791EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATelithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
792EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATelithromycinHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Clinical evidence for the efficacy of macrolides in H. influenzae respiratory infections is conflicting due to high spontaneous cure rates. Should there be a need to test any macrolide against this species, the epidemiological cut-offs (ECOFFs) should be used to detect strains with acquired resistance. The ECOFFs for each agent are: azithromycin 4 mg/L, clarithromycin 32 mg/L, erythromycin 16 mg/L and telithromycin 8 mg/L. There are insufficient data available to establish an ECOFF for roxithromycin.H.influenzae
793EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNADoxycyclineHaemophilus influenzaeNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.H.influenzae
794EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNADoxycyclineHaemophilus influenzaeNANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.H.influenzae
795EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAEravacyclineHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
796EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAEravacyclineHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
797EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAMinocyclineHaemophilus influenzaeNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.H.influenzae
798EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAMinocyclineHaemophilus influenzae30 mcg2421FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.H.influenzae
799EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATetracyclineHaemophilus influenzaeNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.H.influenzae
800EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATetracyclineHaemophilus influenzae30 mcg2522FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.H.influenzae
801EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATigecyclineHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
802EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATigecyclineHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
803EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAChloramphenicolHaemophilus influenzaeNA22FALSEFALSEFALSENAH.influenzae
804EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAChloramphenicolHaemophilus influenzae30 mcg2828FALSEFALSEFALSENAH.influenzae
805EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNAFosfomycin ivHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
806EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNAFosfomycin ivHaemophilus influenzaeNAIEIEFALSEFALSEFALSENAH.influenzae
807EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNARifampicin (for prophylaxis only)Haemophilus influenzaeNA11FALSEFALSEFALSENAH.influenzae
808EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNARifampicin (for prophylaxis only)Haemophilus influenzae5 mcg1818FALSEFALSEFALSENAH.influenzae
809EUCAST 20199.0humanhumanMICNAHaemophilus influenzaeNATrimethoprim-sulfamethoxazoleHaemophilus influenzaeNA0.51FALSEFALSEFALSENAH.influenzae
810EUCAST 20199.0humanhumanDISKNAHaemophilus influenzaeNATrimethoprim-sulfamethoxazoleHaemophilus influenzae1.25/23.75 mcg2320FALSEFALSEFALSENAH.influenzae
811EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAAmpicillin-sulbactamMoraxella catarrhalisNA11FALSEFALSEFALSE[3/A] Susceptibility can be inferred from amoxicillin-clavulanic acid. | [2] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L.M.catarrhalis
812EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAAmpicillin-sulbactamMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[3/A] Susceptibility can be inferred from amoxicillin-clavulanic acid. | [2] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L.M.catarrhalis
813EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAAmoxicillin-clavulanic acidMoraxella catarrhalisNA11FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.M.catarrhalis
814EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAAmoxicillin-clavulanic acidMoraxella catarrhalis2/1 mcg1919FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.M.catarrhalis
815EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAPiperacillin-tazobactamMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[3/A] Susceptibility can be inferred from amoxicillin-clavulanic acid.M.catarrhalis
816EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAPiperacillin-tazobactamMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[3/A] Susceptibility can be inferred from amoxicillin-clavulanic acid.M.catarrhalis
817EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATicarcillinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
818EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATicarcillinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
819EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATicarcillin-clavulanic acidMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
820EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATicarcillin-clavulanic acidMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
821EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATemocillinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
822EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATemocillinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
823EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACefepimeMoraxella catarrhalisNA44FALSEFALSEFALSENAM.catarrhalis
824EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACefepimeMoraxella catarrhalis30 mcg2020FALSEFALSEFALSENAM.catarrhalis
825EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACefiximeMoraxella catarrhalisNA0.51FALSEFALSEFALSENAM.catarrhalis
826EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACefiximeMoraxella catarrhalis5 mcg2118FALSEFALSEFALSENAM.catarrhalis
827EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACefotaximeMoraxella catarrhalisNA12FALSEFALSEFALSENAM.catarrhalis
828EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACefotaximeMoraxella catarrhalis5 mcg2017FALSEFALSEFALSENAM.catarrhalis
829EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACefpodoximeMoraxella catarrhalisNAIPIPFALSEFALSEFALSENAM.catarrhalis
830EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACefpodoximeMoraxella catarrhalis10 mcgIPIPFALSEFALSEFALSENAM.catarrhalis
831EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACeftarolineMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
832EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACeftarolineMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
833EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACeftibutenMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
834EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACeftibutenMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
835EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACeftobiproleMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
836EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACeftobiproleMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
837EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACeftolozane-tazobactamMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
838EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACeftolozane-tazobactamMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
839EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACeftriaxoneMoraxella catarrhalisNA12FALSEFALSEFALSENAM.catarrhalis
840EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACeftriaxoneMoraxella catarrhalis30 mcg2421FALSEFALSEFALSENAM.catarrhalis
841EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACefuroxime ivMoraxella catarrhalisNA48FALSEFALSEFALSENAM.catarrhalis
842EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACefuroxime ivMoraxella catarrhalis30 mcg2118FALSEFALSEFALSENAM.catarrhalis
843EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACefuroxime oralMoraxella catarrhalisNA0.1254FALSEFALSEFALSENAM.catarrhalis
844EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACefuroxime oralMoraxella catarrhalis30 mcg5021FALSEFALSEFALSENAM.catarrhalis
845EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAErtapenemMoraxella catarrhalisNA0.50.5FALSEFALSEFALSENAM.catarrhalis
846EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAErtapenemMoraxella catarrhalis10 mcg2929FALSEFALSEFALSENAM.catarrhalis
847EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAImipenemMoraxella catarrhalisNA22FALSEFALSEFALSENAM.catarrhalis
848EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAImipenemMoraxella catarrhalis10 mcg2929FALSEFALSEFALSENAM.catarrhalis
849EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAMeropenemMoraxella catarrhalisNA22FALSEFALSEFALSENAM.catarrhalis
850EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAMeropenemMoraxella catarrhalis10 mcg3333FALSEFALSEFALSENAM.catarrhalis
851EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAMeropenem-vaborbactamMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
852EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAMeropenem-vaborbactamMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
853EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAAztreonamMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
854EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAAztreonamMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
855EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNACiprofloxacinMoraxella catarrhalisNA0.1250.125FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
856EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNACiprofloxacinMoraxella catarrhalis5 mcg3131FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
857EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNALevofloxacinMoraxella catarrhalisNA0.1250.125FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
858EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNALevofloxacinMoraxella catarrhalis5 mcg2929FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
859EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAMoxifloxacinMoraxella catarrhalisNA0.250.25FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
860EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAMoxifloxacinMoraxella catarrhalis5 mcg2626FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
861EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNANalidixic acid (screen)Moraxella catarrhalis30 mcg23NoteFALSEFALSEFALSE[B] | [B] Isolates categorised as susceptible to nalidixic acid can be reported susceptible to ciprofloxacin, levofloxacin, moxifloxacin and ofloxacin. Isolates categorised as non-susceptible may have fluoroquinolone resistance and should be tested against the appropriate agent.M.catarrhalis
862EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAOfloxacinMoraxella catarrhalisNA0.250.25FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
863EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAOfloxacinMoraxella catarrhalis5 mcg2828FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteM.catarrhalis
864EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAAmikacinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
865EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAAmikacinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
866EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAGentamicinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
867EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAGentamicinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
868EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNANetilmicinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
869EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNANetilmicinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
870EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATobramycinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
871EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATobramycinMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
872EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAAzithromycinMoraxella catarrhalisNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
873EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAAzithromycinMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
874EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAClarithromycinMoraxella catarrhalisNA0.250.5FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
875EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAClarithromycinMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
876EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAErythromycinMoraxella catarrhalisNA0.250.5FALSEFALSEFALSE[A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
877EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAErythromycinMoraxella catarrhalis15 mcg2320FALSEFALSEFALSE[A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
878EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNARoxithromycinMoraxella catarrhalisNA0.51FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
879EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNARoxithromycinMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.M.catarrhalis
880EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATelithromycinMoraxella catarrhalisNA0.250.5FALSEFALSEFALSENAM.catarrhalis
881EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATelithromycinMoraxella catarrhalis15 mcg2320FALSEFALSEFALSENAM.catarrhalis
882EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNADoxycyclineMoraxella catarrhalisNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.M.catarrhalis
883EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNADoxycyclineMoraxella catarrhalisNANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.M.catarrhalis
884EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAEravacyclineMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
885EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAEravacyclineMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
886EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAMinocyclineMoraxella catarrhalisNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.M.catarrhalis
887EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAMinocyclineMoraxella catarrhalis30 mcg2522FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.M.catarrhalis
888EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATetracyclineMoraxella catarrhalisNA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.M.catarrhalis
889EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATetracyclineMoraxella catarrhalis30 mcg2825FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.M.catarrhalis
890EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATigecyclineMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
891EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATigecyclineMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
892EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAChloramphenicolMoraxella catarrhalisNA22FALSEFALSEFALSE[1/A] Breakpoints relate to topical use only.M.catarrhalis
893EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAChloramphenicolMoraxella catarrhalis30 mcg3030FALSEFALSEFALSE[1/A] Breakpoints relate to topical use only.M.catarrhalis
894EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNAFosfomycin ivMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
895EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNAFosfomycin ivMoraxella catarrhalisNAIEIEFALSEFALSEFALSENAM.catarrhalis
896EUCAST 20199.0humanhumanMICNAMoraxella catarrhalisNATrimethoprim-sulfamethoxazoleMoraxella catarrhalisNA0.51FALSEFALSEFALSENAM.catarrhalis
897EUCAST 20199.0humanhumanDISKNAMoraxella catarrhalisNATrimethoprim-sulfamethoxazoleMoraxella catarrhalis1.25/23.75 mcg1815FALSEFALSEFALSENAM.catarrhalis
898NANAhumanhumanMICNANeisseria gonorrhoeaeNABenzylpenicillinNeisseria gonorrhoeaeNA0.061FALSEFALSEFALSENAN.gonorrhoeae
899NANAhumanhumanMICNANeisseria gonorrhoeaeNAAmpicillinNeisseria gonorrhoeaeNANoteNoteFALSEFALSEFALSENAN.gonorrhoeae
900NANAhumanhumanMICNANeisseria gonorrhoeaeNAAmpicillin-sulbactamNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
901NANAhumanhumanMICNANeisseria gonorrhoeaeNAAmoxicillinNeisseria gonorrhoeaeNANoteNoteFALSEFALSEFALSENAN.gonorrhoeae
902NANAhumanhumanMICNANeisseria gonorrhoeaeNAAmoxicillin-clavulanic acidNeisseria gonorrhoeaeNANoteNoteFALSEFALSEFALSENAN.gonorrhoeae
903NANAhumanhumanMICNANeisseria gonorrhoeaeNATemocillinNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
904NANAhumanhumanMICNANeisseria gonorrhoeaeNACefiximeNeisseria gonorrhoeaeNA0.1250.125FALSEFALSEFALSENAN.gonorrhoeae
905NANAhumanhumanMICNANeisseria gonorrhoeaeNACefotaximeNeisseria gonorrhoeaeNA0.1250.125FALSEFALSEFALSENAN.gonorrhoeae
906NANAhumanhumanMICNANeisseria gonorrhoeaeNACeftriaxoneNeisseria gonorrhoeaeNA0.1250.125FALSEFALSEFALSENAN.gonorrhoeae
907NANAhumanhumanMICNANeisseria gonorrhoeaeNAErtapenemNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
908NANAhumanhumanMICNANeisseria gonorrhoeaeNAImipenemNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
909NANAhumanhumanMICNANeisseria gonorrhoeaeNAMeropenemNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
910NANAhumanhumanMICNANeisseria gonorrhoeaeNAMeropenem-vaborbactamNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
911NANAhumanhumanMICNANeisseria gonorrhoeaeNAAztreonamNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
912NANAhumanhumanMICNANeisseria gonorrhoeaeNACiprofloxacinNeisseria gonorrhoeaeNA0.030.06FALSEFALSEFALSENAN.gonorrhoeae
913NANAhumanhumanMICNANeisseria gonorrhoeaeNALevofloxacinNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
914NANAhumanhumanMICNANeisseria gonorrhoeaeNAMoxifloxacinNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
915NANAhumanhumanMICNANeisseria gonorrhoeaeNAOfloxacinNeisseria gonorrhoeaeNA0.1250.25FALSEFALSEFALSENAN.gonorrhoeae
916NANAhumanhumanMICNANeisseria gonorrhoeaeNAAzithromycinNeisseria gonorrhoeaeNANoteNoteFALSEFALSEFALSENAN.gonorrhoeae
917NANAhumanhumanMICNANeisseria gonorrhoeaeNADoxycyclineNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
918NANAhumanhumanMICNANeisseria gonorrhoeaeNAEravacyclineNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
919NANAhumanhumanMICNANeisseria gonorrhoeaeNAMinocyclineNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
920NANAhumanhumanMICNANeisseria gonorrhoeaeNATetracyclineNeisseria gonorrhoeaeNA0.51FALSEFALSEFALSENAN.gonorrhoeae
921NANAhumanhumanMICNANeisseria gonorrhoeaeNATigecyclineNeisseria gonorrhoeaeNAIEIEFALSEFALSEFALSENAN.gonorrhoeae
922NANAhumanhumanMICNANeisseria gonorrhoeaeNASpectinomycinNeisseria gonorrhoeaeNA6464FALSEFALSEFALSENAN.gonorrhoeae
923NANAhumanhumanMICNANeisseria meningitidisNABenzylpenicillinNeisseria meningitidisNA0.060.25FALSEFALSEFALSENAN.meningitidis
924NANAhumanhumanMICNANeisseria meningitidisNAAmpicillinNeisseria meningitidisNA0.1251FALSEFALSEFALSENAN.meningitidis
925NANAhumanhumanMICNANeisseria meningitidisNAAmpicillin-sulbactamNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
926NANAhumanhumanMICNANeisseria meningitidisNAAmoxicillinNeisseria meningitidisNA0.1251FALSEFALSEFALSENAN.meningitidis
927NANAhumanhumanMICNANeisseria meningitidisNACefotaximeNeisseria meningitidisNA0.1250.125FALSEFALSEFALSENAN.meningitidis
928NANAhumanhumanMICNANeisseria meningitidisNACeftriaxoneNeisseria meningitidisNA0.1250.125FALSEFALSEFALSENAN.meningitidis
929NANAhumanhumanMICNANeisseria meningitidisNAMeropenem(meningitis)Neisseria meningitidisNA0.250.25FALSEFALSEFALSENAN.meningitidis
930NANAhumanhumanMICNANeisseria meningitidisNAMeropenem-vaborbactamNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
931NANAhumanhumanMICNANeisseria meningitidisNACiprofloxacinNeisseria meningitidisNA0.030.03FALSEFALSEFALSENAN.meningitidis
932NANAhumanhumanMICNANeisseria meningitidisNALevofloxacinNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
933NANAhumanhumanMICNANeisseria meningitidisNAMoxifloxacinNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
934NANAhumanhumanMICNANeisseria meningitidisNAOfloxacinNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
935NANAhumanhumanMICNANeisseria meningitidisNAEravacyclineNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
936NANAhumanhumanMICNANeisseria meningitidisNAMinocyclineNeisseria meningitidisNA12FALSEFALSEFALSENAN.meningitidis
937NANAhumanhumanMICNANeisseria meningitidisNATetracyclineNeisseria meningitidisNA12FALSEFALSEFALSENAN.meningitidis
938NANAhumanhumanMICNANeisseria meningitidisNATigecyclineNeisseria meningitidisNAIEIEFALSEFALSEFALSENAN.meningitidis
939NANAhumanhumanMICNANeisseria meningitidisNAChloramphenicolNeisseria meningitidisNA22FALSEFALSEFALSENAN.meningitidis
940NANAhumanhumanMICNANeisseria meningitidisNARifampicinNeisseria meningitidisNA0.250.25FALSEFALSEFALSENAN.meningitidis
941EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNABenzylpenicillinGram-positive anaerobes except Clostridioides difficileNA0.250.5FALSEFALSEFALSENAAnaerobes, Grampositive
942EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAAmpicillinGram-positive anaerobes except Clostridioides difficileNA48FALSEFALSEFALSENAAnaerobes, Grampositive
943EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAAmpicillin-sulbactamGram-positive anaerobes except Clostridioides difficileNA48FALSEFALSEFALSENAAnaerobes, Grampositive
944EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAAmoxicillinGram-positive anaerobes except Clostridioides difficileNA48FALSEFALSEFALSENAAnaerobes, Grampositive
945EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAAmoxicillin-clavulanic acidGram-positive anaerobes except Clostridioides difficileNA48FALSEFALSEFALSENAAnaerobes, Grampositive
946EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAPiperacillinGram-positive anaerobes except Clostridioides difficileNA816FALSEFALSEFALSENAAnaerobes, Grampositive
947EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAPiperacillin-tazobactamGram-positive anaerobes except Clostridioides difficileNA816FALSEFALSEFALSENAAnaerobes, Grampositive
948EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNATicarcillinGram-positive anaerobes except Clostridioides difficileNA816FALSEFALSEFALSENAAnaerobes, Grampositive
949EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNATicarcillin-clavulanic acidGram-positive anaerobes except Clostridioides difficileNA816FALSEFALSEFALSENAAnaerobes, Grampositive
950EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAPhenoxymethylpenicillinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
951EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNACefoxitinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
952EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNACeftolozane-tazobactamGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
953EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAErtapenemGram-positive anaerobes except Clostridioides difficileNA0.50.5FALSEFALSEFALSENAAnaerobes, Grampositive
954EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAImipenemGram-positive anaerobes except Clostridioides difficileNA24FALSEFALSEFALSENAAnaerobes, Grampositive
955EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAMeropenemGram-positive anaerobes except Clostridioides difficileNA28FALSEFALSEFALSENAAnaerobes, Grampositive
956EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAMeropenem-vaborbactamGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
957EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAMoxifloxacinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
958EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNADalbavancinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
959EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAOritavancinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
960EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNATeicoplaninGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
961EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNATelavancinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
962EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAVancomycinGram-positive anaerobes except Clostridioides difficileNA22FALSEFALSEFALSENAAnaerobes, Grampositive
963EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAErythromycinGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
964EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAClindamycinGram-positive anaerobes except Clostridioides difficileNA44FALSEFALSEFALSENAAnaerobes, Grampositive
965EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNADoxycyclineGram-positive anaerobes except Clostridioides difficileNANoteNoteFALSEFALSEFALSENAAnaerobes, Grampositive
966EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAEravacyclineGram-positive anaerobes except Clostridioides difficileNAIEIEFALSEFALSEFALSENAAnaerobes, Grampositive
967EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAMinocyclineGram-positive anaerobes except Clostridioides difficileNANoteNoteFALSEFALSEFALSENAAnaerobes, Grampositive
968EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNATetracyclineGram-positive anaerobes except Clostridioides difficileNANoteNoteFALSEFALSEFALSENAAnaerobes, Grampositive
969EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNATigecyclineGram-positive anaerobes except Clostridioides difficileNANoteNoteFALSEFALSEFALSENAAnaerobes, Grampositive
970EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAChloramphenicolGram-positive anaerobes except Clostridioides difficileNA88FALSEFALSEFALSENAAnaerobes, Grampositive
971EUCAST 20199.0humanhumanMICNAGram-positive anaerobes except Clostridioides difficileNAMetronidazoleGram-positive anaerobes except Clostridioides difficileNA44FALSEFALSEFALSENAAnaerobes, Grampositive
972EUCAST 20199.0humanhumanMICNAClostridioides difficileNAVancomycinClostridioides difficileNA22FALSEFALSEFALSENAC.difficile
973EUCAST 20199.0humanhumanMICNAClostridioides difficileNAFidaxomicinClostridioides difficileNAIEIEFALSEFALSEFALSENAC.difficile
974EUCAST 20199.0humanhumanMICNAClostridioides difficileNAMetronidazoleClostridioides difficileNA22FALSEFALSEFALSENAC.difficile
975NANAhumanhumanMICNAGram-negative anaerobesNABenzylpenicillinGram-negative anaerobesNA0.250.5FALSEFALSEFALSENAAnaerobes, Gramnegative
976NANAhumanhumanMICNAGram-negative anaerobesNAAmpicillinGram-negative anaerobesNA0.52FALSEFALSEFALSENAAnaerobes, Gramnegative
977NANAhumanhumanMICNAGram-negative anaerobesNAAmpicillin-sulbactamGram-negative anaerobesNA48FALSEFALSEFALSENAAnaerobes, Gramnegative
978NANAhumanhumanMICNAGram-negative anaerobesNAAmoxicillinGram-negative anaerobesNA0.52FALSEFALSEFALSENAAnaerobes, Gramnegative
979NANAhumanhumanMICNAGram-negative anaerobesNAAmoxicillin-clavulanic acidGram-negative anaerobesNA48FALSEFALSEFALSENAAnaerobes, Gramnegative
980NANAhumanhumanMICNAGram-negative anaerobesNAPiperacillinGram-negative anaerobesNA1616FALSEFALSEFALSENAAnaerobes, Gramnegative
981NANAhumanhumanMICNAGram-negative anaerobesNAPiperacillin-tazobactamGram-negative anaerobesNA816FALSEFALSEFALSENAAnaerobes, Gramnegative
982NANAhumanhumanMICNAGram-negative anaerobesNATicarcillinGram-negative anaerobesNA1616FALSEFALSEFALSENAAnaerobes, Gramnegative
983NANAhumanhumanMICNAGram-negative anaerobesNATicarcillin-clavulanic acidGram-negative anaerobesNA816FALSEFALSEFALSENAAnaerobes, Gramnegative
984NANAhumanhumanMICNAGram-negative anaerobesNAPhenoxymethylpenicillinGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
985NANAhumanhumanMICNAGram-negative anaerobesNACefoxitinGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
986NANAhumanhumanMICNAGram-negative anaerobesNACeftolozane-tazobactamGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
987NANAhumanhumanMICNAGram-negative anaerobesNAErtapenemGram-negative anaerobesNA0.50.5FALSEFALSEFALSENAAnaerobes, Gramnegative
988NANAhumanhumanMICNAGram-negative anaerobesNAImipenemGram-negative anaerobesNA24FALSEFALSEFALSENAAnaerobes, Gramnegative
989NANAhumanhumanMICNAGram-negative anaerobesNAMeropenemGram-negative anaerobesNA28FALSEFALSEFALSENAAnaerobes, Gramnegative
990NANAhumanhumanMICNAGram-negative anaerobesNAMeropenem-vaborbactamGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
991NANAhumanhumanMICNAGram-negative anaerobesNAMoxifloxacinGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
992NANAhumanhumanMICNAGram-negative anaerobesNAErythromycinGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
993NANAhumanhumanMICNAGram-negative anaerobesNAClindamycinGram-negative anaerobesNA44FALSEFALSEFALSENAAnaerobes, Gramnegative
994NANAhumanhumanMICNAGram-negative anaerobesNADoxycyclineGram-negative anaerobesNANoteNoteFALSEFALSEFALSENAAnaerobes, Gramnegative
995NANAhumanhumanMICNAGram-negative anaerobesNAEravacyclineGram-negative anaerobesNAIEIEFALSEFALSEFALSENAAnaerobes, Gramnegative
996NANAhumanhumanMICNAGram-negative anaerobesNAMinocyclineGram-negative anaerobesNANoteNoteFALSEFALSEFALSENAAnaerobes, Gramnegative
997NANAhumanhumanMICNAGram-negative anaerobesNATetracyclineGram-negative anaerobesNANoteNoteFALSEFALSEFALSENAAnaerobes, Gramnegative
998NANAhumanhumanMICNAGram-negative anaerobesNATigecyclineGram-negative anaerobesNANoteNoteFALSEFALSEFALSENAAnaerobes, Gramnegative
999NANAhumanhumanMICNAGram-negative anaerobesNAChloramphenicolGram-negative anaerobesNA88FALSEFALSEFALSENAAnaerobes, Gramnegative
1000NANAhumanhumanMICNAGram-negative anaerobesNAMetronidazoleGram-negative anaerobesNA44FALSEFALSEFALSENAAnaerobes, Gramnegative
1001NANAhumanhumanMICNAHelicobacter pyloriNAAmoxicillinHelicobacter pyloriNA0.1250.125FALSEFALSEFALSENAH.pylori
1002NANAhumanhumanMICNAHelicobacter pyloriNALevofloxacinHelicobacter pyloriNA11FALSEFALSEFALSENAH.pylori
1003NANAhumanhumanMICNAHelicobacter pyloriNAClarithromycinHelicobacter pyloriNA0.250.5FALSEFALSEFALSENAH.pylori
1004NANAhumanhumanMICNAHelicobacter pyloriNATetracyclineHelicobacter pyloriNA11FALSEFALSEFALSENAH.pylori
1005NANAhumanhumanMICNAHelicobacter pyloriNAMetronidazoleHelicobacter pyloriNA88FALSEFALSEFALSENAH.pylori
1006NANAhumanhumanMICNAHelicobacter pyloriNARifampicinHelicobacter pyloriNA11FALSEFALSEFALSENAH.pylori
1007EUCAST 20199.0humanhumanMICNAListeria monocytogenesNABenzylpenicillinListeria monocytogenesNA11FALSEFALSEFALSENAL.monocytogenes
1008EUCAST 20199.0humanhumanDISKNAListeria monocytogenesNABenzylpenicillinListeria monocytogenes1 unit1313FALSEFALSEFALSENAL.monocytogenes
1009EUCAST 20199.0humanhumanMICNAListeria monocytogenesNAAmpicillinListeria monocytogenesNA11FALSEFALSEFALSENAL.monocytogenes
1010EUCAST 20199.0humanhumanDISKNAListeria monocytogenesNAAmpicillinListeria monocytogenes2 mcg1616FALSEFALSEFALSENAL.monocytogenes
1011EUCAST 20199.0humanhumanMICNAListeria monocytogenesNAMeropenemListeria monocytogenesNA0.250.25FALSEFALSEFALSENAL.monocytogenes
1012EUCAST 20199.0humanhumanDISKNAListeria monocytogenesNAMeropenemListeria monocytogenes10 mcg2626FALSEFALSEFALSENAL.monocytogenes
1013EUCAST 20199.0humanhumanMICNAListeria monocytogenesNAErythromycinListeria monocytogenesNA11FALSEFALSEFALSENAL.monocytogenes
1014EUCAST 20199.0humanhumanDISKNAListeria monocytogenesNAErythromycinListeria monocytogenes15 mcg2525FALSEFALSEFALSENAL.monocytogenes
1015EUCAST 20199.0humanhumanMICNAListeria monocytogenesNATrimethoprim-sulfamethoxazoleListeria monocytogenesNA0.060.06FALSEFALSEFALSENAL.monocytogenes
1016EUCAST 20199.0humanhumanDISKNAListeria monocytogenesNATrimethoprim-sulfamethoxazoleListeria monocytogenes1.25/23.75 mcg2929FALSEFALSEFALSENAL.monocytogenes
1017EUCAST 20199.0humanhumanMICNAPasteurella multocidaNABenzylpenicillinPasteurella multocidaNA0.50.5FALSEFALSEFALSENAP.multocida
1018EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNABenzylpenicillinPasteurella multocida1 unit1717FALSEFALSEFALSENAP.multocida
1019EUCAST 20199.0humanhumanMICNAPasteurella multocidaNAAmpicillinPasteurella multocidaNA11FALSEFALSEFALSE[A] Infer susceptibility from benzylpenicillin susceptibility.P.multocida
1020EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNAAmpicillinPasteurella multocidaNANoteNoteFALSEFALSEFALSE[A] Infer susceptibility from benzylpenicillin susceptibility.P.multocida
1021EUCAST 20199.0humanhumanMICNAPasteurella multocidaNAAmoxicillinPasteurella multocidaNA11FALSEFALSEFALSE[A] Infer susceptibility from benzylpenicillin susceptibility.P.multocida
1022EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNAAmoxicillinPasteurella multocidaNANoteNoteFALSEFALSEFALSE[A] Infer susceptibility from benzylpenicillin susceptibility.P.multocida
1023EUCAST 20199.0humanhumanMICNAPasteurella multocidaNAAmoxicillin-clavulanic acidPasteurella multocidaNA11FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.P.multocida
1024EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNAAmoxicillin-clavulanic acidPasteurella multocida2/1 mcg1515FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.P.multocida
1025EUCAST 20199.0humanhumanMICNAPasteurella multocidaNACefotaximePasteurella multocidaNA0.030.03FALSEFALSEFALSENAP.multocida
1026EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNACefotaximePasteurella multocida5 mcg2626FALSEFALSEFALSENAP.multocida
1027EUCAST 20199.0humanhumanMICNAPasteurella multocidaNACiprofloxacinPasteurella multocidaNA0.060.06FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See Note B.P.multocida
1028EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNACiprofloxacinPasteurella multocida5 mcg2727FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See Note B.P.multocida
1029EUCAST 20199.0humanhumanMICNAPasteurella multocidaNALevofloxacinPasteurella multocidaNA0.060.06FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See Note B.P.multocida
1030EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNALevofloxacinPasteurella multocida5 mcg2727FALSEFALSEFALSE[A] The nalidixic acid disk diffusion test can be used to screen for fluoroquinolone resistance. See Note B.P.multocida
1031EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNANalidixic acid (screen)Pasteurella multocida30 mcg23NoteFALSEFALSEFALSE[B] Isolates categorised as susceptible to nalidixic acid can be reported susceptible to ciprofloxacin and levofloxacin. Isolates categorised as non-susceptible may have fluoroquinolone resistance and should be tested against the appropriate agent.P.multocida
1032EUCAST 20199.0humanhumanMICNAPasteurella multocidaNADoxycyclinePasteurella multocidaNA11FALSEFALSEFALSE[A] Susceptibility inferred from tetracycline screen test.P.multocida
1033EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNADoxycyclinePasteurella multocidaNANoteNoteFALSEFALSEFALSE[A] Susceptibility inferred from tetracycline screen test.P.multocida
1034EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNATetracycline (screen)Pasteurella multocida30 mcg2424FALSEFALSEFALSE[A] Susceptibility inferred from tetracycline screen test.P.multocida
1035EUCAST 20199.0humanhumanMICNAPasteurella multocidaNATrimethoprim-sulfamethoxazolePasteurella multocidaNA0.250.25FALSEFALSEFALSENAP.multocida
1036EUCAST 20199.0humanhumanDISKNAPasteurella multocidaNATrimethoprim-sulfamethoxazolePasteurella multocida1.25/23.75 mcg2323FALSEFALSEFALSENAP.multocida
1037EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNACiprofloxacinCampylobacter jejuni and coliNA0.50.5FALSEFALSEFALSENAC.jejuni_C.coli
1038EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNACiprofloxacinCampylobacter jejuni and coli5 mcg2626FALSEFALSEFALSENAC.jejuni_C.coli
1039EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNAAzithromycinCampylobacter jejuni and coliNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1040EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNAAzithromycinCampylobacter jejuni and coliNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1041EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNAClarithromycinCampylobacter jejuni and coliNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1042EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNAClarithromycinCampylobacter jejuni and coliNANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1043EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNAErythromycin,C. jejuniCampylobacter jejuni and coliNA44FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1044EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNAErythromycin,C. jejuniCampylobacter jejuni and coli15 mcg2020FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1045EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNAErythromycin,C. coliCampylobacter jejuni and coliNA88FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1046EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNAErythromycin,C. coliCampylobacter jejuni and coli15 mcg2424FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin and clarithromycin.C.jejuni_C.coli
1047EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNADoxycyclineCampylobacter jejuni and coliNANoteNoteFALSEFALSEFALSE[1/A] Tetracycline can be used to determine susceptibility to doxycycline.C.jejuni_C.coli
1048EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNADoxycyclineCampylobacter jejuni and coliNANoteNoteFALSEFALSEFALSE[1/A] Tetracycline can be used to determine susceptibility to doxycycline.C.jejuni_C.coli
1049EUCAST 20199.0humanhumanMICNACampylobacter jejuni and coliNATetracyclineCampylobacter jejuni and coliNA22FALSEFALSEFALSE[1/A] Tetracycline can be used to determine susceptibility to doxycycline.C.jejuni_C.coli
1050EUCAST 20199.0humanhumanDISKNACampylobacter jejuni and coliNATetracyclineCampylobacter jejuni and coli30 mcg3030FALSEFALSEFALSE[1/A] Tetracycline can be used to determine susceptibility to doxycycline.C.jejuni_C.coli
1051EUCAST 20199.0humanhumanMICNACorynebacterium spp.NABenzylpenicillinCorynebacterium spp.NA0.1250.125FALSEFALSEFALSENACorynebacterium
1052EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NABenzylpenicillinCorynebacterium spp.1 unit2929FALSEFALSEFALSENACorynebacterium
1053EUCAST 20199.0humanhumanMICNACorynebacterium spp.NACiprofloxacinCorynebacterium spp.NA11FALSEFALSEFALSENACorynebacterium
1054EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NACiprofloxacinCorynebacterium spp.5 mcg2525FALSEFALSEFALSENACorynebacterium
1055EUCAST 20199.0humanhumanMICNACorynebacterium spp.NAMoxifloxacinCorynebacterium spp.NA0.50.5FALSEFALSEFALSENACorynebacterium
1056EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NAMoxifloxacinCorynebacterium spp.5 mcg2525FALSEFALSEFALSENACorynebacterium
1057EUCAST 20199.0humanhumanMICNACorynebacterium spp.NAGentamicinCorynebacterium spp.NA11FALSEFALSEFALSENACorynebacterium
1058EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NAGentamicinCorynebacterium spp.10 mcg2323FALSEFALSEFALSENACorynebacterium
1059EUCAST 20199.0humanhumanMICNACorynebacterium spp.NAVancomycinCorynebacterium spp.NA22FALSEFALSEFALSE[A] Non-wild typeisolates were not available when developing the disk diffusion method.Corynebacterium
1060EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NAVancomycinCorynebacterium spp.5 mcg1717FALSEFALSEFALSE[A] Non-wild typeisolates were not available when developing the disk diffusion method.Corynebacterium
1061EUCAST 20199.0humanhumanMICNACorynebacterium spp.NAErythromycinCorynebacterium spp.NAIPIPFALSEFALSEFALSENACorynebacterium
1062EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NAErythromycinCorynebacterium spp.15 mcgIPIPFALSEFALSEFALSENACorynebacterium
1063EUCAST 20199.0humanhumanMICNACorynebacterium spp.NAClindamycinCorynebacterium spp.NA0.50.5FALSEFALSEFALSENACorynebacterium
1064EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NAClindamycinCorynebacterium spp.2 mcg2020FALSEFALSEFALSENACorynebacterium
1065EUCAST 20199.0humanhumanMICNACorynebacterium spp.NATetracyclineCorynebacterium spp.NA22FALSEFALSEFALSENACorynebacterium
1066EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NATetracyclineCorynebacterium spp.30 mcg2424FALSEFALSEFALSENACorynebacterium
1067EUCAST 20199.0humanhumanMICNACorynebacterium spp.NALinezolidCorynebacterium spp.NA22FALSEFALSEFALSENACorynebacterium
1068EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NALinezolidCorynebacterium spp.10 mcg2525FALSEFALSEFALSENACorynebacterium
1069EUCAST 20199.0humanhumanMICNACorynebacterium spp.NARifampicinCorynebacterium spp.NA0.060.5FALSEFALSEFALSENACorynebacterium
1070EUCAST 20199.0humanhumanDISKNACorynebacterium spp.NARifampicinCorynebacterium spp.5 mcg3025FALSEFALSEFALSENACorynebacterium
1071EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNABenzylpenicillinAerococcus sanguinicola and urinaeNA0.1250.125FALSEFALSEFALSENAA.sanguinicola_A.urinae
1072EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNABenzylpenicillinAerococcus sanguinicola and urinae1 unit2121FALSEFALSEFALSENAA.sanguinicola_A.urinae
1073EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNAAmpicillinAerococcus sanguinicola and urinaeNA0.250.25FALSEFALSEFALSENAA.sanguinicola_A.urinae
1074EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNAAmpicillinAerococcus sanguinicola and urinae2 mcg2626FALSEFALSEFALSENAA.sanguinicola_A.urinae
1075EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNAAmoxicillinAerococcus sanguinicola and urinaeNANoteNoteFALSEFALSEFALSE[1/A] Infer susceptibility from ampicillin susceptibility.A.sanguinicola_A.urinae
1076EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNAAmoxicillinAerococcus sanguinicola and urinaeNANoteNoteFALSEFALSEFALSE[1/A] Infer susceptibility from ampicillin susceptibility.A.sanguinicola_A.urinae
1077EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNAMeropenemAerococcus sanguinicola and urinaeNA0.250.25FALSEFALSEFALSENAA.sanguinicola_A.urinae
1078EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNAMeropenemAerococcus sanguinicola and urinae10 mcg3131FALSEFALSEFALSENAA.sanguinicola_A.urinae
1079EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNACiprofloxacin (uncomplicated UTI only)Aerococcus sanguinicola and urinaeNA22FALSEFALSEFALSE[A] Susceptibility can be inferred from norfloxacin susceptibility. See NoteA.sanguinicola_A.urinae
1080EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNACiprofloxacin (uncomplicated UTI only)Aerococcus sanguinicola and urinae5 mcg2121FALSEFALSEFALSE[A] Susceptibility can be inferred from norfloxacin susceptibility. See NoteA.sanguinicola_A.urinae
1081EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNALevofloxacin (uncomplicated UTI only)Aerococcus sanguinicola and urinaeNA22FALSEFALSEFALSE[1] Susceptibility can be inferred from ciprofloxacin susceptibility. | [B] Susceptibility can be inferred from ciprofloxacin or norfloxacin susceptibility. See NoteA.sanguinicola_A.urinae
1082EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNALevofloxacin (uncomplicated UTI only)Aerococcus sanguinicola and urinae5 mcgNoteNoteFALSEFALSEFALSE[1] Susceptibility can be inferred from ciprofloxacin susceptibility. | [B] Susceptibility can be inferred from ciprofloxacin or norfloxacin susceptibility. See NoteA.sanguinicola_A.urinae
1083EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNANorfloxacin (screen)Aerococcus sanguinicola and urinae10 mcg1717FALSEFALSEFALSE[C] | [C] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance.A.sanguinicola_A.urinae
1084EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNAVancomycinAerococcus sanguinicola and urinaeNA11FALSEFALSEFALSE[A] Non-wild type isolates were not available when developing the disk diffusion method.A.sanguinicola_A.urinae
1085EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNAVancomycinAerococcus sanguinicola and urinae5 mcg1616FALSEFALSEFALSE[A] Non-wild type isolates were not available when developing the disk diffusion method.A.sanguinicola_A.urinae
1086EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNANitrofurantoin (uncomplicated UTI only)Aerococcus sanguinicola and urinaeNA1616FALSEFALSEFALSENAA.sanguinicola_A.urinae
1087EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNANitrofurantoin (uncomplicated UTI only)Aerococcus sanguinicola and urinae100 mcg1616FALSEFALSEFALSENAA.sanguinicola_A.urinae
1088EUCAST 20199.0humanhumanMICNAAerococcus sanguinicola and urinaeNARifampicinAerococcus sanguinicola and urinaeNA0.1250.125FALSEFALSEFALSENAA.sanguinicola_A.urinae
1089EUCAST 20199.0humanhumanDISKNAAerococcus sanguinicola and urinaeNARifampicinAerococcus sanguinicola and urinae5 mcg2525FALSEFALSEFALSENAA.sanguinicola_A.urinae
1090EUCAST 20199.0humanhumanMICNAKingella kingaeNABenzylpenicillinKingella kingaeNA0.030.03FALSEFALSEFALSENAK.kingae
1091EUCAST 20199.0humanhumanDISKNAKingella kingaeNABenzylpenicillinKingella kingae1 unit2525FALSEFALSEFALSENAK.kingae
1092EUCAST 20199.0humanhumanMICNAKingella kingaeNAAmpicillinKingella kingaeNA0.060.06FALSEFALSEFALSE[2] Susceptibility can be inferred from benzylpenicillin susceptibility. | [A] Infer susceptibility from benzylpenicillin susceptibility.K.kingae
1093EUCAST 20199.0humanhumanDISKNAKingella kingaeNAAmpicillinKingella kingaeNANoteNoteFALSEFALSEFALSE[2] Susceptibility can be inferred from benzylpenicillin susceptibility. | [A] Infer susceptibility from benzylpenicillin susceptibility.K.kingae
1094EUCAST 20199.0humanhumanMICNAKingella kingaeNAAmoxicillinKingella kingaeNA0.1250.125FALSEFALSEFALSE[2] Susceptibility can be inferred from benzylpenicillin susceptibility. | [A] Infer susceptibility from benzylpenicillin susceptibility.K.kingae
1095EUCAST 20199.0humanhumanDISKNAKingella kingaeNAAmoxicillinKingella kingaeNANoteNoteFALSEFALSEFALSE[2] Susceptibility can be inferred from benzylpenicillin susceptibility. | [A] Infer susceptibility from benzylpenicillin susceptibility.K.kingae
1096EUCAST 20199.0humanhumanMICNAKingella kingaeNAAmoxicillin-clavulanic acidKingella kingaeNANoteNoteFALSEFALSEFALSE[3/B] The intrinsic activity of clavulanic acid in K. kingae is such that the organism is inhibited by 2 mg/L clavulanic acid.Therefore no breakpoints for amoxicillin-clavulanic acid can be given.K.kingae
1097EUCAST 20199.0humanhumanDISKNAKingella kingaeNAAmoxicillin-clavulanic acidKingella kingaeNANoteNoteFALSEFALSEFALSE[3/B] The intrinsic activity of clavulanic acid in K. kingae is such that the organism is inhibited by 2 mg/L clavulanic acid.Therefore no breakpoints for amoxicillin-clavulanic acid can be given.K.kingae
1098EUCAST 20199.0humanhumanMICNAKingella kingaeNACefotaximeKingella kingaeNA0.1250.125FALSEFALSEFALSENAK.kingae
1099EUCAST 20199.0humanhumanDISKNAKingella kingaeNACefotaximeKingella kingae5 mcg2727FALSEFALSEFALSENAK.kingae
1100EUCAST 20199.0humanhumanMICNAKingella kingaeNACeftriaxoneKingella kingaeNA0.060.06FALSEFALSEFALSENAK.kingae
1101EUCAST 20199.0humanhumanDISKNAKingella kingaeNACeftriaxoneKingella kingae30 mcg3030FALSEFALSEFALSENAK.kingae
1102EUCAST 20199.0humanhumanMICNAKingella kingaeNACefuroxime ivKingella kingaeNA0.50.5FALSEFALSEFALSENAK.kingae
1103EUCAST 20199.0humanhumanDISKNAKingella kingaeNACefuroxime ivKingella kingae30 mcg2929FALSEFALSEFALSENAK.kingae
1104EUCAST 20199.0humanhumanMICNAKingella kingaeNAMeropenemKingella kingaeNA0.030.03FALSEFALSEFALSENAK.kingae
1105EUCAST 20199.0humanhumanDISKNAKingella kingaeNAMeropenemKingella kingae10 mcg3030FALSEFALSEFALSENAK.kingae
1106EUCAST 20199.0humanhumanMICNAKingella kingaeNACiprofloxacinKingella kingaeNA0.060.06FALSEFALSEFALSENAK.kingae
1107EUCAST 20199.0humanhumanDISKNAKingella kingaeNACiprofloxacinKingella kingae5 mcg2828FALSEFALSEFALSENAK.kingae
1108EUCAST 20199.0humanhumanMICNAKingella kingaeNALevofloxacinKingella kingaeNA0.1250.125FALSEFALSEFALSENAK.kingae
1109EUCAST 20199.0humanhumanDISKNAKingella kingaeNALevofloxacinKingella kingae5 mcg2828FALSEFALSEFALSENAK.kingae
1110EUCAST 20199.0humanhumanMICNAKingella kingaeNAAzithromycinKingella kingaeNA0.250.25FALSEFALSEFALSE[1] Susceptibility can be inferred from erythromycin susceptibility. | [A] Infer susceptibility from erythromycin susceptibility.K.kingae
1111EUCAST 20199.0humanhumanDISKNAKingella kingaeNAAzithromycinKingella kingaeNANoteNoteFALSEFALSEFALSE[1] Susceptibility can be inferred from erythromycin susceptibility. | [A] Infer susceptibility from erythromycin susceptibility.K.kingae
1112EUCAST 20199.0humanhumanMICNAKingella kingaeNAClarithromycinKingella kingaeNA0.50.5FALSEFALSEFALSE[1] Susceptibility can be inferred from erythromycin susceptibility. | [A] Infer susceptibility from erythromycin susceptibility.K.kingae
1113EUCAST 20199.0humanhumanDISKNAKingella kingaeNAClarithromycinKingella kingaeNANoteNoteFALSEFALSEFALSE[1] Susceptibility can be inferred from erythromycin susceptibility. | [A] Infer susceptibility from erythromycin susceptibility.K.kingae
1114EUCAST 20199.0humanhumanMICNAKingella kingaeNAErythromycinKingella kingaeNA0.50.5FALSEFALSEFALSENAK.kingae
1115EUCAST 20199.0humanhumanDISKNAKingella kingaeNAErythromycinKingella kingae15 mcg2020FALSEFALSEFALSENAK.kingae
1116EUCAST 20199.0humanhumanMICNAKingella kingaeNADoxycyclineKingella kingaeNA0.50.5FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline, but some resistant to tetracycline may be susceptible to doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.K.kingae
1117EUCAST 20199.0humanhumanDISKNAKingella kingaeNADoxycyclineKingella kingaeNANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline, but some resistant to tetracycline may be susceptible to doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.K.kingae
1118EUCAST 20199.0humanhumanMICNAKingella kingaeNATetracyclineKingella kingaeNA0.50.5FALSEFALSEFALSENAK.kingae
1119EUCAST 20199.0humanhumanDISKNAKingella kingaeNATetracyclineKingella kingae30 mcg2828FALSEFALSEFALSENAK.kingae
1120EUCAST 20199.0humanhumanMICNAKingella kingaeNARifampicinKingella kingaeNA0.50.5FALSEFALSEFALSENAK.kingae
1121EUCAST 20199.0humanhumanDISKNAKingella kingaeNARifampicinKingella kingae5 mcg2020FALSEFALSEFALSENAK.kingae
1122EUCAST 20199.0humanhumanMICNAKingella kingaeNATrimethoprim-sulfamethoxazoleKingella kingaeNA0.250.25FALSEFALSEFALSENAK.kingae
1123EUCAST 20199.0humanhumanDISKNAKingella kingaeNATrimethoprim-sulfamethoxazoleKingella kingae1.25/23.75 mcg2828FALSEFALSEFALSENAK.kingae
1124EUCAST 20199.0humanhumanMICNAAeromonas spp.NACefepimeAeromonas spp.NA14FALSEFALSEFALSENAAeromonas
1125EUCAST 20199.0humanhumanDISKNAAeromonas spp.NACefepimeAeromonas spp.30 mcg2724FALSEFALSEFALSENAAeromonas
1126EUCAST 20199.0humanhumanMICNAAeromonas spp.NACeftazidimeAeromonas spp.NA14FALSEFALSEFALSENAAeromonas
1127EUCAST 20199.0humanhumanDISKNAAeromonas spp.NACeftazidimeAeromonas spp.10 mcg2421FALSEFALSEFALSENAAeromonas
1128EUCAST 20199.0humanhumanMICNAAeromonas spp.NAAztreonamAeromonas spp.NA14FALSEFALSEFALSENAAeromonas
1129EUCAST 20199.0humanhumanDISKNAAeromonas spp.NAAztreonamAeromonas spp.30 mcg2926FALSEFALSEFALSENAAeromonas
1130EUCAST 20199.0humanhumanMICNAAeromonas spp.NACiprofloxacinAeromonas spp.NA0.250.5FALSEFALSEFALSENAAeromonas
1131EUCAST 20199.0humanhumanDISKNAAeromonas spp.NACiprofloxacinAeromonas spp.5 mcg2724FALSEFALSEFALSENAAeromonas
1132EUCAST 20199.0humanhumanMICNAAeromonas spp.NALevofloxacinAeromonas spp.NA0.51FALSEFALSEFALSENAAeromonas
1133EUCAST 20199.0humanhumanDISKNAAeromonas spp.NALevofloxacinAeromonas spp.5 mcg2724FALSEFALSEFALSENAAeromonas
1134EUCAST 20199.0humanhumanMICNAAeromonas spp.NATrimethoprim-sulfamethoxazoleAeromonas spp.NA24FALSEFALSEFALSE[A] Read the obvious zone edge and disregard haze or growth within the inhibition zone (see pictures below).Aeromonas
1135EUCAST 20199.0humanhumanDISKNAAeromonas spp.NATrimethoprim-sulfamethoxazoleAeromonas spp.1.25/23.75 mcg1916FALSEFALSEFALSE[A] Read the obvious zone edge and disregard haze or growth within the inhibition zone (see pictures below).Aeromonas
1136EUCAST 20199.0humanhumanMICNAThe Mycobacterium tuberculosis complex includes different species and variants such as M. tuberculosis var. canetti, M. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.NADelamanidThe Mycobacterium tuberculosis complex includes different species and variants such as M. tuberculosis var. canetti, M. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.NA0.060.06FALSEFALSEFALSENAM.tuberculosis
1137EUCAST 20199.0humanhumanMICNAThe Mycobacterium tuberculosis complex includes different species and variants such as M. tuberculosis var. canetti, M. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.NABedaquilineThe Mycobacterium tuberculosis complex includes different species and variants such as M. tuberculosis var. canetti, M. tuberculosis var. tuberculosis, M. tuberculosis var. africanum and M. tuberculosis var. bovis. Breakpoints have only been established for M. tuberculosis var. tuberculosis.NA0.250.25FALSEFALSEFALSENAM.tuberculosis
1138EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmpicillinEnterobacteralesNA88FALSEFALSEFALSE[A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1139EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmpicillinEnterobacterales10 mcg1414FALSEFALSEFALSE[A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1140EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmpicillin-sulbactamEnterobacteralesNA88FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1141EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmpicillin-sulbactamEnterobacterales10/10 mcg1414FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of sulbactam is fixed at 4 mg/L. | [A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1142EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmoxicillinEnterobacteralesNA88FALSEFALSEFALSE[B] Susceptibility inferred from ampicillin.Enterobacterales
1143EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmoxicillinEnterobacterales/ mcgNoteNoteFALSEFALSEFALSE[B] Susceptibility inferred from ampicillin.Enterobacterales
1144EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmoxicillin-clavulanic acidEnterobacteralesNA88FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1145EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmoxicillin-clavulanic acidEnterobacterales20/10 mcg1919FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1146EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmoxicillin-clavulanic acid (uncomplicated UTI only)EnterobacteralesNA3232FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1147EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmoxicillin-clavulanic acid (uncomplicated UTI only)Enterobacterales20/10 mcg1616FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L. | [A] Wild type Enterobacterales are categorised as susceptible to aminopenicillins. Some countries prefer to categorise wild-type isolates of E. coli and P. mirabilis as "Susceptible, increased exposure". When this is the case, use the MIC breakpoint S ≤ 0.5 mg/L and the corresponding zone diameter breakpoint S ≥ 50 mm. | [A] Ignore growth that may appear as a thin inner zone on some batches of Mueller-Hinton agars.Enterobacterales
1148EUCAST 202010.0humanhumanMICNAEnterobacteralesNAPiperacillinEnterobacteralesNA816FALSEFALSEFALSENAEnterobacterales
1149EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAPiperacillinEnterobacterales30 mcg2017FALSEFALSEFALSENAEnterobacterales
1150EUCAST 202010.0humanhumanMICNAEnterobacteralesNAPiperacillin-tazobactamEnterobacteralesNA816FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
1151EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAPiperacillin-tazobactamEnterobacterales30/6 mcg2017FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
1152EUCAST 202010.0humanhumanMICNAEnterobacteralesNATicarcillinEnterobacteralesNA816FALSEFALSEFALSENAEnterobacterales
1153EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATicarcillinEnterobacterales75 mcg2320FALSEFALSEFALSENAEnterobacterales
1154EUCAST 202010.0humanhumanMICNAEnterobacteralesNATicarcillin-clavulanic acidEnterobacteralesNA816FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Enterobacterales
1155EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATicarcillin-clavulanic acidEnterobacterales75/10 mcg2320FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Enterobacterales
1156EUCAST 202010.0humanhumanMICNAEnterobacteralesNATemocillinEnterobacteralesNANoteNoteFALSEFALSEFALSE[5/C] Breakpoints still under consideration.Enterobacterales
1157EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATemocillinEnterobacteralesNANoteNoteFALSEFALSEFALSE[5/C] Breakpoints still under consideration.Enterobacterales
1158EUCAST 202010.0humanhumanMICNAEnterobacteralesNAMecillinam oral (uncomplicated UTI only), E. coli, Citrobacter spp., Klebsiella spp., Raoultella spp., Enterobacter spp. and P. mirabilisEnterobacteralesNA88FALSEFALSEFALSE[6] Agar dilution is the reference method for mecillinam MIC determination. | [D] Ignore isolated colonies within the inhibition zone. for E. coliEnterobacterales
1159EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAMecillinam oral (uncomplicated UTI only), E. coli, Citrobacter spp., Klebsiella spp., Raoultella spp., Enterobacter spp. and P. mirabilisEnterobacterales10 mcg1515FALSEFALSEFALSE[6] Agar dilution is the reference method for mecillinam MIC determination. | [D] Ignore isolated colonies within the inhibition zone. for E. coliEnterobacterales
1160EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefadroxil (uncomplicated UTI only)EnterobacteralesNA1616FALSEFALSEFALSENAEnterobacterales
1161EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefadroxil (uncomplicated UTI only)Enterobacterales30 mcg1212FALSEFALSEFALSENAEnterobacterales
1162EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefalexin (uncomplicated UTI only)EnterobacteralesNA1616FALSEFALSEFALSENAEnterobacterales
1163EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefalexin (uncomplicated UTI only)Enterobacterales30 mcg1414FALSEFALSEFALSENAEnterobacterales
1164EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefazolin (infections originating from the urinary tract), E. coli, and Klebsiella spp. (except K. aerogenes)EnterobacteralesNA0.0014FALSEFALSEFALSENAEnterobacterales
1165EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefazolin (infections originating from the urinary tract), E. coli, and Klebsiella spp. (except K. aerogenes)EnterobacteralesIP mcgIPIPFALSEFALSEFALSENAEnterobacterales
1166EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefepimeEnterobacteralesNA14FALSEFALSEFALSENAEnterobacterales
1167EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefepimeEnterobacterales30 mcg2724FALSEFALSEFALSENAEnterobacterales
1168EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefixime (uncomplicated UTI only)EnterobacteralesNA11FALSEFALSEFALSENAEnterobacterales
1169EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefixime (uncomplicated UTI only)Enterobacterales5 mcg1717FALSEFALSEFALSENAEnterobacterales
1170EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefotaximeEnterobacteralesNA12FALSEFALSEFALSENAEnterobacterales
1171EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefotaximeEnterobacterales5 mcg2017FALSEFALSEFALSENAEnterobacterales
1172EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefoxitin (screen only)Enterobacterales30 mcg1919FALSEFALSEFALSENAEnterobacterales
1173EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefpodoxime (uncomplicated UTI only)EnterobacteralesNA11FALSEFALSEFALSENAEnterobacterales
1174EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefpodoxime (uncomplicated UTI only)Enterobacterales10 mcg2121FALSEFALSEFALSENAEnterobacterales
1175EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftarolineEnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
1176EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftarolineEnterobacterales5 mcg2323FALSEFALSEFALSENAEnterobacterales
1177EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftazidimeEnterobacteralesNA14FALSEFALSEFALSENAEnterobacterales
1178EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftazidimeEnterobacterales10 mcg2219FALSEFALSEFALSENAEnterobacterales
1179EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftazidime-avibactamEnterobacteralesNA88FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Enterobacterales
1180EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftazidime-avibactamEnterobacterales10/4 mcg1313FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Enterobacterales
1181EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftibuten (infections originating from the urinary tract)EnterobacteralesNA11FALSEFALSEFALSENAEnterobacterales
1182EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftibuten (infections originating from the urinary tract)Enterobacterales30 mcg2323FALSEFALSEFALSENAEnterobacterales
1183EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftobiproleEnterobacteralesNA0.250.25FALSEFALSEFALSENAEnterobacterales
1184EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftobiproleEnterobacterales5 mcg2323FALSEFALSEFALSENAEnterobacterales
1185EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftolozane-tazobactamEnterobacteralesNA22FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
1186EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftolozane-tazobactamEnterobacterales30/10 mcg2222FALSEFALSEFALSE[5] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Enterobacterales
1187EUCAST 202010.0humanhumanMICNAEnterobacteralesNACeftriaxoneEnterobacteralesNA12FALSEFALSEFALSENAEnterobacterales
1188EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACeftriaxoneEnterobacterales30 mcg2522FALSEFALSEFALSENAEnterobacterales
1189EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefuroxime iv, E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacteralesNA0.0018FALSEFALSEFALSENAEnterobacterales
1190EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefuroxime iv, E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacterales30 mcg5019FALSEFALSEFALSENAEnterobacterales
1191EUCAST 202010.0humanhumanMICNAEnterobacteralesNACefuroxime oral (uncomplicated UTI only), E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacteralesNA88FALSEFALSEFALSENAEnterobacterales
1192EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACefuroxime oral (uncomplicated UTI only), E. coli, Klebsiella spp. (except K. aerogenes), Raoultella spp. and P. mirabilisEnterobacterales30 mcg1919FALSEFALSEFALSENAEnterobacterales
1193EUCAST 202010.0humanhumanMICNAEnterobacteralesNAErtapenemEnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
1194EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAErtapenemEnterobacterales10 mcg2525FALSEFALSEFALSENAEnterobacterales
1195EUCAST 202010.0humanhumanMICNAEnterobacteralesNAImipenemEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
1196EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAImipenemEnterobacterales10 mcg2217FALSEFALSEFALSENAEnterobacterales
1197EUCAST 202010.0humanhumanMICNAEnterobacteralesNAImipenem, Morganella morganii,Proteus spp. and Providencia spp.EnterobacteralesNA0.0014FALSEFALSEFALSENAEnterobacterales
1198EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAImipenem, Morganella morganii,Proteus spp. and Providencia spp.Enterobacterales10 mcg5017FALSEFALSEFALSENAEnterobacterales
1199EUCAST 202010.0humanhumanMICNAEnterobacteralesNAImipenem-relebactam, Enterobacterales except Morganella spp.EnterobacteralesNA22FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of relebactam is fixed at 4 mg/L.Enterobacterales
1200EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAImipenem-relebactam, Enterobacterales except Morganella spp.EnterobacteralesIP mcgIPIPFALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of relebactam is fixed at 4 mg/L.Enterobacterales
1201EUCAST 202010.0humanhumanMICNAEnterobacteralesNAMeropenemEnterobacteralesNA28FALSEFALSEFALSENAEnterobacterales
1202EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAMeropenemEnterobacterales10 mcg2216FALSEFALSEFALSENAEnterobacterales
1203EUCAST 202010.0humanhumanMICNAEnterobacteralesNAMeropenem-vaborbactamEnterobacteralesNA88FALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Enterobacterales
1204EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAMeropenem-vaborbactamEnterobacteralesIP mcgIPIPFALSEFALSEFALSE[4] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Enterobacterales
1205EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAztreonamEnterobacteralesNA14FALSEFALSEFALSENAEnterobacterales
1206EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAztreonamEnterobacterales30 mcg2621FALSEFALSEFALSENAEnterobacterales
1207EUCAST 202010.0humanhumanMICNAEnterobacteralesNACiprofloxacinEnterobacteralesNA0.250.5FALSEFALSEFALSENAEnterobacterales
1208EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACiprofloxacinEnterobacterales5 mcg2522FALSEFALSEFALSENAEnterobacterales
1209EUCAST 202010.0humanhumanMICNAEnterobacteralesNACiprofloxacin, Salmonella spp.EnterobacteralesNA0.060.06FALSEFALSEFALSE[A] Tests with a ciprofloxacin 5 µg disk will not reliably detect low-level resistance in Salmonella spp. To screen for ciprofloxacin resistance in Salmonella spp., use the pefloxacin 5 µg disk. See NoteEnterobacterales
1210EUCAST 202010.0humanhumanDISKNAEnterobacteralesNACiprofloxacin, Salmonella spp.EnterobacteralesNANoteNoteFALSEFALSEFALSE[A] Tests with a ciprofloxacin 5 µg disk will not reliably detect low-level resistance in Salmonella spp. To screen for ciprofloxacin resistance in Salmonella spp., use the pefloxacin 5 µg disk. See NoteEnterobacterales
1211EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAPefloxacin (screen only)Salmonella spp.Enterobacterales5 mcg2424FALSEFALSEFALSE[B] | [B] Susceptibility of Salmonella spp. to ciprofloxacin can be inferred from pefloxacin disk diffusion susceptibility. | [C] The pefloxacin 5 µg breakpoint used to screen for clinical fluoroquinolone resistance in Salmonella spp., can also be used to detect fluoroquinolone resistance mechanisms in other Enterobacterales such as E. coli, K. pneumoniae and Shigella spp.Enterobacterales
1212EUCAST 202010.0humanhumanMICNAEnterobacteralesNADelafloxacin, E. coliEnterobacteralesNA0.1250.125FALSEFALSEFALSE[D] A disk diffusion test is not yet developed. Perform an MIC test.Enterobacterales
1213EUCAST 202010.0humanhumanDISKNAEnterobacteralesNADelafloxacin, E. coliEnterobacteralesNANoteNoteFALSEFALSEFALSE[D] A disk diffusion test is not yet developed. Perform an MIC test.Enterobacterales
1214EUCAST 202010.0humanhumanMICNAEnterobacteralesNALevofloxacinEnterobacteralesNA0.51FALSEFALSEFALSENAEnterobacterales
1215EUCAST 202010.0humanhumanDISKNAEnterobacteralesNALevofloxacinEnterobacterales5 mcg2319FALSEFALSEFALSENAEnterobacterales
1216EUCAST 202010.0humanhumanMICNAEnterobacteralesNAMoxifloxacinEnterobacteralesNA0.250.25FALSEFALSEFALSENAEnterobacterales
1217EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAMoxifloxacinEnterobacterales5 mcg2222FALSEFALSEFALSENAEnterobacterales
1218EUCAST 202010.0humanhumanMICNAEnterobacteralesNANorfloxacin (uncomplicated UTI only)EnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
1219EUCAST 202010.0humanhumanDISKNAEnterobacteralesNANorfloxacin (uncomplicated UTI only)Enterobacterales10 mcg2222FALSEFALSEFALSENAEnterobacterales
1220EUCAST 202010.0humanhumanMICNAEnterobacteralesNAOfloxacinEnterobacteralesNA0.250.5FALSEFALSEFALSENAEnterobacterales
1221EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAOfloxacinEnterobacterales5 mcg2422FALSEFALSEFALSENAEnterobacterales
1222EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmikacin (systemic infections)EnterobacteralesNA88FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Enterobacterales
1223EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmikacin (systemic infections)Enterobacterales30 mcg1818FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Enterobacterales
1224EUCAST 202010.0humanhumanMICNAEnterobacteralesNAAmikacin (infections originating from the urinary tract)EnterobacteralesNA88FALSEFALSEFALSENAEnterobacterales
1225EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAAmikacin (infections originating from the urinary tract)Enterobacterales30 mcg1818FALSEFALSEFALSENAEnterobacterales
1226EUCAST 202010.0humanhumanMICNAEnterobacteralesNAGentamicin (systemic infections)EnterobacteralesNA22FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Enterobacterales
1227EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAGentamicin (systemic infections)Enterobacterales10 mcg1717FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Enterobacterales
1228EUCAST 202010.0humanhumanMICNAEnterobacteralesNAGentamicin (infections originating from the urinary tract)EnterobacteralesNA22FALSEFALSEFALSENAEnterobacterales
1229EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAGentamicin (infections originating from the urinary tract)Enterobacterales10 mcg1717FALSEFALSEFALSENAEnterobacterales
1230EUCAST 202010.0humanhumanMICNAEnterobacteralesNANetilmicinEnterobacteralesNAIEIEFALSEFALSEFALSENAEnterobacterales
1231EUCAST 202010.0humanhumanDISKNAEnterobacteralesNANetilmicinEnterobacteralesNAIEIEFALSEFALSEFALSENAEnterobacterales
1232EUCAST 202010.0humanhumanMICNAEnterobacteralesNATobramycin (systemic infections)EnterobacteralesNA22FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Enterobacterales
1233EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATobramycin (systemic infections)Enterobacterales10 mcg1717FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Enterobacterales
1234EUCAST 202010.0humanhumanMICNAEnterobacteralesNATobramycin (infections originating from the urinary tract)EnterobacteralesNA22FALSEFALSEFALSENAEnterobacterales
1235EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATobramycin (infections originating from the urinary tract)Enterobacterales10 mcg1717FALSEFALSEFALSENAEnterobacterales
1236EUCAST 202010.0humanhumanMICNAEnterobacteralesNAEravacycline, E. coliEnterobacteralesNA0.50.5FALSEFALSEFALSENAEnterobacterales
1237EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAEravacycline, E. coliEnterobacterales20 mcg1717FALSEFALSEFALSENAEnterobacterales
1238EUCAST 202010.0humanhumanMICNAEnterobacteralesNATigecycline,E. coli and C. koseriEnterobacteralesNA0.50.5FALSEFALSEFALSE[3/A] For other Enterobacterales, the activity of tigecycline varies from insufficient in Proteus spp., Morganella morganii and Providencia spp. to variable in other species. For more information, see http://www.eucast.org/guidance_documents/. | [2] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use. | [B] Zone diameter breakpoints validated for E. coli only. For C. koseri, use an MIC method.Enterobacterales
1239EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATigecycline,E. coli and C. koseriEnterobacterales15 mcg1818FALSEFALSEFALSE[3/A] For other Enterobacterales, the activity of tigecycline varies from insufficient in Proteus spp., Morganella morganii and Providencia spp. to variable in other species. For more information, see http://www.eucast.org/guidance_documents/. | [2] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use. | [B] Zone diameter breakpoints validated for E. coli only. For C. koseri, use an MIC method.Enterobacterales
1240EUCAST 202010.0humanhumanMICNAEnterobacteralesNAChloramphenicolEnterobacteralesNA88FALSEFALSEFALSENAEnterobacterales
1241EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAChloramphenicolEnterobacterales30 mcg1717FALSEFALSEFALSENAEnterobacterales
1242EUCAST 202010.0humanhumanMICNAEnterobacteralesNAColistinEnterobacteralesNA22FALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Enterobacterales
1243EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAColistinEnterobacteralesNANoteNoteFALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Enterobacterales
1244EUCAST 202010.0humanhumanMICNAEnterobacteralesNAFosfomycin ivEnterobacteralesNA3232FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
1245EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAFosfomycin ivEnterobacterales200 mcg2424FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
1246EUCAST 202010.0humanhumanMICNAEnterobacteralesNAFosfomycin oral (uncomplicated UTI only)EnterobacteralesNA3232FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
1247EUCAST 202010.0humanhumanDISKNAEnterobacteralesNAFosfomycin oral (uncomplicated UTI only)Enterobacterales200 mcg2424FALSEFALSEFALSE[2] Agar dilution is the reference method for fosfomycin. MICs must be determined in the presence of glucose-6-phosphate (25 mg/L in the medium). Follow the manufacturers' instructions for commercial systems. | [C] Zone diameter breakpoints apply to E. coli only. For other Enterobacterales, use an MIC method. | [D] Ignore isolated colonies within the inhibition zone (see pictures below).Enterobacterales
1248EUCAST 202010.0humanhumanMICNAEnterobacteralesNANitrofurantoin (uncomplicated UTI only), E. coliEnterobacteralesNA6464FALSEFALSEFALSENAEnterobacterales
1249EUCAST 202010.0humanhumanDISKNAEnterobacteralesNANitrofurantoin (uncomplicated UTI only), E. coliEnterobacterales100 mcg1111FALSEFALSEFALSENAEnterobacterales
1250EUCAST 202010.0humanhumanMICNAEnterobacteralesNANitroxoline (uncomplicated UTI only), E. coliEnterobacteralesNA1616FALSEFALSEFALSENAEnterobacterales
1251EUCAST 202010.0humanhumanDISKNAEnterobacteralesNANitroxoline (uncomplicated UTI only), E. coliEnterobacterales30 mcg1515FALSEFALSEFALSENAEnterobacterales
1252EUCAST 202010.0humanhumanMICNAEnterobacteralesNATrimethoprim (uncomplicated UTI only)EnterobacteralesNA44FALSEFALSEFALSENAEnterobacterales
1253EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATrimethoprim (uncomplicated UTI only)Enterobacterales5 mcg1515FALSEFALSEFALSENAEnterobacterales
1254EUCAST 202010.0humanhumanMICNAEnterobacteralesNATrimethoprim-sulfamethoxazoleEnterobacteralesNA24FALSEFALSEFALSENAEnterobacterales
1255EUCAST 202010.0humanhumanDISKNAEnterobacteralesNATrimethoprim-sulfamethoxazoleEnterobacterales1.25/23.75 mcg1411FALSEFALSEFALSENAEnterobacterales
1256EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAPiperacillinPseudomonas spp.NA0.00116FALSEFALSEFALSENAPseudomonas
1257EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAPiperacillinPseudomonas spp.30 mcg5018FALSEFALSEFALSENAPseudomonas
1258EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAPiperacillin-tazobactamPseudomonas spp.NA0.00116FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
1259EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAPiperacillin-tazobactamPseudomonas spp.30/6 mcg5018FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
1260EUCAST 202010.0humanhumanMICNAPseudomonas spp.NATicarcillinPseudomonas spp.NA0.00116FALSEFALSEFALSENAPseudomonas
1261EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NATicarcillinPseudomonas spp.75 mcg5018FALSEFALSEFALSENAPseudomonas
1262EUCAST 202010.0humanhumanMICNAPseudomonas spp.NATicarcillin-clavulanic acidPseudomonas spp.NA0.00116FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Pseudomonas
1263EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NATicarcillin-clavulanic acidPseudomonas spp.75/10 mcg5018FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of clavulanic acid is fixed at 2 mg/L.Pseudomonas
1264EUCAST 202010.0humanhumanMICNAPseudomonas spp.NACefepimePseudomonas spp.NA0.0018FALSEFALSEFALSENAPseudomonas
1265EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NACefepimePseudomonas spp.30 mcg5021FALSEFALSEFALSENAPseudomonas
1266EUCAST 202010.0humanhumanMICNAPseudomonas spp.NACeftazidimePseudomonas spp.NA0.0018FALSEFALSEFALSENAPseudomonas
1267EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NACeftazidimePseudomonas spp.10 mcg5017FALSEFALSEFALSENAPseudomonas
1268EUCAST 202010.0humanhumanMICNAPseudomonas spp.NACeftazidime-avibactam, P. aeruginosaPseudomonas spp.NA88FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Pseudomonas
1269EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NACeftazidime-avibactam, P. aeruginosaPseudomonas spp.10/4 mcg1717FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of avibactam is fixed at 4 mg/L.Pseudomonas
1270EUCAST 202010.0humanhumanMICNAPseudomonas spp.NACeftobiprolePseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1271EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NACeftobiprolePseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1272EUCAST 202010.0humanhumanMICNAPseudomonas spp.NACeftolozane-tazobactam, P. aeruginosaPseudomonas spp.NA44FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
1273EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NACeftolozane-tazobactam, P. aeruginosaPseudomonas spp.30/10 mcg2424FALSEFALSEFALSE[3] For susceptibility testing purposes, the concentration of tazobactam is fixed at 4 mg/L.Pseudomonas
1274EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAImipenemPseudomonas spp.NA0.0014FALSEFALSEFALSENAPseudomonas
1275EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAImipenemPseudomonas spp.10 mcg5020FALSEFALSEFALSENAPseudomonas
1276EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAImipenem-relebactam, P. aeruginosaPseudomonas spp.NA22FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of relebactam is fixed at 4 mg/L.Pseudomonas
1277EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAImipenem-relebactam, P. aeruginosaPseudomonas spp.IP mcgIPIPFALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of relebactam is fixed at 4 mg/L.Pseudomonas
1278EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAMeropenemPseudomonas spp.NA28FALSEFALSEFALSENAPseudomonas
1279EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAMeropenemPseudomonas spp.10 mcg2418FALSEFALSEFALSENAPseudomonas
1280EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAMeropenem-vaborbactam, P. aeruginosaPseudomonas spp.NA88FALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Pseudomonas
1281EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAMeropenem-vaborbactam, P. aeruginosaPseudomonas spp.IP mcgIPIPFALSEFALSEFALSE[2] For susceptibility testing purposes, the concentration of vaborbactam is fixed at 8 mg/L.Pseudomonas
1282EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAAztreonamPseudomonas spp.NA0.00116FALSEFALSEFALSENAPseudomonas
1283EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAAztreonamPseudomonas spp.30 mcg5018FALSEFALSEFALSENAPseudomonas
1284EUCAST 202010.0humanhumanMICNAPseudomonas spp.NACiprofloxacinPseudomonas spp.NA0.0010.5FALSEFALSEFALSENAPseudomonas
1285EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NACiprofloxacinPseudomonas spp.5 mcg5026FALSEFALSEFALSENAPseudomonas
1286EUCAST 202010.0humanhumanMICNAPseudomonas spp.NADelafloxacinPseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1287EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NADelafloxacinPseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1288EUCAST 202010.0humanhumanMICNAPseudomonas spp.NALevofloxacinPseudomonas spp.NA0.0011FALSEFALSEFALSENAPseudomonas
1289EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NALevofloxacinPseudomonas spp.5 mcg5022FALSEFALSEFALSENAPseudomonas
1290EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAAmikacin (systemic infections)Pseudomonas spp.NA1616FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Pseudomonas
1291EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAAmikacin (systemic infections)Pseudomonas spp.30 mcg1515FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Pseudomonas
1292EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAAmikacin (infections originating from the urinary tract)Pseudomonas spp.NA1616FALSEFALSEFALSENAPseudomonas
1293EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAAmikacin (infections originating from the urinary tract)Pseudomonas spp.30 mcg1515FALSEFALSEFALSENAPseudomonas
1294EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAGentamicin (systemic infections)Pseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1295EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAGentamicin (systemic infections)Pseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1296EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAGentamicin (infections originating from the urinary tract)Pseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1297EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAGentamicin (infections originating from the urinary tract)Pseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1298EUCAST 202010.0humanhumanMICNAPseudomonas spp.NANetilmicinPseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1299EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NANetilmicinPseudomonas spp.NAIEIEFALSEFALSEFALSENAPseudomonas
1300EUCAST 202010.0humanhumanMICNAPseudomonas spp.NATobramycin (systemic infections)Pseudomonas spp.NA22FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Pseudomonas
1301EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NATobramycin (systemic infections)Pseudomonas spp.10 mcg1818FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Pseudomonas
1302EUCAST 202010.0humanhumanMICNAPseudomonas spp.NATobramycin (infections originating from the urinary tract)Pseudomonas spp.NA22FALSEFALSEFALSENAPseudomonas
1303EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NATobramycin (infections originating from the urinary tract)Pseudomonas spp.10 mcg1818FALSEFALSEFALSENAPseudomonas
1304EUCAST 202010.0humanhumanMICNAPseudomonas spp.NAColistinPseudomonas spp.NA22FALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Pseudomonas
1305EUCAST 202010.0humanhumanDISKNAPseudomonas spp.NAColistinPseudomonas spp.NANoteNoteFALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Pseudomonas
1306EUCAST 202010.0humanhumanMICNAStenotrophomonas maltophiliaNATrimethoprim-sulfamethoxazoleStenotrophomonas maltophiliaNA0.0014FALSEFALSEFALSE[A] There may be growth within the inhibition zone. The density of growth may vary from a fine haze to substantial growth (see pictures below). If any zone edge can be seen, ignore growth within the inhibition zone and read the zone diameter.S.maltophilia
1307EUCAST 202010.0humanhumanDISKNAStenotrophomonas maltophiliaNATrimethoprim-sulfamethoxazoleStenotrophomonas maltophilia1.25/23.75 mcg5016FALSEFALSEFALSE[A] There may be growth within the inhibition zone. The density of growth may vary from a fine haze to substantial growth (see pictures below). If any zone edge can be seen, ignore growth within the inhibition zone and read the zone diameter.S.maltophilia
1308EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAAmpicillin-sulbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1309EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAAmpicillin-sulbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1310EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAPiperacillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1311EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAPiperacillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1312EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAPiperacillin-tazobactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1313EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAPiperacillin-tazobactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1314EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NATicarcillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1315EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NATicarcillinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1316EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NATicarcillin-clavulanic acidAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1317EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NATicarcillin-clavulanic acidAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1318EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAImipenemAcinetobacter spp.NA24FALSEFALSEFALSENAAcinetobacter
1319EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAImipenemAcinetobacter spp.10 mcg2421FALSEFALSEFALSENAAcinetobacter
1320EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAImipenem-relebactamAcinetobacter spp.NA22FALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of relebactam is fixed at 4 mg/L.Acinetobacter
1321EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAImipenem-relebactamAcinetobacter spp.IP mcgIPIPFALSEFALSEFALSE[1] For susceptibility testing purposes, the concentration of relebactam is fixed at 4 mg/L.Acinetobacter
1322EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAMeropenemAcinetobacter spp.NA28FALSEFALSEFALSENAAcinetobacter
1323EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAMeropenemAcinetobacter spp.10 mcg2115FALSEFALSEFALSENAAcinetobacter
1324EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAMeropenem-vaborbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1325EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAMeropenem-vaborbactamAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1326EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NACiprofloxacinAcinetobacter spp.NA0.0011FALSEFALSEFALSENAAcinetobacter
1327EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NACiprofloxacinAcinetobacter spp.5 mcg5021FALSEFALSEFALSENAAcinetobacter
1328EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NADelafloxacinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1329EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NADelafloxacinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1330EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NALevofloxacinAcinetobacter spp.NA0.51FALSEFALSEFALSENAAcinetobacter
1331EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NALevofloxacinAcinetobacter spp.5 mcg2320FALSEFALSEFALSENAAcinetobacter
1332EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAAmikacin (systemic infections)Acinetobacter spp.NA88FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Acinetobacter
1333EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAAmikacin (systemic infections)Acinetobacter spp.30 mcg1919FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Acinetobacter
1334EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAAmikacin (infections originating from the urinary tract)Acinetobacter spp.NA88FALSEFALSEFALSENAAcinetobacter
1335EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAAmikacin (infections originating from the urinary tract)Acinetobacter spp.30 mcg1919FALSEFALSEFALSENAAcinetobacter
1336EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAGentamicin (systemic infections)Acinetobacter spp.NA44FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Acinetobacter
1337EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAGentamicin (systemic infections)Acinetobacter spp.10 mcg1717FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Acinetobacter
1338EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAGentamicin (infections originating from the urinary tract)Acinetobacter spp.NA44FALSEFALSEFALSENAAcinetobacter
1339EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAGentamicin (infections originating from the urinary tract)Acinetobacter spp.10 mcg1717FALSEFALSEFALSENAAcinetobacter
1340EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NANetilmicinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1341EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NANetilmicinAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1342EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NATobramycin (systemic infections)Acinetobacter spp.NA44FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Acinetobacter
1343EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NATobramycin (systemic infections)Acinetobacter spp.10 mcg1717FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Acinetobacter
1344EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NATobramycin (infections originating from the urinary tract)Acinetobacter spp.NA44FALSEFALSEFALSENAAcinetobacter
1345EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NATobramycin (infections originating from the urinary tract)Acinetobacter spp.10 mcg1717FALSEFALSEFALSENAAcinetobacter
1346EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAEravacyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1347EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAEravacyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1348EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAMinocyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1349EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAMinocyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1350EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NATigecyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1351EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NATigecyclineAcinetobacter spp.NAIEIEFALSEFALSEFALSENAAcinetobacter
1352EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NAColistinAcinetobacter spp.NA22FALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Acinetobacter
1353EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NAColistinAcinetobacter spp.NANoteNoteFALSEFALSEFALSE[A] Use an MIC method (broth microdilution only).Acinetobacter
1354EUCAST 202010.0humanhumanMICNAAcinetobacter spp.NATrimethoprim-sulfamethoxazoleAcinetobacter spp.NA24FALSEFALSEFALSENAAcinetobacter
1355EUCAST 202010.0humanhumanDISKNAAcinetobacter spp.NATrimethoprim-sulfamethoxazoleAcinetobacter spp.1.25/23.75 mcg1411FALSEFALSEFALSENAAcinetobacter
1356EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NABenzylpenicillin,S. aureusStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [B] For S. aureus, disk diffusion is more reliable than MIC determination for detection of penicillinase producers, provided the zone diameter is measured AND the zone edge closely inspected (see pictures below). Examine the zone edge with transmitted light (plate held up to light). If the zone diameter is <26 mm, then report resistant. If the zone diameter is ≥26 mm AND the zone edge is sharp, then report resistant. If not sharp, then report susceptible and if uncertain, then report resistant. Chromogenic cephalosporin-based beta-lactamase tests do not reliably detect staphylococcal penicillinase.Staphylococcus
1357EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NABenzylpenicillin,S. aureusStaphylococcus spp.1 unit2626FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [B] For S. aureus, disk diffusion is more reliable than MIC determination for detection of penicillinase producers, provided the zone diameter is measured AND the zone edge closely inspected (see pictures below). Examine the zone edge with transmitted light (plate held up to light). If the zone diameter is <26 mm, then report resistant. If the zone diameter is ≥26 mm AND the zone edge is sharp, then report resistant. If not sharp, then report susceptible and if uncertain, then report resistant. Chromogenic cephalosporin-based beta-lactamase tests do not reliably detect staphylococcal penicillinase.Staphylococcus
1358EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NABenzylpenicillin,S. lugdunensisStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1359EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NABenzylpenicillin,S. lugdunensisStaphylococcus spp.1 unit2626FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1360EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NABenzylpenicillin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci.Staphylococcus
1361EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAmpicillin,S. saprophyticusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1362EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAmpicillin,S. saprophyticusStaphylococcus spp.2 mcg1818FALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1363EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAmpicillin-sulbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1364EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAmpicillin-sulbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1365EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAmoxicillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1366EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAmoxicillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1367EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAmoxicillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1368EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAmoxicillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1369EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAPiperacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1370EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAPiperacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1371EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAPiperacillin-tazobactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1372EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAPiperacillin-tazobactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [3/D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1373EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATicarcillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci.Staphylococcus
1374EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATicarcillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci.Staphylococcus
1375EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATicarcillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1376EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATicarcillin-clavulanic acidStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1377EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAPhenoxymethylpenicillin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1378EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAPhenoxymethylpenicillin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1379EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAPhenoxymethylpenicillin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [2/C] No currently available method can reliably detect penicillinase production in coagulase-negative staphylococci. | [D] Ampicillin susceptible S. saprophyticus are mecA-negative and susceptible to ampicillin, amoxicillin and piperacillin (without or with a beta-lactamase inhibitor). 4.S. aureus,S. lugdunensis and S. saprophyticus with oxacillin MIC values >2 mg/L are mostly methicillin resistant due to the presence of the mecA or mecC gene. Occasionally oxacillin MIC values are high in S. aureus in absence of mec-gene mediated resistance. These strains have been called BORSA (borderline oxacillin resistant S. aureus). EUCAST does not recommend systematic screening for BORSA. For coagulase-negative staphylococci other than S. saprophyticus and S. lugdunensis, the oxacillin MIC in methicillin resistant strains is >0.25 mg/L.Staphylococcus
1380EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAOxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [E] For screening for methicillin resistance in S. pseudintermedius and S. schleiferi, see Note C on cephalosporins.Staphylococcus
1381EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAOxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins. | [E] For screening for methicillin resistance in S. pseudintermedius and S. schleiferi, see Note C on cephalosporins.Staphylococcus
1382EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1383EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1384EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NADicloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1385EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NADicloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1386EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAFlucloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1387EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAFlucloxacillinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Most staphylococci are penicillinase producers and some are methicillin resistant. Either mechanism renders them resistant to benzylpenicillin, phenoxymethylpenicillin, ampicillin, amoxicillin, piperacillin and ticarcillin. Staphylococci that test susceptible to benzylpenicillin and cefoxitin can be reported susceptible to all penicillins. Staphylococci that test resistant to benzylpenicillin but susceptible to cefoxitin are susceptible to β-lactamase inhibitor combinations, the isoxazolylpenicillins (oxacillin, cloxacillin, dicloxacillin and flucloxacillin) and nafcillin. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. Staphylococci that test resistant to cefoxitin are resistant to all penicillins.Staphylococcus
1388EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefaclorStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1389EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefaclorStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1390EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefadroxilStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1391EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefadroxilStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1392EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefalexinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1393EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefalexinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1394EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefazolinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1395EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefazolinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1396EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefepimeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1397EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefepimeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1398EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefotaximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1399EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefotaximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1400EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefoxitin (screen only), S. aureus and coagulase-negative staphylococci other than S. epidermidisStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[4] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
1401EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefoxitin (screen only), S. aureus and coagulase-negative staphylococci other than S. epidermidisStaphylococcus spp.30 mcg2222FALSEFALSEFALSE[4] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
1402EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefoxitin (screen only), S. epidermidisStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[4] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
1403EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefoxitin (screen only), S. epidermidisStaphylococcus spp.30 mcg2525FALSEFALSEFALSE[4] For staphylococci other than S. aureus, S. lugdunensis and S. saprophyticus, the cefoxitin MIC is a poorer predictor of methicillin resistance than the disk diffusion test. | [A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F. | [B] If coagulase-negative staphylococci are not identified to species level, use zone diameter breakpoints S≥25, R<25 mm.Staphylococcus
1404EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefoxitin (screen only), S. pseudintermedius and S. schleiferiStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[C] Cefoxitin screen for methicillin resistance in S. pseudintermediusand S. schleiferi is less predictive of the presence of mecA than in other staphylococci. Use the oxacillin 1 µg disk with zone diameter breakpoints S≥20, R<20 mm to screen for methicillin resistance.Staphylococcus
1405EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefpodoximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1406EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefpodoximeStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1407EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACeftaroline, S. aureus (indications other than pneumonia)Staphylococcus spp.NA12FALSEFALSEFALSE[5/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
1408EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACeftaroline, S. aureus (indications other than pneumonia)Staphylococcus spp.5 mcg2017FALSEFALSEFALSE[5/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
1409EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACeftaroline, S. aureus (pneumonia)Staphylococcus spp.NA11FALSEFALSEFALSE[5/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
1410EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACeftaroline, S. aureus (pneumonia)Staphylococcus spp.5 mcg2020FALSEFALSEFALSE[5/D] Methicillin-susceptible isolates can be reported susceptible to ceftaroline without further testing.Staphylococcus
1411EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACeftobiprole, S. aureusStaphylococcus spp.NA22FALSEFALSEFALSE[7/F] Methicillin-susceptible isolates can be reported susceptible to ceftobiprole without further testing.Staphylococcus
1412EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACeftobiprole, S. aureusStaphylococcus spp.5 mcg1717FALSEFALSEFALSE[7/F] Methicillin-susceptible isolates can be reported susceptible to ceftobiprole without further testing.Staphylococcus
1413EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACeftriaxoneStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1414EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACeftriaxoneStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1415EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefuroxime ivStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1416EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefuroxime ivStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1417EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACefuroxime oralStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1418EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACefuroxime oralStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to cephalosporins is inferred from the cefoxitin susceptibility except for cefixime, ceftazidime, ceftazidime-avibactam, ceftibuten and ceftolozane-tazobactam, which do not have breakpoints and should not be used for staphylococcal infections. For agents given orally, care to achieve sufficient exposure at the site of the infection should be exercised. If cefotaxime and ceftriaxone are reported for methicillin-susceptible staphylococci, these should be reported “Susceptible, increased exposure” (I). Some methicillin-resistant S. aureus are susceptible to ceftaroline and ceftobiprole, see Notes 5/D and 7/F.Staphylococcus
1419EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAErtapenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1420EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAErtapenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1421EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAImipenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1422EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAImipenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1423EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAImipenem-relebactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1424EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAImipenem-relebactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1425EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAMeropenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1426EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAMeropenemStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1427EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAMeropenem-vaborbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1428EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAMeropenem-vaborbactamStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Susceptibility of staphylococci to carbapenems is inferred from the cefoxitin susceptibility.Staphylococcus
1429EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACiprofloxacin, S. aureusStaphylococcus spp.NA0.0011FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1430EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACiprofloxacin, S. aureusStaphylococcus spp.5 mcg5021FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1431EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NACiprofloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA0.0011FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1432EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NACiprofloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg5024FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1433EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NADelafloxacin, S. aureusStaphylococcus spp.NA0.250.25FALSEFALSEFALSE[B] A disk diffusion test is not yet developed. Perform an MIC test. C.Isolates categorised as susceptible to norfloxacin can be reported susceptible to moxifloxacin and "susceptible increased exposure" (I) to ciprofloxacin, levofloxacin and ofloxacin. Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Staphylococcus
1434EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NADelafloxacin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[B] A disk diffusion test is not yet developed. Perform an MIC test. C.Isolates categorised as susceptible to norfloxacin can be reported susceptible to moxifloxacin and "susceptible increased exposure" (I) to ciprofloxacin, levofloxacin and ofloxacin. Isolates categorised as non-susceptible should be tested for susceptibility to individual agents.Staphylococcus
1435EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NALevofloxacin, S. aureusStaphylococcus spp.NA0.0011FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1436EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NALevofloxacin, S. aureusStaphylococcus spp.5 mcg5022FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1437EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NALevofloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA0.0011FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1438EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NALevofloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg5024FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1439EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAMoxifloxacin, S. aureusStaphylococcus spp.NA0.250.25FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1440EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAMoxifloxacin, S. aureusStaphylococcus spp.5 mcg2525FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1441EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAMoxifloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA0.250.25FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1442EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAMoxifloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg2828FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1443EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NANorfloxacin (screen only)Staphylococcus spp.10 mcg17NoteFALSEFALSEFALSE[C] Staphylococcus
1444EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAOfloxacin, S. aureusStaphylococcus spp.NA0.0011FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1445EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAOfloxacin, S. aureusStaphylococcus spp.5 mcg5020FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1446EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAOfloxacin, Coagulase-negative staphylococciStaphylococcus spp.NA0.0011FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1447EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAOfloxacin, Coagulase-negative staphylococciStaphylococcus spp.5 mcg5024FALSEFALSEFALSE[A] The norfloxacin disk diffusion test can be used to screen for fluoroquinolone resistance. See NoteStaphylococcus
1448EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAmikacin, S. aureusStaphylococcus spp.NA88FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1449EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAmikacin, S. aureusStaphylococcus spp.30 mcg1818FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1450EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAmikacin, Coagulase-negative staphylococciStaphylococcus spp.NA88FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1451EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAmikacin, Coagulase-negative staphylococciStaphylococcus spp.30 mcg2222FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1452EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAGentamicin, S. aureusStaphylococcus spp.NA11FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1453EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAGentamicin, S. aureusStaphylococcus spp.10 mcg1818FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1454EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAGentamicin,Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1455EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAGentamicin,Coagulase-negative staphylococciStaphylococcus spp.10 mcg2222FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1456EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NANetilmicinStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
1457EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NANetilmicinStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
1458EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATobramycin, S. aureusStaphylococcus spp.NA11FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1459EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATobramycin, S. aureusStaphylococcus spp.10 mcg1818FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1460EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATobramycin, Coagulase-negative staphylococciStaphylococcus spp.NA11FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1461EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATobramycin, Coagulase-negative staphylococciStaphylococcus spp.10 mcg2222FALSEFALSETRUE[1/A] For systemic infections, aminoglycosides must be used in combination with other active therapy. In this circumstance, the breakpoint/ECOFF in brackets can be used to distinguish between organisms with and without acquired resistance mechanisms. For isolates without resistance mechanisms, include a comment in the report: “Aminoglycosides are often given in combination with other agents, either to support the activity of the aminoglycoside or to broaden the spectrum of therapy. In systemic infections, the aminoglycoside must be supported by other active therapy." For more information, see http://www.eucast.org/guidance_documents/.Staphylococcus
1462EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NADalbavancinStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[3] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [4] S. aureus isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1463EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NADalbavancinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[3] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [4] S. aureus isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1464EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAOritavancin, S. aureusStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[3] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [4] S. aureus isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1465EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAOritavancin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[3] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [4] S. aureus isolates susceptible to vancomycin can be reported susceptible to dalbavancin and oritavancin. | [A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1466EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATeicoplanin, S. aureusStaphylococcus spp.NA22FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1467EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATeicoplanin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1468EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATeicoplanin, Coagulase-negative staphylococciStaphylococcus spp.NA44FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1469EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATeicoplanin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1470EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATelavancin,MRSAStaphylococcus spp.NA0.1250.125FALSEFALSEFALSE[3] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [5] MRSA isolates susceptible to vancomycin can be reported susceptible to telavancin. | [A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1471EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATelavancin,MRSAStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[3] MICs must be determined in the presence of polysorbate-80 (0.002% in the medium for broth dilution methods; agar dilution methods have not been validated). Follow the manufacturer's instructions for commercial systems. | [5] MRSA isolates susceptible to vancomycin can be reported susceptible to telavancin. | [A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1472EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAVancomycin, S. aureusStaphylococcus spp.NA22FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1473EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAVancomycin, S. aureusStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1474EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAVancomycin, Coagulase-negative staphylococciStaphylococcus spp.NA44FALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1475EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAVancomycin, Coagulase-negative staphylococciStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[A] Disk diffusion is unreliable and cannot distinguish between wild type isolates and those with non-vanA-mediated glycopeptide resistance.Staphylococcus
1476EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAAzithromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1477EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAAzithromycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1478EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAClarithromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1479EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAClarithromycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1480EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAErythromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1481EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAErythromycinStaphylococcus spp.15 mcg2118FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1482EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NARoxithromycinStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1483EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NARoxithromycinStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Erythromycin can be used to determine susceptibility to azithromycin, clarithromycin and roxithromycin.Staphylococcus
1484EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATelithromycinStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
1485EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATelithromycinStaphylococcus spp.NAIEIEFALSEFALSEFALSENAStaphylococcus
1486EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAClindamycinStaphylococcus spp.NA0.250.5FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-20 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Staphylococcus
1487EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAClindamycinStaphylococcus spp.2 mcg2219FALSEFALSEFALSE[B] Place the erythromycin and clindamycin disks 12-20 mm apart (edge to edge) and look for antagonism (the D phenomenon) to detect inducible clindamycin resistance.Staphylococcus
1488EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAQuinupristin-dalfopristinStaphylococcus spp.NA12FALSEFALSEFALSENAStaphylococcus
1489EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAQuinupristin-dalfopristinStaphylococcus spp.15 mcg2118FALSEFALSEFALSENAStaphylococcus
1490EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NADoxycyclineStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
1491EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NADoxycyclineStaphylococcus spp.NANoteNoteFALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
1492EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAEravacycline, S. aureusStaphylococcus spp.NA0.250.25FALSEFALSEFALSE[B] The zone diameter breakpoint is valid for MSSA only. For MRSA, perform an MIC test.Staphylococcus
1493EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAEravacycline, S. aureusStaphylococcus spp.20 mcg2020FALSEFALSEFALSE[B] The zone diameter breakpoint is valid for MSSA only. For MRSA, perform an MIC test.Staphylococcus
1494EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAMinocyclineStaphylococcus spp.NA0.50.5FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
1495EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAMinocyclineStaphylococcus spp.30 mcg2323FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
1496EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATetracyclineStaphylococcus spp.NA12FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
1497EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATetracyclineStaphylococcus spp.30 mcg2219FALSEFALSEFALSE[1/A] Isolates susceptible to tetracycline are also susceptible to doxycycline and minocycline, but some resistant to tetracycline may be susceptible to minocycline and/or doxycycline. An MIC method should be used to test doxycycline susceptibility of tetracycline resistant isolates if required.Staphylococcus
1498EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATigecyclineStaphylococcus spp.NA0.50.5FALSEFALSEFALSE[3] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Staphylococcus
1499EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATigecyclineStaphylococcus spp.15 mcg1919FALSEFALSEFALSE[3] For tigecycline broth microdilution MIC determination, the medium must be prepared fresh on the day of use.Staphylococcus
1500EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NALinezolidStaphylococcus spp.NA44FALSEFALSEFALSENAStaphylococcus
1501EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NALinezolidStaphylococcus spp.10 mcg2121FALSEFALSEFALSENAStaphylococcus
1502EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NATedizolidStaphylococcus spp.NA0.50.5FALSEFALSEFALSE[1/A] Isolates susceptible to linezolid can be reported susceptible to tedizolid.Staphylococcus
1503EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NATedizolidStaphylococcus spp.2 mcg2121FALSEFALSEFALSE[1/A] Isolates susceptible to linezolid can be reported susceptible to tedizolid.Staphylococcus
1504EUCAST 202010.0humanhumanMICNAStaphylococcus spp.NAChloramphenicolStaphylococcus spp.NA88FALSEFALSEFALSENAStaphylococcus
1505EUCAST 202010.0humanhumanDISKNAStaphylococcus spp.NAChloramphenicolStaphylococcus spp.30 mcg1818FALSEFALSEFALSENAStaphylococcus
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